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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DCBLD2 Gene

protein-coding   GIFtS: 59
GCID: GC03M098514

Discoidin, CUB And LCCL Domain Containing 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Discoidin, CUB And LCCL Domain Containing 21 2     CUB, LCCL And Coagulation Factor V/VIII-Homology Domains Protein 12 3
Endothelial And Smooth Muscle Cell-Derived Neuropilin-Like Protein2 3     1700055P21Rik2
CLCP12 3     Coagulation Factor V/VIII-Homology Domains Protein 12
ESDN2 3     Discoidin, CUB And LCCL Domain-Containing Protein 22

External Ids:    HGNC: 246271   Entrez Gene: 1315662   Ensembl: ENSG000000570197   OMIM: 6086985   UniProtKB: Q96PD23   

Export aliases for DCBLD2 gene to outside databases

Previous GC identifers: GC03M099836 GC03M099997 GC03M095886


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DCBLD2 Gene: 
DCBLD2 (discoidin, CUB and LCCL domain containing 2) is a protein-coding gene. Diseases associated with DCBLD2 include arteriosclerosis, and endotheliitis. An important paralog of this gene is DCBLD1.

Gene Wiki entry for DCBLD2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DCBLD2 gene promoter:
         GATA-3   p53   Pax-2   Pax-2a   POU6F1 (c2)   POU3F2   MEF-2A   Pax-2b   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDCBLD2 promoter sequence
   Search SABiosciences Chromatin IP Primers for DCBLD2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCBLD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q12.1|3   Ensembl cytogenetic band:  3q12.1   HGNC cytogenetic band: 3q12.2

DCBLD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCBLD2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M098514:  view genomic region     (about GC identifiers)

Start:
98,514,785 bp from pter      End:
98,620,533 bp from pter
Size:
105,749 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DCBD2_HUMAN, Q96PD2 (See protein sequence)
Recommended Name: Discoidin, CUB and LCCL domain-containing protein 2 precursor  
Size: 775 amino acids; 85035 Da
Subcellular location: Membrane; Single-pass type I membrane protein
Secondary accessions: B7WNL1 D3DN41 Q8N6M4 Q8TDX2
Alternative splicing: 2 isoforms:  Q96PD2-1   Q96PD2-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DCBLD2: NX_Q96PD2

Explore proteomics data for DCBLD2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96PD2

  • DCBLD2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DCBLD2 Protein Expression
    REFSEQ proteins: NP_563615.3  
    ENSEMBL proteins: 
     ENSP00000321573   ENSP00000321646   ENSP00000396803  

    Human Recombinant Protein Products for DCBLD2: 
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    Novus Biologicals DCBLD2 Proteins
    Novus Biologicals DCBLD2 Lysate
    Sino Biological Recombinant Protein for DCBLD2
    Sino Biological Cell Lysate for DCBLD2 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DCBLD2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral to plasma membrane IDA11447234
    GO:0009986cell surface IDA11447234

    DCBLD2 for ontologies           About GeneDecksing



    DCBLD2 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR004043 LCCL
     IPR008979 Galactose-bd-like
     IPR000859 CUB_dom
     IPR000421 Coagulation_fac_5/8-C_type_dom

    Graphical View of Domain Structure for InterPro Entry Q96PD2

    ProtoNet protein and cluster: Q96PD2

    2 Blocks protein domains:
    IPB000421 Coagulation factor 5/8 type C domain (FA58C)
    IPB000859 CUB domain


    UniProtKB/Swiss-Prot: DCBD2_HUMAN, Q96PD2
    Similarity: Contains 1 CUB domain
    Similarity: Contains 1 F5/8 type C domain
    Similarity: Contains 1 LCCL domain


    DCBLD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DCBD2_HUMAN, Q96PD2
    Induction: Increased in lung cancers during the process of tumor progression

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    DCBLD2 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for DCBLD2:
     Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DCBLD2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DCBLD2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DCBLD2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DCBLD2 

    miRNA
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    miRTarBase miRNAs that target DCBLD2:
    hsa-mir-197 (MIRT004182)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DCBLD2
    8/123 QIAGEN miScript miRNA Assays for microRNAs that regulate DCBLD2 (see all 123):
    hsa-miR-579 hsa-miR-300 hsa-miR-106a hsa-miR-1224-3p hsa-miR-199a-3p hsa-miR-15a hsa-miR-128 hsa-miR-1260b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCBLD2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DCBLD2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Neuroscience
    Neuroscience

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for DCBLD2
        Neuroscience




    DCBLD2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DCBLD2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/6 Interacting proteins for DCBLD2 (Q96PD22 ENSP000003215734) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CRKLP461092MINT-8432551 MINT-8432380 MINT-8432470
    BCAR1P569452MINT-8432380
    FYNP062412MINT-8432517
    SEMA4BENSP000003322044STRING: ENSP00000332204
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion IEA--
    GO:0030308negative regulation of cell growth IDA11447234
    GO:0030522intracellular receptor signaling pathway NAS11447234
    GO:0042060wound healing IDA11447234

    DCBLD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DCBLD2 (DCBD2)

    Search CenterWatch for drugs/clinical trials and news about DCBLD2 / DCBD2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DCBLD2 gene: 
    NM_080927.3  

    Unigene Cluster for DCBLD2:

    Discoidin, CUB and LCCL domain containing 2
    Hs.203691  [show with all ESTs]
    Unigene Representative Sequence: NM_080927
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000326840(uc003dtd.3 uc003dte.3 uc003dtf.1) ENST00000326857
    ENST00000496736 ENST00000494614 ENST00000479144 ENST00000470393 ENST00000460008
    ENST00000469648 ENST00000486004 ENST00000449482
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DCBLD2
    8/123 QIAGEN miScript miRNA Assays for microRNAs that regulate DCBLD2 (see all 123):
    hsa-miR-579 hsa-miR-300 hsa-miR-106a hsa-miR-1224-3p hsa-miR-199a-3p hsa-miR-15a hsa-miR-128 hsa-miR-1260b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCBLD2
    Sirion Biotech Customized lentivirus for stable overexpression of DCBLD2 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DCBLD2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DCBLD2

    Additional mRNA sequence: 

    AB073146.1 AF104313.1 AF387547.1 AK001362.1 AK056350.1 AK302649.1 BC007117.1 BC016815.1 
    BC029658.1 BX647140.1 D29810.1 

    12 DOTS entries:

    DT.100028579  DT.102833519  DT.95179834  DT.416993  DT.75123629  DT.92056600  DT.99974173  DT.102833520 
    DT.120914541  DT.86848429  DT.40257901  DT.97765306 

    24/278 AceView cDNA sequences (see all 278):

    AW138866 BU753325 AW583777 AA128681 AI654989 AI695876 BU687616 AF387547 
    BU171889 AI379718 AA341724 NM_080927 AA304469 BU741198 BM450083 AA885289 
    AA622938 BU634176 BU628593 CB044538 N71977 AI242761 AI750960 R53270 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for DCBLD2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15a · 15b ^ 16a · 16b · 16c
    SP1:                                                                                      -     -           -                           
    SP2:                                                                                      -     -                                       
    SP3:                                                                                                                                    
    SP4:                                                                                                        -                           


    ECgene alternative splicing isoforms for DCBLD2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DCBLD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACTGTAGTC
    DCBLD2 Expression
    About this image


    See DCBLD2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DCBLD2

    SOURCE GeneReport for Unigene cluster: Hs.203691

    UniProtKB/Swiss-Prot: DCBD2_HUMAN, Q96PD2
    Tissue specificity: Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle
    cells

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCBLD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for DCBLD2 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dcbld21 , 5 discoidin, CUB and LCCL domain containing 21, 5 85.61(n)1
    85.14(a)1
      16 (34.52 cM)5
    733791  NM_028523.31  NP_082799.21 
     584084435 
    chicken
    (Gallus gallus)
    Aves DCBLD21 discoidin, CUB and LCCL domain containing 2 75.26(n)
    77.31(a)
      418379  NM_001030783.1  NP_001025954.1 
    lizard
    (Anolis carolinensis)
    Reptilia DCBLD26
    discoidin, CUB and LCCL domain containing 2
    74(a)
    1 ↔ 1
    3(174563295-174606959)
    zebrafish
    (Danio rerio)
    Actinopterygii dcbld26
    discoidin, CUB and LCCL domain containing 2
    54(a)
    1 ↔ 1
    9(31043383-31087487)


    ENSEMBL Gene Tree for DCBLD2 (if available)
    TreeFam Gene Tree for DCBLD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DCBLD2 gene
    DCBLD12  EDIL32  NRP12  MFGE82  F82  RS12  NRP22  F52  
    6 SIMAP similar genes for DCBLD2 using alignment to 3 protein entries:     DCBD2_HUMAN (see all proteins):
    CNTNAP2    TLL1    DCBLD1    RS1    C1R    NRP1

    DCBLD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2219 SNPs in DCBLD2 are shown (see all 2219)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs356658661,2
    C--95911636(+) TTTTT-/T/TT  
            
    AGGAG
    1 -- int11NA 2
    rs1511686091,2
    C--98515237(+) AAAAGC/TAGAGA 1 -- ut310--------
    rs1854329971,2
    --98515448(+) TTCTTC/TACTCG 1 -- ut310--------
    rs1401253441,2
    --98515457(+) CGAACC/TGTTTA 1 -- ut310--------
    rs88331,2
    C,F,A,H--98515569(+) ATTTAC/TAGCAT 1 -- ut3127Minor allele frequency- T:0.41MN NA NS EA WA 3216
    rs1155398861,2
    F--98515608(+) TATCTT/AAAACT 1 -- ut311Minor allele frequency- A:0.01WA 118
    rs1920707631,2
    --98515664(+) ATGAAA/TCCTGT 1 -- ut310--------
    rs1122966101,2
    C--98515826(+) TTTTCA/GGTTGT 1 -- ut312Minor allele frequency- G:0.03CSA WA 120
    rs563691371,2
    C--98515881(+) GTAGT-/AAAAAAA 1 -- ut310--------
    rs76506461,2
    C,F,H--98515897(+) AAAAAC/AAAATA 1 -- ut31 trp33Minor allele frequency- A:0.50NA CSA 6

    HapMap Linkage Disequilibrium report for DCBLD2 (98514785 - 98620533 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for DCBLD2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2606873CNV Deletion19546169
    nsv509842CNV Loss20534489
    nsv877214CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for DCBLD2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608698    OMIM disorders: --

    5 diseases for DCBLD2:    About MalaCards
    arteriosclerosis    endotheliitis    asthma    lung cancer
    gastric cancer


    DCBLD2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): DCBLD2
    Human Genome Epidemiology (HuGE) Navigator: DCBLD2 (2 documents)

    Export disorders for DCBLD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DCBLD2 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with DCBLD2)
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    1. ESDN, a novel neuropilin-like membrane protein cloned from vascular cells with the longest secretory signal sequence among eukaryotes, is up-regulated after vascular injury. (PubMed id 11447234)1, 2, 3, 9 Kobuke K.... Tashiro K. (2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Significant up-regulation of a novel gene, CLCP1, in a highly metastatic lung cancer subline as well as in lung cancers in vivo. (PubMed id 11973641)1, 2 Koshikawa K.... Takahashi T. (2002)
    5. ESDN is a marker of vascular remodeling and regulator of cell proliferation in graft arteriosclerosis. (PubMed id 17697260)1, 9 Sadeghi M.M....Rodriguez E.R. (2007)
    6. Endothelial and smooth muscle-derived neuropilin-like protein regulates platelet-derived growth factor signaling in human vascular s mooth muscle cells by modulating receptor ubiquitination. (PubMed id 19696027)1, 9 Guo X....Sadeghi M.M. (2009)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    8. DCBLD2 gene variations correlate with nasal polyposis in Korean asthma patients. (PubMed id 22261696)1 Pasaje C.F....Shin H.D. (2012)
    9. Potential association of DCBLD2 polymorphisms with fal l rates of FEV(1) by aspirin provocation in Korean asthmatics. (PubMed id 22468095)1 Park T.J....Shin H.D. (2012)
    10. Expression of AP-2a, AP-2g and ESDN in primary melanom as: correlation with histopathological features and potential prognostic value. (PubMed id 23036739)1 Osella-Abate S....Taverna D. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 131566 HGNC: 24627 AceView: DCBLD2 Ensembl:ENSG00000057019 euGenes: HUgn131566
    ECgene: DCBLD2 H-InvDB: DCBLD2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DCBLD2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for DCBLD2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DCBLD2 gene:
    Search GeneIP for patents involving DCBLD2

    GeneCards and IP:
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