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DAP3 Gene

protein-coding GIFtS: 66

GC01P153925

death associated protein 3
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DAP-3 ^¹, ², ³
DKFZp686G12159 ^¹, ²
MGC126058 ^¹, ²
MGC126059 ^¹, ²
MRP-S29 ^¹, ², ³
MRPS29 ^¹, ², ³
OTTHUMP00000033480 ^²
OTTHUMP00000033481 ^²
S29mt ^³
bMRP-10 ^¹, ²

Descriptions
Death-associated protein 3 ^², ³
Ionizing radiation resistance conferring protein ^³
death associated protein 3 ^²
mitochondrial 28S ribosomal protein S29 ^²

External Ids
HGNC: 2673¹
Entrez Gene: 7818²
UniProtKB: P51398³
Ensembl: ENSG00000132676⁷

Search outside databases for aliases for DAP3 gene

Previous GC identifers: GC01P153522 GC01P151406 GC01P152436 GC01P152875 GC01P152471

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for DAP3:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein

synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S

subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared

to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian

mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different

species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in

biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a

28S subunit protein that also participates in apoptotic pathways which are initiated by tumor

necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP

and might be a functional partner of the mitoribosomal protein S27. Splice variants that differ in

the 5' UTR have been found for this gene; both variants encode the same protein. Pseudogenes

corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq]

UniProtKB/Swiss-Prot: RT29_HUMAN, P51398

Function: Involved in mediating interferon-gamma-induced cell death

Gene Wiki entry for DAP3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DAP3 gene

Entrez Gene cytogenetic band: 1q21-q22 Ensembl cytogenetic band: 1q22 HGNC cytogenetic band: 1q22

DAP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P153925: (about GC identifiers)

Start:	153,925,473 bp from pter
End:	153,975,425 bp from pter
Size:	49,953 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000001.9 NT_004487.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: RT29_HUMAN, P51398 (See protein sequence)

Recommended Name: 28S ribosomal protein S29, mitochondrial

Size: 398 amino acids; 45566 Da

Subunit: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and

about 30 distinct proteins

Subcellular location: Mitochondrion

Sequence caution: Sequence=AAA57443.1; Type=Frameshift; Positions=349;

Secondary accessions: Q13044 Q96Q20

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_004623.1 NP_387506.1

ENSEMBL proteins:

ENSP00000341692 ENSP00000357320

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (DAP3)
	Human Recombinant Proteins from Abnova (DAP3)

OriGene Purified Recombinant Human Protein: DAP3

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	IEA	--
GO:0005761	mitochondrial ribosome	IEA	--
GO:0005840	ribosome	IEA	--
GO:0015935	small ribosomal subunit	IEA	--

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Antibodies for DAP3:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for DAP3
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (DAP3), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (DAP3)
	Novus Biologicals Antibodies for DAP3

Assays for DAP3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P51398

ProtoNet protein and cluster: P51398

1 Blocks protein family: IPB008092 Death associated protein 3 family signature

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAP3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DAP3)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_033657

Applied Biosystems Silencer® siRNAs for DAP3

Sigma-Aldrich siRNA for DAP3

Sigma-Aldrich shRNA Panels and shRNA for DAP3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_004632
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_004632
untagged cDNA clones in CMV expression vector (see all 2): NM_004632

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004632

UniProtKB/Swiss-Prot: RT29_HUMAN, P51398

Function: Involved in mediating interferon-gamma-induced cell death

Genatlas biochemistry entry for DAP3:

death associated protein 3,ubiquitously expressed,involved in mediating interferon gamma induced

apoptosis,and as well as TNF and TNFRSF6 induced cell death,acting upstream caspases

5 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Dap3):

lethality-prenatal/perinatal

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	17353931

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for DAP3

5/8 Interacting proteins for DAP3 (P51398^{1, 2} ENSP00000341692³) via UniProtKB, MINT, and/or STRING (see all 8 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CNBP	P62633¹	EBI-355912, EBI-1047529
IKBKG	Q9Y6K9²	MINT-48164
NFKB2	Q00653²	MINT-48720
FADD	ENSP00000301838³	STRING (score=.993)
NR3C1	ENSP00000231509³	STRING (score=.981)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006915	apoptosis	IEA	--
GO:0008624	induction of apoptosis by extracellular signals	TAS	7499268
GO:0008637	apoptotic mitochondrial changes	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for DAP3
1 Novoseek chemical compound relationship for DAP3 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
gtp	27.16	1	15908146 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAP3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DAP3)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_033657

Sigma-Aldrich siRNA for DAP3

Sigma-Aldrich shRNA Panels and shRNA for DAP3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004632 NM_033657

REFSEQ mRNAs for DAP3 gene (2 alternative transcripts):

NM_004632.2 NM_033657.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004632 NM_033657

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_004632
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_004632
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_004632

Additional cDNA sequence:

AK225869.1 AK293117.1 AK298201.1 AK302281.1 BC107487.1 BC107488.1 BT019494.1 CR590516.1

CR591643.1 CR592625.1 CR594396.1 CR594545.1 CR595833.1 CR607923.1 CR610352.1 CR612221.1

CR614148.1 CR615460.1 CR617063.1 CR617451.1 CR619968.1 CR620113.1 CR622457.1 CR624311.1

CR624714.1 CR749790.1 U18321.1 X83544.1

24/50 DOTS entries (see all 50 ):

DT.91762257 DT.87042637 DT.121381390 DT.40273529 DT.91762240 DT.100768038 DT.100681162 DT.100857371

DT.100681150 DT.86996667 DT.92069518 DT.100681160 DT.121381453 DT.121381419 DT.121381397 DT.40263059

DT.121381470 DT.92416344 DT.100643439 DT.121381441 DT.121381443 DT.87042635 DT.121381435 DT.121381345

24/643 AceView cDNA sequences (see all 643 ):

BU630590 BG576785 X83544 BX090311 CR592625 AI360964 BM460347 CR594396

AI702515 CF128802 CA445490 AI859934 CR610352 CA310637 BQ722134 CD513622

AA931558 CR594545 CA306852 BQ028486 AI954244 CR607923 AW675270 AI025888

highest scoring ESTs for DAP3:

U18321 AA031716 AA114167 AA129179 AA143772 AA155805 AA181819 AA206302 AA224565 AA256533

Unigene Cluster for DAP3:

Death associated protein 3

Hs.516746 [show with all ESTs]

Unigene Representative Sequence: CR615460

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for DAP3

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13
SP1:			-
SP2:

About this scheme

ECgene alternative splicing isoforms for DAP3

2 Ensembl transcripts including schematic representations:

ENST00000343043 ENST00000368336

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

DAP3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DAP3

¹ / ² / ³

7 probe-sets matching DAP3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
40413_at²^{, 3}	U95-A	1	1.00	1.00	-0.01	0.86	U18321	1.00	1.00	1.00	1
1356_at²^{, 3}	U95-A	1	1.00	1.00	0.84	1.62	U18321	1.00	1.00	1.00	1
52048_at²^{, 3}	U95-C	1	0.31	1.00	0.80	0.56	AI217911	0.60	1.00	0.82	1
208822_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	U18321	1.00	1.00	1.00	1
232516_x_at*²	U133-B	8	1.00	0.43	--	--	--	--	--	--	--
208822_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
232516_x_at*²	U133Plus2	8	1.00	0.43	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGAGGAAGAC

SOURCE GeneReport for Unigene cluster: Hs.516746
Expression variation in blood from EXPOLDB for DAP3
UniProtKB/Swiss-Prot: RT29_HUMAN, P51398
Tissue specificity: Ubiquitous

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DAP3 gene from 5/13 species (see all 13 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DAP3¹	--	death associated protein 3	85.5(n) 84.22(a)	480127 XM_537250.2 XP_537250.1
chimpanzee (Pan troglodytes)	DAP3¹	--	death associated protein 3	97.75(n) 98.02(a)	740852 XM_001143071.1 XP_001143071.1
cow (Bos taurus)	DAP3¹	--	death associated protein 3	89.87(n) 87.69(a)	504320 XM_580421.3 XP_580421.3
rat (Rattus norvegicus)	Dap3¹	--	death associated protein 3	82.86(n) 83.12(a)	295238 NM_001011950.1 NP_001011950.1
mouse (Mus musculus)	Dap3^{1, 5}	3 (43.40 cM)⁵	death associated protein 3^{1, 5}	83.12(n)¹ 82.1(a)¹	65111¹ NM_022994.2¹ NP_075370.1¹ AI464536⁵ AJ250375⁵ (see all 13)

About this table Species with no ortholog for DAP3

ENSEMBL Gene Tree for DAP3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/253 NCBI SNPs in DAP3 are shown (see all 253 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 33)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs12066633^1,2	F,H	153974968(+)	`AATATG/AGAAGG`	2	--	ng3¹ ese³		4	EU EA WA	416
--	rs1962247^1,2	A	153975345(-)	`cagtgG/Ctgcaa`	2	--	ng3¹ ese³		3	NA PA	252
	rs12096547^1,2	H	153962431(+)	`TTCCAG/AATGGT`	2	N/D	mis¹		4	EU EA WA	420
--	rs4933^1,2	C,F,H	153965742(+)	`GCTCTC/TTGGGG`	2	L/L	syn¹		5	MN EU EA WA	604
	rs540380^1,2	A,C,F,H,O	153958059(-)	`TCCCTC/TCAATT`	2	--	int¹		12	EA NA MN EU WA	896
	rs9427221^1,2	A,C,F,H	153936877(+)	`aacacA/Gtgata`	2	--	int¹		4	EU EA WA	414
	rs13376498^1,2	A,C,F,H	153961678(+)	`ACTGAG/ATAAAT`	2	--	int¹		7	EU EA WA NA	560
	rs552778^1,2	A,C,F,H	153953901(-)	`AAAAGC/TCTGTC`	2	--	int¹		3	EA WA	298
--	rs621181^1,2	A,C,F,H	153953856(-)	`AACTTG/ACCCAG`	2	--	int¹		4	EU EA WA	412
--	rs598176^1,2	A,C,F,H	153974177(-)	`TTTTCA/GATAGA`	2	--	int¹		6	EA NA EU WA	444

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HapMap Linkage Disequilibrium images for DAP3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602074

2 Novoseek disease relationships for DAP3 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
necrosis	11.58	2	9889192 (1)
tumors	0.00	2	9889192 (1)

About this table

Genetic Association Database: DAP3
Human Genome Epidemiology Navigator: DAP3 (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/38 PubMed articles for DAP3 gene (see all 38 ):

Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death. (PubMed id 7499268)^{1, 2, 3, 4} Kissil J.L....Kimchi A. (1995)
Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma. (PubMed id 15179560)^{1, 3, 6} Hirota T....Tamari M. (2004)
Assignment of death associated protein 3 (DAP3) to human chromosome 1q21 by in situ hybridization. (PubMed id 9284927)^{1, 2, 3} Kissil J.L. and Kimchi A. (1997)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{3, 4} Gregory S.G.... Bentley D.R. (2006)
The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)^{3, 4} Kenmochi N....Tanaka T. (2001)
The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. (PubMed id 11279123)^{3, 4} Cavdar Koc E....Spremulli L.L. (2001)
Functional role of death-associated protein 3 (DAP3) in anoikis. (PubMed id 15302871)^{1, 3} Miyazaki T....Reed J.C. (2004)
TRAIL-induced apoptosis is independent of the mitochondrial apoptosis mediator DAP3. (PubMed id 12359235)^{1, 3} Berger T. and Kretzler M. (2002)
Identification of phosphorylation sites in mammalian mitochondrial ribosomal protein DAP3. (PubMed id 18227431)^{1, 3} Miller J.L....Koc E.C. (2008)
hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis. (PubMed id 19103604)^{1, 3} Tang T....Farquhar M.G. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 7818	HGNC: 2673	AceView: DAP3	Ensembl:ENSG00000132676	euGenes: HUgn7818
ECgene: DAP3	H-InvDB: DAP3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for DAP3	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for DAP3
(Available from WIS Yeda, Salk, Tufts)

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Licensable Technologies for DAP3 gene:

Weizmann Institute:

DAP Kinase Gene Family: A Novel Target for Treatment of Neurodegenerative Disorders and Cancer

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for DAP3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DAP3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DAP3		Antibodies for DAP3
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DAP3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (DAP3)
	Antibodies (DAP3)
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	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Antibodies (DAP3)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for DAP3

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for DAP3

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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DAP3 Gene

protein-coding GIFtS: 66

Aliases &
Descriptions
for DAP3

Summaries
for DAP3

Genomic Location
for DAP3

Proteins
for DAP3

Protein Domains/
Families
for DAP3

Gene Function
for DAP3

Pathways & Interactions
for DAP3

Drugs & Compounds
for DAP3

Transcripts
for DAP3

Expression
for DAP3

Orthologs
for DAP3

Paralogs
for DAP3

SNPs/Variants
for DAP3

Disorders & Mutations
for DAP3

Medical News
for DAP3

Publications
for DAP3

Search for DAP3

Genome Databases showing DAP3

Other Databases showing DAP3

Specialized Databases showing DAP3

Licensable Technologies
for DAP3

Services
for DAP3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DAP3 Gene

protein-coding GIFtS: 66

Aliases & Descriptionsfor DAP3

Summariesfor DAP3

Genomic Locationfor DAP3

Proteinsfor DAP3

Protein Domains/Familiesfor DAP3

Gene Functionfor DAP3

Pathways & Interactionsfor DAP3

Drugs & Compoundsfor DAP3

Transcriptsfor DAP3

Expression for DAP3

Orthologsfor DAP3

Paralogsfor DAP3

SNPs/Variantsfor DAP3

Disorders & Mutationsfor DAP3

Medical Newsfor DAP3

Publicationsfor DAP3

Search for DAP3

Genome Databases showing DAP3

Other Databases showing DAP3

Specialized Databases showing DAP3

Licensable Technologiesfor DAP3

Servicesfor DAP3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DAP3

Summaries
for DAP3

Genomic Location
for DAP3

Proteins
for DAP3

Protein Domains/
Families
for DAP3

Gene Function
for DAP3

Pathways & Interactions
for DAP3

Drugs & Compounds
for DAP3

Transcripts
for DAP3

Expression
for DAP3

Orthologs
for DAP3

Paralogs
for DAP3

SNPs/Variants
for DAP3

Disorders & Mutations
for DAP3

Medical News
for DAP3

Publications
for DAP3

Licensable Technologies
for DAP3

Services
for DAP3