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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DCDC2 Gene

protein-coding GIFtS: 52
GCID: GC06M024122

doublecortin domain containing 2

Explore 5 diseases affiliated with
DCDC2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Doublecortin Domain Containing 2¹ ²		RU2S²
RU2¹ ² ³ ⁵		Doublecortin Domain-Containing Protein 2²
KIAA1154¹ ³ ⁵		Protein RU2S³
DCDC2A¹ ²

External Ids:	HGNC: 18141¹	Entrez Gene: 51473²	Ensembl: ENSG00000146038⁷	OMIM: 605755⁵	UniProtKB: Q9UHG0³

Export aliases for DCDC2 gene to outside databases

Previous GC identifers: GC06M024233 GC06M024254 GC06M024277

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DCDC2:

This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind

tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where

it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD)

type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same

protein have been found for this gene. (provided by RefSeq, Jan 2013)

UniProtKB/Swiss-Prot: DCDC2_HUMAN, Q9UHG0

Function: May be involved in neuronal migration during development of the cerebral neocortex (By similarity)

Gene Wiki entry for DCDC2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.1 NT_007592.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DCDC2 gene promoter:
E2F-3a E2F-4 NF-1 E2F-5 E2F-2 E47 GATA-1 E2F-1 E2F Pax-4a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DCDC2 promoter sequence

Search SABiosciences Chromatin IP Primers for DCDC2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCDC2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.1 Ensembl cytogenetic band: 6p22.3 HGNC cytogenetic band: 6p22.1

DCDC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCDC2 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M024122: view genomic region (about GC identifiers)

Start:	24,171,983 bp from pter	End:	24,358,280 bp from pter
Size:	186,298 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DCDC2_HUMAN, Q9UHG0 (See protein sequence)

Recommended Name: Doublecortin domain-containing protein 2

Size: 476 amino acids; 52834 Da

Sequence caution: Sequence=CAB61371.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

1 PDB 3D structure from and Proteopedia for DCDC2:

2DNF (3D)

Secondary accessions: Q5VTR8 Q5VTR9 Q86W35 Q9UFD1 Q9UHG1 Q9ULR6

Alternative splicing: 2 isoforms: Q9UHG0-1 Q9UHG0-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DCDC2: NX_Q9UHG0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9UHG0

DCDC2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001182539.1 NP_057440.2

ENSEMBL proteins:

ENSP00000367715 ENSP00000367711 ENSP00000410939

Human Recombinant Protein Products:

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	Uscn Proteins for DCDC2

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--

DCDC2 for ontologies About GeneDecksing

DCDC2 Antibody Products:

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Assay Products for DCDC2:

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	Uscn ELISAs and CLIAs for DCDC2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DCDC2 for domains About GeneDecksing

1 InterPro domain/family:

IPR003533 Doublecortin_dom

Graphical View of Domain Structure for InterPro Entry Q9UHG0

ProtoNet protein and cluster: Q9UHG0

UniProtKB/Swiss-Prot: DCDC2_HUMAN, Q9UHG0

Similarity: Contains 2 doublecortin domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: DCDC2_HUMAN, Q9UHG0

Function: May be involved in neuronal migration during development of the cerebral neocortex (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: DCDC2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DCDC2
		8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate DCDC2 (see all 31):
		hsa-miR-495 hsa-miR-520e hsa-miR-302d hsa-miR-429 hsa-miR-137 hsa-miR-302e hsa-miR-410 hsa-miR-3167

		SwitchGear 3'UTR luciferase reporter plasmid: DCDC2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for DCDC2

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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for DCDC2
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCDC2

1 GenomeRNAi human phenotype for DCDC2:

Synthetic lethal with Ras

Animal Models:
Mouse knock-out Dcdc2a^tm1.2Jjlo for DCDC2
2 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Dcdc2a):

behavior/neurological

nervous system

DCDC2 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for DCDC2

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001764	neuron migration	NAS	16278297
GO:0006968	cellular defense response	TAS	10601354
GO:0035556	intracellular signal transduction	IEA	--
GO:0048813	dendrite morphogenesis	IEA	--

DCDC2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DCDC2
Search CenterWatch for drugs/clinical trials and news about DCDC2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DCDC2 gene (2 alternative transcripts):

NM_001195610.1 NM_016356.4

Unigene Cluster for DCDC2:

Doublecortin domain containing 2

Hs.61345 [show with all ESTs]

Unigene Representative Sequence: AB032980

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000378454(uc003ndx.3 uc003ndy.3) ENST00000378450(uc003ndw.3)

ENST00000436313

miRNA Products:		OriGene 3'-UTR Clone: DCDC2 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DCDC2
		8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate DCDC2 (see all 31):
		hsa-miR-495 hsa-miR-520e hsa-miR-302d hsa-miR-429 hsa-miR-137 hsa-miR-302e hsa-miR-410 hsa-miR-3167

		SwitchGear 3'UTR luciferase reporter plasmid: DCDC2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DCDC2 (see all 4) OriGene shRNA RFP: DCDC2 OriGene siRNA: DCDC2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DCDC2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DCDC2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DCDC2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): DCDC2 (NM_001195610)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DCDC2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCDC2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DCDC2 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DCDC2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCDC2

Additional cDNA sequence:

AB032980.2 AF181721.1 AK027036.1 BC050704.1

7 DOTS entries:

DT.40245473 DT.95261613 DT.100820887 DT.100820888 DT.92013933 DT.92421305 DT.86851207

24/56 AceView cDNA sequences (see all 56):

AI858903 AF181721 CD722449 BQ644474 AW444617 BF593580 BQ644671 AW150317

CR611697 AA127741 BQ650550 NM_016356 BM833169 BQ948660 AA127805 BM927835

AA026454 AI219704 BX279966 AW293816 BE139585 N43170 AK027036 AW965006

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DCDC2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

DCDC2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)

Intermediate Mesoderm, Kidney

See DCDC2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DCDC2

SOURCE GeneReport for Unigene cluster: Hs.61345

UniProtKB/Swiss-Prot: DCDC2_HUMAN, Q9UHG0

Tissue specificity: Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal

cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus

SABiosciences Custom PCR Arrays for DCDC2

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCDC2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCDC2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for DCDC2 gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Dcdc2a^{1 , 5}	doublecortin domain containing 2a^{1, 5}	82.81(n)¹ 83.37(a)¹		13 (10.89 cM)⁵ 195208¹ NM_177577.3¹ NP_808245.2¹ 25056004⁵
chicken (Gallus gallus)	Aves	LOC420821¹	doublecortin domain-containing protein 2-like	69.15(n) 63.54(a)		420821 XM_003640752.1 XP_003640800.1
lizard (Anolis carolinensis)	Reptilia	DCDC2⁶	--	71(a)	1 ↔ 1	4(54163384-54198528)
African clawed frog (Xenopus laevis)	Amphibia	MGC52970²	similar to RU2S	74.55(n)		BC046665.1
zebrafish (Danio rerio)	Actinopterygii	dcdc2b¹	doublecortin domain containing 2B	52.85(n) 45.94(a)		563259 NM_001037689.1 NP_001032778.1

ENSEMBL Gene Tree for DCDC2 (if available)
TreeFam Gene Tree for DCDC2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DCDC2 gene

DCDC2B² DCDC2C²

2 SIMAP similar genes for DCDC2 using alignment to 2 protein entries: DCDC2_HUMAN (see all proteins):

DCDC2C DCDC2B

DCDC2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Pop	Total sample
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs75845847^1,2	C,F,	--	24121549(+)	`CACAGT/ATTTTT`	2	--	ds500¹		2	WA CSA	4
rs77839144^1,2	C,F,	--	24121554(+)	`ATTTTC/TTTCTA`	2	--	ds500¹		2	WA CSA	4
rs74945887^1,2	F,	--	24121641(+)	`AAATTG/AGAAGA`	2	--	ds500¹		1	NA	120
rs41304906^1,2	F,	--	24122402(+)	`CAGCAT/ATTATG`	2	--	ut3¹		1	NA	120
rs78473954^1,2	F,	--	24122516(+)	`AAGTGA/GTAAGT`	2	--	ut3¹		1	EA	120
rs41304913^1,2	C,F,	--	24122554(+)	`CAATTG/ATATCT`	2	--	ut3¹		1	NA	120
rs60947379^1,2	C,F,	--	24122648(+)	`ATTACC/TCCCTT`	2	--	ut3¹		1	WA	118
rs61431152^1,2	C,F,	--	24122695(+)	`TAAAAT/CATCAA`	2	--	ut3¹		1	WA	118
rs12333271^1,2	C,F,	--	24122774(+)	`AAGGAC/TAGGAA`	2	--	ut3¹ ese³		5	WA CSA NA	243
rs12333304^1,2	C,F,A,H,	--	24122839(+)	`AGAAAC/GAAAAG`	2	--	ut3¹		8	NS EA WA CSA	543

HapMap Linkage Disequilibrium report for DCDC2 (24171983 - 24358280 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 13 variations for DCDC2
11 CNVs: 7552 81275 81274 93549 7553 93547 93546 93548 62484 81273 64453
2 Indels: 99465 11274
Human Gene Mutation Database (HGMD): DCDC2

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DCDC2

DNA2.0 Custom Variant and Variant Library Synthesis for DCDC2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DCDC2 for disorders About GeneDecksing

OMIM gene information: 605755 OMIM disorders: --

UniProtKB/Swiss-Prot: DCDC2_HUMAN, Q9UHG0

Defects in DCDC2 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as

specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10%

of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate

motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability

5 diseases for DCDC2: About MalaCards

dyslexia attention deficit hyperactivity disorder cerebritis schizophrenia

neuronitis

2 diseases from the University of Copenhagen DISEASES database for DCDC2:

Dyslexia Writing disorder

Human Genome Epidemiology (HuGE) Navigator: DCDC2 (21 documents)

Export disorders for DCDC2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DCDC2 gene, integrated from 9 sources (see all 43):
(articles sorted by number of sources associating them with DCDC2)

Utopia: connect your pdf to the dynamic
world of online information

Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)^{1, 2, 3} Hirosawa M.... Ohara O. (1999)
A new antigen recognized by cytolytic T lymphocytes on a human kidney tumor results from reverse strand transcription. (PubMed id 10601354)^{1, 2, 3} Van den Eynde B.J.... Boon T. (1999)
DCDC2 is associated with reading disability and modulates neuronal development in the brain. (PubMed id 16278297)^{1, 2} Meng H....Gruen J.R. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (2003)
Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)^{1, 2} Nakajima D.... Nagase T. (2002)
Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample. (PubMed id 19018237)^{1, 9} Ludwig K.U....Hoffmann P. (2008)
Meta-analysis of the association between DCDC2 polymor phisms and risk of dyslexia. (PubMed id 23229871)¹ Zhong R....Miao X. (2013)
Exploring the transcriptome of ciliated cells using in silico dissection of human tissues. (PubMed id 22558177)¹ Ivliev A.E....Sergeeva M.G. (2012)
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. (PubMed id 22837378)¹ Wilk J.B....Stricker B.H. (2012)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 51473	HGNC: 18141	AceView: DCDC2	Ensembl:ENSG00000146038	euGenes: HUgn51473
ECgene: DCDC2	H-InvDB: DCDC2

(According to HUGE)
About This Section

HUGE: KIAA1154

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DCDC2	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for DCDC2	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for DCDC2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for DCDC2 gene:
Search GeneIP for patents involving DCDC2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	OriGene Antibodies for DCDC2		OriGene shRNA RFP for DCDC2
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DCDC2		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DCDC2
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	OriGene siRNA for DCDC2		OriGene 3'-UTR Clone for DCDC2
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DCDC2
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DCDC2
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCDC2
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DCDC2
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCDC2
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DCDC2

	GenScript Custom Purified and Recombinant Proteins Services for DCDC2		GenScript cDNA clones with any tag delivered in your preferred vector for DCDC2
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCDC2

	SwitchGear 3'UTR luciferase reporter plasmids for DCDC2
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ThermoFisher Antibodies for DCDC2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCDC2

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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DCDC2 Gene

doublecortin domain containing 2

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DCDC2 Gene

doublecortin domain containing 2

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