Aliases for DACT2 Gene
Aliases for DACT2 Gene
- Dishevelled Binding Antagonist Of Beta Catenin 2 2 3 5
- Dapper Antagonist Of Catenin 2 3 4
- C6orf116 3 4
- Dapper, Antagonist Of Beta-Catenin, Homolog 2 (Xenopus Laevis) 2
- Dapper Homolog 2, Antagonist Of Beta-Catenin (Xenopus) 2
- Dapper, Antagonist Of Beta-Catenin, Homolog 2 3
- Dapper Homolog 2, Antagonist Of Beta-Catenin 3
External Ids for DACT2 Gene
- HGNC: 21231
- Entrez Gene: 168002
- Ensembl: ENSG00000164488
- OMIM: 608966
- UniProtKB: Q5SW24
Previous HGNC Symbols for DACT2 Gene
- C6orf116
Previous GeneCards Identifiers for DACT2 Gene
- GC06M168389
- GC06M168465
- GC06M168526
- GC06M168693
- GC06M166135
Summaries for DACT2 Gene
GeneCards Summary for DACT2 Gene
DACT2 (Dishevelled Binding Antagonist Of Beta Catenin 2) is a Protein Coding gene. Among its related pathways are TGF-beta receptor signaling (Pathway Interaction Database). GO annotations related to this gene include transcription factor binding and protein kinase C binding. An important paralog of this gene is DACT1.
UniProtKB/Swiss-Prot for DACT2 Gene
-
Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for DACT2 Gene
Genomics for DACT2 Gene
Regulatory Elements for DACT2 Gene
Enhancers for DACT2 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH06G168325 | 1 | ENCODE | 27.2 | -7.1 | -7054 | 2.4 | FOXA2 MLX ARID4B DMAP1 ZNF48 SLC30A9 GATA2 SP5 MIER2 PPARG | DACT2 LOC105378139 |
| GH06G168369 | 0.8 | ENCODE | 22 | -50.5 | -50540 | 0.7 | ELF3 RB1 MLX CREB3L1 KLF17 ZNF48 RAD21 ZNF143 ZNF391 CREM | DACT2 ENSG00000260771 LOC105378139 |
| GH06G168332 | 0.7 | ENCODE | 20.9 | -14.1 | -14081 | 1.8 | CTCF KLF1 ATF1 CBX3 NRF1 ZNF175 ZNF76 ELF4 ELF1 RAD21 | DACT2 SMOC2 LOC105378139 |
| GH06G168318 | 0.7 | ENCODE | 16.9 | +1.0 | 1030 | 1.2 | SOX5 SOX13 GATAD2A PKNOX1 FOXA2 SP5 SUZ12 FOXA3 RBBP5 RARA | DACT2 LOC105378138 |
| GH06G168333 | 0.6 | ENCODE | 17.4 | -12.4 | -12442 | 1.2 | NCOR1 HLF MAX ZIC2 MAFK ZKSCAN1 | DACT2 LOC105378139 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around DACT2 on UCSC Golden Path with GeneCards custom track
Promoters for DACT2 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|---|---|---|
| ENSR00000207053 | 54 | 601 | SUZ12 RBBP5 |
Regulatory Element Products
Genomic Location for DACT2 Gene
- Chromosome:
- 6
- Start:
- 168,292,830 bp from pter
- End:
- 168,319,754 bp from pter
- Size:
- 26,925 bases
- Orientation:
- Minus strand
Genomic View for DACT2 Gene
Genes around DACT2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6q27 by Ensembl
- 6q27 by Entrez Gene
- 6q27 by HGNC
DACT2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DACT2 Gene
Proteins for DACT2 Gene
-
Protein details for DACT2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5SW24-DACT2_HUMAN
- Recommended name:
- Dapper homolog 2
- Protein Accession:
- Q5SW24
- Q2NKJ2
- Q569G0
- Q8WYW2
Protein attributes for DACT2 Gene
- Size:
- 774 amino acids
- Molecular mass:
- 82700 Da
- Quaternary structure:
-
- Can form homodimers and heterodimers with DACT1 or DACT3. Interacts with CSNK1D, PKA catalytic subunit, PKC-type kinase, CSNK2B, DVL1, DVL2, DVL3, VANGL1, VANGL2, TGFBR1, CTNNB1, CTNND2, CTNND1, LEF1, TCF7, TCF7L1 and HDAC1 (By similarity).
- SequenceCaution:
-
- Sequence=AAI11791.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAL55843.1; Type=Frameshift; Positions=247; Evidence={ECO:0000305};
Protein Expression for DACT2 Gene
Post-translational modifications for DACT2 Gene
Other Protein References for DACT2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for DACT2
- Novus Biologicals Antibodies for DACT2
-
Abcam antibodies for DACT2
- Invitrogen Antibodies for DACT2
- antibodies-online Antibodies for DACT2: See all 15
- GeneTex DACT2 antibody for DACT2
-
Custom Antibody ServicesProSci Antibodies for DACT2
Protein Products
-
OriGene Purified Proteins for DACT2
- Search Origene for MassSpec and Protein Over-expression Lysates for DACT2
- Origene Custom Protein Services for DACT2
- antibodies-online Proteins for DACT2: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for DACT2
-
Abcam proteins for DACT2
Assay Products
No data available for DME Specific Peptides for DACT2 Gene
Domains & Families for DACT2 Gene
Suggested Antigen Peptide Sequences for DACT2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q5SW24UniProtKB/Swiss-Prot:
DACT2_HUMAN :- The C-terminal PDZ-binding motif may mediate interaction with the PDZ domains of DSH (Dishevelled) family proteins.
- Belongs to the dapper family.
- Domain:
-
- The C-terminal PDZ-binding motif may mediate interaction with the PDZ domains of DSH (Dishevelled) family proteins.
- Family:
-
- Belongs to the dapper family.
No data available for Gene Families for DACT2 Gene
Function for DACT2 Gene
Molecular function for DACT2 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005080 | protein kinase C binding | ISS,IBA | -- |
| GO:0008013 | beta-catenin binding | IBA,ISS | -- |
| GO:0008134 | transcription factor binding | ISS | -- |
| GO:0051018 | protein kinase A binding | IBA,ISS | -- |
| GO:0070097 | delta-catenin binding | ISS,IBA | -- |
Phenotypes for DACT2 Gene
- MGI mutant phenotypes for DACT2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for DACT2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for DACT2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for DACT2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DACT2 gene
- Search ViGene Biosciences for DACT2
CRISPR Products
-
OriGene CRISPR knockouts for DACT2
-
Santa Cruz Biotechnology (SCBT) CRISPR for DACT2
- GenScript: Design CRISPR guide RNA sequences for DACT2
miRNA for DACT2 Gene
- miRTarBase miRNAs that target DACT2
miRNA Products
- Search ViGene Biosciences for DACT2
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for DACT2
- Browse OriGene Inhibitory RNA Products For DACT2
-
ViGene Biosciences ready-to-package AAV shRNAs for DACT2 gene
Clone Products
- Sino Biological Human cDNA Clone for DACT2
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- VectorBuilder custom plasmid, inducible vectors for DACT2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DACT2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for DACT2
-
ViGene Biosciences adenoviral particle packaged cDNA for DACT2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for DACT2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for DACT2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DACT2 Gene
Localization for DACT2 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 3 |
| mitochondrion | 2 |
| extracellular | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IBA | -- |
| GO:0005739 | mitochondrion | IEA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for DACT2 Gene
Pathways & Interactions for DACT2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | TGF-beta receptor signaling (Pathway Interaction Database) | ||
Pathways by source for DACT2 Gene
1 BioSystems pathway for DACT2 Gene
Interacting Proteins for DACT2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002244 | hematopoietic progenitor cell differentiation | IEA | -- |
| GO:0003382 | epithelial cell morphogenesis | ISS | -- |
| GO:0007162 | negative regulation of cell adhesion | ISS | -- |
| GO:0030111 | regulation of Wnt signaling pathway | IBA | -- |
| GO:0043588 | skin development | ISS | -- |
Transcripts for DACT2 Gene
mRNA/cDNA for DACT2 Gene
- (4) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (10) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for DACT2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for DACT2
-
Santa Cruz Biotechnology (SCBT) CRISPR for DACT2
- GenScript: Design CRISPR guide RNA sequences for DACT2
miRNA Products
- Search ViGene Biosciences for DACT2
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for DACT2
- Browse OriGene Inhibitory RNA Products For DACT2
-
ViGene Biosciences ready-to-package AAV shRNAs for DACT2 gene
Clone Products
- Sino Biological Human cDNA Clone for DACT2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for DACT2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DACT2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for DACT2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Gut Tube (Gastrointestinal Tract)
-
Eye (Sensory Organs)
- Glycinergic Amacrine Cells Inner Nuclear Layer
-
Neurons
- Glycinergic Amacrine Cells Inner Nuclear Layer
- Bone (Muscoskeletal System)
- Endoderm (Gastrulation Derivatives)
- Primitive Streak (Early Embryonic Tissues)
-
Placenta (Extraembryonic Tissues)
mRNA differential expression in normal tissues according to GTEx for DACT2 Gene
This gene is overexpressed in Brain - Putamen (basal ganglia) (x8.5), Brain - Nucleus accumbens (basal ganglia) (x8.4), and Brain - Caudate (basal ganglia) (x7.2).
This gene is overexpressed in Pancreatic juice (62.0) and Placenta (7.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for DACT2 Gene
NURSA nuclear receptor signaling pathways regulating expression of DACT2 Gene:
DACT2SOURCE GeneReport for Unigene cluster for DACT2 Gene:
Hs.673059Primer Products
-
OriGene qPCR primer pairs for DACT2
No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DACT2 Gene
Orthologs for DACT2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | DACT2 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | DACT2 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Dact2 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Dact2 34 16 35 |
|
||
| cow (Bos Taurus) |
Mammalia | DACT2 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | DACT2 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | DACT2 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | DACT2 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | dact2 35 |
|
OneToOne | |
| wufe24f12 34 |
|
- Species where no ortholog for DACT2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for DACT2 Gene
Variants for DACT2 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000054867 | -- | 168,308,852(+) | GGAAC(A/G)AGGGG | intron-variant, reference, missense | |
| rs1000084367 | -- | 168,301,920(+) | CTTCA(C/T)TCCCG | intron-variant | |
| rs1000269047 | -- | 168,300,681(+) | AGAAT(A/G)TTCTG | intron-variant | |
| rs1000298391 | -- | 168,300,823(+) | ATGCT(A/C)AAGAT | intron-variant | |
| rs1000304177 | -- | 168,313,005(+) | AGGGG(C/T)CTCCC | intron-variant, upstream-variant-2KB |
Gene Damage Index Score:
7.32;
81.47% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for DACT2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DACT2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DACT2 Gene
Disorders for DACT2 Gene
Relevant External Links for DACT2
No disorders were found for DACT2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DACT2 Gene
Publications for DACT2 Gene
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 46 64
- Aberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma. (PMID: 28077137) Guo Y.L. … Kuang G. (J. Biomed. Sci. 2017) 3 64
- Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling. (PMID: 26919254) Zhang M. … Guo M. (Oncotarget 2016) 3 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
Products for DACT2 Gene
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
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- Custom Antibody ServicesOriGene Antibodies for DACT2
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- OriGene qPCR primer pairs for DACT2
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- GenScript: Design CRISPR guide RNA sequences for DACT2
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- Novus Biologicals Antibodies for DACT2
- Novus Biologicals proteins and lysates for DACT2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for DACT2
- Abcam proteins for DACT2
- Search for Assays for DACT2 at Abcam
- Find your target
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- antibodies-online Antibodies for DACT2: See all 15
- Search antibodies-online for kits
- antibodies-online Proteins for DACT2: See all 3
- Search antibodies-online for peptides
- GeneTex DACT2 antibody for DACT2
- Search GeneTex for Proteins for DACT2
- ViGene Biosciences adenoviral particle packaged cDNA for DACT2 gene
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- Search ViGene Biosciences for DACT2
- Custom Antibody ServicesProSci Antibodies for DACT2
- Search for DACT2 Proteins at ProSci
- Horizon Cell Lines for DACT2
- Cyagen custom Knockout/knockin (KOKI) mouse models for DACT2
- VectorBuilder custom plasmid, inducible vectors for DACT2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for DACT2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for DACT2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer