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DCAKD Gene

protein-coding   GIFtS: 54
GCID: GC17M043100

Dephospho-CoA Kinase Domain Containing

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Dephospho-CoA Kinase Domain Containing1 2
Dephospho-CoA Kinase Domain-Containing Protein2
EC 2.7.1.248

External Ids:    HGNC: 262381   Entrez Gene: 798772   Ensembl: ENSG000001729927   UniProtKB: Q8WVC63   

Export aliases for DCAKD gene to outside databases

Previous GC identifers: GC17M040457 GC17M038864


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DCAKD Gene:
DCAKD (dephospho-CoA kinase domain containing) is a protein-coding gene. Diseases associated with DCAKD include pneumonia, and tuberculosis. GO annotations related to this gene include dephospho-CoA kinase activity.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the DCAKD gene promoter:
         c-Fos   AP-1   MAZR   Cart-1   AP-4   IRF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DCAKD promoter sequence
   Search Chromatin IP Primers for DCAKD

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DCAKD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.31   Ensembl cytogenetic band:  17q21.31   HGNC cytogenetic band: 17q21.31

DCAKD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCAKD gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M043100:  view genomic region     (about GC identifiers)

Start:
43,100,706 bp from pter      End:
43,138,473 bp from pter
Size:
37,768 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: DCAKD_HUMAN, Q8WVC6 (See protein sequence)
Recommended Name: Dephospho-CoA kinase domain-containing protein  
Size: 231 amino acids; 26550 Da
Secondary accessions: A8K3Z0 D3DX60 D3DX62 Q9BR71 Q9H5W1
Alternative splicing: 2 isoforms:  Q8WVC6-1   Q8WVC6-2   

Explore the universe of human proteins at neXtProt for DCAKD: NX_Q8WVC6

Explore proteomics data for DCAKD at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys67, Lys168, Lys186
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for DCAKD (Q8WVC6)
     DIPLLFE  LTGGIASGK 


    See DCAKD Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001122103.1  NP_001275583.1  NP_001275584.1  NP_079095.3  

    ENSEMBL proteins: 
     ENSP00000413483   ENSP00000341504   ENSP00000467913   ENSP00000468809   ENSP00000308515  

    DCAKD Human Recombinant Protein Products:

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    Novus Biologicals DCAKD Proteins
    Novus Biologicals DCAKD Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DCAKD

    DCAKD Antibody Products:

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    Search for Antibodies for DCAKD at Abcam
    Cloud-Clone Corp. Antibodies for DCAKD
    Search ThermoFisher Antibodies for DCAKD
    LSBio Antibodies in human, mouse, rat for DCAKD

    DCAKD Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for DCAKD
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for DCAKD
    Cloud-Clone Corp. CLIAs for DCAKD


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR001977 Depp_CoAkinase
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q8WVC6

    ProtoNet protein and cluster: Q8WVC6

    1 Blocks protein domain: IPB001977 Dephospho-CoA kinase

    UniProtKB/Swiss-Prot: DCAKD_HUMAN, Q8WVC6
    Similarity: Belongs to the CoaE family
    Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain


    DCAKD for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Number (IUBMB): EC 2.7.1.242

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004140dephospho-CoA kinase activity IEA--
    GO:0005524ATP binding IEA--
         
    DCAKD for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DCAKD
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DCAKD

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DCAKD
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DCAKD

    miRNA
    Products:
        
    miRTarBase miRNAs that target DCAKD:
    hsa-mir-335-5p (MIRT018751), hsa-mir-1 (MIRT024049)

    Block miRNA regulation of human, mouse, rat DCAKD using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate DCAKD:
    hsa-miR-124 hsa-miR-143 hsa-miR-506
    SwitchGear 3'UTR luciferase reporter plasmidDCAKD 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for DCAKD
    Predesigned siRNA for gene silencing in human, mouse, rat DCAKD

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for DCAKD

    Clone
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    OriGene clones in human, mouse for DCAKD (see all 12)
    OriGene ORF clones in mouse, rat for DCAKD
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): DCAKD (NM_001128631)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DCAKD
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCAKD

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for DCAKD 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCAKD


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    mitochondrion2
    endoplasmic reticulum1
    extracellular1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--

    DCAKD for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for DCAKD About    
    See pathways by source

    SuperPathContained pathways About
    1Integrated Breast Cancer Pathway
    Integrated Breast Cancer Pathway


    1 BioSystems Pathway for DCAKD
        Integrated Breast Cancer Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DCAKD
    Interactions:

        Search GeneGlobe Interaction Network for DCAKD

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for DCAKD (Q8WVC63 ENSP000003415044) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CDC6Q997413, ENSP000002097284I2D: score=4 STRING: ENSP00000209728
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    ARPC2O151443I2D: score=2 
    ABHD14BQ96IU43I2D: score=1 
    ATP6V1B2P212813I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015937coenzyme A biosynthetic process IEA--

    DCAKD for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DCAKD



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for DCAKD gene (4 alternative transcripts): 
    NM_001128631.2  NM_001288654.1  NM_001288655.1  NM_024819.5  

    Unigene Cluster for DCAKD:

    Dephospho-CoA kinase domain containing
    Hs.463148  [show with all ESTs]
    Unigene Representative Sequence: NM_024819
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000452796(uc002ihx.2 uc010daa.1) ENST00000342350(uc010dab.1)
    ENST00000588499 ENST00000593094 ENST00000592902 ENST00000588295 ENST00000310604(uc002ihy.3)

    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat DCAKD using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate DCAKD:
    hsa-miR-124 hsa-miR-143 hsa-miR-506
    SwitchGear 3'UTR luciferase reporter plasmidDCAKD 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for DCAKD
    Predesigned siRNA for gene silencing in human, mouse, rat DCAKD
    Clone
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    OriGene clones in human, mouse for DCAKD (see all 12)
    OriGene ORF clones in mouse, rat for DCAKD
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): DCAKD (NM_001128631)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DCAKD
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCAKD
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for DCAKD
    OriGene qSTAR qPCR primer pairs in human, mouse for DCAKD
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DCAKD
      QuantiTect SYBR Green Assays in human, mouse, rat DCAKD
      QuantiFast Probe-based Assays in human, mouse, rat DCAKD

    Additional mRNA sequence: 

    AK026608.1 AK290755.1 BC006472.1 BC006546.2 BC018132.2 BC033299.1 

    11 DOTS entries:

    DT.446140  DT.95102987  DT.92423080  DT.100782259  DT.97805778  DT.100825424  DT.120953438  DT.40275492 
    DT.92423083  DT.91688209  DT.91986485 

    Selected AceView cDNA sequences (see all 93):

    BX342453 BC018132 BC033299 CK819136 BM127765 BI093355 BM128029 AK026608 
    BM142189 BM141882 BX109987 W65474 BU168354 BX333265 BC006546 CD671452 
    BX406708 CK819137 CD388079 AA306497 BX401308 BE907883 AI939621 BF347569 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for DCAKD (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c
    SP1:                          -     -                 -                           
    SP2:                                -                 -                           
    SP3:              -     -     -     -                 -                           
    SP4:                          -     -                                             
    SP5:                                                  -                           


    ECgene alternative splicing isoforms for DCAKD

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DCAKD expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCCCAGGAA
    DCAKD Expression
    About this image

    DCAKD Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DCAKD Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.463148
        Custom PCR Arrays for DCAKD
    Primer
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    OriGene qPCR primer pairs and template standards for DCAKD
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DCAKD
    QuantiTect SYBR Green Assays in human, mouse, rat DCAKD
    QuantiFast Probe-based Assays in human, mouse, rat DCAKD
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCAKD

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DCAKD gene from Selected species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dcakd1 , 5 dephospho-CoA kinase domain containing1, 5 86.09(n)1
    91.74(a)1
      11 (66.71 cM)5
    680871  NM_026551.31  NP_080827.21 
     1029940475 
    chicken
    (Gallus gallus)
    Aves DCAKD1 dephospho-CoA kinase domain containing 67.13(n)
    62.67(a)
      419967  XM_004948492.1  XP_004948549.1 
    lizard
    (Anolis carolinensis)
    Reptilia DCAKD6
    dephospho-CoA kinase domain containing
    60(a)
    1 ↔ 1
    6(64753584-64765545)
    African clawed frog
    (Xenopus laevis)
    Amphibia CB206827.12   -- 74.3(n)    CB206827.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dcakd1 dephospho-CoA kinase domain containing 61.42(n)
    56.94(a)
      751733  NM_001045443.1  NP_001038908.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Dpck1 Dephospho-CoA kinase 55.19(n)
    46.11(a)
      40846  NM_141435.3  NP_649692.2 
    worm
    (Caenorhabditis elegans)
    Secernentea T05G5.51 T05G5.5 48.27(n)
    39.62(a)
      176375  NM_001268095.1  NP_001255024.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CAB5(YDR196C)4
    CAB51
    Probable dephospho-CoA kinase (DPCK) that catalyzes more4
    CAB51
    46.32(n)1
    41.78(a)1
      4(850999-850274)4
    8517771, 4  NP_010482.31  NP_010482.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ATCOAE1 ATCOAE 46.36(n)
    40.47(a)
      817294  NM_128309.3  NP_180318.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g03606001 Os01g0360600 50.09(n)
    45.99(a)
      4326028  NM_001049556.1  NP_001043021.1 


    ENSEMBL Gene Tree for DCAKD (if available)
    TreeFam Gene Tree for DCAKD (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DCAKD gene
    1 SIMAP similar gene for DCAKD using alignment to 2 protein entries:     DCAKD_HUMAN (see all proteins):
    COASY

    DCAKD for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DCAKD (see all 784)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs118716251,2
    C,F,H--43100329(+) CTAGAT/CTCAGC 2 -- int12Minor allele frequency- C:0.25NA WA 4
    rs620657831,2
    C--43100389(+) GCATCC/TGTCAC 2 -- int10--------
    rs72202121,2
    C,F,A,H--43100566(+) TCCCAC/GAAAGG 2 -- int17Minor allele frequency- G:0.20WA NA EA 366
    rs1477763351,2
    --43100663(+) GCTCCA/GGGAGG 2 -- int10--------
    rs125681,2
    C,F,H--43100831(-) CCTACT/GAGACT 2 -- ut31 ese323Minor allele frequency- G:0.25MN NS EA NA WA 2712
    rs3702833541,2
    C--43100994(+) aaaaa-/A/AAA 
            
    ggaag
    4 -- ut31 cds11NA 2
    rs620657841,2
    --43100996(+) AAAAGA/GAAGAA 2 -- ut310--------
    rs1410982731,2
    --43101023(+) AAAGGC/TATCCC 2 -- ut310--------
    rs1469639991,2
    --43101167(+) ACGTGA/GGGAGA 2 -- ut310--------
    rs1152289631,2
    C,F--43101268(+) GGCCTG/AGGCCT 2 -- ut311Minor allele frequency- A:0.02WA 118

    HapMap Linkage Disequilibrium report for DCAKD (43100706 - 43138473 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for DCAKD:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2438788CNV Deletion19546169
    esv2674469CNV Deletion23128226
    esv1217416CNV Deletion17803354
    nsv833457CNV Loss17160897
    nsv527788CNV Loss19592680
    nsv908289CNV Loss21882294

    Human Gene Mutation Database (HGMD): DCAKD
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DCAKD
    DNA2.0 Custom Variant and Variant Library Synthesis for DCAKD

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    4 diseases for DCAKD:    
    About MalaCards
    pneumonia    tuberculosis    malaria    breast cancer


    DCAKD for disorders           About GeneDecksing

    Genetic Association Database (GAD): DCAKD
    Human Genome Epidemiology (HuGE) Navigator: DCAKD (2 documents)

    Export disorders for DCAKD gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DCAKD gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with DCAKD)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79877 HGNC: 26238 AceView: FLJ22955 Ensembl:ENSG00000172992 euGenes: HUgn79877
    ECgene: DCAKD H-InvDB: DCAKD

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for DCAKD Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DCAKD gene:
    Search GeneIP for patents involving DCAKD

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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