V3 here soon-try beta now
Gene Search (GeneCards Home) | GeneCards Guide | User Feedback | Terms of Use | Notice about third-party sites
 

DBF4 Gene

protein-coding   GIFtS: 59

GC07P087343
DBF4 homolog (S. cerevisiae)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases
ASK 1, 2, 3
ASKL1 5
CHIF 2
DBF4A 1, 2, 3
DBF4B 5
DRF1 5
OTTHUMP00000161661 2
ZDBF1 1, 2, 3
chif 1
Descriptions
Activator of S phase kinase 2, 3
Chiffon homolog A 3
DBF4 homolog (S. cerevisiae) 2
DBF4-type zinc finger-containing protein 1 3
chiffon homolog 2
zinc finger, DBF-type containing 1 2
External Ids
HGNC: 173641
Entrez Gene: 109262
UniProtKB: Q9UBU73
Ensembl: ENSG000000066347
Search outside databases for aliases for DBF4 gene

Previous GC identifer: GC07P087151

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: DBF4A_HUMAN, Q9UBU7
Function: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central
role in DNA replication and cell proliferation. Required for progression of S phase. The complex
CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved
in regulating the initiation of DNA replication during cell cycle

Gene Wiki entry for DBF4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the DBF4 gene  

Entrez Gene cytogenetic band: 7q21.3   Ensembl cytogenetic band:  7q21.12   HGNC cytogenetic band: 7q21.3

DBF4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P087343:     (about GC identifiers)

Start:
87,343,480 bp from pter
End:
87,376,792 bp from pter
Size:
33,313 bases
Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 86,836,862-86,870,174     
RefSeq DNA sequence:
NC_000007.12  NT_007933.14  NT_079595.2  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: DBF4A_HUMAN, Q9UBU7 (See protein sequence)
Recommended Name: Protein DBF4 homolog A  
Size: 674 amino acids; 76858 Da
Subunit: Forms a complex with CDC7. Note that CDC7 forms distinct complex either with DBF4A or
DBF4B. Such complexes are stable upon replication stress. Interacts with MEN1, MCM2, ORC2L, ORC4L
and ORC6L
Subcellular location: Nucleus
Secondary accessions: A4D1D8 A8K954 O75226 Q75MS6 Q75N01 Q9Y2M6
Alternative splicing: 2 isoforms:  Q9UBU7-1   Q9UBU7-2   

Post-translational modifications:

  • Phosphorylated upon DNA damage, probably by ATM or ATR1
  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_006707.1  

    ENSEMBL proteins: 
    ENSP00000265728 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (DBF4)
    Human Recombinant Proteins from Abnova (DBF4)
                  OriGene Purified Recombinant Human Protein: DBF4 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622 intracellular IEA--
    GO:0005634 nucleus IEA--
    GO:0005654 nucleoplasm EXP10846177 15226314 15707391
    About this table

    Antibodies for DBF4: 
    Invitrogen Antibodies for DBF4
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for DBF4
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (DBF4), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (DBF4)
    Novus Biologicals Antibodies for DBF4

    Assays for DBF4: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    2 InterPro domains/families:
     IPR006572 Znf_DBF
     IPR001357 BRCT


       GeneDecks  DBF4 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q9UBU7

    ProtoNet protein and cluster: Q9UBU7

    UniProtKB/Swiss-Prot: DBF4A_HUMAN, Q9UBU7
    Similarity: Contains 2 BRCT domains
    Similarity: Contains 1 DBF4-type zinc finger

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (DBF4)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (DBF4)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006716

                  Applied Biosystems Silencer® siRNAs for DBF4

                  Sigma-Aldrich siRNA and siRNA Panels for DBF4  
                         Sigma-Aldrich shRNA Panels and shRNA for DBF4  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for DBF4
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_006716
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_006716
                                     untagged cDNA clone in CMV expression vector: NM_006716 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_006716

    UniProtKB/Swiss-Prot: DBF4A_HUMAN, Q9UBU7
    Function: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central
    role in DNA replication and cell proliferation. Required for progression of S phase. The complex
    CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved
    in regulating the initiation of DNA replication during cell cycle
    Induction: Induced in G1 phase at low level, increased during G1-S phase and remain high during S
    and G2-M phase

    5 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676 nucleic acid binding IEA--
    GO:0005515 protein binding IPI15231747
    GO:0008047 enzyme activator activity TAS10373557
    GO:0008270 zinc ion binding IEA--
    GO:0046872 metal ion binding IEA--
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Millipore Pathway for DBF4
     Cell cycle Start of DNA replication in early S phase

       GeneDecks  DBF4 for the pathways selected above  
    About GeneDecksing

    1 Kegg Pathway  (Kegg details for DBF4):
     hsa04110 Cell cycle

       GeneDecks  DBF4 for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  DBF4 


    5/45 Interacting proteins for DBF4 (Q9UBU71, 2 ENSP000002657283) via UniProtKB, MINT, and/or STRING (see all 45 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LSM8O957771EBI-372690, EBI-347779
    CHAF1AQ131112MINT-2842119
    CDC7ENSP000003594433STRING (score=.999)
    MCM2ENSP000002650563STRING (score=.999)
    MCM3ENSP000002298543STRING (score=.999)
    About this table

    3 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000082 G1/S transition of mitotic cell cycle TAS10373557
    GO:0006260 DNA replication TAS10373557
    GO:0007049 cell cycle IEA--
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for DBF4

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (DBF4)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (DBF4)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006716

                  Sigma-Aldrich siRNA and siRNA Panels for DBF4  
                         Sigma-Aldrich shRNA Panels and shRNA for DBF4  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_006716  

    REFSEQ mRNAs for DBF4 gene: 

    NM_006716.3   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_006716  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_006716
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_006716
                                     untagged cDNA clone in CMV expression vector: NM_006716 

    Additional cDNA sequence: 

    AB028069.1 AB028070.1 AF160249.1 AF160876.1 AK022969.1 AK292569.1 AK302010.1 AK303175.1 
    BC014909.1 BC022811.1 BC035632.1 BC036045.1 BC047693.1 CR606603.1 

    9 DOTS entries:

    DT.455675  DT.100778051  DT.100697787  DT.100817855  DT.91662416  DT.121250434  DT.100817857  DT.100817860 
    DT.121250409 

    24/145 AceView cDNA sequences (see all 145 ):

    BM854170 CB108960 BG724408 AI923577 BU175218 AF160876 AA262811 BM761973 
    AI149615 AA825820 BM785927 BM847871 AK022969 BC035632 AA287837 BM474158 
    NM_006716 AI539636 BU160067 CB123764 AV728361 AL548911 AL560180 AI630093 

    highest scoring ESTs for DBF4:

    AB028069 AA262811 AA282071 AA282335 AA451820 AA454056 AA609274 AA628515 AA648308 AA825820 

    Unigene Cluster for DBF4:

    DBF4 homolog (S. cerevisiae)
    Hs.485380  [show with all ESTs]
    Unigene Representative Sequence: NM_006716


    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for DBF4

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b
    SP1:                                                                                    
    SP2:                                                                    -               
    SP3:        -                                                                           
    SP4:        -     -     -     -     -     -     -     -                                 

    About this scheme

    ECgene alternative splicing isoforms for DBF4

    1 Ensembl transcript including schematic representation:
    ENST00000265728  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    DBF4 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for DBF4

    1 / 2 / 3

    3 probe-sets matching DBF4 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    31865_at2, 3 U95-A 2 1.00 0.75 1.00 1.00 AB028069 1.00 1.00 1.00 1

    204244_s_at2, 3 U133-A 3 1.00 0.80 -- -- NM_006716 0.60 1.00 0.82 1

    204244_s_at2 U133Plus2 3 1.00 0.80 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: ATTCTGGTCT

    SOURCE GeneReport for Unigene cluster: Hs.485380

    UniProtKB/Swiss-Prot: DBF4A_HUMAN, Q9UBU7
    Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells
    lines

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for DBF4 gene from 5/7 species (see all 7 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    DBF41   -- DBF4 homolog (S. cerevisiae) 88.66(n)
    82.91(a)
    475219  XM_532451.2  XP_532451.2 
    chimpanzee
    (Pan troglodytes)
    DBF41   -- DBF4 homolog (S. cerevisiae) 99.85(n)
    99.7(a)
    472668  XM_528041.2  XP_528041.2 
    cow
    (Bos taurus)
    DBF41   -- DBF4 homolog (S. cerevisiae) 91.72(n)
    92.16(a)
    510916  NM_001075476.1  NP_001068944.1 
    rat
    (Rattus norvegicus)
    Dbf41   -- DBF4 homolog (S. cerevisiae) 78.03(n)
    69.08(a)
    312046  XM_231388.4  XP_231388.4 
    mouse
    (Mus musculus)
    Dbf41, 5 55
    DBF4 homolog (S. cerevisiae)1, 5 77.09(n)1
    67.98(a)1
    272141  NM_013726.21  NP_038754.11 
     AA5452175  AJ0031325  (see all 23)
    About this table        Species with no ortholog for DBF4

    ENSEMBL Gene Tree for DBF4
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for DBF4 gene
    DBF4B2  

    Pseudogenes
    3 related pseudogenes


    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/116 NCBI SNPs in DBF4 are shown (see all 116 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 44)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 7 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    --
    rs20410491,2
    A,C,F,H,O87375113(-) TTCGAT/CGTATT 1 R/H mis1 ese313Minor allele frequency- C:0.05NA EA MN EU WA 1348
    rs102336821,2
    A,C,F,H87376035(+) ACTTTA/GATAAT 1 -- ut315Minor allele frequency- G:0.16EA NA 312
    --
    rs69776871,2
    C,F,H87375963(+) AGGAAG/AGACTT 1 -- ut31 trp37Minor allele frequency- A:0.30EU EA WA NA 562
    rs102630741,2
    C,F,H87375999(+) TTTATC/GTGCTA 1 -- ut31 ese37Minor allele frequency- G:0.07EU EA WA NA 556
    --
    rs14767031,2
    F87352344(-) AGTATT/ATGCAG 1 N/Y mis1 ese31Minor allele frequency- A:0.40MN 184
    rs69775041,2
    H87375866(+) CATCAG/TAAATA 1 -- ut314Minor allele frequency- T:0.00EU EA WA 406
    --
    rs78120241,2
    H87371655(+) CACACC/GTAAAA 1 P/R mis1 ese34Minor allele frequency- G:0.00EU EA WA 402
    --
    rs171467871,2
    F87375677(+) ATTTGC/GTTTGT 1 -- ut313Minor allele frequency- G:0.03NA 142
    --
    rs126667421,2
    C,F87375126(+) GTGAAA/GATAAT 1 K/K syn13Minor allele frequency- G:0.03NA 140
    rs14767041,2
    F87352280(-) TCCTTC/TTTATT 1 K/K syn1 trp31Minor allele frequency- T:0.42MN 184
    About this table

    HapMap Linkage Disequilibrium images for DBF4 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 611661

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/34 PubMed articles for DBF4 gene (see all 34 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 10926 HGNC: 17364 AceView: ASK Ensembl:ENSG00000006634 euGenes: HUgn10926
    ECgene: DBF4 H-InvDB: DBF4
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

      --
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for DBF4:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for DBF4-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for DBF4 Antibodies for DBF4
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for DBF4 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (DBF4)
     Antibodies (DBF4)
     Chimera RNAi (DBF4)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (DBF4)
     Antibodies (DBF4)
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     Search Tocris compounds for DBF4




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for DBF4

    GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

    Random Gene From GIFtS : about GIFtS

    Gene Index:   3   5   A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P   Q   R   S   T   U   V   W   X   Y   Z

    Developed at the Crown Human Genome Center & Weizmann Institute of Science



    The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
    DBF4 Gene at Home site.
    Version 2.41.1
    server5.xennexinc.com