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Aliases & Descriptions for DBNDD2
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases C20orf35 2 , 3 CK1BP 2 HSMNP1 1 , 2 , 3 , 5 OTTHUMP00000031115 2 OTTHUMP00000031116 2 OTTHUMP00000031117 2 OTTHUMP00000031118 2 OTTHUMP00000031119 2 OTTHUMP00000031120 2
Descriptions SCF apoptosis response protein 1 2 casein kinase-1 binding protein 2 chromosome 20 open reading frame 35 1 dysbindin (dystrobrevin binding protein 1) domain containing 2 2
Search outside databases for aliases for DBNDD2 genePrevious GC identifer: GC20P043426
Summaries for DBNDD2 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Gene Wiki entry for DBNDD2
Genomic Location for DBNDD2
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the DBNDD2 gene Entrez Gene cytogenetic band: 20q13.12 Ensembl cytogenetic band: 20q13.12 HGNC cytogenetic band: 20q13.12 DBNDD2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 20 GeneLoc Exon Structure
GeneLoc location for GC20P043468:
(about GC identifiers )
Start:
43,468,085 bp from pter
End:
43,472,664 bp from pter
Size:
4,580 bases
Orientation:
plus strand
RefSeq DNA sequence: NC_000020.9 NT_011362.9 Proteins for DBNDD2
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9 (See
protein sequence )Recommended Name: Dysbindin domain-containing protein 2 Size : 261 amino acids; 27856 Da
Secondary accessions : Q9BQZ0 Q9BVL1 Q9H1F6 Q9NWZ0 Q9NY07 Q9NZ31Alternative splicing : 2 isoforms : Q9BQY9-1 Q9BQY9-2
REFSEQ proteins (6 alternative transcripts):
NP_001041686.1 NP_001041687.1 NP_001041688.1 NP_001041689.1 NP_001041690.1 NP_001041691.1 ENSEMBL proteins: ENSP00000361802 ENSP00000361807 ENSP00000361797 ENSP00000354250 ENSP00000349822 ENSP00000361808 ENSP00000361795 ENSP00000361805 Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: DBNDD2 1 Gene Ontology (GO) cellular component term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0005737 cytoplasm
IEA --
About this table Antibodies for DBNDD2: Assays for DBNDD2:
Protein
Domains/ Families for DBNDD2(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q9BQY9 ProtoNet protein and cluster: Q9BQY9
UniProtKB/Swiss-Prot: DBND2_HUMAN, Q9BQY9 Similarity : Belongs to the dysbindin family
Gene Function for DBNDD2
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
from Invitrogen ,
Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 7 ): NM_001048221 Applied Biosystems Silencer ® siRNAs for DBNDD2 Sigma-Aldrich siRNA for DBNDD2 Sigma-Aldrich shRNA for DBNDD2 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 6 ): NM_001048221                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 6 ): NM_001048221                                  untagged cDNA clones in CMV expression vector (see all 7 ): AL591714  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_001048225 1 Gene Ontology (GO) molecular function term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding
IEA --
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Pathways & Interactions for DBNDD2
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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1 Interacting protein for DBNDD2 (Q9BQY9 2 ) via UniProtKB, MINT, and/or STRING About this table
Drugs & Compounds for DBNDD2 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for DBNDD2
Transcripts for DBNDD2(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
Tagged/untagged cDNA clones from
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 7 ): NM_001048221 Sigma-Aldrich siRNA for DBNDD2 Sigma-Aldrich shRNA for DBNDD2 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_001048221 NM_001048222 NM_001048223 NM_001048224 NM_001048225 NM_001048226
REFSEQ mRNAs for DBNDD2 gene (6 alternative transcripts): NM_001048221.1 NM_001048222.1 NM_001048223.1 NM_001048224.1 NM_001048225.1 NM_001048226.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001048222 NM_001048223 NM_001048224 NM_001048226
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 6 ): NM_001048221                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 6 ): NM_001048221                                  untagged cDNA clones in CMV expression vector (see all 7 ): AL591714  
Additional cDNA sequence: AF220191.1 AJ276469.1 AK000531.1 AK075264.1 AK172738.1 AK309429.1 AL591565.1 AL591714.1 AY113697.1 BC001105.2 BC012818.2 BC048286.1 CR595212.1 CR596680.1 CR599811.1 CR600511.1 CR604473.1 CR605916.1 CR607560.1 CR610357.1 CR616955.1 CR618022.1 CR618346.1 CR622797.1 CR623013.1 CR623457.1 CR624106.1 CR625786.1
24/33 DOTS entries (see all 33
): DT.415832 DT.97853151 DT.100810477 DT.100697234 DT.444894 DT.100030231 DT.95364384 DT.120830931 DT.91756231 DT.100810474 DT.120830980 DT.99931902 DT.120830883 DT.95364385 DT.91756220 DT.95316815 DT.100797177 DT.100797182 DT.102832295 DT.91756228 DT.120830958 DT.92435658 DT.95364387 DT.97855931
24/656 AceView cDNA sequences (see all 656
):BI758096 AL532475 BM761997 BI822128 BU527390 CR600511 AI540683 BQ011749 CR604473 BP336561 BI518572 CR622797 BM505581 CR596680 BU556476 AA977070 CA503318 AW341688 AA584422 BU729212 AA737834 AI149677 F04287 BU733851
highest scoring ESTs for DBNDD2 :AI928870 AA043132 AA199636 AA324861 AA425399 AA425509 AA425852 AA458887 AA459078 AA478016
Unigene Cluster for DBNDD2: Dysbindin (dystrobrevin binding protein 1) domain containing 2 Hs.655055 [show with all ESTs ] Unigene Representative Sequence: NM_033542 GeneLoc Exon Structure 8 Ensembl transcripts including schematic representations : ENST00000372717
ENST00000372722
ENST00000372712
ENST00000360981
ENST00000357275
ENST00000372723
ENST00000372710
ENST00000372720
Expression for DBNDD2
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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DBNDD2 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for DBNDD2 1 / 2 / 3
3 probe-sets matching DBNDD2 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: --SOURCE GeneReport for Unigene cluster: Hs.655055
Orthologs for DBNDD2
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for DBNDD2 gene from 5/9 species (see all 9
)
About this table Species with no ortholog for DBNDD2 ENSEMBL Gene Tree for DBNDD2 Paralogs for DBNDD2 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for DBNDD2 gene DTNBP1 2
SNPs/Variants for DBNDD2 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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The following additional 216 SNP(s) have been
found in Applied Biosystems data source:(Click
for
Applied Biosystems TaqMan ® Genotyping Assay ) HapMap Linkage Disequilibrium images for DBNDD2 (up to first 250kb)
Disorders & Mutations for DBNDD2
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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OMIM: 611453
Medical News for DBNDD2 (Possibly Related Articles in
Doctor's Guide )
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--
Publications for DBNDD2 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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10/14 PubMed articles for DBNDD2 gene (see all 14
):
Search for DBNDD2
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing DBNDD2
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing DBNDD2
(According to HUGE )
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--
Specialized Databases showing DBNDD2 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for DBNDD2 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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