V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

DBNL Gene

protein-coding GIFtS: 56

GC07P044050

drebrin-like
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ABP1 ^²
CMAP ^³
Drebrin-F ^³
HIP-55 ^¹, ², ³
SH3P7 ^¹, ², ³
drebrin-like ^²

Descriptions
Cervical SH3P7 ^³
Cervical mucin-associated protein ^³
HPK1-interacting protein of 55 kDa ^³
SH3 domain-containing protein 7 ^³
src homology 3 domain-containing protein HIP-55 ^²

External Ids
HGNC: 2696¹
Entrez Gene: 28988²
UniProtKB: Q9UJU6³
Ensembl: ENSG00000136279⁷

Search outside databases for aliases for DBNL gene

Previous GC identifers: GC07U990153 GC07P043857

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: DBNL_HUMAN, Q9UJU6

Function: Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling

pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin

cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that

regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and

endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or

bundling. Does not bind G-actin

Gene Wiki entry for DBNL (Drebrin-like)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DBNL gene

Entrez Gene cytogenetic band: 7p13 Ensembl cytogenetic band: 7p13 HGNC cytogenetic band: 7p13

DBNL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P044050: (about GC identifiers)

Start:	44,050,830 bp from pter
End:	44,067,840 bp from pter
Size:	17,011 bases
Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 44,123,799-44,140,805

RefSeq DNA sequence:

NC_000007.12 NT_007819.16 NT_079592.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: DBNL_HUMAN, Q9UJU6 (See protein sequence)

Recommended Name: Drebrin-like protein

Size: 430 amino acids; 48207 Da

Subunit: Interacts with SHANK2 and SHANK3 (By similarity). Interacts with FGD1, dynamin, MAP4K1 and

PRAM1

Subcellular location: Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note=Cortical

cytoskeleton. Associates with lamellipodial actin

Miscellaneous: Degraded by caspases during apoptosis

PDB structures from and Proteopedia :

1X67 (3D)

Secondary accessions: A4D2I9 P84070 Q6IAI8 Q96F30 Q96K74 Q9HBN8 Q9NR72

Alternative splicing: 3 isoforms: Q9UJU6-1 Q9UJU6-2 Q9UJU6-3

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (3 alternative transcripts):

NP_001014436.1 NP_001116428.1 NP_054782.2

ENSEMBL proteins:

ENSP00000258780 ENSP00000374020

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (HIP55)
	Human Recombinant Proteins from Abnova (DBNL)

OriGene Purified Recombinant Human Protein: DBNL

5/6 Gene Ontology (GO) cellular component terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001726	ruffle	IEA	--
GO:0005622	intracellular	IEA	--
GO:0005737	cytoplasm	ISS	--
GO:0005856	cytoskeleton	IEA	--
GO:0005938	cell cortex	ISS	--

About this table

Antibodies for DBNL:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for DBNL
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (HIP55), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (DBNL)
	Novus Biologicals Antibody for DBNL

Assays for DBNL:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9UJU6

ProtoNet protein and cluster: Q9UJU6

2 Blocks protein families:

IPB001452 SH3 domain signature

IPB002108 Actin-binding

UniProtKB/Swiss-Prot: DBNL_HUMAN, Q9UJU6

Domain: The SH3 domain mediates interaction with SHANK2, SHANK3 and PRAM1

Similarity: Belongs to the ABP1 family

Similarity: Contains 1 ADF-H domain

Similarity: Contains 1 SH3 domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DBNL)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001122956

Applied Biosystems Silencer® siRNAs for DBNL

Sigma-Aldrich siRNA for DBNL

Sigma-Aldrich shRNA Panels and shRNA for DBNL

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for DBNL
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001014436
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001014436
untagged cDNA clones in CMV expression vector (see all 3): NM_001014436

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001122956

UniProtKB/Swiss-Prot: DBNL_HUMAN, Q9UJU6

Function: Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling

pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin

cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that

regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and

endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or

bundling. Does not bind G-actin

Genatlas biochemistry entry for DBNL:

drebrin (actin-binding protein)-like

11 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Dbnl):

	behavior/neurological	growth/size	hematopoietic system	homeostasis/metabolism
immune system	lethality-prenatal/perinatal	nervous system	reproductive system	respiratory system
skin/coat/nails

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008047	enzyme activator activity	TAS	10567356
GO:0042802	identical protein binding	IPI	17353931
GO:0051015	actin filament binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for DBNL

5/32 Interacting proteins for DBNL (ENSP00000258780³ Q9UJU6^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 32 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SH3BP2	P78314²	STRING (score=.969) MINT-4563296 MINT-4563345 MINT-4563411 MINT-4549882 MINT-4563261 MINT-4563277 MINT-4563396
DBNL	Q9UJU6¹^,²	EBI-751783, EBI-751783 MINT-4563411 EBI-751783, EBI-751783 MINT-4563411
CDK4	P11802¹	EBI-751783, EBI-295644
CYP4F8	P98187¹	EBI-751783, EBI-1049983
DNPEP	Q9ULA0¹	EBI-751783, EBI-748356

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006897	endocytosis	IEA	--
GO:0006955	immune response	IEA	--
GO:0007257	activation of JUN kinase activity	TAS	10567356
GO:0016601	Rac protein signal transduction	ISS	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for DBNL

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DBNL)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001122956

Sigma-Aldrich siRNA for DBNL

Sigma-Aldrich shRNA Panels and shRNA for DBNL

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001014436 NM_001122956 NM_014063

REFSEQ mRNAs for DBNL gene (3 alternative transcripts):

NM_001014436.2 NM_001122956.1 NM_014063.6

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001014436 NM_001122956 NM_014063

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001014436
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001014436
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001014436

Additional cDNA sequence:

AF077353.1 AF151364.1 AF197060.1 AF218020.3 AF250287.1 AK027367.1 AK293151.1 AK293279.1

AK293340.1 AK293698.1 AK296778.1 AK298102.1 AK300630.1 AK302037.1 BC011677.2 BC031687.1

CR457167.1 CR593669.1 CR597853.1 CR599020.1 CR606615.1 CR614209.1 CR615718.1 CR626558.1

24/30 DOTS entries (see all 30 ):

DT.100753359 DT.100766319 DT.100828795 DT.216295 DT.410016 DT.100828797 DT.121041177 DT.121040879

DT.100828798 DT.100828803 DT.121041104 DT.101984853 DT.100828799 DT.92451241 DT.101984852 DT.100031036

DT.100828804 DT.121040919 DT.121041081 DT.100828808 DT.121041117 DT.91912582 DT.95098194 DT.100828806

24/527 AceView cDNA sequences (see all 527 ):

CD370570 BM759843 AA587756 NM_014063 BU540876 BU168183 CR614209 CB161625

BX114492 BQ423350 BQ300275 BM808785 BQ049324 BQ690891 BQ420321 BG676427

BQ671022 BG180312 BE907437 BM810725 BQ671329 BU147065 BM914861 BP347163

highest scoring ESTs for DBNL:

AA057835 AA149920 AA193529 AA335528 AA335848 AA349275 AA352416 AA548317 AA587756 AA632166

Unigene Cluster for DBNL:

Drebrin-like

Hs.436500 [show with all ESTs]

Unigene Representative Sequence: NM_001122956

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for DBNL (see all 11 )

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	^	2a	·	2b	·	2c	^	3	^	4	^	5a	·	5b	·	5c	^	6a	·	6b	·	6c	^	7	^	8	^	9a	·	9b	·	9c	^	10	^	11	^	12	^	13a	·	13b	·
SP1:									-		-				-						-								-		-						-
SP2:									-		-				-						-								-		-
SP3:									-		-				-						-								-		-						-
SP4:																					-																-
SP5:											-				-						-								-		-

ExUns:	13c	·	13d	·	13e
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for DBNL

2 Ensembl transcripts including schematic representations:

ENST00000258780 ENST00000389369

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

DBNL expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DBNL

¹ / ² / ³

5 probe-sets matching DBNL gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
67173_at²^{, 3}	U95-E	1	1.00	1.00	0.29	1.09	H20808	0.20	1.00	0.72	1
48577_at²^{, 3}	U95-B	1	1.00	1.00	0.66	1.34	AW005562	0.80	1.00	0.91	1
88842_r_at²^{, 3}	U95-E	1	1.00	1.00	0.93	0.59	AA845683	0.40	1.00	0.76	1
222429_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AF077353	0.80	1.00	0.91	1
222429_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks DBNL for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TTCCTCCACG

SOURCE GeneReport for Unigene cluster: Hs.436500

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DBNL gene from 5/13 species (see all 13 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DBNL¹	--	drebrin-like	86.12(n) 87.76(a)	607412 XM_851158.1 XP_856251.1
chimpanzee (Pan troglodytes)	DBNL¹	--	drebrin-like	99.38(n) 99.54(a)	463925 XM_001141747.1 XP_001141747.1
cow (Bos taurus)	DBNL¹	--	drebrin-like	88.16(n) 87.76(a)	514706 XM_592601.3 XP_592601.2
rat (Rattus norvegicus)	Dbnl¹	--	drebrin-like	85.31(n) 86.25(a)	83527 NM_031352.1 NP_112642.1
mouse (Mus musculus)	Dbnl^{1, 5}	11 (1.00 cM)⁵	drebrin-like^{1, 5}	84.54(n)¹ 86.95(a)¹	13169¹ NM_013810.2¹ NP_038838.1¹ AA000682⁵ AA017916⁵ (see all 43)

About this table Species with no ortholog for DBNL

ENSEMBL Gene Tree for DBNL

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for DBNL gene

DBN1² HCLS1² CTTN²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/89 NCBI SNPs in DBNL are shown (see all 89 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 41)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs4430012^1,2	A,F	44050817(+)	`CGGCCG/CGGCCC`	3	--	ut5¹ tfbs³		2		MN EA	356
	rs17553434^1,2	F	44050735(+)	`CCCCTA/GCCATT`	2	--	ng5¹		2		MN EA	356
	rs17553427^1,2	F	44050642(+)	`CCTCCC/GTTCTC`	2	--	ng5¹ trp³		2		MN EA	356
--	rs4724275^1,2	C	44049289(+)	`tatacA/Ctatgc`	2	--	ng5¹		0	--	--	--	--
	rs17551738^1,2	F	44050299(+)	`TCAGTT/CAGGTT`	2	--	ng5¹		2		MN EA	356
	rs17551744^1,2	F	44050536(+)	`GTCCCT/CGCGGC`	2	--	ng5¹		2		MN EA	356
	rs11552797^1,2	C,F,H	44066189(+)	`GGTGCC/TGGCTC`	3	A/A	syn¹		6		MN NA EU EA WA	678
	rs4724277^1,2	A,C,F,H	44063335(+)	`ACTGGA/CACATC`	2	--	int¹		12		EA NA EU WA	1038
	rs10951755^1,2	A,C,F,H	44059248(+)	`TGCATG/TGGAGG`	2	--	int¹		4		EU EA WA	418
	rs10951756^1,2	A,C,F,H	44066598(+)	`CAGGCG/TTCCCT`	2	--	int¹		4		EU EA WA	412

About this table

HapMap Linkage Disequilibrium images for DBNL (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 610106

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/32 PubMed articles for DBNL gene (see all 32 ):

Caspase-mediated cleavage of actin-binding and SH3-domain-containing proteins cortactin, HS1, and HIP-55 during apoptosis. (PubMed id 11689006)^{1, 3, 4} Chen Y.-R.... Tan T.-H. (2001)
Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis. (PubMed id 14729663)^{1, 3, 4} Le Bras S....Deckert M. (2004)
A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)^{3, 4} Beausoleil S.A.... Gygi S.P. (2006)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
PRAM-1 potentiates arsenic trioxide-induced JNK activation. (PubMed id 15637062)^{3, 4} Denis F.M.... Lutz P.G. (2005)
Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. (PubMed id 16094384)^{3, 4} Tao W.A.... Aebersold R. (2005)
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)^{3, 4} Rush J.... Comb M.J. (2005)
Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)^{3, 4} Wan D....Gu J. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 28988	HGNC: 2696	AceView: DBNL	Ensembl:ENSG00000136279	euGenes: HUgn28988
ECgene: DBNL	H-InvDB: DBNL

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for DBNL
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for DBNL:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DBNL-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DBNL		Antibodies for DBNL
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DBNL		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (DBNL)
	Antibodies (DBNL)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (HIP55)
	Antibodies (HIP55)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for DBNL

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for DBNL

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
DBNL Gene at Home site.
Version 2.41.1
server4.xennexinc.com

DBNL Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for DBNL

Summaries
for DBNL

Genomic Location
for DBNL

Proteins
for DBNL

Protein Domains/
Families
for DBNL

Gene Function
for DBNL

Pathways & Interactions
for DBNL

Drugs & Compounds
for DBNL

Transcripts
for DBNL

Expression
for DBNL

Orthologs
for DBNL

Paralogs
for DBNL

SNPs/Variants
for DBNL

Disorders & Mutations
for DBNL

Medical News
for DBNL

Publications
for DBNL

Search for DBNL

Genome Databases showing DBNL

Other Databases showing DBNL

Specialized Databases showing DBNL

Licensable Technologies
for DBNL

Services
for DBNL

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DBNL Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor DBNL

Summariesfor DBNL

Genomic Locationfor DBNL

Proteinsfor DBNL

Protein Domains/Familiesfor DBNL

Gene Functionfor DBNL

Pathways & Interactionsfor DBNL

Drugs & Compoundsfor DBNL

Transcriptsfor DBNL

Expression for DBNL

Orthologsfor DBNL

Paralogsfor DBNL

SNPs/Variantsfor DBNL

Disorders & Mutationsfor DBNL

Medical Newsfor DBNL

Publicationsfor DBNL

Search for DBNL

Genome Databases showing DBNL

Other Databases showing DBNL

Specialized Databases showing DBNL

Licensable Technologiesfor DBNL

Servicesfor DBNL

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DBNL

Summaries
for DBNL

Genomic Location
for DBNL

Proteins
for DBNL

Protein Domains/
Families
for DBNL

Gene Function
for DBNL

Pathways & Interactions
for DBNL

Drugs & Compounds
for DBNL

Transcripts
for DBNL

Expression
for DBNL

Orthologs
for DBNL

Paralogs
for DBNL

SNPs/Variants
for DBNL

Disorders & Mutations
for DBNL

Medical News
for DBNL

Publications
for DBNL

Licensable Technologies
for DBNL

Services
for DBNL