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DAO Gene

protein-coding GIFtS: 60

GC12P107776

D-amino-acid oxidase
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
DAAO ^², ³
DAMOX ^¹, ², ³, ⁵
EC 1.4.3.3 ^³
MGC35381 ^²
OXDA ^²

Descriptions
D-amino-acid oxidase ^²

External Ids
HGNC: 2671¹
Entrez Gene: 1610²
UniProtKB: P14920³
Ensembl: ENSG00000110887⁷

Search outside databases for aliases for DAO gene

Previous GC identifers: GC12U990015 GC12P109154

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for DAO:

This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which

uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide

variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its

biological function is not known; it may act as a detoxifying agent which removes D-amino acids

that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor.

This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq]

UniProtKB/Swiss-Prot: OXDA_HUMAN, P14920

Function: Regulates the level of the neuromodulator D-serine in the brain. Has high activity

towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which

removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a

preference for those having small hydrophobic side chains followed by those bearing polar,

aromatic, and basic groups. Does not act on acidic amino acids

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DAO gene

Entrez Gene cytogenetic band: 12q24 Ensembl cytogenetic band: 12q24.11 HGNC chromosome: 12

DAO Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P107776: (about GC identifiers)

Start:	107,797,986 bp from pter
End:	107,818,839 bp from pter
Size:	20,854 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000012.10 NT_019546.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: OXDA_HUMAN, P14920 (See protein sequence)

Recommended Name: D-amino-acid oxidase

Size: 347 amino acids; 39474 Da

Cofactor: FAD

Subunit: Homodimer

Subcellular location: Peroxisome

PDB structures from and Proteopedia :

2DU8 (3D)

2E48 (3D)

2E49 (3D)

2E4A (3D)

2E82 (3D)

2GNZ (3D)

3CUK (3D)

Secondary accessions: Q16758 Q8N6R2

REFSEQ proteins: NP_001908.3

ENSEMBL proteins:

ENSP00000228476

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (D Amino Acid Oxidase)
	Human Recombinant Proteins from Abnova (DAO)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005777	peroxisome	NAS	2901986

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Antibodies for DAO:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for DAO
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (D Amino Acid Oxidase), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (DAO)
	Novus Biologicals Antibodies for DAO

Assays for DAO:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P14920

ProtoNet protein and cluster: P14920

1 Blocks protein family: IPB006181 D-amino acid oxidase

UniProtKB/Swiss-Prot: OXDA_HUMAN, P14920

Similarity: Belongs to the DAMOX/DASOX family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAO)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DAO)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001917

Applied Biosystems Silencer® siRNAs for DAO

Sigma-Aldrich siRNA and siRNA Panels for DAO

Sigma-Aldrich shRNA for DAO

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for DAO
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001917
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001917
untagged cDNA clones in CMV expression vector (see all 2): NM_001917

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001917

UniProtKB/Swiss-Prot: OXDA_HUMAN, P14920

Function: Regulates the level of the neuromodulator D-serine in the brain. Has high activity

towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which

removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a

preference for those having small hydrophobic side chains followed by those bearing polar,

aromatic, and basic groups. Does not act on acidic amino acids

Catalytic activity: A D-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2)

Biophysicochemical properties: Kinetic parameters: KM=3.6 mM for D-serine; KM=1.7 mM for D-proline;

KM=1.1 mM for D-tyrosine; KM=1.5 mM for D-DOPA; KM=1.2 mM for D-phenylalanine; KM=0.9 mM for

D-alanine;

Enzyme Number (IUBMB): EC 1.4.3.3

Genatlas biochemistry entry for DAO:

D-amino-oxidase,glycine oxidase catalyzing the synthesis of glyoxylate,peroxisomal

3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Dao):

behavior/neurological

homeostasis/metabolism

nervous system

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003884	D-amino-acid oxidase activity	TAS	1356107
GO:0005488	binding	IEA	--
GO:0016491	oxidoreductase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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3 Sigma-Aldrich "Your Favorite Gene" Pathways for DAO (Your Favorite Gene powered by Ingenuity)

Arginine and Proline Metabolism
Glycine, Serine and Threonine Metabolism
D-arginine and D-ornithine Metabolism

GeneDecks DAO for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for DAO

5/18 Interacting proteins for DAO (ENSP00000228476³) via UniProtKB, MINT, and/or STRING (see all 18 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HAO1	ENSP00000368066³	STRING (score=.926)
PIPOX	ENSP00000317721³	STRING (score=.905)
AGXT	ENSP00000302620³	STRING (score=.899)
ALAS1	ENSP00000309259³	STRING (score=.899)
ALAS2	ENSP00000332369³	STRING (score=.899)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006551	leucine metabolic process	IEA	--
GO:0055114	oxidation reduction	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for DAO
10/28 Novoseek chemical compound relationships for DAO gene (see all 28 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
glutaryl-7-aminocephalosporanic acid	77.68	6	15269545 (2), 10972935 (1), 16809100 (1)
7-aminocephalosporanic acid	77.59	11	15269545 (3), 12024974 (2), 10972935 (1), 16809100 (1)
flavin	75.52	38	9153426 (3), 17088322 (3), 8690726 (3), 10716694 (2) (see all 14)
cephalosporin c	71.50	6	15269545 (3), 16809100 (1)
pipecolic acid	70.21	5	11330064 (3), 8892018 (1)
trigonelline	63.78	8	1975807 (3), 10920257 (1)
alpha-ketoisovalerate	62.34	2	1682335 (1), 9153426 (1)
cerium	61.84	4	1682047 (2), 1347269 (1), 7907383 (1)
flavin-adenine dinucleotide	61.66	4	8782713 (2), 1431554 (1), 7785760 (1)
riboflavin	44.96	1	1971765 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAO)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DAO)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001917

Sigma-Aldrich siRNA and siRNA Panels for DAO

Sigma-Aldrich shRNA for DAO

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001917

REFSEQ mRNAs for DAO gene:

NM_001917.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001917

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001917
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001917
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_001917

Additional cDNA sequence:

AK312995.1 BC029057.1 BC074770.2 BX538210.1

4 DOTS entries:

DT.406423 DT.101980700 DT.92419491 DT.95086560

24/38 AceView cDNA sequences (see all 38 ):

BC029057 AX776478 BX538210 BE463940 AI791352 AI478185 AV727558 BM685098

AX776479 AX786386 BF115205 BC074770 AI470939 AX776480 BX115127 BM717775

AI732956 BM679799 BE464053 AA953563 AW299839 AW299997 BF593275 BX488551

highest scoring ESTs for DAO:

AA863145 AA953563 AI470939 AI478185 AI492427 AW299839 AW299997 AW779822 BC029057 BE463682

Unigene Cluster for DAO:

D-amino-acid oxidase

Hs.113227 [show with all ESTs]

Unigene Representative Sequence: NM_001917

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000228476

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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DAO expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DAO

¹ / ² / ³

3 probe-sets matching DAO gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34464_at²^{, 3}	U95-A	1	0.94	1.00	1.00	1.00	X13227	0.80	1.00	0.91	1
206878_at²^{, 3}	U133-A	1	0.91	1.00	--	--	NM_001917	0.60	1.00	0.82	1
206878_at²	U133Plus2	1	0.91	1.00	--	--	--	--	--	--	--

GeneDecks DAO for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AGTCTTCAGA

SOURCE GeneReport for Unigene cluster: Hs.113227
Expression variation in blood from EXPOLDB for DAO

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DAO gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DAO¹	--	D-amino-acid oxidase	87.13(n) 83.29(a)	486317 XM_543443.2 XP_543443.2
chimpanzee (Pan troglodytes)	DAO¹	--	D-amino-acid oxidase	98.85(n) 97.84(a)	743881 XM_001164209.1 XP_001164209.1
cow (Bos taurus)	DAO¹	--	D-amino-acid oxidase	87.8(n) 83.29(a)	615334 XM_867833.1 XP_872926.1
rat (Rattus norvegicus)	Dao¹	--	D-amino-acid oxidase	82.47(n) 80.64(a)	114027 NM_053626.1 NP_446078.1
mouse (Mus musculus)	Dao^{1, 5}	5 (65.00 cM)⁵	D-amino acid oxidase^{1, 5}	82.13(n)¹ 80.87(a)¹	13142¹ NM_010018.2¹ NP_034148.2¹ AI530495⁵ AI987963⁵ (see all 13)

About this table Species with no ortholog for DAO

ENSEMBL Gene Tree for DAO

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for DAO gene

DDO²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/174 NCBI SNPs in DAO are shown (see all 174 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 42)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs4623951^1,2	A,C,F,H	107796180(+)	`AAGGGT/CCATAT`	1	--	ng5¹		8		EU EA WA NA	574
--	rs10861973^1,2	A,C,F,H	107796057(+)	`ACACCA/GCAATT`	1	--	ng5¹		3		EU EA	300
--	rs11114081^1,2	F,H	107797496(+)	`CTTGCA/GTCTCT`	1	--	ng5¹		3		EU EA	300
--	rs7965821^1,2	A,C	107796816(+)	`tgatcC/Tatcca`	1	--	ng5¹		0	--	--	--	--
--	rs4262766^1,2	H	107818388(-)	`TTCTAC/ACAAAG`	1	V/G	mis¹		4		EU EA WA	358
	rs1053875^1,2	H	107818720(+)	`AGAAAA/GTCAAA`	1	--	ut3¹		3		EA WA	298
	rs7980427^1,2	C,F,H	107805439(+)	`ATCTCG/AGGCTA`	1	S/S	syn¹ ese³		8		NA EU EA WA	618
--	rs4644682^1,2	H	107818389(-)	`ATTCTC/AACAAA`	1	G/G	syn¹		4		EU EA WA	406
--	rs2111902^1,2	A,C,F,H,O	107802876(+)	`tgatgT/GtgTGC`	1	--	int¹		12		NA EU EA WA	1464
	rs3741775^1,2	A,C,F,H	107807732(-)	`GGAAGT/GCACTT`	1	--	int¹		9		NA EU EA WA	1310

About this table

HapMap Linkage Disequilibrium images for DAO (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 124050 disorders: 181500

9 Novoseek disease relationships for DAO gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
hypofunction	73.20	2	12625025 (1), 18378121 (1)
schizophrenia	71.39	121	17492767 (7), 18378121 (7), 16842973 (6), 17880399 (4) (see all 31)
bipolar disorder	51.25	10	18165970 (3), 14966479 (2), 18378121 (2), 16203746 (1) (see all 5)
zellweger syndrome	45.50	1	11330064 (1)
psychiatric disorder	5.16	2	16183301 (1)
tumors	4.59	1	14735461 (1)
nephrotic syndrome	4.36	3	9582550 (2)
renal disease	0.00	2	8496288 (1), 9582550 (1)
cancer	0.00	2	15651667 (1), 12564842 (1)

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Genetic Association Database: DAO
Human Genome Epidemiology Navigator: DAO (40 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

Canada Approves First Pacemaker, Integrity AFx DR Model 5346, Proven to Suppress Atrial Fibrillation

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/150 PubMed articles for DAO gene (see all 150 ):

Molecular cloning and chromosomal localization of a human gene encoding D-amino-acid oxidase. (PubMed id 1356107)^{1, 2, 3, 4} Fukui K. and Miyake Y. (1992)
Crystal structure of human D-amino acid oxidase: context-dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the si-face of the flavin ring. (PubMed id 17088322)^{1, 3, 4} Kawazoe T....Fukui K. (2006)
Association of DAAO with schizophrenia in the Chinese population. (PubMed id 15464270)^{1, 3, 6} Liu X....He L. (2004)
Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. (PubMed id 16380905)^{1, 3, 6} Fallin M.D....Pulver A.E. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter. (PubMed id 8182053)^{2, 3} Chassande O....Lazdunski M. (1994)
Molecular cloning and sequence analysis of cDNA encoding human kidney D-amino acid oxidase. (PubMed id 2901986)^{3, 4} Momoi K.... Miyake Y. (1988)
D-amino acid oxidase (DAO) genotype and mood symptomatology in schizophrenia. (PubMed id 17890006)^{1, 3} Corvin A....Gill M. (2007)
Evidence for association and epistasis at the DAOA/G30 and D-amino acid oxidase loci in an Irish schizophrenia sample. (PubMed id 17492767)^{1, 3} Corvin A....Gill M. (2007)
Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. (PubMed id 12364586)^{1, 3} Chumakov I.... Cohen D. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 1610	HGNC: 2671	AceView: DAO	Ensembl:ENSG00000110887	euGenes: HUgn1610
ECgene: DAO	H-InvDB: DAO

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for DAO
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for DAO:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DAO-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DAO		Antibodies for DAO
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DAO		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (DAO)
	Antibodies (DAO)
	Chimera RNAi (DAO)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (D Amino Acid Oxidase)
	Antibodies (D Amino Acid Oxidase)

Search OriGene for DAO

Search Tocris compounds for DAO

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for DAO

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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DAO Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for DAO

Summaries
for DAO

Genomic Location
for DAO

Proteins
for DAO

Protein Domains/
Families
for DAO

Gene Function
for DAO

Pathways & Interactions
for DAO

Drugs & Compounds
for DAO

Transcripts
for DAO

Expression
for DAO

Orthologs
for DAO

Paralogs
for DAO

SNPs/Variants
for DAO

Disorders & Mutations
for DAO

Medical News
for DAO

Publications
for DAO

Search for DAO

Genome Databases showing DAO

Other Databases showing DAO

Specialized Databases showing DAO

Licensable Technologies
for DAO

Services
for DAO

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DAO Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor DAO

Summariesfor DAO

Genomic Locationfor DAO

Proteinsfor DAO

Protein Domains/Familiesfor DAO

Gene Functionfor DAO

Pathways & Interactionsfor DAO

Drugs & Compoundsfor DAO

Transcriptsfor DAO

Expression for DAO

Orthologsfor DAO

Paralogsfor DAO

SNPs/Variantsfor DAO

Disorders & Mutationsfor DAO

Medical Newsfor DAO

Publicationsfor DAO

Search for DAO

Genome Databases showing DAO

Other Databases showing DAO

Specialized Databases showing DAO

Licensable Technologiesfor DAO

Servicesfor DAO

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DAO

Summaries
for DAO

Genomic Location
for DAO

Proteins
for DAO

Protein Domains/
Families
for DAO

Gene Function
for DAO

Pathways & Interactions
for DAO

Drugs & Compounds
for DAO

Transcripts
for DAO

Expression
for DAO

Orthologs
for DAO

Paralogs
for DAO

SNPs/Variants
for DAO

Disorders & Mutations
for DAO

Medical News
for DAO

Publications
for DAO

Licensable Technologies
for DAO

Services
for DAO