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Aliases for CYP2A Gene

Aliases for CYP2A Gene

  • Cytochrome P450, Family 2, Subfamily A 2 3
  • Cytochrome P450, Subfamily IIA (Phenobarbital-Inducible) 2 3
  • P450C2A 3
  • P450C2 3
  • P450PB 3
  • CYP1 3
  • CYP2 3

External Ids for CYP2A Gene

Previous HGNC Symbols for CYP2A Gene

  • CYP1

Previous GeneCards Identifiers for CYP2A Gene

  • GC00U921689
  • GC19P041315

Summaries for CYP2A Gene

Entrez Gene Summary for CYP2A Gene

  • The cytochrome P450 superfamily of enzymes are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP2 gene cluster on chromosome 19q13.2 includes several genes and pseudogenes from the CYP2A, CYP2B, and CYP2F subfamilies. [provided by RefSeq, Jul 2008]

GeneCards Summary for CYP2A Gene

CYP2A (Cytochrome P450, Family 2, Subfamily A) is a Genetic Locus. Diseases associated with CYP2A include coumarin resistance and nicotine dependence, protection against.

Gene Wiki entry for CYP2A Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP2A Gene

Genomics for CYP2A Gene

Genomic Location for CYP2A Gene

Chromosome:
19
Orientation:
Unknown strand

Genomic View for CYP2A Gene

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for CYP2A Gene

No data available for Regulatory Elements for CYP2A Gene

Proteins for CYP2A Gene

Post-translational modifications for CYP2A Gene

No Post-translational modifications

No data available for DME Specific Peptides for CYP2A Gene

Domains & Families for CYP2A Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CYP2A Gene

Function for CYP2A Gene

Molecular function for CYP2A Gene

GENATLAS Biochemistry:
cytochrome P450,subfamily IIA (phenobarbital-inducible)

Phenotypes for CYP2A Gene

GenomeRNAi human phenotypes for CYP2A:
genes like me logo Genes that share phenotypes with CYP2A: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CYP2A Gene

Localization for CYP2A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CYP2A Gene

Pathways & Interactions for CYP2A Gene

SuperPathways for CYP2A Gene

No Data Available

Interacting Proteins for CYP2A Gene

Gene Ontology (GO) - Biological Process for CYP2A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CYP2A Gene

Drugs & Compounds for CYP2A Gene

(2) Drugs for CYP2A Gene - From: NovoSeek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phenobarbital Approved Pharma Agonist 33
Coumarin Experimental Nutra 14
genes like me logo Genes that share compounds with CYP2A: view

Transcripts for CYP2A Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CYP2A Gene

No ASD Table

Relevant External Links for CYP2A Gene

ECgene alternative splicing isoforms for
CYP2A

No data available for mRNA/cDNA for CYP2A Gene

Expression for CYP2A Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CYP2A Gene

Orthologs for CYP2A Gene

No data available for Orthologs and Evolution for CYP2A Gene

Paralogs for CYP2A Gene

No data available for Paralogs for CYP2A Gene

Variants for CYP2A Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for CYP2A Gene

Disorders for CYP2A Gene

MalaCards: The human disease database

(3) MalaCards diseases for CYP2A Gene - From: OMIM

Disorder Aliases PubMed IDs
coumarin resistance
  • warfarin sensitivity
nicotine dependence, protection against
  • nicotine dependence
lung cancer
  • lung cancer, protection against
- elite association
Search CYP2A in MalaCards View complete list of genes associated with diseases

Relevant External Links for CYP2A

Genetic Association Database (GAD)
CYP2A
Human Genome Epidemiology (HuGE) Navigator
CYP2A
genes like me logo Genes that share disorders with CYP2A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CYP2A Gene

Publications for CYP2A Gene

  1. Xenobiotic-metabolizing cytochromes p450 in human white adipose tissue: expression and induction. (PMID: 20035023) Ellero S. … de Waziers I. (Drug Metab. Dispos. 2010) 23 67
  2. [Clinical significance of some genetic polymorphisms of cytochrome P-450: family CYP1 and subfamilies CYP2A, CYP2B and CYP2C]. (PMID: 19388543) Wojtczak A. … Skretkowicz J. (Pol. Merkur. Lekarski 2009) 23 67
  3. Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease. (PMID: 19651758) Fisher C.D. … Cherrington N.J. (Drug Metab. Dispos. 2009) 23 67
  4. Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function. (PMID: 19359404) Dutheil F. … Loriot M.A. (Drug Metab. Dispos. 2009) 23 67
  5. Characterization and expression of extrahepatic CYP2S1. (PMID: 19368491) Deb S. … Bandiera S.M. (Expert Opin Drug Metab Toxicol 2009) 23 67

Products for CYP2A Gene

Sources for CYP2A Gene

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