Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

DAPL1 Gene

protein-coding GIFtS: 41
GCID: GC02P159651

death associated protein-like 1

Search for DAPL1
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Death Associated Protein-Like 1¹ ²
Early Epithelial Differentiation-Associated Protein² ³
Death-Associated Protein-Like 1²
EEDA³

External Ids:	HGNC: 21490¹	Entrez Gene: 92196²	Ensembl: ENSG00000163331⁷	UniProtKB: A0PJW8³

Export aliases for DAPL1 gene to outside databases

Previous GC identifers: GC00U911651 GC02U900711 GC02P159361 GC02P151540

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: DAPL1_HUMAN, A0PJW8

Function: May play a role in the early stages of epithelial differentiation or in apoptosis (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_005403.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the DAPL1 gene promoter:
GR p53 GR-beta POU3F1 MIF-1 Evi-1 COMP1 FOXO1a GR-alpha FOXO1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DAPL1 promoter sequence

Search SABiosciences Chromatin IP Primers for DAPL1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DAPL1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q24.1 Ensembl cytogenetic band: 2q24.1 HGNC cytogenetic band: 2q24

DAPL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DAPL1 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P159651: view genomic region (about GC identifiers)

Start:	159,651,829 bp from pter	End:	159,719,293 bp from pter
Size:	67,465 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DAPL1_HUMAN, A0PJW8 (See protein sequence)

Recommended Name: Death-associated protein-like 1

Size: 107 amino acids; 11880 Da

Secondary accessions: A0PJW9 B9EIK6

Explore the universe of human proteins at neXtProt for DAPL1: NX_A0PJW8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_A0PJW8

DAPL1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001017920.2

ENSEMBL proteins:

ENSP00000309538 ENSP00000386422 ENSP00000385306

Human Recombinant Protein Products for DAPL1:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: DAPL1 OriGene Custom Protein Services for DAPL1
	GenScript Custom Purified and Recombinant Proteins Services for DAPL1
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for DAPL1

DAPL1 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for DAPL1
	GenScript Custom Superior Antibodies Services for DAPL1
	Novus Biologicals DAPL1 Antibody
	Abcam antibodies for DAPL1
	Uscn Antibodies for DAPL1
	Search ThermoFisher Antibodies for DAPL1

Assay Products for DAPL1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for DAPL1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for DAPL1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

DAPL1 for domains About GeneDecksing

1 InterPro domain/family:

IPR024130 DAP1/DAPL1

Graphical View of Domain Structure for InterPro Entry A0PJW8

ProtoNet protein and cluster: A0PJW8

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: DAPL1_HUMAN, A0PJW8

Function: May play a role in the early stages of epithelial differentiation or in apoptosis (By similarity)

Phenotypes:
3 GenomeRNAi human phenotypes for DAPL1:

Increased S DNA content

Increased cell size

S arrest

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DAPL1

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DAPL1
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DAPL1
		SwitchGear 3'UTR luciferase reporter plasmid: DAPL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DAPL1 (see all 7) OriGene shRNA RFP: DAPL1 OriGene siRNA: DAPL1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DAPL1
		Sirion Biotech Custom design and validation of potent shRNA sequences against DAPL1

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for DAPL1
			Sirion Biotech Customized adenovirus for overexpression of DAPL1 Sirion Biotech Customized adenovirus for potent knockdown of DAPL1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DAPL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DAPL1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: DAPL1 (NM_001017920)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DAPL1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DAPL1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for DAPL1
		Search LifeMap BioReagents cell lines for DAPL1
		Sirion Biotech Customized stable knockdown cell line services for DAPL1 Sirion Biotech Customized inducible knockdown cell line services for DAPL1 Sirion Biotech Customized stable overexpressing cell line services for DAPL1 Sirion Biotech Customized inducible overexpressing cell line services for DAPL1

In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for DAPL1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for DAPL1

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006915	apoptotic process	IEA	--
GO:0030154	cell differentiation	IEA	--

DAPL1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for DAPL1
Search CenterWatch for drugs/clinical trials and news about DAPL1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for DAPL1 gene:

NM_001017920.2

Unigene Cluster for DAPL1:

Death associated protein-like 1

Hs.59761 [show with all ESTs]

Unigene Representative Sequence: EL950760

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000309950(uc002uaf.3) ENST00000409042 ENST00000343761

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DAPL1
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate DAPL1
		SwitchGear 3'UTR luciferase reporter plasmid: DAPL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DAPL1 (see all 7) OriGene shRNA RFP: DAPL1 OriGene siRNA: DAPL1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DAPL1
		Sirion Biotech Custom design and validation of potent shRNA sequences against DAPL1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DAPL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DAPL1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: DAPL1 (NM_001017920)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for DAPL1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DAPL1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DAPL1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat DAPL1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DAPL1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DAPL1

Additional cDNA sequence:

AF086541.1 AY324399.1 BC127682.1 BC127683.1 BC140719.1

1 DOTS entry:

DT.212081

24/37 AceView cDNA sequences (see all 37):

C00396 AA365801 AA365503 CD675155 AA453863 AW131631 AI632902 AI692575

CK299997 AA442475 AF086541 BX117859 AA732993 AA365504 BG818506 AA975337

BM129664 BQ185417 AA453779 BQ189090 W96131 BQ186911 BM128924 AA988869

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

DAPL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCGCATCAAA

About this image

DAPL1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Pancreas

Islets of Langerhans

Mature Beta Cells

Pancreas

Adipose

Body Subcutaneous White Adipose

Adipose

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ progenitor E68 (Embryonic Progenitor Cell)

See DAPL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for DAPL1

SOURCE GeneReport for Unigene cluster: Hs.59761

UniProtKB/Swiss-Prot: DAPL1_HUMAN, A0PJW8

Tissue specificity: Expressed in hair follicle (at protein level)

SABiosciences Custom PCR Arrays for DAPL1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DAPL1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat DAPL1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DAPL1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DAPL1

In Situ
Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for DAPL1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for DAPL1 gene from 4/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Dapl1^{1 , 5}	death associated protein-like 1^{1, 5}	82.87(n)¹ 81.31(a)¹		2 (33.81 cM)⁵ 76747¹ NM_029723.3¹ NP_083999.1¹ 59484653⁵
chicken (Gallus gallus)	Aves	DAPL1⁶	Uncharacterized protein	40(a)	1 ↔ 1	7(38079508-38093859)
African clawed frog (Xenopus laevis)	Amphibia	CB559023.1²	--	79.95(n)		CB559023.1
zebrafish (Danio rerio)	Actinopterygii	dap1b⁶ dap1b⁶	death associated protein 1b	39(a) 39(a)	many → 1 many → 1	9(54130194-54133678) 9(53975568-53979084)

ENSEMBL Gene Tree for DAPL1 (if available)
TreeFam Gene Tree for DAPL1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for DAPL1 gene

12 SIMAP similar genes for DAPL1 using alignment to 3 protein entries: DAPL1_HUMAN (see all proteins):

OR7E5P OR1D5 LOC441453 OR1F12 OR2J4P OR7E85P

FKSG35 OR2A1 OR7A17 OR8I2 OR10C1 DAP

DAPL1 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for DAPL1
PGOHUM00000234488

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs148327470^1,2		--	159649935(+)	`AGAAGA/GTTTAA`	1	--	us2k¹		0	--	--	--	--
rs182329184^1,2		--	159649965(+)	`CCACCC/TACAGA`	1	--	us2k¹		0	--	--	--	--
rs186226199^1,2		--	159649973(+)	`AGAATA/GCCACT`	1	--	us2k¹		0	--	--	--	--
rs190634534^1,2		--	159650224(+)	`TTTCTA/GTTCCT`	1	--	us2k¹		0	--	--	--	--
rs182811898^1,2		--	159650283(+)	`GTAGCA/TTTTTT`	1	--	us2k¹		0	--	--	--	--
rs10933505^1,2	C,F,A,H	--	159650308(+)	`CCATTA/TAACGT`	1	--	us2k¹		27		NS EA NA CSA WA	2768
rs4561615^1,2	C,F,H	--	159650386(+)	`CACAAT/CCTGTT`	1	--	us2k¹		19		NS EA NA WA CSA	2033
rs74498770^1,2	F	--	159650400(+)	`CCATTC/ATACAG`	1	--	us2k¹		1		WA	118
rs185569596^1,2		--	159650427(+)	`TTTCTA/CACTTT`	1	--	us2k¹		0	--	--	--	--
rs141503903^1,2		--	159650486(+)	`GTGTAC/TATATG`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for DAPL1 (159651829 - 159719293 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for DAPL1
1 CNV: 53156
4 Indels: 12102 90094 63221 90095

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DAPL1

DNA2.0 Custom Variant and Variant Library Synthesis for DAPL1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

DAPL1 for disorders About MalaCards

DAPL1 for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: DAPL1 (1 document)

Export disorders for DAPL1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for DAPL1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with DAPL1)

Utopia: connect your pdf to the dynamic
world of online information

Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)¹ Flachsbart F....Nebel A. (2010)
EEDA: a protein associated with an early stage of stratified epithelial differentiation. (PubMed id 15920738)² Sun L.... Lavker R.M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Expressed sequence tag analysis of adult human lens for the NEIBank project: over 2000 non-redundant transcripts, novel genes and splice variants. (PubMed id 12107413)¹ Wistow G.... Peterson K. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 92196	HGNC: 21490	AceView: OR7E28P	Ensembl:ENSG00000163331	euGenes: HUgn92196
ECgene: DAPL1	H-InvDB: DAPL1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for DAPL1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for DAPL1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for DAPL1 gene:
Search GeneIP for patents involving DAPL1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for DAPL1
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DAPL1		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for DAPL1
	OriGene Protein Over-expression Lysate for DAPL1		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for DAPL1		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DAPL1		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DAPL1
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for DAPL1		OriGene Custom Protein Services for DAPL1
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DAPL1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DAPL1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DAPL1
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DAPL1
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DAPL1
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DAPL1

	GenScript Custom Purified and Recombinant Proteins Services for DAPL1		GenScript cDNA clones with any tag delivered in your preferred vector for DAPL1
	GenScript Custom Assay Services for DAPL1		GenScript Custom Superior Antibodies Services for DAPL1
	GenScript Custom overexpressing Cell Line Services for DAPL1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in DAPL1 promoter
	Search Chromatin IP Primers for DAPL1
	RT² qPCR Primer Assay in human, mouse, rat DAPL1
	Search GNC Networks for DAPL1
	SABiosciences Custom PCR Arrays for DAPL1

Search Tocris compounds for DAPL1

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	DAPL1 antibodies

	Antibodies for DAPL1
	See all of Abcam's Antibodies, Kits and Proteins for DAPL1
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

DAPL1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for DAPL1

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for DAPL1

	SwitchGear 3'UTR luciferase reporter plasmids for DAPL1
	SwitchGear Promoter luciferase reporter plasmids for DAPL1

Search ThermoFisher Antibodies for DAPL1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DAPL1

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for DAPL1

Sirion Biotech Customized:

	stable knockdown cell line services for DAPL1
	inducible knockdown cell line services for DAPL1
	design and validation of potent shRNA sequences against DAPL1
	adenovirus for potent knockdown of DAPL1
	adenovirus for overexpression of DAPL1
	stable overexpressing cell line services for DAPL1
	inducible overexpressing cell line services for DAPL1

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes DAPL1 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

DAPL1 Gene

death associated protein-like 1

Aliases
for DAPL1 gene

Summaries
for DAPL1 gene

Genomic Views
for DAPL1 gene

Proteins
for DAPL1 gene

Protein Domains /
Families
for DAPL1 gene

Function
for DAPL1 gene

Pathways & Interactions
for DAPL1 gene

Drugs & Compounds
for DAPL1 gene

Transcripts
for DAPL1 gene

Expression
for DAPL1 gene

Orthologs
for DAPL1 gene

Paralogs
for DAPL1 gene

Genomic Variants
for DAPL1 gene

Disorders / Diseases
for DAPL1 gene

Publications
for DAPL1 gene

External Searches for DAPL1 gene

Genome Databases showing DAPL1 gene

Other Databases showing DAPL1 gene

Specialized Databases showing DAPL1 gene

Intellectual Property
for DAPL1 gene

Products
for DAPL1 gene

View Random Gene

Advanced Search

Export list of displayed genes

DAPL1 Gene

death associated protein-like 1

Aliasesfor DAPL1 gene

Summariesfor DAPL1 gene

Genomic Viewsfor DAPL1 gene

Proteinsfor DAPL1 gene

Protein Domains /Familiesfor DAPL1 gene

Functionfor DAPL1 gene

Pathways & Interactionsfor DAPL1 gene

Drugs & Compoundsfor DAPL1 gene

Transcriptsfor DAPL1 gene

Expression for DAPL1 gene

Orthologsfor DAPL1 gene

Paralogsfor DAPL1 gene

Genomic Variantsfor DAPL1 gene

Disorders / Diseasesfor DAPL1 gene

Publicationsfor DAPL1 gene

External Searches for DAPL1 gene

Genome Databases showing DAPL1 gene

Other Databases showing DAPL1 gene

Specialized Databases showing DAPL1 gene

Intellectual Propertyfor DAPL1 gene

Productsfor DAPL1 gene

View Random Gene

Aliases
for DAPL1 gene

Summaries
for DAPL1 gene

Genomic Views
for DAPL1 gene

Proteins
for DAPL1 gene

Protein Domains /
Families
for DAPL1 gene

Function
for DAPL1 gene

Pathways & Interactions
for DAPL1 gene

Drugs & Compounds
for DAPL1 gene

Transcripts
for DAPL1 gene

Expression
for DAPL1 gene

Orthologs
for DAPL1 gene

Paralogs
for DAPL1 gene

Genomic Variants
for DAPL1 gene

Disorders / Diseases
for DAPL1 gene

Publications
for DAPL1 gene

Intellectual Property
for DAPL1 gene

Products
for DAPL1 gene