Aliases for DCAF8 Gene
External Ids for DCAF8 Gene
Previous HGNC Symbols for DCAF8 Gene
Previous GeneCards Identifiers for DCAF8 Gene
This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009]
GeneCards Summary for DCAF8 Gene
DCAF8 (DDB1 And CUL4 Associated Factor 8) is a Protein Coding gene. Diseases associated with DCAF8 include giant axonal neuropathy 2, autosomal dominant and autosomal dominant charcot-marie-tooth disease type 2 with giant axons. An important paralog of this gene is DCAF8L1.
UniProtKB/Swiss-Prot for DCAF8 Gene
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.