Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DBNDD2 Gene

protein-coding   GIFtS: 46
GCID: GC20P044034

dysbindin (dystrobrevin binding protein 1) domain containing...

(Previous name: chromosome 20 open reading frame 35 )
(Previous symbol: C20orf35)
 Explore 3 diseases affiliated with
DBNDD2 via our new
 Human Malady Compendium 
Biological research products
for DBNDD2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Dysbindin (Dystrobrevin Binding Protein 1) Domain Containing 21 2     CK1BP2 3
HSMNP11 2 3 5     Chromosome 20 Open Reading Frame 351
C20orf351 2 3     Dysbindin Domain-Containing Protein 22
Casein Kinase-1 Binding Protein2 3     SCF Apoptosis Response Protein 12

External Ids:    HGNC: 158811   Entrez Gene: 558612   Ensembl: ENSG000002442747   OMIM: 6114535   UniProtKB: Q9BQY93   

Export aliases for DBNDD2 gene to outside databases

Previous GC identifers: GC20P043426 GC20P043468 GC20P040776


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9
Function: May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro)

Gene Wiki entry for DBNDD2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011362.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DBNDD2 gene promoter:
         CRE-BP1   ATF-2   Lmo2   Nkx2-5   STAT5A   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for DBNDD2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DBNDD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.12   Ensembl cytogenetic band:  20q13.12   HGNC cytogenetic band: 20q13.12

DBNDD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DBNDD2 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P044034:  view genomic region     (about GC identifiers)

Start:
44,034,671 bp from pter      End:
44,039,250 bp from pter
Size:
4,580 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9 (See protein sequence)
Recommended Name: Dysbindin domain-containing protein 2  
Size: 259 amino acids; 27671 Da
Subunit: Monomer. Interacts with CSNK1D and CSNK1E
Secondary accessions: Q5QPV4 Q9BQZ0 Q9BVL1 Q9H1F6 Q9NWZ0 Q9NY07 Q9NZ31
Alternative splicing: 3 isoforms:  Q9BQY9-1   Q9BQY9-2   Q9BQY9-3   

Explore the universe of human proteins at neXtProt for DBNDD2: NX_Q9BQY9

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BQY9

  • DBNDD2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (9 alternative transcripts): 
    NP_001041686.1  NP_001041687.1  NP_001041688.1  NP_001041689.1  NP_001041690.2  NP_001041691.2  NP_001184068.1  NP_001184069.1  
    NP_060948.3  

    ENSEMBL proteins: 
     ENSP00000361808   ENSP00000361807   ENSP00000349822   ENSP00000361805   ENSP00000361802  
     ENSP00000354250   ENSP00000361797   ENSP00000361795   ENSP00000414161  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: DBNDD2
    OriGene Protein Over-expression Lysate (see all 5): DBNDD2
    OriGene Custom Protein Services for DBNDD2 
    GenScript Custom Purified and Recombinant Proteins Services for DBNDD2
    Novus Biologicals DBNDD2 Proteins
    Novus Biologicals DBNDD2 Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for DBNDD2
    Uscn Proteins for DBNDD2

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--


    DBNDD2 for ontologies           About GeneDecksing



    DBNDD2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for DBNDD2 
    GenScript Custom Superior Antibodies Services for DBNDD2
    Novus Biologicals DBNDD2 Antibody
    Search for Antibodies for DBNDD2 at Abcam  
    Uscn Antibodies for DBNDD2
    ThermoFisher Antibody for DBNDD2

    Assay Products for DBNDD2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for DBNDD2
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for DBNDD2


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DBNDD2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007531 Dysbindin

    Graphical View of Domain Structure for InterPro Entry Q9BQY9

    ProtoNet protein and cluster: Q9BQY9

    UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9
    Similarity: Belongs to the dysbindin family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9
    Function: May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro)

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 6): DBNDD2
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DBNDD2
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate DBNDD2:
    hsa-miR-24-2* hsa-miR-374b* hsa-miR-214 hsa-miR-24-1* hsa-miR-2276 hsa-miR-622 hsa-miR-761
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DBNDD2 (see all 7)
    OriGene shRNA RFP: DBNDD2
    OriGene siRNA: DBNDD2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DBNDD2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for DBNDD2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD2 (see all 9)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD2 (see all 6)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 9): DBNDD2 (NM_001197139)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DBNDD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DBNDD2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for DBNDD2
    Search LifeMap BioReagents cell lines for DBNDD2

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DBNDD2

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16618118


    DBNDD2 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DBNDD2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for DBNDD2 (Q9BQY92, 3 ENSP000003498224) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALCOCO2Q131372, 3, ENSP000002589474MINT-67062 I2D: score=3 STRING: ENSP00000258947
    PLEKHA5Q9HAU03I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006469negative regulation of protein kinase activity IDA16618118


    DBNDD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DBNDD2
    Search CenterWatch for drugs/clinical trials and news about DBNDD2 / DBND2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DBNDD2 gene (9 alternative transcripts): 
    NM_001048221.2  NM_001048222.2  NM_001048223.2  NM_001048224.2  NM_001048225.2  NM_001048226.2  NM_001197139.1  NM_001197140.1  
    NM_018478.3  

    Unigene Cluster for DBNDD2:

    Dysbindin (dystrobrevin binding protein 1) domain containing 2
    Hs.730643  [show with all ESTs]
    Unigene Representative Sequence: AK098015
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372723(uc002xnz.3) ENST00000372722(uc002xoa.3) ENST00000357275(uc021wei.1 uc021wej.1)
    ENST00000372720(uc002xob.3) ENST00000372717(uc002xoc.3 uc002xod.3)
    ENST00000360981 ENST00000372712 ENST00000372710(uc002xog.3 uc002xof.3)
    ENST00000443296

    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 6): DBNDD2
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DBNDD2
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate DBNDD2:
    hsa-miR-24-2* hsa-miR-374b* hsa-miR-214 hsa-miR-24-1* hsa-miR-2276 hsa-miR-622 hsa-miR-761
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DBNDD2 (see all 7)
    OriGene shRNA RFP: DBNDD2
    OriGene siRNA: DBNDD2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DBNDD2
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD2 (see all 9)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD2 (see all 6)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 9): DBNDD2 (NM_001197139)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DBNDD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DBNDD2 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DBNDD2
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DBNDD2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DBNDD2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DBNDD2

    Additional cDNA sequence: 

    AF220191.1 AJ276469.1 AK000531.1 AK098015.1 AL591565.1 AY113697.1 BC001105.2 BC012818.2 
    NR_003189.2 

    18 DOTS entries:

    DT.100810477  DT.100697234  DT.444894  DT.95364384  DT.120830931  DT.100030231  DT.91756231  DT.100810474 
    DT.95364385  DT.91756220  DT.95316815  DT.97783053  DT.91756228  DT.95364387  DT.97855931  DT.101972588 
    DT.120830963  DT.86839111 

    24/656 AceView cDNA sequences (see all 656):

    CA503318 AI149677 BM763158 CR605916 CR618346 BQ073014 CR604473 BI518572 
    H61766 AI540683 AA987265 AI878979 AL591565 AA766838 AA994128 AL532475 
    BF432406 AI743004 CR622797 BU849696 AW341688 BF928817 AI243428 BM505581 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DBNDD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTGCCTCCTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    DBNDD2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See DBNDD2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DBNDD2

    SOURCE GeneReport for Unigene cluster: Hs.730643

    UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9
    Tissue specificity: Detected in brain

        SABiosciences Custom PCR Arrays for DBNDD2
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DBNDD2
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DBNDD2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DBNDD2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DBNDD2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DBNDD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DBNDD2 gene from 7/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dbndd21 , 5 dysbindin (dystrobrevin binding protein 1) domain containing more1, 5 84.39(n)1
    85.44(a)1
      2 (85.17 cM)5
    528401  NM_026797.21  NP_081073.11 
     1644861065 
    chicken
    (Gallus gallus)
    Aves DBNDD21 dysbindin (dystrobrevin binding protein 1) domain containing more 60.65(n)
    52.9(a)
      419180  XM_417359.3  XP_417359.2 
    lizard
    (Anolis carolinensis)
    Reptilia DBNDD26
    --
    46(a)
    1 ↔ 1
    GL343291.1(1604987-1615168)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC536352 similar to chromosome 20 open reading frame 169 73.25(n)    BC041757.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CR925817.26
    --
    32(a)
    1 ↔ 1
    11(7127817-7165162)
    fruit fly
    (Drosophila melanogaster)
    Insecta dysb6
    dysbindin
    11(a)
    1 → many
    3L(18860871-18862319)
    corn
    (Zea mays)
    Liliopsida Zm.175242 Zea mays transcribed sequence with weak similarity more 74.94(n)    CD448014.1 


    ENSEMBL Gene Tree for DBNDD2 (if available)
    TreeFam Gene Tree for DBNDD2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DBNDD2 gene
    DTNBP12  
    2 SIMAP similar genes for DBNDD2 using alignment to 3 protein entries:     DBND2_HUMAN (see all proteins):
    C20orf35    DTNBP1

    DBNDD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/134 NCBI SNPs in DBNDD2 are shown (see all 134    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1864189251,2
    --44032693(+) CCCTCA/TTTTTC 4 -- us2k1 int10--------
    rs1908679231,2
    --44032727(+) ATCTAC/TTCTAT 4 -- us2k1 int10--------
    rs124809121,2
    C,H,--44032870(+) gggctG/Taaatt 6 -- us2k1 int10--------
    rs27432481,2
    C,F,--44033090(+) GACAGC/TAGTTC 6 -- us2k1 int110Minor allele frequency- T:0.22NA WA CSA EA 508
    rs1164372561,2
    --44033495(+) TGAATG/ATGTCA 8 -- us2k1 int11Minor allele frequency- A:0.01WA 118
    rs1152520131,2
    --44033660(+) AGGGGG/AGCACA 8 -- us2k1 int11Minor allele frequency- A:0.01WA 118
    rs30916851,2
    C,F,A,H,--44033686(+) GAAATG/TACAGC 8 -- us2k1 int112Minor allele frequency- T:0.17NS EA NA WA 1092
    rs1860331321,2
    --44033715(+) ATGGAA/GTGTAG 8 -- us2k1 int10--------
    rs1912562221,2
    --44033802(+) AGGCCA/GAGGCG 8 -- us2k1 int10--------
    rs116994551,2
    C,H--44033895(+) ccgggC/Tgcggt 8 -- us2k1 int10--------

    HapMap Linkage Disequilibrium report for DBNDD2 (44034671 - 44039250 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DBNDD2: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DBNDD2
    DNA2.0 Custom Variant and Variant Library Synthesis for DBNDD2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DBNDD2 for disorders           About GeneDecksing

    OMIM gene information: 611453    OMIM disorders: --

    3 diseases for DBNDD2:    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    parkinson's disease


    Export disorders for DBNDD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DBNDD2 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with DBNDD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1. (PubMed id 16618118)1, 2 Yin H.... Kuret J. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    5. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
    6. Identification of genes related to Parkinson's disease using expressed sequence tags. (PubMed id 17213182)1 Kim J.M....Kim N.S. (2006)
    7. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (2006)
    8. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
    9. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    10. The human orthologue of a novel apoptosis response gene induced during rat myelomonocytic stem cell apoptosis maps to 20q13.12. (PubMed id 16305340)1 Lucas T.... Jansen B. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55861 HGNC: 15881 AceView: C20orf35 Ensembl:ENSG00000244274 euGenes: HUgn55861
    ECgene: DBNDD2 H-InvDB: DBNDD2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DBNDD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DBNDD2 gene:
    Search GeneIP for patents involving DBNDD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for DBNDD2  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DBNDD2   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DBNDD2  
     OriGene Protein Over-expression Lysate for DBNDD2   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for DBNDD2   OriGene 3'-UTR Clone for DBNDD2  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD2   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD2  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for DBNDD2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for DBNDD2   OriGene Custom Protein Services for DBNDD2  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DBNDD2
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DBNDD2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DBNDD2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DBNDD2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DBNDD2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DBNDD2
     GenScript Custom Purified and Recombinant Proteins Services for DBNDD2 GenScript cDNA clones with any tag delivered in your preferred vector for DBNDD2
     GenScript Custom Assay Services for DBNDD2 GenScript Custom Superior Antibodies Services for DBNDD2
     GenScript Custom overexpressing Cell Line Services for DBNDD2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in DBNDD2 promoter
     Search Chromatin IP Primers for DBNDD2
     RT2 qPCR Primer Assay in human, mouse, rat DBNDD2
     Search GNC Networks for DBNDD2
     SABiosciences Custom PCR Arrays for DBNDD2
     Search Tocris compounds for DBNDD2
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     DBNDD2 antibodies
     DBNDD2 proteins
     DBNDD2 lysates
     Search for Antibodies for DBNDD2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for DBNDD2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for DBNDD2




     DBNDD2 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for DBNDD2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DBNDD2
     Browse SwitchGear 3'UTR luciferase reporter plasmids for DBNDD2
     Browse SwitchGear Promoter luciferase reporter plasmids for DBNDD2
     ThermoFisher Antibody for DBNDD2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DBNDD2
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      DBNDD2 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4