CDC16 Gene
protein-coding GIFtS: 61
GCID: GC13P115000
|
|
cell division cycle 16(Previous names: CDC16 (cell division cycle 16, S. cerevisiae, homolog),...)
| |
Aliases
for CDC16 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cell Division Cycle 161 2 | | CDC16 (Cell Division Cycle 16, S. Cerevisiae, Homolog)1 | | ANAPC61 2 3 | | CDC16 Cell Division Cycle 16 Homolog (S. Cerevisiae)1 | | APC61 2 3 | | Cell Division Cycle 16 Homolog (S. Cerevisiae)1 | | CUT91 2 | | Anaphase-Promoting Complex, Subunit 62 | | Anaphase-Promoting Complex Subunit 62 3 | | Cell Division Cycle 16 Homolog2 | | Cyclosome Subunit 62 3 | | Cell Division Cycle Protein 16 Homolog2 | | CDC16Hs2 3 | | CDC16 Homolog3 |
Export aliases for CDC16 gene to outside databasesPrevious GC identifers: GC13P113361 GC13P111188 GC13P114022 GC13P112918 GC13P114018 GC13P095262 |
Summaries
for CDC16 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CDC16:
This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as aprotein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Eachcomponent protein of the APC complex is highly conserved among eukaryotic organisms. This protein and two other APCcomplex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved inprotein-protein interaction. Multiple alternatively spliced variants, encoding the same protein, have been identified.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CDC16_HUMAN, Q13042Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligasethat controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediatingubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linkedpolyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains
Gene Wiki entry for CDC16
|
Genomic Views
for CDC16 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024498.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CDC16 gene promoter:
Max1 Sox5 ATF-2 Nkx5-1 S8 HSF2 Sox9 TGIF ATF c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for CDC16
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDC16 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q34 Ensembl cytogenetic band: 13q34 HGNC cytogenetic band: 13q34CDC16 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13P115000: view genomic region
(about GC identifiers)
Start:
|
115,000,362 bp from pter |
End:
|
115,038,198 bp from pter |
Size:
|
37,837 bases |
Orientation:
|
plus strand |
|
Proteins
for CDC16 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CDC16_HUMAN, Q13042 (See
protein sequence)Recommended Name: Cell division cycle protein 16 homolog Size: 620 amino acids; 71656 Da
Subunit: The APC/C is composed of at least 12 subunits. Interacts with PPP5C and CDC20
Subcellular location: Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes withCDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle
1 PDB 3D structure from  and Proteopedia  for CDC16:3HYM (3D)
Secondary accessions: A2A365 Q5T8C8 Q96AE6 Q9Y564Alternative splicing: 3 isoforms: Q13042-1 Q13042-2 Q13042-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CDC16: NX_Q13042
Post-translational modifications:
Phosphorylated. Phosphorylation on Ser-560 occurs specifically during mitosis1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13042
CDC16 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001072113.1 NP_003894.3
ENSEMBL proteins: ENSP00000348554 ENSP00000364459 ENSP00000252457 ENSP00000364457 ENSP00000252458 ENSP00000353549 ENSP00000364461 Reactome Protein details: Q13042
Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
CDC16 for ontologies About GeneDecksing
CDC16 Antibody Products:
Assay Products for CDC16: |
Protein
Domains /
Families
for CDC16 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CDC16 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13042ProtoNet protein and cluster: Q13042 UniProtKB/Swiss-Prot: CDC16_HUMAN, Q13042Similarity: Belongs to the APC6/CDC16 familySimilarity: Contains 7 TPR repeats |
Function
for CDC16 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CDC16_HUMAN, Q13042Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligasethat controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediatingubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linkedpolyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDC16 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDC16 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CDC16 (NM_003903) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDC16 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDC16 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDC16 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- |
CDC16 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for CDC16:
|
Pathways & Interactions
for CDC16 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/24 super-pathways (see all 24) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ubiquitinated Orc1 is degraded by the proteasome | | | 2 | APC-Cdc20 mediated degradation of Nek2A | | | 3 | M Phase | | | 4 | Antigen processing: Ubiquitination & Proteasome degradation | | | 5 | Cell cycle_Spindle assembly and chromosome separation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/9 EMD Millipore Pathways for CDC16 (see all 9)
5/6 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CDC16 (see all 6)
2 
Cell Signaling Technology (CST) Pathways for CDC16
5/7  GeneGo (Thomson Reuters) Pathways for CDC16 (see all 7)
1  BioSystems Pathway for CDC16
5/36 
Reactome Pathways for CDC16 (see all 36)
4 
Kegg Pathways (Kegg details for CDC16):
UniProtKB/Swiss-Prot: CDC16_HUMAN, Q13042Pathway: Protein modification; protein ubiquitination
CDC16 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CDC16
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/904 Interacting proteins for CDC16 (Q130421, 2, 3 ENSP000003485544) via UniProtKB, MINT, STRING, and/or I2D (see all 904)
About this table
Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12): About this table
CDC16 for ontologies About GeneDecksing
|
Drugs & Compounds
for CDC16 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CDC16
Search CenterWatch for drugs/clinical trials and news about CDC16
|
Transcripts
for CDC16 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CDC16 gene (2 alternative transcripts): NM_001078645.1 NM_003903.3 Unigene Cluster for CDC16: Cell division cycle 16 homolog (S. cerevisiae) Hs.374127 [show with all ESTs]Unigene Representative Sequence: AK09508211 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000356221 ENST00000375310 ENST00000494766(uc010tkm.1) ENST00000252457
ENST00000375308 ENST00000252458 ENST00000484907 ENST00000494581 ENST00000461716
ENST00000360383(uc001vuk.1 uc001vul.1 uc001vum.1 uc001vun.1)
ENST00000375312(uc001vuo.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDC16 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDC16 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CDC16 (NM_003903) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDC16 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDC16 |
Additional cDNA sequence: AF164598.1 AK095082.1 AK296424.1 AK315302.1 BC010875.2 BC017244.1 BC050575.1 U18291.1 24 DOTS entries: DT.91770418 DT.100044735 DT.100821770 DT.95161341 DT.307591 DT.120769459 DT.91770435 DT.100821762 DT.91770417 DT.91770423 DT.97806699 DT.120769485 DT.100821763 DT.91866246 DT.100044733 DT.100811603 DT.120769506 DT.92023836 DT.95161343 DT.97796741 DT.99960725 DT.120769466 DT.120769488 DT.120769477 24/339 AceView cDNA sequences (see all 339): BQ574225 AL513736 AA135339 BX447379 AA906480 CB243717 AI291070 AA450275 AI056528 CD243371 BX367292 BQ004159 AA831369 W02879 BQ944893 CR626847 AI769683 BM663581 BQ009960 BQ956932 BU182223 BQ668939 BU844376 BU633373
GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for CDC16 (see all 14) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | - | | | | - | | - | | | | - | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | - | | | | - | | - | | | | - | | |
| SP3: | | | | | | | | | | | | | - | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | - | | | | - | | - | | | | - | | |
| SP4: | | | | | | | | | | | | | - | | | | | | | | - | | | | - | | | | | | | | | | | | - | | - | | - | | | | - | | - | | | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | - | | | | - | |
| ExUns: | 17b | · | 17c | · | 17d | ^ | 18a | · | 18b | ^ | 19a | · | 19b | · | 19c | · | 19d | ^ | 20 |
|---|
|
| SP1: | - | | | | | | - | | | | | | | | | | | | | | |
| SP2: | - | | | | | | - | | | | | | | | | | | | | | |
| SP3: | - | | | | | | - | | | | | | | | | | | | | | |
| SP4: | - | | | | | | - | | | | | | | | | | | | | | |
| SP5: | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CDC16
|
Expression
for CDC16 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CDC16 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGTTAGAGA
About this image
See CDC16 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CDC16
SOURCE GeneReport for Unigene cluster: Hs.374127
SABiosciences Expression via Pathway-Focused PCR Arrays including CDC16:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDC16
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CDC16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDC16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDC16 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDC16 |
Orthologs
for CDC16 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CDC16 gene from 10/31 species (see all 31) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Cdc161 , 5 |
CDC16 cell division cycle 16 homolog (S. cerevisiae)5
CDC16 cell division cycle 161 |
88.23(n)1
95.48(a)1 |
|
8 (6.38 cM)5
699571 NM_027276.21 NP_081552.21
137576765 |
chicken
(Gallus gallus) |
Aves |
CDC161 |
cell division cycle 16 homolog (S. cerevisiae) |
82.82(n)
92.57(a) |
|
418735 NM_001006265.1 NP_001006265.1 |
lizard
(Anolis carolinensis) |
Reptilia |
CDC166 |
-- |
85(a) |
1 ↔ 1 |
3(106757007-106774299) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.238062 |
Xenopus laevis transcribed sequence with moderate similarity more |
83.7(n) |
|
BQ735960.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
cdc161 |
cell division cycle 16 homolog (S. cerevisiae) |
72.29(n)
81.34(a) |
|
562014 NM_001037389.1 NP_001032466.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
cdc161 , 3 |
mitotic anaphase ubiquitin-protein ligase3
CG6759-PA1 |
50(a)3
52.17(n)1
47.65(a)1 |
|
94E93
427531 NM_058049.41 NP_477397.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
emb-273 |
-- |
24(a) |
|
II(8159851-8162091) -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
CDC16(YKL022C)4
CDC161 |
Subunit of the anaphase-promoting complex/cyclosome more4
Cdc16p1 |
46.27(n)1
33.4(a)1 |
|
11(397248-394726)4
8538461, 4 NP_012903.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
APC61 |
anaphase-promoting complex subunit 6 |
51.82(n)
44.55(a) |
|
844213 NM_106524.2 NP_565188.1 |
rice
(Oryza sativa) |
Liliopsida |
-- |
tetratricopeptide repeat domain containing protein... |
29(a) |
1 ↔ 1 |
3(7210427-7220255) |
ENSEMBL Gene Tree for CDC16 (if available)
TreeFam Gene Tree for CDC16 (if available) |
Paralogs
for CDC16 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CDC16 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CDC16 (115000362 - 115038198 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CDC16
1 CNV: 71827 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDC16 |
|
Disorders
/ Diseases
for CDC16 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CDC16 for disorders About GeneDecksing
OMIM gene information: 603461
OMIM disorders: --
10  diseases for CDC16: About MalaCardscolon carcinoma hepatocellular carcinoma colon cancer pancreatic cancer
colorectal cancer breast cancer pancreatitis carcinoma
neuronitis retinoblastoma
Human Genome Epidemiology (HuGE) Navigator: CDC16 (2 documents)
Export disorders for CDC16 gene to outside databases
|
Publications
for CDC16 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CDC16 gene, integrated from 9 sources (see all 71):
(articles sorted by number of sources associating them with CDC16) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition. (PubMed id 7736578)1, 2, 3, 9 Tugendreich S.... Hieter P. (1995)
- The serine/threonine phosphatase PP5 interacts with CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase- promoting complex. (PubMed id 9405394)1, 2, 9 Ollendorff V. and Donoghue D.J. (1997)
- Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. (PubMed id 18485873)1, 2 Jin L....Rape M. (2008)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. (PubMed id 16364912)1, 2 Dube P.... Stark H. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Mitotic regulation of the human anaphase-promoting complex by phosphorylation. (PubMed id 14657031)1, 2 Kraft C....Peters J.-M. (2003)
- Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events. (PubMed id 9628895)1, 2 Kallio M.... Gorbsky G.J. (1998)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
|
External Searches for CDC16 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CDC16 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing CDC16 gene
(According to HUGE)
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Specialized Databases showing CDC16 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for CDC16 gene:
Search GeneIP for patents involving CDC16
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CDC16 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CDC16 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CDC16 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDC16 | | | OriGene Protein Over-expression Lysate for CDC16 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CDC16 | | OriGene 3'-UTR Clone for CDC16 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDC16 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDC16 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CDC16 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CDC16 | | OriGene Custom Protein Services for CDC16 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CDC16 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDC16 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDC16 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDC16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDC16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDC16 |
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| | Antibodies & Assays for CDC16 |
| | | | Search Tocris compounds for CDC16 |
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 | | | CDC16 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDC16 |
|  |  |  | | | | ThermoFisher Antibodies for CDC16 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDC16 |
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