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DACH1 Gene

protein-coding   GIFtS: 51

GC13M070910
dachshund homolog 1 (Drosophila)
(Previous name: dachshund homolog (Drosophila) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: DACH)
Services    

Aliases &
Descriptions
for DACH1

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
DACH 2, 3
Dach1 3
FLJ10138 2
OTTHUMP00000018493 2
OTTHUMP00000040839 2
Descriptions
dachshund homolog (Drosophila) 1
dachshund homolog 1 2
dachshund homolog 1 (Drosophila) 2
External Ids
HGNC: 26631
Entrez Gene: 16022
UniProtKB: Q9UI363
Ensembl: ENSG000001656597
Search outside databases for aliases for DACH1 gene

Previous GC identifer: GC13M069811

Summaries
for DACH1

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for DACH1:
This gene is similar to the Drosophila melanogaster dachshund gene, which encodes a nuclear factor
essential for determining cell fates in the eye, leg, and nervous system of the fly. It is a
member of the Ski gene family and is thought to be involved in eye development. Four alternatively
spliced transcripts encoding different isoforms have been described for this gene. [provided by
RefSeq]

UniProtKB/Swiss-Prot: DACH1_HUMAN, Q9UI36
Function: Transcription factor that is involved in regulation of organogenesis. Seems to be a
regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in
myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1
complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a
corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase
inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through
interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity)

Gene Wiki entry for DACH1

Genomic Location
for DACH1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the DACH1 gene  

Entrez Gene cytogenetic band: 13q22   Ensembl cytogenetic band:  13q21.33   HGNC cytogenetic band: 13q22

DACH1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M070910:     (about GC identifiers)

Start:
 70,910,099 bp from pter
End:
 71,339,331 bp from pter
Size:
 429,233 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000013.9  NT_024524.13  

Proteins
for DACH1

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: DACH1_HUMAN, Q9UI36 (See protein sequence)
Recommended Name: Dachshund homolog 1  
Size: 758 amino acids; 78562 Da
Subunit: Interacts with SIX1, SIX6 and EYA3. Interacts with NCOR1 and HDAC3 through its N-terminus.
Interacts with SIN3A through its C-terminus (By similarity). Interacts with SMAD3 and SMAD4
Subcellular location: Nucleus
Sequence caution: Sequence=CAC12840.2; Type=Erroneous gene model prediction; Sequence=CAH73005.1;
Type=Erroneous gene model prediction; Sequence=CAH73006.1; Type=Erroneous gene model prediction;
Sequence=CAH73303.1; Type=Erroneous gene model prediction; Sequence=CAH73304.1; Type=Erroneous
gene model prediction; Sequence=CAI14979.1; Type=Erroneous gene model prediction;
Sequence=CAI14980.1; Type=Erroneous gene model prediction; Sequence=CAI16673.1; Type=Erroneous
gene model prediction;
PDB structures from and Proteopedia :
1L8R (3D)    
Secondary accessions: O75523 O75687 Q5VYY3 Q5VYY4 Q96SG3 Q96SG4 Q9H524 Q9UMH4
Alternative splicing: 4 isoforms:  Q9UI36-1   Q9UI36-2   Q9UI36-3   Q9UI36-4   (Additional isoforms seem to exist)

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (3 alternative transcripts): 
    NP_004383.2  NP_542937.1  NP_542938.1  


    ENSEMBL proteins: 
    ENSP00000367057 ENSP00000383153 ENSP00000304994 ENSP00000346604 ENSP00000318506 ENSP00000352712 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (DACH1)
    Human Recombinant Proteins from Abnova (DACH1)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IEA--
    GO:0005667 transcription factor complex IEA--
    GO:0005737 cytoplasm IEA--
    About this table

    Antibodies for DACH1: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for DACH1
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (DACH1), each with their AbpromiseSM
    Browse Abnova for Monoclonal and Polyclonal Antibodies
    Search Novus for antibodies for DACH1

    Assays for DACH1: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for DACH1

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro domain/family:
     IPR003380 Transform_Ski


       GeneDecks  DACH1 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q9UI36

    ProtoNet protein and cluster: Q9UI36

    UniProtKB/Swiss-Prot: DACH1_HUMAN, Q9UI36
    Domain: The DACHbox-N/DD1 domain forms a structure containing a DNA binding motif similar to that
    of the forkhead/winged helix domain
    Similarity: Belongs to the DACH/dachshund family

    Gene Function
    for DACH1

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (DACH1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (DACH1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_004392

                  Applied Biosystems Silencer® siRNAs for DACH1

                  Sigma-Aldrich siRNA for DACH1  
                         Sigma-Aldrich shRNA for DACH1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_004392
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_004392
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_004392 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_080759

    UniProtKB/Swiss-Prot: DACH1_HUMAN, Q9UI36
    Function: Transcription factor that is involved in regulation of organogenesis. Seems to be a
    regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in
    myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1
    complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a
    corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase
    inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through
    interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity)

    5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Dach1):

    behavior/neurologicalhomeostasis/metabolismlethality-prenatal/perinatalnervous systemrespiratory system

    3 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0003700 transcription factor activity IEA--
    GO:0005515 protein binding IPI14525983
    About this table

    Pathways & Interactions
    for DACH1

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


     Gene Network CentralTM Interacting Genes and Proteins Network for  DACH1 


    5/26 Interacting proteins for DACH1 (ENSP000003527123 Q9UI361) via UniProtKB, MINT, and/or STRING (see all 26 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NCOR1O753761STRING (score=.974) EBI-347111, EBI-347233
    SIN3AQ96ST31STRING (score=.781) EBI-347111, EBI-347218
    SMAD4Q134851STRING (score=.729) EBI-347111, EBI-347263
    SMAD3P840221EBI-347111, EBI-347161
    SIX1ENSP000002471823STRING (score=.984)
    About this table

    2 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355 regulation of transcription, DNA-dependent IEA--
    GO:0007275 multicellular organismal development IEA--
    About this table

    Drugs & Compounds
    for DACH1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for DACH1

    Transcripts
    for DACH1

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (DACH1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (DACH1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_004392

                  Sigma-Aldrich siRNA for DACH1  
                         Sigma-Aldrich shRNA for DACH1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_004392  NM_080759  NM_080760  

    REFSEQ mRNAs for DACH1 gene (3 alternative transcripts): 

    NM_004392.4   NM_080759.3   NM_080760.3   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_004392  NM_080759  NM_080760  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_004392
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_004392
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_004392 

    Additional cDNA sequence: 

    AF069509.1 AF102546.1 AF356492.1 AJ005670.1 AK001000.1 AL079278.1 BC021219.2 

    19 DOTS entries:

    DT.111486  DT.100025625  DT.120782525  DT.87018230  DT.120782470  DT.100695640  DT.120782500  DT.92423852 
    DT.97864380  DT.120782523  DT.87046178  DT.95129743  DT.95139642  DT.100059951  DT.100695642  DT.100695654 
    DT.120933407  DT.121236364  DT.95223619 

    1 AceView cDNA sequence:

    R74591 

    highest scoring ESTs for DACH1:

    AJ005670 AF069509 AF102546 AF356492 AI003686 AI650353 AK001000 AL079278 AU118230 AW579053 

    Unigene Cluster for DACH1:

    Dachshund homolog 1 (Drosophila)
    Hs.129452  [show with all ESTs]
    Unigene Representative Sequence: NM_080759


    GeneLoc Exon Structure

    6 Ensembl transcripts including schematic representations:
    ENST00000377826  ENST00000400297  ENST00000305425  ENST00000354591  ENST00000313174  ENST00000359684  

    Expression
    for DACH1

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    DACH1 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for DACH1

    1 / 2 / 3

    9 probe-sets matching DACH1 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    44543_at2, 3 U95-B 1 1.00 1.00 0.92 1.17 AI650353 0.80 1.00 0.91 1

    		40312_at2, 3 U95-A 1 1.00 1.00 0.86 0.51 AJ005670 1.00 1.00 1.00 1

    		91228_at2, 3 U95-E 1 0.81 1.00 0.91 0.83 H24419 0.80 1.00 0.91 1

    		205471_s_at2, 3 U133-A 1 1.00 1.00 -- -- AW772082 0.60 1.00 0.82 1

    		205472_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_004392 0.60 1.00 0.82 1

    		228915_at2, 3 U133-B 1 1.00 1.00 -- -- AI650353 0.80 1.00 0.91 1

    		205471_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		205472_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		228915_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  DACH1 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: TAGGACCTAT

    SOURCE GeneReport for Unigene cluster: Hs.129452

    Expression variation in blood from EXPOLDB for DACH1

    UniProtKB/Swiss-Prot: DACH1_HUMAN, Q9UI36
    Tissue specificity: Widely expressed. Isoform 2 is found in brain, heart, kidney, liver, leukocytes
    and spleen. Isoform 3 is found in liver and heart. Isoform 4 is found in spleen

    Orthologs
    for DACH1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for DACH1 gene from 5/7 species (see all 7 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    chimpanzee
    (Pan troglodytes)    		 DACH11   -- dachshund homolog 1 (Drosophila) 99.67(n)
    99.58(a)    		 467281  XM_522679.2  XP_522679.2 
    cow
    (Bos taurus)    		 DACH11   -- dachshund homolog 1 (Drosophila) 94.12(n)
    98.63(a)    		 537184  XM_617340.3  XP_617340.3 
    mouse
    (Mus musculus)    		 Dach11, 5 14 (48.00 cM)5
    		 dachshund 1 (Drosophila)1, 5 91.62(n)1
    97.13(a)1    		 131341  NM_007826.21  NP_031852.11 
     AF0904365  AF0904375  (see all 19)
    chicken
    (Gallus gallus)    		 DACH11   -- dachshund homolog 1 (Drosophila) 86.52(n)
    93.16(a)    		 373935  XM_417018.2  XP_417018.2 
    zebrafish
    (Danio rerio)    		 dachc2   -- dachshund c 75.75(n) 192123  AF427110.1 
    About this table        Species with no ortholog for DACH1

    ENSEMBL Gene Tree for DACH1

    Paralogs
    for DACH1

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for DACH1 gene
    DACH22  

    SNPs/Variants
    for DACH1

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/1903 NCBI SNPs in DACH1 are shown (see all 1903 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 563)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 13 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs73354411,2
    		A,C,F,H70909931(+) TTAGAG/AATAGA 3 -- ng517Minor allele frequency- A:0.11EU EA WA NA 562
    rs13253411,2
    		C,F,H,O71340310(+) GCTAAT/AGTGTT 3 -- ng3113Minor allele frequency- A:0.14MN EU EA WA 1440
    rs105077921,2
    		C,F,H70910093(+) AAAGTC/AACAGG 3 -- ng5111Minor allele frequency- A:0.02NS NA EU EA 550
    rs92852741,2
    		C,F,H70912035(+) TTCTAT/CATACC 3 -- ut31 ese312Minor allele frequency- C:0.08EU EA WA NS NA 660
    rs37595051,2
    		A,C,F71339666(+) TCTCTC/TCTACT 3 -- ng31 trp32Minor allele frequency- T:0.31NA 182
    rs37595061,2
    		A,C71339959(+) TATTTA/GTTTAT 3 -- ng31 tfbs30--------
    rs170882371,2
    		F,H70909700(+) TACTTT/CGCATT 3 -- ng517Minor allele frequency- C:0.01NA EU EA WA 562
    rs95427621,2
    		A,C71340435(+) AAGAAA/CAAAAA 3 -- ng310--------
    rs116202941,2
    		C,H70911355(+) GTGACC/TGTACT 3 -- ut31 ese34Minor allele frequency- T:0.00EU EA WA 416
    rs9811861,2
    		A,C71341243(-) ATAATA/GGTAGT 3 -- ng310--------
    About this table

    HapMap Linkage Disequilibrium images for DACH1 (up to first 250kb)

    Disorders & Mutations
    for DACH1

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 603803

    GeneTests: DACH1
    Anophthalmia/Microphthalmia

    Medical News
    for DACH1

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for DACH1

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/32 PubMed articles for DACH1 gene (see all 32 ):

    Search for DACH1

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing DACH1

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 1602 HGNC: 2663 AceView: DACH1.2 Ensembl:ENSG00000165659 euGenes: HUgn1602
    ECgene: DACH1 H-InvDB: DACH1

    Other Databases showing DACH1

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing DACH1

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    GeneReviewshttp://www.genetests.org/query?gene=DACH1

    Licensable Technologies
    for DACH1

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for DACH1

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for DACH1:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
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      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for DACH1-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for DACH1 Antibodies for DACH1
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for DACH1 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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     Recombinant Proteins
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     Antibodies (DACH1)
     Search OriGene for DACH1
     Search Tocris compounds for DACH1




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Search Novus for antibodies for DACH1

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