DBNDD1 Gene
protein-coding GIFtS: 41
GCID: GC16M090071
|
|
dysbindin (dystrobrevin binding protein 1) domain containing...
| |
Aliases
for DBNDD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Dysbindin (Dystrobrevin Binding Protein 1) Domain Containing 11 2 | | FLJ125821 | | MGC31011 | | Dysbindin Domain-Containing Protein 12 |
| External Ids: | HGNC: 284551 | Entrez Gene: 790072 | Ensembl: ENSG000000032497 | UniProtKB: Q9H9R93 | | ORGUL members: | |
|---|
| NONCODE:n339352 | |
Export aliases for DBNDD1 gene to outside databasesPrevious GC identifers: GC16M088599 GC16M075763
|---|
Summaries
for DBNDD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for DBNDD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010542.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DBNDD1 gene promoter:
GR SREBP-1a SREBP-1c GR-beta GR-alpha LCR-F1 SREBP-1b
Other transcription factors
Search SABiosciences Chromatin IP Primers for DBNDD1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DBNDD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q24.3 Ensembl cytogenetic band: 16q24.3 HGNC cytogenetic band: 16q24.3DBNDD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M090071: view genomic region
(about GC identifiers)
Start:
|
90,071,273 bp from pter |
End:
|
90,086,536 bp from pter |
Size:
|
15,264 bases |
Orientation:
|
minus strand |
|
Proteins
for DBNDD1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DBND1_HUMAN, Q9H9R9 (See
protein sequence)Recommended Name: Dysbindin domain-containing protein 1 Size: 158 amino acids; 17042 Da
Secondary accessions: B4DQS3 Q69YT2 Q9BW25Alternative splicing: 3 isoforms: Q9H9R9-1 Q9H9R9-2 Q9H9R9-3 Explore the universe of human proteins at neXtProt for DBNDD1: NX_Q9H9R9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H9R9
DBNDD1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001036075.1 NP_076948.2
ENSEMBL proteins: ENSP00000306407 ENSP00000002501 ENSP00000376699 ENSP00000457625 ENSP00000456573
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
DBNDD1 for ontologies About GeneDecksing
DBNDD1 Antibody Products:
Assay Products for DBNDD1: |
Protein
Domains /
Families
for DBNDD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DBNDD1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9H9R9ProtoNet protein and cluster: Q9H9R9 UniProtKB/Swiss-Prot: DBND1_HUMAN, Q9H9R9Similarity: Belongs to the dysbindin family |
Function
for DBNDD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): DBNDD1 (NM_001042610) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DBNDD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DBNDD1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DBNDD1 |
|
Pathways & Interactions
for DBNDD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DBNDD1
|
Drugs & Compounds
for DBNDD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DBNDD1
Search CenterWatch for drugs/clinical trials and news about DBNDD1 / DBND1
|
Transcripts
for DBNDD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DBNDD1 gene (2 alternative transcripts): NM_001042610.1 NM_024043.2 Unigene Cluster for DBNDD1: Dysbindin (dystrobrevin binding protein 1) domain containing 1 Hs.301394 [show with all ESTs]Unigene Representative Sequence: AK0965077 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000304733(uc002fqe.1) ENST00000002501(uc002fqf.1 uc002fqg.1)
ENST00000566725 ENST00000392973 ENST00000568838 ENST00000568662 ENST00000568330
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): DBNDD1 (NM_001042610) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DBNDD1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DBNDD1 |
Additional cDNA sequence: AK022644.1 AK090696.1 AK090965.1 AK096507.1 AK298932.1 AK308737.1 AL713678.1 BC000700.2 10 DOTS entries: DT.100782491 DT.100782490 DT.214910 DT.120721037 DT.100782494 DT.97759896 DT.92425551 DT.120720949 DT.92425552 DT.92425549 24/119 AceView cDNA sequences (see all 119): AW630072 BF196967 AW613841 BU183018 BC000700 BG113111 AL713678 AI087811 BM712235 AK090696 AA991580 CD676065 CR594535 NM_024043 AX746579 BX279734 BM715499 AA806459 BI094047 BQ893562 AK096507 BE905380 AA485809 BI224259
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for DBNDD1 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | - | | - | | - | | - | | | | - | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | - | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for DBNDD1
|
Expression
for DBNDD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DBNDD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See DBNDD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DBNDD1
SOURCE GeneReport for Unigene cluster: Hs.301394
SABiosciences Custom PCR Arrays for DBNDD1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DBNDD1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DBNDD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DBNDD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DBNDD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DBNDD1 |
Orthologs
for DBNDD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for DBNDD1 gene from 4/10 species (see all 10) About this table
ENSEMBL Gene Tree for DBNDD1 (if available)
TreeFam Gene Tree for DBNDD1 (if available) |
Paralogs
for DBNDD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for DBNDD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DBNDD1 (90071273 - 90086536 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for DBNDD1
2 CNVs: 72708 0200
2 Indels: 25760 25759 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DBNDD1 |
|
Disorders
/ Diseases
for DBNDD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for DBNDD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DBNDD1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with DBNDD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Variation in the dysbindin gene and normal cognitive function in three independent population samples. (PubMed id 19077176)1 Luciano M....Payton A. (2009)
- Genome-Wide Association Study of Tanning Phenotype in a Population of European Ancestry. (PubMed id 19340012)1 Nan H....Han J. (2009)
- TRIM32 is an E3 ubiquitin ligase for dysbindin. (PubMed id 19349376)1 Locke M.... Blake D.J. (2009)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for DBNDD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DBNDD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DBNDD1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DBNDD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DBNDD1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for DBNDD1 gene:
Search GeneIP for patents involving DBNDD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DBNDD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DBNDD1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DBNDD1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DBNDD1 | | | OriGene Protein Over-expression Lysate for DBNDD1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DBNDD1 | | OriGene 3'-UTR Clone for DBNDD1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DBNDD1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for DBNDD1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for DBNDD1 | | OriGene Custom Protein Services for DBNDD1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DBNDD1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DBNDD1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DBNDD1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DBNDD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DBNDD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DBNDD1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for DBNDD1 |
| |  |  |  |  | | | | | | Recombinant Protein for DBNDD1 |
|
 |
 |
 |
 | | | DBNDD1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DBNDD1 |
|  |  |  | | | | Search ThermoFisher Antibodies for DBNDD1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DBNDD1 |
|
|
|
|
GeneCards Homepage -
Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
View Random Gene
|
Category
|
|
|
von Willebrand factor
|
| GIFtS Group |
|
Developed at the Crown Human Genome Center,
Department of Molecular Genetics,
the Weizmann Institute of Science
Copyright © 1996-2013
, Weizmann Institute of Science. All Rights Reserved.
hostname: 356977-web1.xennexinc.com
index build: 100 solr: 1.4
|
