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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DAGLA Gene

protein-coding   GIFtS: 51
GCID: GC11P061447

diacylglycerol lipase, alpha

(Previous name: chromosome 11 open reading frame 11 )
(Previous symbol: C11orf11)
 Explore 4 diseases affiliated with
DAGLA via our new
 Human Malady Compendium 
Biological research products
for DAGLA
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Diacylglycerol Lipase, Alpha1 2     DGL-Alpha1
C11orf111 2 3     Chromosome 11 Open Reading Frame 111
NSDDR1 2 3     DAGL(ALPHA)2
DAGLALPHA1 2     Sn1-Specific Diacylglycerol Lipase Alpha2
KIAA06591 3     EC 3.1.1.-3
Neural Stem Cell-Derived Dendrite Regulator2 3     

External Ids:    HGNC: 11651   Entrez Gene: 7472   Ensembl: ENSG000001347807   OMIM: 6140155   UniProtKB: Q9Y4D23   

Export aliases for DAGLA gene to outside databases

Previous GC identifers: GC11P061205 GC11P057776


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for DAGLA:
This gene encodes a diacylglycerol lipase. The encoded enzyme is involved in the biosynthesis of the endocannabinoid
2-arachidonoyl-glycerol.(provided by RefSeq, Nov 2010)

UniProtKB/Swiss-Prot: DGLA_HUMAN, Q9Y4D2
Function: Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant
endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at
mature synapses




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DAGLA gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   AP-2gamma   E2F   E2F-1   AP-2beta   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDAGLA promoter sequence
   Search SABiosciences Chromatin IP Primers for DAGLA

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DAGLA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.2   Ensembl cytogenetic band:  11q12.2   HGNC cytogenetic band: 11q12.3

DAGLA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DAGLA gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P061447:  view genomic region     (about GC identifiers)

Start:
61,447,905 bp from pter      End:
61,514,473 bp from pter
Size:
66,569 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: DGLA_HUMAN, Q9Y4D2 (See protein sequence)
Recommended Name: Sn1-specific diacylglycerol lipase alpha  
Size: 1042 amino acids; 114952 Da
Cofactor: Calcium
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=BAA31634.2; Type=Erroneous initiation;
Secondary accessions: A7E233 Q6WQJ0

Explore the universe of human proteins at neXtProt for DAGLA: NX_Q9Y4D2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y4D2

  • DAGLA Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006124.1  
    ENSEMBL proteins: 
     ENSP00000257215   ENSP00000440264  
    Reactome Protein details: Q9Y4D2
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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--


    DAGLA for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    DAGLA for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR002921 Lipase_3

    Graphical View of Domain Structure for InterPro Entry Q9Y4D2

    ProtoNet protein and cluster: Q9Y4D2

    UniProtKB/Swiss-Prot: DGLA_HUMAN, Q9Y4D2
    Similarity: Belongs to the AB hydrolase superfamily. Lipase family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: DGLA_HUMAN, Q9Y4D2
    Function: Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant
    endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at
    mature synapses
    Enzyme regulation: Inhibited by p-hydroxy-mercuri-benzoate and HgCl(2), but not to PMSF. Also inhibited by RHC80267, a
    drug that blocks 2-AG formation
    Biophysicochemical properties: Kinetic parameters: KM=154.7 uM for diacylglycerol; Vmax=33.3 nmol/min/mg enzyme; pH
    dependence: Optimum pH is 7.0;

    Enzyme Number (IUBMB): EC 3.1.1.-1

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    SwitchGear 3'UTR luciferase reporter plasmidDAGLA 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004806triglyceride lipase activity IEA--
    GO:0046872metal ion binding IEA--


    DAGLA for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for DAGLA:
     Increased cell number in G2M,   Upregulation of Wnt/beta-caten 

    Animal Models:
         Mouse knock-out Daglatm1.1Kano for DAGLA
         4 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Dagla):
     cellular  growth/size  homeostasis/metabolism  nervous system 

    DAGLA for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Signaling by GPCR
    Signaling by GPCR1.00
    Signal Transduction0.56
    GPCR downstream signaling0.89
    2Platelet activation, signaling and aggregation
    Platelet activation, signaling and aggregation1.00
    Hemostasis0.43
    3G alpha (q) signalling events
    G alpha (q) signalling events1.00
    Gastrin-CREB signalling pathway via PKC and MAPK0.90
    4Development_Dopamine D2 receptor transactivation of EGFR
    Development_Alpha-2 adrenergic receptor activation of ERK0.66
    Development Alpha-2 adrenergic receptor activation of ERK0.66
    5Effects of PIP2 hydrolysis
    Effects of PIP2 hydrolysis1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for DAGLA
        Development Alpha-2 adrenergic receptor activation of ERK


    1 GeneGo (Thomson Reuters) Pathway for DAGLA
        Development Alpha-2 adrenergic receptor activation of ERK

    1 BioSystems Pathway for DAGLA 
        N-cadherin signaling events

    5/9        Reactome Pathways for DAGLA (see all 9)
        GPCR downstream signaling
    Hemostasis
    Gastrin-CREB signalling pathway via PKC and MAPK
    Signaling by GPCR
    Arachidonate production from DAG



    DAGLA for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DAGLA

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for DAGLA (Q9Y4D23 ENSP000002572154) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GIPC1O149083I2D: score=1 
    MGLLENSP000002650524STRING: ENSP00000265052
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007596blood coagulation TAS--
    GO:0008219cell death IEA--
    GO:0016042lipid catabolic process IEA--
    GO:0030168platelet activation TAS--


    DAGLA for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    EMD Millipore small molecules for DAGLA:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DAGLA

    10/844 HMDB Compounds for DAGLA (see all 844)    About this table
    CompoundSynonyms CAS #PubMed Ids
    DG(16:0e/18:0/0:0)2-Octadecanoyl-1-hexadecyl-sn-glycerol (see all 2)--12486725
    CalciumCa (see all 2)7440-70-2--
    DG(14:0/14:0/0:0)DAG(14:0/14:0) (see all 9)----
    DG(14:0/14:1(9Z)/0:0)DAG(14:0/14:1) (see all 15)----
    DG(14:0/15:0/0:0)Diacylglycerol(29:0) (see all 9)----
    DG(14:0/16:0/0:0)DAG(30:0) (see all 9)----
    DG(14:0/16:1(9Z)/0:0)DG(30:1) (see all 15)----
    DG(14:0/18:0/0:0)DG(14:0/18:0) (see all 9)----
    DG(14:0/18:1(11Z)/0:0)Diacylglycerol (see all 15)----
    DG(14:0/18:1(9Z)/0:0)1-myristoyl-2-oleoyl-sn-glycerol (see all 15)----
    Search CenterWatch for drugs/clinical trials and news about DAGLA / DGLA 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DAGLA gene: 
    NM_006133.2  

    Unigene Cluster for DAGLA:

    Diacylglycerol lipase, alpha
    Hs.241564  [show with all ESTs]
    Unigene Representative Sequence: BC150195
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000257215(uc001nsa.3) ENST00000540717

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    hsa-miR-323-3p hsa-miR-3607-3p hsa-miR-300 hsa-miR-1914* hsa-miR-485-3p hsa-miR-30d hsa-miR-4267 hsa-miR-30a
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    Inhib. RNA
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    Additional cDNA sequence: 

    AB014559.2 AY275377.1 BC150176.1 BC150195.1 BC152453.1 

    2 DOTS entries:

    DT.105877  DT.92419455 

    24/40 AceView cDNA sequences (see all 40):

    BM126486 AI140579 BM068819 BI964010 CR596071 AY275377 AI216160 CK904653 
    BI964152 NM_006133 T16247 BI918354 BE735837 BM763121 BG748842 AB014559 
    BE615414 BM054786 BE531065 BI752614 BE907563 BX645187 BG764500 BE531188 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DAGLA expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CACTCTCTTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See DAGLA Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DAGLA

    SOURCE GeneReport for Unigene cluster: Hs.241564

    UniProtKB/Swiss-Prot: DGLA_HUMAN, Q9Y4D2
    Tissue specificity: Highly expressed in brain and pancreas

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DAGLA

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for DAGLA gene from 8/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves DAGLA1 diacylglycerol lipase, alpha 79.79(n)
    89.31(a)
      426017  XM_423696.3  XP_423696.3 
    lizard
    (Anolis carolinensis)
    Reptilia DAGLA6
    --
    89(a)
    1 ↔ 1
    GL343235.1(1582575-1640139)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ640573.12   -- 73.13(n)    BJ640573.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dagla1 diacylglycerol lipase, alpha 68.16(n)
    72.97(a)
      569398  XM_692781.4  XP_697873.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta inaE1 inactivation no afterpotential E 48.81(n)
    38.89(a)
      32343  NM_001144723.1  NP_001138195.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F42G9.66
    --
    25(a)
    possible ortholog
    III(778237-783299)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G424506
    AT4G160706
    (see all 3)
    lipase class 3 family protein
    (see all 3)
    14(a)
    12(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    2(17672253-17675019)
    4(9096689-9100983)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 6)
    lipase, putative, expressed
    (see all 6)
    17(a)
    15(a)
    (see all 6)
    many ↔ many
    many ↔ many
    (see all 6)
    12(22496653-22501413)
    9(22810710-22813586)


    ENSEMBL Gene Tree for DAGLA (if available)
    TreeFam Gene Tree for DAGLA (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DAGLA gene
    DAGLB2  
    1 SIMAP similar gene for DAGLA using alignment to 2 protein entries:     DGLA_HUMAN (see all proteins):
    DAGLB

    DAGLA for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/965 NCBI SNPs in DAGLA are shown (see all 965    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1881809431,2
    --61445945(+) CTCTGC/TCTCCC 1 -- us2k10--------
    rs1155313611,2
    F,--61446038(+) CTTTGG/ATAGAG 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1807083111,2
    --61446153(+) CCCCTA/GGCCGA 1 -- us2k10--------
    rs1850470341,2
    --61446161(+) CGACAA/GTCTTT 1 -- us2k10--------
    rs1902960531,2
    --61446217(+) TCAACG/TGGGAA 1 -- us2k10--------
    rs1452878721,2
    --61446283(+) TGACCA/GTGGCC 1 -- us2k10--------
    rs49633041,2
    C,F,A,--61446352(+) ATCCAG/ATCTGG 1 -- us2k110Minor allele frequency- A:0.45NA WA CSA EA 372
    rs79315631,2
    C,F,A,H,--61446425(+) AGTTGT/GCCCTT 1 -- us2k124Minor allele frequency- G:0.47NS EA NA WA 2762
    rs1491619961,2
    --61446483(+) TCCTCC/TTTGAA 1 -- us2k10--------
    rs79423871,2
    C,F,--61446501(+) AGGTGC/ACCCAC 1 -- us2k11Minor allele frequency- A:0.11WA 118

    HapMap Linkage Disequilibrium report for DAGLA (61447905 - 61514473 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DAGLA: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    DAGLA for disorders           About GeneDecksing

    OMIM gene information: 614015    OMIM disorders: --

    UniProtKB/Swiss-Prot: DGLA_HUMAN, Q9Y4D2
  • Defects in DAGLA may be a cause of spinocerebellar ataxia type 20 (SCA20) [MIM:608687]. Spinocerebellar ataxia
  • is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination
    of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with
    variable involvement of the brainstem and spinal cord. SCA20 is an autosomal dominant, adult-onset form characterized
    by dysarthria due to spasmodic dysphonia followed by slowly progressive ataxia. Note=A copy number variation
    consisting of a 260-kb duplication at chromosome 11q12.2-12.3 is responsible for SCA20. The critical gene within the
    duplicated segment may be DAGLA

    4 diseases for DAGLA:    About MalaCards
    spasmodic dysphonia    spinocerebellar ataxia type 20    spinocerebellar ataxia    ataxia


    Export disorders for DAGLA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DAGLA gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with DAGLA)
        Utopia: connect your pdf to the dynamic
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    1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (1998)
    2. A duplication at chromosome 11q12.2-11q12.3 is associ ated with spinocerebellar ataxia type 20. (PubMed id 18801880)1, 2 Knight M.A....Singleton A.B. (2008)
    3. Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. (PubMed id 16051747)1, 2 Jung K.-M.... Piomelli D. (2005)
    4. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. (PubMed id 14610053)1, 2 Bisogno T.... Doherty P. (2003)
    5. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
    6. Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. (PubMed id 22610502)1 Kennedy R.B....Poland G.A. (2012)
    7. Genetic loci associated with plasma phospholipid n-3 f atty acids: a meta-analysis of genome-wide association studies from the CHARGE C onsortium. (PubMed id 21829377)1 Lemaitre R.N....Steffen L.M. (2011)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Insights into the bile acid transportation system: the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures. (PubMed id 12486725)6 Kurz M....Kramer W. (2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 747 HGNC: 1165 AceView: C11orf11 Ensembl:ENSG00000134780 euGenes: HUgn747
    ECgene: DAGLA H-InvDB: DAGLA

    (According to HUGE)
    About This Section
    HUGE: KIAA0659

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DAGLA Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DAGLA gene:
    Search GeneIP for patents involving DAGLA

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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