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CYP2A13 Gene

protein-coding   GIFtS: 59

GC19P041594
cytochrome P450, family 2, subfamily A, polypeptide 13
(Previous names: cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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Aliases &
Descriptions
for CYP2A13 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases & Descriptions
cytochrome P450, family 2, subfamily A, polypeptide 131 2     CYPIIA132 3
CPAD1 2     cytochrome P450 2A132
CYP2A1 2     EC 1.14.14.13
cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 131 2     

External Ids:    HGNC: 26081   Entrez Gene: 15532   Ensembl: ENSG000001978387   UniProtKB: Q166963   

Search outside databases for aliases for CYP2A13 gene

Previous GC identifers: GC19P042233 GC19P041986 GC19P046108 GC19P046126 GC19P046130 GC19P046286

Summaries
for CYP2A13 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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  User Feedback		 Entrez Gene summary for CYP2A13:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and
other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been
determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to
tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on
chromosome 19q. (provided by RefSeq)

UniProtKB/Swiss-Prot: CP2AD_HUMAN, Q16696
Function: Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide,
N,N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen,
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity

Gene Wiki entry for CYP2A13

Genomic Views
for CYP2A13 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences)
About This Section

  User Feedback		 Regulatory elements:
"" SABiosciences Regulatory transcription factor binding sites in the CYP2A13 gene upstream (promoter) region "":
C/EBPalpha   NRSF form 1   NRSF form 2   Max1   c-Myc   NF-1   ISGF-3   FOXI1   POU2F1   GR-alpha   

Epigenetics:
"" SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for CYP2A13:  ""
MePH24661-1A   

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.2

CYP2A13 Gene in genomic location: bands according to Ensembl, locations according to "" (and/or Entrez Gene and/or Ensembl if different)
""

GeneLoc gene densities for chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P041594:  view genomic region     (about GC identifiers)

Start:
 41,594,368 bp from pter
End:
 41,602,099 bp from pter
Size:
 7,732 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  

Proteins
for CYP2A13 gene

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
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  User Feedback		 UniProtKB/Swiss-Prot: CP2AD_HUMAN, Q16696 (See protein sequence)
Recommended Name: Cytochrome P450 2A13  
Size: 494 amino acids; 56688 Da
Cofactor: Heme group
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral
membrane protein
PDB structures from "" and Proteopedia "" :
2P85 (3D) ""    2PG5 (3D) ""    2PG6 (3D) ""    2PG7 (3D) ""    
Secondary accessions: Q53YR8 Q6R569 Q6R570 Q9H2X2

REFSEQ proteins: NP_000757.2  

ENSEMBL proteins: 
ENSP00000332679 ENSP00000413250 


Human Recombinant Proteins 
""Browse Purified and Recombinant Proteins at Millipore
""Sigma-Aldrich AQUA Peptides for CYP2A13
"" Browse R&D Systems for human recombinant proteins
""Enzo Life Sciences proteins for CYP2A13
""HuPro® and/or Recombinant Proteins from Abnova for CYP2A13 ""
""Browse Origene full length recombinant human proteins expressed in human HEK293 cells
""Novus Biologicals Proteins for CYP2A13  ""
""Browse Sino Biological Recombinant Proteins  ""

5 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005783 endoplasmic reticulum IEA--
GO:0005789 endoplasmic reticulum membrane EXP15196988
GO:0005792 microsome IEA--
GO:0016020 membrane IEA--
GO:0019898 extrinsic to membrane ----
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Antibodies for CYP2A13: 
""Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
""Sigma-Aldrich Antibodies for CYP2A13
"" Browse R&D Systems for Antibodies
""Monoclonal and Polyclonal Antibodies from Abnova (CYP2A13)
""Browse Origene Antibodies ""
""Novus Biologicals Antibodies for CYP2A13
""Browse antibodies at Epitomics

Assays for CYP2A13: 
""Browse Kits and Assays available from Millipore
""Browse ELISAs at Sigma-Aldrich
"" Browse R&D Systems for biochemical assays
""Enzo Life Sciences assays for CYP2A13

Protein Domains/
Families
for CYP2A13 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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5 InterPro domains/families:
 IPR001128 Cyt_P450
 IPR017973 Cyt_P450_C
 IPR017972 Cyt_P450_CS
 IPR002401 Cyt_P450_E_grp-I
 IPR008067 Cyt_P450_E_grp-I_CYP2A-like

Graphical View of Domain Structure for InterPro Entry Q16696

ProtoNet protein and cluster: Q16696

2 Blocks protein families:
IPB002401 E-class P450 group I signature
IPB008067 CYP2A P450 family signature


UniProtKB/Swiss-Prot: CP2AD_HUMAN, Q16696
Similarity: Belongs to the cytochrome P450 family

Gene Function
for CYP2A13 gene

(According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
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Inhib.
RNA:		""Browse for Gene Knock-down Tools from Millipore
""Abnova Chimera RNAi Products for Gene knock-down (CYP2A13)
"" Origene 29mer shRNA kits in GFP-retroviral vector: CYP2A13
Origene shRNA RFP: CYP2A13
Origene basic RS shRNA: CYP2A13

""Applied Biosystems Silencer® siRNAs for CYP2A13
""Sigma-Aldrich siRNA Panels and siRNA for CYP2A13
Sigma-Aldrich shRNA for CYP2A13
Explore Sigma-Aldrich super-pooled esiRNAs
Clones:""Browse Clones for the Expression of Recombinant Proteins Available from Millipore
""Browse iPSC Reprogramming Factors at Sigma-Aldrich
"" Origene GFP tagged cDNA clones in CMV expression vector: CYP2A13
Origene Myc/DDK tagged cDNA clones in CMV expression vector: CYP2A13
Origene untagged cDNA clones in CMV expression vector: CYP2A13
""Browse Sino Biological Human cDNA Clones  ""

UniProtKB/Swiss-Prot: CP2AD_HUMAN, Q16696
Function: Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide,
N,N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen,
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity
Catalytic activity: RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O
Biophysicochemical properties: Kinetic parameters: KM=10.7 uM for phenacetin;
Enzyme Number (IUBMB): EC 1.14.14.1 

Genatlas biochemistry entry for CYP2A13:
cytochrome P450,subfamily IIA (phenobarbital-inducible),polypeptide 13

5/7 Gene Ontology (GO) molecular function terms (GO ID links to tree view) (see all 7 ):

GO IDQualified GO termEvidencePubMed IDs
GO:0004497 monooxygenase activity ----
GO:0005506 iron ion binding ----
GO:0008389 coumarin 7-hydroxylase activity EXP15196988
GO:0009055 electron carrier activity IEA--
GO:0020037 heme binding IDA17428784
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Pathways & Interactions
for CYP2A13 gene

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
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"" CYP2A13 for pathways           About GeneDecksing

2 "" Millipore Pathways for CYP2A13
  ""  Androstenedione and testosterone biosynthesis and metabolism p.1
Acetaminophen metabolism

5/6 "" Sigma-Aldrich "Your Favorite Gene" Pathways for  CYP2A13  (Your Favorite Gene powered by Ingenuity) (see all 6 )
  ""  Linoleic Acid Metabolism
Metabolism of Xenobiotics by Cytochrome P450
LPS/IL-1 Mediated Inhibition of RXR Function
Arachidonic Acid Metabolism
Fatty Acid Metabolism

5 "" Kegg Pathways  (Kegg details for CYP2A13):
  ""  hsa00232 Caffeine metabolism
hsa00830 Retinol metabolism
hsa00982 Drug metabolism - cytochrome P450
hsa00983 Drug metabolism - other enzymes
hsa01100 Metabolic pathways

"" Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CYP2A13

4 Interacting proteins for CYP2A13 (ENSP000003326793) via UniProtKB, MINT, and/or STRING ""
InteractantInteraction Details
GeneCardExternal ID(s)
NAT2ENSP000002864793STRING: ENSP00000286479
CYP1A2ENSP000003420073STRING: ENSP00000342007
CYP2A6ENSP000003011413STRING: ENSP00000301141
--ENSP000003501333STRING: ENSP00000350133
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1 Gene Ontology (GO) biological process term (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0055114 oxidation reduction IEA--
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Drugs & Compounds
for CYP2A13 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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"" Enzo Life Sciences drugs & compounds for CYP2A13
""Browse Small Molecules at Sigma-Aldrich

"" Browse Tocris compounds for CYP2A13
10/35 ""Novoseek chemical compound relationships for CYP2A13 gene (see all 35 )
Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone 50.38 18 17717079 (2), 17671098 (2), 19608696 (1), 18423367 (1) (see all 16)
coumarin 23.46 13 15196988 (4), 19251817 (3), 17922361 (2), 19074523 (1) (see all 7)
2-methoxyacetophenone 16.56 4 19251817 (3), 11016631 (1)
aflatoxin b1 15.58 11 16385575 (5), 16917071 (2), 16815959 (2), 18779312 (1) (see all 5)
phenacetin 13.75 7 18779312 (4), 17178771 (3)
8 methoxypsoralen 11.65 7 15958517 (3), 18813816 (2), 17671098 (1), 15579482 (1)
3-methylindole 10.30 5 19608696 (4), 20187624 (1)
nicotine 10.00 13 16188955 (5), 15528319 (5), 19434638 (1), 18779312 (1) (see all 5)
75-20 c 8.78 2 15175424 (2)
cotinine 8.75 6 15528319 (4), 18779312 (1), 16188955 (1)
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Transcripts
for CYP2A13 gene

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
Expression Assays from Applied Biosystems)
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Inhib.
RNA:		""Browse for Gene Knock-down Tools from Millipore
""Abnova Chimera RNAi Products for Gene knock-down (CYP2A13)
""Applied Biosystems Silencer® siRNAs:  NM_000766  
"" Origene 29mer shRNA kits in GFP-retroviral vector: CYP2A13
Origene shRNA RFP: CYP2A13
Origene basic RS shRNA: CYP2A13

""Sigma-Aldrich siRNA Panels and siRNA for CYP2A13
Sigma-Aldrich shRNA for CYP2A13
Explore Sigma-Aldrich super-pooled esiRNAs

microRNA:""Search SABiosciences for microRNAs that regulate CYP2A13: ""
Assays:  ""Applied Biosystems TaqMan® Gene Expression Assays:  
NM_000766  


Clones:"" Origene GFP tagged cDNA clones in CMV expression vector: CYP2A13
Origene Myc/DDK tagged cDNA clones in CMV expression vector: CYP2A13
Origene untagged cDNA clones in CMV expression vector: CYP2A13
Primers:"" Origene genome-wide validated SYBR primer pairs: CYP2A13
""SABiosciences RT2 qPCR Primer Assay for CYP2A13: PPH13808A ""

REFSEQ mRNAs for CYP2A13 gene: 

NM_000766.3  

Additional cDNA sequence: 

AF209774.1 AY513604.1 AY513605.1 AY513606.1 AY513607.1 AY513608.1 AY513609.1 

2 DOTS entries:

DT.102820753  DT.121503364 

11 AceView cDNA sequences:

AY513606 NM_000766 AY513605 AY513604 AF209774 AY513607 AY513608 AY513609 
BM975825 CD609500 CD609501 

"" highest scoring ESTs for CYP2A13:

AF209774 AY513604 AY513605 AY513606 AY513607 AY513608 AY513609 BM975825 NM_000766 AV698396 

Unigene Cluster for CYP2A13:

Cytochrome P450, family 2, subfamily A, polypeptide 13
Hs.567252
Unigene Representative Sequence: NM_000766


GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:
ENST00000330436  ENST00000430558  

Expression
for CYP2A13 gene

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
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CYP2A13 expression in normal and diseased human tissues

"" Applied Biosystems TaqMan ® Gene Expression Assays for CYP2A13

1""  / 2""  / 3""

5 probe-sets matching CYP2A13 gene

Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
1552_i_at2, 3 U95-A 1 0.50 1.00 0.50 1.46 U22028 0.20 1.00 0.72 1
1554_f_at2, 3 U95-A 3 0.50 0.61 0.80 0.84 U22028 0.20 1.00 0.72 1
1553_r_at2, 3 U95-A 1 0.36 1.00 0.74 0.84 U22028 0.20 1.00 0.72 1
208327_at2, 3 U133-A 2 0.55 0.92 -- -- NM_000766 0.60 1.00 0.82 1
208327_at2 U133Plus2 2 0.55 0.92 -- -- -- -- -- -- --
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Data from Genenote  (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.567252

Expression variation in blood from EXPOLDB for CYP2A13

UniProtKB/Swiss-Prot: CP2AD_HUMAN, Q16696
Tissue specificity: Expressed in liver and a number of extrahepatic tissues, including nasal mucosa, lung, trachea,
brain, mammary gland, prostate, testis, and uterus, but not in heart, kidney, bone marrow, colon, small intestine,
spleen, stomach, thymus, or skeletal muscle

Primers:"" Origene genome-wide validated SYBR primer pairs: CYP2A13 ""
""SABiosciences RT2 qPCR Primer Assay for CYP2A13: PPH13808A ""

Orthologs
for CYP2A13 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for CYP2A13 gene from 5/8 species (see all 8 )
Organism Gene Locus Description Human
Similarity		 NCBI accessions
chimpanzee
(Pan troglodytes)		 LOC7388231   -- similar to cytochrome P450 2A13 variant 5 83.14(n)
81.61(a)		 738823  XM_001139878.1  XP_001139878.1 
rat
(Rattus norvegicus)		 Cyp2a3a1   -- cytochrome P450, family 2, subfamily A, polypeptide more 85.63(n)
88.87(a)		 24299  NM_012542.1  NP_036674.1 
mouse
(Mus musculus)		 Cyp2a51   -- cytochrome P450, family 2, subfamily a, polypeptide more 85.49(n)
88.46(a)		 13087  NM_007812.3  NP_031838.2 
zebrafish
(Danio rerio)		 zgc558562   -- hypothetical protein MGC55856 73.45(n) 393204  BC046898.1 
fruit fly
(Drosophila melanogaster)		 Cyp303a13 35F5 cytochrome P450 28(a)
(best of 2)		   --
About this table        Species with no ortholog for CYP2A13

ENSEMBL Gene Tree for CYP2A13

Paralogs
for CYP2A13 gene

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
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Paralogs for CYP2A13 gene
CYP2A61 2  CYP2A71  CYP2W12  CYP2C82  CYP2G1P2  CYP2F12  CYP2C192  CYP2B62  
CYP2R12  CYP2U12  CYP2J22  CYP2S12  CYP2E12  CYP2C92  CYP2D62  CYP2D7P12  
CYP2C182  

"" CYP2A13 for paralogs           About GeneDecksing


Genomic Variants
for CYP2A13 gene

(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
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  User Feedback		UniProtKB/Swiss-Prot: CP2AD_HUMAN, Q16696
Polymorphism: The frequencies of the Cys-257 allele in white, black, Hispanic, and Asian individuals are 1.9%, 14.4%,
5.8%, and 7.7%, respectively. The Cys-257 variant is 37 to 56% less active than the wild-type Arg-257 protein toward
all substrates tested


10/122 NCBI SNPs in CYP2A13 are shown (see all 122 )
(Click "" for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 34)
ABGenomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 19 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
------------
""
rs17090841,2
C,F,O,A38034582(+) GTGTAA/GTCTGA 1 -- ng31""108Minor allele frequency- N:0.00NS EA NA PA EU CA WA 7272""
--
rs3059871,2
C,O,A,H38026085(-) TTTTAT/CTAGGG 1 -- ng51 tfbs3""5Minor allele frequency- C:0.00NS EA NA 420""
--
rs3059891,2
C,A,H38025017(+) gatcaC/Tgatga 1 -- ng51""0--------
--
rs24537921,2
C,F,A38024545(-) GGGCTG/CTGACA 1 -- ng51""4Minor allele frequency- C:0.38NA 8""
--
rs24537911,2
C,A,H38024590(-) AGGGCG/ATAAGG 1 -- ng51""2Minor allele frequency- A:0.25NA 4""
--
rs17090831,2
C,A,H41601896(+) ACGGCG/CGGGGC 1 -- ut31 ese3""2Minor allele frequency- C:0.25NA 4""
--
rs3059881,2
C,A,H38025256(+) TGCCTG/ACTAAT 1 -- ng51""1Minor allele frequency- A:0.00NA 2""
--
rs26449141,2
F,O,A41358011(+) ATTGGC/TGGGTT 1 -- ng51""2Minor allele frequency- T:0.50NA 4""
--
rs81927891,2
C,F41597751(+) ACCAGC/TGCACG 2 R C ref1 mis1 ese3""10Minor allele frequency- T:0.25MN NA NS EA 902""
--
rs37452841,2
C,F41601947(+) GCAGTG/CGGGGA 1 -- ut31""1Minor allele frequency- C:0.06EA 1502""
About this table

HapMap Linkage Disequilibrium images for CYP2A13 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)  ""
      Database of Genomic Variants (DGV) variations for CYP2A13: --

Disorders & Mutations
for CYP2A13 gene

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 608055

10/14 ""Novoseek disease relationships for CYP2A13 gene (see all 14 )

Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
adenocarcinoma lung 9.30 6 14633739 (4), 18669584 (2)
lung adenoma 6.53 3 18813816 (2), 15958517 (1)
lung cancer 6.46 12 16815959 (3), 19414505 (2), 14633739 (2), 18669584 (1) (see all 8)
chemical carcinogenesis 3.46 2 7581481 (1), 17148654 (1)
pancreatic cancer 2.46 4 19812523 (4)
dystrophy; myotonic 2.23 2 1975560 (2)
nonsense mutation 1.16 1 12920161 (1)
lung tumor 0.86 1 15175424 (1)
adenocarcinoma 0.64 2 18813816 (2)
adenoma 0.34 1 15958517 (1)
About this table

Locus Specific Mutation Databases: CYP2A13
Human Gene Mutation Database: CYP2A13
Genetic Association Database: CYP2A13
Human Genome Epidemiology Navigator: CYP2A13 (15 documents)

Medical News
for CYP2A13 gene

(Possibly Related Articles in Doctor's Guide)
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Publications
for CYP2A13 gene

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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  User Feedback		15/60 PubMed articles for CYP2A13 gene (see all 60 ):

Search for CYP2A13 gene

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Disorders
Search String
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing CYP2A13 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 1553 HGNC: 2608 AceView: CYP2A13 Ensembl:ENSG00000197838 euGenes: HUgn1553
ECgene: CYP2A13 Kegg: 1553 H-InvDB: CYP2A13

Other Databases showing CYP2A13 gene

(According to HUGE)
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Specialized Databases showing CYP2A13 gene

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
Cytochrome P450 Allele Nomenclature Committeehttp://www.cypalleles.ki.se/cyp2a13.htm

Intellectual Property
for CYP2A13 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
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  User Feedback		Patent Information for CYP2A13 gene: ""
Search GeneIP for patents involving CYP2A13

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Services
for CYP2A13 gene

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Novus Biologicals,
Epitomics, Sigma-Aldrich, R&D Systems, SABiosciences, Millipore, Abnova,
Clones available from OriGene, Sigma-Aldrich, Sino Biological, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience)
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Products for CYP2A13:
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"" Recombinant & Natural Proteins  

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"" Search Tocris compounds for CYP2A13
"" Regulatory tfbs in CYP2A13 upstream (promoter) region
"" Search Chromatin IP Primers for CYP2A13
"" DNA Methylation qPCR Primer Assays for CYP2A13
"" RT2 qPCR Primer Assay for CYP2A13
"" Search GNC Networks for CYP2A13
"" Search for microRNAs that regulate CYP2A13
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"" Assays/Drugs/Proteins for CYP2A13
"" Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
"" Novus Tissue Slides
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"" Browse Sino Biological cDNA Clones
"" Antibodies/Proteins Production Services
"" Rabbit Monoclonal Antibody Platform
"" Bulk Purchasing
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GeneCards Homepage - Last full update: 20 May 2010 - Incremental updates: 24 May 2010 , 20 Jun 2010

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