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CYP3A43 Gene

protein-coding   GIFtS: 59

GC07P099426
cytochrome P450, family 3, subfamily A, polypeptide 43
(Previous names: cytochrome P450, subfamily IIIA, polypeptide 43 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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Aliases &
Descriptions
for CYP3A43 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases & Descriptions
cytochrome P450, family 3, subfamily A, polypeptide 431 2     cytochrome P450 polypeptide 432
cytochrome P450, subfamily IIIA, polypeptide 431 2     MGC1193162
MGC1193152     EC 1.14.14.13
cytochrome P450 3A432     

External Ids:    HGNC: 174501   Entrez Gene: 648162   Ensembl: ENSG000000214617   UniProtKB: Q9HB553   

Search outside databases for aliases for CYP3A43 gene

Previous GC identifers: GC07P097960 GC07P099023 GC07P099037 GC07P099070 GC07P099263

Summaries
for CYP3A43 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  User Feedback		 Entrez Gene summary for CYP3A43:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and
other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some
drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This
gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in
three transcript variants encoding different isoforms. (provided by RefSeq)

UniProtKB/Swiss-Prot: CP343_HUMAN, Q9HB55
Function: Exhibits low testosterone 6-beta-hydroxylase activity

Genomic Views
for CYP3A43 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences)
About This Section

  User Feedback		 Regulatory elements:
"" SABiosciences Regulatory transcription factor binding sites in the CYP3A43 gene upstream (promoter) region "":
GATA-1   C/EBPalpha   CHOP-10   PPAR-gamma1   PPAR-gamma2   

Epigenetics:
"" Search SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for CYP3A43 ""

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q21.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q21.1

CYP3A43 Gene in genomic location: bands according to Ensembl, locations according to "" (and/or Entrez Gene and/or Ensembl if different)
""

GeneLoc gene densities for chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P099426:  view genomic region     (about GC identifiers)

Start:
 99,425,636 bp from pter
End:
 99,464,173 bp from pter
Size:
 38,538 bases
Orientation:
 plus strand

1 alternative location:
Chr7+,CRA_TCAG 98,785,456-98,823,992     
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NT_079595.2  

Proteins
for CYP3A43 gene

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
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  User Feedback		 UniProtKB/Swiss-Prot: CP343_HUMAN, Q9HB55 (See protein sequence)
Recommended Name: Cytochrome P450 3A43  
Size: 503 amino acids; 57670 Da
Cofactor: Heme group (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral
membrane protein
Secondary accessions: Q9HB52 Q9HB53 Q9HB54 Q9HB57
Alternative splicing: 5 isoforms:  Q9HB55-1   Q9HB55-2   Q9HB55-3   Q9HB55-4   Q9HB55-5   (Additional isoforms seem to exist)

REFSEQ proteins (3 alternative transcripts): 
NP_073731.1  NP_476436.1  NP_476437.1  


ENSEMBL proteins: 
ENSP00000222382 ENSP00000346887 ENSP00000415221 ENSP00000416581 ENSP00000405557 ENSP00000401521 
ENSP00000400316 ENSP00000411653 ENSP00000312110 ENSP00000368975 ENSP00000397332 ENSP00000345351 


Human Recombinant Proteins 
""Browse Purified and Recombinant Proteins at Millipore
""Sigma-Aldrich AQUA Peptides for CYP3A43
"" Browse R&D Systems for human recombinant proteins
""Enzo Life Sciences proteins for CYP3A43
""HuPro® and/or Recombinant Proteins from Abnova for CYP3A43 ""
""Browse Origene full length recombinant human proteins expressed in human HEK293 cells
""Novus Biologicals Protein for CYP3A43  ""
""Browse Sino Biological Recombinant Proteins  ""

5 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005783 endoplasmic reticulum IEA--
GO:0005789 endoplasmic reticulum membrane IEA--
GO:0005792 microsome IEA--
GO:0016020 membrane IEA--
GO:0019898 extrinsic to membrane ----
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"" CYP3A43 for ontologies           About GeneDecksing



Antibodies for CYP3A43: 
""Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
""Sigma-Aldrich Antibodies for CYP3A43
"" Browse R&D Systems for Antibodies
""Monoclonal and Polyclonal Antibodies from Abnova (CYP3A43)
""Browse Origene Antibodies ""
""Novus Biologicals Antibody for CYP3A43
""Browse antibodies at Epitomics

Assays for CYP3A43: 
""Browse Kits and Assays available from Millipore
""Browse ELISAs at Sigma-Aldrich
"" Browse R&D Systems for biochemical assays
""Enzo Life Sciences assays for CYP3A43

Protein Domains/
Families
for CYP3A43 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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5 InterPro domains/families:
 IPR008072 Cyt_P450_E_CYP3A
 IPR001128 Cyt_P450
 IPR017973 Cyt_P450_C
 IPR017972 Cyt_P450_CS
 IPR002402 Cyt_P450_E_grp-II

Graphical View of Domain Structure for InterPro Entry Q9HB55

ProtoNet protein and cluster: Q9HB55

2 Blocks protein families:
IPB002401 E-class P450 group I signature
IPB008072 CYP3A P450 family signature


UniProtKB/Swiss-Prot: CP343_HUMAN, Q9HB55
Similarity: Belongs to the cytochrome P450 family

Gene Function
for CYP3A43 gene

(According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
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Inhib.
RNA:		""Browse for Gene Knock-down Tools from Millipore
""Abnova Chimera RNAi Products for Gene knock-down (CYP3A43)
"" Origene 29mer shRNA kits in GFP-retroviral vector (see all 3): CYP3A43
Origene shRNA RFP (see all 3): CYP3A43
Origene basic RS shRNA (see all 3): CYP3A43

""Applied Biosystems Silencer® siRNAs for CYP3A43
""Sigma-Aldrich siRNA Panels and siRNA for CYP3A43
Sigma-Aldrich shRNA for CYP3A43
Explore Sigma-Aldrich super-pooled esiRNAs
Clones:""Browse Clones for the Expression of Recombinant Proteins Available from Millipore
""Browse iPSC Reprogramming Factors at Sigma-Aldrich
"" Origene GFP tagged cDNA clones in CMV expression vector (see all 3): CYP3A43
Origene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): CYP3A43
Origene untagged cDNA clones in CMV expression vector (see all 3): CYP3A43
""Browse Sino Biological Human cDNA Clones  ""

UniProtKB/Swiss-Prot: CP343_HUMAN, Q9HB55
Function: Exhibits low testosterone 6-beta-hydroxylase activity
Catalytic activity: RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O
Induction: By rifampicin
Enzyme Number (IUBMB): EC 1.14.14.1 

5/6 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 6 ):

GO IDQualified GO termEvidencePubMed IDs
GO:0004497 monooxygenase activity ISS--
GO:0005506 iron ion binding ----
GO:0009055 electron carrier activity IEA--
GO:0020037 heme binding IEA--
GO:0046872 metal ion binding IEA--
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"" CYP3A43 for ontologies           About GeneDecksing

Pathways & Interactions
for CYP3A43 gene

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
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"" CYP3A43 for pathways           About GeneDecksing

5 "" Sigma-Aldrich "Your Favorite Gene" Pathways for  CYP3A43  (Your Favorite Gene powered by Ingenuity)
  ""  Linoleic Acid Metabolism
Arachidonic Acid Metabolism
Tryptophan Metabolism
Fatty Acid Metabolism
Metabolism of Xenobiotics by Cytochrome P450

5/7 "" Kegg Pathways  (Kegg details for CYP3A43) (see all 7 ):
  ""  hsa00140 Steroid hormone biosynthesis
hsa00591 Linoleic acid metabolism
hsa00830 Retinol metabolism
hsa00980 Metabolism of xenobiotics by cytochrome P450
hsa00982 Drug metabolism - cytochrome P450

"" Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CYP3A43

5/48 Interacting proteins for CYP3A43 (ENSP000002223823) via UniProtKB, MINT, and/or STRING (see all 48 ) ""
InteractantInteraction Details
GeneCardExternal ID(s)
EPHX1ENSP000003558023STRING: ENSP00000355802
GSTA1ENSP000003356203STRING: ENSP00000335620
GSTA3ENSP000002111223STRING: ENSP00000211122
GSTA4ENSP000003600023STRING: ENSP00000360002
GSTA5ENSP000003600283STRING: ENSP00000360028
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1 Gene Ontology (GO) biological process term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0055114 oxidation reduction IEA--
About this table

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Drugs & Compounds
for CYP3A43 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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"" CYP3A43 for compounds           About GeneDecksing

"" Enzo Life Sciences drugs & compounds for CYP3A43
""Browse Small Molecules at Sigma-Aldrich

"" Browse Tocris compounds for CYP3A43
3 ""Novoseek chemical compound relationships for CYP3A43 gene
Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
midazolam 1.64 1 20041831 (1)
rifampicin 1.54 1 11266076 (1)
retinoic acid 1.09 1 16430309 (1)
About this table


Transcripts
for CYP3A43 gene

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
Expression Assays from Applied Biosystems)
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Inhib.
RNA:		""Browse for Gene Knock-down Tools from Millipore
""Abnova Chimera RNAi Products for Gene knock-down (CYP3A43)
""Applied Biosystems Silencer® siRNAs:  NM_022820  NM_057095  NM_057096  
"" Origene 29mer shRNA kits in GFP-retroviral vector (see all 3): CYP3A43
Origene shRNA RFP (see all 3): CYP3A43
Origene basic RS shRNA (see all 3): CYP3A43

""Sigma-Aldrich siRNA Panels and siRNA for CYP3A43
Sigma-Aldrich shRNA for CYP3A43
Explore Sigma-Aldrich super-pooled esiRNAs

microRNA:""Search SABiosciences for microRNAs that regulate CYP3A43: ""
Assays:  ""Applied Biosystems TaqMan® Gene Expression Assays:  
NM_022820  NM_057095  NM_057096  


Clones:"" Origene GFP tagged cDNA clones in CMV expression vector (see all 3): CYP3A43
Origene Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): CYP3A43
Origene untagged cDNA clones in CMV expression vector (see all 3): CYP3A43
Primers:"" Origene genome-wide validated SYBR primer pairs: CYP3A43
""SABiosciences RT2 qPCR Primer Assay for CYP3A43: PPH01261A ""

REFSEQ mRNAs for CYP3A43 gene (3 alternative transcripts): 

NM_022820.3  NM_057095.1  NM_057096.2  

Additional cDNA sequence: 

AF280108.1 AF280109.1 AF280110.1 AF280111.1 AF280112.1 AF280113.1 AF319634.1 AF337813.1 
AY390423.1 AY390424.1 AY390425.1 AY390426.1 BC100981.3 BC100982.3 

3 DOTS entries:

DT.104214  DT.100745110  DT.99960925 

20 AceView cDNA sequences:

AF280111 BX092633 AF280109 AF319634 AF280108 AY390425 NM_057096 AY390423 
AF280112 AY390424 NM_057095 NM_022820 AW662829 AY390426 BX951468 AA417369 
AF280110 AF280113 AA416822 AF337813 

"" highest scoring ESTs for CYP3A43:

AA417369 AF280108 AF280109 AF280110 AF280111 AF280113 AF319634 AF337813 AY390423 AY390424 

Unigene Cluster for CYP3A43:

Cytochrome P450, family 3, subfamily A, polypeptide 43
Hs.306220  [show with all ESTs]
Unigene Representative Sequence: NM_022820


GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CYP3A43 (see all 6 )

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b
SP1:                          -                       -                                                               
SP2:                          -                       -                 -                                             
SP3:                          -                       -                 -                                             
SP4:                          -                       -                 -                             -               
SP5:                                      -     -     -     -     -     -                                             

About this scheme

ECgene alternative splicing isoforms for CYP3A43

18 Ensembl transcripts including schematic representations:
ENST00000222382  ENST00000472352  ENST00000354829  ENST00000436834  ENST00000417625  ENST00000463915  
ENST00000444905  ENST00000415413  ENST00000477658  ENST00000495115  ENST00000433277  ENST00000491648  
ENST00000481362  ENST00000434806  ENST00000312017  ENST00000379654  ENST00000421837  ENST00000342499  

Expression
for CYP3A43 gene

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
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CYP3A43 expression in normal and diseased human tissues

"" Applied Biosystems TaqMan ® Gene Expression Assays for CYP3A43

1""  / 2""  / 3""

8 probe-sets matching CYP3A43 gene

Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
207773_x_at2, 3 U133-A 1 1.00 1.00 -- -- NM_022820 0.60 1.00 0.82 1
211440_x_at2, 3 U133-A 1 1.00 1.00 -- -- AF280110 0.80 1.00 0.91 1
211442_x_at2, 3 U133-A 4 1.00 0.93 -- -- AF280111 0.80 1.00 0.91 1
211441_x_at2, 3 U133-A 4 0.91 0.93 -- -- AF280113 0.80 1.00 0.91 1
207773_x_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
211440_x_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
211442_x_at2 U133Plus2 4 1.00 0.93 -- -- -- -- -- -- --
211441_x_at2 U133Plus2 4 0.91 0.93 -- -- -- -- -- -- --
About this table
Data from Genenote  (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: TTCCATTTGT

SOURCE GeneReport for Unigene cluster: Hs.306220

UniProtKB/Swiss-Prot: CP343_HUMAN, Q9HB55
Tissue specificity: Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and
fetal skeletal muscle

Primers:"" Origene genome-wide validated SYBR primer pairs: CYP3A43 ""
""SABiosciences RT2 qPCR Primer Assay for CYP3A43: PPH01261A ""

Orthologs
for CYP3A43 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for CYP3A43 gene from 5/7 species (see all 7 )
Organism Gene Locus Description Human
Similarity		 NCBI accessions
chimpanzee
(Pan troglodytes)		 CYP3A431   -- cytochrome P450 subfamily IIIA polypeptide 43 99.14(n)
99.01(a)		 472456  XM_527830.2  XP_527830.2 
rat
(Rattus norvegicus)		 Cyp3a181   -- cytochrome P450, 3a18 73.98(n)
64.39(a)		 252931  NM_145782.1  NP_665725.1 
mouse
(Mus musculus)		 Cyp3a251, 5 5 (85.00 cM)5
 cytochrome P450, family 3, subfamily a, polypeptide more1, 5 74.37(n)1
66.53(a)1		 563881  NM_019792.11  NP_062766.11 
 AF2049595  AI3270085  (see all 9)
zebrafish
(Danio rerio)		 BC052130.12   --   -- 72.92(n)  BC052130.1 
fruit fly
(Drosophila melanogaster)		 Cyp6g13 2 48E7 DDT resistance cytochrome P450 33(a)
(best of 34)		   --
About this table        Species with no ortholog for CYP3A43

ENSEMBL Gene Tree for CYP3A43

Paralogs
for CYP3A43 gene

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
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Paralogs for CYP3A43 gene
CYP4F222  CYP4F112  CYP4F22  CYP4F32  CYP4F82  CYP46A12  LOC3885142  CYP4B12  
CYP3A52  CYP4X12  TBXAS12  CYP3A42  CYP3A72  CYP4V22  CYP4A222  CYP4A112  
CYP4Z12  CYP4F122  

"" CYP3A43 for paralogs           About GeneDecksing


Genomic Variants
for CYP3A43 gene

(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
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  User Feedback		UniProtKB/Swiss-Prot: CP343_HUMAN, Q9HB55
Polymorphism: At protein level, three alleles are known: CYP3A43*1, CYP3A43*2 and CYP3A43*3. The sequence shown is that
of CYP3A43*1, which is the most frequent allele. The allele CYP3A43*2 is likely to be non-functional


10/282 NCBI SNPs in CYP3A43 are shown (see all 282 )
(Click "" for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 55)
ABGenomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 7 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
------------
""
rs14031951,2
C,F,H94060259(+) CATGGA/GGTATC 3 -- ng51""6Minor allele frequency- G:0.08NS EA 684""
""
rs454837931,2
C,F94061413(+) TAAGGA/GCAGCC 3 -- ng51""2Minor allele frequency- G:0.01--192""
--
rs456007361,2
C,F94061543(+) ATATCG/ACTGTT 3 -- ng51""2Minor allele frequency- A:0.01--192""
--
rs455580321,2
C,F99434083(+) ATGGGA/GCCCAT 6 T A ref1 mis1""2Minor allele frequency- G:0.03--180""
""
rs171619831,2
C,F99463818(+) ACTACA/GAAGCA 3 -- ut31 ese3""13Minor allele frequency- G:0.11NA NS EA WA 1036""
--
rs455859361,2
C,F94061426(+) AATTAT/GTTGCC 3 -- ng51""2Minor allele frequency- G:0.01--192""
""
rs454500921,2
C,F99445791(+) TAGATG/TGTCCC 6 M I ref1 mis1""17Minor allele frequency- T:0.02MN WA EA 2910""
--
rs456214311,2
C,F99454482(+) CAGATG/AATCGA 6 /I /M mis1 ref1""2Minor allele frequency- A:0.02--192""
""
rs4737061,2
C,F94060679(-) ACCTCC/TGAGGC 3 -- ng51""10Minor allele frequency- T:0.06NS EA NA WA 892""
""
rs6800551,2
C,F99457605(-) ATTGGG/CTAAAA 6 /P /A ref1 mis1""34Minor allele frequency- C:0.10MN NA NS EA WA 4244""
About this table

HapMap Linkage Disequilibrium images for CYP3A43 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)  ""
Database of Genomic Variants (DGV): 4 variations for CYP3A43
     4 CNVs: 94732 64899 82103 94733

Disorders & Mutations
for CYP3A43 gene

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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"" CYP3A43 for disorders           About GeneDecksing

OMIM: 606534

Locus Specific Mutation Databases: CYP3A43
Human Gene Mutation Database: CYP3A43
Genetic Association Database: CYP3A43
Human Genome Epidemiology Navigator: CYP3A43 (7 documents)

Medical News
for CYP3A43 gene

(Possibly Related Articles in Doctor's Guide)
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  User Feedback		   --

Publications
for CYP3A43 gene

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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  User Feedback		10/21 PubMed articles for CYP3A43 gene (see all 21 ):

Search for CYP3A43 gene

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Search String
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
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Genome Databases showing CYP3A43 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 64816 HGNC: 17450 AceView: CYP3A43 Ensembl:ENSG00000021461 euGenes: HUgn64816
ECgene: CYP3A43 Kegg: 64816 H-InvDB: CYP3A43

Other Databases showing CYP3A43 gene

(According to HUGE)
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Specialized Databases showing CYP3A43 gene

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
Cytochrome P450 Allele Nomenclature Committeehttp://www.cypalleles.ki.se/cyp3a43.htm

Intellectual Property
for CYP3A43 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
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  User Feedback		Patent Information for CYP3A43 gene: ""
Search GeneIP for patents involving CYP3A43

GeneCards and IP: ""
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search


Services
for CYP3A43 gene

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Novus Biologicals,
Epitomics, Sigma-Aldrich, R&D Systems, SABiosciences, Millipore, Abnova,
Clones available from OriGene, Sigma-Aldrich, Sino Biological, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience)
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Products for CYP3A43:
"" TaqMan ® Gene Expression Assays
"" TaqMan ® Genotyping Assays
 "" Free SNP selection tool

""
"" Millipore Custom Antibody & Bulk Services
"" Millipore Preclinical / Clinical Development Services
"" Millipore Immunoassay Services
"" Millipore Target Screening & Profiling Services

""
"" Predesigned and custom siRNAs for CYP3A43"" Antibodies for CYP3A43
"" Explore super-pooled esiRNAs"" Proteins for CYP3A43
"" Lentivirus-delivered shRNAs for CYP3A43"" Browse small molecules at Sigma-Aldrich
"" "Your Favorite Gene" Pathways"" Browse ELISAs at Sigma-Aldrich
"" Browse iPSC Reprogramming Factors at Sigma-Aldrichfeedback


 ""  ""
"" Antibodies  "" Primer Pairs  
"" Cell Culture Products  "" ELISAs  
"" Flow Cytometry Kits  "" Protease Activity Assays & Reagents  
"" Cell Selection/Detection Kits & Reagents  "" ELISA/Assay Development Kits & Reagents  
"" Multiplex/Array Assay Kits & Reagents  "" ELISpot Kits & Development Modules  
"" Recombinant & Natural Proteins  

"" Recombinant Proteins (CYP3A43)
"" Antibodies (CYP3A43)
"" Chimera RNAi (CYP3A43)
"" Custom Service for Mouse Mab
"" Custom Service for Rabbit Pab from Full-length Protein


""""""""
"" Search for Antibodies & Assays

"" Tagged/untagged cDNA clones
"" Validated SYBR primer pairs
"" Purified proteins from HEK293T cells
"" Western blot validated antibodies
"" shRNA in GFP-retroviral vector
"" Custom immunoassay development
"" Search Tocris compounds for CYP3A43
"" Regulatory tfbs in CYP3A43 upstream (promoter) region
"" Search Chromatin IP Primers for CYP3A43
"" Search DNA Methylation qPCR Primer Assays for CYP3A43
"" RT2 qPCR Primer Assay for CYP3A43
"" Search GNC Networks for CYP3A43
"" Search for microRNAs that regulate CYP3A43
""""""""
"" Assays/Drugs/Proteins for CYP3A43
"" Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
"" Novus Tissue Slides
"" Antibodies for CYP3A43
"" Proteins for CYP3A43
"" Browse antibodies at Epitomics
"" Browse Sino Biological Proteins and Antibodies
"" Browse Sino Biological cDNA Clones
"" Antibodies/Proteins Production Services
"" Rabbit Monoclonal Antibody Platform
"" Bulk Purchasing
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