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DAPK2 Gene

protein-coding GIFtS: 54

GC15M061986

death-associated protein kinase 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DRP-1 ^¹, ², ³
DRP1 ^²
EC 2.7.11.1 ^³
MGC119312 ^¹, ²

Descriptions
DAP kinase 2 ^², ³
DAP-kinase-related protein 1 ^², ³
death-associated kinase 2 ^²
death-associated protein kinase 2 ^²

External Ids
HGNC: 2675¹
Entrez Gene: 23604²
UniProtKB: Q9UIK4³
Ensembl: ENSG00000035664⁷

Search outside databases for aliases for DAPK2 gene

Previous GC identifers: GC15M059986 GC15M057358 GC15M061778 GC15M061915

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for DAPK2:

This gene encodes a protein that belongs to the serine/threonine protein kinase family. This

protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding

domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a

positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell

apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq]

UniProtKB/Swiss-Prot: DAPK2_HUMAN, Q9UIK4

Function: Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator

of apoptosis

Gene Wiki entry for DAPK2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DAPK2 gene

Entrez Gene cytogenetic band: 15q22.31 Ensembl cytogenetic band: 15q22.31 HGNC cytogenetic band: 15q22.1

DAPK2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 15 GeneLoc Exon Structure

GeneLoc location for GC15M061986: (about GC identifiers)

Start:	61,986,288 bp from pter
End:	62,125,574 bp from pter
Size:	139,287 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000015.8 NT_010194.16

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: DAPK2_HUMAN, Q9UIK4 (See protein sequence)

Recommended Name: Death-associated protein kinase 2

Size: 370 amino acids; 42898 Da

Cofactor: Magnesium

Subunit: Homodimer. Homodimerization is required for apoptotic function and is inhibited by

autophosphorylation at Ser-318

Subcellular location: Cytoplasm

PDB structures from and Proteopedia :

1WMK (3D)

1WRZ (3D)

1Z9X (3D)

1ZWS (3D)

2A27 (3D)

2A2A (3D)

2CKE (3D)

Secondary accessions: O75892 Q24JS1

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_055141.2

ENSEMBL proteins:

ENSP00000379136 ENSP00000261891

Human Recombinant Proteins

	Invitrogen human recombinant proteins for DAPK2
	Millipore Purified and/or Recombinant DAPK2 Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (DAP Kinase 2)
	Human Recombinant Proteins from Abnova (DAPK2)

OriGene Purified Recombinant Human Protein: DAPK2

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IDA	10376525

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Antibodies for DAPK2:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of DAPK2
	Sigma-Aldrich Antibody Arrays and Antibodies for DAPK2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (DAP Kinase 2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (DAPK2)
	Novus Biologicals Antibodies for DAPK2

Assays for DAPK2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9UIK4

ProtoNet protein and cluster: Q9UIK4

UniProtKB/Swiss-Prot: DAPK2_HUMAN, Q9UIK4

Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP

kinase subfamily

Similarity: Contains 1 protein kinase domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAPK2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DAPK2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014326

Applied Biosystems Silencer® siRNAs for DAPK2

Sigma-Aldrich siRNA and siRNA Panels for DAPK2

Sigma-Aldrich shRNA Panels and shRNA for DAPK2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_014326
Myc/DDK tagged cDNA clone in CMV expression vector: NM_014326
untagged cDNA clone in CMV expression vector: NM_014326

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_014326

UniProtKB/Swiss-Prot: DAPK2_HUMAN, Q9UIK4

Function: Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator

of apoptosis

Catalytic activity: ATP + a protein = ADP + a phosphoprotein

Enzyme regulation: Negatively regulated by autophosphorylation on Ser-318

Enzyme Number (IUBMB): EC 2.7.11.1

1 MGI phenotypic allele for Dapk2 (no phenotypes)

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0004683	calmodulin-dependent protein kinase activity	TAS	10629061
GO:0005516	calmodulin binding	IDA	10376525
GO:0005524	ATP binding	IDA	10376525
GO:0016740	transferase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

3 Interacting proteins for DAPK2 (ENSP00000261891³ Q9UIK4¹) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DAPK2	Q9UIK4¹	EBI-77154, EBI-77154
DAPK3	ENSP00000301264³	STRING (score=.808)
--	ENSP00000365095³	STRING (score=.805)

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4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006468	protein amino acid phosphorylation	IDA	10376525
GO:0006915	apoptosis	IEA	--
GO:0006917	induction of apoptosis	IMP	10376525
GO:0007243	protein kinase cascade	IDA	10376525

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for DAPK2
1 Novoseek chemical compound relationship for DAPK2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
threonine	63.47	2	11230133 (1), 17139808 (1)

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(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAPK2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DAPK2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014326

Sigma-Aldrich siRNA and siRNA Panels for DAPK2

Sigma-Aldrich shRNA Panels and shRNA for DAPK2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_014326

REFSEQ mRNAs for DAPK2 gene:

NM_014326.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_014326

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_014326
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_014326
                                 untagged cDNA clone in CMV expression vector: NM_014326

Additional cDNA sequence:

AB018001.1 AF052941.1 AK026801.1 AK094290.1 AK310967.1 BC114506.1 BC114951.1

4 DOTS entries:

DT.304225 DT.75141877 DT.91684430 DT.95161584

24/31 AceView cDNA sequences (see all 31 ):

NM_014326 BP345940 CB153964 AA327032 AB018001 AI362933 AA989377 AW058406

AK026801 AI138960 AA858002 AI499351 BX644667 AA594637 AI764982 BU687995

AW004707 AF052941 BE883503 AU100378 BI464915 AA952879 AW022329 H27328

highest scoring ESTs for DAPK2:

AF052941 AA858002 AA952879 AB018001 AI499351 AU076475 AA327032 AA594637 AA937590 AA989377

Unigene Cluster for DAPK2:

Death-associated protein kinase 2

Hs.237886 [show with all ESTs]

Unigene Representative Sequence: BC114951

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000395790 ENST00000261891

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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DAPK2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DAPK2

¹ / ² / ³

6 probe-sets matching DAPK2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34912_at²^{, 3}	U95-A	1	1.00	1.00	0.75	0.97	AF052941	1.00	1.00	1.00	1
86878_at²^{, 3}	U95-E	1	1.00	1.00	0.91	1.04	AI499351	0.80	1.00	0.91	1
206324_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_014326	0.60	1.00	0.82	1
215184_at²^{, 3}	U133-A	2	1.00	0.95	--	--	AK026801	0.60	1.00	0.82	1
206324_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
215184_at²	U133Plus2	2	1.00	0.95	--	--	--	--	--	--	--

GeneDecks DAPK2 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.237886
UniProtKB/Swiss-Prot: DAPK2_HUMAN, Q9UIK4
Tissue specificity: Ubiquitously expressed in all tissue types examined. High levels in heart, lung
and skeletal muscle

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DAPK2 gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DAPK2¹	--	death-associated protein kinase 2	93.51(n) 96.76(a)	610682 XM_848224.1 XP_853317.1
chimpanzee (Pan troglodytes)	DAPK2¹	--	death-associated protein kinase 2	99.64(n) 100(a)	747631 XM_001157721.1 XP_001157721.1
cow (Bos taurus)	DAPK2¹	--	death-associated protein kinase 2	93.12(n) 94.99(a)	529131 XM_607571.3 XP_607571.3
mouse (Mus musculus)	Dapk2^{1, 5}	9 (32.00 cM)⁵	death-associated protein kinase 2^{1, 5}	92.07(n)¹ 97.3(a)¹	13143¹ NM_010019.2¹ NP_034149.2¹ AB018002⁵ AB058015⁵ (see all 11)
zebrafish (Danio rerio)	im:7162965¹	--	im:7162965	74.44(n) 79.86(a)	556756 XM_679634.3 XP_684726.3

About this table Species with no ortholog for DAPK2

ENSEMBL Gene Tree for DAPK2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for DAPK2 gene

DAPK3² DAPK1² MYLK²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1010 NCBI SNPs in DAPK2 are shown (see all 1010 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 311)

AB	SNP ID	Valid	Chr 15 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs332271^1,2	A,C,F,H,O	62126801(-)	`TCCCAA/GTGTCC`	1	--	ng3¹		13	MN EU EA WA	1438
	rs1550659^1,2	A,C,F,H,O	61986126(-)	`CCCCTC/TCGGTG`	1	--	ng5¹		13	MN EU EA WA NA	1204
	rs6494452^1,2	A,C,F,H	61986261(+)	`gggccG/Accata`	1	--	ng5¹		4	EU EA WA	392
	rs332270^1,2	A,C,F,H	62126853(-)	`TCCTGG/CACCCG`	1	--	ng3¹		7	MN EU EA WA NA	782
	rs11629676^1,2	A,C,F,H	62126992(+)	`GTCAAT/CGGACC`	1	--	ng3¹		12	EU EA WA	1258
	rs2241934^1,2	C,F,H	61987410(-)	`CTGAGG/TGGGTT`	1	--	ut3¹ ese³		8	EA NA EU WA	2040
	rs11854049^1,2	C,F,H	61987735(+)	`CTGGGC/ACCAGA`	1	--	ut3¹ ese³		4	EU EA WA	418
	rs12904338^1,2	F	62126045(+)	`TGACAC/TGGTCT`	1	--	ng3¹		2	MN EA	356
--	rs34270163^1,2	C	62005194(+)	`TTACCG/AGGTCT`	1	W/R	mis¹		4	EU EA WA	420
	rs922182^1,2	A,C,F,H,O	62064695(-)	`AGCTCG/AGTCAA`	1	--	int¹		17	EA NA EU WA	1322

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HapMap Linkage Disequilibrium images for DAPK2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

2 Novoseek disease relationships for DAPK2 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
necrosis	10.11	2	11230133 (1), 11980920 (1)
tumors	0.00	1	11980920 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/20 PubMed articles for DAPK2 gene (see all 20 ):

Death-associated protein kinase 2 is a new calcium/calmodulin- dependent protein kinase that signals apoptosis through its catalytic activity. (PubMed id 10376525)^{2, 3, 4} Kawai T.... Akira S. (1999)
Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis. (PubMed id 10629061)^{1, 3, 4} Inbal B.... Kimchi A. (2000)
Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding. (PubMed id 11230133)^{1, 3, 4} Shani G.... Kimchi A. (2001)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. (PubMed id 11980920)^{1, 3} Inbal B....Kimchi A. (2002)
Down-regulation of death-associated protein kinase-2 is required for beta-catenin-induced anoikis resistance of malignant epithelial cells. (PubMed id 18957423)³ Li H....Rosen K.V. (2009)
DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function. (PubMed id 18521079)³ Britschgi A....Tschan M.P. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)
Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)⁴ Greenman C.... Stratton M.R. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 23604	HGNC: 2675	AceView: DAPK2	Ensembl:ENSG00000035664	euGenes: HUgn23604
ECgene: DAPK2	H-InvDB: DAPK2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for DAPK2	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for DAPK2
(Available from WIS Yeda, Salk, Tufts)

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Licensable Technologies for DAPK2 gene:

Weizmann Institute:

DAP Kinase Gene Family: A Novel Target for Treatment of Neurodegenerative Disorders and Cancer

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for DAPK2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DAPK2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DAPK2		Antibodies for DAPK2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DAPK2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (DAPK2)
	Antibodies (DAPK2)
	Chimera RNAi (DAPK2)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (DAP Kinase 2)
	Antibodies (DAP Kinase 2)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for DAPK2

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for DAPK2

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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DAPK2 Gene at Home site.
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DAPK2 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for DAPK2

Summaries
for DAPK2

Genomic Location
for DAPK2

Proteins
for DAPK2

Protein Domains/
Families
for DAPK2

Gene Function
for DAPK2

Pathways & Interactions
for DAPK2

Drugs & Compounds
for DAPK2

Transcripts
for DAPK2

Expression
for DAPK2

Orthologs
for DAPK2

Paralogs
for DAPK2

SNPs/Variants
for DAPK2

Disorders & Mutations
for DAPK2

Medical News
for DAPK2

Publications
for DAPK2

Search for DAPK2

Genome Databases showing DAPK2

Other Databases showing DAPK2

Specialized Databases showing DAPK2

Licensable Technologies
for DAPK2

Services
for DAPK2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DAPK2 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor DAPK2

Summariesfor DAPK2

Genomic Locationfor DAPK2

Proteinsfor DAPK2

Protein Domains/Familiesfor DAPK2

Gene Functionfor DAPK2

Pathways & Interactionsfor DAPK2

Drugs & Compoundsfor DAPK2

Transcriptsfor DAPK2

Expression for DAPK2

Orthologsfor DAPK2

Paralogsfor DAPK2

SNPs/Variantsfor DAPK2

Disorders & Mutationsfor DAPK2

Medical Newsfor DAPK2

Publicationsfor DAPK2

Search for DAPK2

Genome Databases showing DAPK2

Other Databases showing DAPK2

Specialized Databases showing DAPK2

Licensable Technologiesfor DAPK2

Servicesfor DAPK2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DAPK2

Summaries
for DAPK2

Genomic Location
for DAPK2

Proteins
for DAPK2

Protein Domains/
Families
for DAPK2

Gene Function
for DAPK2

Pathways & Interactions
for DAPK2

Drugs & Compounds
for DAPK2

Transcripts
for DAPK2

Expression
for DAPK2

Orthologs
for DAPK2

Paralogs
for DAPK2

SNPs/Variants
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