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Aliases for DALRD3 Gene

Aliases for DALRD3 Gene

  • DALR Anticodon Binding Domain Containing 3 2 3

External Ids for DALRD3 Gene

Previous GeneCards Identifiers for DALRD3 Gene

  • GC03M049029
  • GC03M049055
  • GC03M049059
  • GC03M049062
  • GC03M049063
  • GC03M049064
  • GC03M049065
  • GC03M049066
  • GC03M049068
  • GC03M049073
  • GC03M049076

Summaries for DALRD3 Gene

Entrez Gene Summary for DALRD3 Gene

  • The exact function of this gene is not known. It encodes a protein with a DALR anticodon binding domain similar to that of class Ia aminoacyl tRNA synthetases. This gene is located in a cluster of genes (with a complex sense-anti-sense genome architecture) on chromosome 3, and contains two micro RNA (miRNA) precursors (mir-425 and mir-191) in one of its introns. Preferential expression of this gene (the miRNAs and other genes in the cluster) in testis suggests a role of this gene in spermatogenesis (PMID:19906709). [provided by RefSeq, Feb 2013]

GeneCards Summary for DALRD3 Gene

DALRD3 (DALR Anticodon Binding Domain Containing 3) is a Protein Coding gene. GO annotations related to this gene include arginine-tRNA ligase activity.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DALRD3 Gene

Genomics for DALRD3 Gene

Regulatory Elements for DALRD3 Gene

Genomic Location for DALRD3 Gene

Start:
49,015,399 bp from pter
End:
49,022,293 bp from pter
Size:
6,895 bases
Orientation:
Minus strand

Genomic View for DALRD3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for DALRD3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DALRD3 Gene

Proteins for DALRD3 Gene

  • Protein details for DALRD3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5D0E6-DALD3_HUMAN
    Recommended name:
    DALR anticodon-binding domain-containing protein 3
    Protein Accession:
    Q5D0E6
    Secondary Accessions:
    • Q7Z5S7
    • Q86WY1
    • Q8N105
    • Q8NA89
    • Q9NVU8

    Protein attributes for DALRD3 Gene

    Size:
    543 amino acids
    Molecular mass:
    59363 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for DALRD3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for DALRD3 Gene

Proteomics data for DALRD3 Gene at MOPED

Post-translational modifications for DALRD3 Gene

  • Ubiquitination at Lys219
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for DALRD3 Gene

Domains for DALRD3 Gene

Protein Domains for DALRD3 Gene

Suggested Antigen Peptide Sequences for DALRD3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with DALRD3: view

No data available for Gene Families and UniProtKB/Swiss-Prot for DALRD3 Gene

Function for DALRD3 Gene

Gene Ontology (GO) - Molecular Function for DALRD3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding --
GO:0004812 aminoacyl-tRNA ligase activity --
GO:0004814 arginine-tRNA ligase activity IEA --
GO:0005515 protein binding IPI 25416956
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with DALRD3: view

miRNA for DALRD3 Gene

miRTarBase miRNAs that target DALRD3

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for DALRD3 Gene

Localization for DALRD3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for DALRD3 Gene COMPARTMENTS Subcellular localization image for DALRD3 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for DALRD3 Gene

Pathways for DALRD3 Gene

SuperPathways for DALRD3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for DALRD3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006418 tRNA aminoacylation for protein translation --
GO:0006420 arginyl-tRNA aminoacylation IEA --
genes like me logo Genes that share ontologies with DALRD3: view

No data available for Pathways by source for DALRD3 Gene

Transcripts for DALRD3 Gene

Unigene Clusters for DALRD3 Gene

DALR anticodon binding domain containing 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for DALRD3 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c ^ 12a · 12b ^ 13
SP1:
SP2: -
SP3: - -
SP4: -
SP5:
SP6: -
SP7:

Relevant External Links for DALRD3 Gene

GeneLoc Exon Structure for
DALRD3
ECgene alternative splicing isoforms for
DALRD3

Expression for DALRD3 Gene

mRNA expression in normal human tissues for DALRD3 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for DALRD3 Gene

SOURCE GeneReport for Unigene cluster for DALRD3 Gene Hs.708076

genes like me logo Genes that share expressions with DALRD3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for DALRD3 Gene

Orthologs for DALRD3 Gene

This gene was present in the common ancestor of animals.

Orthologs for DALRD3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia DALRD3 35
  • 81.1 (n)
  • 77.88 (a)
DALRD3 36
  • 71 (a)
OneToOne
dog
(Canis familiaris)
Mammalia DALRD3 35
  • 83.03 (n)
  • 79.7 (a)
DALRD3 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Dalrd3 35
  • 79.8 (n)
  • 78.25 (a)
Dalrd3 16
Dalrd3 36
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia DALRD3 36
  • 57 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia DALRD3 36
  • 44 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Dalrd3 35
  • 79.62 (n)
  • 78.25 (a)
chicken
(Gallus gallus)
Aves DALRD3 35
  • 62.82 (n)
  • 56.03 (a)
DALRD3 36
  • 55 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia DALRD3 36
  • 45 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dalrd3 35
  • 53.35 (n)
  • 45.44 (a)
dalrd3 36
  • 39 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG8097 36
  • 22 (a)
OneToOne
Species with no ortholog for DALRD3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for DALRD3 Gene

ENSEMBL:
Gene Tree for DALRD3 (if available)
TreeFam:
Gene Tree for DALRD3 (if available)

Paralogs for DALRD3 Gene

No data available for Paralogs for DALRD3 Gene

Variants for DALRD3 Gene

Sequence variations from dbSNP and Humsavar for DALRD3 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs3087866 - 49,017,259(-) TTGGC(A/G)GAAGT reference, missense, nc-transcript-variant
rs3923475 -- 49,018,355(+) GGCAC(C/G/T)GGGCC intron-variant, synonymous-codon, reference, nc-transcript-variant
rs11542202 -- 49,018,239(-) GACCC(A/C)CGCGG missense, reference, utr-variant-5-prime, nc-transcript-variant
rs61743083 -- 49,017,639(+) GGTCA(C/T)AGCCA reference, missense, nc-transcript-variant
rs71324930 -- 49,016,883(+) GTTGG(C/T)GCTAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for DALRD3 Gene

Variant ID Type Subtype PubMed ID
nsv876764 CNV Loss 21882294

Relevant External Links for DALRD3 Gene

HapMap Linkage Disequilibrium report
DALRD3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DALRD3 Gene

Disorders for DALRD3 Gene

No disorders were found for DALRD3 Gene.

No data available for UniProtKB/Swiss-Prot for DALRD3 Gene

Publications for DALRD3 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Integrative analysis of the human cis-antisense gene pairs, miRNAs and their transcription regulation patterns. (PMID: 19906709) Grinchuk O.V. … Kuznetsov V.A. (Nucleic Acids Res. 2010) 3

Products for DALRD3 Gene

Sources for DALRD3 Gene

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