Aliases for DAD1 Gene
Aliases for DAD1 Gene
- Defender Against Cell Death 1 2 3 4 5
- Oligosaccharyltransferase Subunit 2 (Non-Catalytic) 2 3
- Oligosaccharyl Transferase Subunit DAD1 3 4
- DAD-1 3 4
- Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit DAD1 3
- Oligosaccharyltransferase 2 Homolog (S. Cerevisiae) 2
- Oligosaccharyltransferase 2 Homolog 3
- EC 2.4.1.119 61
- OST2 3
External Ids for DAD1 Gene
- HGNC: 2664
- Entrez Gene: 1603
- Ensembl: ENSG00000129562
- OMIM: 600243
- UniProtKB: P61803
Previous GeneCards Identifiers for DAD1 Gene
- GC14M020406
- GC14M016821
- GC14M021023
- GC14M022103
- GC14M023033
- GC14M003152
Summaries for DAD1 Gene
-
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008]
GeneCards Summary for DAD1 Gene
DAD1 (Defender Against Cell Death 1) is a Protein Coding gene. Among its related pathways are Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF) and Protein processing in endoplasmic reticulum. GO annotations related to this gene include dolichyl-diphosphooligosaccharide-protein glycotransferase activity and oligosaccharyl transferase activity.
UniProtKB/Swiss-Prot for DAD1 Gene
-
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for the assembly of both SST3A- and SS3B-containing OST complexes. Required for efficient N-glycosylation. Loss of the DAD1 protein triggers apoptosis.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DAD1 Gene
Genomics for DAD1 Gene
Regulatory Elements for DAD1 Gene
Enhancers for DAD1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around DAD1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for DAD1 Gene
- Chromosome:
- 14
- Start:
- 22,564,905 bp from pter
- End:
- 22,589,269 bp from pter
- Size:
- 24,365 bases
- Orientation:
- Minus strand
Genomic View for DAD1 Gene
Genes around DAD1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q11.2 by Ensembl
- 14q11.2 by Entrez Gene
- 14q11.2 by HGNC
DAD1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DAD1 Gene
Proteins for DAD1 Gene
-
Protein details for DAD1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P61803-DAD1_HUMAN
- Recommended name:
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
- Protein Accession:
- P61803
- D3DS25
- O08552
- O70364
- P46966
- P46968
- Q6FGA3
- Q96GB7
Protein attributes for DAD1 Gene
- Size:
- 113 amino acids
- Molecular mass:
- 12497 Da
- Quaternary structure:
-
- Component of the oligosaccharyltransferase (OST) complex. OST exists in two different complex forms which contain common core subunits RPN1, RPN2, OST48, OST4, DAD1 and TMEM258, either STT3A or STT3B as catalytic subunits, and form-specific accessory subunits. OST can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes.
Protein Expression for DAD1 Gene
Selected DME Specific Peptides for DAD1 Gene
- P61803:
-
- YCLLVGTFPFNSFLSGFIS
- SVISRFLEEYLS
- FQGISPERAFADFLFA
- LTGALQFGYCL
Post-translational modifications for DAD1 Gene
Other Protein References for DAD1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
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- antibodies-online Antibodies for DAD1: See all 78
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-
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Protein Products
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Assay Products
- antibodies-online Kits for DAD1: See all 6
Domains & Families for DAD1 Gene
Gene Families for DAD1 Gene
Suggested Antigen Peptide Sequences for DAD1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P61803- Family:
-
- Belongs to the DAD/OST2 family.
Function for DAD1 Gene
Molecular function for DAD1 Gene
- GENATLAS Biochemistry:
- defender against apoptosis
- UniProtKB/Swiss-Prot Function:
- Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for the assembly of both SST3A- and SS3B-containing OST complexes. Required for efficient N-glycosylation. Loss of the DAD1 protein triggers apoptosis.
Enzyme Numbers (IUBMB) for DAD1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004576 | contributes_to oligosaccharyl transferase activity | IBA,ISS | -- |
| GO:0004579 | contributes_to dolichyl-diphosphooligosaccharide-protein glycotransferase activity | IC,IEA | 15835887 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016757 | transferase activity, transferring glycosyl groups | IEA | -- |
Phenotypes for DAD1 Gene
- MGI mutant phenotypes for DAD1:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for DAD1:
-
- Increased vaccinia virus (VACV) infection
- Negative genetic interaction between MUS81-/- and MUS81+/+
- Decreased viability in esophageal squamous lineage
- Decreased IL-8 secretion
- Increased transcriptional activity
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Increased cell number in S
- Synthetic lethal with vaccinia virus (VACV) infection
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for DAD1 gene
-
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- Search ViGene Biosciences for DAD1
CRISPR Products
-
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-
Santa Cruz Biotechnology (SCBT) CRISPR for DAD1
- GenScript: Design CRISPR guide RNA sequences for DAD1
miRNA for DAD1 Gene
- miRTarBase miRNAs that target DAD1
-
- hsa-mir-621 (MIRT137897)
- hsa-mir-382-5p (MIRT440851)
- hsa-mir-19b-3p (MIRT552147)
- hsa-mir-19a-3p (MIRT552148)
- hsa-mir-3185 (MIRT552149)
- hsa-mir-4716-5p (MIRT552150)
- hsa-mir-4762-5p (MIRT552151)
- hsa-mir-454-3p (MIRT552152)
- hsa-mir-4295 (MIRT552153)
- hsa-mir-3666 (MIRT552154)
- hsa-mir-301b-3p (MIRT552155)
- hsa-mir-301a-3p (MIRT552156)
- hsa-mir-130b-3p (MIRT552157)
- hsa-mir-130a-3p (MIRT552158)
- hsa-mir-4274 (MIRT552159)
- hsa-mir-4519 (MIRT552160)
- hsa-mir-520e (MIRT552161)
- hsa-mir-520d-3p (MIRT552162)
- hsa-mir-520c-3p (MIRT552163)
- hsa-mir-520b (MIRT552164)
- hsa-mir-520a-3p (MIRT552165)
- hsa-mir-373-3p (MIRT552166)
- hsa-mir-372-3p (MIRT552167)
- hsa-mir-302e (MIRT552168)
- hsa-mir-302d-3p (MIRT552169)
- hsa-mir-302c-3p (MIRT552170)
- hsa-mir-302b-3p (MIRT552171)
- hsa-mir-302a-3p (MIRT552172)
- hsa-mir-519c-3p (MIRT552173)
- hsa-mir-519b-3p (MIRT552174)
- hsa-mir-519a-3p (MIRT552175)
- hsa-mir-4668-3p (MIRT552177)
miRNA Products
- Search ViGene Biosciences for DAD1
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-
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
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-
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Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DAD1 Gene
Localization for DAD1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for DAD1 Gene
- Endoplasmic reticulum membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| endoplasmic reticulum | 5 |
| plasma membrane | 3 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005783 | endoplasmic reticulum | IEA | -- |
| GO:0005789 | endoplasmic reticulum membrane | IEA,TAS | -- |
| GO:0008250 | oligosaccharyltransferase complex | IEA,TAS | 15835887 |
| GO:0016020 | membrane | IDA,IEA | 19946888 |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for DAD1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism of proteins | ||
| 2 | Metabolism | ||
| 3 | N-Glycan biosynthesis | ||
| 4 | Protein processing in endoplasmic reticulum | ||
| 5 | Transport to the Golgi and subsequent modification | ||
Pathways by source for DAD1 Gene
3 Reactome pathways for DAD1 Gene
3 KEGG pathways for DAD1 Gene
1 GeneGo (Thomson Reuters) pathway for DAD1 Gene
UniProtKB/Swiss-Prot P61803-DAD1_HUMAN
- Pathway: Protein modification; protein glycosylation.
Interacting Proteins for DAD1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001824 | blastocyst development | IEA | -- |
| GO:0006486 | protein glycosylation | ISS,IEA | -- |
| GO:0006487 | protein N-linked glycosylation | IBA | -- |
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0007584 | response to nutrient | IEA | -- |
No data available for SIGNOR curated interactions for DAD1 Gene
Drugs & Compounds for DAD1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| L-Asparagine | Approved | Nutra | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Dolichyl diphosphate |
|
37247-98-6 |
|
Transcripts for DAD1 Gene
mRNA/cDNA for DAD1 Gene
- (1) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (334) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for DAD1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for DAD1
-
Santa Cruz Biotechnology (SCBT) CRISPR for DAD1
- GenScript: Design CRISPR guide RNA sequences for DAD1
miRNA Products
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Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for DAD1
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-
ViGene Biosciences ready-to-package AAV shRNAs for DAD1 gene
Clone Products
- Sino Biological Human cDNA Clone for DAD1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for DAD1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DAD1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||
| SP4: | |||||||||||||||||||||||
| SP5: | - | - | - | - |
Expression for DAD1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
- Brain (Nervous System)
- Intestine (Gastrointestinal Tract)
- Limb (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
-
Uterus (Reproductive System)
-
Colon (Gastrointestinal Tract)
-
Prostate (Endocrine System)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Kidney (Urinary System)
-
Testis (Reproductive System)
-
Adrenal Gland (Endocrine System)
-
Esophagus (Gastrointestinal Tract)
-
Stomach (Gastrointestinal Tract)
-
Liver (Hepatobiliary System)
-
Ovary (Reproductive System)
-
Adipose (Muscoskeletal System)
This gene is overexpressed in Nasal epithelium (32.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for DAD1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of DAD1 Gene:
DAD1SOURCE GeneReport for Unigene cluster for DAD1 Gene:
Hs.82890Evidence on tissue expression from TISSUES for DAD1 Gene
- Nervous system(4.8)
- Blood(4.4)
- Skin(4.4)
- Kidney(2.4)
- Thyroid gland(2.2)
- Adrenal gland(2.1)
- Gall bladder(2.1)
- Heart(2)
- Intestine(2)
- Liver(2)
- Lung(2)
- Lymph node(2)
- Muscle(2)
- Stomach(2)
Primer Products
-
OriGene qPCR primer pairs and template standards for DAD1
-
OriGene qPCR primer pairs for DAD1
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for DAD1 Gene
Orthologs for DAD1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | DAD1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | DAD1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | DAD1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Dad1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Dad1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | DAD1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | DAD1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | DAD1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | dad1 34 |
|
||
| Str.10052 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | LOC397721 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | dad1 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG13393 36 |
|
|
|
| l(2)k12914 34 35 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP008491 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | dad-1 36 34 35 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | OST2 35 37 |
|
OneToOne | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | ATDAD1 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os04g0397000 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5446 35 |
|
OneToOne |
- Species where no ortholog for DAD1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for DAD1 Gene
Pseudogenes.org Pseudogenes for DAD1 Gene
No data available for Paralogs for DAD1 Gene
Variants for DAD1 Gene
| SNP ID | Clin | Chr 14 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000099074 | -- | 22,565,540(+) | ACAGA(C/T)TTCCA | intron-variant | |
| rs1000137365 | -- | 22,581,560(+) | AACAT(A/G)GAGAA | intron-variant | |
| rs1000204462 | -- | 22,588,770(+) | CGTTT(C/G)GTATT | intron-variant | |
| rs1000474025 | -- | 22,582,961(+) | AGATT(A/G)TGCCA | intron-variant | |
| rs1000522752 | -- | 22,582,723(+) | ACAAC(C/T)GGCCG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2678511 | CNV | deletion | 23128226 |
| esv3633757 | CNV | loss | 21293372 |
| esv3892469 | CNV | gain+loss | 25118596 |
| nsv1047315 | CNV | gain | 25217958 |
| nsv519534 | CNV | loss | 19592680 |
| nsv563998 | CNV | gain | 21841781 |
| nsv832746 | CNV | gain | 17160897 |
| nsv832748 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
48.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.15;
3.33% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for DAD1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DAD1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DAD1 Gene
Disorders for DAD1 Gene
Relevant External Links for DAD1
No disorders were found for DAD1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DAD1 Gene
Publications for DAD1 Gene
- Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells. (PMID: 8413235) Nakashima T. … Nishimoto T. (Mol. Cell. Biol. 1993) 3 4 22 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- A Large-scale genetic association study of esophageal adenocarcinoma risk. (PMID: 20453000) Liu C.Y. … Christiani D.C. (Carcinogenesis 2010) 3 46 64
- An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PMID: 20677014) Shimada M. … Tokunaga K. (Hum. Genet. 2010) 3 46 64
- High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss. (PMID: 18383209) Kulke M.H. … Shivdasani R.A. (Genes Chromosomes Cancer 2008) 3 22 64
Products for DAD1 Gene
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for DAD1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer