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DCAF4 Gene

protein-coding   GIFtS: 46
GCID: GC14P073393

DDB1 And CUL4 Associated Factor 4

(Previous names: WD repeat domain 21, WD repeat domain 21A)
(Previous symbols: WDR21, WDR21A)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DDB1 And CUL4 Associated Factor 41 2     WD Repeat-Containing Protein 21A2 3
WDR211 2 3     WD Repeat Domain 211
WDR21A1 2 3     DDB1- And CUL4-Associated Factor 42
WD Repeat Domain 21A1 2     

External Ids:    HGNC: 202291   Entrez Gene: 260942   Ensembl: ENSG000001195997   UniProtKB: Q8WV163   

Export aliases for DCAF4 gene to outside databases

Previous GC identifers: GC14P072464 GC14P053559


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for DCAF4 Gene:
This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular
complex. Multiple alternatively spliced transcript variants have been found for this gene. (provided by RefSeq,
Jul 2009)

GeneCards Summary for DCAF4 Gene:
DCAF4 (DDB1 and CUL4 associated factor 4) is a protein-coding gene. An important paralog of this gene is DCAF4L1.

UniProtKB/Swiss-Prot: DCAF4_HUMAN, Q8WV16
Function: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NT_026437.13  NC_018925.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for DCAF4
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDCAF4 promoter sequence
   Search Chromatin IP Primers for DCAF4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DCAF4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q24.3   Ensembl cytogenetic band:  14q24.2   HGNC cytogenetic band: 14q24.3

DCAF4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCAF4 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P073393:  view genomic region     (about GC identifiers)

Start:
73,393,040 bp from pter      End:
73,426,411 bp from pter
Size:
33,372 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: DCAF4_HUMAN, Q8WV16 (See protein sequence)
Recommended Name: DDB1- and CUL4-associated factor 4  
Size: 495 amino acids; 55694 Da
Subunit: Interacts with DDB1 and CUL4A
1 PDB 3D structure from and Proteopedia for DCAF4:
3I8C (3D)    
Secondary accessions: B4DUT6 G3V522 Q86U31 Q8IV10 Q96K22 Q9Y4P5
Alternative splicing: 5 isoforms:  Q8WV16-1   Q8WV16-2   Q8WV16-3   Q8WV16-4   Q8WV16-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DCAF4: NX_Q8WV16

Explore proteomics data for DCAF4 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys460
  • Modification sites at PhosphoSitePlus

  • See DCAF4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001156980.1  NP_001156981.1  NP_056419.2  NP_851937.1  NP_851938.2  

    ENSEMBL proteins: 
     ENSP00000351147   ENSP00000345176   ENSP00000422270   ENSP00000377781   ENSP00000426178  
     ENSP00000452131   ENSP00000451186  

    DCAF4 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for DCAF4

     
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    antibodies-online proteins for DCAF4 (3 products) 

     
    antibodies-online peptides for DCAF4

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    antibodies-online antibodies for DCAF4 (18 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DCAF: DDB1 and CUL4 associated factors
    WDR: WD repeat domain containing

    3 InterPro protein domains:
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q8WV16

    ProtoNet protein and cluster: Q8WV16

    UniProtKB/Swiss-Prot: DCAF4_HUMAN, Q8WV16
    Similarity: Contains 2 WD repeats


    Find genes that share domains with DCAF4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DCAF4_HUMAN, Q8WV16
    Function: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with DCAF4           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for DCAF4

    miRNA
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    miRTarBase miRNAs that target DCAF4:
    hsa-mir-24-3p (MIRT030411)

    Block miRNA regulation of human, mouse, rat DCAF4 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate DCAF4:
    hsa-miR-558 hsa-miR-3202 hsa-miR-4263 hsa-miR-1299
    SwitchGear 3'UTR luciferase reporter plasmidDCAF4 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DCAF4

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCAF4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0080008Cul4-RING ubiquitin ligase complex IDA16949367

    Find genes that share ontologies with DCAF4           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    UniProtKB/Swiss-Prot: DCAF4_HUMAN, Q8WV16
    Pathway: Protein modification; protein ubiquitination

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DCAF4
    Interactions:

        Search GeneGlobe Interaction Network for DCAF4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    Selected Interacting proteins for DCAF4 (Q8WV163 ENSP000003511474) via UniProtKB, MINT, STRING, and/or I2D (see all 24)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPS5Q929053, ENSP000003505124I2D: score=1 STRING: ENSP00000350512
    COPS6Q7L5N13, ENSP000003041024I2D: score=1 STRING: ENSP00000304102
    DDB1Q165313, ENSP000003017644I2D: score=1 STRING: ENSP00000301764
    CUL4AQ136193, ENSP000003645894I2D: score=1 STRING: ENSP00000364589
    USP7Q930093, ENSP000003435354I2D: score=1 STRING: ENSP00000343535
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination IEA--

    Find genes that share ontologies with DCAF4           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DCAF4

    1 PharmGKB related drug/compound annotation for DCAF4 gene    About this table
    Drug/compound PharmGKB Annotation
    corticosteroidsCA  



    Find genes that share compounds with DCAF4           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DCAF4 gene (5 alternative transcripts): 
    NM_001163508.1  NM_001163509.1  NM_015604.3  NM_181340.2  NM_181341.2  

    Unigene Cluster for DCAF4:

    DDB1 and CUL4 associated factor 4
    Hs.331491  [show with all ESTs]
    Unigene Representative Sequence: AL080157
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000358377 ENST00000353777(uc001xni.3) ENST00000509320 ENST00000394234(uc001xnh.3)
    ENST00000509153 ENST00000555042(uc010ttr.2 uc001xnj.3 uc001xng.3 uc010tts.2 uc010ttt.2)
    ENST00000514191 ENST00000505361 ENST00000510612 ENST00000508412 ENST00000514486
    ENST00000553457(uc001xnk.3) ENST00000513337 ENST00000557203 ENST00000555992

    miRNA
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    4 qRT-PCR Assays for microRNAs that regulate DCAF4:
    hsa-miR-558 hsa-miR-3202 hsa-miR-4263 hsa-miR-1299
    SwitchGear 3'UTR luciferase reporter plasmidDCAF4 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DCAF4
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): DCAF4 (NM_015604)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DCAF4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCAF4
    Primer
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    OriGene qPCR primer pairs and template standards for DCAF4
    OriGene qSTAR qPCR primer pairs in human, mouse for DCAF4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DCAF4
      QuantiTect SYBR Green Assays in human, mouse, rat DCAF4
      QuantiFast Probe-based Assays in human, mouse, rat DCAF4

    Additional mRNA sequence: 

    AK027745.1 AK297571.1 AK297742.1 AK300786.1 AK315499.1 AL080157.1 BC018979.2 BC035901.1 
    BX161489.1 BX247962.1 

    11 DOTS entries:

    DT.412533  DT.97842484  DT.100791060  DT.100791058  DT.100791056  DT.100791062  DT.120755476  DT.65286008 
    DT.86859093  DT.91841531  DT.40302320 

    Selected AceView cDNA sequences (see all 119):

    C02546 BP351303 Z41584 NM_015604 BI915515 AW438829 BX283926 BM468150 
    BM129489 BC035901 AW167878 BF197939 BM824382 AW250072 BM988680 BM811013 
    BX247962 BM141687 BI963764 AI686444 BM761316 NM_181341 BE250235 BM973774 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for DCAF4 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18
    SP1:                                      -     -                                   -                                       
    SP2:              -                       -     -                                   -                                       
    SP3:                                                                                -                                       
    SP4:                                -     -     -     -                 -     -     -     -     -                           
    SP5:                                                                                                                        


    ECgene alternative splicing isoforms for DCAF4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DCAF4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTTTGTTCA
    DCAF4 Expression
    About this image

    DCAF4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DCAF4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.331491
        Custom PCR Arrays for DCAF4
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for DCAF4 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dcaf41 , 5 DDB1 and CUL4 associated factor 41, 5 83.44(n)1
    81.97(a)1
      12 (38.75 cM)5
    738281  NM_001165256.11  NP_001158728.11 
     835204665 
    chicken
    (Gallus gallus)
    Aves DCAF41 DDB1 and CUL4 associated factor 4 69.11(n)
    69.4(a)
      423253  XM_421173.4  XP_421173.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    59(a)
    1 → many
    1(38835561-38851154)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia dcaf41 DDB1 and CUL4 associated factor 4 59.18(n)
    52.48(a)
      100488467  XM_004917245.1  XP_004917302.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wdr212 WD repeat domain 21 73.66(n)   393674  AY423032.1 


    ENSEMBL Gene Tree for DCAF4 (if available)
    TreeFam Gene Tree for DCAF4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DCAF4 gene
    DCAF4L12  DCAF4L22  
    2 SIMAP similar genes for DCAF4 using alignment to 4 protein entries:     DCAF4_HUMAN (see all proteins):
    DCAF4L1    DCAF4L2

    Find genes that share paralogs with DCAF4           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DCAF4 (see all 884)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1486768751,2
    --73391060(+) CTCAGC/TAGATG 5 -- us2k10--------
    rs1855342591,2
    --73391100(+) CTGAGA/GTTGGA 5 -- us2k10--------
    rs1423385581,2
    C--73391132(+) GCCCAA/GCAAGC 5 -- us2k10--------
    rs1149581271,2
    C,F--73391263(+) TGGCCG/AGCTGC 5 -- us2k11Minor allele frequency- A:0.07WA 118
    rs1900220021,2
    --73391264(+) GGCCGC/GCTGCC 5 -- us2k10--------
    rs1427805431,2
    C--73391302(+) GCCAA-/CTCCTCCT 5 -- us2k10--------
    rs104838511,2
    C,F,H--73391340(+) CTCTTC/TAGTGG 5 -- us2k1 tfbs3105Minor allele frequency- T:0.06NS EA NA PA EU CA WA CSA 6855
    rs1508612171,2
    C--73391404(+) AATTCC/TGCCTC 5 -- us2k10--------
    rs1392433261,2
    C--73391478(+) AAGGAC/TTGTTG 5 -- us2k10--------
    rs1836256831,2
    --73391524(+) TCCACA/GATCTT 5 -- us2k10--------

    HapMap Linkage Disequilibrium report for DCAF4 (73393040 - 73426411 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for DCAF4:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv274200CNV Insertion20981092

    Human Gene Mutation Database (HGMD): DCAF4
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing DCAF4
    DNA2.0 Custom Variant and Variant Library Synthesis for DCAF4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with DCAF4           About GenesLikeMe


    Export disorders for DCAF4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DCAF4 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with DCAF4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. (PubMed id 16949367)1, 2 Jin J.... Walter J.C. (Mol. Cell 2006)
    2. Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. (PubMed id 16964240)1, 2 Angers S.... Zheng N. (Nature 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. Association between WDR21A polymorphisms and airway responsiveness to inhaled corticosteroids in asthmatic patients. (PubMed id 22366774)1 Cho S.H....Park C.S. (Pharmacogenet. Genomics 2012)
    7. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26094 HGNC: 20229 AceView: WDR21 Ensembl:ENSG00000119599 euGenes: HUgn26094
    ECgene: DCAF4 H-InvDB: DCAF4

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DCAF4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DCAF4 gene:
    Search GeneIP for patents involving DCAF4

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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