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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DACT3 Gene

protein-coding   GIFtS: 47
GCID: GC19M047150

dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)

(Previous name: arginine rich region 1 )
(Previous symbol: RRR1)
 Explore 3 diseases affiliated with
DACT3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for DACT3    

Aliases
for DACT3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Dapper, Antagonist Of Beta-Catenin, Homolog 3 (Xenopus Laevis)1 2     Arginine-Rich Region 1 Protein2 3
RRR11 2 3     Dapper Antagonist Of Catenin 32 3
Arginine Rich Region 11 2     MGC154761
Antagonist Of Beta-Catenin Dapper Homolog 32 3     Dapper Homolog 32

External Ids:    HGNC: 307451   Entrez Gene: 1479062   Ensembl: ENSG000001973807   OMIM: 6111125   UniProtKB: Q96B183   

Export aliases for DACT3 gene to outside databases

Previous GC identifers: GC19M051844 GC19M043576


Summaries
for DACT3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: DACT3_HUMAN, Q96B18
Function: May be involved in regulation of intracellular signaling pathways during development. Specifically thought to
play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family
proteins




Genomic Views
for DACT3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DACT3 gene promoter:
         ER-alpha   TBP   AML1a   Pax-5   p53   Lmo2   CP2   TFIID   SEF-1 (1)   ZIC2/Zic2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: DACT3 promoter sequence
   Search SABiosciences Chromatin IP Primers for DACT3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DACT3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.32   Ensembl cytogenetic band:  19q13.32   HGNC cytogenetic band: 19q13.32

DACT3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DACT3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M047150:  view genomic region     (about GC identifiers)

Start:
 47,150,869 bp from pter      End:
 47,164,395 bp from pter
Size:
 13,527 bases      Orientation:
 minus strand

Proteins
for DACT3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: DACT3_HUMAN, Q96B18 (See protein sequence)
Recommended Name: Dapper homolog 3  
Size: 629 amino acids; 64949 Da
Subunit: Can form homodimers and heterodimers with DACT1 or DACT3. Interacts with CSNK1D, PKA catalytic subunit,
PKC-type kinase, DVL1, DVL3, VANGL1, VANGL2 and CTNND1 (By similarity). Interacts with DVL2
Sequence caution: Sequence=AAH16161.1; Type=Frameshift; Positions=119;

Explore the universe of human proteins at neXtProt for DACT3: NX_Q96B18

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96B18

    • DACT3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_659493.2  
    ENSEMBL proteins: 
     ENSP00000300875   ENSP00000375783   ENSP00000387300  

    Human Recombinant Protein Products: 
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    Novus Biologicals DACT3 Protein
    Novus Biologicals DACT3 Lysate
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    Uscn Proteins for DACT3


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    Uscn ELISAs and CLIAs for DACT3

    Protein Domains /
    Families
    for DACT3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    DACT3 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR024844 Dact3
     IPR024843 Dapper

    Graphical View of Domain Structure for InterPro Entry Q96B18

    ProtoNet protein and cluster: Q96B18

    UniProtKB/Swiss-Prot: DACT3_HUMAN, Q96B18
    Domain: The C-terminal PDZ-binding motif may mediate interaction with the PDZ domains of DSH (Dishevelled) family
    proteins (By similarity)
    Similarity: Belongs to the dapper family


    Function
    for DACT3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: DACT3_HUMAN, Q96B18
    Function: May be involved in regulation of intracellular signaling pathways during development. Specifically thought to
    play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family
    proteins

    miRNA
    Products:            		miRTarBase miRNAs that target DACT3:
    hsa-mir-31 (MIRT005875)

    OriGene 3'-UTR Clone: DACT3
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DACT3
    8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate DACT3 (see all 29):
    hsa-miR-3934 hsa-miR-520d-5p hsa-miR-181c* hsa-miR-1285 hsa-miR-1205 hsa-miR-1257 hsa-miR-373* hsa-miR-583
    SwitchGear 3'UTR luciferase reporter plasmid: DACT3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DACT3 (see all 4)
    OriGene shRNA RFP: DACT3
    OriGene siRNA: DACT3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DACT3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for DACT3

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for DACT3 (see all 3)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DACT3 

    Cell Line
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    Search LifeMap BioReagents cell lines for DACT3

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DACT3

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005080protein kinase C binding ISS--
    GO:0051018protein kinase A binding ISS--
    GO:0070097delta-catenin binding ISS--


    DACT3 for ontologies           About GeneDecksing



    Pathways & Interactions
    for DACT3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DACT3

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/6 Interacting proteins for DACT3 (Q96B183 ENSP000003757834) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SH3GLB2Q9NR463I2D: score=1 
    VANGL2ENSP000003570404STRING: ENSP00000357040
    VANGL1ENSP000003108004STRING: ENSP00000310800
    DVL3ENSP000003160544STRING: ENSP00000316054
    DVL1ENSP000003681694STRING: ENSP00000368169
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016055Wnt receptor signaling pathway IEA--
    GO:0030178negative regulation of Wnt receptor signaling pathway IDA18538736
    GO:0030308negative regulation of cell growth IDA18538736
    GO:0035414negative regulation of catenin import into nucleus IDA18538736


    DACT3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for DACT3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DACT3
    Search CenterWatch for drugs/clinical trials and news about DACT3 

    Transcripts
    for DACT3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for DACT3 gene: 
    NM_145056.2  

    Unigene Cluster for DACT3:

    Dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
    Hs.515490  [show with all ESTs]
    Unigene Representative Sequence: NM_145056
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000300875 ENST00000391916(uc010ekq.3) ENST00000410105(uc002pfb.3)


    miRNA
    Products:             		 OriGene 3'-UTR Clone: DACT3
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat DACT3
    8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate DACT3 (see all 29):
    hsa-miR-3934 hsa-miR-520d-5p hsa-miR-181c* hsa-miR-1285 hsa-miR-1205 hsa-miR-1257 hsa-miR-373* hsa-miR-583
    SwitchGear 3'UTR luciferase reporter plasmid: DACT3 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for DACT3 (see all 4)
    OriGene shRNA RFP: DACT3
    OriGene siRNA: DACT3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DACT3
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for DACT3 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: DACT3 (NM_145056)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DACT3 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DACT3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DACT3

    Additional cDNA sequence: BC016161.1 

    4 DOTS entries:

    DT.97801727  DT.109829  DT.100020005  DT.91989023 

    24/54 AceView cDNA sequences (see all 54):

    AI871500 AI039431 AI333428 AI076469 BF115250 AW027376 AI079827 AI761701 
    AI141140 CB051231 CD672028 CD672022 BM726884 BC034052 AI129213 W72525 
    AI963930 BI603646 AI951237 AI458010 AI553837 AI809234 AA663607 AW027732 

    GeneLoc Exon Structure


    Expression
    for DACT3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DACT3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACCCCCACTC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    DACT3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyAfferent ArterioleJuxtaglomerular CellsKidney, Smooth Muscle
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 5 LifeMap Cells 
    NameCategory
    PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)Heart, Myocardium, Smooth Muscle
    PureStem™ mesenchymal Progenitor SK11 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor SM30 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor 7SMOO32 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor 4D20.8 (Embryonic Progenitor Cell)Lateral Plate Mesoderm, Neural Crest

    See DACT3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DACT3

    SOURCE GeneReport for Unigene cluster: Hs.515490
        SABiosciences Custom PCR Arrays for DACT3
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DACT3

    Orthologs
    for DACT3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for DACT3 gene from 3/5 species (see all 5)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Dact31 , 5 dapper homolog 3, antagonist of beta-catenin (xenopus)1, 5 83.91(n)1
    89.42(a)1    		   7 (9.15 cM)5
    6293781  NM_001081655.11  NP_001075124.11 
     168753175 
    lizard
    (Anolis carolinensis)    		 Reptilia DACT36
    		 --
    		 45(a)
    		 1 ↔ 1
    		 AAWZ02039310(859-4989)
    zebrafish
    (Danio rerio)    		 Actinopterygii si:ch211-242f23.76
    CABZ01041493.16
    		 --
    		 32(a)
    24(a)
    		 many → 1
    many → 1
    		 10(407728-422464)
    18(45219884-45238864)


    ENSEMBL Gene Tree for DACT3 (if available)
    TreeFam Gene Tree for DACT3 (if available) 

    Paralogs
    for DACT3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DACT3 gene
    DACT12  DACT22  

    DACT3 for paralogs           About GeneDecksing



    Genomic Variants
    for DACT3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/262 NCBI SNPs in DACT3 are shown (see all 262)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1115454301,2
    		--47150403(+) ATCCAC/TGCTGG 1 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs1829288131,2
    		--47150409(+) GCTGGC/TGTGCA 1 -- ds50010--------
    rs104219871,2
    		C,--47150594(+) GCTCAA/GGATAT 1 -- ds50015Minor allele frequency- G:0.08NA WA EA 244
    rs1451109531,2
    		--47150767(+) CCTGG-/AAAACT 1 -- ds50010--------
    rs1391164651,2
    		C,--47150770(+) GGAAA-/CCTGCC 1 -- ds50010--------
    rs1871331811,2
    		--47150807(+) AATAAA/GTGTTA 1 -- ds50010--------
    rs1429360791,2
    		--47150827(+) AAAAAG/TAGCAT 1 -- ds50010--------
    rs1389264101,2
    		--47150908(+) GAGAA-/ACACACA 1 -- ut310--------
    rs455062031,2
    		--47150935(+) TTTGCA/GCTGGG 1 -- ut310--------
    rs1906253541,2
    		--47151103(+) CCTCCA/GTAATT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for DACT3 (47150869 - 47164395 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for DACT3: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing DACT3
    DNA2.0 Custom Variant and Variant Library Synthesis for DACT3

    Disorders / Diseases
    for DACT3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    DACT3 for disorders           About GeneDecksing

    OMIM gene information: 611112    OMIM disorders: --

    3 diseases for DACT3:    About MalaCards
    placenta praevia    yellow fever    colorectal cancer

    1 disease from the University of Copenhagen DISEASES database for DACT3:
    Placenta praevia

    Export disorders for DACT3 gene to outside databases

    Publications
    for DACT3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DACT3 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with DACT3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Three Dact gene family members are expressed during embryonic development and in the adult brains of mice. (PubMed id 16881060)1, 2, 3 Fisher D.A.... Cheyette B.N.R. (2006)
    2. DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. (PubMed id 18538736)1, 2 Jiang X....Yu Q. (2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases. (PubMed id 21718540)1 Kivimae S....Cheyette B.N. (2011)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for DACT3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing DACT3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 147906 HGNC: 30745 AceView: MGC15476 Ensembl:ENSG00000197380 euGenes: HUgn147906
    ECgene: DACT3 H-InvDB: DACT3

    Other Databases showing DACT3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing DACT3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DACT3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for DACT3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for DACT3 gene:
    Search GeneIP for patents involving DACT3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for DACT3 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
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     OriGene Antibodies for DACT3   OriGene shRNA RFP for DACT3  
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat DACT3
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     Regulatory tfbs in DACT3 promoter
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     Novus Tissue Slides
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     Search for Antibodies for DACT3 at Abcam
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     DACT3 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for DACT3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DACT3
     SwitchGear 3'UTR luciferase reporter plasmids for DACT3
     SwitchGear Promoter luciferase reporter plasmids for DACT3
     ThermoFisher Antibodies for DACT3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DACT3
           
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