DARS2 Gene
protein-coding GIFtS: 60
GCID: GC01P173793
|
|
aspartyl-tRNA synthetase 2, mitochondrial
| |
Aliases
for DARS2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Aspartyl-TRNA Synthetase 2, Mitochondrial1 2 | | Aspartate TRNA Ligase 2, Mitochondrial2 | | EC 6.1.1.123 8 | | Aspartate--TRNA Ligase, Mitochondrial2 | | FLJ105141 | | Aspartyl-TRNA Synthetase, Mitochondrial2 | | ASPRS2 | | AspRS3 | | LBSL2 | | Aspartyl-TRNA Synthetase3 | | MT-ASPRS2 | | ASPRS. LBSL5 | | RP3-383J4.22 | | EC 6.1.18 |
Export aliases for DARS2 gene to outside databasesPrevious GC identifers: GC01P170526 GC01P172060 GC01P145019 |
Summaries
for DARS2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for DARS2:
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzymethat specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy withbrainstem and spinal cord involvement and lactate elevation (LBSL). (provided by RefSeq, Nov 2009)
|
Genomic Views
for DARS2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the DARS2 gene promoter:
Max1 AML1a Brachyury MyoD AP-4 RelA NF-kappaB NF-kappaB1 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for DARS2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DARS2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q25.1 Ensembl cytogenetic band: 1q25.1 HGNC cytogenetic band: 1q25.1DARS2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P173793: view genomic region
(about GC identifiers)
Start:
|
173,793,641 bp from pter |
End:
|
173,827,684 bp from pter |
Size:
|
34,044 bases |
Orientation:
|
plus strand |
|
Proteins
for DARS2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SYDM_HUMAN, Q6PI48 (See
protein sequence)Recommended Name: Aspartate--tRNA ligase, mitochondrial precursor Size: 645 amino acids; 73563 Da
Subunit: Homodimer
Subcellular location: Mitochondrion matrix
1 PDB 3D structure from  and Proteopedia  for DARS2:4AH6 (3D)
Explore the universe of human proteins at neXtProt for DARS2: NX_Q6PI48
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6PI48
4/26 DME Specific Peptides for DARS2 (Q6PI48) (see all 26)
DARS2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060592.2
ENSEMBL proteins: ENSP00000355086 ENSP00000239457 Reactome Protein details: Q6PI48
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
DARS2 for ontologies About GeneDecksing
DARS2 Antibody Products:
Assay Products for DARS2: |
Protein
Domains /
Families
for DARS2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
DARS2 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry Q6PI48ProtoNet protein and cluster: Q6PI48 4 Blocks protein families: IPB002312 Aspartyl-tRNA synthetase signature IPB004115 GAD domain IPB004364 tRNA synthetase IPB004365 OB-fold nucleic acid binding domain
UniProtKB/Swiss-Prot: SYDM_HUMAN, Q6PI48Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family |
Function
for DARS2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SYDM_HUMAN, Q6PI48Catalytic activity: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)Enzyme Numbers (IUBMB): EC 6.1.1.121 2 EC 6.1.12
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DARS2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DARS2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: DARS2 (NM_018122) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DARS2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DARS2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DARS2 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
DARS2 for ontologies About GeneDecksing
Animal Models:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Dars2):
DARS2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for DARS2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | tRNA Aminoacylation | | | 2 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for DARS2
1 
Kegg Pathway (Kegg details for DARS2):
DARS2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DARS2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 23)
5/45 Interacting proteins for DARS2 (Q6PI483 ENSP000003550864) via UniProtKB, MINT, STRING, and/or I2D (see all 45)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
DARS2 for ontologies About GeneDecksing
|
Drugs & Compounds
for DARS2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for DARS2
5 HMDB Compounds for DARS2 About this table
1 DrugBank Compound for DARS2 About this table
Search CenterWatch for drugs/clinical trials and news about DARS2 / SYDM
|
Transcripts
for DARS2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for DARS2 gene: NM_018122.4 Unigene Cluster for DARS2: Aspartyl-tRNA synthetase 2, mitochondrial Hs.647707 [show with all ESTs]Unigene Representative Sequence: NM_0181224 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000361951(uc001gjh.2) ENST00000471476 ENST00000460076 ENST00000239457
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DARS2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DARS2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: DARS2 (NM_018122) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for DARS2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DARS2 |
Additional cDNA sequence: AK001376.1 AK022754.1 AK290873.1 AL833633.1 BC045173.2 12 DOTS entries: DT.95272513 DT.313079 DT.95366867 DT.102842494 DT.121423412 DT.121423403 DT.95272512 DT.121423394 DT.121423458 DT.121423482 DT.95272510 DT.99970861 24/165 AceView cDNA sequences (see all 165): AA805701 AA514968 BQ023736 CA453987 CA337391 AU125713 BE408981 AL519850 BC045173 BM770614 AI022773 BQ059324 BQ427584 BG254491 BU194090 BM473527 AL701998 AK022754 AA775023 BP340592 CA426604 AI003180 AI022771 BP369043
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for DARS2 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ | 17a | · | 17b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | |
ECgene alternative splicing isoforms for DARS2
|
Expression
for DARS2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| DARS2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCTCATAC
About this image
See DARS2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DARS2
SOURCE GeneReport for Unigene cluster: Hs.647707
SABiosciences Custom PCR Arrays for DARS2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DARS2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat DARS2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DARS2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DARS2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DARS2 |
Orthologs
for DARS2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for DARS2 gene from 9/37 species (see all 37) About this table
ENSEMBL Gene Tree for DARS2 (if available)
TreeFam Gene Tree for DARS2 (if available) |
Paralogs
for DARS2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for DARS2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for DARS2 (173793641 - 173827684 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for DARS2
1 CNV: 3320
Human Gene Mutation Database (HGMD): DARS2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DARS2 |
|
Disorders
/ Diseases
for DARS2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
DARS2 for disorders About GeneDecksing
OMIM gene information: 610956
OMIM disorders: 611105
UniProtKB/Swiss-Prot: SYDM_HUMAN, Q6PI48
Defects in DARS2 are a cause of leukoencephalopathy with brainstem and spinal cord involvement and lactateelevation (LBSL) [MIM:611105]. LBSL is an autosomal recessive disease and is defined on the basis of a highlycharacteristic constellation of abnormalities observed by magnetic resonance imaging and spectroscopy. Affectedindividuals develop slowly progressive cerebellar ataxia, spasticity, and dorsal column dysfunction, sometimes with amild cognitive deficit or decline
17  diseases for DARS2: About MalaCardsleukoencephalopathy with brain stem and spinal cord involvement and lactate elevation mitochondrial encephalomyopathy axonal neuropathy autosomal recessive disease
alpers syndrome cerebellar ataxia leigh disease encephalomyopathy
diabetes mellitus multiple sclerosis spasticity ataxia
neuropathy pneumonia tuberculosis malaria
mycobacterium tuberculosis
3 diseases from the University of Copenhagen DISEASES database for DARS2:Alpers syndrome Mitochondrial encephalomyopathy Cerebellar ataxia Human Genome Epidemiology (HuGE) Navigator: DARS2 (2 documents)
Export disorders for DARS2 gene to outside databases
|
Publications
for DARS2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for DARS2 gene, integrated from 9 sources (see all 30):
(articles sorted by number of sources associating them with DARS2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. (PubMed id 15779907)1, 2, 3 Bonnefond L....Sissler M. (2005)
- Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation. (PubMed id 17384640)1, 2 Scheper G.C.... van der Knaap M.S. (2007)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- DARS2 mutations in mitochondrial leucoencephalopathy and multiple sclerosis. (PubMed id 19592391)1, 9 Isohanni P....Suomalainen A. (2010)
- The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
- Leukoencephalopathy with brainstem and spinal cord inv olvement caused by a novel mutation in the DARS2 gene. (PubMed id 21792730)1 Tzoulis C....Bindoff L.A. (2012)
- Leukoencephalopathy with brain stem and spinal cord in volvement and lactate elevation is associated with cell-type-dependent splicing of mtAspRS mRNA. (PubMed id 22023289)1 van Berge L....Scheper G.C. (2012)
- A novel homozygous mutation of DARS2 may cause a seve re LBSL variant. (PubMed id 21815884)1 Miyake N....Matsumoto N. (2011)
- Clinically asymptomatic adult patient with extensive LBSL MRI pattern and DARS2 mutations. (PubMed id 20878420)1 Labauge P....Boespflug-Tanguy O. (2011)
|
External Searches for DARS2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing DARS2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing DARS2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing DARS2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for DARS2 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/DARS2 |
|
| | |
About This Section
| Patent Information for DARS2 gene:
Search GeneIP for patents involving DARS2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for DARS2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for DARS2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DARS2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DARS2 | | | OriGene Protein Over-expression Lysate for DARS2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for DARS2 | | OriGene 3'-UTR Clone for DARS2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DARS2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DARS2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for DARS2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DARS2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DARS2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DARS2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DARS2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DARS2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DARS2 |
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| |  |  |  |  | | | | |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DARS2 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DARS2 |
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