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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DAK Gene

protein-coding   GIFtS: 55
GCID: GC11P061100

dihydroxyacetone kinase 2 homolog (S. cerevisiae)

(Previous name: dihydroxyacetone kinase 2 homolog (yeast) )
 Explore 1 disease affiliated with
DAK via our new
 Human Malady Compendium 
Biological research products
for DAK
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Dihydroxyacetone Kinase 2 Homolog (S. Cerevisiae)1 2     DHA Kinase2
NET451 2     Dha Kinase/FMN Cyclase2
DKFZP586B16211     FAD-AMP Lyase Cyclic FMN Forming2
Dihydroxyacetone Kinase 2 Homolog (Yeast)1     FAD-AMP Lyase Cyclizing2
ATP-Dependent Dihydroxyacetone Kinase2     Glycerone Kinase2
Bifunctional ATP-Dependent Dihydroxyacetone Kinase/FAD-AMP Lyase (Cyclizing)2     

External Ids:    HGNC: 245521   Entrez Gene: 260072   Ensembl: ENSG000001494767   UniProtKB: Q3LXA33   

Export aliases for DAK gene to outside databases

Previous GC identifers: GC11P060858 GC11P057428


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DAK:
This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other
kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin
4',5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been identified, but
the full-length nature of only one has been determined. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: DHAK_HUMAN, Q3LXA3
Function: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of
ribonucleoside diphosphate-X compounds among which FAD is the best substrate

Gene Wiki entry for DAK


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DAK gene promoter:
         Tal-1   p53   CUTL1   Nkx2-5   Tal-1beta   E47   STAT3   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDAK promoter sequence
   Search SABiosciences Chromatin IP Primers for DAK

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DAK


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.2   Ensembl cytogenetic band:  11q12.2   HGNC cytogenetic band: 11q12.2

DAK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DAK gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P061100:  view genomic region     (about GC identifiers)

Start:
61,100,654 bp from pter      End:
61,120,767 bp from pter
Size:
20,114 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DHAK_HUMAN, Q3LXA3 (See protein sequence)
Recommended Name: Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)  
Size: 575 amino acids; 58947 Da
Cofactor: Magnesium (By similarity)
Cofactor: Manganese or cobalt; for FAD-AMP lyase activity (By similarity)
Subunit: Homodimer (By similarity)
Secondary accessions: Q53EQ9 Q9BVA7 Q9H895

Explore the universe of human proteins at neXtProt for DAK: NX_Q3LXA3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q3LXA3

  • DAK Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_056348.2  
    ENSEMBL proteins: 
     ENSP00000378360   ENSP00000431844   ENSP00000434405   ENSP00000432539   ENSP00000459382  
    Reactome Protein details: Q3LXA3
    Human Recombinant Protein Products: 
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    Uscn Proteins for DAK

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--


    DAK for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DAK for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR012734 DhaK_ATP
     IPR004006 Dak1
     IPR004007 Dak2

    Graphical View of Domain Structure for InterPro Entry Q3LXA3

    ProtoNet protein and cluster: Q3LXA3

    2 Blocks protein families:
    IPB004006 Dak kinase domain
    IPB004007 Dak phosphatase domain


    UniProtKB/Swiss-Prot: DHAK_HUMAN, Q3LXA3
    Similarity: Belongs to the dihydroxyacetone kinase (DAK) family
    Similarity: Contains 1 DhaK domain
    Similarity: Contains 1 DhaL domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DHAK_HUMAN, Q3LXA3
    Function: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of
    ribonucleoside diphosphate-X compounds among which FAD is the best substrate
    Catalytic activity: ATP + glycerone = ADP + glycerone phosphate
    Catalytic activity: ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate
    Catalytic activity: FAD = AMP + riboflavin cyclic-4',5'-phosphate
    Enzyme regulation: Each activity is inhibited by the substrate(s) of the other
    Biophysicochemical properties: Kinetic parameters: KM=0.5 uM for dihydroxyacetone; KM=11 uM for glyceraldehyde; pH
    dependence: Optimum pH is 6.6;

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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004371glycerone kinase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0034012FAD-AMP lyase (cyclizing) activity IEA--
    GO:0046872metal ion binding IEA--
    GO:0050354triokinase activity IEA--


    DAK for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Immune System
    Immune System1.00
    Innate Immune System0.46
    2RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
    RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways1.00
    RIG-I-like receptor signaling pathway0.52
    3Glycerolipid metabolism
    Glycerolipid metabolism1.00
    4Metabolism
    Metabolic pathways0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for DAK
        RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
    Immune System
    Innate Immune System


    3         Kegg Pathways  (Kegg details for DAK):
        Glycerolipid metabolism
    Metabolic pathways
    RIG-I-like receptor signaling pathway


    DAK for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DAK

    5/10 Interacting proteins for DAK (Q3LXA33) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PIK3R4Q995703I2D: score=4 
    ADCK3Q8NI603I2D: score=1 
    ATICP319393I2D: score=1 
    ATP6V0D1P614213I2D: score=1 
    DLSTP369573I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006071glycerol metabolic process IEA--
    GO:0045087innate immune response TAS--


    DAK for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DAK

    4 HMDB Compounds for DAK    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Dihydroxyacetone1,3-Dihydroxy-2-propanone (see all 21)96-26-4--
    Dihydroxyacetone phosphate1,3-Dihydroxy-2-propanone phosphate (see all 17)57-04-5--
    Search CenterWatch for drugs/clinical trials and news about DAK / DHAK 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DAK gene: 
    NM_015533.3  

    Unigene Cluster for DAK:

    Dihydroxyacetone kinase 2 homolog (S. cerevisiae)
    Hs.6278  [show with all ESTs]
    Unigene Representative Sequence: NM_015533
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000394900(uc001nre.3) ENST00000531820 ENST00000530456 ENST00000532173
    ENST00000530057 ENST00000525170 ENST00000529121 ENST00000529620 ENST00000533393
    ENST00000524968 ENST00000529479(uc009ynm.1) ENST00000529092 ENST00000533853
    ENST00000524953 ENST00000534134 ENST00000534370 ENST00000528061 ENST00000534084


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    hsa-miR-3934 hsa-miR-3650 hsa-miR-1237 hsa-miR-513a-5p hsa-miR-29a* hsa-miR-4294
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    Inhib. RNA
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    Additional cDNA sequence: 

    AK023915.1 AK094516.1 AK223580.1 AK308553.1 AL110260.1 BC001341.1 BC120929.1 DQ138290.1 
    DQ344550.1 

    24/31 DOTS entries (see all 31):

    DT.100887611  DT.95291946  DT.100794636  DT.100692202  DT.100794639  DT.409045  DT.100794632  DT.100794637 
    DT.95209797  DT.120694308  DT.91756060  DT.95306474  DT.100794635  DT.91770183  DT.120694277  DT.120694245 
    DT.91905992  DT.97848309  DT.100030287  DT.100794634  DT.100794640  DT.120694197  DT.120694199  DT.120694208 

    24/279 AceView cDNA sequences (see all 279):

    BQ063430 BE280843 BM834565 CF530076 BQ691975 BQ056528 BP359130 BE294399 
    AI367550 BP350046 BQ057535 BU542946 BM820361 BQ056098 BM820134 BQ006950 
    BQ056458 AA354853 BG470378 BF057597 BQ061010 CR593561 BM856323 BQ687295 

    GeneLoc Exon Structure

    5/15 Alternative Splicing Database (ASD) splice patterns (SP) for DAK (see all 15)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ·
    SP1:                          -     -     -     -     -     -           -     -                                                           -           -     -   
    SP2:                                      -     -     -     -           -     -                                                           -                     
    SP3:                          -     -     -     -     -     -           -     -                       -     -     -     -     -     -     -     -     -     -   
    SP4:                          -           -     -     -     -           -     -                                                                                 
    SP5:                          -     -     -     -     -     -                 -                                                                                 

    ExUns: 11c ^ 12 ^ 13a · 13b · 13c ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21a · 21b
    SP1:                    -     -                                                               
    SP2:                                                                                          
    SP3:  -     -     -     -     -     -     -     -     -     -                                 
    SP4:                                                                                          
    SP5:                                                                                          


    ECgene alternative splicing isoforms for DAK

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DAK expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAAGCAAGAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See DAK Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DAK

    SOURCE GeneReport for Unigene cluster: Hs.6278

    UniProtKB/Swiss-Prot: DHAK_HUMAN, Q3LXA3
    Tissue specificity: Detected in erythrocytes (at protein level)

        SABiosciences Expression via Pathway-Focused PCR Array including DAK: 
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for DAK gene from 10/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dak1 , 5 dihydroxyacetone kinase 2 homolog (yeast)1, 5 83.59(n)1
    85.39(a)1
      19 (6.60 cM)5
    2259131  NM_145496.11  NP_663471.11 
     105922005 
    chicken
    (Gallus gallus)
    Aves DAK1 dihydroxyacetone kinase 2 homolog (S. cerevisiae) 72.05(n)
    75.44(a)
      426629  XM_424258.3  XP_424258.3 
    lizard
    (Anolis carolinensis)
    Reptilia DAK6
    --
    70(a)
    1 ↔ 1
    GL343235.1(790286-811710)
    zebrafish
    (Danio rerio)
    Actinopterygii dak1 dihydroxyacetone kinase 2 homolog (S. cerevisiae) 60.6(n)
    56.22(a)
      793926  NM_001076630.1  NP_001070098.1 
    honey bee
    (Apis mellifera)
    Insecta --
    --
    32(a)
    1 ↔ 1
    GroupUn.892(13134-19167)
    worm
    (Caenorhabditis elegans)
    Secernentea W02H5.81 Protein W02H5.8 49.21(n)
    43.43(a)
      178730  NM_071323.3  NP_503724.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DAK21 Dak2p 44.95(n)
    38.45(a)
      850491   NP_116602.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G177701 Dihydroxyacetone kinase 48.73(n)
    43.34(a)
      821045  NM_112658.3  NP_188404.1 
    rice
    (Oryza sativa)
    Liliopsida Os.460882 Oryza sativa (japonica cultivar-group) cDNA clone0 more 75.74(n)    AK119254.1 
    E. coli
    (Escherichia coli)
    Gamma proteobacteria dhaK6
    dihydroxyacetone kinase, PTS-dependent, dihydroxya...
    40(a)
    1 ↔ 1
    Chromosome(1248991-1250061) b1200


    ENSEMBL Gene Tree for DAK (if available)
    TreeFam Gene Tree for DAK (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/317 NCBI SNPs in DAK are shown (see all 317    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs127930991,2
    C,A--61102748(+) CTTTTC/TCTTCA 1 -- int1 trp30--------
    rs1829301641,2
    --61102762(+) GCATTA/TTAAGG 1 -- int10--------
    rs1851864211,2
    --61102772(+) GCAAAG/TTAAGG 1 -- int10--------
    rs560466391,2
    C,--61102882(+) ATAGCA/GCTGGT 1 -- int12Minor allele frequency- G:0.13WA 120
    rs1450724391,2
    --61102897(+) AAACCC/TTCTTC 1 -- int10--------
    rs1399902231,2
    --61103205(+) GCCTCA/TGTTTC 1 -- int10--------
    rs1902901651,2
    --61103301(+) TGCTCC/TTTTTG 1 -- int10--------
    rs1825172621,2
    --61103323(+) GTGCAA/GTGGCG 1 -- int10--------
    rs1871752511,2
    --61103480(+) AGGCTA/GGTCTC 1 -- int10--------
    rs1126300961,2
    --61103486(+) GTCTCG/AAACTC 1 -- int11Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for DAK (61100654 - 61120767 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for DAK
         2 CNVs: 4748 101234
         5 Indels: 44919 43039 24773 39843 61156

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DAK for disorders           About GeneDecksing

    1 disease for DAK:    About MalaCards
    dyslexia

    1 disease from the University of Copenhagen DISEASES database for DAK:
    Dyslexia
    Human Genome Epidemiology (HuGE) Navigator: DAK (3 documents)

    Export disorders for DAK gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DAK gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with DAK)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of human and rat FAD-AMP lyase (cyclic FMN forming) as ATP-dependent dihydroxyacetone kinases. (PubMed id 16289032)1, 2, 9 Cabezas A.... Cameselle J.C. (2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    6. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26007 HGNC: 24552 AceView: DKFZP586B1621 Ensembl:ENSG00000149476 euGenes: HUgn26007
    ECgene: DAK Kegg: 26007 H-InvDB: DAK

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DAK Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DAK gene:
    Search GeneIP for patents involving DAK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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