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Aliases for DBNDD2 Gene

Aliases for DBNDD2 Gene

  • Dysbindin Domain Containing 2 2 3
  • Dysbindin (Dystrobrevin Binding Protein 1) Domain Containing 2 2 3 5
  • Casein Kinase-1 Binding Protein 3 4
  • C20orf35 3 4
  • HSMNP1 3 4
  • CK1BP 3 4
  • Chromosome 20 Open Reading Frame 35 2
  • SCF Apoptosis Response Protein 1 3

External Ids for DBNDD2 Gene

Previous HGNC Symbols for DBNDD2 Gene

  • C20orf35

Previous GeneCards Identifiers for DBNDD2 Gene

  • GC20P043426
  • GC20P043468
  • GC20P044034
  • GC20P040776

Summaries for DBNDD2 Gene

GeneCards Summary for DBNDD2 Gene

DBNDD2 (Dysbindin Domain Containing 2) is a Protein Coding gene. An important paralog of this gene is DTNBP1.

UniProtKB/Swiss-Prot for DBNDD2 Gene

  • May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro).

Gene Wiki entry for DBNDD2 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DBNDD2 Gene

Genomics for DBNDD2 Gene

Regulatory Elements for DBNDD2 Gene

Enhancers for DBNDD2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around DBNDD2 on UCSC Golden Path with GeneCards custom track

Promoters for DBNDD2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around DBNDD2 on UCSC Golden Path with GeneCards custom track

Genomic Location for DBNDD2 Gene

45,405,993 bp from pter
45,410,610 bp from pter
4,618 bases
Plus strand

Genomic View for DBNDD2 Gene

Genes around DBNDD2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DBNDD2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DBNDD2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DBNDD2 Gene

Proteins for DBNDD2 Gene

  • Protein details for DBNDD2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Dysbindin domain-containing protein 2
    Protein Accession:
    Secondary Accessions:
    • Q331S6
    • Q5QPV4
    • Q5QPV6
    • Q9BQZ0
    • Q9BVL1
    • Q9H1F6
    • Q9NWZ0
    • Q9NY07
    • Q9NZ31

    Protein attributes for DBNDD2 Gene

    259 amino acids
    Molecular mass:
    27671 Da
    Quaternary structure:
    • Monomer. Interacts with CSNK1D and CSNK1E.

    Alternative splice isoforms for DBNDD2 Gene


neXtProt entry for DBNDD2 Gene

Proteomics data for DBNDD2 Gene at MOPED

Post-translational modifications for DBNDD2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for DBNDD2 Gene

Domains & Families for DBNDD2 Gene

Protein Domains for DBNDD2 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the dysbindin family.
  • Belongs to the dysbindin family.
genes like me logo Genes that share domains with DBNDD2: view

No data available for Gene Families for DBNDD2 Gene

Function for DBNDD2 Gene

Molecular function for DBNDD2 Gene

UniProtKB/Swiss-Prot Function:
May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro).

Phenotypes for DBNDD2 Gene

MGI mutant phenotypes for DBNDD2:
inferred from 1 alleles
GenomeRNAi human phenotypes for DBNDD2:
genes like me logo Genes that share phenotypes with DBNDD2: view

Animal Models for DBNDD2 Gene

MGI Knock Outs for DBNDD2:

Animal Model Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DBNDD2 Gene

Localization for DBNDD2 Gene

Subcellular locations from

Jensen Localization Image for DBNDD2 Gene COMPARTMENTS Subcellular localization image for DBNDD2 gene
Compartment Confidence
cytosol 2
nucleus 2
lysosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for DBNDD2 Gene

Pathways & Interactions for DBNDD2 Gene

SuperPathways for DBNDD2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for DBNDD2 Gene


No data available for Pathways by source and SIGNOR curated interactions for DBNDD2 Gene

Drugs & Compounds for DBNDD2 Gene

No Compound Related Data Available

Transcripts for DBNDD2 Gene

Unigene Clusters for DBNDD2 Gene

Dysbindin (dystrobrevin binding protein 1) domain containing 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DBNDD2 Gene

No ASD Table

Relevant External Links for DBNDD2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for DBNDD2 Gene

mRNA expression in normal human tissues for DBNDD2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for DBNDD2 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x6.6) and Brain - Substantia nigra (x4.4).

SOURCE GeneReport for Unigene cluster for DBNDD2 Gene Hs.730643

mRNA Expression by UniProt/SwissProt for DBNDD2 Gene

Tissue specificity: Detected in brain.
genes like me logo Genes that share expression patterns with DBNDD2: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for DBNDD2 Gene

Orthologs for DBNDD2 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for DBNDD2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia DBNDD2 35
  • 85.42 (n)
  • 87.5 (a)
  • 69 (a)
(Canis familiaris)
Mammalia DBNDD2 35
  • 88.05 (n)
  • 88.05 (a)
  • 85 (a)
(Mus musculus)
Mammalia Dbndd2 35
  • 80.8 (n)
  • 79.11 (a)
Dbndd2 16
Dbndd2 36
  • 83 (a)
(Pan troglodytes)
Mammalia DBNDD2 35
  • 98.97 (n)
  • 98.07 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Dbndd2 35
  • 80.59 (n)
  • 81.01 (a)
(Monodelphis domestica)
Mammalia DBNDD2 36
  • 71 (a)
(Gallus gallus)
Aves DBNDD2 35
  • 60.75 (n)
  • 52.63 (a)
  • 46 (a)
(Anolis carolinensis)
Reptilia DBNDD2 36
  • 42 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.10760 35
African clawed frog
(Xenopus laevis)
Amphibia MGC53635 35
(Danio rerio)
Actinopterygii DBNDD2 36
  • 30 (a)
(Zea mays)
Liliopsida Zm.17524 35
Species with no ortholog for DBNDD2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DBNDD2 Gene

Gene Tree for DBNDD2 (if available)
Gene Tree for DBNDD2 (if available)

Paralogs for DBNDD2 Gene

Paralogs for DBNDD2 Gene

(1) SIMAP similar genes for DBNDD2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with DBNDD2: view

Variants for DBNDD2 Gene

Variation tolerance for DBNDD2 Gene

Gene Damage Index Score: 0.77; 16.22% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for DBNDD2 Gene

Disorders for DBNDD2 Gene

Relevant External Links for DBNDD2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for DBNDD2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DBNDD2 Gene

Publications for DBNDD2 Gene

  1. Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1. (PMID: 16618118) Yin H. … Kuret J. (Biochemistry 2006) 2 3 4 67
  2. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3
  3. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PMID: 16712791) Wang A.G. … Kim N.S. (Biochem. Biophys. Res. Commun. 2006) 3
  4. Identification of genes related to Parkinson's disease using expressed sequence tags. (PMID: 17213182) Kim J.M. … Kim N.S. (DNA Res. 2006) 3
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for DBNDD2 Gene

Sources for DBNDD2 Gene