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DBNDD2 Gene

protein-coding   GIFtS: 42
GCID: GC20P044034

Dysbindin (Dystrobrevin Binding Protein 1) Domain Containing...

(Previous name: chromosome 20 open reading frame 35)
(Previous symbol: C20orf35)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Dysbindin (Dystrobrevin Binding Protein 1) Domain Containing 21 2     CK1BP2 3
C20orf351 2 3     Chromosome 20 Open Reading Frame 351
HSMNP12 3 5     Dysbindin Domain-Containing Protein 22
Casein Kinase-1 Binding Protein2 3     SCF Apoptosis Response Protein 12

External Ids:    HGNC: 158811   Entrez Gene: 558612   Ensembl: ENSG000002442747   OMIM: 6114535   UniProtKB: Q9BQY93   

Export aliases for DBNDD2 gene to outside databases

Previous GC identifers: GC20P043426 GC20P043468 GC20P040776


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for DBNDD2 Gene:
DBNDD2 (dysbindin (dystrobrevin binding protein 1) domain containing 2) is a protein-coding gene. Diseases associated with DBNDD2 include intrahepatic cholangiocarcinoma, and cholangiocarcinoma. An important paralog of this gene is DTNBP1.

UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9
Function: May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro)

Gene Wiki entry for DBNDD2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the DBNDD2 gene promoter:
         CRE-BP1   ATF-2   Lmo2   Nkx2-5   STAT5A   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for DBNDD2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DBNDD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.12   Ensembl cytogenetic band:  20q13.12   HGNC cytogenetic band: 20q13.12

DBNDD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DBNDD2 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P044034:  view genomic region     (about GC identifiers)

Start:
44,034,633 bp from pter      End:
44,039,250 bp from pter
Size:
4,618 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9 (See protein sequence)
Recommended Name: Dysbindin domain-containing protein 2  
Size: 259 amino acids; 27671 Da
Subunit: Monomer. Interacts with CSNK1D and CSNK1E
Secondary accessions: Q331S6 Q5QPV4 Q5QPV6 Q9BQZ0 Q9BVL1 Q9H1F6 Q9NWZ0 Q9NY07 Q9NZ31
Alternative splicing: 4 isoforms:  Q9BQY9-1   Q9BQY9-2   Q9BQY9-3   Q9BQY9-4   

Explore the universe of human proteins at neXtProt for DBNDD2: NX_Q9BQY9

Explore proteomics data for DBNDD2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See DBNDD2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (9 alternative transcripts): 
    NP_001041686.1  NP_001041687.1  NP_001041688.1  NP_001041689.1  NP_001041690.2  NP_001041691.2  NP_001184068.1  NP_001184069.1  
    NP_060948.3  

    ENSEMBL proteins: 
     ENSP00000361808   ENSP00000361807   ENSP00000349822   ENSP00000361805   ENSP00000361802  
     ENSP00000354250   ENSP00000361797   ENSP00000361795   ENSP00000414161  

    DBNDD2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for DBNDD2
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    Novus Biologicals DBNDD2 Proteins
    Novus Biologicals DBNDD2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for DBNDD2
    Cloud-Clone Corp. Proteins for DBNDD2

    DBNDD2 Antibody Products:

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    Abcam antibodies for DBNDD2
    Cloud-Clone Corp. Antibodies for DBNDD2
    ThermoFisher Antibodies for DBNDD2
    Search LSBio for Antibodies for DBNDD2

    DBNDD2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for DBNDD2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for DBNDD2
    Cloud-Clone Corp. CLIAs for DBNDD2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007531 Dysbindin

    Graphical View of Domain Structure for InterPro Entry Q9BQY9

    ProtoNet protein and cluster: Q9BQY9

    UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9
    Similarity: Belongs to the dysbindin family


    DBNDD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DBND2_HUMAN, Q9BQY9
    Function: May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16618118
         
    DBNDD2 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Dbndd2 (no phenotypes)

    DBNDD2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DBNDD2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for DBNDD2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DBNDD2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for DBNDD2

    miRNA
    Products:
        
    miRTarBase miRNAs that target DBNDD2:
    hsa-let-7b-5p (MIRT052207)

    Block miRNA regulation of human, mouse, rat DBNDD2 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate DBNDD2:
    hsa-miR-24-2* hsa-miR-374b* hsa-miR-214 hsa-miR-24-1* hsa-miR-2276 hsa-miR-622 hsa-miR-761
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat DBNDD2

    Gene Editing
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    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 9): DBNDD2 (NM_001197139)
    Sino Biological Human cDNA Clone for DBNDD2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DBNDD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DBNDD2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for DBNDD2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DBNDD2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    extracellular1
    lysosome1
    vacuole1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    DBNDD2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for DBNDD2
    Interactions:

        Search GeneGlobe Interaction Network for DBNDD2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for DBNDD2 (Q9BQY92, 3 ENSP000003498224) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALCOCO2Q131372, 3, ENSP000002589474MINT-67062 I2D: score=3 STRING: ENSP00000258947
    PLEKHA5Q9HAU03I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006469negative regulation of protein kinase activity IDA16618118

    DBNDD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for DBNDD2 (DBND2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for DBNDD2 gene (9 alternative transcripts): 
    NM_001048221.2  NM_001048222.2  NM_001048223.2  NM_001048224.2  NM_001048225.2  NM_001048226.2  NM_001197139.1  NM_001197140.1  
    NM_018478.3  

    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372723(uc002xnz.3) ENST00000372722(uc002xoa.3) ENST00000357275(uc021wei.1 uc021wej.1)
    ENST00000372720(uc002xob.3) ENST00000372717(uc002xoc.3 uc002xod.3)
    ENST00000360981 ENST00000372712 ENST00000372710(uc002xog.3 uc002xof.3)
    ENST00000443296

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat DBNDD2 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate DBNDD2:
    hsa-miR-24-2* hsa-miR-374b* hsa-miR-214 hsa-miR-24-1* hsa-miR-2276 hsa-miR-622 hsa-miR-761
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for DBNDD2
    Predesigned siRNA for gene silencing in human, mouse, rat DBNDD2
    Clone
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    OriGene clones in human, mouse for DBNDD2 (see all 38)
    OriGene ORF clones in mouse, rat for DBNDD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 9): DBNDD2 (NM_001197139)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DBNDD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DBNDD2
    Primer
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    OriGene qPCR primer pairs and template standards for DBNDD2
    OriGene qSTAR qPCR primer pairs in human, mouse for DBNDD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat DBNDD2
      QuantiTect SYBR Green Assays in human, mouse, rat DBNDD2
      QuantiFast Probe-based Assays in human, mouse, rat DBNDD2

    Selected AceView cDNA sequences (see all 656):

    CA503318 AI149677 CR605916 BM763158 CR618346 BQ073014 CR604473 BI518572 
    H61766 AI540683 AA987265 AL591565 AI878979 AA766838 AA994128 AL532475 
    BF432406 AI743004 BU849696 CR622797 AW341688 AI243428 BF928817 CA430828 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    DBNDD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGCCTCCTT
    DBNDD2 Expression
    About this image


    DBNDD2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             Thalamus
             Caudate nucleus   
     
     Heart (Cardiovascular System)
     
     Spinal Cord (Nervous System)
    DBNDD2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    DBNDD2 Protein Expression

    UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9
    Tissue specificity: Detected in brain

        Custom PCR Arrays for DBNDD2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DBNDD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DBNDD2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dbndd21 , 5 dysbindin (dystrobrevin binding protein 1) domain containing more1, 5 80.8(n)1
    79.11(a)1
      2 (85.17 cM)5
    528401  NM_026797.21  NP_081073.11 
     1644861065 
    chicken
    (Gallus gallus)
    Aves DBNDD21 dysbindin (dystrobrevin binding protein 1) domain containing more 60.75(n)
    52.63(a)
      419180  XM_417359.4  XP_417359.2 
    lizard
    (Anolis carolinensis)
    Reptilia DBNDD26
    dysbindin (dystrobrevin binding protein 1) domain ...
    42(a)
    1 ↔ 1
    GL343291.1(1604228-1615168)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC536352 similar to chromosome 20 open reading frame 169 73.25(n)    BC041757.1 
    zebrafish
    (Danio rerio)
    Actinopterygii DBNDD26
    dysbindin (dystrobrevin binding protein 1) domain ...
    30(a)
    1 ↔ 1
    11(7127817-7165162) ENSDARG00000074904
    corn
    (Zea mays)
    Liliopsida Zm.175242 Zea mays transcribed sequence with weak similarity more 74.94(n)    CD448014.1 


    ENSEMBL Gene Tree for DBNDD2 (if available)
    TreeFam Gene Tree for DBNDD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for DBNDD2 gene
    DTNBP12  
    1 SIMAP similar gene for DBNDD2 using alignment to 2 protein entries:     DBND2_HUMAN (see all proteins):
    DTNBP1

    DBNDD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing DBNDD2
    DNA2.0 Custom Variant and Variant Library Synthesis for DBNDD2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611453    OMIM disorders: --

    3 diseases for DBNDD2:    
    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    parkinson's disease


    DBNDD2 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for DBNDD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for DBNDD2 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with DBNDD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1. (PubMed id 16618118)1, 2 Yin H.... Kuret J. (Biochemistry 2006)
    2. The human orthologue of a novel apoptosis response gene induced during rat myelomonocytic stem cell apoptosis maps to 20q13.12. (PubMed id 16305340)1, 2 Lucas T.... Jansen B. (Stem Cells Dev. 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    6. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    7. Identification of genes related to Parkinson's disease using expressed sequence tags. (PubMed id 17213182)1 Kim J.M.... Kim N.S. (DNA Res. 2006)
    8. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (Biochem. Biophys. Res. Commun. 2006)
    9. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55861 HGNC: 15881 AceView: C20orf35 Ensembl:ENSG00000244274 euGenes: HUgn55861
    ECgene: DBNDD2 H-InvDB: DBNDD2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for DBNDD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for DBNDD2 gene:
    Search GeneIP for patents involving DBNDD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for DBNDD2  
     OriGene qPCR primer pairs and template standards for DBNDD2   OriGene Protein Over-expression Lysate for DBNDD2  
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     Block miRNA regulation of human, mouse, rat DBNDD2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing DBNDD2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat DBNDD2 Predesigned siRNA for gene silencing in human, mouse, rat DBNDD2
     QuantiFast Probe-based Assays in human, mouse, rat DBNDD2 QuantiTect SYBR Green Assays in human, mouse, rat DBNDD2
     Custom PCR Arrays for DBNDD2 Search Chromatin IP Primers for DBNDD2
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     Search Tocris compounds for DBNDD2 (DBND2)
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
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     Browse ESI BIO Cell Lines and PureStem Progenitors for DBNDD2
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     ThermoFisher Antibodies for DBNDD2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DBNDD2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for DBNDD2
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     Search LSBio for Antibodies for DBNDD2
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