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Aliases for CYP21A1P Gene

Aliases for CYP21A1P Gene

  • Cytochrome P450, Family 21, Subfamily A, Polypeptide 1 Pseudogene 2 3
  • Cytochrome P450, Subfamily XXIA (Steroid 21-Hydroxylase), Polypeptide 1 Pseudogene 2 3
  • Cytochrome P450, Subfamily XXI (Steroid 21-Hydroxylase) Pseudogene 3
  • P450c21A 3
  • CYP21A 3
  • CYP21P 3

External Ids for CYP21A1P Gene

Previous HGNC Symbols for CYP21A1P Gene

  • CYP21P
  • CYP21A

Previous GeneCards Identifiers for CYP21A1P Gene

  • GC06U990020
  • GC06P031744
  • GC06P032080
  • GC06P031972
  • GC06P031983
  • GC06P032009

Summaries for CYP21A1P Gene

GeneCards Summary for CYP21A1P Gene

CYP21A1P (Cytochrome P450, Family 21, Subfamily A, Polypeptide 1 Pseudogene) is a Pseudogene. Diseases associated with CYP21A1P include c4b deficiency and juvenile rheumatoid arthritis.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CYP21A1P Gene

Genomics for CYP21A1P Gene

Genomic Location for CYP21A1P Gene

32,005,636 bp from pter
32,008,909 bp from pter
3,274 bases
Plus strand

Genomic View for CYP21A1P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CYP21A1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for Regulatory Elements for CYP21A1P Gene

Proteins for CYP21A1P Gene

Post-translational modifications for CYP21A1P Gene

No Post-translational modifications

No data available for DME Specific Peptides for CYP21A1P Gene

Domains for CYP21A1P Gene

Gene Families for CYP21A1P Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CYP21A1P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CYP21A1P Gene

Function for CYP21A1P Gene

Molecular function for CYP21A1P Gene

GENATLAS Biochemistry:
cytochrome P450,family XXI A1,pseudogene,included in the YA sequence,in the same orientation

miRNA for CYP21A1P Gene

miRTarBase miRNAs that target CYP21A1P

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for CYP21A1P Gene

Localization for CYP21A1P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CYP21A1P Gene

Pathways for CYP21A1P Gene

SuperPathways for CYP21A1P Gene

No Data Available

Interacting Proteins for CYP21A1P Gene

Gene Ontology (GO) - Biological Process for CYP21A1P Gene


No data available for Pathways by source for CYP21A1P Gene

Drugs for CYP21A1P Gene

(5) Novoseek inferred chemical compound relationships for CYP21A1P Gene

Compound -log(P) Hits PubMed IDs
steroid 73.9 15
bgl ii 55.9 1
oligonucleotide 7.66 2
threonine 2.62 1
serine 0 1
genes like me logo Genes that share compounds with CYP21A1P: view

Transcripts for CYP21A1P Gene

mRNA/cDNA for CYP21A1P Gene

(14) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CYP21A1P Gene

No ASD Table

Relevant External Links for CYP21A1P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CYP21A1P Gene

mRNA expression in normal human tissues for CYP21A1P Gene

mRNA differential expression in normal tissues according to GTEx for CYP21A1P Gene

This gene is overexpressed in Adrenal Gland (30.7) and Liver (6.0).
genes like me logo Genes that share expressions with CYP21A1P: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for CYP21A1P Gene

Orthologs for CYP21A1P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for CYP21A1P Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Cyp21a1 16
Species with no ortholog for CYP21A1P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CYP21A1P Gene

Gene Tree for CYP21A1P (if available)
Gene Tree for CYP21A1P (if available)

Paralogs for CYP21A1P Gene

No data available for Paralogs for CYP21A1P Gene

Variants for CYP21A1P Gene

Sequence variations from dbSNP and Humsavar for CYP21A1P Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs1079995 -- 32,006,551(-) AGAGG(A/C/G/T)GAGGC intron-variant
rs3130496 -- 32,003,700(-) TCTTT(G/T)CCTGG upstream-variant-2KB, intron-variant
rs3891366 -- 32,006,196(-) GAGGC(A/C/G/T)GAGGT nc-transcript-variant, intron-variant
rs4959020 -- 32,005,403(+) CTGCA(C/T)GGGTG upstream-variant-2KB, intron-variant
rs4959082 -- 32,005,943(+) GTGAC(A/G)GAGAG nc-transcript-variant, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CYP21A1P Gene

Variant ID Type Subtype PubMed ID
dgv1928e1 CNV Complex 17122850
nsv428141 CNV Gain+Loss 18775914
dgv1929e1 CNV Complex 17122850
dgv6604n71 CNV Loss 21882294
nsv284 CNV Loss 15895083
nsv5247 CNV Loss 18451855
dgv6607n71 CNV Loss 21882294
dgv6608n71 CNV Gain 21882294
dgv6610n71 CNV Gain 21882294
dgv6612n71 CNV Loss 21882294
dgv6613n71 CNV Loss 21882294
dgv6614n71 CNV Gain 21882294
dgv6615n71 CNV Gain 21882294
dgv6616n71 CNV Gain+Loss 21882294
esv28110 CNV Gain+Loss 19812545
dgv6617n71 CNV Gain+Loss 21882294
nsv10824 CNV Gain+Loss 18304495
dgv6620n71 CNV Gain 21882294
nsv819957 CNV Loss 19587683
dgv6621n71 CNV Gain 21882294
dgv6622n71 CNV Gain+Loss 21882294
nsv884617 CNV Gain 21882294
dgv20n31 CNV Duplication 19718026
nsv884626 CNV Loss 21882294
nsv884627 CNV Loss 21882294
dgv6623n71 CNV Loss 21882294
dgv6624n71 CNV Loss 21882294
dgv6625n71 CNV Gain 21882294
nsv823506 CNV Loss 20364138
nsv823507 CNV Loss 20364138
esv32938 CNV Gain 17666407
dgv6626n71 CNV Gain+Loss 21882294
dgv6627n71 CNV Gain 21882294
dgv6628n71 CNV Loss 21882294
dgv6629n71 CNV Loss 21882294
nsv884657 CNV Gain 21882294
dgv6630n71 CNV Gain+Loss 21882294
dgv6631n71 CNV Loss 21882294
nsv823508 CNV Gain 20364138
nsv884663 CNV Gain 21882294
nsv884664 CNV Gain 21882294

Relevant External Links for CYP21A1P Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CYP21A1P Gene

Disorders for CYP21A1P Gene

(3) Novoseek inferred disease relationships for CYP21A1P Gene

Disease -log(P) Hits PubMed IDs
adrenal hyperplasia congenital 94.1 4
adrenal hyperplasia 61.6 2
lupus erythematosus systemic 0 1

Relevant External Links for CYP21A1P

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with CYP21A1P: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES and Genatlas for CYP21A1P Gene

Publications for CYP21A1P Gene

  1. Microconversion between CYP21A2 and CYP21A1P promoter regions causes the nonclassical form of 21-hydroxylase deficiency. (PMID: 17666484) AraA_jo R.S. … Bachega T.A. (J. Clin. Endocrinol. Metab. 2007) 3 23
  2. Structure of human steroid 21-hydroxylase genes. (PMID: 3487786) White P.C. … Dupont B. (Proc. Natl. Acad. Sci. U.S.A. 1986) 2 3
  3. The gene founder effect of two spontaneous mutations in ethnic Chinese (Taiwanese) CAH patients with 21-hydroxylase deficiency. (PMID: 19201236) Lee Y.J. … Lee H.H. (Mol. Genet. Metab. 2009) 3 48
  4. Linkage analysis of the C4A/C4B copy number variation and polymorphisms of the adjacent steroid 21-hydroxylase gene in a healthy population. (PMID: 19505723) Blasko B. … Szilagyi A. (Mol. Immunol. 2009) 3 48
  5. Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes. (PMID: 15036125) Schlade-Bartusiak K. … Sasiadek M. (Mutat. Res. 2004) 3 48

Products for CYP21A1P Gene

Sources for CYP21A1P Gene

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