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DAB1 Gene

protein-coding GIFtS: 57

GC01M057175

disabled homolog 1 (Drosophila)
(Previous name: disabled (Drosophila) homolog 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
OTTHUMP00000010045 ^²
OTTHUMP00000011753 ^²

Descriptions
disabled (Drosophila) homolog 1 ^¹
disabled homolog 1 ^²
disabled homolog 1 (Drosophila) ^²

External Ids
HGNC: 2661¹
Entrez Gene: 1600²
UniProtKB: O75553³
Ensembl: ENSG00000173406⁷

Search outside databases for aliases for DAB1 gene

Previous GC identifers: GC01M057380 GC01M056378 GC01M056821 GC01M056833

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for DAB1:

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal

cognitive function. In mice, the disabled-1 gene plays a central role in brain development,

directing the migration of cortical neurons past previously formed neurons to reach their proper

layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a

signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in

the developing brain. Alternatively spliced transcript variants of this gene have been reported,

but their full length nature has not been determined. [provided by RefSeq]

UniProtKB/Swiss-Prot: DAB1_HUMAN, O75553

Function: Adapter molecule functioning in neural development. May regulate SIAH1 activity (By

similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DAB1 gene

Entrez Gene cytogenetic band: 1p32-p31 Ensembl cytogenetic band: 1p32.2 HGNC cytogenetic band: 1p32-p31

DAB1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M057175: (about GC identifiers)

Start:	57,233,039 bp from pter
End:	58,488,799 bp from pter
Size:	1,255,761 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000001.9 NT_032977.8

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: DAB1_HUMAN, O75553 (See protein sequence)

Recommended Name: Disabled homolog 1

Size: 588 amino acids; 63775 Da

Subunit: Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By

similarity). Interacts with LRP1

Secondary accessions: A4FU90 Q4LE59 Q5T6M6 Q5T6M9 Q5T835 Q5T836 Q5T837 Q6NWS9 Q6NWT0 Q6NWT1 Q9NYA8

Alternative splicing: 6 isoforms: O75553-1 O75553-2 O75553-3 O75553-4 O75553-5 O75553-6

Post-translational modifications:

Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity).

Also phosphorylated on Ser-524 independently of reelin signaling (By similarity)¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_066566.3

ENSEMBL proteins:

ENSP00000360274 ENSP00000360277 ENSP00000360275 ENSP00000360280 ENSP00000360279 ENSP00000329120

ENSP00000360276 ENSP00000360278

Human Recombinant Proteins

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	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Dab1)
	Human Recombinant Proteins from Abnova (DAB1)

OriGene Purified Recombinant Human Protein: DAB1

Antibodies for DAB1:

	Invitrogen Antibodies for DAB1
	Millipore Mono- and Polyclonal Antibodies for the study of DAB1
	Sigma-Aldrich Antibodies for DAB1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Dab1), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Novus Biologicals Antibodies for DAB1

Assays for DAB1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O75553

ProtoNet protein and cluster: O75553

1 Blocks protein family: IPB006020 Phosphotyrosine interaction domain

UniProtKB/Swiss-Prot: DAB1_HUMAN, O75553

Domain: The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many

tyrosine-phosphorylated proteins

Similarity: Contains 1 PID domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAB1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_021080

Applied Biosystems Silencer® siRNAs for DAB1

Sigma-Aldrich siRNA for DAB1

Sigma-Aldrich shRNA for DAB1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for DAB1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_021080
Myc/DDK tagged cDNA clone in CMV expression vector: NM_021080
untagged cDNA clone in CMV expression vector: NM_021080

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_021080

UniProtKB/Swiss-Prot: DAB1_HUMAN, O75553

Function: Adapter molecule functioning in neural development. May regulate SIAH1 activity (By

murine disabled-1 homolog,expressed in brain and likely involved in brain development

9 MGI mutant phenotypes (inferred from 13 alleles) (MGI details for Dab1):

behavior/neurological	growth/size	lethality-postnatal	lethality-prenatal/perinatal	life span-post-weaning/aging
nervous system	no phenotypic analysis	normal	vision/eye

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for DAB1 (Your Favorite Gene powered by Ingenuity)

Reelin Signaling in Neurons

GeneDecks DAB1 for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for DAB1

5/31 Interacting proteins for DAB1 (ENSP00000360279³ O75553²) via UniProtKB, MINT, and/or STRING (see all 31 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ERBB2	P04626²	MINT-74508
ERBB3	P21860²	MINT-74509
LRP8	ENSP00000303634³	STRING (score=.972)
VLDLR	ENSP00000371532³	STRING (score=.972)
CRKL	ENSP00000346300³	STRING (score=.96)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007275	multicellular organismal development	IEA	--
GO:0007399	nervous system development	IEA	--
GO:0030154	cell differentiation	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for DAB1
4 Novoseek chemical compound relationships for DAB1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
tyrosine	56.63	45	18981215 (3), 15718228 (3), 15883038 (3), 16046028 (2) (see all 22)
phosphotyrosine	56.03	9	16951405 (2), 15632144 (1), 12882964 (1), 12737822 (1) (see all 5)
phosphoinositide	41.69	7	15883038 (2), 15632144 (1), 16046028 (1)
calcium	0.00	1	16148228 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAB1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_021080

Sigma-Aldrich siRNA for DAB1

Sigma-Aldrich shRNA for DAB1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_021080

REFSEQ mRNAs for DAB1 gene:

NM_021080.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_021080

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_021080
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_021080
                                 untagged cDNA clone in CMV expression vector: NM_021080

Additional cDNA sequence:

AB210012.1 AF071062.1 AK055341.1 AK095513.1 AK313144.1 BC067445.1 BC067446.1 BC067447.1

BC112938.1 CR933698.1

9 DOTS entries:

DT.99936978 DT.101976468 DT.213948 DT.100652211 DT.100714297 DT.121416633 DT.121416568 DT.92026769

DT.75157104

24/67 AceView cDNA sequences (see all 67 ):

AK095513 BC067445 NM_021080 AF525763 BE672370 BE503413 BX495838 BC067446

CD673898 AF071062 CD559744 BX955150 BE044577 BG258401 CD559585 CD559743

AF263547 CD559742 BX431127 AA322834 CK130272 BC067447 AW450417 CD559586

highest scoring ESTs for DAB1:

CD559745 AA203232 AF071062 AI990333 AW450417 BC067445 BC067446 BC067447 BE503413 BE672370

Unigene Cluster for DAB1:

Disabled homolog 1 (Drosophila)

Hs.477370 [show with all ESTs]

Unigene Representative Sequence: AB210012

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for DAB1 (see all 6 )

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b	^	6	^	7	^	8a	·	8b	^	9	^	10	^	11	^	12	^	13a	·	13b	^	14	^	15	^	16a	·	16b
SP1:													-						-				-		-
SP2:													-						-				-		-
SP3:													-		-		-		-
SP4:									-		-		-		-		-		-
SP5:																							-		-

About this scheme

ECgene alternative splicing isoforms for DAB1

8 Ensembl transcripts including schematic representations:

ENST00000371230 ENST00000371233 ENST00000371231 ENST00000371236 ENST00000371235 ENST00000332102

ENST00000371232 ENST00000371234

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

DAB1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DAB1

¹ / ² / ³

7 probe-sets matching DAB1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
62114_at²^{, 3}	U95-C	1	0.62	1.00	1.00	1.00	AA203232	0.40	1.00	0.76	1
228329_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AA700440	0.20	1.00	0.72	1
220611_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_021080	0.40	1.00	0.76	1
226020_s_at²	U133-B	2	1.00	0.50	--	--	--	--	--	--	--
228329_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
220611_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
226020_s_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--

GeneDecks DAB1 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.477370

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DAB1 gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DAB1¹	--	disabled homolog 1 (Drosophila)	96.13(n) 98.5(a)	610344 XM_847827.1 XP_852920.1
chimpanzee (Pan troglodytes)	DAB1¹	--	disabled homolog 1 (Drosophila)	99.74(n) 99.81(a)	740508 XM_001155092.1 XP_001155092.1
cow (Bos taurus)	DAB1¹	--	disabled homolog 1 (Drosophila)	95.51(n) 97.5(a)	538818 XM_582976.3 XP_582976.3
rat (Rattus norvegicus)	Dab1¹	--	disabled homolog 1 (Drosophila)	93.15(n) 96.76(a)	266729 NM_153621.1 NP_705885.1
mouse (Mus musculus)	Dab1^{1, 5}	4 (52.70 cM)⁵	disabled homolog 1 (Drosophila)^{1, 5}	92.91(n)¹ 96.58(a)¹	13131¹ NM_177259.3¹ NP_796233.2¹ AI427087⁵ AI894126⁵ (see all 26)

About this table Species with no ortholog for DAB1

ENSEMBL Gene Tree for DAB1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for DAB1 gene

DAB2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/7577 NCBI SNPs in DAB1 are shown (see all 7577 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 2774)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs595056^1,2	A,C,F,H,O	57235914(-)	`ATATCA/GTCATC`	1	--	ng5¹		10		EA NA EU WA	2232
	rs7537039^1,2	A,C,F,H	58489998(+)	`TGCTAG/AGTTTG`	1	--	ng3¹		8		EU EA WA	838
	rs12083827^1,2	C,F,H	57236053(+)	`ATTAAT/CAATTT`	1	--	ng5¹		7		EU EA WA NA	556
	rs1855377^1,2	C,F,H	57374899(-)	`AGGGCG/ATTGTT`	1	I/V	mis¹		5		EU EA WA NA	498
	rs34341631^1,2	C,F	57261827(-)	`GTTTAG/ATTCTG`	1	N/S	mis¹		5		NA EU EA WA	498
--	rs6587805^1,2	A,C	58489339(+)	`ATCTAA/CAAAAT`	1	--	ng3¹		0	--	--	--	--
	rs1538425^1,2	A	58490547(+)	`GCTTGC/TATTAG`	1	--	ng3¹		0	--	--	--	--
--	rs11207179^1,2	A	58488848(+)	`TTCGCA/CACCTA`	1	--	ng3¹		0	--	--	--	--
	rs12404008^1,2	C,H	57253664(+)	`AAGGAC/TGGGAG`	1	P/P	syn¹ ese³		4		EU EA WA	408
	rs932508^1,2	A,C,F,H,O	57437925(+)	`CTACCA/GAAGAT`	1	--	int¹		7		EU EA WA NA	560

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HapMap Linkage Disequilibrium images for DAB1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 603448

1 Novoseek disease relationship for DAB1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
schizophrenia	0.00	1	9861036 (1)

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Human Genome Epidemiology Navigator: DAB1 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/78 PubMed articles for DAB1 gene (see all 78 ):

Cloning of human DAB1 and mapping to chromosome 1p31-p32. (PubMed id 9790777)^{2, 3, 4} Lambert de Rouvroit C. and Goffinet A.M. (1998)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Disabled-1 mRNA and protein expression in developing human cortex. (PubMed id 12581169)^{1, 3} Meyer G....Wahle P. (2003)
DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing. (PubMed id 16951405)^{1, 3} Hoe H.S....Rebeck G.W. (2006)
The gene encoding disabled-1 (DAB1), the intracellular adaptor of the Reelin pathway, reveals unusual complexity in human and mouse. (PubMed id 12446734)^{1, 3} Bar I....Goffinet A.M. (2003)
Disabled1 regulates the intracellular trafficking of reelin receptors. (PubMed id 15718228)^{1, 3} Morimura T....Mikoshiba K. (2005)
Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing. (PubMed id 18089558)^{1, 3} Hoe H.S....Rebeck G.W. (2008)
Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development. (PubMed id 17974915)^{1, 3} Feng L....Cooper J.A. (2007)
Disabled-1 is a large common fragile site gene, inactivated in multiple cancers. (PubMed id 18008369)^{1, 3} McAvoy S....Smith D.I. (2008)
The reelin pathway components disabled-1 and p35 in gangliogliomas--a mutation and expression analysis. (PubMed id 15175076)^{1, 3} Kam R....Becker A.J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 1600	HGNC: 2661	AceView: DAB1	Ensembl:ENSG00000173406	euGenes: HUgn1600
ECgene: DAB1	H-InvDB: DAB1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for DAB1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for DAB1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DAB1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DAB1		Antibodies for DAB1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DAB1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for DAB1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for DAB1

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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DAB1 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for DAB1

Summaries
for DAB1

Genomic Location
for DAB1

Proteins
for DAB1

Protein Domains/
Families
for DAB1

Gene Function
for DAB1

Pathways & Interactions
for DAB1

Drugs & Compounds
for DAB1

Transcripts
for DAB1

Expression
for DAB1

Orthologs
for DAB1

Paralogs
for DAB1

SNPs/Variants
for DAB1

Disorders & Mutations
for DAB1

Medical News
for DAB1

Publications
for DAB1

Search for DAB1

Genome Databases showing DAB1

Other Databases showing DAB1

Specialized Databases showing DAB1

Licensable Technologies
for DAB1

Services
for DAB1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DAB1 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor DAB1

Summariesfor DAB1

Genomic Locationfor DAB1

Proteinsfor DAB1

Protein Domains/Familiesfor DAB1

Gene Functionfor DAB1

Pathways & Interactionsfor DAB1

Drugs & Compoundsfor DAB1

Transcriptsfor DAB1

Expression for DAB1

Orthologsfor DAB1

Paralogsfor DAB1

SNPs/Variantsfor DAB1

Disorders & Mutationsfor DAB1

Medical Newsfor DAB1

Publicationsfor DAB1

Search for DAB1

Genome Databases showing DAB1

Other Databases showing DAB1

Specialized Databases showing DAB1

Licensable Technologiesfor DAB1

Servicesfor DAB1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DAB1

Summaries
for DAB1

Genomic Location
for DAB1

Proteins
for DAB1

Protein Domains/
Families
for DAB1

Gene Function
for DAB1

Pathways & Interactions
for DAB1

Drugs & Compounds
for DAB1

Transcripts
for DAB1

Expression
for DAB1

Orthologs
for DAB1

Paralogs
for DAB1

SNPs/Variants
for DAB1

Disorders & Mutations
for DAB1

Medical News
for DAB1

Publications
for DAB1

Licensable Technologies
for DAB1

Services
for DAB1