Aliases for DBH Gene
External Ids for DBH Gene
Previous GeneCards Identifiers for DBH Gene
The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. [provided by RefSeq, Jul 2008]
GeneCards Summary for DBH Gene
DBH (Dopamine Beta-Hydroxylase) is a Protein Coding gene. Diseases associated with DBH include Dopamine Beta-Hydroxylase Deficiency and Pure Autonomic Failure. Among its related pathways are Biogenic Amine Synthesis and Sympathetic Nerve Pathway (Neuroeffector Junction). GO annotations related to this gene include copper ion binding and L-ascorbic acid binding. An important paralog of this gene is MOXD1.
UniProtKB/Swiss-Prot for DBH Gene
Conversion of dopamine to noradrenaline.