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Aliases for DANCR Gene

Subcategory (RNA class) for DANCR Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for DANCR Gene

  • Differentiation Antagonizing Non-Protein Coding RNA 2 3 4 5
  • KIAA0114 2 3 4
  • Small Nucleolar RNA Host Gene 13 (Non-Protein Coding) 2 3
  • Adipogenesis Up-Regulated Transcript 2 2 3
  • Anti-Differentiation Noncoding RNA 2 3
  • Anti-Differentiation NcRNA 2 3
  • SNHG13 3 4
  • ANCR 3 4
  • Small Nucleolar RNA Host Gene Protein 13 4
  • Anti-Differentiation NcRNA Protein 4
  • LncRNA-ANCR 3
  • AGU2 3

External Ids for DANCR Gene

Previous HGNC Symbols for DANCR Gene

  • KIAA0114
  • SNHG13

Previous GeneCards Identifiers for DANCR Gene

  • GC04P053582
  • GC04P053584
  • GC04P053588

Summaries for DANCR Gene

Entrez Gene Summary for DANCR Gene

  • This gene produces a long non-coding RNA that functions as a negative regulator of cell differentiation. This transcript associates with enhancer of zeste homolog 2 to repress expression of the runt related transcription factor 2 gene. Increased expression of this transcript may be associated with cancer. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Dec 2016]

GeneCards Summary for DANCR Gene

DANCR (Differentiation Antagonizing Non-Protein Coding RNA) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DANCR Gene

Genomics for DANCR Gene

Regulatory Elements for DANCR Gene

Enhancers for DANCR Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F052841 1.1 Ensembl ENCODE 17.7 +130.5 130498 2.6 ZNF217 CTCF REST RAD21 SPI1 DANCR ENSG00000212490 ERVMER34-1 SNORA26 RASL11B GC04M052856 GC04P052827
GH04F052735 0.4 ENCODE 11.4 +22.8 22845 0.2 CTCF ZNF687 TEAD4 SIN3A REST DPF2 MNT ZNF2 TEAD3 CTBP1 DANCR SNORA26 ENSG00000248375 GC04P052749
GH04F052640 0.8 Ensembl ENCODE 11.2 -69.8 -69846 4.1 PKNOX1 TBL1XR1 CREB3L1 NFRKB INSM2 BMI1 FEZF1 RAD21 ZBTB40 YY1 USP46 DANCR SNORA26 RNU6-1252P
GH04F052711 0.6 ENCODE 11 +1.2 1197 4.7 HDGF PKNOX1 CREB3L1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 YY1 DANCR GC04P052716 ENSG00000248375
GH04F052912 1 Ensembl ENCODE 10.6 +201.9 201932 3.7 ELF3 SOX13 SAP130 ZNF792 CEBPG FOS CREM MAFK HOMEZ GATAD2A DANCR SNORA26 USP46 LOC101928658 GC04M052884
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around DANCR on UCSC Golden Path with GeneCards custom track

Promoters for DANCR Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001859566 296 1801 HDGF PKNOX1 CREB3L1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 YY1
ENSR00001240998 1696 201 SOX13 POLR2A TEAD1 CEBPA BCL6 NR2F6

Genomic Location for DANCR Gene

Chromosome:
4
Start:
52,712,404 bp from pter
End:
52,720,351 bp from pter
Size:
7,948 bases
Orientation:
Plus strand

Genomic View for DANCR Gene

Genes around DANCR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DANCR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DANCR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DANCR Gene

Proteins for DANCR Gene

  • Protein details for DANCR Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C864-DANCR_HUMAN
    Recommended name:
    Putative uncharacterized protein DANCR
    Protein Accession:
    P0C864
    Secondary Accessions:
    • A0A024RD90

    Protein attributes for DANCR Gene

    Size:
    163 amino acids
    Molecular mass:
    16785 Da
    Quaternary structure:
    No Data Available

neXtProt entry for DANCR Gene

Post-translational modifications for DANCR Gene

No Post-translational modifications

No data available for DME Specific Peptides for DANCR Gene

Domains & Families for DANCR Gene

Gene Families for DANCR Gene

Protein Domains for DANCR Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DANCR: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for DANCR Gene

Function for DANCR Gene

Phenotypes for DANCR Gene

GenomeRNAi human phenotypes for DANCR:
genes like me logo Genes that share phenotypes with DANCR: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DANCR Gene

Localization for DANCR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for DANCR Gene

Pathways & Interactions for DANCR Gene

SuperPathways for DANCR Gene

No Data Available

Interacting Proteins for DANCR Gene

Gene Ontology (GO) - Biological Process for DANCR Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DANCR Gene

Transcripts for DANCR Gene

mRNA/cDNA for DANCR Gene

(4) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for DANCR Gene

Differentiation antagonizing non-protein coding RNA:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DANCR Gene

No ASD Table

Relevant External Links for DANCR Gene

GeneLoc Exon Structure for
DANCR
ECgene alternative splicing isoforms for
DANCR

Expression for DANCR Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for DANCR Gene

NURSA nuclear receptor signaling pathways regulating expression of DANCR Gene:

DANCR

SOURCE GeneReport for Unigene cluster for DANCR Gene:

Hs.744077

mRNA Expression by UniProt/SwissProt for DANCR Gene:

P0C864-DANCR_HUMAN
Tissue specificity: Expressed in keratinocytes.
genes like me logo Genes that share expression patterns with DANCR: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for DANCR Gene

Orthologs for DANCR Gene

Evolution for DANCR Gene

ENSEMBL:
Gene Tree for DANCR (if available)
TreeFam:
Gene Tree for DANCR (if available)

No data available for Orthologs for DANCR Gene

Paralogs for DANCR Gene

No data available for Paralogs for DANCR Gene

Variants for DANCR Gene

Sequence variations from dbSNP and Humsavar for DANCR Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs10028122 -- 52,711,842(+) CTCCA(A/G)CTGAT downstream-variant-500B, upstream-variant-2KB
rs10033218 -- 52,714,027(+) TGACT(A/G)ACAAC intron-variant, nc-transcript-variant
rs111894957 -- 52,712,616(+) TCGCC(C/T)GGTGT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs113985786 -- 52,712,432(+) GGGCC(C/T)CGCGA nc-transcript-variant, upstream-variant-2KB
rs116127390 -- 52,710,636(+) TGCTA(A/G)GTTGC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for DANCR Gene

Variant ID Type Subtype PubMed ID
nsv472482 CNV novel sequence insertion 20440878
nsv524494 CNV loss 19592680
nsv594201 CNV loss 21841781

Relevant External Links for DANCR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DANCR

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DANCR Gene

Disorders for DANCR Gene

Relevant External Links for DANCR

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
DANCR

No disorders were found for DANCR Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DANCR Gene

Publications for DANCR Gene

  1. Suppression of progenitor differentiation requires the long noncoding RNA ANCR. (PMID: 22302877) Kretz M. … Khavari P.A. (Genes Dev. 2012) 2 3 4 64
  2. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 7788527) Nagase T. … Nomura N. (DNA Res. 1995) 2 3 4 64
  3. Transcripts of unknown function in multiple-signaling pathways involved in human stem cell differentiation. (PMID: 19531736) Kikuchi K. … Aizawa Y. (Nucleic Acids Res. 2009) 2 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. (PMID: 11752456) Xu X.R. … Han Z.G. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3 4 64

Products for DANCR Gene

Sources for DANCR Gene

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