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Aliases & Descriptions for DCDC1
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| | | Descriptions |
|---|
| doublecortin domain containing 1 2 |
|
| | Search outside databases for aliases for DCDC1 genePrevious GC identifers: GC00U900980 GC11M031248 |
Summaries for DCDC1(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Location for DCDC1
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the DCDC1 gene 
Entrez Gene cytogenetic band: 11p13 Ensembl cytogenetic band: 11p13 HGNC cytogenetic band: 11p14.1DCDC1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M031240:
(about GC identifiers)
Start:
|
31,240,747 bp from pter |
End:
|
31,347,933 bp from pter |
Size:
|
107,187 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000011.8 NT_009237.17
| Proteins for DCDC1
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: DCDC1_HUMAN, P59894 (See
protein sequence)Recommended Name: Doublecortin domain-containing protein 1 Size: 354 amino acids; 39859 Da
Secondary accessions: A6PVL6REFSEQ proteins: NP_861523.2
ENSEMBL proteins: ENSP00000335085
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for DCDC1: Assays for DCDC1: | Protein
Domains/ Families for DCDC1(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P59894
ProtoNet protein and cluster: P59894 UniProtKB/Swiss-Prot: DCDC1_HUMAN, P59894Similarity: Contains 1 doublecortin domain | Gene Function for DCDC1
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_181807
Applied Biosystems Silencer® siRNAs for DCDC1
Sigma-Aldrich siRNA for DCDC1  Sigma-Aldrich shRNA for DCDC1  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_181807                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_181807                                  untagged cDNA clone in CMV expression vector: NM_181807 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_181807
| Pathways & Interactions for DCDC1
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
1 Interacting protein for DCDC1 (ENSP000003350853) via UniProtKB, MINT, and/or STRINGAbout this table
1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007242 | intracellular signaling cascade |
IEA | -- | About this table
|
Drugs & Compounds for DCDC1(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for DCDC1
|
Transcripts for DCDC1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_181807
Sigma-Aldrich siRNA for DCDC1  Sigma-Aldrich shRNA for DCDC1  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_181807 REFSEQ mRNAs for DCDC1 gene: NM_181807.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_181807               OriGene GFP tagged cDNA clone in CMV expression vector: NM_181807                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_181807                                  untagged cDNA clone in CMV expression vector: NM_181807  Additional cDNA sequence: AY247970.1 3 DOTS entries: DT.40126928 DT.40125715 DT.101955217 24/29 AceView cDNA sequences (see all 29
):NM_198462 BX097338 AA833549 BX117620 AI056882 AK126066 AA004887 AA005095 AA846321 AI040110 AB040926 AW340116 BX116244 BX647348 AK128035 NM_181807 AI150472 AA954541 AY247970 AI243215 BF957112 AI684432 AA680369 AL713024
highest scoring ESTs for DCDC1:AY247970 DB090201 AA846321 AA954541 CD693370 NM_181807 DB301632 AI684432 BX097338 AL713024 Unigene Cluster for DCDC1: Doublecortin domain containing 1 Hs.592000 [show with all ESTs]Unigene Representative Sequence: AY247970
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000354034
|
Expression for DCDC1
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| DCDC1 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for DCDC1
1 / 2 / 3 2 probe-sets matching DCDC1 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: TGGAAGCATT
SOURCE GeneReport for Unigene cluster: Hs.592000 UniProtKB/Swiss-Prot: DCDC1_HUMAN, P59894Tissue specificity: Highly expressed in testis. Lower levels of expression in lung, kidney, and pancreas. Higher expression in fetal brain than in adult brain |
Orthologs for DCDC1
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for DCDC1 gene from 3 species
About this table Species with no ortholog for DCDC1
ENSEMBL Gene Tree for DCDC1 | Paralogs for DCDC1(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
SNPs/Variants for DCDC1(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for DCDC1 (up to first 250kb)
|
Disorders & Mutations for DCDC1
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 608062
|
Medical News for DCDC1(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for DCDC1 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 2 PubMed articles for DCDC1 gene: |
Search for DCDC1
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing DCDC1
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing DCDC1
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DCDC1(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for DCDC1(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for DCDC1:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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