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Aliases for CYP4Z2P Gene

Aliases for CYP4Z2P Gene

  • Cytochrome P450 Family 4 Subfamily Z Member 2, Pseudogene 2 3 5
  • Cytochrome P450, Family 4, Subfamily Z, Polypeptide 2, Pseudogene 2

External Ids for CYP4Z2P Gene

Previous GeneCards Identifiers for CYP4Z2P Gene

  • GC01M046695
  • GC01M046678
  • GC01M046693
  • GC01M047035
  • GC01M047309
  • GC01M045439

Summaries for CYP4Z2P Gene

GeneCards Summary for CYP4Z2P Gene

CYP4Z2P (Cytochrome P450 Family 4 Subfamily Z Member 2, Pseudogene) is a Pseudogene. GO annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP4Z2P Gene

Genomics for CYP4Z2P Gene

Regulatory Elements for CYP4Z2P Gene

Enhancers for CYP4Z2P Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CYP4Z2P on UCSC Golden Path with GeneCards custom track

Genomic Location for CYP4Z2P Gene

46,843,095 bp from pter
46,900,475 bp from pter
57,381 bases
Minus strand

Genomic View for CYP4Z2P Gene

Genes around CYP4Z2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CYP4Z2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CYP4Z2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CYP4Z2P Gene

Proteins for CYP4Z2P Gene

  • Protein details for CYP4Z2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative inactive cytochrome P450 family member 4Z2
    Protein Accession:
    Secondary Accessions:
    • Q66ZJ5

    Protein attributes for CYP4Z2P Gene

    340 amino acids
    Molecular mass:
    40159 Da
    Name=heme; Xref=ChEBI:CHEBI:30413;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CYP4Z2P Gene


neXtProt entry for CYP4Z2P Gene

Proteomics data for CYP4Z2P Gene at MOPED

Post-translational modifications for CYP4Z2P Gene

No Post-translational modifications

No data available for DME Specific Peptides for CYP4Z2P Gene

Domains & Families for CYP4Z2P Gene

Gene Families for CYP4Z2P Gene

Protein Domains for CYP4Z2P Gene


Suggested Antigen Peptide Sequences for CYP4Z2P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the cytochrome P450 family.
  • Belongs to the cytochrome P450 family.
genes like me logo Genes that share domains with CYP4Z2P: view

Function for CYP4Z2P Gene

Gene Ontology (GO) - Molecular Function for CYP4Z2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0020037 heme binding IEA --
genes like me logo Genes that share ontologies with CYP4Z2P: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CYP4Z2P Gene

Localization for CYP4Z2P Gene

Subcellular locations from UniProtKB/Swiss-Prot for CYP4Z2P Gene

Membrane; Single-pass type II membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CYP4Z2P Gene

Pathways & Interactions for CYP4Z2P Gene

SuperPathways for CYP4Z2P Gene

No Data Available

Interacting Proteins for CYP4Z2P Gene

Selected Interacting proteins: Q8N1L4-CP4Z2_HUMAN for CYP4Z2P Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for CYP4Z2P Gene


No data available for Pathways by source and SIGNOR curated interactions for CYP4Z2P Gene

Drugs & Compounds for CYP4Z2P Gene

No Compound Related Data Available

Transcripts for CYP4Z2P Gene

mRNA/cDNA for CYP4Z2P Gene

(2) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CYP4Z2P Gene

Cytochrome P450, family 4, subfamily Z, polypeptide 2 pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CYP4Z2P Gene

No ASD Table

Relevant External Links for CYP4Z2P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CYP4Z2P Gene

mRNA expression in normal human tissues for CYP4Z2P Gene

mRNA differential expression in normal tissues according to GTEx for CYP4Z2P Gene

This gene is overexpressed in Breast - Mammary Tissue (x16.1).

SOURCE GeneReport for Unigene cluster for CYP4Z2P Gene Hs.591431

mRNA Expression by UniProt/SwissProt for CYP4Z2P Gene

Tissue specificity: Detected at low levels in mammary gland and mammary carcinoma.
genes like me logo Genes that share expression patterns with CYP4Z2P: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for CYP4Z2P Gene

Orthologs for CYP4Z2P Gene

Evolution for CYP4Z2P Gene

Gene Tree for CYP4Z2P (if available)
Gene Tree for CYP4Z2P (if available)

No data available for Orthologs for CYP4Z2P Gene

Paralogs for CYP4Z2P Gene

(13) SIMAP similar genes for CYP4Z2P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CYP4Z2P: view

No data available for Paralogs for CYP4Z2P Gene

Variants for CYP4Z2P Gene

Sequence variations from dbSNP and Humsavar for CYP4Z2P Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1002377 -- 46,888,616(-) agtgg(C/T)ctttc intron-variant
rs1338091 -- 46,883,755(-) GAGAA(C/T)AAGAA intron-variant
rs1338092 -- 46,883,734(-) TTCCT(C/T)TCTAA intron-variant
rs1553387 -- 46,889,162(-) ttaat(C/T)agggc intron-variant
rs1553388 -- 46,889,161(-) taatc(A/G)gggca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CYP4Z2P Gene

Variant ID Type Subtype PubMed ID
nsv525401 CNV Loss 19592680
esv2747930 CNV Deletion 23290073
esv2670875 CNV Deletion 23128226
dgv220n71 CNV Gain 21882294

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for CYP4Z2P Gene

Disorders for CYP4Z2P Gene

Relevant External Links for CYP4Z2P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CYP4Z2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CYP4Z2P Gene

Publications for CYP4Z2P Gene

  1. Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma. (PMID: 15059886) Rieger M.A. … Weigle B. (Cancer Res. 2004) 2 3 4 67
  2. The 3'UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1. (PMID: 25701119) Zheng L. … Xi T. (Breast Cancer Res. Treat. 2015) 3
  3. An atlas of genetic influences on human blood metabolites. (PMID: 24816252) Shin S.Y. … Soranzo N. (Nat. Genet. 2014) 3
  4. Pseudogene CYP4Z2P 3'UTR promotes angiogenesis in breast cancer. (PMID: 25281903) Zheng L. … Xi T. (Biochem. Biophys. Res. Commun. 2014) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for CYP4Z2P Gene

Sources for CYP4Z2P Gene