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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

DAAM2 Gene

protein-coding   GIFtS: 59
GCID: GC06P039807

Dishevelled Associated Activator Of Morphogenesis 2

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Dishevelled Associated Activator Of Morphogenesis 21 2
KIAA03813 5
dJ90A20A.12
Disheveled-Associated Activator Of Morphogenesis 22
Dishevelled-Associated Activator Of Morphogenesis 22

External Ids:    HGNC: 181431   Entrez Gene: 235002   Ensembl: ENSG000001461227   OMIM: 6066275   UniProtKB: Q86T653   

Export aliases for DAAM2 gene to outside databases

Previous GC identifers: GC06P039837 GC06P039868 GC06P039535


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for DAAM2 Gene: 
DAAM2 (dishevelled associated activator of morphogenesis 2) is a protein-coding gene. Diseases associated with DAAM2 include chondrosarcoma, and among its related super-pathways are Wnt Signaling Pathway. GO annotations related to this gene include Rho GTPase binding and actin binding. An important paralog of this gene is DAAM1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the DAAM2 gene promoter:
         GR   AREB6   AML1a   GR-beta   Pax-2   GR-alpha   Pax-2a   ZIC2/Zic2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidDAAM2 promoter sequence
   Search SABiosciences Chromatin IP Primers for DAAM2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat DAAM2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.2   Ensembl cytogenetic band:  6p21.2   HGNC cytogenetic band: 6p21.1

DAAM2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
DAAM2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P039807:  view genomic region     (about GC identifiers)

Start:
39,760,142 bp from pter      End:
39,872,653 bp from pter
Size:
112,512 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: DAAM2_HUMAN, Q86T65 (See protein sequence)
Recommended Name: Disheveled-associated activator of morphogenesis 2  
Size: 1068 amino acids; 123499 Da
Sequence caution: Sequence=BAA20835.2; Type=Erroneous initiation;
Secondary accessions: G5EA45 Q5T4T8 Q5T4U0 Q9NQI5 Q9Y4G0
Alternative splicing: 2 isoforms:  Q86T65-3   Q86T65-4   

Explore the universe of human proteins at neXtProt for DAAM2: NX_Q86T65

Explore proteomics data for DAAM2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q86T65

  • DAAM2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    DAAM2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001188356.1  NP_056160.2  

    ENSEMBL proteins: 
     ENSP00000274867   ENSP00000381876   ENSP00000437808   ENSP00000384637  

    Human Recombinant Protein Products for DAAM2: 
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    Cloud-Clone Corp. Proteins for DAAM2 


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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/8 InterPro protein domains (see all 8):
     IPR010473 Drf_GTPase-bd
     IPR010472 Drf_FH3
     IPR011989 ARM-like
     IPR015425 FH2_actin-bd
     IPR014767 Diaphanous_autoregulatory

    Graphical View of Domain Structure for InterPro Entry Q86T65

    ProtoNet protein and cluster: Q86T65

    2 Blocks protein domains:
    IPB003104 Actin-binding FH2
    IPB010472 Diaphanous FH3


    UniProtKB/Swiss-Prot: DAAM2_HUMAN, Q86T65
    Domain: The DAD domain regulates activation via by an autoinhibitory interaction with the GBD/FH3 domain. This
    autoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2
    domain to then nucleate and elongate nonbranched actin filaments (By similarity)
    Similarity: Belongs to the formin homology family
    Similarity: Contains 1 DAD (diaphanous autoregulatory) domain
    Similarity: Contains 1 FH1 (formin homology 1) domain
    Similarity: Contains 1 FH2 (formin homology 2) domain
    Similarity: Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain


    DAAM2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0005488binding ----
    GO:0017048Rho GTPase binding IEA--
         
    DAAM2 for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Daam2):
     craniofacial  growth/size  immune system  skeleton 

    DAAM2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for DAAM2 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for DAAM2 
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    SwitchGear 3'UTR luciferase reporter plasmidDAAM2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for DAAM2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Wnt signaling pathway
    Wnt signaling pathway0.40
    2WNT Signaling
    WNT Signaling

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for DAAM2
        WNT Signaling


    1         Kegg Pathway  (Kegg details for DAAM2):
        Wnt signaling pathway


    DAAM2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for DAAM2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/6 Interacting proteins for DAAM2 (Q86T653 ENSP000003818764) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CAMKK2Q96RR43I2D: score=1 
    MDM2Q009873I2D: score=1 
    DVL1ENSP000003681694STRING: ENSP00000368169
    DVL2ENSP000000053404STRING: ENSP00000005340
    DVL3ENSP000003160544STRING: ENSP00000316054
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016043cellular component organization ----
    GO:0030036actin cytoskeleton organization IEA--

    DAAM2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for DAAM2

    Search CenterWatch for drugs/clinical trials and news about DAAM2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for DAAM2 gene (2 alternative transcripts): 
    NM_001201427.1  NM_015345.3  

    Unigene Cluster for DAAM2:

    Dishevelled associated activator of morphogenesis 2
    Hs.357128  [show with all ESTs]
    Unigene Representative Sequence: NM_015345
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000274867(uc010jxc.3 uc003oow.3) ENST00000398904 ENST00000475489
    ENST00000494405 ENST00000491083 ENST00000496787 ENST00000538976(uc003oox.3)
    ENST00000405961(uc003ooy.4)
    miRNA
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    8/44 QIAGEN miScript miRNA Assays for microRNAs that regulate DAAM2 (see all 44):
    hsa-miR-4254 hsa-miR-1197 hsa-miR-29a hsa-miR-124 hsa-miR-1184 hsa-miR-4325 hsa-miR-133a hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmidDAAM2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat DAAM2
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for DAAM2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat DAAM2
    Sirion Biotech Customized lentivirus for stable overexpression of DAAM2 
                         Customized lentivirus expression plasmids for stable overexpression of DAAM2 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat DAAM2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat DAAM2

    Additional mRNA sequence: 

    AB002379.2 AK310111.1 AK310941.1 AL833083.2 BC014275.2 BC047555.1 BC078153.1 BC128388.1 

    14 DOTS entries:

    DT.101983952  DT.91744099  DT.100048626  DT.95174580  DT.91715233  DT.100694454  DT.100000228  DT.100025782 
    DT.100638231  DT.91712887  DT.95174584  DT.97843321  DT.121366769  DT.91814233 

    24/155 AceView cDNA sequences (see all 155):

    CB156369 AI695717 BM702131 AA642518 AI572246 BQ672979 BC014275 BM664836 
    BG761505 T33927 BX509451 NM_015345 BF594052 AI088917 AI366006 BF197174 
    AW513907 BF513244 BM974490 Z40552 CD674696 BE383989 AW027237 CF130640 

    GeneLoc Exon Structure

    5/17 Alternative Splicing Database (ASD) splice patterns (SP) for DAAM2 (see all 17)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^
    SP1:              -     -     -     -     -     -                       -     -     -                                                                           
    SP2:                    -     -     -     -     -                       -     -     -                                                                           
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 19a · 19b ^ 20 ^ 21 ^ 22a · 22b ^ 23a · 23b ^ 24 ^ 25a · 25b ^ 26a · 26b ^ 27a · 27b · 27c ^ 28 ^ 29 ^ 30 ^ 31
    SP1:                                                                                                                        
    SP2:                                                                                                                        
    SP3:                                                        -                                                               
    SP4:                                                        -                                                               
    SP5:                                                        -                                                               


    ECgene alternative splicing isoforms for DAAM2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    DAAM2 expression in normal human tissues (normalized intensities)      DAAM2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCTCCCCAC
    DAAM2 Expression
    About this image


    DAAM2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Myelinating Oligodendrocyte Cells Forebrain White Matter
             Thalamus
             Human Brain Vascular Pericyte (HBVP)   
             Olfactory Bulb   
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
             spinal cord/lateral wall/ventricular layer   
     
     Eye (Sensory Organs)    fully expand to see all 3 entries
             Retina
             retinal progenitor cell e12.5   
     
     Primitive Streak (Early Embryonic Tissues)    fully expand to see all 2 entries
             Notochord Cells Notochord
             Notochord
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             Allantois Cells Allantois
             Allantois

    See DAAM2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for DAAM2

    SOURCE GeneReport for Unigene cluster: Hs.357128

    UniProtKB/Swiss-Prot: DAAM2_HUMAN, Q86T65
    Tissue specificity: Expressed in most tissues examined

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for DAAM2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for DAAM2 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Daam21 , 5 dishevelled associated activator of morphogenesis 21, 5 86.68(n)1
    92.03(a)1
      17 (25.50 cM)5
    764411  NM_001008231.21  NP_001008232.21 
     494560225 
    chicken
    (Gallus gallus)
    Aves DAAM21 dishevelled associated activator of morphogenesis 2 75.56(n)
    82.42(a)
      421422  XM_419476.3  XP_419476.3 
    lizard
    (Anolis carolinensis)
    Reptilia DAAM26
    Uncharacterized protein
    80(a)
    1 ↔ 1
    1(247088005-247210475)
    zebrafish
    (Danio rerio)
    Actinopterygii daam21 dishevelled associated activator of morphogenesis 2 70.65(n)
    73.93(a)
      798465  XM_001338872.4  XP_001338908.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta EG:114D9.23 actin binding 44(a)   1F1   --
    worm
    (Caenorhabditis elegans)
    Secernentea F56E10.23   -- 33(a)   V(65432-70834)   --


    ENSEMBL Gene Tree for DAAM2 (if available)
    TreeFam Gene Tree for DAAM2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for DAAM2 gene
    DAAM12  DIAPH12  FMNL32  FHDC12  FMNL12  INF22  FMNL22  GRID2IP2  
    FMN12  DIAPH22  FMN22  DIAPH32  
    5 SIMAP similar genes for DAAM2 using alignment to 3 protein entries:     DAAM2_HUMAN (see all proteins):
    DAAM1    DIAPH1    DKFZp762B245    DIAPH3    DIAPH2

    DAAM2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2125 SNPs in DAAM2 are shown (see all 2125)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0558064
    ----see VAR_0558062 R H mis40--------
    rs3026321,2
    C,F,H--39758306(-) gggagG/Accgag 1 -- us2k13Minor allele frequency- A:0.40NA CSA 5
    rs93946291,2
    C,F,H--39758362(+) TGATCT/CTCTCT 1 -- us2k121Minor allele frequency- C:0.31NS EA NA CSA WA 2346
    rs93808951,2
    C,F,H--39758431(+) ACTTGG/ATCTCA 1 -- us2k121Minor allele frequency- A:0.27NS EA NA CSA WA 2344
    rs1859652451,2
    --39758437(+) TCTCAC/TAGCAA 1 -- us2k10--------
    rs728556041,2
    C,F--39758446(+) AATTGT/CGAGCT 1 -- us2k11Minor allele frequency- C:0.08WA 118
    rs93808961,2
    C,F--39758515(+) CAAGGG/TAGAAT 1 -- us2k18Minor allele frequency- T:0.36NA CSA EA 252
    rs768924701,2
    F--39758546(+) GAAACC/TTATTT 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1408231531,2
    --39758729(+) CTACCA/GAGAGG 1 -- us2k10--------
    rs1497577571,2
    --39758732(+) CCGAGA/TGGCCC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for DAAM2 (39760142 - 39872653 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for DAAM2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2731956CNV Deletion23290073
    nsv512877CNV Insertion21212237
    nsv509130CNV Insertion20534489
    nsv462921CNV Loss19166990

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606627    OMIM disorders: --

    2 diseases for DAAM2:    About MalaCards
    chondrosarcoma    

    1 disease from the University of Copenhagen DISEASES database for DAAM2:
    Chondrosarcoma

    DAAM2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): DAAM2
    Human Genome Epidemiology (HuGE) Navigator: DAAM2 (1 document)

    Export disorders for DAAM2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for DAAM2 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with DAAM2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human DAAM2 gene in silico. (PubMed id 12632087)1, 3, 9 Katoh M. and Katoh M. (2003)
    2. Genome-wide association study identifies five loci as sociated with lung function. (PubMed id 20010834)1, 4 Repapi E....Rudnicka A.R. (2010)
    3. Wnt antagonist gene polymorphisms and renal cancer. (PubMed id 19562778)1, 4 Hirata H....Dahiya R. (2009)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. (PubMed id 11779461)1, 3 Habas R.... He X. (2001)
    6. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2 Nagase T.... Ohara O. (1997)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Sequence identification of 2,375 human brain genes. (PubMed id 1538749)1 Adams M.D.... Venter J.C. (1992)
    10. WNT/PCP signaling pathway and human cancer (review). (PubMed id 16273260)9 Katoh M. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23500 HGNC: 18143 AceView: DAAM2 Ensembl:ENSG00000146122 euGenes: HUgn23500
    ECgene: DAAM2 Kegg: 23500 H-InvDB: DAAM2

    (According to HUGE)
    About This Section
    HUGE: KIAA0381

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for DAAM2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for DAAM2 gene:
    Search GeneIP for patents involving DAAM2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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