V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

DAAM1 Gene

protein-coding GIFtS: 63

GC14P058725

dishevelled associated activator of morphogenesis 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FLJ41657 ^²
KIAA0666 ^¹, ², ³, ⁵
OTTHUMP00000179033 ^²

Descriptions
dishevelled associated activator of morphogenesis 1 ^²
dishevelled-associated activator of morphogenesis 1 ^²

External Ids
HGNC: 18142¹
Entrez Gene: 23002²
UniProtKB: Q9Y4D1³
Ensembl: ENSG00000100592⁷

Search outside databases for aliases for DAAM1 gene

Previous GC identifers: GC14P056979 GC14P053451 GC14P057645

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for DAAM1:

Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the

reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin

homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains

and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling

activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell

polarity and movement during development. Activation requires Dvl-Rho complex formation, an

assembly mediated by this gene product, which is thought to function as a scaffolding protein.

Evidence of alternative splicing has been observed for this gene but the full-length nature of

these variants has not been determined. [provided by RefSeq]

UniProtKB/Swiss-Prot: DAAM1_HUMAN, Q9Y4D1

Function: Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation.

May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP

formation. Can direct nucleation and elongation of new actin filaments

Gene Wiki entry for DAAM1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the DAAM1 gene

Entrez Gene cytogenetic band: 14q23.1 Ensembl cytogenetic band: 14q23.1 HGNC cytogenetic band: 14q22.3

DAAM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14P058725: (about GC identifiers)

Start:	58,725,152 bp from pter
End:	58,907,876 bp from pter
Size:	182,725 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000014.7 NT_026437.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: DAAM1_HUMAN, Q9Y4D1 (See protein sequence)

Recommended Name: Disheveled-associated activator of morphogenesis 1

Size: 1078 amino acids; 123473 Da

Subunit: Homodimer. Interacts with CIP4, FNBP1 and FNBP1L. Interacts with the SH3 domains of Abl,

BTK, endophilin, spectrin and SRC. Binds specifically to GTP-bound CDC42 and RHOA

Subcellular location: Cytoplasm. Note=Perinuclear

PDB structure from and Proteopedia :

2J1D (3D)

2Z6E (3D)

Secondary accessions: Q86U34 Q8N1Z8 Q8TB39

Alternative splicing: 3 isoforms: Q9Y4D1-1 Q9Y4D1-2 Q9Y4D1-3

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_055807.1

ENSEMBL proteins:

ENSP00000247170 ENSP00000351287 ENSP00000354162 ENSP00000378557

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (DAAM1)
	Human Recombinant Proteins from Abnova (DAAM1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--

About this table

Antibodies for DAAM1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for DAAM1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (DAAM1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (DAAM1)
	Novus Biologicals Antibodies for DAAM1

Assays for DAAM1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9Y4D1

ProtoNet protein and cluster: Q9Y4D1

2 Blocks protein families:

IPB003104 Actin-binding FH2

IPB010472 Diaphanous FH3

UniProtKB/Swiss-Prot: DAAM1_HUMAN, Q9Y4D1

Domain: The C-terminal DAD domain may participate in intramolecular interactions with the

N-terminus

Similarity: Belongs to the formin homology family

Similarity: Contains 1 DAD (diaphanous autoregulatory) domain

Similarity: Contains 1 FH1 (formin homology 1) domain

Similarity: Contains 1 FH2 (formin homology 2) domain

Similarity: Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAAM1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DAAM1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014992

Applied Biosystems Silencer® siRNAs for DAAM1

Sigma-Aldrich siRNA for DAAM1

Sigma-Aldrich shRNA for DAAM1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for DAAM1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_014992
Myc/DDK tagged cDNA clone in CMV expression vector: NM_014992
untagged cDNA clone in CMV expression vector: NM_014992

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_014992

UniProtKB/Swiss-Prot: DAAM1_HUMAN, Q9Y4D1

Function: Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation.

May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP

formation. Can direct nucleation and elongation of new actin filaments

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003779	actin binding	IEA	--
GO:0017048	Rho GTPase binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for DAAM1

5/31 Interacting proteins for DAAM1 (ENSP00000247170³ Q9Y4D1²) via UniProtKB, MINT, and/or STRING (see all 31 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TRIP10	Q15642²	STRING (score=.917) MINT-7146205 MINT-7146069
ARHGEF19	Q8IW93²	STRING (score=.836) MINT-6504351
CDC42P2	P60953²	STRING (score=.864) MINT-7146238
FNBP1	Q96RU3²	STRING (score=.718) MINT-7146160
PRPF40A	O75400²	STRING (score=.785) MINT-61858

About this table

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016043	cellular component organization	IEA	--
GO:0030036	actin cytoskeleton organization	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for DAAM1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (DAAM1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (DAAM1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014992

Sigma-Aldrich siRNA for DAAM1

Sigma-Aldrich shRNA for DAAM1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_014992

REFSEQ mRNAs for DAAM1 gene:

NM_014992.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_014992

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_014992
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_014992
                                 untagged cDNA clone in CMV expression vector: NM_014992

Additional cDNA sequence:

AB014566.1 AK021890.1 AK023892.1 AK093813.1 AK123651.1 AK291790.1 BC024781.1 BC038428.1

BC064999.1 BX247986.1 BX648383.1 CR609221.1

10 DOTS entries:

DT.452909 DT.97839555 DT.101978875 DT.100669228 DT.91955185 DT.70103627 DT.100692624 DT.100795585

DT.316327 DT.120730495

24/260 AceView cDNA sequences (see all 260 ):

AW090763 BI755288 BM721944 AI659015 AA487359 BE884438 BQ026874 AW238502

AL043290 AA487338 AA278828 AI292318 AI280147 AA731456 AA677452 AI452880

AA278826 AA731830 AA889970 AI688825 AB014566 F08952 BC064999 BE818918

highest scoring ESTs for DAAM1:

AB014566 AA043108 AA278826 AA278828 AA487243 AA609681 AA625524 AA731456 AA731830 AA772712

Unigene Cluster for DAAM1:

Dishevelled associated activator of morphogenesis 1

Hs.654934 [show with all ESTs]

Unigene Representative Sequence: NM_014992

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for DAAM1 (see all 8 )

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	^	2a	·	2b	^	3a	·	3b	^	4	^	5a	·	5b	·	5c	^	6	^	7	^	8	^	9	^	10	^	11a	·	11b	^	12	^	13	^	14	^	15	^	16	^	17	^
SP1:									-				-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-
SP2:
SP3:
SP4:
SP5:									-								-

ExUns:	18a	·	18b	^	19	^	20a	·	20b	^	21a	·	21b	^	22	^	23	^	24a	·	24b	^	25	^	26
SP1:																			-
SP2:									-		-						-		-
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for DAAM1

4 Ensembl transcripts including schematic representations:

ENST00000351081 ENST00000358498 ENST00000360909 ENST00000395125

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

DAAM1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for DAAM1

¹ / ² / ³

11 probe-sets matching DAAM1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
33753_at²^{, 3}	U95-A	1	1.00	1.00	0.85	0.85	AB014566	1.00	1.00	1.00	1
49389_at²^{, 3}	U95-B	1	0.94	1.00	0.70	1.28	AI262504	0.40	1.00	0.76	1
67510_at²^{, 3}	U95-E	1	0.50	1.00	0.46	0.88	AL043148	0.20	1.00	0.72	1
226666_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BG434703	0.40	1.00	0.76	1
216060_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AK021890	0.60	1.00	0.82	1
244062_at²^{, 3}	U133-B	1	0.64	1.00	--	--	AL043148	0.20	1.00	0.72	1
232552_at*²^{, 3}	U133-B	1	1.00	1.00	--	--	AU159022	0.20	1.00	0.72	1
226666_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
216060_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
244062_at²	U133Plus2	1	0.64	1.00	--	--	--	--	--	--	--
232552_at*²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CTTTTTTAAA

SOURCE GeneReport for Unigene cluster: Hs.654934
Expression variation in blood from EXPOLDB for DAAM1
UniProtKB/Swiss-Prot: DAAM1_HUMAN, Q9Y4D1
Tissue specificity: Expressed in all tissues examined

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for DAAM1 gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	DAAM1¹	--	dishevelled associated activator of morphogenesis 1	92.7(n) 97.57(a)	490714 XM_859929.1 XP_865022.1
cow (Bos taurus)	DAAM1¹	--	dishevelled associated activator of morphogenesis 1	92.89(n) 98.61(a)	513742 XM_591485.3 XP_591485.3
rat (Rattus norvegicus)	Daam1¹	--	dishevelled associated activator of morphogenesis 1	88.99(n) 97.12(a)	314212 XM_234275.4 XP_234275.4
mouse (Mus musculus)	Daam1^{1, 5}	12⁵	dishevelled associated activator of morphogenesis 1^{1, 5}	89.11(n)¹ 97.21(a)¹	208846¹ NM_026102.2¹ NP_080378.2¹ AI503486⁵ AI838037⁵ (see all 25)
chicken (Gallus gallus)	DAAM1¹	--	dishevelled associated activator of morphogenesis 1	78.69(n) 89.26(a)	423532 XM_421429.2 XP_421429.2

About this table Species with no ortholog for DAAM1

ENSEMBL Gene Tree for DAAM1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for DAAM1 gene

DAAM2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1023 NCBI SNPs in DAAM1 are shown (see all 1023 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 414)

AB	SNP ID	Valid	Chr 14 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1438521^1,2	A,C,F,H,O	58723553(-)	`CTTCCA/GTTTCA`	1	--	ng5¹		12		NS NA EU EA WA	654
	rs17833769^1,2	C,F,H	58725214(+)	`GCCGCC/ATTTCC`	1	--	ut5¹		8		NA EA EU WA	618
	rs958043^1,2	C,F,H	58723953(+)	`TACATT/GTACAA`	1	--	ng5¹ tfbs³		4		EU EA WA	418
	rs1252908^1,2	C,F,O	58724446(-)	`CGGAGG/CTTGTC`	1	--	ng5¹		4		MN NA	314
	rs1438520^1,2	F,H	58723563(-)	`TCAGCT/AACTTC`	1	--	ng5¹		2		EU WA	218
--	rs3742647^1,2	A,C	58905725(-)	`GCTTTG/TTTTGT`	1	--	ut3¹		0	--	--	--	--
	rs4901906^1,2	H	58724402(+)	`GGTTGC/TGGCGA`	1	--	ng5¹		4		EU EA WA	420
--	rs3842328^1,2	C	58906105(-)	`TCTTT-/AAAAAA`	1	--	ut3¹		0	--	--	--	--
	rs941884^1,2	A,C,F,H	58866988(+)	`CTACAG/ACAGAA`	1	Q/Q	syn¹ ese³		7		NA EU EA WA	534
	rs8022614^1,2	A,C,F,H	58859480(+)	`ATAAAG/AGCGTT`	1	K/K	syn¹ ese³		8		NA EU EA WA	626

About this table

HapMap Linkage Disequilibrium images for DAAM1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 606626

1 PharmGKB disease relationship for DAAM1 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/17 PubMed articles for DAAM1 gene (see all 17 ):

Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. (PubMed id 11779461)^{2, 3, 4} Habas R.... He X. (2001)
Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly. (PubMed id 17482208)^{1, 3, 4} Lu J....Eck M.J. (2007)
Mechanism of activation of the Formin protein Daam1. (PubMed id 18162551)^{2, 3} Liu W....Habas R. (2008)
The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics. (PubMed id 16630611)^{3, 4} Aspenstroem P.... Johansson A.-S. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)^{3, 4} Heilig R.... Weissenbach J. (2003)
Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)^{3, 4} Ishikawa K....Ohara O. (1998)
Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets. (PubMed id 18218625)^{1, 3} Higashi T....Horiuchi H. (2008)
Crystal structure of human DAAM1 formin homology 2 domain. (PubMed id 17986009)³ Yamashita M....Nureki O. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 23002	HGNC: 18142	AceView: DAAM1	Ensembl:ENSG00000100592	euGenes: HUgn23002
ECgene: DAAM1	H-InvDB: DAAM1

(According to HUGE)
About This Section

HUGE: KIAA0666

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for DAAM1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for DAAM1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for DAAM1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for DAAM1		Antibodies for DAAM1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for DAAM1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (DAAM1)
	Antibodies (DAAM1)
	Chimera RNAi (DAAM1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (DAAM1)
	Antibodies (DAAM1)

Search OriGene for DAAM1

Search Tocris compounds for DAAM1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for DAAM1

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
DAAM1 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

DAAM1 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for DAAM1

Summaries
for DAAM1

Genomic Location
for DAAM1

Proteins
for DAAM1

Protein Domains/
Families
for DAAM1

Gene Function
for DAAM1

Pathways & Interactions
for DAAM1

Drugs & Compounds
for DAAM1

Transcripts
for DAAM1

Expression
for DAAM1

Orthologs
for DAAM1

Paralogs
for DAAM1

SNPs/Variants
for DAAM1

Disorders & Mutations
for DAAM1

Medical News
for DAAM1

Publications
for DAAM1

Search for DAAM1

Genome Databases showing DAAM1

Other Databases showing DAAM1

Specialized Databases showing DAAM1

Licensable Technologies
for DAAM1

Services
for DAAM1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DAAM1 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor DAAM1

Summariesfor DAAM1

Genomic Locationfor DAAM1

Proteinsfor DAAM1

Protein Domains/Familiesfor DAAM1

Gene Functionfor DAAM1

Pathways & Interactionsfor DAAM1

Drugs & Compoundsfor DAAM1

Transcriptsfor DAAM1

Expression for DAAM1

Orthologsfor DAAM1

Paralogsfor DAAM1

SNPs/Variantsfor DAAM1

Disorders & Mutationsfor DAAM1

Medical Newsfor DAAM1

Publicationsfor DAAM1

Search for DAAM1

Genome Databases showing DAAM1

Other Databases showing DAAM1

Specialized Databases showing DAAM1

Licensable Technologiesfor DAAM1

Servicesfor DAAM1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for DAAM1

Summaries
for DAAM1

Genomic Location
for DAAM1

Proteins
for DAAM1

Protein Domains/
Families
for DAAM1

Gene Function
for DAAM1

Pathways & Interactions
for DAAM1

Drugs & Compounds
for DAAM1

Transcripts
for DAAM1

Expression
for DAAM1

Orthologs
for DAAM1

Paralogs
for DAAM1

SNPs/Variants
for DAAM1

Disorders & Mutations
for DAAM1

Medical News
for DAAM1

Publications
for DAAM1

Licensable Technologies
for DAAM1

Services
for DAAM1