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GIFtS

DAPP1 Gene

protein-coding   GIFtS: 56
GCID: GC04P100737

dual adaptor of phosphotyrosine and 3-phosphoinositides
  Search for DAPP1
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 Human Malady Compendium 
Biological research products
for DAPP1    

Aliases
for DAPP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides1 2
BAM321 2 3 5
B Lymphocyte Adapter Protein Bam322 3
B-Cell Adapter Molecule Of 32 KDa2 3
HDAPP11
Dual Adapter For Phosphotyrosine And 3-Phosphotyrosine And 3-Phosphoinositide2

External Ids:    HGNC: 165001   Entrez Gene: 270712   Ensembl: ENSG000000701907   OMIM: 6057685   UniProtKB: Q9UN193   

Export aliases for DAPP1 gene to outside databases

Previous GC identifers: GC04P100985 GC04P101130 GC04P101196 GC04P101095 GC04P096476


Summaries
for DAPP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: DAPP1_HUMAN, Q9UN19
Function: May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of
PI3K

Gene Wiki entry for DAPP1


Genomic Views
for DAPP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DAPP1 gene promoter:
         c-Fos   STAT1   AP-1   ATF-2   STAT1beta   c-Jun   STAT1alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DAPP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for DAPP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DAPP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q25-q27   Ensembl cytogenetic band:  4q23   HGNC cytogenetic band: 4q25-q27

DAPP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DAPP1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P100737:  view genomic region     (about GC identifiers)

Start:
 100,737,981 bp from pter      End:
 100,791,347 bp from pter
Size:
 53,367 bases      Orientation:
 plus strand

Proteins
for DAPP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DAPP1_HUMAN, Q9UN19 (See protein sequence)
Recommended Name: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide  
Size: 280 amino acids; 32194 Da
Subunit: Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation
leading to its translocation
2 PDB 3D structures from and Proteopedia for DAPP1:
1FAO (3D)        1FB8 (3D)    
Secondary accessions: Q8TCK5 Q9UHF2
Alternative splicing: 2 isoforms:  Q9UN19-1   Q9UN19-2   

Explore the universe of human proteins at neXtProt for DAPP1: NX_Q9UN19

Post-translational modifications:

  • Phosphorylated on tyrosine residues1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UN19

    • DAPP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_055210.2  
    ENSEMBL proteins: 
     ENSP00000296414   ENSP00000423602  
    Reactome Protein details: Q9UN19
    Human Recombinant Protein Products: 
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    Novus Biologicals DAPP1 Proteins
    Novus Biologicals DAPP1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for DAPP1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005886plasma membrane TAS--


    DAPP1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for DAPP1

    Protein Domains /
    Families
    for DAPP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    DAPP1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom
     IPR000980 SH2

    Graphical View of Domain Structure for InterPro Entry Q9UN19

    ProtoNet protein and cluster: Q9UN19

    2 Blocks protein families:
    IPB000980 SH2 domain signature
    IPB001849 Pleckstrin-like


    UniProtKB/Swiss-Prot: DAPP1_HUMAN, Q9UN19
    Similarity: Contains 1 PH domain
    Similarity: Contains 1 SH2 domain


    Function
    for DAPP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: DAPP1_HUMAN, Q9UN19
    Function: May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of
    PI3K
    Induction: Upon B-cell activation

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DAPP1
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate DAPP1:
    hsa-miR-548p hsa-miR-653 hsa-miR-520f hsa-miR-4255 hsa-miR-513c hsa-miR-633 hsa-miR-591 hsa-miR-514b-5p
    SwitchGear 3'UTR luciferase reporter plasmid: DAPP1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DAPP1 (see all 7)
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    Gene Editing
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DAPP1 

    Cell Line
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    Search LifeMap BioReagents cell lines for DAPP1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DAPP1

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004725protein tyrosine phosphatase activity NAS--
    GO:0005543phospholipid binding NAS10432293
    GO:0005547phosphatidylinositol-3,4,5-trisphosphate binding IDA11001876
    GO:0043325phosphatidylinositol-3,4-bisphosphate binding IDA17823121


    DAPP1 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Dapp1tm1Mnz for DAPP1
         3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Dapp1):
     cellular  hematopoietic system  immune system 

    DAPP1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for DAPP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1B cell receptor signaling pathway
    		B cell receptor signaling pathway1.00
    		PI3K Signaling in B-Lymphocyte0.35
    		BCR signaling pathway0.41
    2Immune System
    		Immune System1.00
    		Adaptive Immune System0.59
    3Assembly of Signalosomes at the Activated BCR
    		Assembly of Signalosomes at the Activated BCR1.00
    		Antigen Activates B Cell Receptor Leading to Generation of Second Messengers0.78
    4Signaling by the B Cell Receptor (BCR)
    		Signaling by the B Cell Receptor (BCR)1.00
    5B Cell Receptor Signaling Pathway
    		B Cell Receptor Signaling Pathway1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for DAPP1
        PI3K Signaling in B-Lymphocyte

    3 BioSystems Pathways for DAPP1 
        B Cell Receptor Signaling Pathway
    BCR signaling pathway
    Class I PI3K signaling events

    5        Reactome Pathways for DAPP1
        Assembly of Signalosomes at the Activated BCR
    Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
    Adaptive Immune System
    Immune System
    Signaling by the B Cell Receptor (BCR)


    1         Kegg Pathway  (Kegg details for DAPP1):
        B cell receptor signaling pathway


    DAPP1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for DAPP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/40 Interacting proteins for DAPP1 (Q9UN192, 3 ENSP000002964144) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ERBB3P218602, 3, ENSP000002671014MINT-74510 I2D: score=2 STRING: ENSP00000267101
    BTKQ061873, ENSP000003081764I2D: score=1 STRING: ENSP00000308176
    LCKP062393, ENSP000003378254I2D: score=1 STRING: ENSP00000337825
    PLCG1P191743, ENSP000002440074I2D: score=1 STRING: ENSP00000244007
    PLCG2P168853, ENSP000003523364I2D: score=1 STRING: ENSP00000352336
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006470protein dephosphorylation NAS10432293
    GO:0007165signal transduction TAS10432293
    GO:0035335peptidyl-tyrosine dephosphorylation NAS--


    DAPP1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for DAPP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    DAPP1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DAPP1

    1 DrugBank Compound for DAPP1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Inositol 1,3,4,5-Tetrakisphosphate-- --target--17139284 17016423

    1 Novoseek chemical compound relationship for DAPP1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    phosphatidylinositol 55.4 1 10770799 (1)

    Search CenterWatch for drugs/clinical trials and news about DAPP1 

    Transcripts
    for DAPP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for DAPP1 gene: 
    NM_014395.2  

    Unigene Cluster for DAPP1:

    Dual adaptor of phosphotyrosine and 3-phosphoinositides
    Hs.436271  [show with all ESTs]
    Unigene Representative Sequence: NM_014395
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296414(uc003hvf.4 uc010ilh.3) ENST00000512369 ENST00000507994(uc011cek.2)
    ENST00000514301

    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate DAPP1:
    hsa-miR-548p hsa-miR-653 hsa-miR-520f hsa-miR-4255 hsa-miR-513c hsa-miR-633 hsa-miR-591 hsa-miR-514b-5p
    SwitchGear 3'UTR luciferase reporter plasmid: DAPP1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DAPP1 (see all 7)
    OriGene shRNA RFP: DAPP1
    OriGene siRNA: DAPP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DAPP1
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DAPP1
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    Additional cDNA sequence: 

    AF161551.1 AF163254.1 AF178987.1 AF186022.1 AK301355.1 AL713793.1 BC012924.1 

    5 DOTS entries:

    DT.115326  DT.95371754  DT.109581  DT.100713958  DT.99936868 

    24/98 AceView cDNA sequences (see all 98):

    AA761790 AI494139 AA806554 BM922611 BF516578 BX118264 AA934575 AA809680 
    AI376097 BG288385 CA428013 AI206889 BI224992 AA459342 Z41202 AF150266 
    AI285859 AA251556 AI632216 AI128099 AA459123 AA418849 AI499165 CD365738 

    GeneLoc Exon Structure


    Expression
    for DAPP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DAPP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TACCATTTTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    DAPP1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LiverLiver LobuleLiver
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See DAPP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DAPP1

    SOURCE GeneReport for Unigene cluster: Hs.436271

    UniProtKB/Swiss-Prot: DAPP1_HUMAN, Q9UN19
    Tissue specificity: Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and
    skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DAPP1

    Orthologs
    for DAPP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for DAPP1 gene from 4/13 species (see all 13)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Dapp11 , 5 dual adaptor for phosphotyrosine and 3-phosphoinositides more1, 5 87.74(n)1
    93.21(a)1    		   3 (63.98 cM)5
    263771  NM_011932.21  NP_036062.11 
     1379310075 
    chicken
    (Gallus gallus)    		 Aves DAPP11 dual adaptor of phosphotyrosine and 3-phosphoinositides 77.1(n)
    87.73(a)    		   425211  NM_001012933.1  NP_001012951.1 
    lizard
    (Anolis carolinensis)    		 Reptilia DAPP16
    		 --
    		 83(a)
    		 1 ↔ 1
    		 GL343323.1(1063511-1074488)
    zebrafish
    (Danio rerio)    		 Actinopterygii dapp11 dual adaptor of phosphotyrosine and 3-phosphoinositides 66.26(n)
    72.84(a)    		   550386  NM_001017691.1  NP_001017691.1 


    ENSEMBL Gene Tree for DAPP1 (if available)
    TreeFam Gene Tree for DAPP1 (if available) 

    Paralogs
    for DAPP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for DAPP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for DAPP1
         1 CNV: 51209
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DAPP1
    DNA2.0 Custom Variant and Variant Library Synthesis for DAPP1

    Disorders / Diseases
    for DAPP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    DAPP1 for disorders           About MalaCards

    DAPP1 for disorders           About GeneDecksing

    OMIM gene information: 605768    OMIM disorders: --


    Export disorders for DAPP1 gene to outside databases

    Publications
    for DAPP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DAPP1 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with DAPP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides. (PubMed id 10432293)1, 2, 3 Dowler S.... Alessi D.R. (1999)
    2. A novel B lymphocyte-associated adaptor protein, Bam32, regulates antigen receptor signaling downstream of phosphatidylinositol 3- kinase. (PubMed id 10770799)1, 2, 9 Marshall A.J.... Clark E.A. (2000)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    5. Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains. (PubMed id 10983984)1, 2 Ferguson K.M.... Lemmon M.A. (2000)
    6. The adaptor protein Bam32 regulates Rac1 activation and actin remodeling through a phosphorylation-dependent mechanism. (PubMed id 15247305)1, 9 Allam A....Marshall A.J. (2004)
    7. Mechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domains. (PubMed id 17823121)1, 9 Manna D....Cho W. (2007)
    8. The adaptor protein Bam32 in human dendritic cells pa rticipates in the regulation of MHC class I-induced CD8+ T cell activation. (PubMed id 21930970)1 Ortner D....Heufler C. (2011)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)7 Imming P....Meyer A. (2006)

    External Searches for DAPP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing DAPP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27071 HGNC: 16500 AceView: DAPP1 Ensembl:ENSG00000070190 euGenes: HUgn27071
    ECgene: DAPP1 Kegg: 27071 H-InvDB: DAPP1

    Other Databases showing DAPP1 gene

    (According to HUGE)
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    Specialized Databases showing DAPP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DAPP1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for DAPP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for DAPP1 gene:
    Search GeneIP for patents involving DAPP1

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