Aliases for DAOA Gene
External Ids for DAOA Gene
Previous GeneCards Identifiers for DAOA Gene
This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011]
GeneCards Summary for DAOA Gene
DAOA (D-Amino Acid Oxidase Activator) is a Protein Coding gene. Diseases associated with DAOA include childhood-onset schizophrenia and bipolar disorder. GO annotations related to this gene include enzyme binding and enzyme activator activity.
UniProtKB/Swiss-Prot for DAOA Gene
Seems to activate D-amino acid oxidase