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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DCAF8 Gene

protein-coding   GIFtS: 47
GCID: GC01M160185

DDB1 And CUL4 Associated Factor 8

(Previous name: WD repeat domain 42A)
(Previous symbol: WDR42A)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
DDB1 And CUL4 Associated Factor 81 2
WDR42A1 2 3
WD Repeat Domain 42A1 2
H3262 3
WD Repeat-Containing Protein 42A2 3
DDB1- And CUL4-Associated Factor 82

External Ids:    HGNC: 248911   Entrez Gene: 507172   Ensembl: ENSG000001327167   UniProtKB: Q5TAQ93   
ORGUL members:         
NONCODE14:n408146 n408149 n408148      

Export aliases for DCAF8 gene to outside databases

Previous GC identifers: GC01M158453 GC01M131542


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DCAF8 Gene:
This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular
complex. Multiple alternatively spliced transcript variants have been found for this gene. (provided by RefSeq,
Jul 2009)

GeneCards Summary for DCAF8 Gene: 
DCAF8 (DDB1 and CUL4 associated factor 8) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with DCAF8 include neural tube defects, and herpes simplex. GO annotations related to this gene include protein binding. An important paralog of this gene is ENSG00000258465.

UniProtKB/Swiss-Prot: DCAF8_HUMAN, Q5TAQ9
Function: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for DCAF8
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDCAF8 promoter sequence
   Search SABiosciences Chromatin IP Primers for DCAF8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DCAF8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q22-q23   Ensembl cytogenetic band:  1q23.2   HGNC cytogenetic band: 1q22-q23

DCAF8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCAF8 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M160185:  view genomic region     (about GC identifiers)

Start:
160,185,505 bp from pter      End:
160,232,350 bp from pter
Size:
46,846 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for DCAF8

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DCAF8_HUMAN, Q5TAQ9 (See protein sequence)
Recommended Name: DDB1- and CUL4-associated factor 8  
Size: 597 amino acids; 66852 Da
Subunit: Interacts with DDB1, CUL4A and CUL4B
Sequence caution: Sequence=AAA16607.1; Type=Frameshift; Positions=117, 123;
1 PDB 3D structure from and Proteopedia for DCAF8:
3I8E (3D)    
Secondary accessions: D3DVE6 Q12839 Q4QQI6 Q53F14 Q66K50 Q68CS7 Q96E00
Alternative splicing: 2 isoforms:  Q5TAQ9-1   Q5TAQ9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DCAF8: NX_Q5TAQ9

Explore proteomics data for DCAF8 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5TAQ9

  • DCAF8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DCAF8 Protein Expression
    REFSEQ proteins: NP_056541.2  
    ENSEMBL proteins: 
     ENSP00000357052   ENSP00000318227   ENSP00000357053   ENSP00000413688   ENSP00000411875  
     ENSP00000384118   ENSP00000409434  

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    Cloud-Clone Corp. Proteins for DCAF8 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0080008Cul4-RING ubiquitin ligase complex IDA16949367

    DCAF8 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    DCAF: DDB1 and CUL4 associated factors
    WDR: WD repeat domain containing

    3 InterPro protein domains:
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q5TAQ9

    ProtoNet protein and cluster: Q5TAQ9

    UniProtKB/Swiss-Prot: DCAF8_HUMAN, Q5TAQ9
    Similarity: Belongs to the WD repeat DCAF8 family
    Similarity: Contains 7 WD repeats


    DCAF8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DCAF8_HUMAN, Q5TAQ9
    Function: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16189514
         
    DCAF8 for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidDCAF8 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: DCAF8_HUMAN, Q5TAQ9
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DCAF8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/31 Interacting proteins for DCAF8 (Q5TAQ91, 2, 3 ENSP000003182274) via UniProtKB, MINT, STRING, and/or I2D (see all 31)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    MDFIQ997501, 2, 3, ENSP000002303214EBI-740686,EBI-724076 MINT-67377 I2D: score=5 STRING: ENSP00000230321
    KPNA1P522942, ENSP000003437014MINT-8328646 MINT-8328661 STRING: ENSP00000343701
    DDB1Q165313, ENSP000003017644I2D: score=2 STRING: ENSP00000301764
    GTPBP3Q969Y23, ENSP000003516444I2D: score=5 STRING: ENSP00000351644
    CUL4AQ136193, ENSP000003645894I2D: score=1 STRING: ENSP00000364589
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination IEA--

    DCAF8 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DCAF8

    Search CenterWatch for drugs/clinical trials and news about DCAF8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DCAF8 gene: 
    NM_015726.3  

    Unigene Cluster for DCAF8:

    DDB1 and CUL4 associated factor 8
    Hs.632447  [show with all ESTs]
    Unigene Representative Sequence: NR_028103
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368073(uc001fvn.2 uc009wth.2 uc001fvr.2) ENST00000326837(uc001fvo.2)
    ENST00000368074(uc010pjb.1 uc010pjc.1) ENST00000477163 ENST00000473382
    ENST00000476033 ENST00000461888 ENST00000490368 ENST00000497354 ENST00000481831
    ENST00000466253 ENST00000475733(uc001fvq.4 uc001fvp.4) ENST00000447377
    ENST00000495887 ENST00000440682 ENST00000407642 ENST00000419626
    miRNA
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    Additional mRNA sequence: 

    AK093176.1 AK223475.1 AK303188.1 AK312690.1 BC013107.1 BC080597.1 BC098245.1 BC098271.1 
    BC099709.1 BC099846.1 BC111063.1 CR749801.1 NR_028103.1 NR_028104.1 NR_028105.1 NR_028106.1 
    U06631.1 

    24/35 DOTS entries (see all 35):

    DT.92051950  DT.100717839  DT.100832270  DT.92437277  DT.95116105  DT.121410933  DT.92437269  DT.100743160 
    DT.75169508  DT.121410755  DT.87015963  DT.451997  DT.70104362  DT.100797017  DT.121410772  DT.100797018 
    DT.92437273  DT.95150538  DT.101982429  DT.95150536  DT.95359769  DT.121410851  DT.121410890  DT.40263756 

    8 AceView cDNA sequences:

    N45176 BF439213 BF060954 H59420 AA937174 N39328 H02445 H60073 

    GeneLoc Exon Structure

    5/29 Alternative Splicing Database (ASD) splice patterns (SP) for DCAF8 (see all 29)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c · 3d · 3e · 3f ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d · 6e · 6f · 6g · 6h · 6i ^
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                -     -     -     -     -     -     -                       -                                                               
    SP4:                                -     -     -     -     -     -     -     -                 -                                                               
    SP5:                                            -     -     -     -     -                       -                                                               

    ExUns: 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17a · 17b · 17c ^ 18a · 18b ^ 19a · 19b ^ 20a · 20b
    SP1:                                                  -     -     -     -     -     -                 -                           
    SP2:                                                  -           -           -     -                                             
    SP3:                                                                                                                              
    SP4:                                                                                                                              
    SP5:                                                                                                                              


    ECgene alternative splicing isoforms for DCAF8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DCAF8 expression in normal human tissues (normalized intensities)      DCAF8 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACTCTGGAA
    DCAF8 Expression
    About this image


    DCAF8 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/33 selected tissues (see all 33) fully expand
     
     Epithelium (Reproductive System)    fully expand to see all 5 entries
             vagina ; squamous epithelial cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Tonsil (Hematopoietic System)    fully expand to see all 3 entries
             tonsil ; squamous epithelial cells   

    See DCAF8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DCAF8

    SOURCE GeneReport for Unigene cluster: Hs.632447
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DCAF8 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dcaf81 , 5 DDB1 and CUL4 associated factor 81, 5 91.34(n)1
    96.43(a)1
      1 (79.54 cM)5
    981931  NM_153555.21  NP_705783.11 
     1721480155 
    chicken
    (Gallus gallus)
    Aves DCAF81 DDB1 and CUL4 associated factor 8 79.31(n)
    89.66(a)
      429253  XM_426809.3  XP_426809.3 
    lizard
    (Anolis carolinensis)
    Reptilia DCAF86
    Uncharacterized protein
    69(a)
    1 → many
    GL343637.1(289026-317879)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.254022 Xenopus laevis transcribed sequence with weak similarity more 83.6(n)    BJ037522.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000079241 DDB1- and CUL4-associated factor 8-like 65.87(n)
    66.27(a)
      100007924  XM_001346226.2  XP_001346262.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG80016
    --
    28(a)
    1 → many
    3L(1756159-1759208)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G351401 WD repeat-containing protein 42A 50.46(n)
    46.11(a)
      829666  NM_119680.5  NP_195240.2 
    rice
    (Oryza sativa)
    Liliopsida Os10g05445001 hypothetical protein 49.77(n)
    43.87(a)
      4349273  NM_001071736.1  NP_001065201.1 


    ENSEMBL Gene Tree for DCAF8 (if available)
    TreeFam Gene Tree for DCAF8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DCAF8 gene
    ENSG000002584652  DCAF8L22  WDTC12  DCAF62  DCAF8L12  
    8 SIMAP similar genes for DCAF8 using alignment to 8 protein entries:     DCAF8_HUMAN (see all proteins):
    PEX19    DCAF8L1    KIAA1651    DCAF8L2    FAM138A    FAM138B
    FAM138C    FAM138F

    DCAF8 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/851 SNPs in DCAF8 are shown (see all 851)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1388120171,2
    C--131541726(+) GCCCC-/TATCTT 3 -- ds50010--------
    rs1420612771,2
    --131541738(+) TGCTCG/TTCTGT 3 -- ds50010--------
    rs1131430731,2
    C--131541801(+) TGCAAA/C/GTAACT 3 -- ds50011CSA 1
    rs46562521,2
    C,F,H--131541900(+) GGGCTG/AGGAAA 3 -- ds500119Minor allele frequency- A:0.08NS EA NA 2362
    rs1921128581,2
    --131541956(+) ACTGAA/GCTAAA 3 -- ds50010--------
    rs1180143301,2
    C,F--131542150(+) CAGTCG/AGGAGA 3 -- ut31 nc-transcript-variant1Minor allele frequency- A:0.02EA 120
    rs1462603781,2
    C--131542172(+) ACTGGA/GAGAAA 3 -- ut31 nc-transcript-variant0--------
    rs591024011,2
    C--131542276(+) CCTCAG/AGGAGT 3 -- ut31 nc-transcript-variant3Minor allele frequency- A:0.03WA EA 240
    rs1849397091,2
    --131542324(+) GAAAAA/GGGGCA 3 -- ut31 nc-transcript-variant0--------
    rs2002277751,2
    --131542331(+) GGCAG-/GAG   
      GAAGAA
    GTATC
    3 -- cds1 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for DCAF8 (160185505 - 160232350 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for DCAF8:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2664173CNV Deletion23128226
    nsv3210CNV Loss18451855

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing DCAF8
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for DCAF8:    About MalaCards
    neural tube defects    herpes simplex


    DCAF8 for disorders           About GeneDecksing


    Export disorders for DCAF8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DCAF8 gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with DCAF8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1, 2 Weimann M.... Stelzl U. (2013)
    2. A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. (PubMed id 16949367)1, 2 Jin J.... Walter J.C. (2006)
    3. Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23. (PubMed id 11401431)1, 3 Doudney K....Stanier P. (2001)
    4. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    5. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    6. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    7. Characterization of nuclear import and export signals determining the subcellular localization of WD repeat-containing protein 42A (WD R42A). (PubMed id 22500989)1 Wu F....Zheng C. (2012)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 50717 HGNC: 24891 AceView: WDR42A Ensembl:ENSG00000132716 euGenes: HUgn50717
    ECgene: DCAF8 H-InvDB: DCAF8

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DCAF8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DCAF8 gene:
    Search GeneIP for patents involving DCAF8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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