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CYP4Z1 Gene

protein-coding   GIFtS: 48
GCID: GC01P047533

Cytochrome P450, Family 4, Subfamily Z, Polypeptide 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cytochrome P450, Family 4, Subfamily Z, Polypeptide 11 2
CYPIVZ12 3
CYP4A202
Cytochrome P450 4Z12
EC 1.14.14.13

External Ids:    HGNC: 205831   Entrez Gene: 1999742   Ensembl: ENSG000001861607   UniProtKB: Q86W103   

Export aliases for CYP4Z1 gene to outside databases

Previous GC identifers: GC01P046923 GC01P046903 GC01P046902 GC01P047245 GC01P047305 GC01P045649


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CYP4Z1 Gene:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids
and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. (provided by
RefSeq, Jul 2008)

GeneCards Summary for CYP4Z1 Gene:
CYP4Z1 (cytochrome P450, family 4, subfamily Z, polypeptide 1) is a protein-coding gene. Diseases associated with CYP4Z1 include tuberculosis, and lung cancer. GO annotations related to this gene include electron carrier activity and heme binding. An important paralog of this gene is CYP4F22.

Gene Wiki entry for CYP4Z1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the CYP4Z1 gene promoter:
         LHX3b/Lhx3b   AML1a   Pax-5   Nkx2-2   Gfi-1   RORalpha1   PPAR-alpha   LHX3a/Lhx3a   ARP-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCYP4Z1 promoter sequence
   Search Chromatin IP Primers for CYP4Z1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CYP4Z1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p33   Ensembl cytogenetic band:  1p33   HGNC cytogenetic band: 1p33

CYP4Z1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CYP4Z1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P047533:  view genomic region     (about GC identifiers)

Start:
47,533,160 bp from pter      End:
47,583,992 bp from pter
Size:
50,833 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CP4Z1_HUMAN, Q86W10 (See protein sequence)
Recommended Name: Cytochrome P450 4Z1  
Size: 505 amino acids; 59086 Da
Cofactor: Heme group (By similarity)
Secondary accessions: Q5VVE4

Explore the universe of human proteins at neXtProt for CYP4Z1: NX_Q86W10

Explore proteomics data for CYP4Z1 at MOPED


See CYP4Z1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_835235.1  
ENSEMBL proteins: 
 ENSP00000334246  

CYP4Z1 Human Recombinant Protein Products:

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CYP4Z1 Assay Products:

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Cloud-Clone Corp. ELISAs for CYP4Z1
Cloud-Clone Corp. CLIAs for CYP4Z1


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
CYP: Cytochrome P450s

IUPHAR Guide to PHARMACOLOGY protein family classification: CYP4Z1
CYP4 family

3 InterPro protein domains:
 IPR001128 Cyt_P450
 IPR017972 Cyt_P450_CS
 IPR002401 Cyt_P450_E_grp-I

Graphical View of Domain Structure for InterPro Entry Q86W10

ProtoNet protein and cluster: Q86W10

UniProtKB/Swiss-Prot: CP4Z1_HUMAN, Q86W10
Similarity: Belongs to the cytochrome P450 family


CYP4Z1 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CP4Z1_HUMAN, Q86W10
Catalytic activity: RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O

     Enzyme Number (IUBMB): EC 1.14.14.11

     Gene Ontology (GO): 4 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005506iron ion binding IEA--
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ----
GO:0020037heme binding IEA--
GO:0070330aromatase activity IEA--
     
CYP4Z1 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CYP4Z1
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miRNA
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Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat CYP4Z1

Gene Editing
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP4Z1

Cell Line
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In Situ Assay
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CP4Z1_HUMAN, Q86W10: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane;
Single-pass type II membrane protein
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
endoplasmic reticulum5
extracellular2
golgi apparatus1
peroxisome1
plasma membrane1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005789endoplasmic reticulum membrane IEA--
GO:0016021integral component of membrane IEA--

CYP4Z1 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for CYP4Z1 About    
See pathways by source

SuperPathContained pathways About
1Cytochrome P450 - arranged by substrate type
cytochrome P4500.74
2Biological oxidations
metapathway biotransformation0.42


2 BioSystems Pathways for CYP4Z1
    cytochrome P450
metapathway biotransformation


    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CYP4Z1
Interactions:

    Search GeneGlobe Interaction Network for CYP4Z1

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

Selected Interacting proteins for CYP4Z1 (ENSP000003342464) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
InteractantInteraction Details
GeneCardExternal ID(s)
LSSENSP000003487624STRING: ENSP00000348762
SIGMAR1ENSP000002770104STRING: ENSP00000277010
SQLEENSP000002658964STRING: ENSP00000265896
AGMOENSP000003416624STRING: ENSP00000341662
HSD17B7ENSP000002545214STRING: ENSP00000254521
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Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0055114oxidation-reduction process ----

CYP4Z1 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CYP4Z1 (CP4Z1)

Selected HMDB Compounds for CYP4Z1 (see all 49)    About this table
CompoundSynonyms CAS #PubMed Ids
10-HETE10-hydroxyeicosa-all-cis-5,8,11,14-tetraenoate (see all 2)167697-52-1--
11,12,15-THETA11,12,15-Trihydroxyicosatrienoic acid (see all 5)----
11,12-Epoxyeicosatrienoic acid10-(3-(2-octenyl)oxiranyl)-5,8-Decadienoic acid (see all 15)81276-02-0--
11,14,15-THETA(5Z,8Z,12E)-11,14,15-Trihydroxyeicosa-5,8,12-trienoic acid (see all 8)----
11H-14,15-EETA14,15-Ep-11-HETrE (see all 11)219535-29-2--
11beta-Hydroxytestosterone11beta,17beta-dihydroxyandrost-4-en-3-one 1816-85-9--
12,13-EpOMEVernolic acid (see all 12)----
13-HETE13-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoate (see all 2)151910-72-4--
14,15-Epoxy-5,8,11-eicosatrienoic acid(5Z,8Z,11Z)-14,15-Epoxyicosa-5.8.11-trienoic acid (see all 11)81276-03-1--
15(S)-HPETE(5Z,8Z,11Z,13E)-(15S)-15-Hydroperoxyicosa-5,8,11,13-tetraenoate (see all 8)70981-96-3--



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for CYP4Z1 gene: 
NM_178134.2  

Unigene Cluster for CYP4Z1:

Cytochrome P450, family 4, subfamily Z, polypeptide 1
Hs.176588  [show with all ESTs]
Unigene Representative Sequence: AY358631
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000334194(uc001cqu.1) ENST00000471598
miRNA
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for CYP4Z1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP4Z1
Primer
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OriGene qPCR primer pairs and template standards for CYP4Z1
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Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CYP4Z1
  QuantiTect SYBR Green Assays in human, mouse, rat CYP4Z1
  QuantiFast Probe-based Assays in human, mouse, rat CYP4Z1

Additional mRNA sequence: 

AK292175.1 AY262056.1 AY358631.1 

2 DOTS entries:

DT.100742965  DT.106617 

22 AceView cDNA sequences:

NM_178134 AY358631 BG193485 H21976 AI733538 AI668594 AV700083 AY262056 
BG201072 BG210988 BX094680 BG218514 BG212152 AV689946 H25577 BG219391 
AI668602 AW472756 H25624 AI820775 BG204180 BG192933 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CYP4Z1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ATAGCTTTAT
CYP4Z1 Expression
About this image


CYP4Z1 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 3) fully expand
 
 Adipose (Muscoskeletal System)
         Mesenchymal Stem Cells Subcutaneous White Adipose
 
 Mesenchymal Stem Cells
         Mesenchymal Stem Cells Subcutaneous White Adipose
 
 Breast (Uncategorized)
CYP4Z1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CYP4Z1 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.176588

UniProtKB/Swiss-Prot: CP4Z1_HUMAN, Q86W10
Tissue specificity: Preferentially detected in breast carcinoma tissue and mammary gland, whereas only marginal
expression is found in all other tested tissues

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QuantiFast Probe-based Assays in human, mouse, rat CYP4Z1
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP4Z1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for CYP4Z1 gene from Selected species (see all 6)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
lizard
(Anolis carolinensis)
Reptilia --
--
(see all 4)
Uncharacterized protein
(see all 4)
49(a)
47(a)
(see all 4)
many ↔ many
many ↔ many
(see all 4)
GL343249.1(1880734-1908444)
GL343249.1(1942574-1982744)
African clawed frog
(Xenopus laevis)
Amphibia AB022671.12   -- 73.56(n)    AB022671.1 
        Species with no ortholog for CYP4Z1

ENSEMBL Gene Tree for CYP4Z1 (if available)
TreeFam Gene Tree for CYP4Z1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for CYP4Z1 gene
CYP4F222  TBXAS12  CYP4F32  CYP4F22  CYP4F112  CYP3A432  CYP3A42  CYP4A222  
CYP3A72  CYP4V22  CYP4B12  CYP3A52  CYP4A112  CYP4F122  CYP4X12  
14 SIMAP similar genes for CYP4Z1 using alignment to 1 protein entry:     CP4Z1_HUMAN:
CYP4Z2P    CYP4X1    CYP4A11    CYP4B1    CYP4F12    CYP4F2
CYP4F22    CYP4F8    CYP4F11    DKFZp761K058    CYP4F3    CYP4A22
CYP3A43/CYP3A4    CYP4V2

CYP4Z1 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for CYP4Z1
PGOHUM00000244006


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CYP4Z1 (see all 1092)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs2012299391,2
--45653614(+) TGGAT-/GATA  
        
GATAG
1 -- int10--------
rs22658941,2
C--45669990(-) ACTACC/TATCAG 1 -- int11Minor allele frequency- T:0.50NA 2
rs604997421,2
C--45693844(+) ATAAC-/AAAC  
        
CTACT
1 -- int11Minor allele frequency- AAAC:0.00NA 2
rs1117995881,2
C,F--47531230(+) TAGCAC/TCAAAT 1 -- us2k11Minor allele frequency- T:0.50WA 2
rs127574891,2
H--47531446(+) gatgaA/Gccatt 1 -- us2k14Minor allele frequency- G:0.00NS EA 412
rs127575011,2
H--47531462(+) gattaA/Tcgaag 1 -- us2k14Minor allele frequency- T:0.00NS EA 420
rs710500821,2
C--47542517(-) CATTC-/TTTTTT 1 -- int11Minor allele frequency- T:0.00NA 2
rs133740821,2
C,F,H--47550180(+) TTCATT/GTTGTA 1 -- int16Minor allele frequency- G:0.06NS EA NA WA 540
rs43472511,2
C,F,A--47551511(+) cccacC/Acccct 1 -- int1 trp32Minor allele frequency- A:0.25NA 4
rs597551991,2
C,F--47556189(+) TCTACG/AAATAA 1 -- int12Minor allele frequency- A:0.10WA 120

HapMap Linkage Disequilibrium report for CYP4Z1 (47533160 - 47583992 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for CYP4Z1:    About this table    
Variant IDTypeSubtypePubMed ID
esv24824CNV Loss19812545
dgv221n71CNV Gain21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CYP4Z1
DNA2.0 Custom Variant and Variant Library Synthesis for CYP4Z1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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3 diseases for CYP4Z1:    
About MalaCards
tuberculosis    lung cancer    breast cancer


CYP4Z1 for disorders           About GeneDecksing


Export disorders for CYP4Z1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CYP4Z1 gene, integrated from 10 sources (see all 11):
(articles sorted by number of sources associating them with CYP4Z1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma. (PubMed id 15059886)1, 2, 3, 9 Rieger M.A.... Weigle B. (Cancer Res. 2004)
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
  3. Conditional regulation of the human CYP4X1 and CYP4Z1 genes. (PubMed id 15797250)1, 9 Savas U....Johnson E.F. (Arch. Biochem. Biophys. 2005)
  4. Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer. (PubMed id 22841774)1 Yu W....Yang J. (Toxicol. Appl. Pharmacol. 2012)
  5. Identification of genes associated with non-small-cell lung cancer promotion and progression. (PubMed id 19473719)1 Bankovic J....Tanic N. (Lung Cancer 2010)
  6. Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid. (PubMed id 19090726)1 ZAPllner A....Bureik M. (Biol. Chem. 2009)
  7. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
  8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
  9. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. (PubMed id 15128046)1 Nelson D.R....Nebert D.W. (Pharmacogenetics 2004)
  10. The cytochrome P450 4 (CYP4) family. (PubMed id 9068972)1 Simpson A.E. (Gen. Pharmacol. 1997)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
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  Query String
PubMed
OMIM
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  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 199974 HGNC: 20583 AceView: CYP4Z1 Ensembl:ENSG00000186160 euGenes: HUgn199974
ECgene: CYP4Z1 H-InvDB: CYP4Z1

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CYP4Z1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CYP4Z1 gene:
Search GeneIP for patents involving CYP4Z1

GeneCards and IP:
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