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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CYP2U1 Gene

protein-coding   GIFtS: 55
GCID: GC04P108852

cytochrome P450, family 2, subfamily U, polypeptide 1
 Explore 4 diseases affiliated with
CYP2U1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CYP2U1    

Aliases
for CYP2U1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Cytochrome P450, Family 2, Subfamily U, Polypeptide 11 2     SPG562
SPG491 2     Cytochrome P450 2U12
EC 1.14.14.13 8     Spastic Paraplegia 492
P450TEC2     

External Ids:    HGNC: 205821   Entrez Gene: 1136122   Ensembl: ENSG000001550167   OMIM: 6106705   UniProtKB: Q7Z4493   

Export aliases for CYP2U1 gene to outside databases

Previous GC identifers: GC04P109309 GC04P109210 GC04P109072 GC04P104584


Summaries
for CYP2U1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CYP2U1:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and
other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long
chain fatty acids. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CP2U1_HUMAN, Q7Z449
Function: Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May
modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes

Gene Wiki entry for CYP2U1


Genomic Views
for CYP2U1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CYP2U1 gene promoter:
         AML1a   POU6F1 (c2)   AP-4   HNF-3beta   GATA-1   YY1   AREB6   POU2F1   HSF2   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CYP2U1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CYP2U1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYP2U1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q25   Ensembl cytogenetic band:  4q25   HGNC cytogenetic band: 4q25

CYP2U1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CYP2U1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P108852:  view genomic region     (about GC identifiers)

Start:
 108,852,525 bp from pter      End:
 108,874,613 bp from pter
Size:
 22,089 bases      Orientation:
 plus strand

Proteins
for CYP2U1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CP2U1_HUMAN, Q7Z449 (See protein sequence)
Recommended Name: Cytochrome P450 2U1  
Size: 544 amino acids; 61987 Da
Cofactor: Heme group (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane
Developmental stage: Expressed in fetal thymus
Secondary accessions: B2RMV7 Q96EQ6
Alternative splicing: 2 isoforms:  Q7Z449-1   Q7Z449-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CYP2U1: NX_Q7Z449

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q7Z449

    • 4 DME Specific Peptides for CYP2U1 (Q7Z449)
     VSNIICS  EEIERVIG  NPQDFIDMYLLH  RAPSLTDKAQMPYTEATIMEVQRL 

    CYP2U1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_898898.1  
    ENSEMBL proteins: 
     ENSP00000333212   ENSP00000423667  
    Reactome Protein details: Q7Z449
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    Uscn Proteins for CYP2U1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0005792microsome ----
    GO:0016021integral to membrane IEA--


    CYP2U1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for CYP2U1

    Protein Domains /
    Families
    for CYP2U1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CYP2U1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR001128 Cyt_P450
     IPR017972 Cyt_P450_CS
     IPR002401 Cyt_P450_E_grp-I
     IPR008069 Cyt_P450_E_grp-I_CYP2D-like

    Graphical View of Domain Structure for InterPro Entry Q7Z449

    ProtoNet protein and cluster: Q7Z449

    1 Blocks protein family: IPB008069 CYP2D P450 family signature

    UniProtKB/Swiss-Prot: CP2U1_HUMAN, Q7Z449
    Similarity: Belongs to the cytochrome P450 family


    Function
    for CYP2U1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CP2U1_HUMAN, Q7Z449
    Function: Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May
    modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes
    Catalytic activity: RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O
    Biophysicochemical properties: Kinetic parameters: KM=2.7 uM for arachidonic acid;

    Enzyme Number (IUBMB): EC 1.14.14.11 2

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    hsa-miR-596 hsa-miR-607 hsa-miR-3135 hsa-miR-301a hsa-miR-1827 hsa-miR-4293 hsa-miR-130b hsa-miR-301b
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    In Situ Assay
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005506iron ion binding IEA--
    GO:0009055electron carrier activity IEA--
    GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen ----
    GO:0020037heme binding IEA--
    GO:0070330aromatase activity IEA--


    CYP2U1 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for CYP2U1:
     Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r 


    Pathways & Interactions
    for CYP2U1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cytochrome P450 - arranged by substrate type
    		Cytochrome P450 - arranged by substrate type1.00
    		cytochrome P4500.73
    		Phase 1 - Functionalization of compounds0.74
    2Metabolism
    		Metabolism1.00
    		Metabolism of lipids and lipoproteins0.34
    		Metabolic pathways0.38
    3Biological oxidations
    		Biological oxidations1.00
    		metapathway biotransformation0.41
    4superpathway of melatonin degradation
    		superpathway of melatonin degradation1.00
    		melatonin degradation I0.85
    5nicotine degradation III
    		nicotine degradation III1.00
    		nicotine degradation IV0.62

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/8 BioSystems Pathways for CYP2U1 (see all 8) 
        cytochrome P450
    acetone degradation I (to methylglyoxal)
    nicotine degradation IV
    bupropion degradation
    melatonin degradation I

    5/8        Reactome Pathways for CYP2U1 (see all 8)
        Cytochrome P450 - arranged by substrate type
    Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
    Miscellaneous substrates
    Metabolism
    Phase 1 - Functionalization of compounds


    2         Kegg Pathways  (Kegg details for CYP2U1):
        Arachidonic acid metabolism
    Metabolic pathways


    CYP2U1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CYP2U1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/47 Interacting proteins for CYP2U1 (Q7Z4493 ENSP000003332124) via UniProtKB, MINT, STRING, and/or I2D (see all 47)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    AOX1ENSP000003638324STRING: ENSP00000363832
    CYP2B6ENSP000003246484STRING: ENSP00000324648
    CYP2C18ENSP000002859794STRING: ENSP00000285979
    CYP2C19ENSP000003603724STRING: ENSP00000360372
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006805xenobiotic metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--


    CYP2U1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CYP2U1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for CYP2U1

    10 HMDB Compounds for CYP2U1    About this table
    CompoundSynonyms CAS #PubMed Ids
    10-HETE10-hydroxyeicosa-all-cis-5,8,11,14-tetraenoate (see all 2)167697-52-1--
    11beta-Hydroxytestosterone11beta,17beta-dihydroxyandrost-4-en-3-one 1816-85-9--
    13-HETE13-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoate (see all 2)151910-72-4--
    17-HETE17-hydroxyeicosatetraenate (see all 3)----
    2beta-Hydroxytestosterone2beta,17beta-dihydroxyandrost-4-en-3-one 10390-14-4--
    5-Oxo-6-trans-leukotriene B45-oxo-6E-LTB(,4) (see all 3)----
    6,7-dihydro-12-epi-LTB46,7-dihydro-12-epi-leukotriene B(,4) (see all 4)----
    6,7-dihydro-5-oxo-12-epi-LTB46,7-dihydro-5-oxo-12-epi-leukotriene B(,4) (see all 4)----
    Docosahexaenoic acid4,7,10,13,16,19-Docosahexaenoate (see all 14)6217-54-5--
    Heme(protoporphyrinato)iron (see all 19)14875-96-8--
    Search CenterWatch for drugs/clinical trials and news about CYP2U1 / CP2U1 

    Transcripts
    for CYP2U1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CYP2U1 gene: 
    NM_183075.2  

    Unigene Cluster for CYP2U1:

    Cytochrome P450, family 2, subfamily U, polypeptide 1
    Hs.109087  [show with all ESTs]
    Unigene Representative Sequence: NM_183075
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000332884(uc003hyp.3 uc011cfi.2) ENST00000513302 ENST00000508453


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    hsa-miR-596 hsa-miR-607 hsa-miR-3135 hsa-miR-301a hsa-miR-1827 hsa-miR-4293 hsa-miR-130b hsa-miR-301b
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    Inhib. RNA
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    Additional cDNA sequence: 

    AK026498.1 AK290002.1 AK298989.1 AK303284.1 AK304724.1 AY343323.1 BC012027.1 BC132767.1 
    BC136483.1 BC144148.1 

    2 DOTS entries:

    DT.101978979  DT.91796282 

    24/106 AceView cDNA sequences (see all 106):

    AA418010 N94925 N33755 BQ018912 BX426199 AW183742 AW264067 AA868720 
    BI966186 BM932043 AW027423 AI952800 AA099864 AA768918 BX426022 AA730070 
    AW889126 BU838483 BQ017879 CD672608 F09804 AL691830 AA905360 BG654708 

    GeneLoc Exon Structure


    Expression
    for CYP2U1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CYP2U1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTTTATTTGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See CYP2U1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CYP2U1

    SOURCE GeneReport for Unigene cluster: Hs.109087

    UniProtKB/Swiss-Prot: CP2U1_HUMAN, Q7Z449
    Tissue specificity: Widely expressed with stronger expression in thymus, heart and cerebellum

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    In Situ
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    Orthologs
    for CYP2U1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CYP2U1 gene from 6/17 species (see all 17)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves LOC4225281 cytochrome P450 2U1-like 68.3(n)
    66.6(a)    		   422528  XM_420491.3  XP_420491.3 
    zebrafish
    (Danio rerio)    		 Actinopterygii cyp2u11 cytochrome P450, family 2, subfamily U, polypeptide more 59.31(n)
    58.4(a)    		   556280  NM_001145564.1  NP_001139036.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Cyp18a11 Cytochrome P450-18a1 46.92(n)
    37.39(a)    		   32858  NM_078679.2  NP_523403.2 
    worm
    (Caenorhabditis elegans)    		 Secernentea cyp-33E26
    cyp-33E16
    (see all 25)    		 CYtochrome P450 family member (cyp-33E1)
    (see all 25)    		 30(a)
    30(a)
    (see all 25)    		 many ↔ many
    many ↔ many
    (see all 25)    		 IV(8612379-8614634)
    IV(8645518-8648168)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons CYP98A31 cytochrome P450 98A3 43.8(n)
    31.64(a)    		   818686  NM_180006.2  NP_850337.1 
    rice
    (Oryza sativa)    		 Liliopsida Os05g04940001 hypothetical protein 45.6(n)
    32.05(a)    		   4339188  NM_001062457.1  NP_001055922.1 


    ENSEMBL Gene Tree for CYP2U1 (if available)
    TreeFam Gene Tree for CYP2U1 (if available) 

    Paralogs
    for CYP2U1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CYP2U1 gene
    CYP2W12  CYP2C82  CYP2F12  CYP2A72  CYP2R12  CYP2J22  CYP2E12  CYP2D62  
    CYP2B7P12  CYP2A62  CYP2B62  CYP2C192  CYP2S12  CYP2C92  CYP2C182  CYP2A132  
    18/32 SIMAP similar genes for CYP2U1 using alignment to 2 protein entries:     CP2U1_HUMAN (see all proteins) (see all similar genes):
    CYP2G1P    CYP2R1    DKFZp686I24235    CYP2C9    CYP2J2    CYP2D7P1
    CYP2S1    CYP2A7    CYP2B6    CYP2D6    CYP2A13    CYP2A6
    CYP2B    CYP2B7    CYP 2C    CYP2A6V2    CYP2C19    CYP2E1

    CYP2U1 for paralogs           About GeneDecksing



    Genomic Variants
    for CYP2U1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYP2U1
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    Disorders / Diseases
    for CYP2U1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CYP2U1 for disorders           About GeneDecksing

    OMIM gene information: 610670    OMIM disorders: --

    4 diseases for CYP2U1:    About MalaCards
    alcohol dependence    cholesterol    alcoholism    retinitis

    Human Genome Epidemiology (HuGE) Navigator: CYP2U1 (2 documents)

    Export disorders for CYP2U1 gene to outside databases

    Publications
    for CYP2U1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CYP2U1 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with CYP2U1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids. (PubMed id 14660610)1, 2, 3, 9 Chuang S.S.... Korczak B. (2004)
    2. Characterization and tissue distribution of a novel human cytochrome P450-CYP2U1. (PubMed id 14975754)1, 2, 3 Karlgren M....Ingelman-Sundberg M. (2004)
    3. Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain mic rovessels. (PubMed id 21707071)1 Shawahna R....Scherrmann J.M. (2011)
    4. A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1 Kalsi G....Riley B.P. (2010)
    5. Genetic polymorphism of CYP2U1, a cytochrome P450 inv olved in fatty acids hydroxylation. (PubMed id 20630735)1 Devos A....Cauffiez C. (2010)
    6. Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues. (PubMed id 15752708)2 Choudhary D.... Schenkman J.B. (2005)
    7. 'Frankenstein genes', or the Mad Magazine version of the human pseudogenome. (PubMed id 15588491)1 Nelson D.R. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. (PubMed id 15128046)1 Nelson D.R....Nebert D.W. (2004)
    10. Expressed sequence tag analysis of adult human iris for the NEIBank project: steroid-response factors and similarities with retinal pigment epithelium. (PubMed id 12107412)1 Wistow G.... Peterson K. (2002)

    External Searches for CYP2U1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing CYP2U1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 113612 HGNC: 20582 AceView: CYP2U1 Ensembl:ENSG00000155016 euGenes: HUgn113612
    ECgene: CYP2U1 Kegg: 113612 H-InvDB: CYP2U1

    Other Databases showing CYP2U1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CYP2U1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CYP2U1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CYP2U1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CYP2U1 gene:
    Search GeneIP for patents involving CYP2U1

    GeneCards and IP:
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