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Aliases for DCBLD1 Gene

Aliases for DCBLD1 Gene

  • Discoidin, CUB And LCCL Domain Containing 1 2 3
  • Discoidin, CUB And LCCL Domain-Containing Protein 1 3
  • DJ94G16.1 3

External Ids for DCBLD1 Gene

Summaries for DCBLD1 Gene

GeneCards Summary for DCBLD1 Gene

DCBLD1 (Discoidin, CUB And LCCL Domain Containing 1) is a Protein Coding gene. An important paralog of this gene is NRP2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DCBLD1 Gene

Genomics for DCBLD1 Gene

Genomic Location for DCBLD1 Gene

Start:
117,453,817 bp from pter
End:
117,569,858 bp from pter
Size:
116,042 bases
Orientation:
Plus strand

Genomic View for DCBLD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DCBLD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DCBLD1 Gene

Regulatory Elements for DCBLD1 Gene

Proteins for DCBLD1 Gene

  • Protein details for DCBLD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8Z6-DCBD1_HUMAN
    Recommended name:
    Discoidin, CUB and LCCL domain-containing protein 1
    Protein Accession:
    Q8N8Z6
    Secondary Accessions:
    • Q5H992
    • Q8IYK5
    • Q8N7L9
    • Q96NH2

    Protein attributes for DCBLD1 Gene

    Size:
    715 amino acids
    Molecular mass:
    77920 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04663.1; Type=Frameshift; Positions=483; Evidence={ECO:0000305}; Sequence=BAC05258.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for DCBLD1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DCBLD1 Gene

Proteomics data for DCBLD1 Gene at MOPED

Post-translational modifications for DCBLD1 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn64, Asn124, Asn277, Asn351, Asn418, and Asn455

Other Protein References for DCBLD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for DCBLD1 Gene

Domains for DCBLD1 Gene

UniProtKB/Swiss-Prot:

DCBD1_HUMAN
Domain:
  • Contains 1 CUB domain.:
    • Q8N8Z6
  • Contains 1 F5/8 type C domain.:
    • Q8N8Z6
  • Contains 1 LCCL domain.:
    • Q8N8Z6
genes like me logo Genes that share domains with DCBLD1: view

No data available for Gene Families for DCBLD1 Gene

Function for DCBLD1 Gene

Gene Ontology (GO) - Molecular Function for DCBLD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070492 oligosaccharide binding IBA --
genes like me logo Genes that share ontologies with DCBLD1: view

miRNA for DCBLD1 Gene

miRTarBase miRNAs that target DCBLD1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for DCBLD1 Gene

Localization for DCBLD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DCBLD1 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DCBLD1 Gene COMPARTMENTS Subcellular localization image for DCBLD1 gene
Compartment Confidence
plasma membrane 3
peroxisome 2
endoplasmic reticulum 1
extracellular 1

Gene Ontology (GO) - Cellular Components for DCBLD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with DCBLD1: view

Pathways for DCBLD1 Gene

SuperPathways for DCBLD1 Gene

No Data Available

Interacting Proteins for DCBLD1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000296955%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000300289%0d%0a
Selected Interacting proteins: Q8N8Z6-DCBD1_HUMAN ENSP00000296955 for DCBLD1 Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for DCBLD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007155 cell adhesion --
genes like me logo Genes that share ontologies with DCBLD1: view

No data available for Pathways by source for DCBLD1 Gene

Compounds for DCBLD1 Gene

(2) PharmGKB related drug/compound annotations for DCBLD1 Gene

Drug/compound Annotation
cisplatin CA
irinotecan CA
genes like me logo Genes that share compounds with DCBLD1: view

Transcripts for DCBLD1 Gene

Unigene Clusters for DCBLD1 Gene

Discoidin, CUB and LCCL domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DCBLD1 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b
SP1: - - -
SP2: -
SP3:
SP4:
SP5:

Relevant External Links for DCBLD1 Gene

GeneLoc Exon Structure for
DCBLD1
ECgene alternative splicing isoforms for
DCBLD1

Expression for DCBLD1 Gene

mRNA expression in normal human tissues for DCBLD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DCBLD1 Gene

SOURCE GeneReport for Unigene cluster for DCBLD1 Gene Hs.658304

genes like me logo Genes that share expressions with DCBLD1: view

Orthologs for DCBLD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for DCBLD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia DCBLD1 36
  • 99.73 (n)
  • 100 (a)
DCBLD1 37
  • 73 (a)
OneToOne
cow
(Bos Taurus)
Mammalia DCBLD1 36
  • 87.71 (n)
  • 86.78 (a)
DCBLD1 37
  • 62 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DCBLD1 37
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dcbld1 36
  • 84.38 (n)
  • 82.7 (a)
Dcbld1 16
Dcbld1 37
  • 54 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DCBLD1 37
  • 48 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DCBLD1 37
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dcbld1 36
  • 83.12 (n)
  • 83.75 (a)
chicken
(Gallus gallus)
Aves DCBLD1 36
  • 71.45 (n)
  • 69.16 (a)
DCBLD1 37
  • 45 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia DCBLD1 37
  • 46 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia dcbld1 36
  • 62.85 (n)
  • 57.71 (a)
zebrafish
(Danio rerio)
Actinopterygii dcbld1 37
  • 32 (a)
OneToOne
Species with no ortholog for DCBLD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DCBLD1 Gene

ENSEMBL:
Gene Tree for DCBLD1 (if available)
TreeFam:
Gene Tree for DCBLD1 (if available)

Paralogs for DCBLD1 Gene

Paralogs for DCBLD1 Gene

Selected SIMAP similar genes for DCBLD1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with DCBLD1: view

Variants for DCBLD1 Gene

Sequence variations from dbSNP and Humsavar for DCBLD1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs8088 -- 117,549,729(+) GGGAA(A/G)TGGTT intron-variant, utr-variant-3-prime, nc-transcript-variant
rs176803 -- 117,537,637(-) AAAAG(A/G)AAAAA intron-variant
rs210608 -- 117,510,154(-) AGCAA(A/G)ATGAT intron-variant
rs210609 -- 117,512,198(-) TTCAC(A/T)ACCCA intron-variant
rs210610 -- 117,513,281(-) GTTTC(A/G)GGCTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DCBLD1 Gene

Variant ID Type Subtype PubMed ID
nsv507356 CNV Insertion 20534489
esv2668460 CNV Deletion 23128226
esv2732613 CNV Deletion 23290073

Relevant External Links for DCBLD1 Gene

HapMap Linkage Disequilibrium report
DCBLD1

Disorders for DCBLD1 Gene

Relevant External Links for DCBLD1

Genetic Association Database (GAD)
DCBLD1
Human Genome Epidemiology (HuGE) Navigator
DCBLD1
genes like me logo Genes that share disorders with DCBLD1: view

No data available for UniProtKB/Swiss-Prot for DCBLD1 Gene

Publications for DCBLD1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. ERp57 is essential for efficient folding of glycoproteins sharing common structural domains. (PMID: 17170699) Jessop C.E. … Bulleid N.J. (EMBO J. 2007) 3

Products for DCBLD1 Gene

Sources for DCBLD1 Gene

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