Aliases for CYP3A7 Gene
Aliases for CYP3A7 Gene
External Ids for CYP3A7 Gene
- HGNC: 2640
- Entrez Gene: 1551
- Ensembl: ENSG00000160870
- OMIM: 605340
- UniProtKB: P24462
Previous GeneCards Identifiers for CYP3A7 Gene
- GC07M097828
- GC07M098890
- GC07M098904
- GC07M098938
- GC07M099135
- GC07M099123
- GC07M099293
- GC07M093939
- GC07M099702
Summaries for CYP3A7 Gene
-
This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015]
GeneCards Summary for CYP3A7 Gene
CYP3A7 (Cytochrome P450 Family 3 Subfamily A Member 7) is a Protein Coding gene. Among its related pathways are Metabolism and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. An important paralog of this gene is CYP3A7-CYP3A51P.
UniProtKB/Swiss-Prot for CYP3A7 Gene
-
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Additional gene information for CYP3A7 Gene
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP3A7 Gene
Genomics for CYP3A7 Gene
GeneHancer (GH) Regulatory Elements for CYP3A7 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH07I099735 | Promoter/Enhancer | 0.7 | EPDnew dbSUPER | 550.8 | +0.0 | 29 | 0.1 | CYP3A7 CYP3A7-CYP3A51P PIR41599 ZSCAN25 | ||
GH07I099737 | Enhancer | 0.7 | ENCODE dbSUPER | 0.8 | -2.7 | -2735 | 1.1 | ZNF680 ZNF600 PRDM1 ZNF518A | CYP3A5 CYP3A7 CYP3A7-CYP3A51P CYP3AP2 ZSCAN25 | |
GH07I099750 | Enhancer | 1.2 | Ensembl ENCODE dbSUPER | 0.4 | -16.9 | -16899 | 2.3 | DRAP1 MEIS2 PKNOX1 KLF17 ZIC2 FOSL1 GATA3 ZNF366 PATZ1 FOS | CYP3AP2 CYP3A5 CYP3A7 CYP3A7-CYP3A51P | |
GH07I099742 | Enhancer | 1 | ENCODE dbSUPER | 0.4 | -7.6 | -7623 | 0.1 | ELF3 FOXA2 ARID4B THRB RAD21 RARA YY1 CREM MIXL1 RXRA | CYP3A7 CYP3A7-CYP3A51P CYP3AP2 | |
GH07I099728 | Enhancer | 1 | ENCODE dbSUPER | 0.4 | +5.5 | 5547 | 3.1 | PKNOX1 FOXA2 ARID4B FEZF1 ZBTB40 RAD21 ATF7 HMG20B USF2 CEBPB | CYP3A5 ZSCAN25 ZKSCAN5 PIR41599 CYP3A7 CYP3A7-CYP3A51P |
- Top Transcription factor binding sites by QIAGEN in the CYP3A7 gene promoter:
Regulatory Element Products
Genomic Locations for CYP3A7 Gene
- chr7:99,705,037-99,735,200
- (GRCh38/hg38)
- Size:
- 30,164 bases
- Orientation:
- Minus strand
- chr7:99,302,660-99,332,819
- (GRCh37/hg19)
Genomic View for CYP3A7 Gene
- Cytogenetic band:
-
- 7q22.1 by Ensembl
- 7q22.1 by Entrez Gene
- 7q22.1 by HGNC


RefSeq DNA sequence for CYP3A7 Gene
Proteins for CYP3A7 Gene
-
Protein details for CYP3A7 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P24462-CP3A7_HUMAN
- Recommended name:
- Cytochrome P450 3A7
- Protein Accession:
- P24462
- A4D288
- Q9H241
Protein attributes for CYP3A7 Gene
- Size:
- 503 amino acids
- Molecular mass:
- 57526 Da
- Cofactor:
- Name=heme; Xref=ChEBI:CHEBI:30413;
- Quaternary structure:
- No Data Available
Protein Expression for CYP3A7 Gene
Selected DME Specific Peptides for CYP3A7 Gene
- P24462:
-
- LAVETWLLLAV
- VLVKECYSVFTN
- PGPTPLP
- LSFIIYEL
- PCKETQIPLK
- EEWKRIR
- SVFTNRR
- PNKAPPTYD
- RVDFLQLM
- ALVRVLQNF
- LLSPTFT
- LSPTFTSG
- PTFTSGK
- NIDPYIY
- DFLQLMIDSQ
- KVQKEID
- PERFSKKN
Post-translational modifications for CYP3A7 Gene
Other Protein References for CYP3A7 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CYP3A7
- Novus Biologicals Antibodies for CYP3A7
-
Abcam antibodies for CYP3A7
-
Cloud-Clone Corp. Antibodies for CYP3A7
- Invitrogen Antibodies for CYP3A7
- GeneTex CYP3A7 antibody for CYP3A7
-
Santa Cruz Biotechnology (SCBT) Antibodies for CYP3A7
Protein Products
-
OriGene Purified Proteins for CYP3A7
- Search Origene for MassSpec and Protein Over-expression Lysates for CYP3A7
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-
Cloud-Clone Corp. Proteins for CYP3A7
- Search GeneTex for Proteins for CYP3A7
-
Abcam proteins for CYP3A7
Assay Products
-
Cloud-Clone Corp. Assay Kits for CYP3A7
- antibodies-online: Search results for 3 available CYP3A7 Elisa Kits ranked by validation data
- Compare Top CYP3A7 Elisa Kits
-
Recommended
Domains & Families for CYP3A7 Gene
Gene Families for CYP3A7 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted membrane proteins
Protein Domains for CYP3A7 Gene
Suggested Antigen Peptide Sequences for CYP3A7 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P24462- Family:
-
- Belongs to the cytochrome P450 family.
Function for CYP3A7 Gene
Molecular function for CYP3A7 Gene
- GENATLAS Biochemistry:
- cytochrome P450,family III,polypeptide 7 (niphedipine oxidase);see CYP3A@
- UniProtKB/Swiss-Prot CatalyticActivity:
- RH + [reduced NADPH--hemoprotein reductase] + O(2) = ROH + [oxidized NADPH--hemoprotein reductase] + H(2)O.
- UniProtKB/Swiss-Prot Function:
- Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
- UniProtKB/Swiss-Prot Induction:
- P450 can be induced to high levels in liver and other tissues by various foreign compounds, including drugs, pesticides, and carcinogens.
Enzyme Numbers (IUBMB) for CYP3A7 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004497 | monooxygenase activity | ISS | -- |
GO:0005506 | iron ion binding | IEA | -- |
GO:0008395 | steroid hydroxylase activity | IDA | 14559847 |
GO:0016491 | oxidoreductase activity | IEA | -- |
GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEA | -- |
Phenotypes for CYP3A7 Gene
- MGI mutant phenotypes for CYP3A7:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for CYP3A7:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CYP3A7
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CYP3A7 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CYP3A7 gene
- Search ViGene Biosciences for CYP3A7
CRISPR Products
-
OriGene CRISPR knockouts for CYP3A7
- genomics-online: gRNA clones - Search results for 49 available CYP3A7 gene related products
- Overview of 49 available CYP3A7 gene related products
- Applied Biological Materials CRISPR for CYP3A7
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CYP3A7
- GenScript: Design CRISPR guide RNA sequences for CYP3A7
miRNA Products
- Search ViGene Biosciences for CYP3A7
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CYP3A7
- Browse OriGene Inhibitory RNA Products For CYP3A7
- genomics-online: shRNA clones - Search results for 49 available CYP3A7 gene related products
- Overview of 49 available CYP3A7 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CYP3A7 gene
Clone Products
- Sino Biological Human cDNA Clone for CYP3A7
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CYP3A7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CYP3A7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for CYP3A7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
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Horizon Cell Lines for CYP3A7
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ViGene Biosciences adenoviral particle packaged cDNA for CYP3A7 gene
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No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for CYP3A7 Gene
Localization for CYP3A7 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CYP3A7 Gene
- Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
- Cytosol (1)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005783 | endoplasmic reticulum | IEA | -- |
GO:0005789 | endoplasmic reticulum membrane | TAS | -- |
GO:0016020 | membrane | IEA | -- |
GO:0031090 | organelle membrane | IEA | -- |
GO:0043231 | intracellular membrane-bounded organelle | IEA | -- |
Pathways & Interactions for CYP3A7 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Cytochrome P450 - arranged by substrate type |
.39
|
|
2 | Drug metabolism - cytochrome P450 | ||
3 | Metabolism |
.37
|
|
4 | Phenytoin Pathway, Pharmacokinetics | ||
5 | Steroid hormone biosynthesis |
Pathways by source for CYP3A7 Gene
2 BioSystems pathways for CYP3A7 Gene
5 Reactome pathways for CYP3A7 Gene
2 PharmGKB pathways for CYP3A7 Gene
4 KEGG pathways for CYP3A7 Gene
2 GeneGo (Thomson Reuters) pathways for CYP3A7 Gene
Interacting Proteins for CYP3A7 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0002933 | lipid hydroxylation | IDA | 14559847 |
GO:0006805 | xenobiotic metabolic process | TAS | -- |
GO:0008202 | steroid metabolic process | IDA | 14559847 |
GO:0055114 | oxidation-reduction process | IEA | -- |
No data available for SIGNOR curated interactions for CYP3A7 Gene
Drugs & Compounds for CYP3A7 Gene
(179) Drugs for CYP3A7 Gene - From: DrugBank, ApexBio, DGIdb, FDA Approved Drugs, HMDB, and Novoseek
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Docetaxel | Approved May 1996, Investigational | Pharma | Enzyme, substrate | Microtubulin disassembly inhibitor, Tubulin and VEGF inhibitor, Taxanes | 2040 | |
Clarithromycin | Approved | Pharma | Enzyme, substrate, inhibitor | 312 | ||
Carbamazepine | Approved, Investigational | Pharma | Enzyme, substrate | 134 | ||
Dexamethasone | Approved, Investigational, Vet_approved | Pharma | Agonist, Enzyme, substrate, inducer | 2314 | ||
Midazolam | Approved, Illicit | Pharma | Enzyme, substrate, inhibitor | 806 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
11,12,15-THETA |
|
|
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11,12-Epoxyeicosatrienoic acid |
|
81276-02-0 |
|
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11,14,15-THETA |
|
|
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11H-14,15-EETA |
|
219535-29-2 |
|
|||
12,13-EpOME |
|
|
(3) ApexBio Compounds for CYP3A7 Gene
Compound | Action | Cas Number |
---|---|---|
Clarithromycin | 81103-11-9 | |
Cobicistat (GS-9350) | Selective CYP3A inhibitor | 1004316-88-4 |
Dafadine-A | DAF-9 cytochrome P450 inhibitor | 1065506-69-5 |
Transcripts for CYP3A7 Gene
mRNA/cDNA for CYP3A7 Gene
- (1) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (85) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CYP3A7 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CYP3A7
- genomics-online: gRNA clones - Search results for 49 available CYP3A7 gene related products
- Overview of 49 available CYP3A7 gene related products
- Applied Biological Materials CRISPR for CYP3A7
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CYP3A7
- GenScript: Design CRISPR guide RNA sequences for CYP3A7
miRNA Products
- Search ViGene Biosciences for CYP3A7
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CYP3A7
- Browse OriGene Inhibitory RNA Products For CYP3A7
- genomics-online: shRNA clones - Search results for 49 available CYP3A7 gene related products
- Overview of 49 available CYP3A7 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CYP3A7 gene
Clone Products
- Sino Biological Human cDNA Clone for CYP3A7
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CYP3A7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CYP3A7
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for CYP3A7
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for CYP3A7 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Liver (Hepatobiliary System)
- Epithelial Cells (Uncategorized)
-
Spleen (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for CYP3A7 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CYP3A7 Gene
NURSA nuclear receptor signaling pathways regulating expression of CYP3A7 Gene:
CYP3A7SOURCE GeneReport for Unigene cluster for CYP3A7 Gene:
Hs.111944Evidence on tissue expression from TISSUES for CYP3A7 Gene
- Liver(3.5)
Primer Products
-
OriGene qPCR primer pairs and template standards for CYP3A7
-
OriGene qPCR primer pairs for CYP3A7
- genomics-online: primer clones - Search results for 49 available CYP3A7 gene related products
- Overview of 49 available CYP3A7 gene related products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CYP3A7 Gene
Orthologs for CYP3A7 Gene
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | LOC100608616 33 |
|
||
CYP3A67 34 |
|
OneToOne | |||
mouse (Mus musculus) |
Mammalia | Cyp3a13 33 16 34 |
|
||
Cyp3a11 34 |
|
ManyToMany | |||
Cyp3a41a 34 |
|
ManyToMany | |||
Cyp3a41b 34 |
|
ManyToMany | |||
Cyp3a16 34 |
|
ManyToMany | |||
Cyp3a25 34 |
|
ManyToMany | |||
Cyp3a44 34 |
|
ManyToMany | |||
Cyp3a57 34 |
|
ManyToMany | |||
Cyp3a59 34 |
|
ManyToMany | |||
rat (Rattus norvegicus) |
Mammalia | Cyp3a9 33 |
|
||
dog (Canis familiaris) |
Mammalia | CYP3A12 34 |
|
ManyToMany | |
CYP3A26 34 |
|
ManyToMany | |||
-- 34 |
|
ManyToMany | |||
-- 34 |
|
ManyToMany | |||
cow (Bos Taurus) |
Mammalia | -- 34 |
|
ManyToMany | |
CYP3A5 34 34 |
|
ManyToMany | |||
oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
-- 34 |
|
ManyToMany | |||
-- 34 |
|
ManyToMany | |||
-- 34 |
|
ManyToMany | |||
platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
ManyToMany | |
-- 34 |
|
ManyToMany | |||
-- 34 |
|
ManyToMany | |||
chicken (Gallus gallus) |
Aves | CYP3A7 33 |
|
||
CYP3A37 34 |
|
OneToMany | |||
lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
ManyToMany | |
-- 34 |
|
ManyToMany | |||
tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100487665 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | cyp3a65 33 34 |
|
||
cyp3c1l2 34 |
|
ManyToMany | |||
cyp3c1 34 |
|
ManyToMany | |||
cyp3c4 34 |
|
ManyToMany | |||
si:dkey-21n8.3 34 |
|
ManyToMany | |||
fruit fly (Drosophila melanogaster) |
Insecta | Cyp6a14 35 |
|
|
|
Cyp6a23 35 |
|
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Cyp6d4 35 |
|
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Cyp6g1 35 |
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Cyp6a17 35 |
|
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Cyp6a13 35 |
|
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Cyp6a20 35 |
|
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Cyp6v1 35 |
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Cyp9f2 35 |
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Cyp6a18 35 |
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Cyp6a2 35 |
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Cyp6g2 35 |
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Cyp9b2 35 |
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Cyp6a19 35 |
|
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Cyp6a22 35 |
|
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Cyp6a8 35 |
|
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Cyp6a9 35 |
|
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Cyp6w1 35 |
|
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Cyp9c1 35 |
|
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Cyp6a21 35 |
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Cyp9b1 35 |
|
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Cyp9h1 35 |
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Cyp28d1 35 |
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Cyp28d2 35 |
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Cyp6d2 35 |
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Cyp6t3 35 |
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Cyp6u1 35 |
|
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Cyp28a5 35 |
|
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Cyp28c1 35 |
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Cyp309a2 35 |
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Cyp313a2 35 |
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Cyp6t1 35 |
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Cyp309a1 35 |
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Cyp317a1 35 |
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worm (Caenorhabditis elegans) |
Secernentea | C36A4.1 35 |
|
|
|
F14F7.2 35 |
|
|
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C36A4.2 35 |
|
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F14F7.3 35 |
|
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T10B9.5 35 |
|
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T10B9.7 35 |
|
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T10B9.8 35 |
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T10B9.1 35 |
|
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T10B9.2 35 |
|
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|||
T10B9.3 35 |
|
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|||
C36A4.6 35 |
|
|
|||
F42A6.4 35 |
|
|
|||
K06G5.2 35 |
|
|
|||
ZK1320.4 35 |
|
|
|||
rice (Oryza sativa) |
Liliopsida | Os02g0221900 33 |
|
- Species where no ortholog for CYP3A7 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CYP3A7 Gene
Paralogs for CYP3A7 Gene
(10) SIMAP similar genes for CYP3A7 Gene using alignment to 3 proteins:
Variants for CYP3A7 Gene
SNP ID | Clin | Chr 07 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000189515 | -- | 99,723,701(-) | A/T | intron_variant | |
rs1000318792 | -- | 99,735,367(-) | T/C | upstream_transcript_variant | |
rs1000472813 | -- | 99,722,816(-) | A/G | intron_variant | |
rs1000781448 | -- | 99,716,579(-) | G/C | intron_variant | |
rs1000916923 | -- | 99,716,245(-) | C/A | intron_variant |
Additional Variant Information for CYP3A7 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CYP3A7 Gene
Disorders for CYP3A7 Gene
Additional Disease Information for CYP3A7
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for CYP3A7 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CYP3A7 Gene
Publications for CYP3A7 Gene
- Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women. (PMID: 19424794) MARIE-GENICA Consortium on Genetic Susceptibility for Menopausal Hormone Therapy Related Breast Cancer Risk (Breast cancer research and treatment 2010) 3 22 44 58
- Identification of a null allele of cytochrome P450 3A7: CYP3A7 polymorphism in a Korean population. (PMID: 19585271) Lee SS … Shin JG (Molecular biology reports 2010) 3 22 44 58
- Association of CYP3A7*1C and serum dehydroepiandrosterone sulfate levels in women with polycystic ovary syndrome. (PMID: 18445661) Goodarzi MO … Azziz R (The Journal of clinical endocrinology and metabolism 2008) 3 22 44 58
- CYP3A7, CYP3A5, CYP3A4, and ABCB1 genetic polymorphisms, cyclosporine concentration, and dose requirement in transplant recipients. (PMID: 18978522) Crettol S … Eap CB (Therapeutic drug monitoring 2008) 3 22 44 58
- Screening for SNPs and haplotypes in the CYP3A7 gene in Chinese populations. (PMID: 17559345) Du J … He L (Pharmacogenomics 2007) 3 22 44 58
Products for CYP3A7 Gene
- Browse R&D Systems for Antibodies
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- Custom Antibody ServicesOriGene Antibodies for CYP3A7
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CYP3A7
- Search Origene for MassSpec and Protein Over-expression Lysates for CYP3A7
- Origene Custom Protein Services for CYP3A7
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CYP3A7
- Browse OriGene Inhibitory RNA Products For CYP3A7
- OriGene qPCR primer pairs and template standards for CYP3A7
- OriGene qPCR primer pairs for CYP3A7
- OriGene CRISPR knockouts for CYP3A7
- OriGene ORF clones in human for CYP3A7
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CYP3A7
- GenScript: Next-day shipping of latest version cDNA ORF clones for CYP3A7 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CYP3A7
- GenScript Custom Assay Services for CYP3A7
- GenScript Custom overexpressing Cell Line Services for CYP3A7
- GenScript: Design CRISPR guide RNA sequences for CYP3A7
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CYP3A7
- Sino Biological Human cDNA Clone for CYP3A7
- Browse Sino Biological Cell Lysates
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- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for CYP3A7
- Novus Biologicals proteins and lysates for CYP3A7
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for CYP3A7
- Abcam proteins for CYP3A7
- Find your target
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- Cloud-Clone Corp. Antibodies for CYP3A7
- Cloud-Clone Corp. Proteins for CYP3A7
- Cloud-Clone Corp. Assay Kits for CYP3A7
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for CYP3A7
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for CYP3A7
- Cyagen custom Knockout/knockin (KOKI) mouse models for CYP3A7
- VectorBuilder custom plasmid, inducible vectors for CYP3A7
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CYP3A7
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 52 available CYP3A7 Antibodies ranked by validation data
- Compare Top CYP3A7 Antibodies
- antibodies-online: Search results for 3 available CYP3A7 Elisa Kits ranked by validation data
- Compare Top CYP3A7 Elisa Kits
- Recommended
- antibodies-online: Search results for 5 available CYP3A7 Proteins ranked by validation data
- Compare Top CYP3A7 Proteins
- GeneTex CYP3A7 antibody for CYP3A7
- Search GeneTex for Proteins for CYP3A7
- ViGene Biosciences adenoviral particle packaged cDNA for CYP3A7 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CYP3A7 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CYP3A7 gene
- Search ViGene Biosciences for CYP3A7
- Santa Cruz Biotechnology (SCBT) Antibodies for CYP3A7
- Search Santa Cruz Biotechnology (SCBT) for CYP3A7 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CYP3A7
- Horizon Cell Lines for CYP3A7
- genomics-online: cdna clones - Search results for 49 available CYP3A7 gene related products
- Overview of 49 available CYP3A7 gene related products
- orf clones - Search results for 49 available CYP3A7 gene related products
- Overview of 49 available CYP3A7 gene related products
- genomics-online: gRNA clones - Search results for 49 available CYP3A7 gene related products
- Overview of 49 available CYP3A7 gene related products
- genomics-online: primer clones - Search results for 49 available CYP3A7 gene related products
- Overview of 49 available CYP3A7 gene related products
- genomics-online: shRNA clones - Search results for 49 available CYP3A7 gene related products
- Overview of 49 available CYP3A7 gene related products
Sources for CYP3A7 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
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- (114) diseasecard
- (115) NIH Rare Diseases
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- (133) ENCODE
- (134) ProSci
- (135) Horizon
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- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
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- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew