V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

DALRD3 Gene

protein-coding GIFtS: 44

GC03M049029

DALR anticodon binding domain containing 3
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FLJ10496 ^¹, ²

Descriptions
DALR anticodon binding domain containing 3 ^²

External Ids
HGNC: 25536¹
Entrez Gene: 55152²
UniProtKB: Q5D0E6³
Ensembl: ENSG00000178149⁷

Search outside databases for aliases for DALRD3 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DALRD3 gene

Entrez Gene cytogenetic band: 3p21.31 Ensembl cytogenetic band: 3p21.31 HGNC cytogenetic band: 3p21.31

DALRD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03M049029: (about GC identifiers)

Start:	49,027,439 bp from pter
End:	49,033,471 bp from pter
Size:	6,033 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000003.10 NT_022517.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: DALD3_HUMAN, Q5D0E6 (See protein sequence)

Recommended Name: DALR anticodon-binding domain-containing protein 3

Size: 543 amino acids; 59391 Da

Secondary accessions: Q7Z5S7 Q86WY1 Q8N105 Q8NA89 Q9NVU8

Alternative splicing: 4 isoforms: Q5D0E6-1 Q5D0E6-2 Q5D0E6-3 Q5D0E6-4

REFSEQ proteins (2 alternative transcripts):

NP_001009996.1 NP_060584.3

ENSEMBL proteins:

ENSP00000378846 ENSP00000323265 ENSP00000344989

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (DALRD3)
	Human Recombinant Proteins from Abnova (DALRD3)

OriGene Purified Recombinant Human Protein: DALRD3

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--

About this table

Antibodies for DALRD3:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (DALRD3), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (DALRD3)
	Novus Biologicals Antibody for DALRD3

Assays for DALRD3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q5D0E6

ProtoNet protein and cluster: Q5D0E6

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DALRD3)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_018114

Applied Biosystems Silencer® siRNAs for DALRD3

Sigma-Aldrich siRNA for DALRD3

Sigma-Aldrich shRNA for DALRD3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for DALRD3
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001009996
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001009996
untagged cDNA clones in CMV expression vector (see all 2): NM_001009996

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001009996

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0004814	arginine-tRNA ligase activity	IEA	--
GO:0005524	ATP binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006420	arginyl-tRNA aminoacylation	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for DALRD3

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DALRD3)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_018114

Sigma-Aldrich siRNA for DALRD3

Sigma-Aldrich shRNA for DALRD3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001009996 NM_018114

REFSEQ mRNAs for DALRD3 gene (2 alternative transcripts):

NM_001009996.1 NM_018114.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001009996 NM_018114

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001009996
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001009996
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_001009996

Additional cDNA sequence:

AK001358.1 AK093204.1 AK093294.1 AK301352.1 AK308273.1 BC014099.2 BC032440.1 BC047683.1

BC054493.1 BX648719.1

24/43 DOTS entries (see all 43 ):

DT.40107524 DT.120852614 DT.100871177 DT.95314332 DT.95259800 DT.100654638 DT.100644682 DT.91932300

DT.100654637 DT.100654641 DT.95152922 DT.100654644 DT.86859941 DT.100646769 DT.97861939 DT.86836253

DT.120852525 DT.92437664 DT.100654643 DT.120852415 DT.100810143 DT.40133097 DT.95289841 DT.95259889

24/304 AceView cDNA sequences (see all 304 ):

CD370622 AW204768 AA766527 AA747665 CA393762 BX116502 BM783310 BM783076

BI912394 BF340990 AI553735 AI951656 BC014099 CA388881 BI517346 BQ427440

BM700040 BC054493 AW469977 AI858995 BP371220 BM476341 BC047683 BI829571

highest scoring ESTs for DALRD3:

AA429081 W22712 AA010403 AA094866 AA102039 AA172135 AA248734 AA253248 AA281891 AA349379

Unigene Cluster for DALRD3:

DALR anticodon binding domain containing 3

Hs.708076 [show with all ESTs]

Unigene Representative Sequence: NM_018114

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for DALRD3 (see all 7 )

ExUns:	1	^	2a	·	2b	·	2c	^	3a	·	3b	^	4a	·	4b	·	4c	^	5a	·	5b	·	5c	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11a	·	11b	·	11c	^	12a	·	12b	^	13
SP1:
SP2:																																			-
SP3:																																			-		-
SP4:																											-
SP5:

About this scheme

ECgene alternative splicing isoforms for DALRD3

3 Ensembl transcripts including schematic representations:

ENST00000395462 ENST00000313778 ENST00000341949

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

DALRD3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DALRD3

¹ / ² / ³

7 probe-sets matching DALRD3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
91611_at²^{, 3}	U95-D	1	1.00	1.00	0.43	1.12	AI951656	0.60	1.00	0.82	1
65570_i_at²^{, 3}	U95-C	1	1.00	1.00	0.90	0.71	AA429081	0.80	1.00	0.91	1
65569_s_at²^{, 3}	U95-C	1	1.00	1.00	0.85	1.18	W22712	0.80	1.00	0.91	1
221934_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BF941492	0.60	1.00	0.82	1
218808_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_018114	0.60	1.00	0.82	1
221934_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
218808_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks DALRD3 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.708076

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DALRD3 gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DALRD3¹	--	DALR anticodon binding domain containing 3	83.03(n) 79.7(a)	484772 XM_541888.2 XP_541888.2
chimpanzee (Pan troglodytes)	DALRD3¹	--	DALR anticodon binding domain containing 3	96.06(n) 95.03(a)	460358 XM_530602.2 XP_530602.2
rat (Rattus norvegicus)	Dalrd3¹	--	DALR anticodon binding domain containing 3	79.62(n) 78.25(a)	363146 NM_001014214.1 NP_001014236.1
mouse (Mus musculus)	Dalrd3^{1, 5}	9⁵	DALR anticodon binding domain containing 3^{1, 5}	79.8(n)¹ 78.25(a)¹	67789¹ NM_026378.3¹ NP_080654.3¹ AI841825⁵ AK002439⁵ (see all 17)
chicken (Gallus gallus)	DALRD3¹	--	DALR anticodon binding domain containing 3	63.89(n) 57.26(a)	416059 XM_414397.2 XP_414397.2

About this table Species with no ortholog for DALRD3

ENSEMBL Gene Tree for DALRD3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

5 NCBI SNPs in DALRD3 are shown
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (only AB snps)

AB	SNP ID	Valid	Chr 3 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs3087866^1,2	A,C,F,H	49029696(-)	`TTGGCG/AGAAGT`	2	R/Q	mis¹ ese³		12		MN EU EA WA NA	1134
--	rs11542202^1,2	--	49030676(-)	`GACCCA/CCGCGG`	2	P/H	mis¹ ut5¹ ese³		0	--	--	--	--
--	rs61743083^1,2	--	49030076(+)	`GGTCAA/GAGCCA`	4	Y/S Y/F	mis¹		0	--	--	--	--
--	rs71324930^1,2	--	49029320(+)	`GTTGGC/TGCTAC`	2	--	int¹		0	--	--	--	--
	rs3923475^1,2	--	49030792(+)	`GGCACG/TGGGCC`	2	--	int¹		0	--	--	--	--

About this table
The following additional 14 SNP(s) have been found in Applied Biosystems data source:

(Click for Applied Biosystems TaqMan ® Genotyping Assay)

rs1134122	rs62621815	rs13316620	rs11706445	rs11557545	rs11557543	rs8926
rs3929973	rs3923476	rs11557541	rs11706052	rs7624225	rs7100	rs12637996

HapMap Linkage Disequilibrium images for DALRD3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

4 PubMed articles for DALRD3 gene:

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{2, 3} Strausberg R.L....Marra M.A. (2002)
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)³ Brandenberger R.... Stanton L.W. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)⁴ Gerhard D.S....Malek J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 55152	HGNC: 25536	AceView: FLJ10496	Ensembl:ENSG00000178149	euGenes: HUgn55152
ECgene: DALRD3	H-InvDB: DALRD3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for DALRD3
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for DALRD3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DALRD3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DALRD3		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DALRD3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (DALRD3)
	Antibodies (DALRD3)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (DALRD3)
	Antibodies (DALRD3)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for DALRD3

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for DALRD3

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
DALRD3 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

DALRD3 Gene

protein-coding GIFtS: 44

Aliases &
Descriptions
for DALRD3

Summaries
for DALRD3

Genomic Location
for DALRD3

Proteins
for DALRD3

Protein Domains/
Families
for DALRD3

Gene Function
for DALRD3

Pathways & Interactions
for DALRD3

Drugs & Compounds
for DALRD3

Transcripts
for DALRD3

Expression
for DALRD3

Orthologs
for DALRD3

Paralogs
for DALRD3

SNPs/Variants
for DALRD3

Disorders & Mutations
for DALRD3

Medical News
for DALRD3

Publications
for DALRD3

Search for DALRD3

Genome Databases showing DALRD3

Other Databases showing DALRD3

Specialized Databases showing DALRD3

Licensable Technologies
for DALRD3

Services
for DALRD3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DALRD3 Gene

protein-coding GIFtS: 44

Aliases & Descriptionsfor DALRD3

Summariesfor DALRD3

Genomic Locationfor DALRD3

Proteinsfor DALRD3

Protein Domains/Familiesfor DALRD3

Gene Functionfor DALRD3

Pathways & Interactionsfor DALRD3

Drugs & Compoundsfor DALRD3

Transcriptsfor DALRD3

Expression for DALRD3

Orthologsfor DALRD3

Paralogsfor DALRD3

SNPs/Variantsfor DALRD3

Disorders & Mutationsfor DALRD3

Medical Newsfor DALRD3

Publicationsfor DALRD3

Search for DALRD3

Genome Databases showing DALRD3

Other Databases showing DALRD3

Specialized Databases showing DALRD3

Licensable Technologiesfor DALRD3

Servicesfor DALRD3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DALRD3

Summaries
for DALRD3

Genomic Location
for DALRD3

Proteins
for DALRD3

Protein Domains/
Families
for DALRD3

Gene Function
for DALRD3

Pathways & Interactions
for DALRD3

Drugs & Compounds
for DALRD3

Transcripts
for DALRD3

Expression
for DALRD3

Orthologs
for DALRD3

Paralogs
for DALRD3

SNPs/Variants
for DALRD3

Disorders & Mutations
for DALRD3

Medical News
for DALRD3

Publications
for DALRD3

Licensable Technologies
for DALRD3

Services
for DALRD3