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Aliases for CYP2A Gene

Aliases for CYP2A Gene

  • Cytochrome P450, Family 2, Subfamily A 2 3
  • Cytochrome P450, Subfamily IIA (Phenobarbital-Inducible) 2 3
  • P450C2A 3
  • P450C2 3
  • P450PB 3
  • CYP2F1 6
  • CYP1 3
  • CYP2 3

External Ids for CYP2A Gene

Previous HGNC Symbols for CYP2A Gene

  • CYP1

Previous GeneCards Identifiers for CYP2A Gene

  • GC00U921689
  • GC19P041315

Summaries for CYP2A Gene

Entrez Gene Summary for CYP2A Gene

  • The cytochrome P450 superfamily of enzymes are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP2 gene cluster on chromosome 19q13.2 includes several genes and pseudogenes from the CYP2A, CYP2B, and CYP2F subfamilies. [provided by RefSeq, Jul 2008]

GeneCards Summary for CYP2A Gene

CYP2A (Cytochrome P450, Family 2, Subfamily A) is a Genetic Locus. Diseases associated with CYP2A include coumarin resistance and nicotine dependence, protection against. Among its related pathways are Metabolism and Biological oxidations.

Gene Wiki entry for CYP2A Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP2A Gene

Genomics for CYP2A Gene

Genomic Location for CYP2A Gene

Orientation:
Unknown strand

Genomic View for CYP2A Gene

Cytogenetic band:

RefSeq DNA sequence for CYP2A Gene

No data available for Regulatory Elements for CYP2A Gene

Proteins for CYP2A Gene

Post-translational modifications for CYP2A Gene

No Post-translational modifications

No data available for DME Specific Peptides for CYP2A Gene

Domains for CYP2A Gene

Gene Families for CYP2A Gene

HGNC:
  • CYP :Cytochrome P450s

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CYP2A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CYP2A Gene

Function for CYP2A Gene

Molecular function for CYP2A Gene

GENATLAS Biochemistry: cytochrome P450,subfamily IIA (phenobarbital-inducible)

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CYP2A Gene

Localization for CYP2A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CYP2A Gene

Compounds for CYP2A Gene

(2) Novoseek inferred chemical compound relationships for CYP2A Gene

Compound -log(P) Hits PubMed IDs
phenobarbital 55.7 4
coumarin 44.6 3
genes like me logo Genes that share compounds with CYP2A: view

Transcripts for CYP2A Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CYP2A Gene

No ASD Table

Relevant External Links for CYP2A Gene

ECgene alternative splicing isoforms for
CYP2A

No data available for mRNA/cDNA for CYP2A Gene

Expression for CYP2A Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for CYP2A Gene

Orthologs for CYP2A Gene

No data available for Orthologs and Evolution for CYP2A Gene

Paralogs for CYP2A Gene

No data available for Paralogs for CYP2A Gene

Variants for CYP2A Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CYP2A Gene

Disorders for CYP2A Gene

Relevant External Links for CYP2A

Genetic Association Database (GAD)
CYP2A
Human Genome Epidemiology (HuGE) Navigator
CYP2A
genes like me logo Genes that share disorders with CYP2A: view

No data available for UniProtKB/Swiss-Prot for CYP2A Gene

Publications for CYP2A Gene

  1. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. (PMID: 15128046) Nelson D.R. … Nebert D.W. (Pharmacogenetics 2004) 2 3
  2. Analysis of CYP2A contributions to metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human peripheral lung microsomes. (PMID: 17717079) Brown P.J. … Massey T.E. (Drug Metab. Dispos. 2007) 3
  3. Homologous unequal cross-over within the human CYP2A gene cluster as a mechanism for the deletion of the entire CYP2A6 gene associated with the poor metabolizer phenotype. (PMID: 10423536) Nunoya K. … Kamataki T. (J. Biochem. 1999) 48
  4. Possible role of cytochromes P450 in lupus erythematosus and related disorders. (PMID: 7704004) McKinnon R.A. … Nebert D.W. (Lupus 1994) 23
  5. Differential protein binding and transcriptional activities of HNF-4 elements in three closely related CYP2C genes. (PMID: 7772258) Chen D. … Kemper B. (DNA Cell Biol. 1994) 23

Products for CYP2A Gene

Sources for CYP2A Gene

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