CYSLTR2 Gene
protein-coding GIFtS: 60
GCID: GC13P049280
|
|
cysteinyl leukotriene receptor 2
| |
Aliases
for CYSLTR2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cysteinyl Leukotriene Receptor 21 2 | | CysLT(2)1 | | CYSLT2R1 2 3 | | HG572 | | CYSLT22 3 5 | | KPG_0112 | | HPN3212 3 | | Cysteinyl Leukotriene CysLT2 Receptor2 | | G-Protein Coupled Receptor GPCR212 3 | | G Protein-Coupled Receptor2 | | G-Protein Coupled Receptor HG572 3 | | CysLTR23 | | HGPCR211 | | |
Export aliases for CYSLTR2 gene to outside databasesPrevious GC identifers: GC13P047280 GC13P043268 GC13P048217 GC13P047078 GC13P048178 GC13P030074 |
Summaries
for CYSLTR2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CYSLTR2:
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologicstudies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this geneand CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play amajor role in endocrine and cardiovascular systems. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CLTR2_HUMAN, Q9NS75Function: Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates aphosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specificcontractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascularendothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4
 summary
for CYSLTR2: Leukotriene and related receptors are activated by the endogenous ligands leukotriene (LT) B4, LTC4, LTD4,
LTE4 and 12-HETE. Leukotrienes are lipid mediators synthesized from arachidonic acid by lipoxygenase
enzymes. They act on peroxisome-proliferating receptors (PPARs) as well as the G-protein-coupled leukotriene
receptors, and are important in inflammatory signaling pathways. Leukotriene and related receptors are high
affinity stereoselective receptors that have a wide biological distribution. CysLT1 and CysLT2 receptors are
expressed most abundantly on myeloid cells. CysLT2 has a suppressive effect on CysLT1 expression, suggesting
that it has an autoregulatory role on CysLT1 levels. The main role of CysLT receptors is contraction of
vascular, respiratory and gastrointestinal smooth muscle.
Gene Wiki entry for CYSLTR2 (Cysteinyl leukotriene receptor 2)
|
Genomic Views
for CYSLTR2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024524.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CYSLTR2 gene promoter:
c-Fos POU2F1 AP-1 POU2F1a ATF-2 c-Jun POU3F2
Other transcription factors
Search SABiosciences Chromatin IP Primers for CYSLTR2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYSLTR2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q14.2 Ensembl cytogenetic band: 13q14.2 HGNC cytogenetic band: 13q14.2CYSLTR2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13P049280: view genomic region
(about GC identifiers)
Start:
|
49,280,951 bp from pter |
End:
|
49,283,498 bp from pter |
Size:
|
2,548 bases |
Orientation:
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plus strand |
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Proteins
for CYSLTR2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CLTR2_HUMAN, Q9NS75 (See
protein sequence)Recommended Name: Cysteinyl leukotriene receptor 2 Size: 346 amino acids; 39635 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: Q9HCQ2Explore the universe of human proteins at neXtProt for CYSLTR2: NX_Q9NS75
CYSLTR2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_065110.1
ENSEMBL proteins: ENSP00000282018 Reactome Protein details: Q9NS75
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
CYSLTR2 for ontologies About GeneDecksing
CYSLTR2 Antibody Products:
Assay Products for CYSLTR2: |
Protein
Domains /
Families
for CYSLTR2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CYSLTR2 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NS75ProtoNet protein and cluster: Q9NS75 1 Blocks protein family: IPB004071 Cysteinyl leukotriene receptor family signature
UniProtKB/Swiss-Prot: CLTR2_HUMAN, Q9NS75Similarity: Belongs to the G-protein coupled receptor 1 family |
Function
for CYSLTR2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CLTR2_HUMAN, Q9NS75Function: Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates aphosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specificcontractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascularendothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4
Clone
Products: |  | EMD Millipore Clones for the Expression of CYSLTR2 | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYSLTR2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYSLTR2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CYSLTR2 (NM_020377) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CYSLTR2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYSLTR2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYSLTR2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001631 | cysteinyl leukotriene receptor activity |
IEA | -- | | GO:0004974 | leukotriene receptor activity |
NAS | 10913337 |
CYSLTR2 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Cysltr2tm1Ykn for CYSLTR2
5 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Cysltr2):
CYSLTR2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CYSLTR2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Class A/1 (Rhodopsin-like receptors) | | | 2 | Signaling by GPCR | | | 3 | G alpha (q) signalling events | | | 4 | Prostanoid ligand receptors | | | 5 | Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for CYSLTR2
1  GeneGo (Thomson Reuters) Pathway for CYSLTR2
2  BioSystems Pathways for CYSLTR2
5/9 
Reactome Pathways for CYSLTR2 (see all 9)
2 
Kegg Pathways (Kegg details for CYSLTR2):
CYSLTR2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CYSLTR2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/126 Interacting proteins for CYSLTR2 (ENSP000002820184) via UniProtKB, MINT, STRING, and/or I2D (see all 126)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
CYSLTR2 for ontologies About GeneDecksing
|
Drugs & Compounds
for CYSLTR2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CYSLTR2 for compounds About GeneDecksing
Compounds for CYSLTR2 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| BAY-u 9773 | Dual CysLT1 and CysLT2 antagonist | [154978-38-8] | | FPL 55712 | Leukotriene receptor antagonist | [40786-08-1] |
1 HMDB Compound for CYSLTR2 About this table
1 DrugBank Compound for CYSLTR2 About this table
10/35 Novoseek chemical compound relationships for CYSLTR2 gene (see all 35) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ltd4 |
76.5 |
7 |
17941281 (2), 9647602 (1), 10913337 (1), 18174606 (1) |
| montelukast |
72.9 |
5 |
17208594 (1), 17460547 (1), 18503712 (1), 19563734 (1) |
| leukotriene b4 |
65.7 |
11 |
15544591 (2), 12787679 (1), 15869882 (1), 20097180 (1) (see all 5) |
| lte4 |
64.2 |
3 |
9647602 (1), 16304255 (1), 20201353 (1) |
| 5-oxoete |
58.8 |
1 |
16159627 (1) |
| gdp |
43 |
1 |
16190775 (1) |
| pgd2 |
42.9 |
2 |
17154652 (1) |
| aequorin |
39.9 |
1 |
18566482 (1) |
| calcium |
34.6 |
11 |
12816881 (2), 15643983 (1), 15140381 (1), 16620134 (1) (see all 10) |
| gtp |
32.8 |
3 |
16190775 (1), 10603489 (1), 12719528 (1) |
Search CenterWatch for drugs/clinical trials and news about CYSLTR2 / CLTR2
|
Transcripts
for CYSLTR2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CYSLTR2 gene: NM_020377.2 Unigene Clusters for CYSLTR2: Cysteinyl leukotriene receptor 2 Hs.253706 [show with all ESTs], Hs.614318 [show with all ESTs]Unigene Representative Sequences: AB038269, AK2917391 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000282018(uc001vck.2 uc021rjl.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYSLTR2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYSLTR2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CYSLTR2 (NM_020377) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CYSLTR2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYSLTR2 |
Additional cDNA sequence: AK291739.1 AY853711.1 BC096832.1 EF141523.1 EF141524.1 EF141525.1 EF141526.1 EF141527.1 EF141528.1 EF141529.1 EF141530.1 3 DOTS entries: DT.75178411 DT.120795348 DT.100670790 20 AceView cDNA sequences: CD630087 BX280531 CD630084 BC069160 CD630086 CD630072 CD630089 CD630081 CD630079 NM_020377 CD630069 CD630074 AW235714 CD630067 AB038269 CF147785 CD630075 CD630077 CD630066 BX481095
GeneLoc Exon Structure
|
Expression
for CYSLTR2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CYSLTR2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCATTGTAC
About this image
See CYSLTR2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CYSLTR2
SOURCE GeneReport for Unigene clusters: Hs.253706 Hs.614318
UniProtKB/Swiss-Prot: CLTR2_HUMAN, Q9NS75Tissue specificity: Widely expressed, with highest levels in the heart, placenta, spleen, peripheral blood leukocytesand adrenal gland. In lung, expressed in the interstitial macrophages, and slightly in smooth muscle cells
SABiosciences Expression via Pathway-Focused PCR Array including CYSLTR2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYSLTR2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CYSLTR2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYSLTR2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYSLTR2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYSLTR2 |
Orthologs
for CYSLTR2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CYSLTR2 gene from 2/8 species (see all 8) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CYSLTR21 |
cysteinyl leukotriene receptor 2 |
62.19(n)
55.41(a) |
|
428071 XM_425629.1 XP_425629.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1003349631 |
cysteinyl leukotriene receptor 1-like |
51.26(n)
44.86(a) |
|
100334963 XM_002662545.2 XP_002662591.2 |
ENSEMBL Gene Tree for CYSLTR2 (if available)
TreeFam Gene Tree for CYSLTR2 (if available) |
Paralogs
for CYSLTR2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CYSLTR2 gene
- OXGR12 P2RY42 GPR172 P2RY12 P2RY112 P2RY62 GPR1742 LPAR62
- LPAR52 CYSLTR12 GPR1832 LPAR42 P2RY102 SUCNR12 P2RY22 PTAFR2
18/52 SIMAP similar genes for CYSLTR2 using alignment to 2 protein entries: CLTR2_HUMAN (see all proteins)
(see all similar genes):KPG_011 CYSLTR1 OXGR1 P2RY1 GPR17 F2RL1
LPAR4 P2RY2 GPR34 GPR30 LPAR6 P2RY5
AGTR2 GPR183 SSTR4 CCR5 GPR68 CCR1
CYSLTR2 for paralogs About GeneDecksing
|
Genomic Variants
for CYSLTR2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CYSLTR2 (49280951 - 49283498 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CYSLTR2
1 CNV: 0168
Human Gene Mutation Database (HGMD): CYSLTR2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYSLTR2 |
|
Disorders
/ Diseases
for CYSLTR2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CYSLTR2 for disorders About GeneDecksing
OMIM gene information: 605666
OMIM disorders: --
20/32  diseases for CYSLTR2 (see all 32): About MalaCardsasthma bronchial asthma traumatic brain injury brain injury
kaposi's sarcoma allergic rhinitis atopic dermatitis atopy
insulin resistance rhinitis cystic fibrosis fainting
dermatitis sarcoma rabies ischemia
sinusitis atherosclerosis leiomyoma obesity
2 diseases from the University of Copenhagen DISEASES database for CYSLTR2:Asthma Allergic rhinitis 10/19 Novoseek disease relationships for CYSLTR2 gene (see all 19) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| asthma |
50.6 |
36 |
16304255 (5), 15475736 (4), 15454733 (3), 15970796 (2) (see all 13) |
| asthma allergic |
36.2 |
3 |
15454733 (1), 17558309 (1) |
| inflammation |
31.1 |
11 |
17693579 (2), 18048362 (1), 18395849 (1), 20064706 (1) (see all 9) |
| kaposi sarcoma |
30.1 |
4 |
10987301 (1), 19258523 (1), 12816350 (1), 15688008 (1) |
| atherosclerosis |
21.2 |
2 |
12193079 (1), 12816350 (1) |
| atopy |
19.4 |
1 |
14515063 (1) |
| cardiovascular diseases |
13.8 |
1 |
10790351 (1) |
| nasal polyps |
10.7 |
2 |
16689996 (1) |
| myocardial infarction |
0 |
1 |
12816881 (1) |
| heart diseases |
0 |
2 |
17557938 (2) |
Genetic Association Database (GAD): CYSLTR2
Human Genome Epidemiology (HuGE) Navigator: CYSLTR2 (14 documents)
Export disorders for CYSLTR2 gene to outside databases
|
Publications
for CYSLTR2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CYSLTR2 gene, integrated from 9 sources (see all 215):
(articles sorted by number of sources associating them with CYSLTR2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT2 receptor. (PubMed id 10913337)1, 2, 3, 9 Takasaki J....Furuichi K. (2000)
- Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics. (PubMed id 15970796)1, 4, 9 Park J.S....Shin H.D. (2005)
- Characterization of the human cysteinyl leukotriene 2 receptor. (PubMed id 10851239)1, 2, 9 Heise C.E.... Evans J.F. (2000)
- A cysteinyl leukotriene 2 receptor variant is associated with atopy in the population of Tristan da Cunha. (PubMed id 14515063)1, 4, 9 Thompson M.D....O'Dowd B.F. (2003)
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Identification of G protein-coupled receptor genes from the human genome sequence. (PubMed id 12044878)1, 2 Takeda S.... Mitaku S. (2002)
- Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. (PubMed id 11093801)1, 2 Nothacker H.-P....Civelli O. (2000)
- L-Sorbose metabolism in Agrobacterium tumefaciens. (PubMed id 1085123)1, 3 Van Keer C....De Ley J. (1976)
- Levels of cysteinyl leukotriene receptor mRNA in human peripheral leucocytes: significantly higher expression of cysteinyl leukotriene receptor 2 mRNA in eosinophils. (PubMed id 11696047)1, 9 Mita H....Akiyama K. (2001)
|
External Searches for CYSLTR2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CYSLTR2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CYSLTR2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CYSLTR2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for CYSLTR2 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for CYSLTR2 gene:
Search GeneIP for patents involving CYSLTR2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CYSLTR2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for CYSLTR2 | | OriGene shRNA RFP for CYSLTR2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CYSLTR2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYSLTR2 | | | OriGene Protein Over-expression Lysate for CYSLTR2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CYSLTR2 | | OriGene 3'-UTR Clone for CYSLTR2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYSLTR2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYSLTR2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CYSLTR2 | | OriGene Custom Protein Services for CYSLTR2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CYSLTR2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYSLTR2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYSLTR2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CYSLTR2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYSLTR2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYSLTR2 |
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 | | | CYSLTR2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYSLTR2 |
|  |  |  | | | | Search ThermoFisher Antibodies for CYSLTR2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYSLTR2 |
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