CYP2A7 Gene
protein-coding GIFtS: 57
GCID: GC19M041381
|
|
cytochrome P450, family 2, subfamily A, polypeptide 7(Previous names: cytochrome P450, subfamily IIA (phenobarbital-inducible),...)
| |
Aliases
for CYP2A7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cytochrome P450, Family 2, Subfamily A, Polypeptide 71 2 | | CPA72 | | CYP2A1 2 | | CPAD2 | | Cytochrome P450, Subfamily IIA (Phenobarbital-Inducible), Polypeptide 71 2 | | P450-IIA42 | | Cytochrome P450 IIA42 3 | | Cytochrome P450 2A72 | | CYPIIA72 3 | | Cytochrome P450IIA42 | | EC 1.14.14.13 8 | | |
Export aliases for CYP2A7 gene to outside databasesPrevious GC identifers: GC19M042020 GC19M041773 GC19M046002 GC19M046018 GC19M046020 GC19M046073 GC19M041350 |
Summaries
for CYP2A7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CYP2A7:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids andother lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. Thisgene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A,CYP2B and CYP2F subfamilies on chromosome 19q. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CP2A7_HUMAN, P20853Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved inan NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, includingsteroids, fatty acids, and xenobiotics
Gene Wiki entry for CYP2A7
|
Genomic Views
for CYP2A7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CYP2A7 gene promoter:
USF1 SREBP-1a USF-1 GCNF GCNF-1 IRF-7A STAT3 GCNF-2 SREBP-1b
Other transcription factors
Search SABiosciences Chromatin IP Primers for CYP2A7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYP2A7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.2 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.2CYP2A7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M041381: view genomic region
(about GC identifiers)
Start:
|
41,381,344 bp from pter |
End:
|
41,388,657 bp from pter |
Size:
|
7,314 bases |
Orientation:
|
minus strand |
|
Proteins
for CYP2A7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CP2A7_HUMAN, P20853 (See
protein sequence)Recommended Name: Cytochrome P450 2A7 Size: 494 amino acids; 56425 Da
Cofactor: Heme group (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheralmembrane protein
Secondary accessions: Q13121Explore the universe of human proteins at neXtProt for CYP2A7: NX_P20853
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P20853
4/21 DME Specific Peptides for CYP2A7 (P20853) (see all 21)
CYP2A7 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins (2 alternative transcripts):
NP_000755.2 NP_085079.2
ENSEMBL proteins: ENSP00000301146 ENSP00000291764 Reactome Protein details: P20853
Human Recombinant Protein Products for CYP2A7:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005789 | endoplasmic reticulum membrane |
IEA | -- | | GO:0005792 | microsome |
-- | -- |
CYP2A7 for ontologies About GeneDecksing
CYP2A7 Antibody Products:
Assay Products for CYP2A7: |
Protein
Domains /
Families
for CYP2A7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CYP2A7 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P20853ProtoNet protein and cluster: P20853 2 Blocks protein families: IPB002401 E-class P450 group I signature IPB008067 CYP2A P450 family signature
UniProtKB/Swiss-Prot: CP2A7_HUMAN, P20853Similarity: Belongs to the cytochrome P450 family |
Function
for CYP2A7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CP2A7_HUMAN, P20853Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved inan NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, includingsteroids, fatty acids, and xenobioticsCatalytic activity: RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)OInduction: P450 can be induced to high levels in liver and other tissues by various foreign compounds, including drugs,pesticides, and carcinogens Genatlas biochemistry entry for CYP2A7:cytochrome P450,subfamily IIA (phenobarbital-inducible),polypeptide 7
Enzyme Number (IUBMB): EC 1.14.14.11 2
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004497 | monooxygenase activity |
-- | -- | | GO:0005506 | iron ion binding |
IEA | -- | | GO:0009055 | electron carrier activity |
IEA | -- | | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
-- | -- | | GO:0019825 | oxygen binding |
TAS | 7864805 |
CYP2A7 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for CYP2A7:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2A7 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2A7 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CYP2A7 (NM_030589) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CYP2A7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP2A7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP2A7 |
|
Pathways & Interactions
for CYP2A7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cytochrome P450 - arranged by substrate type | | | 2 | Xenobiotics | | | 3 | Metabolism | | | 4 | Drug metabolism - cytochrome P450 | | | 5 | Biological oxidations | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for CYP2A7
5/6 
Reactome Pathways for CYP2A7 (see all 6)
5 
Kegg Pathways (Kegg details for CYP2A7):
CYP2A7 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CYP2A7
|
Drugs & Compounds
for CYP2A7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CYP2A7 for compounds About GeneDecksing
 Browse Tocris compounds for CYP2A7
10/49 HMDB Compounds for CYP2A7 (see all 49) About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| 10-HETE | 10-hydroxyeicosa-all-cis-5,8,11,14-tetraenoate (see all 2) | 167697-52-1 | -- | | 11,12,15-THETA | 11,12,15-Trihydroxyicosatrienoic acid (see all 5) | -- | -- | | 11,12-Epoxyeicosatrienoic acid | 10-(3-(2-octenyl)oxiranyl)-5,8-Decadienoic acid (see all 15) | 81276-02-0 | -- | | 11,14,15-THETA | (5Z,8Z,12E)-11,14,15-Trihydroxyeicosa-5,8,12-trienoic acid (see all 8) | -- | -- | | 11H-14,15-EETA | 14,15-Ep-11-HETrE (see all 11) | 219535-29-2 | -- | | 11beta-Hydroxytestosterone | 11beta,17beta-dihydroxyandrost-4-en-3-one | 1816-85-9 | -- | | 12,13-EpOME | Vernolic acid (see all 12) | -- | -- | | 13-HETE | 13-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoate (see all 2) | 151910-72-4 | -- | | 14,15-Epoxy-5,8,11-eicosatrienoic acid | (5Z,8Z,11Z)-14,15-Epoxyicosa-5.8.11-trienoic acid (see all 11) | 81276-03-1 | -- | | 15(S)-HPETE | (5Z,8Z,11Z,13E)-(15S)-15-Hydroperoxyicosa-5,8,11,13-tetraenoate (see all 8) | 70981-96-3 | -- |
2 Novoseek chemical compound relationships for CYP2A7 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| coumarin |
74.4 |
1 |
11016631 (1) |
| nicotine |
61.7 |
1 |
11016631 (1) |
Search CenterWatch for drugs/clinical trials and news about CYP2A7 / CP2A7
|
Transcripts
for CYP2A7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CYP2A7 gene (2 alternative transcripts): NM_000764.2 NM_030589.2 Unigene Cluster for CYP2A7: Cytochrome P450, family 2, subfamily A, polypeptide 7 Hs.719890 [show with all ESTs]Unigene Representative Sequence: U220292 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000301146(uc002opm.3 uc002opo.3) ENST00000291764(uc002opn.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2A7 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2A7 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CYP2A7 (NM_030589) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CYP2A7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP2A7 |
Additional cDNA sequence: BC117165.1 BC143325.1 K03192.1 M33317.1 U22029.1 9 DOTS entries: DT.102836902 DT.441444 DT.102820753 DT.100796642 DT.92430530 DT.121503458 DT.100796640 DT.95161335 DT.92430534 24/114 AceView cDNA sequences (see all 114): NM_030589 NM_000764 NM_000762 AV661332 X13929 M33317 CB137781 CB142718 CB121445 BM979947 CB135601 AV646570 CB137671 CB124837 CB146612 CB146694 CB147167 BQ302898 CB130051 CB116943 BV207402 X13897 CB121427 CB138212
GeneLoc Exon Structure
|
Expression
for CYP2A7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CYP2A7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for CYP2A7
SOURCE GeneReport for Unigene cluster: Hs.719890
SABiosciences Custom PCR Arrays for CYP2A7
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYP2A7
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat CYP2A7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYP2A7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYP2A7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP2A7 |
Orthologs
for CYP2A7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CYP2A7 gene from 3/8 species (see all 8) About this table
ENSEMBL Gene Tree for CYP2A7 (if available)
TreeFam Gene Tree for CYP2A7 (if available) |
Paralogs
for CYP2A7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CYP2A7 gene
- CYP2W12 CYP2C82 CYP2F12 CYP2R12 CYP2J22 CYP2U12 CYP2E12 CYP2D62
- CYP2B7P12 CYP2A62 CYP2B62 CYP2C192 CYP2S12 CYP2C92 CYP2A132 CYP2C182
18/29 SIMAP similar genes for CYP2A7 using alignment to 5 protein entries: CP2A7_HUMAN (see all proteins)
(see all similar genes):CYP2A6 CYP2A6V2 CYP2A13 CYP2G1P CYP2C CYP2B
CYP2B7 CYP2C9 CYP2C8 CYP 2C CYP2C19 CYP2S1
CYP2F1 CYP2E1 CYP2C18 CYP2B6 CYP2J2 CYP2R1
CYP2A7 for paralogs About GeneDecksing
|
Genomic Variants
for CYP2A7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CYP2A7 (41381344 - 41388657 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for CYP2A7
8 CNVs: 32255 4081 89238 7205 23223 78193 67546 89235 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYP2A7 |
|
Disorders
/ Diseases
for CYP2A7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CYP2A7 for disorders About GeneDecksing
OMIM gene information: 608054
OMIM disorders: --
1  disease for CYP2A7: About MalaCardscholesterol
Genetic Association Database (GAD): CYP2A7
Human Genome Epidemiology (HuGE) Navigator: CYP2A7 (8 documents)
Export disorders for CYP2A7 gene to outside databases
|
Publications
for CYP2A7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CYP2A7 gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with CYP2A7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. (PubMed id 7668294)1, 2, 3, 9 Fernandez-Salguero P.... Idle J.R. (1995)
- Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity. (PubMed id 12325023)1, 4, 9 Oscarson M....Ingelman-Sundberg M. (2002)
- Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. (PubMed id 15128046)1, 3 Nelson D.R....Nebert D.W. (2004)
- The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes. (PubMed id 2322567)1, 2 Yamano S.... Gonzalez F.J. (1990)
- Expression and alternative splicing of the cytochrome P-450 CYP2A7. (PubMed id 7864805)1, 9 Ding S....Wolf C.R. (1995)
- Expression of CYP2A genes in human liver and extrahepatic tissues. (PubMed id 10353262)1, 9 Koskela S....Raunio H. (1999)
- Differential distribution of CYP2A6 and CYP2A13 in the human respiratory tract. (PubMed id 22890016)1 Chiang H.C....Tsou T.C. (2012)
- CYP2A7 polymorphic alleles confound the genotyping of CYP2A6*4A allele. (PubMed id 16636685)1 Fukami T....Yokoi T. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism. (PubMed id 11960914)1 Godoy W....Pinto L.F. (2002)
|
External Searches for CYP2A7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CYP2A7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CYP2A7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CYP2A7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CYP2A7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CYP2A7 gene:
Search GeneIP for patents involving CYP2A7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CYP2A7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CYP2A7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CYP2A7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYP2A7 | | | OriGene Protein Over-expression Lysate for CYP2A7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CYP2A7 | | OriGene 3'-UTR Clone for CYP2A7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2A7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYP2A7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CYP2A7 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CYP2A7 | | OriGene Custom Protein Services for CYP2A7 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CYP2A7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYP2A7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYP2A7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CYP2A7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYP2A7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYP2A7 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CYP2A7 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | CYP2A7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP2A7 |
|  |  |  |  | | | | ThermoFisher Antibody for CYP2A7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP2A7 |
| |  | |
|
|
|
