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DAK Gene

protein-coding GIFtS: 56

GC11P060858

dihydroxyacetone kinase 2 homolog (S. cerevisiae)
(Previous name: dihydroxyacetone kinase 2 homolog (yeast) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DKFZP586B1621 ^¹
DKFZp586B1621 ^²
MGC5621 ^²

Descriptions
ATP-dependent dihydroxyacetone kinase ^²
DHA kinase ^²
Dha kinase/FMN cyclase ^²
FAD-AMP lyase cyclic FMN forming ^²
FAD-AMP lyase cyclizing ^²
dihydroxyacetone kinase 2 ^²
dihydroxyacetone kinase 2 homolog (S. cerevisiae) ^²
dihydroxyacetone kinase 2 homolog (yeast) ^¹
glycerone kinase ^²

External Ids
HGNC: 24552¹
Entrez Gene: 26007²
UniProtKB: Q3LXA3³
Ensembl: ENSG00000149476⁷

Search outside databases for aliases for DAK gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for DAK:

This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure

distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also

catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclin FMN) from FAD. Several

alternatively spliced transcript variants have been identified, but the full-length nature of only

one has been determined. [provided by RefSeq]

UniProtKB/Swiss-Prot: DHAK_HUMAN, Q3LXA3

Function: Catalyzes both the phosphorylation of dihydroxyacetone and the splitting of

ribonucleoside diphosphate-X compounds among which FAD is the best substrate

Gene Wiki entry for DAK

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DAK gene

Entrez Gene cytogenetic band: 11q12.2 Ensembl cytogenetic band: 11q12.2 HGNC cytogenetic band: 11q12.2

DAK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P060858: (about GC identifiers)

Start:	60,857,230 bp from pter
End:	60,872,807 bp from pter
Size:	15,578 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000011.8 NT_033903.7

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: DHAK_HUMAN, Q3LXA3 (See protein sequence)

Recommended Name: Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)

Size: 575 amino acids; 58977 Da

Cofactor: Magnesium (By similarity)

Cofactor: Manganese or cobalt; for FAD-AMP lyase activity (By similarity)

Subunit: Homodimer (By similarity)

Secondary accessions: Q53EQ9 Q9BVA7 Q9H895

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_056348.2

ENSEMBL proteins:

ENSP00000378360 ENSP00000310493

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (DAK)
	Human Recombinant Proteins from Abnova (DAK)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

Antibodies for DAK:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for DAK
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (DAK), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (DAK)
	Novus Biologicals Antibodies for DAK

Assays for DAK:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q3LXA3

ProtoNet protein and cluster: Q3LXA3

2 Blocks protein families:

IPB004006 Dak kinase domain

IPB004007 Dak phosphatase domain

UniProtKB/Swiss-Prot: DHAK_HUMAN, Q3LXA3

Similarity: Belongs to the dihydroxyacetone kinase (DAK) family

Similarity: Contains 1 DAK1 (dihydroxyacetone kinase subunit 1) domain

Similarity: Contains 1 DAK2 (dihydroxyacetone kinase subunit 2) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAK)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DAK)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_015533

Applied Biosystems Silencer® siRNAs for DAK

Sigma-Aldrich siRNA and siRNA Panels for DAK

Sigma-Aldrich shRNA Panels and shRNA for DAK

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for DAK
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_015533
Myc/DDK tagged cDNA clone in CMV expression vector: NM_015533
untagged cDNA clones in CMV expression vector (see all 2): NM_015533

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_015533

UniProtKB/Swiss-Prot: DHAK_HUMAN, Q3LXA3

Function: Catalyzes both the phosphorylation of dihydroxyacetone and the splitting of

ribonucleoside diphosphate-X compounds among which FAD is the best substrate

Catalytic activity: ATP + glycerone = ADP + glycerone phosphate

Catalytic activity: FAD = AMP + riboflavin cyclic-4',5'-phosphate

Enzyme regulation: Each activity is inhibited by the substrate(s) of the other

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0004371	glycerone kinase activity	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0016740	transferase activity	IEA	--
GO:0016829	lyase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/20 Interacting proteins for DAK (ENSP00000310493³) via UniProtKB, MINT, and/or STRING (see all 20 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GPD1	ENSP00000301149³	STRING (score=.928)
GPD2	ENSP00000308610³	STRING (score=.874)
TPI1	ENSP00000371705³	STRING (score=.844)
PGK1	ENSP00000362413³	STRING (score=.82)
PGK2	ENSP00000305995³	STRING (score=.818)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006071	glycerol metabolic process	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for DAK

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAK)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DAK)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_015533

Sigma-Aldrich siRNA and siRNA Panels for DAK

Sigma-Aldrich shRNA Panels and shRNA for DAK

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_015533

REFSEQ mRNAs for DAK gene:

NM_015533.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_015533

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_015533
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_015533
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_015533

Additional cDNA sequence:

AK023915.1 AK094516.1 AK223580.1 AK308553.1 AL110260.1 BC001341.1 BC120929.1 CR593561.1

DQ138290.1 DQ344550.1

24/31 DOTS entries (see all 31 ):

DT.100887611 DT.95291946 DT.100794636 DT.100692202 DT.100794639 DT.409045 DT.100794632 DT.100794637

DT.95209797 DT.120694308 DT.91756060 DT.95306474 DT.100794635 DT.91770183 DT.120694277 DT.120694245

DT.91905992 DT.97848309 DT.100030287 DT.100794634 DT.100794640 DT.120694197 DT.120694199 DT.120694208

24/279 AceView cDNA sequences (see all 279 ):

BM856323 CR593561 NM_015533 BM834565 AA354853 BQ056458 BQ650326 BQ056098

BQ057535 BP350046 BM707939 BG120718 BQ928939 BM820134 BM561417 BG819948

BM820361 BF868362 CF530076 BQ063430 CD358913 BQ061010 BU542946 BQ054864

highest scoring ESTs for DAK:

AA809956 AA962405 AA995380 AI589299 AI685406 AI889175 AK023915 AL110260 AL530013 AL581165

Unigene Cluster for DAK:

Dihydroxyacetone kinase 2 homolog (S. cerevisiae)

Hs.6278 [show with all ESTs]

Unigene Representative Sequence: NM_015533

GeneLoc Exon Structure

5/15 Alternative Splicing Database (ASD) splice patterns (SP) for DAK (see all 15 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	·	2c	·	2d	^	3a	·	3b	·	3c	^	4	^	5	^	6a	·	6b	·	6c	^	7	^	8a	·	8b	·	8c	^	9a	·	9b	^	10a	·	10b	^	11a	·	11b	·
SP1:									-		-		-		-		-		-				-		-																				-				-		-
SP2:													-		-		-		-				-		-																				-
SP3:									-		-		-		-		-		-				-		-								-		-		-		-		-		-		-		-		-		-
SP4:									-				-		-		-		-				-		-
SP5:									-		-		-		-		-		-						-

ExUns:	11c	^	12	^	13a	·	13b	·	13c	^	14	^	15	^	16	^	17	^	18a	·	18b	^	19	^	20	^	21a	·	21b
SP1:							-		-
SP2:
SP3:	-		-		-		-		-		-		-		-		-		-
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for DAK

2 Ensembl transcripts including schematic representations:

ENST00000394900 ENST00000311463

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

DAK expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DAK

¹ / ² / ³

7 probe-sets matching DAK gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
71827_at²^{, 3}	U95-E	1	1.00	1.00	0.92	0.84	AI565170	0.60	1.00	0.82	1
75777_at²^{, 3}	U95-E	1	1.00	1.00	0.94	1.03	AA676980	0.40	1.00	0.76	1
46570_at²^{, 3}	U95-B	2	1.00	0.97	0.99	1.13	AI889175	0.80	1.00	0.91	1
244627_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BE300882	0.40	1.00	0.76	1
218688_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_015533	0.60	1.00	0.82	1
244627_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
218688_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks DAK for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GAAGCAAGAA

SOURCE GeneReport for Unigene cluster: Hs.6278

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DAK gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DAK¹	--	dihydroxyacetone kinase 2 homolog (S. cerevisiae)	89.62(n) 91.48(a)	483800 XM_540921.2 XP_540921.2
chimpanzee (Pan troglodytes)	DAK¹	--	dihydroxyacetone kinase 2 homolog (S. cerevisiae)	99.42(n) 100(a)	466626 XM_001147724.1 XP_001147724.1
cow (Bos taurus)	DAK¹	--	dihydroxyacetone kinase 2 homolog (S. cerevisiae)	89.51(n) 93.21(a)	512373 NM_001024524.1 NP_001019695.1
rat (Rattus norvegicus)	Dak¹	--	dihydroxyacetone kinase 2 homolog (S. cerevisiae)	83.83(n) 85.91(a)	361730 NM_001039031.1 NP_001034120.1
mouse (Mus musculus)	Dak^{1, 5}	19⁵	dihydroxyacetone kinase 2 homolog (yeast)^{1, 5}	83.59(n)¹ 85.39(a)¹	225913¹ NM_145496.1¹ NP_663471.1¹ AK138956⁵ AK171418⁵ (see all 6)

About this table Species with no ortholog for DAK

ENSEMBL Gene Tree for DAK

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/84 NCBI SNPs in DAK are shown (see all 84 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 77)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2260655^1,2	A,C,F,H	60865550(+)	`TGGTCA/GCCAAG`	1	A/T	mis¹ ese³		10	EA EU WA NA	2408
	rs3972757^1,2	C,F,H	60871192(+)	`TTTCTC/TAGCAT`	1	--	ut3¹		7	EU EA WA NA	562
	rs12292734^1,2	F,H	60872064(+)	`AAATTT/CGGCTG`	1	--	ut3¹		4	EU EA WA	408
	rs35723406^1,2	C,F	60867922(+)	`TGCAGC/GAGCCT`	1	A/G	mis¹		5	NA EU EA WA	458
	rs2513329^1,2	A,C,F,H	60863468(+)	`GGCACC/GGTGCT`	1	T/T	syn¹ ese³		8	EU EA WA NA	630
	rs2305465^1,2	A,C,F,H	60869378(+)	`TCTGTT/CCTGCT`	1	V/V	syn¹		6	EA EU WA NA	1994
--	rs11826324^1,2	C,F	60867421(+)	`GCCCTG/CGTGGG`	1	L/L	syn¹ ese³		1	NA	60
	rs4939514^1,2	A,C,F,H	60866745(+)	`TCCTAC/AACCTC`	1	--	int¹		4	EU EA WA	412
	rs3741268^1,2	A,C,F,H	60866251(+)	`CGGCTA/GTTCAA`	1	--	int¹		4	EU EA WA	420
	rs2512809^1,2	A,C,F,H	60863101(-)	`TGGAAA/GGAGTG`	1	--	int¹		5	EA EU WA	1912

About this table

HapMap Linkage Disequilibrium images for DAK (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10 PubMed articles for DAK gene:

Identification of human and rat FAD-AMP lyase (cyclic FMN forming) as ATP-dependent dihydroxyacetone kinases. (PubMed id 16289032)^{1, 3, 4} Cabezas A....Cameselle J.C. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Negative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinase. (PubMed id 17600090)³ Diao F....Shu H.B. (2007)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)³ Kimura K.... Sugano S. (2006)
A comprehensive update of the sequence and structure classification of kinases. (PubMed id 15771780)³ Cheek S....Grishin N.V. (2005)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
Construction and characterization of a full length-enriched and a 5'- end-enriched cDNA library. (PubMed id 9373149)³ Suzuki Y.... Sugano S. (1997)
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)³ Maruyama K. and Sugano S. (1994)
EDD, a novel phosphotransferase domain common to mannose transporter EIIA, dihydroxyacetone kinase, and DegV. (PubMed id 15632288)¹ Kinch L.N....Grishin N.V. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 26007	HGNC: 24552	AceView: DKFZP586B1621	Ensembl:ENSG00000149476	euGenes: HUgn26007
ECgene: DAK	H-InvDB: DAK

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for DAK
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for DAK:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DAK-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DAK		Antibodies for DAK
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DAK		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
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DAK Gene

protein-coding GIFtS: 56

Aliases &
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Genomic Location
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Proteins
for DAK

Protein Domains/
Families
for DAK

Gene Function
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Pathways & Interactions
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Drugs & Compounds
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Transcripts
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Expression
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Disorders & Mutations
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Medical News
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Publications
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Genome Databases showing DAK

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DAK Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor DAK

Summariesfor DAK

Genomic Locationfor DAK

Proteinsfor DAK

Protein Domains/Familiesfor DAK

Gene Functionfor DAK

Pathways & Interactionsfor DAK

Drugs & Compoundsfor DAK

Transcriptsfor DAK

Expression for DAK

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Disorders & Mutationsfor DAK

Medical Newsfor DAK

Publicationsfor DAK

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Genome Databases showing DAK

Other Databases showing DAK

Specialized Databases showing DAK

Licensable Technologiesfor DAK

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DAK

Summaries
for DAK

Genomic Location
for DAK

Proteins
for DAK

Protein Domains/
Families
for DAK

Gene Function
for DAK

Pathways & Interactions
for DAK

Drugs & Compounds
for DAK

Transcripts
for DAK

Expression
for DAK

Orthologs
for DAK

Paralogs
for DAK

SNPs/Variants
for DAK

Disorders & Mutations
for DAK

Medical News
for DAK

Publications
for DAK

Licensable Technologies
for DAK

Services
for DAK