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DARS2 Gene

protein-coding GIFtS: 57

GC01P172060

aspartyl-tRNA synthetase 2, mitochondrial
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ASPRS ^²
AspRS ^³
EC 6.1.1.12 ^³
FLJ10514 ^¹, ²
LBSL ^²
MT-ASPRS ^²
OTTHUMP00000032692 ^²
RP3-383J4.2 ^²

Descriptions
ASPRS. LBSL ^⁵
Aspartate--tRNA ligase ^³
aspartate tRNA ligase 2, mitochondrial ^²
aspartyl-tRNA synthetase 2, mitochondrial ^²

External Ids
HGNC: 25538¹
Entrez Gene: 55157²
UniProtKB: Q6PI48³
Ensembl: ENSG00000117593⁷

Search outside databases for aliases for DARS2 gene

Previous GC identifer: GC01P170526

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DARS2 gene

Entrez Gene cytogenetic band: 1q25.1 Ensembl cytogenetic band: 1q25.1 HGNC cytogenetic band: 1q25.1

DARS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P172060: (about GC identifiers)

Start:	172,060,581 bp from pter
End:	172,094,305 bp from pter
Size:	33,725 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000001.9 NT_004487.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: SYDM_HUMAN, Q6PI48 (See protein sequence)

Recommended Name: Aspartyl-tRNA synthetase, mitochondrial precursor

Size: 645 amino acids; 73563 Da

Subunit: Homodimer

Subcellular location: Mitochondrion matrix

REFSEQ proteins: NP_060592.2

ENSEMBL proteins:

ENSP00000355086 ENSP00000239457

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (DARS2)
	Human Recombinant Proteins from Abnova (DARS2)

OriGene Purified Recombinant Human Protein: DARS2

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005739	mitochondrion	IEA	--
GO:0005759	mitochondrial matrix	IEA	--

About this table

Antibodies for DARS2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for DARS2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (DARS2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (DARS2)
	Novus Biologicals Antibodies for DARS2

Assays for DARS2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q6PI48

ProtoNet protein and cluster: Q6PI48

4 Blocks protein families:

IPB002312 Aspartyl-tRNA synthetase signature

IPB004115 GAD domain

IPB004364 tRNA synthetase

IPB004365 OB-fold nucleic acid binding domain

UniProtKB/Swiss-Prot: SYDM_HUMAN, Q6PI48

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DARS2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DARS2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_018122

Applied Biosystems Silencer® siRNAs for DARS2

Sigma-Aldrich siRNA for DARS2

Sigma-Aldrich shRNA for DARS2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for DARS2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_018122
Myc/DDK tagged cDNA clone in CMV expression vector: NM_018122
untagged cDNA clones in CMV expression vector (see all 3): AL833633

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_018122

UniProtKB/Swiss-Prot: SYDM_HUMAN, Q6PI48

Catalytic activity: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)

Enzyme Number (IUBMB): EC 6.1.1.12

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0003676	nucleic acid binding	IEA	--
GO:0004815	aspartate-tRNA ligase activity	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0016874	ligase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for DARS2 (Your Favorite Gene powered by Ingenuity)

Aminoacyl-tRNA Biosynthesis
Alanine and Aspartate Metabolism

GeneDecks DARS2 for the pathways selected above

About GeneDecksing

5/17 Interacting proteins for DARS2 (ENSP00000355086³) via UniProtKB, MINT, and/or STRING (see all 17 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ADSS	ENSP00000355493³	STRING (score=.906)
ADSSL1	ENSP00000333019³	STRING (score=.9)
ASNS	ENSP00000175506³	STRING (score=.9)
ACY3	ENSP00000255082³	STRING (score=.899)
ASS1	ENSP00000361471³	STRING (score=.899)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006422	aspartyl-tRNA aminoacylation	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for DARS2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DARS2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DARS2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_018122

Sigma-Aldrich siRNA for DARS2

Sigma-Aldrich shRNA for DARS2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_018122

REFSEQ mRNAs for DARS2 gene:

NM_018122.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_018122

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_018122
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_018122
                                 untagged cDNA clones in CMV expression vector (see all 3): AL833633

Additional cDNA sequence:

AK001376.1 AK022754.1 AK290873.1 AL833633.1 BC045173.2

12 DOTS entries:

DT.95272513 DT.313079 DT.95366867 DT.102842494 DT.121423412 DT.121423403 DT.95272512 DT.121423394

DT.121423458 DT.121423482 DT.95272510 DT.99970861

24/165 AceView cDNA sequences (see all 165 ):

BQ059324 CA337391 BE263867 AL701998 AI022771 BQ427584 NM_018122 BQ688158

AU125913 AL833633 BU194090 AI022773 AI637676 AU126045 AA642983 BG254491

BM473527 CA453987 AA775023 BM770614 AU125713 BI088368 BQ437431 AI378374

highest scoring ESTs for DARS2:

AI126802 AA284708 AA287138 AA514968 AA642983 AA693657 AA775023 AA805701 AA829971 AA852950

Unigene Cluster for DARS2:

Aspartyl-tRNA synthetase 2, mitochondrial

Hs.647707 [show with all ESTs]

Unigene Representative Sequence: NM_018122

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for DARS2

ExUns:	1	^	2	^	3	^	4	^	5	^	6a	·	6b	^	7	^	8	^	9	^	10a	·	10b	^	11a	·	11b	^	12	^	13	^	14	^	15a	·	15b	·	15c	^	16	^	17a	·	17b
SP1:
SP2:																	-		-
SP3:																													-
SP4:																															-
SP5:																																			-		-		-

About this scheme

ECgene alternative splicing isoforms for DARS2

2 Ensembl transcripts including schematic representations:

ENST00000361951 ENST00000239457

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

DARS2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DARS2

¹ / ² / ³

4 probe-sets matching DARS2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
64470_at²^{, 3}	U95-C	1	1.00	1.00	0.92	1.11	AI126802	1.00	1.00	1.00	1
86801_at²^{, 3}	U95-E	1	0.88	1.00	0.92	0.90	AA535724	0.60	1.00	0.82	1
218365_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI765051	0.80	1.00	0.91	1
218365_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TTTCTCATAC

SOURCE GeneReport for Unigene cluster: Hs.647707

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DARS2 gene from 5/18 species (see all 18 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DARS2¹	--	aspartyl-tRNA synthetase 2, mitochondrial	89.36(n) 87.01(a)	490337 XM_547457.2 XP_547457.2
chimpanzee (Pan troglodytes)	DARS2¹	--	aspartyl-tRNA synthetase 2, mitochondrial	99.43(n) 99.22(a)	469591 XM_524974.2 XP_524974.2
cow (Bos taurus)	DARS2¹	--	aspartyl-tRNA synthetase 2, mitochondrial	89.03(n) 86.99(a)	538772 XM_582590.3 XP_582590.2
rat (Rattus norvegicus)	Dars2¹	--	aspartyl-tRNA synthetase 2 (mitochondrial)	84.48(n) 85.83(a)	304919 NM_001034143.1 NP_001029315.1
mouse (Mus musculus)	Dars2^{1, 5}	1⁵	aspartyl-tRNA synthetase 2 (mitochondrial)^{1, 5}	84.6(n)¹ 85.69(a)¹	226539¹ NM_172644.3¹ NP_766232.1¹ AK030952⁵ AK033634⁵ (see all 26)

About this table Species with no ortholog for DARS2

ENSEMBL Gene Tree for DARS2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for DARS2 gene

KARS²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/155 NCBI SNPs in DARS2 are shown (see all 155 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 45)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs9425758^1,2	C,F	172093676(+)	`TTTGGT/CTAGGA`	1	--	ut3¹		3		NA	132
	rs35515638^1,2	C,F	172069231(+)	`CATGAA/GAATGC`	1	K/R	mis¹		5		NA EU EA WA	496
--	rs12084787^1,2	A	172093779(+)	`ACCCAA/GATAGT`	1	--	ut3¹		0	--	--	--	--
--	rs1535526^1,2	H	172094764(+)	`TTTAAG/ATTCTA`	1	--	ng3¹		3		EU EA	276
	rs2068871^1,2	C,F,H,O	172062792(+)	`AGGGTA/GTAACA`	1	--	int¹		12		EU EA WA	1256
	rs9425756^1,2	A,C,F,H	172083209(+)	`TCTCTC/TTCTTC`	1	--	int¹ trp³		4		EU EA WA	418
	rs2295366^1,2	A,C,F,H	172092315(+)	`GTCAGT/GTTTAG`	1	--	int¹		13		EA NA EU WA	1960
	rs6691327^1,2	A,C,F,H	172080071(+)	`TCATGT/GTGAAC`	1	--	int¹		8		EU EA WA	838
--	rs6425260^1,2	A,C,F,H	172062576(+)	`GAATGC/TATGGT`	1	--	int¹		4		EU EA WA	416
	rs7518130^1,2	A,C,F,H	172091990(+)	`TCACAA/TGATCA`	1	--	int¹		11		EU EA WA NA	980

About this table

HapMap Linkage Disequilibrium images for DARS2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 610956 disorders: 611105

UniProtKB/Swiss-Prot: SYDM_HUMAN, Q6PI48

Defects in DARS2 are a cause of leukoencephalopathy with brainstem and spinal cord

involvement and lactate elevation (LBSL) [MIM:611105]. LBSL is an autosomal recessive disease and

is defined on the basis of a highly characteristic constellation of abnormalities observed by

magnetic resonance imaging and spectroscopy. Affected individuals develop slowly progressive

cerebellar ataxia, spasticity, and dorsal column dysfunction, sometimes with a mild cognitive

deficit or decline

Human Gene Mutation Database: DARS2
Human Genome Epidemiology Navigator: DARS2 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

9 PubMed articles for DARS2 gene:

Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. (PubMed id 15779907)^{2, 3, 4} Bonnefond L....Sissler M. (2005)
Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation. (PubMed id 17384640)^{3, 4} Scheper G.C.... van der Knaap M.S. (2007)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{3, 4} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study. (PubMed id 19209188)³ Reiling E....Dekker J.M. (2009)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. (PubMed id 9878398)³ Quevillon S....Mirande M. (1999)
Leukoencephalopathy with brain stem and spinal cord involvement and high lactate: a genetically proven case with distinct MRI findings. (PubMed id 18619624)¹ Uluc K....van der Knaap M.S. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 55157	HGNC: 25538	AceView: FLJ10514	Ensembl:ENSG00000117593	euGenes: HUgn55157
ECgene: DARS2	H-InvDB: DARS2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
GeneReviews	http://www.genetests.org/query?gene=DARS2

Licensable Technologies for DARS2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for DARS2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DARS2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DARS2		Antibodies for DARS2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DARS2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (DARS2)
	Antibodies (DARS2)
	Chimera RNAi (DARS2)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (DARS2)
	Antibodies (DARS2)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for DARS2

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for DARS2

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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DARS2 Gene at Home site.
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DARS2 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for DARS2

Summaries
for DARS2

Genomic Location
for DARS2

Proteins
for DARS2

Protein Domains/
Families
for DARS2

Gene Function
for DARS2

Pathways & Interactions
for DARS2

Drugs & Compounds
for DARS2

Transcripts
for DARS2

Expression
for DARS2

Orthologs
for DARS2

Paralogs
for DARS2

SNPs/Variants
for DARS2

Disorders & Mutations
for DARS2

Medical News
for DARS2

Publications
for DARS2

Search for DARS2

Genome Databases showing DARS2

Other Databases showing DARS2

Specialized Databases showing DARS2

Licensable Technologies
for DARS2

Services
for DARS2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DARS2 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor DARS2

Summariesfor DARS2

Genomic Locationfor DARS2

Proteinsfor DARS2

Protein Domains/Familiesfor DARS2

Gene Functionfor DARS2

Pathways & Interactionsfor DARS2

Drugs & Compoundsfor DARS2

Transcriptsfor DARS2

Expression for DARS2

Orthologsfor DARS2

Paralogsfor DARS2

SNPs/Variantsfor DARS2

Disorders & Mutationsfor DARS2

Medical Newsfor DARS2

Publicationsfor DARS2

Search for DARS2

Genome Databases showing DARS2

Other Databases showing DARS2

Specialized Databases showing DARS2

Licensable Technologiesfor DARS2

Servicesfor DARS2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DARS2

Summaries
for DARS2

Genomic Location
for DARS2

Proteins
for DARS2

Protein Domains/
Families
for DARS2

Gene Function
for DARS2

Pathways & Interactions
for DARS2

Drugs & Compounds
for DARS2

Transcripts
for DARS2

Expression
for DARS2

Orthologs
for DARS2

Paralogs
for DARS2

SNPs/Variants
for DARS2

Disorders & Mutations
for DARS2

Medical News
for DARS2

Publications
for DARS2

Licensable Technologies
for DARS2

Services
for DARS2