Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CYP2W1 Gene

protein-coding   GIFtS: 54
GCID: GC07P001022

cytochrome P450, family 2, subfamily W, polypeptide 1

 Explore 2 diseases affiliated with
CYP2W1 via our new
 Human Malady Compendium 
Biological research products
for CYP2W1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Cytochrome P450, Family 2, Subfamily W, Polypeptide 11 2     Cytochrome P450 2W12
CYPIIW12 3     EC 1.14.14.-3
FLJ203591     EC 1.14.14.18
MGC342871     EC 1.14.14.58

External Ids:    HGNC: 202431   Entrez Gene: 549052   Ensembl: ENSG000000730677   UniProtKB: Q8TAV33   

Export aliases for CYP2W1 gene to outside databases

Previous GC identifers: GC00U916974 GC07P000796 GC07P000989 GC07P000939


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CYP2W1:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and
other lipids. (provided by RefSeq, Jul 2008)

Gene Wiki entry for CYP2W1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CYP2W1 gene promoter:
         NF-1   NF-1/L   NRSF form 1   Bach2   MIF-1   NRSF form 2   Roaz   HEN1   SRY   Zic1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCYP2W1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CYP2W1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYP2W1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.3   Ensembl cytogenetic band:  7p22.3   HGNC cytogenetic band: 7p22.3

CYP2W1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CYP2W1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P001022:  view genomic region     (about GC identifiers)

Start:
1,022,835 bp from pter      End:
1,029,276 bp from pter
Size:
6,442 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 1,077,465-1,083,884     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CP2W1_HUMAN, Q8TAV3 (See protein sequence)
Recommended Name: Cytochrome P450 2W1  
Size: 490 amino acids; 53844 Da
Cofactor: Heme group (By similarity)
Subcellular location: Membrane; Peripheral membrane protein (Potential). Endoplasmic reticulum membrane (Potential)

Explore the universe of human proteins at neXtProt for CYP2W1: NX_Q8TAV3

4 DME Specific Peptides for CYP2W1 (Q8TAV3)
 EAFLPFS  AGTETTS  PGPRPLP  KIEEVRA 

CYP2W1 Protein expression data from MOPED and PaxDb:    About this image 
Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_060251.2  
ENSEMBL proteins: 
 ENSP00000310149   ENSP00000344178   ENSP00000392581  
Reactome Protein details: Q8TAV3
Human Recombinant Protein Products: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein: CYP2W1
OriGene Protein Over-expression Lysate: CYP2W1
OriGene Custom Protein Services for CYP2W1 
GenScript Custom Purified and Recombinant Proteins Services for CYP2W1
Novus Biologicals CYP2W1 Protein
Novus Biologicals CYP2W1 Lysate
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins
Uscn Proteins for CYP2W1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005789endoplasmic reticulum membrane TAS--


CYP2W1 for ontologies           About GeneDecksing



CYP2W1 Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for CYP2W1 
GenScript Custom Superior Antibodies Services for CYP2W1
Novus Biologicals CYP2W1 Antibodies
Abcam antibodies for CYP2W1 
Uscn Antibodies for CYP2W1
ThermoFisher Antibodies for CYP2W1

Assay Products for CYP2W1: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Immunoassay Development
Browse OriGene Fluorogenic Cell Assay Kits
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for CYP2W1
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for CYP2W1


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CYP2W1 for domains           About GeneDecksing

3 InterPro domains/families:
 IPR001128 Cyt_P450
 IPR017972 Cyt_P450_CS
 IPR002401 Cyt_P450_E_grp-I

Graphical View of Domain Structure for InterPro Entry Q8TAV3

ProtoNet protein and cluster: Q8TAV3

1 Blocks protein family: IPB002401 E-class P450 group I signature

UniProtKB/Swiss-Prot: CP2W1_HUMAN, Q8TAV3
Similarity: Belongs to the cytochrome P450 family


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Enzyme Numbers (IUBMB): EC 1.14.14.12 EC 1.14.14.-1 EC 1.14.14.52

miRNA
Products:
    
Browse 3'-UTR reporter clones for miRNA target validation
Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CYP2W1
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CYP2W1
SwitchGear 3'UTR luciferase reporter plasmidCYP2W1 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CYP2W1
OriGene shRNA RFP: CYP2W1
OriGene siRNA: CYP2W1
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CYP2W1

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for CYP2W1

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2W1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2W1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: CYP2W1 (NM_017781)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CYP2W1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP2W1 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for CYP2W1
Search LifeMap BioReagents cell lines for CYP2W1

In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP2W1

Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004497monooxygenase activity IEA--
GO:0005506iron ion binding IEA--
GO:0009055electron carrier activity IEA--
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA--
GO:0020037heme binding IEA--


CYP2W1 for ontologies           About GeneDecksing


1 GenomeRNAi human phenotype for CYP2W1:
 Increased gamma-H2AX phosphory 


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1Cytochrome P450 - arranged by substrate type
Cytochrome P450 - arranged by substrate type1.00
cytochrome P4500.73
Phase 1 - Functionalization of compounds0.74
2Biological oxidations
Biological oxidations1.00
metapathway biotransformation0.41
3Miscellaneous substrates
Miscellaneous substrates1.00
4Metabolism
Metabolism1.00

Pathway sources
See GeneCards unified pathways
Show all pathways


2 BioSystems Pathways for CYP2W1 
    cytochrome P450
metapathway biotransformation

5        Reactome Pathways for CYP2W1
    Cytochrome P450 - arranged by substrate type
Miscellaneous substrates
Metabolism
Biological oxidations
Phase 1 - Functionalization of compounds



CYP2W1 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CYP2W1

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for CYP2W1 (ENSP000003101494) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CYB5AENSP000003416254STRING: ENSP00000341625
ZBTB26ENSP000003627584STRING: ENSP00000362758
About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006805xenobiotic metabolic process TAS--
GO:0044281small molecule metabolic process TAS--


CYP2W1 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CYP2W1

1 HMDB Compound for CYP2W1    About this table
CompoundSynonyms CAS #PubMed Ids
Heme(protoporphyrinato)iron (see all 19)14875-96-8--
Search CenterWatch for drugs/clinical trials and news about CYP2W1 / CP2W1 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CYP2W1 gene: 
NM_017781.2  

Unigene Cluster for CYP2W1:

Cytochrome P450, family 2, subfamily W, polypeptide 1
Hs.272795  [show with all ESTs]
Unigene Representative Sequence: AK000366
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000308919(uc003sjq.1) ENST00000340150(uc003sjr.1) ENST00000462453
ENST00000468456 ENST00000415893

miRNA
Products:
     
Browse 3'-UTR reporter clones for miRNA target validation
Browse OriGene MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CYP2W1
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CYP2W1
SwitchGear 3'UTR luciferase reporter plasmidCYP2W1 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CYP2W1
OriGene shRNA RFP: CYP2W1
OriGene siRNA: CYP2W1
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CYP2W1
Clone
Products:
     
OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2W1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2W1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: CYP2W1 (NM_017781)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CYP2W1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP2W1 
Primer
Products:
    
OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYP2W1
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CYP2W1
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYP2W1
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYP2W1

Additional cDNA sequence: 

AK000366.1 BC025761.1 

6 DOTS entries:

DT.100751090  DT.97839280  DT.97839281  DT.100751088  DT.97839282  DT.92324190 

24/35 AceView cDNA sequences (see all 35):

BU150425 BM766605 CR599457 BM767876 BM767532 BC025761 CD628619 AL520637 
CD628616 BX439125 CD628614 NM_017781 BI772553 AL561898 CD628608 AK000366 
BM738552 CD628610 AU119534 BX281067 AI925040 CD628617 BP351592 BM743596 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for CYP2W1    About this scheme

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b
SP1:                          -                                   -                                 
SP2:                          -                                                                     
SP3:                                                              -                                 
SP4:                                            -     -           -                                 
SP5:                                                                                                


ECgene alternative splicing isoforms for CYP2W1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CYP2W1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)

About this image
See CYP2W1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CYP2W1

SOURCE GeneReport for Unigene cluster: Hs.272795
    SABiosciences Expression via Pathway-Focused PCR Array including CYP2W1: 
          Drug Metabolism: Phase I Enzymes in human mouse rat

Primer
Products:
OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYP2W1
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CYP2W1
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYP2W1
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYP2W1
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP2W1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for CYP2W1 gene from 4/12 species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
chicken
(Gallus gallus)
Aves CYP2W11 cytochrome P450, family 2, subfamily W, polypeptide more 61.6(n)
55.65(a)
  416454  XM_414762.3  XP_414762.2 
lizard
(Anolis carolinensis)
Reptilia --
--
--
49(a)
47(a)
1 ↔ many
1 ↔ many
GL343385.1(737243-747004)
GL343500.1(560196-574838)
zebrafish
(Danio rerio)
Actinopterygii cyp2k176
cyp2k166
(see all 10)
cytochrome P450, family 2, subfamily K, polypeptid...
cytochrome P450, family 2, subfamily K, polypeptid...
(see all 10)
40(a)
40(a)
(see all 10)
1 ↔ many
1 ↔ many
(see all 10)
3(12503979-12511563)
3(12486340-12502204)
worm
(Caenorhabditis elegans)
Secernentea daf-91 Protein DAF-9 44.07(n)
33.17(a)
  180889  NM_171699.3  NP_741807.2 


ENSEMBL Gene Tree for CYP2W1 (if available)
TreeFam Gene Tree for CYP2W1 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for CYP2W1 gene
CYP2C82  CYP2F12  CYP2A72  CYP2R12  CYP2U12  CYP2J22  CYP2E12  CYP2D62  
CYP2B7P12  CYP2A62  CYP2B62  CYP2C192  CYP2S12  CYP2C92  CYP2C182  CYP2A132  
18/26 SIMAP similar genes for CYP2W1 using alignment to 3 protein entries:     CP2W1_HUMAN (see all proteins) (see all similar genes):
CYP2G1P    CYP2C9    CYP 2C    CYP2S1    CYP2E1    CYP21A/CYP21B fusion gene
CYP2R1    CYP2C8    CYP2C19    CYP2F1    CYP2J2    CYP2A13
CYP2B6    CYP2A7    CYP2C18    CYP2A6    CYP2B    CYP2B7

CYP2W1 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for CYP2W1
PGOHUM00000243186


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/223 NCBI SNPs in CYP2W1 are shown (see all 223    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1882155941,2
--1020880(+) TGAGCC/GAAGAT 1 -- us2k10--------
rs1470091801,2
--1021002(+) CCCAGC/TGCTTT 1 -- us2k10--------
rs1382318661,2
--1021119(+) CGAGGC/TGGGCG 1 -- us2k10--------
rs794692871,2
C,F,--1021122(+) GGCGGG/ACGGAT 1 -- us2k12Minor allele frequency- A:0.11NA EA 240
rs1810120181,2
--1021236(+) TCCCAG/TCTACT 1 -- us2k10--------
rs1843650001,2
--1021242(+) CTACTC/TGGGAG 1 -- us2k10--------
rs624331291,2
--1021259(+) GCAGGA/CGAATC 1 -- us2k10--------
rs1897749191,2
--1021446(+) ATTGCG/TTGAAC 1 -- us2k10--------
rs1811305271,2
--1021577(+) GGTGGC/GAGGAT 1 -- us2k10--------
rs1861105291,2
--1021579(+) TGGGAA/GGATGG 1 -- us2k10--------

HapMap Linkage Disequilibrium report for CYP2W1 (1022835 - 1029276 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for CYP2W1: --
Human Gene Mutation Database (HGMD): CYP2W1

Locus Specific Mutation Databases (LSDB): CYP2W1

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYP2W1
DNA2.0 Custom Variant and Variant Library Synthesis for CYP2W1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CYP2W1 for disorders           About GeneDecksing

2 diseases for CYP2W1:    About MalaCards
cholesterol    colorectal cancer

Human Genome Epidemiology (HuGE) Navigator: CYP2W1 (2 documents)

Export disorders for CYP2W1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for CYP2W1 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with CYP2W1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  2. Metabolomic analysis and identification of a role for the orphan human cytochrome P450 2W1 in selective oxidation of lysophospholipids . (PubMed id 22591743)1 Xiao Y. and Guengerich F.P. (2012)
  3. The expression of CYP2W1: a prognostic marker in colon cancer. (PubMed id 22993331)1 Stenstedt K....Edler D. (2012)
  4. CYP2W1, CYP4F11 and CYP8A1 polymorphisms and interacti on of CYP2W1 genotypes with risk factors in Mexican women with breast cancer. (PubMed id 22631658)1 Cardenas-Rodriguez N....Floriano-Sanchez E. (2012)
  5. Colorectal cancer-specific cytochrome P450 2W1: intra cellular localization, glycosylation, and catalytic activity. (PubMed id 20805301)1 Gomez A....Ingelman-Sundberg M. (2010)
  6. CYP2W1 variant alleles in Caucasians and association of the CYP2W1 G541A (Ala181Thr) polymorphism with increased colorectal cancer r isk. (PubMed id 20602611)1 Gervasini G....AgA_ndez J.A. (2010)
  7. Genetic polymorphisms and haplotype structures of the human CYP2W1 gene in a Japanese population. (PubMed id 17998294)1 Hanzawa Y....Hiratsuka M. (2008)
  8. Expression of CYP2W1 in colon tumors: regulation by gene methylation. (PubMed id 17979506)1 Gomez A....Ingelman-Sundberg M. (2007)
  9. Enzymatic properties of human CYP2W1 expressed in Esc herichia coli. (PubMed id 16677611)1 Yoshioka H....Sakaki T. (2006)
  10. Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1. (PubMed id 16426568)1 Karlgren M....Ingelman-Sundberg M. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 54905 HGNC: 20243 AceView: CYP2W1 Ensembl:ENSG00000073067 euGenes: HUgn54905
ECgene: CYP2W1 H-InvDB: CYP2W1

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for CYP2W1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for CYP2W1 gene:
Search GeneIP for patents involving CYP2W1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section

 
 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
 Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
 Browse OriGene Antibodies   OriGene shRNA RFP for CYP2W1  
 OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CYP2W1   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYP2W1  
 OriGene Protein Over-expression Lysate for CYP2W1   Browse OriGene Fluorogenic Cell Assay Kits  
 OriGene siRNA for CYP2W1   Browse 3'-UTR reporter clones for miRNA target validation  
 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2W1   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2W1  
 Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
 Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
 OriGene Purified Protein for CYP2W1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for CYP2W1   OriGene Custom Protein Services for CYP2W1  
 OriGene Custom Immunoassay Development  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CYP2W1
 QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYP2W1
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYP2W1
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CYP2W1
 QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYP2W1
 QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYP2W1
 GenScript Custom Purified and Recombinant Proteins Services for CYP2W1 GenScript cDNA clones with any tag delivered in your preferred vector for CYP2W1
 GenScript Custom Assay Services for CYP2W1 GenScript Custom Superior Antibodies Services for CYP2W1
 GenScript Custom overexpressing Cell Line Services for CYP2W1 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Regulatory tfbs in CYP2W1 promoter
 Search Chromatin IP Primers for CYP2W1
 RT2 qPCR Primer Assay in human, mouse, rat CYP2W1
 Search GNC Networks for CYP2W1
 SABiosciences PCR Arrays including human, mouse, rat CYP2W1
 Search Tocris compounds for CYP2W1
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological cDNA Clones
 Antibodies/Proteins Production Services
 Rabbit Monoclonal Antibody Platform
 Bulk Purchasing
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 CYP2W1 antibodies
 CYP2W1 proteins
 CYP2W1 lysates
 Antibodies for CYP2W1
 See all of Abcam's Antibodies, Kits and Proteins for CYP2W1
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 CYP2W1 Proteins, Antibodies, CLIAs, and ELISAs
 Search LifeMap BioReagents cell lines for CYP2W1
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP2W1
 SwitchGear 3'UTR luciferase reporter plasmids for CYP2W1
 SwitchGear Promoter luciferase reporter plasmids for CYP2W1
 ThermoFisher Antibodies for CYP2W1
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP2W1
       
GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category
VWF
(GIFTS: 73)
von Willebrand factor
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      CYP2W1 gene at Home site.
hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4