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DCAF13 Gene

protein-coding   GIFtS: 50
GCID: GC08P104426

DDB1 And CUL4 Associated Factor 13

(Previous name: WD repeats and SOF1 domain containing)
(Previous symbol: WDSOF1)
  Search for DCAF13
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
DDB1 And CUL4 Associated Factor 131 2
WDSOF11 2 3
WD Repeats And SOF1 Domain Containing1 2
WD Repeat And SOF Domain-Containing Protein 12 3
GM832
DDB1- And CUL4-Associated Factor 132

External Ids:    HGNC: 245351   Entrez Gene: 258792   Ensembl: ENSG000001649347   UniProtKB: Q9NV063   

Export aliases for DCAF13 gene to outside databases

Previous GC identifers: GC08P104500 GC08P099627


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DCAF13 Gene:
DCAF13 (DDB1 and CUL4 associated factor 13) is a protein-coding gene.

UniProtKB/Swiss-Prot: DCA13_HUMAN, Q9NV06
Function: Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for
CUL4-DDB1 E3 ubiquitin-protein ligase complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NC_018919.2  NT_008046.17  
Regulatory elements:
   Search for regulatory transcription factor binding sites for DCAF13
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DCAF13 promoter sequence
   Search Chromatin IP Primers for DCAF13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DCAF13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.3   Ensembl cytogenetic band:  8q22.3   HGNC cytogenetic band: 8q22.3

DCAF13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DCAF13 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P104426:  view genomic region     (about GC identifiers)

Start:
104,426,942 bp from pter      End:
104,455,681 bp from pter
Size:
28,740 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: DCA13_HUMAN, Q9NV06 (See protein sequence)
Recommended Name: DDB1- and CUL4-associated factor 13  
Size: 445 amino acids; 51402 Da
Subunit: Interacts with DDB1
Sequence caution: Sequence=AAH26067.2; Type=Erroneous initiation; Sequence=AAI01811.1; Type=Erroneous initiation;
Sequence=AAI12043.1; Type=Erroneous initiation; Sequence=BAB55377.1; Type=Erroneous initiation;
Sequence=BAC11163.1; Type=Erroneous initiation;
Secondary accessions: Q3MII9 Q8NCH8 Q8TC51 Q96JY7 Q9NZX3
Alternative splicing: 2 isoforms:  Q9NV06-1   Q9NV06-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DCAF13: NX_Q9NV06

Explore proteomics data for DCAF13 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys49, Lys56, Lys304, Lys359, Lys398
  • Modification sites at PhosphoSitePlus

  • See DCAF13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056235.4  
    ENSEMBL proteins: 
     ENSP00000297579   ENSP00000430645   ENSP00000430883   ENSP00000430411  

    DCAF13 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for DCAF13

     
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    Search eBioscience for ELISAs for DCAF13 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    DCAF: DDB1 and CUL4 associated factors
    WDR: WD repeat domain containing

    5 InterPro protein domains:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR007287 Sof1
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9NV06

    ProtoNet protein and cluster: Q9NV06

    UniProtKB/Swiss-Prot: DCA13_HUMAN, Q9NV06
    Similarity: Belongs to the WD repeat DCAF13/WDSOF1 family
    Similarity: Contains 7 WD repeats


    Find genes that share domains with DCAF13           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DCA13_HUMAN, Q9NV06
    Function: Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for
    CUL4-DDB1 E3 ubiquitin-protein ligase complex

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with DCAF13           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for DCAF13:
     Decreased circadian period len  Nuclear 40S maturation defects  Nucleolar pre-40S maturation d  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DCAF13
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    miRNA
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    miRTarBase miRNAs that target DCAF13:
    hsa-mir-149-5p (MIRT045689), hsa-mir-16-5p (MIRT031737)

    Block miRNA regulation of human, mouse, rat DCAF13 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate DCAF13:
    hsa-miR-7-1* hsa-miR-7-2* hsa-miR-630
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DCAF13
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCAF13

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for DCAF13 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCAF13


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DCA13_HUMAN, Q9NV06: Nucleus, nucleolus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion2
    nucleus2
    cytoskeleton1
    cytosol1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--
    GO:0030529ribonucleoprotein complex IEA--
    GO:0080008Cul4-RING ubiquitin ligase complex IDA16949367

    Find genes that share ontologies with DCAF13           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    UniProtKB/Swiss-Prot: DCA13_HUMAN, Q9NV06
    Pathway: Protein modification; protein ubiquitination

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DCAF13
    Interactions:

        Search GeneGlobe Interaction Network for DCAF13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for DCAF13 (Q9NV062, 3 ENSP000002975794) via UniProtKB, MINT, STRING, and/or I2D (see all 158)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing IEA--
    GO:0016567protein ubiquitination IEA--

    Find genes that share ontologies with DCAF13           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DCAF13 (DCA13)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for DCAF13 gene: 
    NM_015420.6  

    Unigene Cluster for DCAF13:

    DDB1 and CUL4 associated factor 13
    Hs.532265  [show with all ESTs]
    Unigene Representative Sequence: BC035190
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297579(uc003ylm.1 uc003yln.3) ENST00000521716 ENST00000521971
    ENST00000521999 ENST00000519682 ENST00000518554
    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate DCAF13:
    hsa-miR-7-1* hsa-miR-7-2* hsa-miR-630
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DCAF13
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: DCAF13 (NM_015420)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DCAF13
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DCAF13
    Primer
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    OriGene qPCR primer pairs and template standards for DCAF13
    OriGene qSTAR qPCR primer pairs in human, mouse for DCAF13
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DCAF13
      QuantiTect SYBR Green Assays in human, mouse, rat DCAF13
      QuantiFast Probe-based Assays in human, mouse, rat DCAF13

    Additional mRNA sequence: 

    AK001874.1 AK027799.1 AK074725.1 BC026067.1 BC035190.1 BC101810.1 BC107790.1 BC112042.1 

    15 DOTS entries:

    DT.452242  DT.100034321  DT.100042830  DT.121479176  DT.100888887  DT.100774157  DT.87007203  DT.95254659 
    DT.121479285  DT.309789  DT.121022384  DT.95204449  DT.97760546  DT.100717942  DT.121479210 

    Selected AceView cDNA sequences (see all 144):

    BG387958 AA831138 AA143048 CA429438 CR622604 BE552096 BQ028433 AI371514 
    AI921627 AW069891 BQ771897 BE891130 BQ228646 BI793181 BQ775427 CR620911 
    BU191835 AW074107 CB163488 AU133044 AK001874 BI793318 AI990615 BQ229363 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for DCAF13 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11
    SP1:                                                                                                      
    SP2:                                                                                                      
    SP3:                          -                                                                           
    SP4:                          -                                                                           
    SP5:              -     -     -     -     -                                                               


    ECgene alternative splicing isoforms for DCAF13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DCAF13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    DCAF13 Expression
    About this image

    DCAF13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DCAF13 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.532265
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DCAF13

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DCAF13 gene from Selected species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dcaf131 , 5 DDB1 and CUL4 associated factor 131, 5 89.27(n)1
    93.1(a)1
      15 (15.42 cM)5
    2234991  NM_198606.21  NP_941008.21 
     391128745 
    chicken
    (Gallus gallus)
    Aves DCAF131 DDB1 and CUL4 associated factor 13 80.23(n)
    88.74(a)
      420263  NM_001030948.1  NP_001026119.1 
    lizard
    (Anolis carolinensis)
    Reptilia DCAF136
    DDB1 and CUL4 associated factor 13
    86(a)
    1 ↔ 1
    4(13646296-13681296)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC042261.12   -- 75.23(n)    BC042261.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC044155.12   -- 74.97(n)   393097  BC044155.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG72751 CG7275 57.47(n)
    58.62(a)
      39669  NM_140510.3  NP_648767.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK430.71 ZK430.7 54.26(n)
    49.88(a)
      173778  NM_062380.3  NP_494781.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SOF1(YLL011W)4
    SOF11
    Essential protein required for biogenesis of 40S (small) more4
    SOF11
    55.58(n)1
    48.27(a)1
      12(127523-128992)4
    8506491, 4  NP_013090.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G284501 AT4G28450 54.34(n)
    48.37(a)
      828962  NM_118987.7  NP_567810.5 
    rice
    (Oryza sativa)
    Liliopsida Os.12282 Oryza sativa (japonica cultivar-group) putative DKFZP564O more 73.52(n)    AK111838.1 


    ENSEMBL Gene Tree for DCAF13 (if available)
    TreeFam Gene Tree for DCAF13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DCAF13 gene

    Find genes that share paralogs with DCAF13           About GenesLikeMe


    3 Pseudogenes.org Pseudogenes for DCAF13
    PGOHUM00000247117 PGOHUM00000235510 PGOHUM00000233518


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for DCAF13 (see all 585)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs58936551,2
    C--104429571(+) AAAAAA/-GATCT 1 -- int1 trp31Minor allele frequency- -:0.00NA 2
    rs1882679051,2
    --104429591(+) TTGGCA/TGGGCG 1 -- int10--------
    rs1448341911,2
    --104429596(+) TGGGCC/GTGGTG 1 -- int10--------
    rs1922239221,2
    --104429644(+) ACGGGC/TGGATC 1 -- int10--------
    rs1831548321,2
    --104429648(+) GCGGAC/TCACGA 1 -- int10--------
    rs30982401,2
    C,F,A--104429824(-) GACGCG/AATCTC 1 -- int17Minor allele frequency- A:0.38NA WA CSA 13
    rs2009876011,2
    C--104429889(-) ATGTTC/TTTTTT 1 -- int10--------
    rs1460513711,2
    --104429947(+) CTGCTC/TAAAAA 1 -- int10--------
    rs1400325451,2
    --104429991(+) AGACTA/GCTATA 1 -- int10--------
    rs732879481,2
    C,F--104430043(+) AAAAGG/CTGTTT 1 -- int11Minor allele frequency- C:0.50WA 2

    HapMap Linkage Disequilibrium report for DCAF13 (104426942 - 104455681 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for DCAF13: --
    Human Gene Mutation Database (HGMD): DCAF13
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DCAF13
    DNA2.0 Custom Variant and Variant Library Synthesis for DCAF13

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with DCAF13           About GenesLikeMe

    Genetic Association Database (GAD): DCAF13
    Human Genome Epidemiology (HuGE) Navigator: DCAF13 (1 document)

    Export disorders for DCAF13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DCAF13 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with DCAF13)
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    1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    2. Identification of non-synonymous polymorphisms in the WDSOF1 gene as novel susceptibility markers for low bone mineral density in Japanese postmenopausal women. (PubMed id 20601284)1, 4 Urano T....Inoue S. (Bone 2010)
    3. A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. (PubMed id 16949367)1, 2 Jin J.... Walter J.C. (Mol. Cell 2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    10. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25879 HGNC: 24535 AceView: DKFZP564O0463 Ensembl:ENSG00000164934 euGenes: HUgn25879
    ECgene: DCAF13 H-InvDB: DCAF13

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DCAF13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DCAF13 gene:
    Search GeneIP for patents involving DCAF13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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