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Aliases for CYP4Z2P Gene

Aliases for CYP4Z2P Gene

  • Cytochrome P450, Family 4, Subfamily Z, Polypeptide 2, Pseudogene 2 3

External Ids for CYP4Z2P Gene

Summaries for CYP4Z2P Gene

GeneCards Summary for CYP4Z2P Gene

CYP4Z2P (Cytochrome P450, Family 4, Subfamily Z, Polypeptide 2, Pseudogene) is a Pseudogene. GO annotations related to this gene include electron carrier activity and heme binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP4Z2P Gene

Genomics for CYP4Z2P Gene

Genomic Location for CYP4Z2P Gene

Start:
46,843,095 bp from pter
End:
46,900,475 bp from pter
Size:
57,381 bases
Orientation:
Minus strand

Genomic View for CYP4Z2P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CYP4Z2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CYP4Z2P Gene

Regulatory Elements for CYP4Z2P Gene

Proteins for CYP4Z2P Gene

  • Protein details for CYP4Z2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N1L4-CP4Z2_HUMAN
    Recommended name:
    Putative inactive cytochrome P450 family member 4Z2
    Protein Accession:
    Q8N1L4
    Secondary Accessions:
    • Q66ZJ5

    Protein attributes for CYP4Z2P Gene

    Size:
    340 amino acids
    Molecular mass:
    40159 Da
    Cofactor:
    Name=heme; Xref=ChEBI:CHEBI:30413;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CYP4Z2P Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CYP4Z2P Gene

Proteomics data for CYP4Z2P Gene at MOPED

Post-translational modifications for CYP4Z2P Gene

No Post-translational modifications

No data available for DME Specific Peptides for CYP4Z2P Gene

Domains for CYP4Z2P Gene

Gene Families for CYP4Z2P Gene

HGNC:
  • CYP :Cytochrome P450s

Protein Domains for CYP4Z2P Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

CP4Z2_HUMAN
Family:
  • Belongs to the cytochrome P450 family.:
    • Q8N1L4
genes like me logo Genes that share domains with CYP4Z2P: view

Function for CYP4Z2P Gene

Gene Ontology (GO) - Molecular Function for CYP4Z2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005506 iron ion binding IEA --
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA --
GO:0020037 heme binding IEA --
genes like me logo Genes that share ontologies with CYP4Z2P: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CYP4Z2P Gene

Localization for CYP4Z2P Gene

Subcellular locations from UniProtKB/Swiss-Prot for CYP4Z2P Gene

Membrane; Single-pass type II membrane protein.

Gene Ontology (GO) - Cellular Components for CYP4Z2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CYP4Z2P: view

Pathways for CYP4Z2P Gene

SuperPathways for CYP4Z2P Gene

No Data Available

Interacting Proteins for CYP4Z2P Gene

Selected Interacting proteins: Q8N1L4-CP4Z2_HUMAN for CYP4Z2P Gene via I2D

Symbol External ID(s) Details
GABARAPL1

Gene Ontology (GO) - Biological Process for CYP4Z2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with CYP4Z2P: view

No data available for Pathways by source for CYP4Z2P Gene

Compounds for CYP4Z2P Gene

(1) HMDB Compounds for CYP4Z2P Gene

Compound Synonyms Cas Number PubMed IDs
Heme
  • (protoporphyrinato)iron
14875-96-8
genes like me logo Genes that share compounds with CYP4Z2P: view

Transcripts for CYP4Z2P Gene

mRNA/cDNA for CYP4Z2P Gene

(2) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CYP4Z2P Gene

Cytochrome P450, family 4, subfamily Z, polypeptide 2 pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CYP4Z2P Gene

No ASD Table

Relevant External Links for CYP4Z2P Gene

GeneLoc Exon Structure for
CYP4Z2P
ECgene alternative splicing isoforms for
CYP4Z2P

Expression for CYP4Z2P Gene

mRNA expression in normal human tissues for CYP4Z2P Gene

mRNA differential expression in normal tissues according to GTEx for CYP4Z2P Gene

This gene is overexpressed in Breast - Mammary Tissue (16.1).

SOURCE GeneReport for Unigene cluster for CYP4Z2P Gene Hs.591431

mRNA Expression by UniProt/SwissProt for CYP4Z2P Gene

Q8N1L4-CP4Z2_HUMAN
Tissue specificity: Detected at low levels in mammary gland and mammary carcinoma.
genes like me logo Genes that share expressions with CYP4Z2P: view

Orthologs for CYP4Z2P Gene

Evolution for CYP4Z2P Gene

ENSEMBL:
Gene Tree for CYP4Z2P (if available)
TreeFam:
Gene Tree for CYP4Z2P (if available)

No data available for Orthologs for CYP4Z2P Gene

Paralogs for CYP4Z2P Gene

Selected SIMAP similar genes for CYP4Z2P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CYP4Z2P: view

No data available for Paralogs for CYP4Z2P Gene

Variants for CYP4Z2P Gene

Sequence variations from dbSNP and Humsavar for CYP4Z2P Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1002377 -- 46,888,616(-) agtgg(C/T)ctttc intron-variant
rs1338091 -- 46,883,755(-) GAGAA(C/T)AAGAA intron-variant
rs1393661 -- 46,888,816(-) cccct(C/G)tcctt intron-variant
rs1393662 -- 46,888,731(-) aggaa(A/T)cagaa intron-variant
rs1393663 -- 46,888,661(-) ggcaa(A/G)gctaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CYP4Z2P Gene

Variant ID Type Subtype PubMed ID
nsv525401 CNV Loss 19592680
esv2747930 CNV Deletion 23290073
esv2670875 CNV Deletion 23128226
dgv220n71 CNV Gain 21882294

Relevant External Links for CYP4Z2P Gene

HapMap Linkage Disequilibrium report
CYP4Z2P

Disorders for CYP4Z2P Gene

No disorders were found for CYP4Z2P Gene.

No data available for UniProtKB/Swiss-Prot for CYP4Z2P Gene

Publications for CYP4Z2P Gene

  1. Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma. (PMID: 15059886) Rieger M.A. … Weigle B. (Cancer Res. 2004) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. (PMID: 15128046) Nelson D.R. … Nebert D.W. (Pharmacogenetics 2004) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. An atlas of genetic influences on human blood metabolites. (PMID: 24816252) Shin S.Y. … Soranzo N. (Nat. Genet. 2014) 3

Products for CYP4Z2P Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate CYP4Z2P
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for CYP4Z2P
    • Block miRNA regulation of CYP4Z2P using miScript Target Protectors

    Sources for CYP4Z2P Gene

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