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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DACT2 Gene

protein-coding   GIFtS: 51
GCID: GC06M168693

Dishevelled-Binding Antagonist Of Beta-Catenin 2

(Previous names: chromosome 6 open reading frame 116, dapper homolog 2, antagonist...)
(Previous symbol: C6orf116)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dishevelled-Binding Antagonist Of Beta-Catenin 21 2     Dapper, Antagonist Of Beta-Catenin, Homolog 2 (Xenopus Laevis)1
C6orf1161 2 3     RP11-503C24.72
Dapper Antagonist Of Catenin 22 3     bA503C24.72
DAPPER22 5     Dapper Homolog 22
DPR22 5     Dapper Homolog 2, Antagonist Of Beta-Catenin2
Chromosome 6 Open Reading Frame 1161     Dapper, Antagonist Of Beta-Catenin, Homolog 22
Dapper Homolog 2, Antagonist Of Beta-Catenin (Xenopus)1     

External Ids:    HGNC: 212311   Entrez Gene: 1680022   Ensembl: ENSG000001644887   OMIM: 6089665   UniProtKB: Q5SW243   

Export aliases for DACT2 gene to outside databases

Previous GC identifers: GC06M168389 GC06M168465 GC06M168526 GC06M166135


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DACT2 Gene: 
DACT2 (dishevelled-binding antagonist of beta-catenin 2) is a protein-coding gene. Diseases associated with DACT2 include adenoma. GO annotations related to this gene include protein kinase C binding and transcription factor binding. An important paralog of this gene is DACT1.

UniProtKB/Swiss-Prot: DACT2_HUMAN, Q5SW24
Function: Involved in regulation of intracellular signaling pathways during development. Negatively regulates the
Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May
be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and
restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds
by attenuating TGF-beta signaling (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_025741.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DACT2 gene promoter:
         Tal-1   AP-4   Ik-3   Tal-1beta   AREB6   Ik-2   FOXO4   FOXO1a   ITF-2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDACT2 promoter sequence
   Search SABiosciences Chromatin IP Primers for DACT2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DACT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q27   Ensembl cytogenetic band:  6q27   HGNC cytogenetic band: 6q27

DACT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DACT2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M168693:  view genomic region     (about GC identifiers)

Start:
168,693,512 bp from pter      End:
168,720,434 bp from pter
Size:
26,923 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DACT2_HUMAN, Q5SW24 (See protein sequence)
Recommended Name: Dapper homolog 2  
Size: 774 amino acids; 82700 Da
Subunit: Can form homodimers and heterodimers with DACT1 or DACT3. Interacts with CSNK1D, PKA catalytic subunit,
PKC-type kinase, CSNK2B, DVL1, DVL2, DVL3, VANGL1, VANGL2, TGFBR1, CTNNB1, CTNND2, CTNND1, LEF1, TCF7, TCF7L1 and
HDAC1 (By similarity)
Sequence caution: Sequence=AAI11791.1; Type=Erroneous initiation; Sequence=AAL55843.1; Type=Frameshift;
Positions=247;
Secondary accessions: Q2NKJ2 Q569G0 Q8WYW2
Alternative splicing: 4 isoforms:  Q5SW24-1   Q5SW24-2   Q5SW24-3   Q5SW24-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for DACT2: NX_Q5SW24

Explore proteomics data for DACT2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5SW24

  • DACT2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DACT2 Protein Expression
    REFSEQ proteins: NP_999627.2  
    ENSEMBL proteins: 
     ENSP00000355760   ENSP00000355761  

    Human Recombinant Protein Products for DACT2: 
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    Novus Biologicals DACT2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for DACT2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--

    DACT2 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for DACT2 
    Cloud-Clone Corp. CLIAs for DACT2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR024843 Dapper
     IPR024853 Dact2

    Graphical View of Domain Structure for InterPro Entry Q5SW24

    ProtoNet protein and cluster: Q5SW24

    UniProtKB/Swiss-Prot: DACT2_HUMAN, Q5SW24
    Domain: The C-terminal PDZ-binding motif may mediate interaction with the PDZ domains of DSH (Dishevelled) family
    proteins (By similarity)
    Similarity: Belongs to the dapper family


    DACT2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DACT2_HUMAN, Q5SW24
    Function: Involved in regulation of intracellular signaling pathways during development. Negatively regulates the
    Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May
    be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and
    restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds
    by attenuating TGF-beta signaling (By similarity)

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005080protein kinase C binding ISS--
    GO:0005515protein binding ----
    GO:0008013beta-catenin binding ISS--
    GO:0008134transcription factor binding ISS--
    GO:0051018protein kinase A binding ISS--
         
    DACT2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for DACT2:
     Increased cell number in G2M,  

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Dact2):
     homeostasis/metabolism  integument 

    DACT2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Dact2tm1.1Xya for DACT2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for DACT2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for DACT2

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    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DACT2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DACT2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1TGF-beta receptor signaling
    TGF-beta receptor signaling


    1 BioSystems Pathway for DACT2
        TGF-beta receptor signaling



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DACT2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for DACT2 (ENSP000003557604) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    VANGL1ENSP000003108004STRING: ENSP00000310800
    VANGL2ENSP000003570404STRING: ENSP00000357040
    DVL3ENSP000003160544STRING: ENSP00000316054
    DVL1ENSP000003681694STRING: ENSP00000368169
    CTNND1ENSP000003820044STRING: ENSP00000382004
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003382epithelial cell morphogenesis ISS--
    GO:0007162negative regulation of cell adhesion ISS--
    GO:0043588skin development ISS--
    GO:0072061inner medullary collecting duct development ISS--
    GO:1900108negative regulation of nodal signaling pathway ISS--

    DACT2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DACT2

    Search CenterWatch for drugs/clinical trials and news about DACT2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DACT2 gene: 
    NM_214462.3  

    Unigene Cluster for DACT2:

    Dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)
    Hs.673059  [show with all ESTs]
    Unigene Representative Sequence: AF318336
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366795(uc003qwq.3) ENST00000366796
    miRNA
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    Inhib. RNA
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DACT2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DACT2

    Additional mRNA sequence: 

    AF318336.1 BC092498.1 BC111764.1 BC111790.1 

    4 DOTS entries:

    DT.95284991  DT.95290084  DT.121309291  DT.121309299 

    10 AceView cDNA sequences:

    CR624566 AF318336 NM_214462 BI052777 BX377941 AW629887 CF994844 AW150833 
    BX329974 BI769958 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DACT2 expression in normal human tissues (normalized intensities)      DACT2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCTCAAATA
    DACT2 Expression
    About this image


    DACT2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Gut Tube (Gastrointestinal Tract)    fully expand to see all 3 entries
             Midgut
             Definitive endoderm-like cells ( A scalable, suspension protocol for derivation of...
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             visceral organ/metanephros/calyx   
     
     Lower Urinary Tract (Urinary System)    fully expand to see all 2 entries
             visceral organ/metanephros/calyx   
     
     Brain (Nervous System)    fully expand to see all 2 entries
             putamen   
     
     Placenta (Extraembryonic Tissues)
             placenta   

    See DACT2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DACT2

    SOURCE GeneReport for Unigene cluster: Hs.673059
        SABiosciences Custom PCR Arrays for DACT2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DACT2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for DACT2 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Dact21 , 5 dapper homolog 2, antagonist of beta-catenin (xenopus)1, 5 68.1(n)1
    59.3(a)1
      17 (8.95 cM)5
    2400251  NM_172826.31  NP_766414.31 
     141952315 
    chicken
    (Gallus gallus)
    Aves DACT21 dapper, antagonist of beta-catenin, homolog 2 (Xenopus more 56.02(n)
    46.58(a)
      421561  XM_419602.3  XP_419602.3 
    lizard
    (Anolis carolinensis)
    Reptilia DACT26
    --
    --
    38(a)
    18(a)
    1 ↔ 1
    possible ortholog
    1(224625963-224644378)
    GL343928.1(74378-90301)
    zebrafish
    (Danio rerio)
    Actinopterygii wufe24f122 Danio rerio Frodo2 (frd2) mRNA, complete cds 72.67(n)    AY208969.2 


    ENSEMBL Gene Tree for DACT2 (if available)
    TreeFam Gene Tree for DACT2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DACT2 gene
    DACT12  

    DACT2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/436 SNPs in DACT2 are shown (see all 436)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1453974151,2
    --166149096(+) TTTCCA/GAGATT 1 -- int10--------
    rs1484729051,2
    C--166149127(+) TTTGA-/TTCTTT
            
    TTTCT
    1 -- int10--------
    rs1999060571,2
    C--166149129(+) TGATTC/TTTTTT 1 -- int10--------
    rs2008977841,2
    C--166149130(+) GATTCC/TTTTTT 1 -- int10--------
    rs94560551,2
    C,A--166149133(+) tctttC/Tttctt 1 -- int1 trp33Minor allele frequency- T:0.00NA WA CSA 5
    rs122059311,2
    --166149161(+) tcttcC/Ttcttc 1 -- int1 trp30--------
    rs122059331,2
    --166149167(+) tcttcC/Ttcttc 1 -- int10--------
    rs47087141,2
    C,H--168707127(+) CCCCTT/CTTTTT 1 -- ds5001 trp36Minor allele frequency- C:0.01NA WA EA 130
    rs69401451,2
    C,A,H--168707161(+) TCTGTT/AGCCCA 1 -- ds50011Minor allele frequency- A:0.50NA 2
    rs1138756311,2
    C,F--168707162(+) CTGTAG/CCCCAA 1 -- ds50012Minor allele frequency- C:0.50WA NA 4

    HapMap Linkage Disequilibrium report for DACT2 (168693512 - 168720434 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/23 variations for DACT2 (see all 23):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv1088e201CNV Deletion23290073
    dgv1087e201CNV Deletion23290073
    esv2733340CNV Deletion23290073
    esv4977CNV Deletion18987735
    esv2155452CNV Deletion18987734
    dgv1089e201CNV Deletion23290073
    nsv820984CNV Deletion20802225
    esv2618324CNV Deletion19546169
    esv1675508CNV Deletion17803354
    esv2733341CNV Deletion23290073

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing DACT2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608966    OMIM disorders: --

    2 diseases for DACT2:    About MalaCards
    adenoma    


    DACT2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): DACT2
    Human Genome Epidemiology (HuGE) Navigator: DACT2 (2 documents)

    Export disorders for DACT2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DACT2 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with DACT2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer. (PubMed id 22806826)1 Jia Y....Guo M. (2013)
    4. Relationships among MTHFR a1298c gene polymorphisms an d methylation status of Dact1 gene in transitional cell carcinomas. (PubMed id 23244112)1 Cheng H....Chen J.C. (2012)
    5. All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases. (PubMed id 21718540)1 Kivimae S....Cheyette B.N. (2011)
    6. Flat adenoma-carcinoma sequence with high-malignancy potential as demonstrated by CD10 and beta-catenin expression: a different pathway from the polypoid adenoma-carcinoma sequence. (PubMed id 18370954)1 Koga Y....Tsuneyoshi M. (2008)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)2 Wan D....Gu J. (2004)
    9. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (2003)
    10. Identification and characterization of human DAPPER1 and DAPPER2 genes in silico. (PubMed id 12632086)1 Katoh M. and Katoh M. (2003)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 168002 HGNC: 21231 AceView: DACT2 Ensembl:ENSG00000164488 euGenes: HUgn168002
    ECgene: DACT2 H-InvDB: DACT2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DACT2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DACT2 gene:
    Search GeneIP for patents involving DACT2

    GeneCards and IP:
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