Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CYP27C1 Gene

protein-coding   GIFtS: 51
GCID: GC02M127941

Cytochrome P450, Family 27, Subfamily C, Polypeptide 1

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Cytochrome P450, Family 27, Subfamily C, Polypeptide 11 2
Cytochrome P450 27C12
Cytochrome P450, Family 27, Subfamily C, Polypeptide 132
EC 1.14.-.-3

External Ids:    HGNC: 334801   Entrez Gene: 3397612   Ensembl: ENSG000001866847   UniProtKB: Q4G0S43   

Export aliases for CYP27C1 gene to outside databases

Previous GC identifers: GC02M127658 GC02M120248


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for CYP27C1 Gene:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids
and other lipids. (provided by RefSeq, Jul 2008)

GeneCards Summary for CYP27C1 Gene:
CYP27C1 (cytochrome P450, family 27, subfamily C, polypeptide 1) is a protein-coding gene. GO annotations related to this gene include electron carrier activity and heme binding. An important paralog of this gene is CYP19A1.

Gene Wiki entry for CYP27C1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CYP27C1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCYP27C1 promoter sequence
   Search Chromatin IP Primers for CYP27C1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CYP27C1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q14.3   Ensembl cytogenetic band:  2q14.3   HGNC cytogenetic band: 2q14.3

CYP27C1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CYP27C1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M127941:  view genomic region     (about GC identifiers)

Start:
127,941,412 bp from pter      End:
127,977,654 bp from pter
Size:
36,243 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: C27C1_HUMAN, Q4G0S4 (See protein sequence)
Recommended Name: Cytochrome P450 27C1  
Size: 372 amino acids; 42632 Da
Cofactor: Heme group (By similarity)
Secondary accessions: Q6ZNI7

Explore the universe of human proteins at neXtProt for CYP27C1: NX_Q4G0S4

Explore proteomics data for CYP27C1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys128
  • Modification sites at PhosphoSitePlus

  • See CYP27C1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001001665.3  
    ENSEMBL proteins: 
     ENSP00000334128   ENSP00000387198  

    CYP27C1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CYP27C1
    OriGene Protein Over-expression Lysate for CYP27C1
    OriGene MassSpec for CYP27C1
    OriGene Custom Protein Services for CYP27C1
    GenScript Custom Purified and Recombinant Proteins Services for CYP27C1
    Novus Biologicals CYP27C1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CYP27C1

     
    Search eBioscience for Proteins for CYP27C1 

     
    antibodies-online proteins for CYP27C1 

     
    Search antibodies-online for peptides for CYP27C1

    CYP27C1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CYP27C1
    Novus Biologicals CYP27C1 Antibody
    Abcam antibodies for CYP27C1
    Cloud-Clone Corp. Antibodies for CYP27C1
    ThermoFisher Antibodies for CYP27C1
    antibodies-online antibodies for CYP27C1 (3 products) 

    CYP27C1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CYP27C1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CYP27C1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CYP27C1
    Cloud-Clone Corp. CLIAs for CYP27C1
    Search eBioscience for ELISAs for CYP27C1 
    antibodies-online kits for CYP27C1 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    CYP: Cytochrome P450s

    IUPHAR Guide to PHARMACOLOGY protein family classification: CYP27C1
    CYP24, CYP26 and CYP27 families

    3 InterPro protein domains:
     IPR001128 Cyt_P450
     IPR017972 Cyt_P450_CS
     IPR002401 Cyt_P450_E_grp-I

    Graphical View of Domain Structure for InterPro Entry Q4G0S4

    ProtoNet protein and cluster: Q4G0S4

    UniProtKB/Swiss-Prot: C27C1_HUMAN, Q4G0S4
    Similarity: Belongs to the cytochrome P450 family


    Find genes that share domains with CYP27C1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Enzyme Number (IUBMB): EC 1.14.-.-1

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004497monooxygenase activity IEA--
    GO:0005506iron ion binding IEA--
    GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA--
    GO:0020037heme binding IEA--
         
    Find genes that share ontologies with CYP27C1           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CYP27C1

    miRNA
    Products:
        
    miRTarBase miRNAs that target CYP27C1:
    hsa-mir-335-5p (MIRT017938)

    Block miRNA regulation of human, mouse, rat CYP27C1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CYP27C1:
    hsa-miR-144 hsa-miR-642a
    SwitchGear 3'UTR luciferase reporter plasmidCYP27C1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CYP27C1
    Predesigned siRNA for gene silencing in human, mouse, rat CYP27C1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CYP27C1

    Clone
    Products:
         
    OriGene clones in human, mouse for CYP27C1 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CYP27C1 (NM_001001665)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CYP27C1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP27C1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CYP27C1
    Browse ESI BIO Cell Lines and PureStem Progenitors for CYP27C1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP27C1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    C27C1_HUMAN, Q4G0S4: Membrane (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    cytosol1
    extracellular1
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane IEA--

    Find genes that share ontologies with CYP27C1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for CYP27C1 About    
    See pathways by source

    SuperPathContained pathways About
    1Cytochrome P450 - arranged by substrate type
    cytochrome P4500.74
    2Biological oxidations
    metapathway biotransformation0.42


    2 BioSystems Pathways for CYP27C1
        cytochrome P450
    metapathway biotransformation


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CYP27C1
    Interactions:

        Search GeneGlobe Interaction Network for CYP27C1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for CYP27C1 (ENSP000003341284) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DNAJC17ENSP000002204964STRING: ENSP00000220496
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0055114oxidation-reduction process ----

    Find genes that share ontologies with CYP27C1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CYP27C1 (C27C1)

    1 HMDB Compound for CYP27C1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Heme(protoporphyrinato)iron (see all 19)14875-96-8--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CYP27C1 gene: 
    NM_001001665.3  

    Unigene Cluster for CYP27C1:

    Cytochrome P450, family 27, subfamily C, polypeptide 1
    Hs.407639  [show with all ESTs]
    Unigene Representative Sequence: BC039307
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000335247(uc002tod.2 uc021vnn.1) ENST00000409327
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CYP27C1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CYP27C1:
    hsa-miR-144 hsa-miR-642a
    SwitchGear 3'UTR luciferase reporter plasmidCYP27C1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CYP27C1
    Predesigned siRNA for gene silencing in human, mouse, rat CYP27C1
    Clone
    Products:
         
    OriGene clones in human, mouse for CYP27C1 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CYP27C1 (NM_001001665)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CYP27C1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP27C1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CYP27C1
    OriGene qSTAR qPCR primer pairs in human, mouse for CYP27C1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CYP27C1
      QuantiTect SYBR Green Assays in human, mouse, rat CYP27C1
      QuantiFast Probe-based Assays in human, mouse, rat CYP27C1

    Additional mRNA sequence: 

    AK131190.1 BC039307.1 

    2 DOTS entries:

    DT.91720197  DT.97797836 

    8 AceView cDNA sequences:

    AA423992 BM562765 AK131190 BC039307 NM_001001665 BI459427 BQ277249 BX478822 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CYP27C1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACATTATGCT
    CYP27C1 Expression
    About this image

    CYP27C1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CYP27C1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.407639
        Custom PCR Arrays for CYP27C1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CYP27C1
    OriGene qSTAR qPCR primer pairs in human, mouse for CYP27C1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CYP27C1
    QuantiTect SYBR Green Assays in human, mouse, rat CYP27C1
    QuantiFast Probe-based Assays in human, mouse, rat CYP27C1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP27C1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for CYP27C1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia CYP27C11 cytochrome P450, family 27, subfamily C, polypeptide more 87.28(n)
    89.78(a)
      483869  XM_005631885.1  XP_005631942.1 
    chicken
    (Gallus gallus)
    Aves CYP27C11 cytochrome P450, family 27, subfamily C, polypeptide more 75.72(n)
    80.91(a)
      424227  XM_422077.3  XP_422077.2 
    lizard
    (Anolis carolinensis)
    Reptilia CYP27C16
    cytochrome P450, family 27, subfamily C, polypepti...
    49(a)
    1 ↔ 1
    GL343344.1(759446-799620)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.54502 Xenopus laevis transcribed sequence with weak similarity more 74.97(n)    BX850857.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.113802 Transcribed sequence with weak similarity to protein more 76.19(n)    BG305152.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta sad6
    shadow
    16(a)
    1 → many
    3R(7702957-7705476)


    ENSEMBL Gene Tree for CYP27C1 (if available)
    TreeFam Gene Tree for CYP27C1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CYP27C1 gene
    CYP19A12  CYP11B12  CYP24A12  CYP46A12  CYP11B22  CYP27B12  CYP11A12  CYP27A12  
    6 SIMAP similar genes for CYP27C1 using alignment to 1 protein entry:     C27C1_HUMAN:
    CYP27A1    CYP27B1    CYP3A5    CYP24A1    CYP11B2    CYP11B1

    Find genes that share paralogs with CYP27C1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CYP27C1 (see all 636)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1407333691,2
    C--127440174(+) TCTAA-/CCCAAC 1 -- ds50010--------
    rs1130204431,2
    C,F--127440181(+) AACCCC/TCCTTT 1 -- ds50011Minor allele frequency- T:0.50WA 2
    rs355779921,2
    C,F--127440508(+) CTCTCC/TGCAGA 1 -- ds50018Minor allele frequency- T:0.37NA WA EA 368
    rs1148905491,2
    F--127440543(+) GGTAAA/GAGCAA 1 -- ds50011Minor allele frequency- G:0.01WA 118
    rs1511991891,2
    --127440591(+) TCAGTA/CTTTTG 1 -- ds50010--------
    rs1402539941,2
    C--127440700(+) ACAACA/TTCTGC 1 -- ut310--------
    rs1820820271,2
    --127440734(+) CCCGCA/GGCCTC 1 -- ut310--------
    rs1503768251,2
    C--127440742(+) CTCCCC/GACCTT 1 -- ut310--------
    rs1859106401,2
    --127440826(+) CAGCCA/CTAAAC 1 -- ut310--------
    rs1995943311,2
    C--127440883(-) GTTATG/TTTTTA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CYP27C1 (127941412 - 127977654 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CYP27C1:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv1245e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CYP27C1
    DNA2.0 Custom Variant and Variant Library Synthesis for CYP27C1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease from the University of Copenhagen DISEASES database for CYP27C1:
    Osteonecrosis

    Find genes that share disorders with CYP27C1           About GenesLikeMe

    Genetic Association Database (GAD): CYP27C1

    Export disorders for CYP27C1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CYP27C1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with CYP27C1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    2. A genome-wide association study of self-rated health. (PubMed id 20707712)1 Mosing M.A....Martin N.G. (Twin Res Hum Genet 2010)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    4. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. (PubMed id 15128046)1 Nelson D.R....Nebert D.W. (Pharmacogenetics 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 339761 HGNC: 33480 AceView: FLJ16008 Ensembl:ENSG00000186684 euGenes: HUgn339761
    ECgene: CYP27C1 H-InvDB: CYP27C1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CYP27C1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CYP27C1 gene:
    Search GeneIP for patents involving CYP27C1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CYP27C1  
     OriGene qPCR primer pairs and template standards for CYP27C1   OriGene Protein Over-expression Lysate for CYP27C1  
     OriGene MassSpec for CYP27C1   OriGene clones in human, mouse for CYP27C1  
     OriGene qSTAR qPCR primer pairs in human, mouse for CYP27C1   OriGene Purified Protein for CYP27C1  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CYP27C1   OriGene Custom Protein Services for CYP27C1  

     
     
     Block miRNA regulation of human, mouse, rat CYP27C1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CYP27C1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CYP27C1 Predesigned siRNA for gene silencing in human, mouse, rat CYP27C1
     QuantiFast Probe-based Assays in human, mouse, rat CYP27C1 QuantiTect SYBR Green Assays in human, mouse, rat CYP27C1
     Custom PCR Arrays for CYP27C1 Search Chromatin IP Primers for CYP27C1
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CYP27C1  Search GeneGlobe Interaction Network for CYP27C1
     Search Regulatory tfbs for CYP27C1
     GenScript Custom Purified and Recombinant Proteins Services for CYP27C1 GenScript cDNA clones with any tag delivered in your preferred vector for CYP27C1
     GenScript Custom Assay Services for CYP27C1 GenScript Custom overexpressing Cell Line Services for CYP27C1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CYP27C1 (C27C1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CYP27C1 antibodies
     CYP27C1 lysates
     Antibodies for CYP27C1
     See all of Abcam's Antibodies, Kits and Proteins for CYP27C1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CYP27C1
     Antibodies for CYP27C1
     ELISAs for CYP27C1
     CLIAs for CYP27C1



     Browse ESI BIO Cell Lines and PureStem Progenitors for CYP27C1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP27C1
     SwitchGear 3'UTR luciferase reporter plasmids for CYP27C1
     SwitchGear Promoter luciferase reporter plasmids for CYP27C1
     ThermoFisher Antibodies for CYP27C1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP27C1
     Browse compounds at ApexBio
     Search Addgene for plasmids for CYP27C1
      Search eBioscience for proteins for CYP27C1
      Search eBioscience for elisas for CYP27C1
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for CYP27C1
     antibodies-online antibodies for CYP27C1 (3 products)
     antibodies-online kits for CYP27C1 (2 products)
      Search antibodies-online for peptides for CYP27C1
     antibodies-online proteins for CYP27C1
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CYP27C1 gene at Home site.
    Version: 3.12.248 16 Nov 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4