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Aliases for DAW1 Gene

Aliases for DAW1 Gene

  • Dynein Assembly Factor With WDR Repeat Domains 1 2 3
  • Outer Row Dynein Assembly Protein 16 Homolog 3 4
  • WD Repeat-Containing Protein 69 3 4
  • WD Repeat Domain 69 2 3
  • WDR69 3 4
  • Outer Row Dynein Assembly 16 Homolog (Chlamydomonas) 2
  • Outer Row Dynein Assembly 16 Homolog 3
  • ODA16 3

External Ids for DAW1 Gene

Previous Symbols for DAW1 Gene

  • WDR69

Summaries for DAW1 Gene

GeneCards Summary for DAW1 Gene

DAW1 (Dynein Assembly Factor With WDR Repeat Domains 1) is a Protein Coding gene. An important paralog of this gene is ATG16L1.

UniProtKB/Swiss-Prot for DAW1 Gene

  • May play a role in axonemal outer row dynein assembly.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DAW1 Gene

Genomics for DAW1 Gene

Genomic Location for DAW1 Gene

Start:
227,871,054 bp from pter
End:
227,924,344 bp from pter
Size:
53,291 bases
Orientation:
Plus strand

Genomic View for DAW1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DAW1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DAW1 Gene

No data available for Regulatory Elements for DAW1 Gene

Proteins for DAW1 Gene

  • Protein details for DAW1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N136-DAW1_HUMAN
    Recommended name:
    Dynein assembly factor with WDR repeat domains 1
    Protein Accession:
    Q8N136
    Secondary Accessions:
    • Q6ZRY1
    • Q8N776

    Protein attributes for DAW1 Gene

    Size:
    415 amino acids
    Molecular mass:
    45777 Da
    Quaternary structure:
    • Interacts with IFT46.

    Alternative splice isoforms for DAW1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DAW1 Gene

Proteomics data for DAW1 Gene at MOPED

Post-translational modifications for DAW1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for DAW1 Gene

No data available for DME Specific Peptides for DAW1 Gene

Domains for DAW1 Gene

Gene Families for DAW1 Gene

HGNC:
  • WDR :WD repeat domain containing

UniProtKB/Swiss-Prot:

DAW1_HUMAN
Family:
  • Belongs to the WD repeat WDR69 family.:
    • Q8N136
Similarity:
  • Contains 8 WD repeats.:
    • Q8N136
genes like me logo Genes that share domains with DAW1: view

Function for DAW1 Gene

Molecular function for DAW1 Gene

UniProtKB/Swiss-Prot Function: May play a role in axonemal outer row dynein assembly.

Gene Ontology (GO) - Molecular Function for DAW1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with DAW1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for DAW1 Gene

Localization for DAW1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for DAW1 Gene

Cell projection, cilium.

Gene Ontology (GO) - Cellular Components for DAW1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005929 cilium IEA --
genes like me logo Genes that share ontologies with DAW1: view

Pathways for DAW1 Gene

SuperPathways for DAW1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for DAW1 Gene

None

No data available for Pathways by source for DAW1 Gene

Transcripts for DAW1 Gene

Unigene Clusters for DAW1 Gene

Dynein assembly factor with WDR repeat domains 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DAW1 Gene

No ASD Table

Relevant External Links for DAW1 Gene

GeneLoc Exon Structure for
DAW1
ECgene alternative splicing isoforms for
DAW1

Expression for DAW1 Gene

mRNA expression in normal human tissues for DAW1 Gene

mRNA differential expression in normal tissues according to GTEx for DAW1 Gene

This gene is overexpressed in Testis (20.1), Brain - Nucleus accumbens (basal ganglia) (5.2), and Brain - Caudate (basal ganglia) (4.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for DAW1 Gene

SOURCE GeneReport for Unigene cluster for DAW1 Gene Hs.424594

genes like me logo Genes that share expressions with DAW1: view

Orthologs for DAW1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for DAW1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia WDR69 36
  • 99.36 (n)
  • 99.52 (a)
WDR69 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia DAW1 36
  • 90.36 (n)
  • 93.49 (a)
DAW1 37
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DAW1 36
  • 89.88 (n)
  • 92.53 (a)
DAW1 37
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Daw1 16
Daw1 37
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DAW1 37
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 84 (a)
OneToMany
-- 37
  • 84 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Daw1 36
  • 84.42 (n)
  • 89.88 (a)
chicken
(Gallus gallus)
Aves DAW1 37
  • 75 (a)
OneToOne
WDR69 36
  • 76.89 (n)
  • 79.71 (a)
lizard
(Anolis carolinensis)
Reptilia DAW1 37
  • 74 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.12681 36
tropical clawed frog
(Silurana tropicalis)
Amphibia daw1 36
  • 73.09 (n)
  • 80 (a)
MGC76247 36
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2611 36
zebrafish
(Danio rerio)
Actinopterygii daw1 36
  • 67.82 (n)
  • 72.41 (a)
daw1 37
  • 71 (a)
OneToOne
Dr.15604 36
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009574 36
  • 31.04 (n)
  • 15.38 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7568 36
  • 51.49 (n)
  • 43.37 (a)
CG7568 37
  • 38 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RSA4 37
  • 21 (a)
OneToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4284 36
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9620 37
  • 67 (a)
OneToOne
Species with no ortholog for DAW1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DAW1 Gene

ENSEMBL:
Gene Tree for DAW1 (if available)
TreeFam:
Gene Tree for DAW1 (if available)

Paralogs for DAW1 Gene

genes like me logo Genes that share paralogs with DAW1: view

Variants for DAW1 Gene

Sequence variations from dbSNP and Humsavar for DAW1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1016418 -- 227,880,046(+) CATTG(A/G)GTTTT intron-variant
rs1112484 -- 227,919,785(-) GATTG(G/T)GCTGA intron-variant
rs1524025 -- 227,888,736(-) CATTT(C/T)ACAAA intron-variant
rs1524026 -- 227,877,929(-) TGTAC(A/G)TTTGA intron-variant
rs1533960 -- 227,918,763(-) GGGTG(G/T)GGATA intron-variant

Relevant External Links for DAW1 Gene

HapMap Linkage Disequilibrium report
DAW1

No data available for Structural Variations from Database of Genomic Variants (DGV) for DAW1 Gene

Disorders for DAW1 Gene

No disorders were found for DAW1 Gene.

No data available for UniProtKB/Swiss-Prot for DAW1 Gene

Publications for DAW1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  4. Oda16/Wdr69 is essential for axonemal dynein assembly and ciliary motility during zebrafish embryogenesis. (PMID: 20568242) Gao C. … Mitchell D.R. (Dev. Dyn. 2010) 2 3
  5. A unified taxonomy for ciliary dyneins. (PMID: 21953912) Hom E.F. … King S.M. (Cytoskeleton (Hoboken) 2011) 2 3

Products for DAW1 Gene

Sources for DAW1 Gene

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