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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DBNL Gene

protein-coding   GIFtS: 53
GCID: GC07P044084

drebrin-like

 Explore 2 diseases affiliated with
DBNL via our new
 Human Malady Compendium 
Biological research products
for DBNL
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Drebrin-Like1     ABP12
HIP-551 2 3     Drebrin-F3
SH3P71 2 3     Drebrin-Like Protein2
Cervical Mucin-Associated Protein2 3     Src Homology 3 Domain-Containing Protein HIP-552
Cervical SH3P72 3     CMAP3
HPK1-Interacting Protein Of 55 KDa2 3     Drebrin-F3
SH3 Domain-Containing Protein 72 3     

External Ids:    HGNC: 26961   Entrez Gene: 289882   Ensembl: ENSG000001362797   OMIM: 6101065   UniProtKB: Q9UJU63   

Export aliases for DBNL gene to outside databases

Previous GC identifers: GC07U990153 GC07P043857 GC07P044050 GC07P043969


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: DBNL_HUMAN, Q9UJU6
Function: Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in
leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic
function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and
the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin
polymerization, capping or bundling. Does not bind G-actin

Gene Wiki entry for DBNL (Drebrin-like)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DBNL gene promoter:
         Pax-5   AP-1   HTF   ATF-2   CUTL1   c-Jun   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): DBNL promoter sequence
   Search SABiosciences Chromatin IP Primers for DBNL

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DBNL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p13   Ensembl cytogenetic band:  7p13   HGNC cytogenetic band: 7p13

DBNL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DBNL gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P044084:  view genomic region     (about GC identifiers)

Start:
44,084,232 bp from pter      End:
44,109,055 bp from pter
Size:
24,824 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 44,123,733-44,140,805     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DBNL_HUMAN, Q9UJU6 (See protein sequence)
Recommended Name: Drebrin-like protein  
Size: 430 amino acids; 48207 Da
Subunit: Interacts with SHANK2 and SHANK3 (By similarity). Interacts with FGD1, dynamin, MAP4K1 and PRAM1. Interacts
with ANKRD54 (By similarity)
Subcellular location: Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note=Cortical cytoskeleton. Associates
with lamellipodial actin
1 PDB 3D structure from and Proteopedia for DBNL:
1X67 (3D)    
Secondary accessions: A4D2I9 P84070 Q6IAI8 Q96F30 Q96K74 Q9HBN8 Q9NR72
Alternative splicing: 3 isoforms:  Q9UJU6-1   Q9UJU6-2   Q9UJU6-3   (No experimental confirmation available. Contains a phosphoserine at position 232)

Explore the universe of human proteins at neXtProt for DBNL: NX_Q9UJU6

Post-translational modifications:

  • Degraded by caspases during apoptosis1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UJU6

  • DBNL Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001014436.1  NP_001116428.1  NP_054782.2  

    ENSEMBL proteins: 
     ENSP00000392113   ENSP00000411701   ENSP00000416421   ENSP00000403372   ENSP00000415173  
     ENSP00000418006   ENSP00000410681   ENSP00000418978   ENSP00000405343   ENSP00000418301  
     ENSP00000400817   ENSP00000417653   ENSP00000415395   ENSP00000419992   ENSP00000390397  
     ENSP00000398931   ENSP00000397855   ENSP00000417749  
    Reactome Protein details: Q9UJU6
    Human Recombinant Protein Products: 
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    Novus Biologicals DBNL Proteins
    Novus Biologicals DBNL Lysates
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    Uscn Proteins for DBNL

    Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001726ruffle IEA--
    GO:0005622intracellular ----
    GO:0005737cytoplasm ISS--
    GO:0005829cytosol TAS--
    GO:0005856cytoskeleton ----


    DBNL for ontologies           About GeneDecksing



    DBNL Antibody Products: 
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    ThermoFisher Antibodies for DBNL

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    Uscn ELISAs and CLIAs for DBNL


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DBNL for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR002108 Actin-bd_cofilin/tropomyosin
     IPR001452 SH3_domain

    Graphical View of Domain Structure for InterPro Entry Q9UJU6

    ProtoNet protein and cluster: Q9UJU6

    2 Blocks protein families:
    IPB001452 SH3 domain signature
    IPB002108 Actin-binding


    UniProtKB/Swiss-Prot: DBNL_HUMAN, Q9UJU6
    Domain: The SH3 domain mediates interaction with SHANK2, SHANK3 and PRAM1
    Similarity: Belongs to the ABP1 family
    Similarity: Contains 1 ADF-H domain
    Similarity: Contains 1 SH3 domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DBNL_HUMAN, Q9UJU6
    Function: Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in
    leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic
    function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and
    the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin
    polymerization, capping or bundling. Does not bind G-actin

         Genatlas biochemistry entry for DBNL:
    drebrin (actin-binding protein)-like

    miRNA
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    hsa-miR-345 hsa-miR-9 hsa-miR-133a hsa-miR-1208 hsa-miR-133b hsa-miR-24
    SwitchGear 3'UTR luciferase reporter plasmidDBNL 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding ISS--
    GO:0005515protein binding IPI19060904
    GO:0008022protein C-terminus binding IEA--
    GO:0008047enzyme activator activity TAS10567356
    GO:0019904protein domain specific binding IEA--


    DBNL for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Dbnltm1Jwnd for DBNL
         12 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Dbnl):
     behavior/neurological  cardiovascular system  cellular  growth/size  hematopoietic system 
     homeostasis/metabolism  immune system  integument  mortality/aging  nervous system 
     reproductive system  respiratory system 

    DBNL for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Apoptotic cleavage of cellular proteins
    Apoptotic cleavage of cellular proteins1.00
    Caspase-mediated cleavage of cytoskeletal proteins0.32
    Apoptotic execution phase0.73
    2TCR signaling in naive CD4+ T cells
    TCR signaling in naive CD4+ T cells1.00
    3JNK signaling in the CD4+ TCR pathway
    JNK signaling in the CD4+ TCR pathway1.00
    4Ubiquitinated Orc1 is degraded by the proteasome
    Apoptosis0.31
    5B cell receptor signaling pathway
    TCR Signaling Pathway0.19

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3 BioSystems Pathways for DBNL 
        TCR Signaling Pathway
    TCR signaling in naive CD4+ T cells
    JNK signaling in the CD4+ TCR pathway

    4        Reactome Pathways for DBNL
        Apoptotic execution phase
    Apoptotic cleavage of cellular proteins
    Caspase-mediated cleavage of cytoskeletal proteins
    Apoptosis



    DBNL for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DBNL

    5/113 Interacting proteins for DBNL (Q9UJU61, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 113)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006897endocytosis IEA--
    GO:0006915apoptotic process TAS--
    GO:0006921cellular component disassembly involved in execution phase of apoptosis TAS--
    GO:0007257activation of JUN kinase activity TAS10567356
    GO:0016601Rac protein signal transduction ISS--


    DBNL for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DBNL
    Search CenterWatch for drugs/clinical trials and news about DBNL 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DBNL gene (3 alternative transcripts): 
    NM_001014436.2  NM_001122956.1  NM_014063.6  

    Unigene Cluster for DBNL:

    Drebrin-like
    Hs.436500  [show with all ESTs]
    Unigene Representative Sequence: NM_001122956
    18/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22):
    ENST00000441840 ENST00000448521 ENST00000456905 ENST00000458579 ENST00000439983
    ENST00000440166 ENST00000464762 ENST00000439815 ENST00000498733 ENST00000452943
    ENST00000485932 ENST00000429716 ENST00000468694 ENST00000441904 ENST00000494774(uc003tjo.4 uc003tjq.4 uc003tjp.4 uc011kbm.2 uc011kbo.2 uc011kbp.2 uc011kbq.2 uc011kbn.2 uc011kbr.2 uc011kbs.2)
    ENST00000411855 ENST00000423561 ENST00000497184

    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate DBNL:
    hsa-miR-345 hsa-miR-9 hsa-miR-133a hsa-miR-1208 hsa-miR-133b hsa-miR-24
    SwitchGear 3'UTR luciferase reporter plasmidDBNL 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DBNL

    Additional cDNA sequence: 

    AF077353.1 AF151364.1 AF197060.1 AF218020.3 AF250287.1 AK027367.1 AK293151.1 AK293279.1 
    AK293340.1 AK293698.1 AK296778.1 AK298102.1 AK300630.1 AK302037.1 BC011677.2 BC031687.1 
    CR457167.1 

    24/30 DOTS entries (see all 30):

    DT.100753359  DT.100766319  DT.100828795  DT.216295  DT.410016  DT.121041177  DT.100828797  DT.121040879 
    DT.100828798  DT.100828803  DT.101984853  DT.121041104  DT.100828799  DT.92451241  DT.101984852  DT.100031036 
    DT.100828804  DT.100828808  DT.121040919  DT.121041013  DT.121041081  DT.121041117  DT.91912582  DT.100828806 

    24/527 AceView cDNA sequences (see all 527):

    BQ881240 BG740854 CR615718 BU147065 BG177219 AF077353 CR597853 AW571830 
    CR606615 AA349275 AL138082 BM914442 BM751546 BP373638 BQ425381 CB153716 
    BQ674152 BM810725 BQ059925 BQ670258 BC023589 BQ690891 BM810093 BQ671022 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for DBNL (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12 ^ 13a · 13b ·
    SP1:                          -     -           -                 -                       -     -                 -                                             
    SP2:                          -     -           -                 -                       -     -                                                               
    SP3:                          -     -           -                 -                       -     -                 -                                             
    SP4:                                                              -                                               -                                             
    SP5:                                -           -                 -                       -     -                                                               

    ExUns: 13c · 13d · 13e
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for DBNL

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DBNL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTCCTCCACG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See DBNL Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DBNL

    SOURCE GeneReport for Unigene cluster: Hs.436500
        SABiosciences Custom PCR Arrays for DBNL
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DBNL

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for DBNL gene from 7/26 species (see all 26)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves DBNL1 drebrin-like 71.85(n)
    68.17(a)
      425994  XM_423673.3  XP_423673.3 
    lizard
    (Anolis carolinensis)
    Reptilia DBNL6
    --
    68(a)
    1 ↔ 1
    GL343238.1(166405-183901)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC044296.12   -- 78(n)    BC044296.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb34f022 Transcribed sequence with weak similarity to protein more 76.99(n)    57040107 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG100831 CG10083 51.05(n)
    37.94(a)
      39520  NM_140400.1  NP_648657.1 
    worm
    (Caenorhabditis elegans)
    Secernentea K08E3.41 Protein K08E3.4 44.27(n)
    32.43(a)
      176813  NM_067439.3  NP_499840.1 
    A. gossypii yeast
    (Ashbya gossypii)
    Saccharomycetes AGOS_AGL237C1 AGL237Cp 39.33(n)
    28.05(a)
      4622723  NM_211492.1  NP_986430.1 


    ENSEMBL Gene Tree for DBNL (if available)
    TreeFam Gene Tree for DBNL (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DBNL gene
    DBN12  CTTN2  HCLS12  
    6 SIMAP similar genes for DBNL using alignment to 15 protein entries:     DBNL_HUMAN (see all proteins):
    DBN1    SH3GL1    SH3GL2    ARHGEF7    HCLS1    CTTN

    DBNL for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/368 NCBI SNPs in DBNL are shown (see all 368    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs102288231,2
    C,F,H,--44082242(+) CCTTAA/CGATTT 6 -- us2k1 int1 tfbs318Minor allele frequency- C:0.25NS EA NA CSA WA 2340
    rs1907494831,2
    --44082297(+) GATATG/TTAGAG 6 -- int1 us2k10--------
    rs1388389491,2
    --44082305(+) GAGTCA/GTCTTA 6 -- int1 us2k10--------
    rs720828271,2
    C,--44082316(+) TATTC-/CACTTAGCTGATT
    ATTCACACATATCACA
    CACTT
    6 -- int1 us2k10--------
    rs2003848091,2
    C--44082347(-) GCTAAG/TTGTGT 6 -- int1 us2k10--------
    rs1808053171,2
    --44082530(+) TACTAC/TATGTA 6 -- int1 us2k10--------
    rs1489610681,2
    --44082535(+) TATGTA/GTATAT 6 -- int1 us2k10--------
    rs1852362391,2
    --44082640(+) TGCATA/GTATAT 5 -- us2k1 int10--------
    rs1472320581,2
    --44082666(+) CATATA/GCATAT 5 -- us2k1 int10--------
    rs2015631661,2
    --44082673(+) TATGC-/ATATATA 5 -- us2k1 int10--------

    HapMap Linkage Disequilibrium report for DBNL (44084232 - 44109055 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for DBNL
         2 CNVs: 4531 31342

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DBNL for disorders           About GeneDecksing

    OMIM gene information: 610106    OMIM disorders: --

    2 diseases for DBNL:    About MalaCards
    cervicitis    eclampsia


    Export disorders for DBNL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DBNL gene, integrated from 9 sources (see all 45):
    (articles sorted by number of sources associating them with DBNL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Caspase-mediated cleavage of actin-binding and SH3-domain-containing proteins cortactin, HS1, and HIP-55 during apoptosis. (PubMed id 11689006)1, 2, 9 Chen Y.-R.... Tan T.-H. (2001)
    2. Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis. (PubMed id 14729663)1, 2, 9 Le Bras S....Deckert M. (2004)
    3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    6. PRAM-1 potentiates arsenic trioxide-induced JNK activation. (PubMed id 15637062)1, 2 Denis F.M.... Lutz P.G. (2005)
    7. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
    8. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 28988 HGNC: 2696 AceView: DBNL Ensembl:ENSG00000136279 euGenes: HUgn28988
    ECgene: DBNL H-InvDB: DBNL

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DBNL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DBNL gene:
    Search GeneIP for patents involving DBNL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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