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CYP1A1 Gene

protein-coding   GIFtS: 73
GCID: GC15M075011

Cytochrome P450, Family 1, Subfamily A, Polypeptide 1

(Previous names: cytochrome P450, subfamily I (aromatic compound-inducible),...)
(Previous symbol: CYP1)
Microbiology & Infectious Diseases Congress
  See related diseases

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Cytochrome P450, Family 1, Subfamily A, Polypeptide 11 2     CP112
CYP11 2 5     P1-4502
Cytochrome P450, Subfamily I (Aromatic Compound-Inducible), Polypeptide 11 2     P450-C2
Cytochrome P450 Form 62 3     P450DX2
Cytochrome P450-C2 3     Aryl Hydrocarbon Hydroxylase2
Cytochrome P450-P12 3     Cytochrome P1-450, Dioxin-Inducible2
CYPIA12 3     Cytochrome P450 1A12
EC 8     Flavoprotein-Linked Monooxygenase2
AHH2     Xenobiotic Monooxygenase2

External Ids:    HGNC: 25951   Entrez Gene: 15432   Ensembl: ENSG000001404657   OMIM: 1083305   UniProtKB: P047983   

Export aliases for CYP1A1 gene to outside databases

Previous GC identifers: GC15M068848 GC15M068126 GC15M072587 GC15M072727 GC15M072798 GC15M051809

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CYP1A1 Gene:
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins
are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol,
steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by
some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous
substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has
been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from
CYP1A1 on chromosome 15. (provided by RefSeq, Jul 2008)

GeneCards Summary for CYP1A1 Gene: 
CYP1A1 (cytochrome P450, family 1, subfamily A, polypeptide 1) is a protein-coding gene. Diseases associated with CYP1A1 include basal cell carcinoma, multiple, and oral cancer, and among its related super-pathways are Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) and Cytochrome P450 - arranged by substrate type. GO annotations related to this gene include iron ion binding and enzyme binding. An important paralog of this gene is CYP1A2.

UniProtKB/Swiss-Prot: CP1A1_HUMAN, P04798
Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is
involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated
compounds, including steroids, fatty acids, and xenobiotics

Gene Wiki entry for CYP1A1 (Cytochrome P450, family 1, member A1) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NT_010194.17  NC_018926.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CYP1A1 gene promoter:
         GR   C/EBPbeta   p53   SREBP-1c   Bach2   SREBP-1b   HNF-4alpha1   MZF-1   SREBP-1a   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): CYP1A1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CYP1A1

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYP1A1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q24.1   Ensembl cytogenetic band:  15q24.1   HGNC cytogenetic band: 15q24.1

CYP1A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CYP1A1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M075011:  view genomic region     (about GC identifiers)

75,011,883 bp from pter      End:
75,017,951 bp from pter
6,069 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CP1A1_HUMAN, P04798 (See protein sequence)
Recommended Name: Cytochrome P450 1A1  
Size: 512 amino acids; 58165 Da
Cofactor: Heme group
Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral
membrane protein
1 PDB 3D structure from and Proteopedia for CYP1A1:
4I8V (3D)    
Secondary accessions: Q53G18

Explore the universe of human proteins at neXtProt for CYP1A1: NX_P04798

Explore proteomics data for CYP1A1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P04798

  • 4/25 DME Specific Peptides for CYP1A1 (P04798) (see all 25)

    CYP1A1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CYP1A1 Protein Expression
    REFSEQ proteins: NP_000490.1  
    ENSEMBL proteins: 
     ENSP00000369050   ENSP00000456585   ENSP00000378489   ENSP00000455340   ENSP00000457668  
     ENSP00000455051   ENSP00000455846   ENSP00000378488  
    Reactome Protein details: P04798
    Human Recombinant Protein Products for CYP1A1: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CYP1A1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005739mitochondrion IEA--
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0043231intracellular membrane-bounded organelle ----

    CYP1A1 for ontologies           About GeneDecksing

    CYP1A1 Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of CYP1A1
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CYP: Cytochrome P450s

    IUPHAR Guide to PHARMACOLOGY protein family classification: CYP1A1 
    CYP1 family

    4 InterPro protein domains:
     IPR001128 Cyt_P450
     IPR017972 Cyt_P450_CS
     IPR002401 Cyt_P450_E_grp-I
     IPR008066 Cyt_P450_E_grp-I_CYP1

    Graphical View of Domain Structure for InterPro Entry P04798

    ProtoNet protein and cluster: P04798

    2 Blocks protein domains:
    IPB002401 E-class P450 group I signature
    IPB008066 CYP1A P450 family signature

    UniProtKB/Swiss-Prot: CP1A1_HUMAN, P04798
    Similarity: Belongs to the cytochrome P450 family

    CYP1A1 for domains           About GeneDecksing

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CP1A1_HUMAN, P04798
    Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is
    involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated
    compounds, including steroids, fatty acids, and xenobiotics
    Catalytic activity: RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O
    Induction: By 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

         Genatlas biochemistry entry for CYP1A1:
    cytochrome p450,family I (polycytic aromatic compound-inducible),member A1 (see CYP1@),associated with
    susceptibility to lung squamous cell carcinoma and to childhood acute lymphoblastic leukemia (in association with
    deletion of GSTM1)

         Enzyme Number (IUBMB): EC 2

         Gene Ontology (GO): 5/17 molecular function terms (GO ID links to tree view) (see all 17):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004497monooxygenase activity ----
    GO:0005506iron ion binding IEA--
    GO:0005515protein binding ----
    GO:0008395steroid hydroxylase activity IEA--
    CYP1A1 for ontologies           About GeneDecksing

         9 MGI mutant phenotypes (inferred from 7 alleles(MGI details for Cyp1a1):
     cardiovascular system  growth/size  hematopoietic system  homeostasis/metabolism  immune system 
     liver/biliary system  mortality/aging  no phenotypic analysis  normal 

    CYP1A1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for CYP1A1: Cyp1a1tm1.1Dwn Cyp1a2/Cyp1a1Cyp1a2/tm2Dwn Cyp1a2/Cyp1a1Cyp1a2/tm1.1Bra

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CYP1A1 
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CYP1A1
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    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CYP1A1
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    Gene Editing
    DNA2.0 Custom Protein Engineering Service for CYP1A1
    Sirion Biotech Customized adenovirus for overexpression of CYP1A1

    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CYP1A1 (see all 9)
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    GenScript: all cDNA clones in your preferred vector: CYP1A1 (NM_000499)
    Sino Biological Human cDNA Clone for CYP1A1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CYP1A1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYP1A1
    Sirion Biotech Customized lentivirus for stable overexpression of CYP1A1 
                         Customized lentivirus expression plasmids for stable overexpression of CYP1A1 

    Cell Line
    GenScript Custom overexpressing Cell Line Services for CYP1A1
    Search LifeMap BioReagents cell lines for CYP1A1
    In Situ Assay

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP1A1

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CYP1A1 About   (see all 21)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
    Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)0.55
    Benzo[a]pyrene metabolism0.43
    Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)0.55
    Amodiaquine Pathway, Pharmacokinetics0.38
    Warfarin Pathway, Pharmacokinetics0.45
    2Cytochrome P450 - arranged by substrate type
    Cytochrome P450 - arranged by substrate type0.75
    Phase 1 - Functionalization of compounds0.74
    cytochrome P4500.75
    3Acetaminophen metabolism
    Acetaminophen metabolism0.43
    2-Naphthylamine and 2-Nitronaphtalene metabolism0.32
    Acetaminophen Pathway, Pharmacokinetics0.43
    Metabolism of lipids and lipoproteins0.34
    Metabolic pathways0.40
    5Tamoxifen metabolism
    Tamoxifen metabolism0.68
    Estradiol metabolism0.52

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    5/7 EMD Millipore Pathways for CYP1A1 (see all 7)
        Androstenedione and testosterone biosynthesis and metabolism p.1
    Estradiol metabolism
    2-Naphthylamine and 2-Nitronaphtalene metabolism
    Retinol metabolism
    Naphthalene metabolism

    5/7 GeneGo (Thomson Reuters) Pathways for CYP1A1 (see all 7)
        Estradiol metabolism
    Retinol metabolism
    Naphthalene metabolism
    2-Naphthylamine and 2-Nitronaphtalene metabolism
    Benzo[a]pyrene metabolism

    5/9 BioSystems Pathways for CYP1A1 (see all 9)
        cytochrome P450
    Oxidative Stress
    Tamoxifen metabolism
    Estrogen metabolism
    Benzo(a)pyrene metabolism

    5/12        Reactome Pathways for CYP1A1 (see all 12)
        Cytochrome P450 - arranged by substrate type
    Arachidonic acid metabolism
    Fatty acid, triacylglycerol, and ketone body metabolism

    5/6 PharmGKB Pathways for CYP1A1 (see all 6)
        Acetaminophen Pathway, Pharmacokinetics
    Amodiaquine Pathway, Pharmacokinetics
    Erlotinib Pathway, Pharmacokinetics
    Estrogen Metabolism Pathway
    Gefitinib Pathway, Pharmacokinetics

    5/7         Kegg Pathways  (Kegg details for CYP1A1) (see all 7):
        Steroid hormone biosynthesis
    Tryptophan metabolism
    Retinol metabolism
    Metabolism of xenobiotics by cytochrome P450
    Metabolic pathways

    CYP1A1 for pathways           About GeneDecksing


        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CYP1A1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/90 Interacting proteins for CYP1A1 (P047983 ENSP000003690504) via UniProtKB, MINT, STRING, and/or I2D (see all 90)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CYB5AP001673, ENSP000003416254I2D: score=1 STRING: ENSP00000341625
    HSP90AA1P079003I2D: score=1 
    HSPA4P349323I2D: score=1 
    AKR1C1ENSP000003702544STRING: ENSP00000370254
    AKR1C3ENSP000003699274STRING: ENSP00000369927
    About this table

    Gene Ontology (GO): 5/48 biological process terms (GO ID links to tree view) (see all 48):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001666response to hypoxia IEA--
    GO:0001889liver development ----
    GO:0006778porphyrin-containing compound metabolic process IEA--
    GO:0006805xenobiotic metabolic process TAS--
    GO:0006950response to stress ----

    CYP1A1 for ontologies           About GeneDecksing

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CYP1A1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CYP1A1 (CP1A1)

    10/54 HMDB Compounds for CYP1A1 (see all 54)    About this table
    CompoundSynonyms CAS #PubMed Ids
    Melatonin5-Methoxy-N-acetyltryptamine (see all 23)73-31-419919601
    10-HETE10-hydroxyeicosa-all-cis-5,8,11,14-tetraenoate (see all 2)167697-52-1--
    11,12,15-THETA11,12,15-Trihydroxyicosatrienoic acid (see all 5)----
    11,12-Epoxyeicosatrienoic acid10-(3-(2-octenyl)oxiranyl)-5,8-Decadienoic acid (see all 15)81276-02-0--
    11,14,15-THETA(5Z,8Z,12E)-11,14,15-Trihydroxyeicosa-5,8,12-trienoic acid (see all 8)----
    11H-14,15-EETA14,15-Ep-11-HETrE (see all 11)219535-29-2--
    11beta-Hydroxytestosterone11beta,17beta-dihydroxyandrost-4-en-3-one 1816-85-9--
    12,13-EpOMEVernolic acid (see all 12)----
    13-HETE13-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoate (see all 2)151910-72-4--
    14,15-Epoxy-5,8,11-eicosatrienoic acid(5Z,8Z,11Z)-14,15-Epoxyicosa-5.8.11-trienoic acid (see all 11)81276-03-1--

    10/90 DrugBank Compounds for CYP1A1 (see all 90)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ErlotinibCP358774 (see all 2)183321-74-6enzymesubstrate17575239 16166415 19733976
    MelatoninMEL (see all 4)73-31-4enzymesubstrate inhibitor19919601 15616152 19934256
    TamoxifenICI-46474 (see all 3)10540-29-1enzymesubstrate12124303 19934256 19515014
    AmiodaroneAmiodarona [INN-Spanish] (see all 5)1951-25-3enzymesubstrate18445370 19934256
    AmlodipineAmlodipine Benzenesulfonate (see all 6)88150-42-9enzymeinhibitor10805063 19934256
    Benzyl alcohol(Hydroxymethyl)benzene (see all 10)100-51-6enzyme--9065730 9726784
    ChlorzoxazoneChloroxazone (see all 3)95-25-0enzymesubstrate15231049 20164110
    Cinnarizine-- 298-57-7enzymesubstrate19934256 19515014
    Dasatinib-- 302962-49-8enzymesubstrate18556438 19733976
    Ellagic Acid-- 476-66-4enzymeinhibitor inducer8024593 19469472

    10/140 Novoseek inferred chemical compound relationships for CYP1A1 gene (see all 140)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tcdd 94 698 8396892 (9), 15630080 (7), 11728381 (6), 9931287 (6) (see all 99)
    ethoxyresorufin 91.1 84 17959138 (4), 8093105 (3), 11599655 (2), 8396892 (1) (see all 67)
    benzo(a)pyrene 89.7 376 18372000 (6), 19330882 (6), 16280210 (6), 10503953 (6) (see all 99)
    alpha-naphthoflavone 88.1 64 1329656 (4), 12628305 (2), 2115161 (2), 1315629 (1) (see all 38)
    3-methylcholanthrene 86.4 193 12941938 (7), 16137816 (4), 17276403 (3), 9465551 (3) (see all 64)
    hydrocarbons 85.2 131 8954573 (2), 17630984 (2), 19362136 (2), 8353849 (2) (see all 99)
    mspi 84.8 71 1284589 (4), 8706015 (3), 8877059 (3), 8983277 (2) (see all 51)
    beta-naphthoflavone 82.9 79 11076701 (3), 12147246 (3), 18502397 (3), 19470599 (3) (see all 36)
    4-methoxyestradiol 79.6 1 10403516 (1)
    benz(a)anthracene 78.8 30 1700499 (4), 8920757 (2), 1358564 (2), 1654865 (2) (see all 14)

    Search CenterWatch for drugs/clinical trials and news about CYP1A1 / CP1A1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CYP1A1 gene: 

    Unigene Cluster for CYP1A1:

    Cytochrome P450, family 1, subfamily A, polypeptide 1
    Hs.72912  [show with all ESTs]
    Unigene Representative Sequence: NM_000499
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000379727(uc002ayq.4 uc010bjy.3) ENST00000567032 ENST00000395049
    ENST00000562201 ENST00000564596(uc010bjz.1) ENST00000569630 ENST00000566503
    ENST00000395048(uc002ayp.4 uc010bju.3 uc010bjv.3 uc010bjw.3 uc010bjx.3)

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYP1A1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYP1A1

    Additional mRNA sequence: 

    AK223108.1 AK223113.1 AK310810.1 AK313880.1 AM233517.1 AM233518.1 AM233519.1 AM233520.1 
    AM236046.1 AM236047.1 AY310359.1 AY871801.1 BC023019.1 K03191.1 M12079.1 

    2 DOTS entries:

    DT.310017  DT.100744671 

    24/52 AceView cDNA sequences (see all 52):

    BQ878741 NM_000499 BQ005861 AL600770 CA423835 AL600919 AW949660 AL600881 
    BC023019 AI417887 AV656441 BU620769 AW451941 BU182605 K03191 CB265483 
    CA439920 M12079 BU941041 AI745534 AL598658 BP353358 BF437793 CA426401 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for CYP1A1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b

    ECgene alternative splicing isoforms for CYP1A1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CYP1A1 expression in normal human tissues (normalized intensities)      CYP1A1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CYP1A1 Expression
    About this image

    CYP1A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     Endothelium (Cardiovascular System)    fully expand to see all 3 entries
             PureStem ES-335, Meso-latp Progenitor
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             PureStem endothelial progenitor 30-MV2-12
     Lung (Respiratory System)
             Basal Cells Respiratory Bronchioles
     Liver (Hepatobiliary System)
             Perivenous Hepatocytes Liver Lobule
     Intestine (Gastrointestinal Tract)

    See CYP1A1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CYP1A1

    SOURCE GeneReport for Unigene cluster: Hs.72912

    UniProtKB/Swiss-Prot: CP1A1_HUMAN, P04798
    Tissue specificity: Lung, lymphocytes and placenta

        SABiosciences Expression via Pathway-Focused PCR Arrays including CYP1A1 (see all 6): 
              Estrogen Receptor Signaling in human mouse rat
              Cancer Drug Resistance in human mouse rat
              Drug Metabolism: Phase I Enzymes in human mouse rat
              Cellular Stress Responses in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat

    OriGene qPCR primer pairs and template standards for CYP1A1
    OriGene qSTAR qPCR primer pairs in human, mouse for CYP1A1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CYP1A1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYP1A1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYP1A1
    In Situ
    Assay Products:

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYP1A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CYP1A1 gene from 8/16 species (see all 16)    About this table
    Organism Taxonomic
    Gene Description Human
    (Mus musculus)
    Mammalia Cyp1a11 , 5 cytochrome P450, family 1, subfamily a, polypeptide more1, 5 82.71(n)1
      9 (31.34 cM)5
    130761  NM_001136059.21  NP_001129531.11 
    (Gallus gallus)
    Aves CYP1A11 cytochrome P450, family 1, subfamily A, polypeptide more 67.06(n)
      396051  NM_205146.1  NP_990477.1 
    (Anolis carolinensis)
    Reptilia --
    (see all 3)
    Uncharacterized protein
    (see all 3)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    African clawed frog
    (Xenopus laevis)
    Amphibia AB022087.12   -- 71.3(n)    AB022087.1 
    (Danio rerio)
    Actinopterygii cyp1a12 cytochrome P450, subfamily I, polypeptide 1 74.16(n)   140634  AB078927.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Cyp18a13 steroid biosynthesis cytochrome P450 32(a)
    (best of 2)
      17D1   --
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons CYP93D11 cytochrome P450, family 93, subfamily D, polypeptide more 41.25(n)
      830580  NM_120772.1  NP_196307.1 
    (Oryza sativa)
    Liliopsida Os06g06136001 hypothetical protein 46.09(n)
      4341526  NM_001064607.1  NP_001058072.1 

    ENSEMBL Gene Tree for CYP1A1 (if available)
    TreeFam Gene Tree for CYP1A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to Build 68)
    About This Section
    Paralogs for CYP1A1 gene
    CYP1A22  CYP1B12  CYP2D7P12  CYP17A12  CYP21A22  
    18/30 SIMAP similar genes for CYP1A1 using alignment to 10 protein entries:     CP1A1_HUMAN (see all proteins) (see all similar genes):
    CYP1A2    CYP1B1    CYP2U1    CYP2S1    CYP4V2    DKFZp686I24235
    CYP2D6    CYP21A2    CYP2A7    CYP2A13    CYP2A6    CYP2C9
    CYP2C8    CYP2R1    CYP2B7    CYP2F1    CYP2J2    CYP2A6V2

    CYP1A1 for paralogs           About GeneDecksing

    1 Pseudogene for CYP1A1

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/294 SNPs in CYP1A1 are shown (see all 294)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    Chr 15 posSequence#AA
    ----see VAR_0169392 R C mis40--------
    ----see VAR_0169382 I N mis40--------
    --55062351(+) AGGGCA/GTAAGT 1 -- ds50010--------
    C,F--55062527(-) CGCAGG/CCACAC 1 -- ds50015Minor allele frequency- C:0.01NS 176
    F--55062576(+) GAGCCT/CGGAGG 1 -- ds50011Minor allele frequency- C:0.39PA 802
    C,F,A,H--55062577(-) CCTCCA/C/TGGGCT 1 -- ds500117NA MN NS WA CSA EA 934
    --55062715(+) TGCTAC/TCTCCT 1 -- ds50010--------
    C--55062779(+) TTAGAC/GGAGTG 1 -- ds50010--------
    --55062780(+) TAGACA/GAGTGA 1 -- ds50010--------
    C,H--55062791(+) TGAATC/TATTTA 1 -- ds500111Minor allele frequency- T:0.00NS EA NA MN 812

    HapMap Linkage Disequilibrium report for CYP1A1 (75011883 - 75017951 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CYP1A1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv904380CNV Loss21882294
    nsv904379CNV Loss21882294
    nsv833055CNV Loss17160897
    nsv817698CNV Gain17921354

    Human Gene Mutation Database (HGMD): CYP1A1

    Locus Specific Mutation Databases (LSDB): CYP1A1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CYP1A1
    DNA2.0 Custom Variant and Variant Library Synthesis for CYP1A1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 108330    OMIM disorders: --

    20/169 diseases for CYP1A1 (see all 169):    About MalaCards
    basal cell carcinoma, multiple    oral cancer    leukoplakia    basal cell carcinoma
    cytochrome p450    lung cancer    oral cavity cancer    cardia cancer
    hidradenitis suppurativa    malignant hypertension    hidradenitis    breast disease
    endometriosis    hepatocellular adenoma    placental choriocarcinoma    laryngitis
    porphyria cutanea tarda    familial prostate cancer    intrahepatic cholestasis of pregnancy    skin cancer

    4 diseases from the University of Copenhagen DISEASES database for CYP1A1:
    Lung cancer     Hepatocellular carcinoma     Breast cancer     Carcinoma

    CYP1A1 for disorders           About GeneDecksing

    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    10/93 Novoseek inferred disease relationships for CYP1A1 gene (see all 93)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    ahh inducibility 87.7 42 8126925 (5), 8609043 (5), 9465551 (5), 9731718 (4) (see all 10)
    cancer lung 68.2 293 9894148 (6), 11778487 (6), 16228113 (6), 10491856 (5) (see all 99)
    genetic susceptibility 61.7 23 18304461 (2), 10698723 (1), 19472123 (1), 20054510 (1) (see all 18)
    chemical carcinogenesis 58 6 12628305 (1), 19573549 (1), 12520071 (1), 11370663 (1) (see all 6)
    cancer 57.9 119 8552885 (3), 15355884 (3), 15805301 (2), 16402077 (2) (see all 91)
    breast cancer 57.1 155 9485019 (6), 20088394 (5), 11408954 (5), 16807674 (4) (see all 79)
    environmental carcinogenesis 56.6 1 18463401 (1)
    oral cancer 46 35 19469619 (5), 17461521 (4), 19160101 (3), 9332761 (3) (see all 10)
    adenocarcinoma lung 43.3 14 17200336 (2), 12824892 (2), 15375499 (2), 11955671 (1) (see all 8)
    carcinoma squamous cell 43.2 41 11778487 (3), 10435155 (2), 7554077 (2), 10793329 (2) (see all 30)

    Genetic Association Database (GAD): CYP1A1
    Human Genome Epidemiology (HuGE) Navigator: CYP1A1 (699 documents)

    Export disorders for CYP1A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CYP1A1 gene, integrated from 9 sources (see all 1872) (see top 10):
    (articles sorted by number of sources associating them with CYP1A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Variation in induced CYP1A1 levels: relationship to CYP1A1, Ah receptor and GSTM1 polymorphisms. (PubMed id 10739168)1, 2, 9 Smart J. and Daly A.K. (2000)
    2. [Relationship between CYP1A1, GSTM1 genetic polymorphisms and susceptibility to esophageal squamous cell carcinoma] (PubMed id 11860825)1, 4, 9 Shao G....Wen B. (2000)
    3. Evidence for increased cytochrome P450 1A1 expression in blood lymphocytes of lung cancer patients. (PubMed id 19632247)1, 4, 9 Shah P.P....Parmar D. (2009)
    4. [Relationship between susceptibility and prognosis of laryngeal cancer and genetic polymorphisms in CYP1A1 and GSTM1] (PubMed id 15127559)1, 4, 9 Li L....Lu H.H. (2004)
    5. CYP1A1 gene polymorphism and risk of epithelial ovarian neoplasm. (PubMed id 12144816)1, 4, 9 Aktas D....Ayhan A. (2002)
    6. Possible risk modification by CYP1A1, GSTM1 and GSTT1 gene polymorphisms in lung cancer susceptibility in a South Indian population. (PubMed id 16228113)1, 4, 9 Sreeja L....Ankathil R. (2005)
    7. [Relationship between CYP1A1 gene polymorphisms and u rinary 1-hydroxypyrene levels in coke oven workers] (PubMed id 19538838)1, 4, 9 Nie J.S....Niu Q. (2009)
    8. CYP1A1 and GSTM1 polymorphisms and oral cancer risk: association studies via evidence-based meta-analyses. (PubMed id 19160101)1, 4, 9 Zhuo W....Chen Z. (2009)
    9. CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility. (PubMed id 18318428)1, 4, 9 Hirata H....Dahiya R. (2008)
    10. Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS. (PubMed id 17852022)1, 4, 9 Ajroud-Driss S....Lukas T.J. (2007)
    11. Polymorphisms of CYP1A1 and GSTM1 genes and susceptibility to oral cancer. (PubMed id 17461521)1, 4, 9 Cha I.H....Park K.K. (2007)
    12. [Association between genetic polymorphisms of metabolic enzymes and susceptibility of colorectal cancer] (PubMed id 16620591)1, 4, 9 Fan C.H....Chen K. (2006)
    13. Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density. (PubMed id 15647817)1, 4, 9 Napoli N....Armamento-Villareal R. (2005)
    14. CYP1A1 polymorphism and risk of gynecological malignancy in Japan. (PubMed id 14675315)1, 4, 9 Sugawara T....Fujimoto S. (2003)
    15. Aromatic DNA adducts and polymorphisms of CYP1A1, NAT2, and GSTM1 in breast cancer. (PubMed id 11872636)1, 4, 9 Firozi P.F....Li D. (2002)
    16. CYP1A1, cigarette smoking, and colon and rectal cancer. (PubMed id 15496536)1, 4, 9 Slattery M.L....Neuhausen S. (2004)
    17. Genetic polymorphisms and transcriptional pattern analysis of CYP1A1, AhR, GSTM1, GSTP1 and GSTT1 genes in breast cancer. (PubMed id 11408954)1, 4, 9 Dialyna I.A....Spandidos D.A. (2001)
    18. Polymorphisms of the CYP1A1 and GSTM1 genes in relation to individual susceptibility to lung carcinoma in Chinese population. (PubMed id 11406420)1, 4, 9 Chen S....Wu J. (2001)
    19. Association studies of CYP1A1 and GSTM1 polymorphisms with esophageal cancer risk: evidence-based meta-analyses. (PubMed id 19427967)1, 4, 9 Zhuo W.L....Chen Z.T. (2009)
    20. Combination of TNF-RII, CYP1A1 and GSTM1 polymorphism s and the risk of Japanese SLE: findings from the KYSS study. (PubMed id 19561157)1, 4, 9 Horiuchi T....Takahashi H. (2009)
    21. Association between dietary heterocyclic amine levels , genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of colorectal canc er: a hospital-based case-control study in Japan. (PubMed id 19452301)1, 4, 9 Kobayashi M....Tsugane S. (2009)
    22. GSTM1, GSTT1 and CYP1A1 Polymorphisms and Risk of Oral Cancer: a Case-control Study in Jakarta, Indonesia. (PubMed id 19469619)1, 4, 9 Amtha R....Purwanto D. (2009)
    23. Association between dietary heterocyclic amine levels , genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of stomach cancer: a hospital-based case-control study in Japan. (PubMed id 20047124)1, 4, 9 Kobayashi M....Tsugane S. (2009)
    24. Association between polymorphisms in the biometabolism genes CYP1A1, GSTM1, GSTT1 and GSTP1 in bladder cancer. (PubMed id 18979064)1, 4, 9 Grando Syllos Colus I.M. (2008)
    25. [Association of cytochrome P450 genes polymorphisms (CYP1A1 and CYP1A2) with the development of chronic obstructive pulmonary disease in Bashkortostan] (PubMed id 18389617)1, 4, 9 Korytina G.F....Viktorova T.V. (2008)
    26. Cytochrome P450 1A1 (CYP1A1) T3801C and A2455G polymorphisms in breast cancer risk: a meta-analysis. (PubMed id 17427032)1, 4, 9 Chen C....Xie Y. (2007)
    27. [Allelic variants of cytochrome P4501A1 (CYP1A1), glutathione S transferase M1 (GSTM1) polymorphisms and their association with smoking and alcohol consumption as gastric cancer susceptibility biomarkers] (PubMed id 17171211)1, 4, 9 Lee K....Quinones S L. (2006)
    28. Maternal smoking during pregnancy and genetic polymorphisms in the Ah receptor, CYP1A1 and GSTM1 affect infant birth size in Japanese subjects. (PubMed id 16481407)1, 4, 9 Sasaki S....Kishi R. (2006)
    29. Cigarette smoking, cytochrome P4501A1 polymorphisms, and breast cancer among African-American and white women. (PubMed id 15217514)1, 4, 9 Li Y....Conway K. (2004)
    30. CYP1A1 and GSTM1 polymorphic genotypes in patients with prostate cancer in a Turkish population. (PubMed id 15381379)1, 4, 9 Aktas D....Tuncbilek E. (2004)
    31. Ah receptor, CYP1A1, CYP1A2 and CYP1B1 gene polymorphisms are not involved in the risk of recurrent pregnancy loss. (PubMed id 15299091)1, 4, 9 Saijo Y....Kishi R. (2004)
    32. Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north indian population. (PubMed id 15646021)1, 4, 9 Sobti R.C....Janmeja A. (2004)
    33. CYP1A1, GSTM1 and GSTT1 genetic polymorphism is associated with susceptibility to polycystic ovaries in South Indian women. (PubMed id 15333250)1, 4, 9 Babu K.A....Singh L. (2004)
    34. Structure and polymorphisms of human aryl hydrocarbon receptor repressor (AhRR) gene in a French population: relationship with CYP1A1 inducibility and lung cancer. (PubMed id 12777964)1, 4, 9 Cauchi S....Massaad-Massade L. (2003)
    35. [Association between gene mutation of cytochrome P450 1A1 in exon 7 A4889G locus and susceptibility to endometriosis] (PubMed id 12903034)1, 4, 9 Peng D.X....Lin J.M. (2003)
    36. Studies on CYP1A1, CYP1B1 and CYP3A4 gene polymorphis ms in breast cancer patients. (PubMed id 20088394)1, 4, 9 Ociepa-Zawal M....Trzeciak W.H. (2009)
    37. Polymorphisms of Metabolizing Enzymes and Susceptibility to Ethmoid Intestinal-type Adenocarcinoma in Professionally Exposed Patients. (PubMed id 19412423)1, 4, 9 Pastore E....Pilotti S. (2009)
    38. Polymorphisms of GSTM1 and CYP1A1 genes and their genetic susceptibility to prostate cancer in Chinese men. (PubMed id 18304461)1, 4, 9 Li M....Na Y.Q. (2008)
    39. Lack of association among polymorphic xenobiotic-metabolizing enzyme genotypes and the occurrence and progression of oral carcinoma in a Brazilian population. (PubMed id 18507050)1, 4, 9 Losi-Guembarovski R....Ribeiro E.M. (2008)
    40. Maternal cigarette smoking, metabolic gene polymorphisms, and preterm delivery: new insights on GxE interactions and pathogenic pathways. (PubMed id 18320229)1, 4, 9 Tsai H.J....Wang X. (2008)
    41. [Polymorphisms of GSTM1, GSTT1 and CYP1A1 genes in mothers and neonates related to susceptibility to preterm delivery] (PubMed id 18589596)1, 4, 9 Zhang al . (2008)
    42. Polymorphisms in xenobiotic-metabolizing genes and the risk of chronic lymphocytic leukemia and non-Hodgkin's lymphoma in adult Russian patients. (PubMed id 18061941)1, 4, 9 Gra O.A....Nasedkina T.V. (2008)
    43. CYP1A1 and CYP1B1 genetic polymorphisms, smoking and breast cancer risk in a Finnish Caucasian population. (PubMed id 17063266)1, 4, 9 Sillanpaa P....Hirvonen A. (2007)
    44. Concurrent expression of aryl hydrocarbon receptor and CYP1A1 but not CYP1A1 MspI polymorphism is correlated with gastric cancers raised in Dalian, China. (PubMed id 16337337)1, 4, 9 Ma J.X....Liu J. (2006)
    45. Potential differences in breast cancer risk factors based on CYP1A1 MspI and African-American-specific genotypes. (PubMed id 16599372)1, 4, 9 Zhu K....Williams S.M. (2006)
    46. Germline genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes in Indian cervical cancer: associations with tumor progression, age and human papillomavirus infection. (PubMed id 16360200)1, 4, 9 Joseph T....Pillai M.R. (2006)
    47. Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus. (PubMed id 15643613)1, 2, 9 Jiang Z.... Nebert D.W. (2005)
    48. Effects of dietary intake and genetic factors on hypermethylation of the hMLH1 gene promoter in gastric cancer. (PubMed id 15991278)1, 4, 9 Nan H.M....Kim H. (2005)
    49. Cytochrome p4501A1 gene variants as susceptibility marker for prostate cancer. (PubMed id 17192049)1, 4, 9 Vijayalakshmi K....Paul S.F. (2005)
    50. GSTM1, GSTT1 and CYP1A1 detoxification gene polymorphisms and their relationship with advanced stages of endometriosis in South Indian women. (PubMed id 15861041)1, 4, 9 Babu K.A....Shivaji S. (2005)
    51. CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell carcinoma. (PubMed id 15914211)1, 4, 9 Gajecka M....Szyfter K. (2005)
    52. CYP1A1 and CYP1B1 genotypes, haplotypes, and TCDD-induced gene expression in subjects from Seveso, Italy. (PubMed id 15596250)1, 4, 9 Landi M.T....Bell D.A. (2005)
    53. Cytochrome P450 1A1 polymorphism and childhood leukemia: an analysis of matched pairs case-control genotype data. (PubMed id 15298960)1, 4, 9 Selvin S. (2004)
    54. An investigation of mammographic density and gene variants in healthy women. (PubMed id 15382051)1, 4, 9 Maskarinec G....Le Marchand L. (2004)
    55. [Allelic distribution of the CYP1A1 in lung cancer patients, middle-aged tissue donors and in elderly people without cancer] (PubMed id 15176217)1, 4, 9 Belogubova E.V....Imianitov E.N. (2004)
    56. Genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes and lung cancer risk. (PubMed id 14534704)1, 4, 9 Dialyna I.A....Spandidos D.A. (2003)
    57. Positive correlation between single or combined genotypes of CYP1A1 and GSTM1 in relation to prostate cancer in Chilean people. (PubMed id 12949934)1, 4, 9 Acevedo C....Quinones Sepulveda L. (2003)
    58. Maternal cigarette smoking, metabolic gene polymorphism, and infant birth weight. (PubMed id 11779261)1, 4, 9 Wang X....Xu X. (2002)
    59. [Polymorphisms of the CYP1A1 and GSTM1 genes and their combined effects on individual susceptibility to lung cancer in a Chinese population] (PubMed id 11295132)1, 4, 9 Xue K....Wu J. (2001)
    60. Genetic polymorphisms of CYP1A1, GSTM1 and P53 genes in a unique Siberian population of Tundra Nentsi and its pharmacogenetic importance. (PubMed id 11507974)1, 4, 9 Duzhak T.G....Lyakhovich V.V. (2001)
    61. Human arylhydrocarbon receptor repressor (AHRR) gene: genomic structure and analysis of polymorphism in endometriosis. (PubMed id 11393538)1, 4, 9 Watanabe T....Inazawa J. (2001)
    62. Association of GSTT1, GSTM1 and CYP1A1 polymorphisms with susceptibility to systemic lupus erythematosus in the Chinese population. (PubMed id 20226777)1, 4, 9 Zhang J....Wan J. (2010)
    63. Negative effects of serum p,p'-DDE on sperm parameters and modification by genetic polymorphisms. (PubMed id 19303595)1, 4, 9 Messaros B.M....Wirth J.J. (2009)
    64. Genetic Polymorphisms in CYP1A1, CYP1B1, COMT, GSTP1 and NAT2 Genes and Association with Bladder Cancer Risk in a French Cohort. (PubMed id 19443378)1, 4, 9 Fontana L....Bernard-Gallon D.J. (2009)
    65. [Association of nasopharyngeal carcinoma risk with cy tochrome P450 CYP1A1 gene polymorphisms] (PubMed id 19954069)1, 4, 9 Xu Y.F....Jia W.H. (2009)
    66. Genetic polymorphisms associated with cigarette smoking and the risk of Graves' disease. (PubMed id 17980001)1, 4, 9 Bufalo N.E....Ward L.S. (2008)
    67. [Association between CYP1A1 gene polymorphism and intrahepatic cholestasis of pregnancy] (PubMed id 18247309)1, 4, 9 Wang X....Su P.C. (2008)
    68. Genetic polymorphisms of metabolic enzymes CYP1A1, CYP2D6, GSTM1 and GSTT1 and leukemia susceptibility. (PubMed id 18414197)1, 4, 9 Chen H.C....Cao Y.F. (2008)
    69. Evaluation of primary DNA damage, cytogenetic biomarkers and genetic polymorphisms for CYP1A1 and GSTM1 in road tunnel construction workers. (PubMed id 18800292)1, 4, 9 Villarini M....Pasquini R. (2008)
    70. Relationship between single nucleotide polymorphisms in CYP1A1 and CYP1B1 genes and the bone mineral density and serum lipid profiles in postmenopausal Japanese women taking hormone therapy. (PubMed id 18779756)1, 4, 9 Quan J....Tanaka K. (2008)
    71. Genetic polymorphisms of cytochrome P450 CYP1A1 (*2A) and microsomal epoxide hydrolase gene, interactions with tobacco-users, and susceptibility to bladder cancer: a study from North India. (PubMed id 18200441)1, 4, 9 Srivastava D.S....Mittal R.D. (2008)
    72. Protective role of CYP1A1*2A in the development of multiple myeloma. (PubMed id 18285692)1, 4, 9 Kang S.H....Lee D.S. (2008)
    73. CYP1A1, GST gene polymorphisms and risk of chronic myeloid leukemia. (PubMed id 18224491)1, 4, 9 Taspinar M....Sunguroglu A. (2008)
    74. Susceptibility to oral cancer by genetic polymorphisms at CYP1A1, GSTM1 and GSTT1 loci among Indians: tobacco exposure as a risk modulator. (PubMed id 17307803)1, 4, 9 Anantharaman D....Mahimkar M.B. (2007)
    75. Genetic polymorphisms in CYP1A1, CYP2D6, UGT1A6, UGT1A7, and SULT1A1 genes and correlation with benzene exposure in a Chinese occupational population. (PubMed id 17479406)1, 4, 9 Gu S.Y....Xia Z.L. (2007)
    76. An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors. (PubMed id 17372252)1, 4, 9 Schwartzbaum J.A....Feychting M. (2007)
    77. [Association of the MspI polymorphism of cytochrome P4501A1 gene and smoking to the susceptibility to coronary artery disease] (PubMed id 17711714)1, 4, 9 Zhang X.M....Wu K.S. (2007)
    78. GST, NAT1, CYP1A1 polymorphisms and risk of esophageal and gastric adenocarcinomas. (PubMed id 17646057)1, 4, 9 Wideroff L....Chow W.H. (2007)
    79. Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps. (PubMed id 16926176)1, 4, 9 Goode E.L....Bigler J. (2007)
    80. Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias. (PubMed id 16493615)1, 4, 9 Aydin-Sayitoglu M....Ozbek U. (2006)
    81. Estrogen-metabolizing gene polymorphisms in the assessment of female hormone-dependent cancer risk. (PubMed id 16402077)1, 4, 9 Mikhailova O.N....Krasilnikov S.E. (2006)
    82. Influence of CYP1A1, CYP2E1, GSTM3 and NAT2 genetic polymorphisms in oral cancer susceptibility: results from a case-control study in Rio de Janeiro. (PubMed id 16488179)1, 4, 9 Marques C.F....Hatagima A. (2006)
    83. CYP17, CYP1A1 and COMT polymorphisms and the risk of adenomyosis and endometriosis in Taiwanese women. (PubMed id 16527884)1, 4, 9 Juo S.H....Tsai E.M. (2006)
    84. Joint effect among p53, CYP1A1, GSTM1 polymorphism combinations and smoking on prostate cancer risk: an exploratory genotype-environment interaction study. (PubMed id 16625286)1, 4, 9 Quinones L.A....Caceres D.D. (2006)
    85. Association of polymorphisms in AhR, CYP1A1, GSTM1, and GSTT1 genes with levels of DNA damage in peripheral blood lymphocytes among coke-oven workers. (PubMed id 16985033)1, 4, 9 Chen Y....Wu T. (2006)
    86. Genetic polymorphisms in the cytochrome P450 1A1 and 2E1 genes, smoking, drinking and prostate cancer susceptibility: a case-control study in a Han nationality population in Southern China. (PubMed id 16834659)1, 4, 9 Yang J....Zhang W. (2006)
    87. Polymorphisms of CYP1A1, GSTM1, GSTT1, and prostate cancer risk in Turkish population. (PubMed id 16466991)1, 4, 9 Silig Y....Cetinkaya O. (2006)
    88. Polymorphisms in CYP1A1 and breast carcinoma risk in a population-based case-control study of Chinese women. (PubMed id 15856430)1, 4, 9 Boyapati S.M....Zheng W. (2005)
    89. The impact of genetic factors on the incidence of multiple primary tumors (MPT) of the head and neck. (PubMed id 15914277)1, 4, 9 Rydzanicz M....Szyfter K. (2005)
    90. Polychlorinated biphenyls, cytochrome P450 1A1 (CYP1A1) polymorphisms, and breast cancer risk among African American women and white women in North Carolina: a population-based case-control study. (PubMed id 15642161)1, 4, 9 Li Y....Conway K. (2005)
    91. Genetic polymorphisms in the cytochromes P-450 (1A1, 2E1), microsomal epoxide hydrolase and glutathione S-transferase M1, T1, and P1 genes, and their relationship with chronic bronchitis and relapsing pneumonia in children. (PubMed id 15928955)1, 4, 9 Korytina G.F....Victorova T.V. (2005)
    92. The role of CYP1A1 Msp1 gene polymorphisms on lung cancer development in Turkey. (PubMed id 15765281)1, 4, 9 Demir A....Dincer I. (2005)
    93. CYP1A1 variants and smoking-related lung cancer in San Francisco Bay area Latinos and African Americans. (PubMed id 15386428)1, 4, 9 Wrensch M.R....Wiencke J.K. (2005)
    94. Genetic polymorphism of CYP1A1, CYP2D6, GSTM1 and GSTT1 and susceptibility to acute lymphoblastic leukaemia in Indian children. (PubMed id 15382273)1, 4, 9 Joseph T....Radhakrishna Pillai M. (2004)
    95. [Studies of the genes related to lung cancer susceptibility in Nanjing Han population, China.] (PubMed id 15640066)1, 4, 9 Liang G.Y....Yin L.H. (2004)
    96. Polymorphisms of GSTT1 and related genes in head and neck cancer risk. (PubMed id 14724908)1, 4, 9 Evans A.J....Beer T.M. (2004)
    97. CYP1A1, GSTM1 and GSTT1 polymorphisms and lung cancer: a pooled analysis of gene-gene interactions. (PubMed id 15764294)1, 4, 9 Vineis P....Taioli E. (2004)
    98. Risk for K-ras gene mutations in smoking-induced lung cancer is associated with cytochrome P4501A1 and glutathione S-transferase micro1 polymorphisms. (PubMed id 15375499)1, 4, 9 Noda N....Shirakusa T. (2004)
    99. Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: a case-control study in Chinese population. (PubMed id 12824892)1, 4, 9 Wang J....Tokudome S. (2003)
    100. Risk modification by CYP1A1 and GSTM1 polymorphisms in the association of environmental tobacco smoke and lung cancer: a case-control study in Japanese nonsmoking women. (PubMed id 12925969)1, 4, 9 Kiyohara C....Ohno Y. (2003)
    101. CYP1A1, CYP19, and GSTM1 polymorphisms increase the risk of endometriosis. (PubMed id 12620480)1, 4, 9 Arvanitis D.A....Spandidos D.A. (2003)
    102. Meta- and pooled analyses of GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes and risk of head and neck cancer. (PubMed id 14693745)1, 4, 9 Hashibe M....Boffetta P. (2003)
    103. Characterization of MTHFR, GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes in childhood acute leukemia. (PubMed id 12827651)1, 4, 9 Balta G....Gurgey A. (2003)
    104. Pooled analysis of the CYP1A1 exon 7 polymorphism and lung cancer (United States). (PubMed id 12846365)1, 4, 9 Le Marchand L....Taioli E. (2003)
    105. Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review). (PubMed id 12883749)1, 4, 9 Xing D....Lin D. (2003)
    106. [Relationship between genetic polymorphisms of metabolizing enzymes and prostate cancer] (PubMed id 12680328)1, 4, 9 Gao J.P....Yang Y.Q. (2003)
    107. [Analysis of the polymorphic alleles of genes encoding phase 1 and phase 2 detoxication enzymes in patients with endometriosis] (PubMed id 12760253)1, 4, 9 Ivashchenko T.E....Baranov V.S. (2003)
    108. Gene polymorphisms in detoxification enzymes as susceptibility factor for head and neck cancer? (PubMed id 12748560)1, 4, 9 Gronau S....Riechelmann H. (2003)
    109. [Polymorphism of xenobiotic detoxication genes in patients with iron deficiency anemia] (PubMed id 12934333)1, 4, 9 Safuanova G.S.h. (2003)
    110. Association of DNA-protein crosslinks and breast cancer. (PubMed id 11934439)1, 4, 9 Wu F.Y....Kuo H.W. (2002)
    111. CYP1A1, GSTM1, and GSTT1 polymorphisms and breast cancer risk in Brazilian women. (PubMed id 12175533)1, 4, 9 da Fonte de Amorim L....Pinto L. (2002)
    112. Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the Japanese population. (PubMed id 11275366)1, 4, 9 Murata M....Shiraishi T. (2001)
    113. Genetic polymorphisms of CYP1A1 and GSTM1 and lung cancer risk. (PubMed id 11501853)1, 4, 9 Gsur A....Micksche M. (2001)
    114. Tumor necrosis factor alpha polymorphism associated with increased susceptibility to development of adult T-cell leukemia/lymphoma in human T-lymphotropic virus type 1 carriers. (PubMed id 11325850)1, 4, 9 Tsukasaki K....Koeffler H.P. (2001)
    115. Genetic polymorphisms of NAD(P)H quinone oxidoreductase, CYP1A1 and microsomal epoxide hydrolase and lung cancer risk in Nanjing, China. (PubMed id 11551408)1, 4, 9 Yin L....Lin P. (2001)
    116. [Genetic polymorphisms of cytochrome P450 1A1 and susceptibility of early-onset Parkinson's disease] (PubMed id 11484167)1, 4, 9 Liu P....Chen B. (2001)
    117. Genetic susceptibility to benzene and shortened gestation: evidence of gene-environment interaction. (PubMed id 11052546)1, 4, 9 Wang X....Xu X. (2000)
    118. Relation between inducibility of CYP1A1, GSTM1 and lung cancer in a French population. (PubMed id 11037803)1, 4, 9 Stucker I....Hemon D. (2000)
    119. Genetic association study of CYP1A1 polymorphisms ide ntifies risk haplotypes in nonsmall cell lung cancer. (PubMed id 19608585)1, 4, 9 Wright C.M....Fong K.M. (2010)
    120. CYP1A1 m1 and m2 polymorphisms: genetic susceptibilit y to lung cancer. (PubMed id 20054510)1, 4, 9 Mota P....Regateiro F. (2010)
    121. Inhibition of procarcinogen-bioactivating human CYP1A 1, CYP1A2 and CYP1B1 enzymes by melatonin. (PubMed id 19919601)6, 7, 9 Chang T.K....Yeung E.Y. (2010)
    122. [Analysis of genetic predisposition to pulmonary tube rculosis in native Russians] (PubMed id 20297661)1, 4, 9 Gra O.A....Litvinov V.I. (2010)
    123. Polymorphisms in genes of the steroid hormone biosynt hesis and metabolism pathways and endometrial cancer risk. (PubMed id 20381444)1, 4, 9 Ashton K.A....Scott R.J. (2010)
    124. Lack of an association between CYP1A1 gene Ile462Val polymorphism and polycystic ovary syndrome in Chinese. (PubMed id 19507064)1, 4, 9 Wang B....Ma X. (2009)
    125. Association of CYP1A1*2 polymorphisms with breast cancer risk: a case control study. (PubMed id 19346634)1, 4, 9 Surekha D....Vishnupriya S. (2009)
    126. CYP1A1 polymorphisms and risk of prostate cancer: a m eta-analysis. (PubMed id 19472123)1, 4, 9 Shaik A.P....Das P. (2009)
    127. Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women. (PubMed id 19415745)1, 4, 9 Sangrajrang S....Yoshida T. (2009)
    128. Prevalence of CYP1A1 and GST polymorphisms in the pop ulation of northeastern India and susceptibility of oral cancer. (PubMed id 19718946)1, 4, 9 Chatterjee S....Talukder G. (2009)
    129. Single and multigenic analysis of the association bet ween variants in 12 steroid hormone metabolism genes and risk of prostate cance r. (PubMed id 19505920)1, 4, 9 Beuten J....Leach R.J. (2009)
    130. CYP1A1 genotype modifies the impact of smoking on eff ectiveness of HAART among women. (PubMed id 19537956)1, 4, 9 Feldman D.N....Burk R. (2009)
    131. Genetic polymorphisms in estrogen metabolism and breast cancer risk in case-control studies in Japanese, Japanese Brazilians and non-Japanese Brazilians. (PubMed id 19229255)1, 4, 9 Shimada N....Tsugane S. (2009)
    132. Role of xenobiotic-metabolizing enzyme gene polymorph isms and interactions with environmental factors in susceptibility to gastric c ancer in Kashmir Valley. (PubMed id 19521675)1, 4, 9 Malik M.A....Mittal B. (2009)
    133. Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women. (PubMed id 19424794)1, 4, 9 (2009)
    134. Interaction between cytochrome P450 1A2 genetic polym orphism and cigarette smoking on the risk of hepatocellular carcinoma in a Japa nese population. (PubMed id 19643819)1, 4, 9 Imaizumi T....Tanaka K. (2009)
    135. CYP 450 polymorphisms as risk factors for early onset lung cancer: gender specific differences. (PubMed id 19414505)1, 4, 9 Timofeeva M....Wichmann H.E. (2009)
    136. Effect of combined genetic polymorphisms on lung canc er risk in northern Thai women. (PubMed id 19963114)1, 4, 9 Klinchid J....Cressey R. (2009)
    137. [The effect of polymorphism of genes of xenobiotics d etoxication on the frequencies of spontaneous and induced chromosome aberration s in human lymphocytes] (PubMed id 19947517)1, 4, 9 Sal'nikova L.E....Rubanovich A.V. (2009)
    138. [Association of xenobiotic-metabolizing gene polymorp hisms with childhood atopic diseases in Russian patients from the Republic of B ashkortostan] (PubMed id 20088379)1, 4, 9 Fedorova I.u.I.u....Khusnutdinova E.K. (2009)
    139. Polymorphisms of cytochrome P450 1A1, cigarette smoki ng and risk of coronary artery disease. (PubMed id 19563927)1, 4, 9 Yeh C.C....Chu H.Y. (2009)
    140. Evaluation of genetic damage in a Brazilian population occupationally exposed to pesticides and its correlation with polymorphisms in metabolizing genes. (PubMed id 18550589)1, 4, 9 da Silva J....Erdtmann B. (2008)
    141. Interaction of cytochrome P4501A1 genotypes with other risk factors and susceptibility to lung cancer. (PubMed id 18082227)1, 4, 9 Shah P.P....Parmar D. (2008)
    142. Genetic polymorphisms in oestrogen metabolic pathway and breast cancer: a positive association with combined CYP/GST genotypes. (PubMed id 18618215)1, 4, 9 Torresan C....Ribeiro E.M. (2008)
    143. Polymorphisms in phase I and phase II metabolism genes and risk of chronic benzene poisoning in a Chinese occupational population. (PubMed id 18784359)1, 4, 9 Sun P....Xia Z.L. (2008)
    144. Association between genetic polymorphisms and ovarian cancer risk. (PubMed id 19031960)1, 4, 9 Delort L....Bernard-Gallon D.J. (2008)
    145. Lung cancer risk in north Indian population: role of genetic polymorphisms and smoking. (PubMed id 19009239)1, 4, 9 Kumar M....Goel S.K. (2008)
    146. GSTM1 polymorphism along with PM10 exposure contributes to the risk of preterm delivery. (PubMed id 18706519)1, 4, 9 Suh Y.J....Hong Y.C. (2008)
    147. CYP1A1, GSTM1, and GSTT1 polymorphisms, smoking, and lung cancer risk in a pooled analysis among Asian populations. (PubMed id 18463401)1, 4, 9 Lee K.M....Taioli E. (2008)
    148. Combined effect of GSTM1, GSTT1 and GSTP1 polymorphisms on histological subtypes of lung cancer. (PubMed id 18415801)1, 4, 9 Sobti R.C....Raimondi S. (2008)
    149. Oxidative stress-related gene interactions with preterm delivery in Korean women. (PubMed id 18241825)1, 4, 9 Suh Y.J....Ha E.H. (2008)
    150. CYP1B1, CYP1A1, MPO, and GSTP1 polymorphisms and lung cancer risk in never-smoking Korean women. (PubMed id 17980933)1, 4, 9 Yoon K.A....Lee J.S. (2008)
    151. Association of CYP1A1 and glutathione S-transferase polymorphisms with male factor infertility. (PubMed id 18774560)1, 4, 9 Aydos S.E....Aydos K. (2008)
    152. Cigarette smoking and glutathione S-transferase M1 polymorphism associated with risk for uterine cervical cancer. (PubMed id 19012698)1, 4, 9 Nishino K....Tanaka K. (2008)
    153. Relevance of glutathione S-transferase M1 and cytochrome P450 1A1 genetic polymorphisms to the development of head and neck cancers. (PubMed id 18590468)1, 4, 9 Reszka E....Wasowicz W. (2008)
    154. Polymorphisms of drug-metabolizing enzymes CYP1A1, GSTT and GSTP contribute to the development of diffuse large B-cell lymphoma risk in the Saudi Arabian population. (PubMed id 18203021)1, 4, 9 Al-Dayel F....Al-Kuraya K. (2008)
    155. Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome. (PubMed id 18768509)1, 4, 9 Pande M....Frazier M.L. (2008)
    156. Comparative analysis of SNP in estrogen-metabolizing enzymes for ovarian, endometrial, and breast cancers in Novosibirsk, Russia. (PubMed id 18497059)1, 4, 9 Gulyaeva L.F....Pechkovsky E.V. (2008)
    157. CYP1A1 and GSTM1 polymorphisms and lung cancer risk in Chinese populations: a meta-analysis. (PubMed id 17900751)1, 4, 9 Shi X....Wang Z. (2008)
    158. Polymorphism of CYP1A1*2C, GSTM1*0, and GSTT1*0 in a Mexican Mestizo population: a similitude analysis. (PubMed id 19317600)1, 4, 9 PAcrez-Morales R....Rubio J. (2008)
    159. Genetic polymorphisms of carcinogen metabolizing enzymes are associated with oral leukoplakia development and p53 overexpression. (PubMed id 18507060)1, 4, 9 Duarte E.C....Gomez R.S. (2008)
    160. [Using MSR model to analyze the impact of gene-gene interaction with related to the genetic polymorphism of metabolism enzymes on the risk of breast cancer] (PubMed id 19024313)1, 4, 9 Li J.Y....Li S.F. (2008)
    161. Breast cancer: a candidate gene approach across the estrogen metabolic pathway. (PubMed id 17588204)1, 4, 9 Justenhoven C....Brauch H. (2008)
    162. CYP1A1 and CYP1B1 genetic polymorphisms and uterine leiomyoma risk in Chinese women. (PubMed id 18763031)1, 4, 9 Ye Y....Hou Y.P. (2008)
    163. CYP1A1 gene polymorphism and polycystic ovary syndrome. (PubMed id 18339256)1, 4, 9 Esinler I....Tuncbilek E. (2008)
    164. Lack of association between the functional polymorphisms in the estrogen-metabolizing genes and risk for hepatocellular carcinoma. (PubMed id 19064581)1, 4, 9 Yuan X....He F. (2008)
    165. Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms. (PubMed id 18593984)1, 4, 9 Bell D.W....Haber D.A. (2008)
    166. Variant in sex hormone-binding globulin gene and the risk of prostate cancer. (PubMed id 17220347)1, 4, 9 Berndt S.I....Hayes R.B. (2007)
    167. Cytochrome P450 1A1, cigarette smoking, and risk of endometrial cancer (United States). (PubMed id 17717632)1, 4, 9 McGrath M....De Vivo I. (2007)
    168. Cytochrome P4501A1 and microsomal epoxide hydrolase gene polymorphisms: gene-environment interaction and risk of prostate cancer. (PubMed id 17919073)1, 4, 9 Mittal R.D. and Srivastava D.L. (2007)
    169. Cytochrome P450 1A1 (CYP1A1) polymorphisms and breast cancer risk in Korean women. (PubMed id 17603290)1, 4, 9 Shin A....Yoo K.Y. (2007)
    170. Combined effects of genetic polymorphisms in six selected genes on lung cancer susceptibility. (PubMed id 17428572)1, 4, 9 Yang M....Lee J.S. (2007)
    171. Evaluation of genetic variations in the androgen and estrogen metabolic pathways as risk factors for sporadic and familial prostate cancer. (PubMed id 17507624)1, 4, 9 Cunningham J.M....Thibodeau S.N. (2007)
    172. Association of CYP1B1 germ line mutations with hepatocyte nuclear factor 1alpha-mutated hepatocellular adenoma. (PubMed id 17363580)1, 4, 9 Jeannot E....Zucman-Rossi J. (2007)
    173. Association of CYP1A1, CYP1A2, GSTM1 and NAT2 gene polymorphisms with colorectal cancer and smoking. (PubMed id 18159984)1, 4, 9 Yoshida K....Takahashi J. (2007)
    174. A study on the association of cytochrome-P450 1A1 polymorphism and breast cancer risk in north Indian women. (PubMed id 16807674)1, 4, 9 Singh V....Singh M.P. (2007)
    175. Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants. (PubMed id 17160896)1, 4, 9 Shi M....Murray J.C. (2007)
    176. NAT2 and CYP1A2 polymorphisms and lung cancer risk in relation to smoking status. (PubMed id 17477782)1, 4, 9 Osawa Y....Takahashi J. (2007)
    177. Association of CYP1A1 polymorphisms with breast cancer in North Indian women. (PubMed id 18351133)1, 4, 9 Singh N....Rath S.K. (2007)
    178. Association between polymorphisms of biotransformation and DNA-repair genes and risk of colorectal cancer in Taiwan. (PubMed id 17191090)1, 4, 9 Yeh C.C....Hsieh L.L. (2007)
    179. Polymorphisms in CYP1A1 gene are associated with male infertility in a Chinese population. (PubMed id 17651397)1, 4, 9 Lu N....Wang X. (2007)
    180. Susceptibility to pre-eclampsia is associated with multiple genetic polymorphisms in maternal biotransformation enzymes. (PubMed id 17167268)1, 4, 9 Zusterzeel P.L....Steegers E.A. (2007)
    181. Urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) and genetic polymorphisms in breast cancer patients. (PubMed id 17512776)1, 4, 9 Kuo H.W....Chen D.J. (2007)
    182. Genotyping of eight polymorphic genes encoding drug-metabolizing enzymes and transporters using a customized oligonucleotide array. (PubMed id 17113562)1, 4, 9 Lu Y....Yeoh A.E. (2007)
    183. Primary DNA damage and genetic polymorphisms for CYP1A1, EPHX and GSTM1 in workers at a graphite electrode manufacturing plant. (PubMed id 17908297)1, 4, 9 Moretti M....Pasquini R. (2007)
    184. The risk of developing cervical cancer in Mexican women is associated to CYP1A1 MspI polymorphism. (PubMed id 17512722)1, 4, 9 Juarez-Cedillo T....Vargas-Alarcon G. (2007)
    185. Pairwise combinations of estrogen metabolism genotypes in postmenopausal breast cancer etiology. (PubMed id 17372239)1, 4, 9 Rebbeck T.R....Strom B.L. (2007)
    186. Genetic polymorphisms in estrogen-metabolizing genes and breast cancer survival. (PubMed id 17429315)1, 4, 9 Long J.R....Zheng W. (2007)
    187. GSTM1, GSTT1 and CYP1A1 detoxification gene polymorphisms and susceptibility to smoking-related coronary artery disease: a case-only study. (PubMed id 17408703)1, 4, 9 Manfredi S....Andreassi M.G. (2007)
    188. Glutathione S-transferase and CYP1A1 gene polymorphisms and non-melanoma skin cancer risk in Italian transplanted patients. (PubMed id 17083362)1, 4, 9 Lira M.G....Tessari G. (2006)
    189. Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: effects on DNA damage. (PubMed id 16043197)1, 4, 9 Naccarati A....Vodicka P. (2006)
    190. Variation in genes relevant to aromatic hydrocarbon metabolism and the risk of adult brain tumors. (PubMed id 16598069)1, 4, 9 De Roos A.J....Inskip P.D. (2006)
    191. Genetic polymorphism of metabolic enzymes modifies the risk of chronic solvent-induced encephalopathy. (PubMed id 17022435)1, 4, 9 Kezic S....Verberk M.M. (2006)
    192. Association between metabolic gene polymorphisms and susceptibility to peripheral nerve damage in workers exposed to n-hexane: a preliminary study. (PubMed id 16484137)1, 4, 9 Zhang Y....Zheng Y. (2006)
    193. GSTM1 and CYP1A1 polymorphisms, tobacco, air pollution, and lung cancer: a study in rural Thailand. (PubMed id 16614107)1, 4, 9 Pisani P....Bishop D.T. (2006)
    194. CYP1A1 gene polymorphism and risk of endometrial hyperplasia and endometrial carcinoma. (PubMed id 16803538)1, 4, 9 Esinler I....Ayhan A. (2006)
    195. Genetic polymorphisms in CYP1A1 and GSTM1 predispose humans to PCBs/PCDFs-induced skin lesions. (PubMed id 16580705)1, 4, 9 Tsai P.C....Guo Y.L. (2006)
    196. Association of DNA repair and steroid metabolism gene polymorphisms with clinical late toxicity in patients treated with conformal radiotherapy for prostate cancer. (PubMed id 16638864)1, 4, 9 Damaraju S....Parliament M. (2006)
    197. Influence of polymorphisms in xenobiotic-metabolizing genes and DNA-repair genes on diepoxybutane-induced SCE frequency. (PubMed id 17078101)1, 4, 9 Laczmanska I....Sasiadek M.M. (2006)
    198. Combined CYP1A1/GSTM1 at-risk genotypes are overrepresented in squamous cell lung carcinoma patients but underrepresented in elderly tumor-free subjects. (PubMed id 16416283)1, 4, 9 Belogubova E.V....Imyanitov E.N. (2006)
    199. Metabolic gene variants and risk of non-Hodgkin's lymphoma. (PubMed id 16985026)1, 4, 9 De Roos A.J....Severson R.K. (2006)
    200. Oxidative stress-related gene polymorphism and the risk of preeclampsia. (PubMed id 15734083)1, 4, 9 Kim Y.J....Pang M.G. (2005)
    201. [Association of metabolic and DNA repair enzyme gene polymorphisms and DNA damage in coke-oven workers] (PubMed id 15938845)1, 4, 9 Cheng J....Zheng Y.X. (2005)
    202. Maternal genetic polymorphisms in CYP1A1, GSTM1 and GSTT1 and the risk of hypospadias. (PubMed id 15579657)1, 4, 9 Kurahashi N....Kishi R. (2005)
    203. Cytochrome gene polymorphisms, serum estrogens, and hot flushes in midlife women. (PubMed id 16319265)1, 4, 9 Visvanathan K....Flaws J.A. (2005)
    204. CYP1A1 alleles in female genital cancers in the Polish population. (PubMed id 15653213)1, 4, 9 Seremak-Mrozikiewicz A....Mrozikiewicz P.M. (2005)
    205. Role of xenobiotic metabolizing gene polymorphisms in breast cancer susceptibility and treatment outcome. (PubMed id 15725614)1, 4, 9 Chacko P....Pillai M.R. (2005)
    206. Estrogen metabolism-related genes and breast cancer risk: the multiethnic cohort study. (PubMed id 16103451)1, 4, 9 Le Marchand L....Wilkens L.R. (2005)
    207. An interethnic comparison of polymorphisms of the genes encoding drug-metabolizing enzymes and drug transporters: experience in Singapore. (PubMed id 15931768)1, 4, 9 Chowbay B....Lee E.J. (2005)
    208. Cytochrome P-450 1A1 gene polymorphisms and risk of breast cancer: a HuGE review. (PubMed id 15870154)1, 4, 9 Masson L.F....Little J. (2005)
    209. Childhood leukaemia, polymorphisms of metabolism enzyme genes, and interactions with maternal tobacco, coffee and alcohol consumption during pregnancy. (PubMed id 16284498)1, 4, 9 Clavel J....Loriot M.A. (2005)
    210. Cytochrome P4501A1 genetic polymorphisms and breast cancer risk in Nigerian women. (PubMed id 16254684)1, 4, 9 Okobia M....Kuller L. (2005)
    211. [Polymorphism of metabolic gene and genetic susceptibility to prostate cancer] (PubMed id 16318816)1, 4, 9 Guan T.Y....Na Y.Q. (2005)
    212. CYP1A1 and GSTM1 genetic polymorphisms in lung cancer populations exposed to arsenic in drinking water. (PubMed id 16012082)1, 4, 9 Adonis M....Gil L. (2005)
    213. CYP1A1 and GSTM1 polymorphisms in relation to lung cancer risk in Chinese women. (PubMed id 15363546)1, 4, 9 Yang X.R....Caporaso N.E. (2004)
    214. [Effect of genetic polymorphisms of microsomal epoxide hydrolase on urinary 1-hydroxypyrene levels in coke oven workers] (PubMed id 15355699)1, 4, 9 Leng S.G....He F.S. (2004)
    215. Cytochrome P4501A1 polymorphism is associated with susceptibility to acute lymphoblastic leukemia in adult Mexican patients. (PubMed id 15528152)1, 4, 9 Gallegos-Arreola M.P....Zuniga-Gonzalez G.M. (2004)
    216. Genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia. (PubMed id 14991750)1, 4, 9 Canalle R....Takahashi C.S. (2004)
    217. Serum polychlorinated biphenyls, cytochrome P-450 1A1 polymorphisms, and risk of breast cancer in Connecticut women. (PubMed id 15583370)1, 4, 9 Zhang Y....Zheng T. (2004)
    218. [Polymorphisms in detoxification genes CYP1A1, CYP2E1, GSTT1 and GSTM1 in gastric cancer susceptibility] (PubMed id 17361553)1, 4, 9 Gonzalez A....Sierra R. (2004)
    219. Xenobiotic gene polymorphisms and susceptibility to multiple myeloma. (PubMed id 15136237)1, 4, 9 Lincz L.F....Spencer A. (2004)
    220. Polymorphisms of CYP1A1 and glutathione S-transferase and susceptibility to adult acute myeloid leukemia. (PubMed id 15194533)1, 4, 9 D'Alo F....Leone G. (2004)
    221. Association of CYP1A1 gene polymorphism with recurrent pregnancy loss in the South Indian population. (PubMed id 15333597)1, 4, 9 Suryanarayana V....Singh L. (2004)
    222. The effects of diet on DNA bulky adduct levels are strongly modified by GSTM1 genotype: a study on 634 subjects. (PubMed id 14656945)1, 4, 9 Palli D....Garte S. (2004)
    223. A polymorphism in the CYP17 gene and intrauterine fetal growth restriction. (PubMed id 14665706)1, 4, 9 Yamada H....Minakami H. (2004)
    224. [Association of cytochrome P450 gene MSP1 polymorphism and risk of preterm.] (PubMed id 15605089)1, 4, 9 Jin Y....Wang L.H. (2004)
    225. Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer. (PubMed id 15352038)1, 4, 9 Turner F....Barrett J.H. (2004)
    226. Polymorphic variation of Cyp1A1 is associated with the risk of gastric cardia cancer: a prospective case-cohort study of cytochrome P-450 1A1 and GST enzymes. (PubMed id 15801491)1, 4, 9 Roth M.J....Qiao Y.L. (2004)
    227. [A study on the inherited susceptibility of chromosomal damage in peripheral blood lymphocytes among coke oven workers] (PubMed id 15061915)1, 4, 9 Leng S.G....He F.S. (2004)
    228. Benzo(a)pyrene diolepoxide (BPDE)-DNA adduct levels in leukocytes of smokers in relation to polymorphism of CYP1A1, GSTM1, GSTP1, GSTT1, and mEH. (PubMed id 15298956)1, 4, 9 Lodovici M....Dolara P. (2004)
    229. CYP1A1 and XRCC1 gene polymorphisms in SCC of the larynx. (PubMed id 14639127)1, 4, 9 Varzim G....Lopes C. (2003)
    230. Effects of dietary habits and CYP1A1 polymorphisms on blood dioxin concentrations in Japanese men. (PubMed id 12729704)1, 4, 9 Tsuchiya Y....Yamamoto M. (2003)
    231. CYP enzyme polymorphisms and susceptibility to HCV-related chronic liver disease and liver cancer. (PubMed id 12569554)1, 4, 9 Silvestri L....Silini E.M. (2003)
    232. Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population. (PubMed id 12879168)1, 4, 9 Gaikovitch E.A....Roots I. (2003)
    233. Genetic polymorphisms in biotransformation enzymes in Crohn's disease: association with microsomal epoxide hydrolase. (PubMed id 12631667)1, 4, 9 de Jong D.J....Naber T.H. (2003)
    234. Polymorphisms in the CYP1A1 gene are associated with prostate cancer risk. (PubMed id 12845676)1, 4, 9 Chang B.L....Xu J. (2003)
    235. CYP1A1*2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated with FLT3 internal tandem duplication. (PubMed id 12468438)1, 4, 9 Bowen D.T....Morgan G.J. (2003)
    236. Effects of genetic polymorphisms in metabolic enzymes on the relationships between 8-hydroxydeoxyguanosine levels in human leukocytes and urinary 1-hydroxypyrene and 2-naphthol concentrations. (PubMed id 14646291)1, 4, 9 Kim Y.D....Kim H. (2003)
    237. [First results on the influence of polymorphisms at glutathione S-transferase, cytochrome P450, and tumor necrosis factor gene loci on the development of multiple head and neck cancer] (PubMed id 12548461)1, 4, 9 Matthias C....Strange R.C. (2003)
    238. Estrogen-metabolizing gene polymorphisms, but not estrogen receptor-alpha gene polymorphisms, are associated with the onset of menarche in healthy postmenopausal Japanese women. (PubMed id 12574216)1, 4, 9 Gorai I....Hirahara F. (2003)
    239. Cytochrome P450 and manganese superoxide dismutase genes polymorphisms in systemic lupus erythematosus. (PubMed id 14611903)1, 4, 9 Yen J.H....Liu H.W. (2003)
    240. Polymorphism in CYP1A1 and CYP2E1 genes and susceptibility to leukoplakia in Indian tobacco users. (PubMed id 12767509)1, 4, 9 Sikdar N....Roy B. (2003)
    241. Interaction between CYP1A1 polymorphic variants and dietary exposures influencing ovarian cancer risk. (PubMed id 12646505)1, 4, 9 Terry K.L....Cramer D.W. (2003)
    242. Analysis of polymorphic patterns in candidate genes in Israeli patients with prostate cancer. (PubMed id 14719475)1, 4, 9 Figer A....Friedman E. (2003)
    243. Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples. (PubMed id 14634838)1, 4, 9 Yoshimura K....Tsugane S. (2003)
    244. CYP1A1, GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma: study of population from a high- incidence area in north China. (PubMed id 12854128)1, 4, 9 Wang L.D....Li J.X. (2003)
    245. Polymorphisms of CYP1a1, CYP2e1, GSTM1, GSTT1, and TP53 genes in Amerindians. (PubMed id 12365037)1, 4, 9 Gaspar P.A....Weimer T.A. (2002)
    246. Polymorphism of metabolic genes and susceptibility to occupational chronic manganism. (PubMed id 12171760)1, 4, 9 Zheng Y.X....He F.S. (2002)
    247. [Genetic polymorphism of cytochrome P4501A1 and susceptibility to laryngeal carcinoma] (PubMed id 12772461)1, 4, 9 Lei D....Liu D. (2002)
    248. Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas. (PubMed id 12397416)1, 4, 9 Soucek P....Gut I. (2002)
    249. Genetic polymorphisms of cytochrome P4501A1 and oesophageal squamous-cell carcinoma in Taiwan. (PubMed id 12189551)1, 4, 9 Wu M.T....Kao E.L. (2002)
    250. A population-based, case-control study of polymorphisms in carcinogen-metabolizing genes, smoking, and pancreatic adenocarcinoma risk. (PubMed id 11854392)1, 4, 9 Duell E.J....Kelsey K.T. (2002)
    251. Polymorphisms of GSTP1 and related genes and prostate cancer risk. (PubMed id 15195126)1, 4, 9 Beer T.M....Henner W.D. (2002)
    252. Susceptibility factors and DNA adducts in peripheral blood mononuclear cells of aluminium smelter workers exposed to polycyclic aromatic hydrocarbons. (PubMed id 11967624)1, 4, 9 Tuominen R....Rannug A. (2002)
    253. Genetic polymorphism of cytochrome P4501A1 and susceptibility to oral squamous cell carcinoma and oral precancer lesions associated with smoking/betel use. (PubMed id 12269988)1, 4, 9 Kao S.Y....Liu T.Y. (2002)
    254. Effect of CYP1A1 MspI polymorphism on cigarette smoking related coronary artery disease and diabetes. (PubMed id 11996959)1, 4, 9 Wang X.L....Wilcken D.E. (2002)
    255. Genetic polymorphisms in the cytochrome P450 1A1, glutathione S-transferase M1 and T1, and susceptibility to colon cancer. (PubMed id 12210502)1, 4, 9 Ye Z. and Parry J.M. (2002)
    256. Lack of association between CYP1A1 polymorphism and Parkinson's disease in a Chinese population. (PubMed id 11793160)1, 4, 9 Chan D.K....Kay R. (2002)
    257. A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. (PubMed id 12419832)1, 4, 9 Sachse C....Wolf C.R. (2002)
    258. A population-based study of the Arg399Gln polymorphism in X-ray repair cross- complementing group 1 (XRCC1) and risk of pancreatic adenocarcinoma. (PubMed id 12183419)1, 4, 9 Duell E.J....Kelsey K.T. (2002)
    259. The effect of relevant genotypes on PAH exposure-related biomarkers. (PubMed id 11859435)1, 4, 9 Kuljukka-Rabb T....Peltonen K. (2002)
    260. Contribution of the NQO1 and GSTT1 polymorphisms to lung adenocarcinoma susceptibility. (PubMed id 12163326)1, 4, 9 Sunaga N....Yokota J. (2002)
    261. DNA adducts, genetic polymorphisms, and K-ras mutation in human pancreatic cancer. (PubMed id 11719088)1, 4, 9 Li D....Abbruzzese J.L. (2002)
    262. Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes, DNA repair enzymes, and response to treatment of childhood acute lymphoblastic leukemia. (PubMed id 11895912)1, 4, 9 Krajinovic M....Sinnett D. (2002)
    263. Association between xenobiotic gene polymorphisms and non-Hodgkin's lymphoma risk. (PubMed id 12139735)1, 4, 9 Kerridge I....Spencer A. (2002)
    264. Molecular epidemiology of preterm delivery: methodology and challenges. (PubMed id 11520401)1, 4, 9 Wang X....Xu X. (2001)
    265. Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas. (PubMed id 11406608)1, 4, 9 Sarmanova J....Soucek P. (2001)
    266. Linkage and association studies of the relationship between endometriosis and genes encoding the detoxification enzymes GSTM1, GSTT1 and CYP1A1. (PubMed id 11675474)1, 4, 9 Hadfield R.M....Kennedy S.H. (2001)
    267. Genetic susceptibility to breast cancer in French-Canadians: role of carcinogen-metabolizing enzymes and gene-environment interactions. (PubMed id 11291049)1, 4, 9 Krajinovic M....Sinnett D. (2001)
    268. Association between genetic polymorphisms and biomarkers in styrene-exposed workers. (PubMed id 11535253)1, 4, 9 Vodicka P....Hemminki K. (2001)
    269. Metabolic genotypes and risk for colorectal cancer. (PubMed id 11422615)1, 4, 9 Butler W.J....Roberts-Thomson I.C. (2001)
    270. Metabolic gene polymorphism frequencies in control populations. (PubMed id 11751440)1, 4, 9 Garte S....Taioli E. (2001)
    271. Genetic polymorphism of CYP1A1, GSTM1 and GSTT1 genes in Indian oral cancer. (PubMed id 11564581)1, 4, 9 Sreelekha T.T....Pillai M.R. (2001)
    272. CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people. (PubMed id 11675150)1, 4, 9 Quinones L....Gil L. (2001)
    273. [Association between cytochrome P-450 enzyme gene polymorphisms and Parkinson's disease] (PubMed id 11798822)1, 4, 9 Wang J....Chen B. (2000)
    274. Poor metabolizers at the cytochrome P450 2D6 and 2C19 loci are at increased risk of developing adult acute leukaemia. (PubMed id 11037802)1, 4, 9 Roddam P.L....Morgan G.J. (2000)
    275. [Cytochrome P450IA1 and the genetic susceptibility to esophageal carcinoma] (PubMed id 11860900)1, 4, 9 Zhang H....Yan M. (2000)
    276. Association of CYP1A1 germ line polymorphisms with mutations of the p53 gene in lung cancer. (PubMed id 8548778)1, 4, 9 Kawajiri K....Yamamoto M. (1996)
    277. Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism. (PubMed id 23508959)1, 2 Walsh A.A.... Scott E.E. (2013)
    278. Genome-wide association analysis of coffee drinking su ggests association with CYP1A1/CYP1A2 and NRCAM. (PubMed id 21876539)1, 4 Amin N....van Duijn C.M. (2012)
    279. Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption. (PubMed id 21490707)1, 4 Cornelis M.C....Caporaso N.E. (2011)
    280. Genetic polymorphisms of metabolic enzymes-CYP1A1, CY P2D6, GSTM1, and GSTT1, and gastric carcinoma susceptibility. (PubMed id 20878561)1, 4 Luo Y.P....Zhang D.Z. (2011)
    281. Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption. (PubMed id 21357676)1, 4 Sulem P....Stefansson K. (2011)
    282. Lack of significant association between CYP1A1 T3801C polymorphism and breast cancer risk: a meta-analysis involving 25,087 subjects . (PubMed id 20052535)1, 4 Yao L....Yu L. (2010)
    283. The role of MSP I CYP1A1 gene polymorphism in the dev elopment of uterine fibroids. (PubMed id 20579990)1, 4 BarALo M.A....Castro R.d.e. .A. (2010)
    284. Prevalence of the MspI and Ile462Val SNPs of cytochro me P-450 1A1 in hidradenitis suppurativa. (PubMed id 20584197)1, 4 Lukowsky A....Schneider-Burrus S. (2010)
    285. Oxidative damage to biological macromolecules in Prag ue bus drivers and garagemen: impact of air pollution and genetic polymorphisms . (PubMed id 20723587)1, 4 Bagryantseva Y....Sram R.J. (2010)
    286. Physiogenomic analysis of statin-treated patients: do main-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)1, 4 RuaA+o G....Wu A.H. (2010)
    287. Combined effect of smoking and polymorphisms in tobac co carcinogen-metabolizing enzymes CYP1A1 and GSTM1 on the head and neck cancer risk in North Indians. (PubMed id 20491576)1, 4 Sharma R....Khullar M. (2010)
    288. [The relationship between genotypes and frequencies o f chromosome aberrations in human lymphocytes under irradiation in vivo and in vitro]. (PubMed id 20734807)1, 4 Sal'nikova L.E....Rubanovich A.V. (2010)
    289. Genetic association of phase I and phase II detoxific ation genes with recurrent miscarriages among North Indian women. (PubMed id 19892789)1, 4 Parveen F....Agrawal S. (2010)
    290. Evidence that genetic variants of metabolic detoxicat ion and cell cycle control are not related to gallbladder cancer risk in Chilea n women. (PubMed id 20544687)1, 4 Tsuchiya Y....Yamamoto M. (2010)
    291. Review of studies on metabolic genes and cancer in po pulations of African descent. (PubMed id 20027111)1, 4 Ragin C.C....Taioli E. (2010)
    292. Gene-gene interactions of drug metabolizing enzymes a nd transporter protein in the risk of upper aerodigestive tract cancers among I ndians. (PubMed id 20554493)1, 4 Sam S.S....Chandrasekaran A. (2010)
    293. Additional candidates to conventional genes susceptib le for lung cancer and changing trend in Japan. (PubMed id 20428802)1, 4 Okazaki I....Watanabe T. (2010)
    294. Methods for detecting interactions between genetic po lymorphisms and prenatal environment exposure with a mother-child design. (PubMed id 19582785)1, 4 Wang S....Perera F.P. (2010)
    295. The GSTP1 Ile105 Val polymorphism modifies the metabo lism of toluene di-isocyanate. (PubMed id 20032816)1, 4 Broberg K.E....Rannug A. (2010)
    296. Genetic variation in the estrogen metabolic pathway a nd mammographic density as an intermediate phenotype of breast cancer. (PubMed id 20214802)1, 4 Li J....Hall P. (2010)
    297. Effect of gene-environment Interactions on mental dev elopment in African American, Dominican, and Caucasian mothers and newborns. (PubMed id 19860743)1, 4 Wang S....Perera F.P. (2010)
    298. Genetic Variation in the Bioactivation Pathway for Po lycyclic Hydrocarbons and Heterocyclic Amines in Relation to Risk of Colorectal Neoplasia. (PubMed id 21081473)1, 4 Wang H....Le Marchand L. (2010)
    299. Alcohol, tobacco and genetic susceptibility in relati on to cancers of the upper aerodigestive tract in northern Italy. (PubMed id 20437850)1, 4 Canova C....Simonato L. (2010)
    300. Interactions between cigarette smoking and selected p olymorphisms in xenobiotic metabolizing enzymes in risk for colorectal cancer: A case-only analysis. (PubMed id 20886582)1, 4 Pande M....Frazier M.L. (2010)
    301. CYP1A1 gene polymorphisms increase lung cancer risk i n a high-incidence region of Spain: a case control study. (PubMed id 20804547)1, 4 San Jose C....Gervasini G. (2010)
    302. Gene-environment interactions associated with CYP1A1 MspI and GST polymorphisms and the risk of upper aerodigestive tract cancers in an Indian population. (PubMed id 20012094)1, 4 Sam S.S....Chandrasekaran A. (2010)
    303. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    304. Genetic polymorphisms in cytochrome P450s, GSTs, NATs , alcohol consumption and risk of non-Hodgkin lymphoma. (PubMed id 20131310)1, 4 Li Y....Zhang Y. (2010)
    305. Herpesvirus type 7 infection may play an important ro le in individuals with a genetic profile of susceptibility to Graves' disease. (PubMed id 19903800)1, 4 Leite J.L....Ward L.S. (2010)
    306. CYP and GST polymorphisms and survival in advanced no n-small cell lung cancer patients. (PubMed id 20845989)1, 4 Ada A.O....Iscan M. (2010)
    307. CYP 1A1 polymorphism and organochlorine pesticides le vels in the etiology of prostate cancer. (PubMed id 20817259)1, 4 Kumar V....Banerjee B.D. (2010)
    308. Impact of CYP1A1 and COMT genotypes on breast cancer risk in Mexican women: a pilot study. (PubMed id 20878621)1, 4 Moreno-GalvA!n M....Sarti E. (2010)
    309. Increased risk for acute lymphoblastic leukemia in ch ildren with cytochrome P450A1 (CYP1A1)- and NAD(P)H:quinone oxidoreductase 1 (N QO1)-inherited gene variants. (PubMed id 20962519)1, 4 Yamaguti G.G....Lima C.S. (2010)
    310. Pharmacogenomics of maternal tobacco use: metabolic g ene polymorphisms and risk of adverse pregnancy outcomes. (PubMed id 20177288)1, 4 Aagaard-Tillery K....Wapner R.J. (2010)
    311. Genetic polymorphisms in cytochrome P450 genes are as sociated with an increased risk of squamous cell carcinoma of the larynx and hy popharynx in a Chinese population. (PubMed id 19963139)1, 4 Tai J....Han D. (2010)
    312. Hypermethylation of carcinogen metabolism genes, CYP1 A1, CYP2A13 and GSTM1 genes in head and neck cancer. (PubMed id 20846153)1, 4 Sharma R....Khullar M. (2010)
    313. CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD. (PubMed id 20080081)1, 4 Vibhuti A....Pasha M.A. (2010)
    314. The Association Between a Functional CYP1A1 Polymorph ism and Colorectal Neoplasia Risk in Post Menopausal Women. (PubMed id 20094781)1, 4 Early D.S....Armamento-Villareal R. (2010)
    315. Cigarette smoking, genetic variants in carcinogen-met abolizing enzymes, and colorectal cancer risk. (PubMed id 20937634)1, 4 Cleary S.P....Harper P. (2010)
    316. Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk. (PubMed id 20375710)1, 4 Northwood E.L....Smith G. (2010)
    317. Candidate gene association studies and risk of childh ood acute lymphoblastic leukemia: a systematic review and meta-analysis. (PubMed id 20511665)1, 4 Vijayakrishnan J. and Houlston R.S. (2010)
    318. Association of testicular germ cell tumor with polymo rphisms in estrogen receptor and steroid metabolism genes. (PubMed id 19776291)1, 4 Ferlin A....Foresta C. (2010)
    319. Association of xenobiotic metabolizing enzymes geneti c polymorphisms with esophageal cancer in Kashmir Valley and influence of envir onmental factors. (PubMed id 20661821)1, 4 Malik M.A....Mittal B. (2010)
    320. The CYP1A1 Ile462Val polymorphism and platinum resist ance of epithelial ovarian neoplasms. (PubMed id 20377136)1, 4 Heubner M....Siffert W. (2010)
    321. CYP1A1 modifies the effect of maternal exposure to en vironmental tobacco smoke on child behavior. (PubMed id 20855412)1, 4 Hsieh C.J....Chen P.C. (2010)
    322. Combined effects of cigarette smoking, gene polymorph isms and methylations of tumor suppressor genes on non small cell lung cancer: a hospital-based case-control study in China. (PubMed id 20704749)1, 4 Jin Y....Xue S. (2010)
    323. Genetic susceptibility to distinct bladder cancer sub phenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (2010)
    324. Involvement of CYP1A1, GST, 72TP53 polymorphisms in t he pathogenesis of thyroid nodules. (PubMed id 21086258)1, 4 Reis A.A....da Cruz A.D. (2010)
    325. Cigarette smoking, genetic polymorphisms and colorect al cancer risk: the Fukuoka Colorectal Cancer Study. (PubMed id 20534171)1, 4 Nisa H....Terasaka R. (2010)
    326. Maternal genes and facial clefts in offspring: a comp rehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PubMed id 20634891)1, 4 Jugessur A....Murray J.C. (2010)
    327. Genetic polymorphisms in the metabolic pathway and no n-Hodgkin lymphoma survival. (PubMed id 20029944)1, 4 Han X....Zhang Y. (2010)
    328. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)1, 4 Liu C.Y....Christiani D.C. (2010)
    329. CYP1A1 gene polymorphisms as a risk factor for pteryg ium. (PubMed id 20596254)1, 4 Young C.H....Cheng Y.W. (2010)
    330. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1, 4 He C....Hunter D.J. (2010)
    331. Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolis m and breast cancer risk in the NCI breast and prostate cancer cohort consortiu m. (PubMed id 20634197)1, 4 Canzian F....Feigelson H.S. (2010)
    332. Smoking related risk involved in individuals carrying genetic variants of CYP1A1 gene in head and neck cancer. (PubMed id 20887941)1, 4 Sabitha K....Jamil K. (2010)
    333. [Cytochrome P4501A1, glutathione S-transferase M1 and T1 gene polymorphisms in chronic myeloid leukemia]. (PubMed id 21254556)1, 4 Ovsepian V.A....Sherstneva E.S. (2010)
    334. CYP1A1 MSPI (T6235C) gene polymorphism is associated with mortality in acute coronary syndrome patients. (PubMed id 19650794)1, 4 Jarvis M.D....Cameron V.A. (2010)
    335. Polymorphisms in metabolic genes CYP1A1 and GSTM1 and changes in maternal smoking during pregnancy. (PubMed id 19246429)1, 4 Chen X. and Woodcroft K.J. (2009)
    336. Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women. (PubMed id 19174490)1, 4 Cote M.L....Schwartz A.G. (2009)
    337. Phase I and II enzyme polymorphisms as risk factors for Barrett's esophagus and esophageal adenocarcinoma: a systematic review and meta-analysis. (PubMed id 19222528)1, 4 Bull L.M....El-Serag H.B. (2009)
    338. Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. (PubMed id 19339270)1, 4 Canova C....Brennan P. (2009)
    339. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PubMed id 19170196)1, 4 Shen M....Lan Q. (2009)
    340. African American-preponderant single nucleotide polym orphisms (SNPs) and risk of breast cancer. (PubMed id 19679043)1, 4 Kato I....Korczak J.F. (2009)
    341. CYP1A1 and CYP2D6 gene polymorphisms in Israeli Jewis h women with cervical cancer. (PubMed id 20009880)1, 4 Gutman G....Grisaru D. (2009)
    342. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)1, 4 Yerges L.M....Zmuda J.M. (2009)
    343. Genetic variations in xenobiotic metabolic pathway ge nes, personal hair dye use, and risk of non-Hodgkin lymphoma. (PubMed id 19822571)1, 4 Zhang Y....Zheng T. (2009)
    344. [Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like der-matitis induced by trichloroethylene.] (PubMed id 19351467)1, 4 Xu X.Y....Yang L.Q. (2009)
    345. A case-control study of CYP1A1, GSTT1 and GSTM1 gene polymorphisms, pregnancy smoking and fetal growth restriction. (PubMed id 19147266)1, 4 Delpisheh A....Brabin B.J. (2009)
    346. Genome-wide association study identifies eight loci associated with blood pressure. (PubMed id 19430483)1, 4 Newton-Cheh C....Munroe P.B. (2009)
    347. [Role of xenobiotic biotransformation enzymes in resp iratory diseases caused by dust] (PubMed id 20095411)1, 4 Mingazova S.R....Akhmadishina L.Z. (2009)
    348. Genetic polymorphisms of FSHR, CYP17, CYP1A1, CAPN10, INSR, SERPINE1 genes in adolescent girls with polycystic ovary syndrome. (PubMed id 19387820)1, 4 Unsal T....Menevse A. (2009)
    349. Genetic variation of genes for xenobiotic-metabolizin g enzymes and risk of bronchial asthma: the importance of gene-gene and gene-en vironment interactions for disease susceptibility. (PubMed id 19575027)1, 4 Polonikov A.V....Solodilova M.A. (2009)
    350. PTEN identified as important risk factor of chronic o bstructive pulmonary disease. (PubMed id 19625176)1, 4 Hosgood H.D....Lan Q. (2009)
    351. Candidate gene association study of esophageal squamo us cell carcinoma in a high-risk region in Iran. (PubMed id 19826048)1, 4 Akbari M.R....Narod S.A. (2009)
    352. Polymorphisms of drug-metabolizing genes and risk of non-Hodgkin lymphoma. (PubMed id 19899130)1, 4 Kim H.N....Kim H.J. (2009)
    353. [A case-control study of environmental and genetic fa ctors and prostate cancer in Guangdong] (PubMed id 19954068)1, 4 Wu Y.J....Liu Q. (2009)
    354. Risk of malignant pleural mesothelioma and polymorphi sms in genes involved in the genome stability and xenobiotics metabolism. (PubMed id 19751749)1, 4 Gemignani F....Landi S. (2009)
    355. [Relationship between genetic polymorphisms of phase I and phase II metabolizing enzymes and DNA damage of workers exposed to vinyl chloride monomer] (PubMed id 19267064)1, 4 Ji F....Wang W. (2009)
    356. Novel DNA sequence variations of cytochrome P450 genes in the Han Chinese population. (PubMed id 19290787)1, 4 Wang H.H....Chen Y.T. (2009)
    357. Determination of genetic predisposition to patent ductus arteriosus in preterm infants. (PubMed id 19336370)1, 4 Dagle J.M....Murray J.C. (2009)
    358. Quantitative trait loci predicting circulating sex st eroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3). (PubMed id 19574343)1, 4 Ahn J....Hayes R.B. (2009)
    359. Integrative predictive model of coronary artery calci fication in atherosclerosis. (PubMed id 19948975)1, 4 McGeachie M....Ramoni M.F. (2009)
    360. Racial disparity in pathophysiologic pathways of pret erm birth based on genetic variants. (PubMed id 19527514)1, 4 Menon R....Thorsen P. (2009)
    361. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (2009)
    362. CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification. (PubMed id 19276377)1, 4 Aldrich M.C....Wiencke J.K. (2009)
    363. Polymorphism of the CYP1A1*2A gene and susceptibility to lung cancer in a Brazilian population. (PubMed id 19750329)1, 4 Honma H.N....Zambon L. (2009)
    364. A gene-based risk score for lung cancer susceptibilit y in smokers and ex-smokers. (PubMed id 19789190)1, 4 Young R.P....Gamble G.D. (2009)
    365. Genetic polymorphisms of cytochrome p450 and matrix m etalloproteinase in chronic obstructive pulmonary disease. (PubMed id 19507017)1, 4 Cheng S.L....Yang P.C. (2009)
    366. Paternal smoking, genetic polymorphisms in CYP1A1 and childhood leukemia risk. (PubMed id 18691756)1, 4 Lee K.M....Kang D. (2009)
    367. Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. (PubMed id 19630952)1, 4 Crandall C.J....Sinsheimer J.S. (2009)
    368. [The association of TCR-mutant cells with DNA polymor phism in women residing in radiation polluted regions of the Russian Federation ] (PubMed id 19799358)1, 4 Zamulaeva I.A....Rubanovich A.V. (2009)
    369. Four polymorphisms in cytochrome P450 1A1 (CYP1A1) ge ne and breast cancer risk: a meta-analysis. (PubMed id 20035380)1, 4 Sergentanis T.N. and Economopoulos K.P. (2009)
    370. Aromatic DNA adducts and polymorphisms in metabolic genes in healthy adults: findings from the EPIC-Spain cohort. (PubMed id 19307236)1, 4 Agudo A....GonzA!lez C.A. (2009)
    371. Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994. (PubMed id 18936436)1, 4 Chang M.H....Khoury M.J. (2009)
    372. Genetic polymorphisms in glutathione S-transferases and cytochrome P450s, tobacco smoking, and risk of non-Hodgkin lymphoma. (PubMed id 19338043)1, 4 Kilfoy B.A....Zhang Y. (2009)
    373. Effect modification of endocrine disruptors and testi cular germ cell tumour risk by hormone-metabolizing genes. (PubMed id 19627379)1, 4 Chia V.M....McGlynn K.A. (2009)
    374. CYP1A1 polymorphisms and risk of lung cancer in the e thnic Kashmiri population. (PubMed id 19827888)1, 4 Shaffi S.M....Siddiqi M.A. (2009)
    375. Polymorphisms of CYP1A1 and GSTM1 and laryngeal cancer risk: evidence-based meta-analyses. (PubMed id 19252926)1, 4 Zhuo W.L....Chen Z.T. (2009)
    376. Relation of genetic polymorphisms in the cytochrome P 450 gene with clopidogrel resistance after drug-eluting stent implantation in K oreans. (PubMed id 19576320)1, 4 Lee J.M....Jang Y. (2009)
    377. Possible Risk Modification by Polymorphisms of Estrog en Metabolizing Genes in Familial Breast Cancer Susceptibility in an Indian Pop ulation. (PubMed id 19863350)1, 4 Syamala V.S....Ankathil R. (2009)
    378. Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. (PubMed id 19127255)1, 4 Pearce C.L.... . (2009)
    379. Genes related to sex steroids, neural growth, and soc ial-emotional behavior are associated with autistic traits, empathy, and Asperg er syndrome. (PubMed id 19598235)1, 4 Chakrabarti B....Baron-Cohen S. (2009)
    380. Polymorphism in cytochrome P4501A1 is significantly a ssociated with head and neck cancer risk. (PubMed id 19639480)1, 4 Singh A.P....Parmar D. (2009)
    381. Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways. (PubMed id 18992263)1, 4 Slattery M.L....Samowitz W.S. (2009)
    382. Phase I metabolic genes and risk of lung cancer: mult iple polymorphisms and mRNA expression. (PubMed id 19479063)1, 4 Rotunno M....Landi M.T. (2009)
    383. CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and neck cancer. (PubMed id 17611777)1, 4 Boccia S....Ricciardi G. (2008)
    384. Polymorphisms of selected Xenobiotic Genes contribute to the development of Papillary Thyroid Cancer susceptibility in Middle Eastern population. (PubMed id 18601742)1, 4 Siraj A.K....Al-Kuraya K.S. (2008)
    385. Relationship between genetic polymorphism of CYP1A1 at codon 462 (Ile462Val) in colorectal cancer. (PubMed id 18409146)1, 4 Pereira Serafim P.V....Manoukias Forones N. (2008)
    386. Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. (PubMed id 18818748)1, 4 Velez D.R....Menon R. (2008)
    387. Polymorphisms of estrogen-related genes jointly confer susceptibility to human spermatogenic defect. (PubMed id 18980759)1, 4 Su M.T....Kuo P.L. (2008)
    388. Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes. (PubMed id 18632753)1, 4 Figueroa J.D....Rothman N. (2008)
    389. Genetic variation in hormone metabolizing genes and risk of testicular germ cell tumors. (PubMed id 18415690)1, 4 Figueroa J.D....McGlynn K.A. (2008)
    390. CYP1A1 Ile462Val and GSTT1 modify the effect of cord blood cotinine on neurodevelopment at 2 years of age. (PubMed id 18577398)1, 4 Hsieh C.J....Chen P.C. (2008)
    391. Genetic susceptibilities in the association between maternal exposure to tobacco smoke and the risk of nonsyndromic oral cleft. (PubMed id 18698632)1, 4 Chevrier C....Cordier S. (2008)
    392. Molecular aspects of osteopathy in type 1 Gaucher disease: correlation between genetics and bone density. (PubMed id 18317771)1, 4 Arnheim E....Altarescu G. (2008)
    393. Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia. (PubMed id 19074885)1, 4 Enjuanes A....Campo E. (2008)
    394. Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population. (PubMed id 18510611)1, 4 Ikeda S....Tsugane S. (2008)
    395. Effect of genetic predisposition on the risk of gallbladder cancer in Hungary. (PubMed id 18990008)1, 4 Kimura A....Nakamura K. (2008)
    396. Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes. (PubMed id 18642288)1, 4 Buch S.C....Romkes M. (2008)
    397. Polymorphisms in genes involved in sex hormone metabolism, estrogen plus progestin hormone therapy use, and risk of postmenopausal breast cancer. (PubMed id 18628428)1, 4 Diergaarde B....White E. (2008)
    398. Association of estrogen-related polymorphisms with age at menarche, age at final menstrual period, and stages of the menopausal transition. (PubMed id 17589376)1, 4 Mitchell E.S....Woods N.F. (2008)
    399. CYP1A1 polymorphisms and the risk of upper aerodigestive tract cancers in an Indian population. (PubMed id 18767181)1, 4 Sam S.S....Chandrasekaran A. (2008)
    400. Meta-analysis and pooled analysis of GSTM1 and CYP1A1 polymorphisms and oral and pharyngeal cancers: a HuGE-GSEC review. (PubMed id 18496222)1, 4 Varela-Lema L....Ragin C.C. (2008)
    401. [Associations of the genotypes of the CYP1A1 gene with predisposition to hydatid disease caused by Echinococcus granulosus strain G1] (PubMed id 18819424)1, 4 Lukmanova G.I....Viktorova T.V. (2008)
    402. Maternal smoking and oral clefts: the role of detoxification pathway genes. (PubMed id 18449058)1, 4 Lie R.T....Vindenes H. (2008)
    403. Passive smoking, cytochrome P450 gene polymorphisms and dysmenorrhea. (PubMed id 18437510)1, 4 Lei L....Chen D. (2008)
    404. Distribution of CYP1A1*2A polymorphism in adult patients with acute lymphoblastic leukemia in a Mexican population. (PubMed id 18203634)1, 4 Gallegos-Arreola M.P....Zuniga-Gonzalez G.M. (2008)
    405. Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancer. (PubMed id 18941913)1, 4 Kotsopoulos J....Tworoger S.S. (2008)
    406. [Analysis of the cytochrome P450 (CYP1A1) gene polymorphism in the ethnic groups of the Republic of Bashkortostan] (PubMed id 19178087)1, 4 Kochetova O.V....Victorova T.V. (2008)
    407. Relation of PON1 and CYP1A1 genetic polymorphisms to clinical findings in a cross-sectional study of a Greek rural population professionally exposed to pesticides. (PubMed id 19022366)1, 4 Tsatsakis A.M....Kafatos A. (2008)
    408. Association of cytochrome P450, glutathione S-transferase and N-acetyl transferase 2 gene polymorphisms with incidence of acute myeloid leukemia. (PubMed id 18287869)1, 4 Majumdar S....Dasgupta U.B. (2008)
    409. Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk. (PubMed id 18990750)1, 4 Cotterchio M....Harper P.A. (2008)
    410. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)1, 4 Hosgood H.D....Lan Q. (2008)
    411. Polymorphisms in genes related to activation or detoxification of carcinogens might interact with smoking to increase renal cancer risk: results from The Netherlands Cohort Study on diet and cancer. (PubMed id 17982751)1, 4 Smits K.M....van den Brandt P.A. (2008)
    412. Assessment of interactions between PAH exposure and genetic polymorphisms on PAH-DNA adducts in African American, Dominican, and Caucasian mothers and newborns. (PubMed id 18268125)1, 4 Wang S....Perera F.P. (2008)
    413. Coffee consumption, genetic susceptibility and bladder cancer risk. (PubMed id 18798002)1, 4 Villanueva C.M....Kogevinas M. (2008)
    414. CYP1A1 *2B and *4 polymorphisms are associated with lung cancer susceptibility in Mexican patients. (PubMed id 18409147)1, 4 Gallegos-Arreola M.P....Zuniga-Gonzalez G.M. (2008)
    415. Head and neck squamous-cell cancer and its association with polymorphic enzymes of xenobiotic metabolism and repair. (PubMed id 18569591)1, 4 Harth V....Ickstadt K. (2008)
    416. Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. (PubMed id 19019335)1, 4 Velez D.R....Menon R. (2008)
    417. Influence of genetic factors on toluene diisocyanate-related symptoms: evidence from a cross-sectional study. (PubMed id 18447907)1, 4 Broberg K....Littorin M. (2008)
    418. Cytogenetic effects induced by Prestige oil on human populations: The role of polymorphisms in genes involved in metabolism and DNA repair. (PubMed id 18495522)1, 4 Perez-Cadahia B....Mendez J. (2008)
    419. Association of CYP1A1 Msp1 polymorphism with tobacco-related risk of gallbladder cancer in a north Indian population. (PubMed id 18287863)1, 4 Pandey S.N....Mittal B. (2008)
    420. Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma. (PubMed id 18636124)1, 4 Skibola C.F....Smith M.T. (2008)
    421. Profile of polymorphisms of drug-metabolising enzymes and the risk of therapy-related leukaemia. (PubMed id 17367411)1, 4 Bolufer P....Sanz M.A. (2007)
    422. Cytochrome P450IA1 polymorphisms along with PM(10) exposure contribute to the risk of birth weight reduction. (PubMed id 17706398)1, 4 Suh Y.J....Ha E.H. (2007)
    423. Genetic susceptibility according to three metabolic pathways in cancers of the lung and bladder and in myeloid leukemias in nonsmokers. (PubMed id 17496311)1, 4 Vineis P....Autrup H. (2007)
    424. Polymorphisms of the COL1A2, CYP1A1 and HS1,2 Ig enhancer genes in the Tuaregs from Libya. (PubMed id 17620151)1, 4 Martinez-Labarga C....Rickards O. (2007)
    425. [Combined effects of genetic polymorphisms in cytochrome P450s and GSTM1 on lung cancer susceptibility] (PubMed id 18261353)1, 4 Gu Y.F....Gu S.X. (2007)
    426. CYP1A1 and GSTM1/T1 genetic variation in predicting risk for cerebral infarction. (PubMed id 17873299)1, 4 Moon K.S....Um J.Y. (2007)
    427. PAH-DNA adducts in environmentally exposed population in relation to metabolic and DNA repair gene polymorphisms. (PubMed id 17412371)1, 4 Binkova B....Sram R.J. (2007)
    428. Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions. (PubMed id 16956909)1, 4 Manuguerra M....Vineis P. (2007)
    429. Polymorphisms of cytochrome P450 1A1, glutathione S-transferase class mu, and tumour protein p53 genes and the risk of developing gallbladder cancer in Japanese. (PubMed id 17531965)1, 4 Tsuchiya Y....Yamamoto M. (2007)
    430. Combinations of cytochrome P-450 genotypes and risk of early-onset lung cancer in Caucasians and African Americans: a population-based study. (PubMed id 17174438)1, 4 Cote M.L....Schwartz A.G. (2007)
    431. CYP17 and COMT gene polymorphisms can influence bone directly, or indirectly through their effects on endogenous sex steroids, in postmenopausal Japanese women. (PubMed id 16971197)1, 4 Gorai I....Chaki O. (2007)
    432. The influence of metabolic gene polymorphisms on urinary 1-hydroxypyrene concentrations in Chinese coke oven workers. (PubMed id 17498780)1, 4 Chen B....Zhou Y. (2007)
    433. Ovarian cancer risk and polymorphisms involved in estrogen catabolism. (PubMed id 17372243)1, 4 Holt S.K....Chen C. (2007)
    434. Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: a case-control study in an Italian population. (PubMed id 17996038)1, 4 Boccia S....Ricciardi G. (2007)
    435. The influence of genetic polymorphisms in Ahr, CYP1A1, CYP1A2, CYP1B1, GST M1, GST T1 and UGT1A1 on urine 1-hydroxypyrene glucuronide concentrations in healthy subjects from Rio Grande do Sul, Brazil. (PubMed id 16864595)1, 4 Abnet C.C....Dawsey S.M. (2007)
    436. Passive smoking, metabolic gene polymorphisms, and infant birth weight in a prospective cohort study of Chinese women. (PubMed id 17526865)1, 4 Wu T....Chen D. (2007)
    437. Interaction between cytochrome P450 gene polymorphisms and serum organochlorine TEQ levels in the risk of endometriosis. (PubMed id 17449539)1, 4 Tsuchiya M....Tsugane S. (2007)
    438. The GST deletions and NQO1*2 polymorphism confers interindividual variability of response to treatment in patients with acute myeloid leukemia. (PubMed id 17118447)1, 4 Barragan E....Sanz M.A. (2007)
    439. CYP1A1 gene polymorphisms in modifying the association between passive smoking and primary dysmenorrhea. (PubMed id 17728147)1, 4 Li N....Chen D. (2007)
    440. Effects of metabolic genotypes on intermediary biomarkers in subjects exposed to PAHS: results from the EXPAH study. (PubMed id 17403528)1, 4 Garte S....Farmer P.B. (2007)
    441. Associations among genetic susceptibility, DNA damage, and pregnancy outcomes of expectant mothers exposed to environmental tobacco smoke. (PubMed id 17610937)1, 4 Wu F.Y....Lai J.S. (2007)
    442. Impact of air pollution and genotype variability on DNA damage in Prague policemen. (PubMed id 17590289)1, 4 Novotna B....Sram R.J. (2007)
    443. Glutathione-S-transferase M1 and T1 and cytochrome P1A1 genetic polymorphisms and susceptibility to cervical intraepithelial neoplasia in Greek women. (PubMed id 18090121)1, 4 Agorastos T....Bontis J.N. (2007)
    444. Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race. (PubMed id 17548691)1, 4 Nock N.L....Rybicki B.A. (2007)
    445. CYP1A1 Msp1 T/C polymorphism in esophageal cancer: no association and risk modulation. (PubMed id 18074679)1, 4 Jain M....Mittal B. (2007)
    446. Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary. (PubMed id 17695473)1, 4 Kiss I....Ember I. (2007)
    447. Evidence of gene gene interactions in lung carcinogenesis in a large pooled analysis. (PubMed id 17307802)1, 4 Vineis P....Taioli E. (2007)
    448. Passive smoking, Cyp1A1 gene polymorphism and dysmenorrhea. (PubMed id 17566695)1, 4 Liu H....Chen D. (2007)
    449. Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition. (PubMed id 17164366)1, 4 Agudo A....Gonzalez C.A. (2006)
    450. Nicotine metabolizing genes GSTT1 and CYP1A1 in sudden infant death syndrome. (PubMed id 16763966)1, 4 Rand C.M....Berry-Kravis E.M. (2006)
    451. Polymorphisms in the estrogen synthesis and metabolism pathways and symptoms during the menopausal transition: observations from the Seattle Midlife Women's Health Study. (PubMed id 16977255)1, 4 Woods N.F....Farin F.M. (2006)
    452. Cytochrome P2A13 and P1A1 gene polymorphisms are associated with the occurrence of uterine leiomyoma. (PubMed id 16835796)1, 4 Herr D....Pietrowski D. (2006)
    453. Comparison of polymorphisms in genes involved in polycyclic aromatic hydrocarbon metabolism with urinary phenanthrene metabolite ratios in smokers. (PubMed id 17035385)1, 4 Hecht S.S....Hatsukami D.K. (2006)
    454. Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer. (PubMed id 16721740)1, 4 Gattas G.J....Wunsch-Filho V. (2006)
    455. Smoking and susceptibility to thyroid cancer: an inverse association with CYP1A1 allelic variants. (PubMed id 17158763)1, 4 Bufalo N.E....Ward L.S. (2006)
    456. CYP1A1 gene polymorphism as a risk factor for cervical intraepithelial neoplasia and invasive cervical cancer. (PubMed id 16403567)1, 4 Taskiran C....Ayhan A. (2006)
    457. [Polymorphism of CYP1A1 gene Msp I site in the Mongolian and Han nationality populations of Inner Mongolia of China] (PubMed id 16767678)1, 4 Chang F.H. and Hu T.M. (2006)
    458. Metabolic genotypes as modulators of asbestos-related pleural malignant mesothelioma risk: a comparison of Finnish and Italian populations. (PubMed id 16697254)1, 4 Neri M....Garte S. (2006)
    459. Association of DNA adducts and genotypes with birth w eight. (PubMed id 16837240)1, 4 Sram R.J....Topinka J. (2006)
    460. Colorectal cancer and genetic polymorphisms of CYP1A1, GSTM1 and GSTT1: a case-control study in the Grampian region of Scotland. (PubMed id 16823842)1, 4 Little J....Cassidy J. (2006)
    461. Multilocus genotypes spanning estrogen metabolism associated with breast cancer and fibroadenoma. (PubMed id 16608396)1, 4 Corder E.H. and Hefler L.A. (2006)
    462. Gene-environment interaction involved in oral carcinogenesis: molecular epidemiological study for metabolic and DNA repair gene polymorphisms. (PubMed id 16393248)1, 4 Sugimura T....Ishizaki K. (2006)
    463. Polymorphisms in polycyclic aromatic hydrocarbon metabolism and conjugation genes, interactions with smoking and prostate cancer risk. (PubMed id 16614120)1, 4 Nock N.L....Witte J.S. (2006)
    464. Genetic polymorphisms in xenobiotic clearance genes and their influence on disease expression in hereditary nonpolyposis colorectal cancer patients. (PubMed id 17119063)1, 4 Talseth B.A....Scott R.J. (2006)
    465. Interaction between CYP1A1 T3801C and AHR G1661A polymorphisms according to smoking status on blood pressure in the Stanislas cohort. (PubMed id 17053541)1, 4 Gambier N....Visvikis-Siest S. (2006)
    466. Joint effects of the CYP1A1 MspI, ERalpha PvuII, and ERalpha XbaI polymorphisms on the risk of breast cancer: results from a population-based case-control study in Shanghai, China. (PubMed id 16492926)1, 4 Shen Y....Gao E. (2006)
    467. CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal. (PubMed id 16949388)1, 4 Sowers M.R....McConnell D.S. (2006)
    468. Estrogen sulfation genes, hormone replacement therapy, and endometrial cancer risk. (PubMed id 16985250)1, 4 Rebbeck T.R....Strom B.L. (2006)
    469. Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population. (PubMed id 16771603)1, 4 Bosch T.M....Beijnen J.H. (2006)
    470. CYP1A1 and GSTP1 polymorphisms in an oral cancer case-control study. (PubMed id 17160265)1, 4 Leichsenring A....Ribeiro E.M. (2006)
    471. Multiplex PCR with confronting two-pair primers for CYP1A1 Ile462Val, GSTM1, GSTT1, and NQO1 C609T. (PubMed id 16235998)1, 4 Kawai S....Hamajima N. (2005)
    472. The CYP1A1 genotype may alter the association of meat consumption patterns and preparation with the risk of colorectal cancer in men and women. (PubMed id 15671210)1, 4 Murtaugh M.A....Slattery M.L. (2005)
    473. Ten estrogen-related polymorphisms and endometriosis: a study of multiple gene-gene interactions. (PubMed id 16260521)1, 4 Huber A....Tempfer C.B. (2005)
    474. Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study. (PubMed id 16009381)1, 4 Raimondi S....Taioli E. (2005)
    475. Estrogen-metabolizing gene polymorphisms and lipid levels in women with different hormonal status. (PubMed id 16130011)1, 4 Almeida S....Hutz M.H. (2005)
    476. Cytochrome P4501A1 and glutathione S transferase gene polymorphisms in patients with aplastic anemia in India. (PubMed id 16227674)1, 4 Poonkuzhali B....Chandy M. (2005)
    477. Ten polymorphisms of estrogen-metabolizing genes and a family history of colon cancer--an association study of multiple gene-gene interactions. (PubMed id 16202920)1, 4 Huber A....Tempfer C. (2005)
    478. Interactions between CYP1A1 polymorphisms and exposure to environmental tobacco smoke in the modulation of lymphocyte bulky DNA adducts and chromosomal aberrations. (PubMed id 15459023)1, 4 Georgiadis P....Kyrtopoulos S.A. (2005)
    479. Estrogen metabolizing polymorphisms and breast cancer risk among older white women. (PubMed id 16142442)1, 4 Modugno F....Cauley J.A. (2005)
    480. Association of genetic polymorphisms with serum estrogens measured multiple times during a 2-year period in premenopausal women. (PubMed id 15941966)1, 4 Lurie G....Le Marchand L. (2005)
    481. Estrogen-metabolizing gene COMT polymorphism synergistic APOE epsilon4 allele increases the risk of Alzheimer disease. (PubMed id 15591802)1, 4 Wang P.N....Chi C.W. (2005)
    482. [A case-control study on the association between genetic polymorphisms of metabolic enzymes and the risk of colorectal cancer] (PubMed id 16471212)1, 4 Chen K....Yao K.Y. (2005)
    483. Cytochrome P4501A1 polymorphisms in the Amerindian and Mestizo populations of Mexico. (PubMed id 15376230)1, 4 Fragoso J.M....Vargas-Alarcon G. (2005)
    484. Phase I/II enzyme gene polymorphisms and esophageal cancer risk: a meta-analysis of the literature. (PubMed id 15849806)1, 4 Yang C.X....Tajima K. (2005)
    485. Polymorphism of CYPIA1 and GSTM1 genes associated with susceptibility of gastric cancer in Shandong Province of China. (PubMed id 16270381)1, 4 Li H....Li H.Q. (2005)
    486. CYP1A1 Val462 and NQO1 Ser187 polymorphisms, cigarette use, and risk for colorectal adenoma. (PubMed id 15731166)1, 4 Hou L....Hayes R.B. (2005)
    487. CYP1A1 polymorphisms and risk of lung cancer in non-smoking Chinese women: influence of environmental tobacco smoke exposure and GSTM1/T1 genetic variation. (PubMed id 15953982)1, 4 Ng D.P....Seow A. (2005)
    488. Risk of non-small cell lung cancer and the cytochrome P4501A1 Ile462Val polymorphism. (PubMed id 15986113)1, 4 Larsen J.E....Fong K.M. (2005)
    489. Analysis of the AhR, ARNT, and AhRR gene polymorphisms: genetic contribution to endometriosis susceptibility and severity. (PubMed id 16084889)1, 4 Tsuchiya M.... Ikenoue T. (2005)
    490. Interaction models of CYP1A1, GSTM1 polymorphisms and tobacco smoking in intestinal gastric cancer. (PubMed id 16273625)1, 4 Shen J....Wang X.R. (2005)
    491. Polymorphisms of drug-metabolizing enzymes and risk of childhood acute lymphoblastic leukemia. (PubMed id 15981231)1, 4 Pakakasama S....Hongeng S. (2005)
    492. Estrogen-metabolizing gene polymorphisms and age at natural menopause in Caucasian women. (PubMed id 15774541)1, 4 Hefler L.A....Tempfer C.B. (2005)
    493. Smoking habit and genetic factors associated with lung cancer in a population highly exposed to arsenic. (PubMed id 16099114)1, 4 Adonis M....Gil L. (2005)
    494. Association study of detoxification genes in age related macular degeneration. (PubMed id 15774926)1, 4 Esfandiary H....Hughes A.E. (2005)
    495. CYP1A1 and CYP1B1 polymorphisms and risk of lung cancer among never smokers: a population-based study. (PubMed id 16051642)1, 4 Wenzlaff A.S....Schwartz A.G. (2005)
    496. Genetic polymorphisms and the effect of cigarette smoking in the comet assay. (PubMed id 16037119)1, 4 Hoffmann H....Speit G. (2005)
    497. Genetic factors in catechol estrogen metabolism in relation to the risk of endometrial cancer. (PubMed id 15734958)1, 4 Doherty J.A....Chen C. (2005)
    498. Estrogen bioactivation, genetic polymorphisms, and ovarian cancer. (PubMed id 16284375)1, 4 Sellers T.A....Adjei A.A. (2005)
    499. Relationship among metabolizing genes, smoking and alcohol used as modifier factors on prostate cancer risk: exploring some gene-gene and gene-environment interactions. (PubMed id 15756908)1, 4 Caceres D.D....Quinones L. (2005)
    500. Associations between breast cancer susceptibility gene polymorphisms and clinicopathological features. (PubMed id 14734460)1, 4 Han W....Noh D.Y. (2004)
    501. Metabolic polymorphisms, smoking, and oral cancer in Puerto Rico. (PubMed id 15206494)1, 4 Xie H....Hayes R.B. (2004)
    502. Polymorphisms in glutathione S-transferases GSTM1, GSTT1 and GSTP1 and cytochromes P450 CYP2E1 and CYP1A1 and susceptibility to cirrhosis or pancreatitis in alcoholics. (PubMed id 15215328)1, 4 Burim R.V....Takahashi C.S. (2004)
    503. Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 gene point mutations in Japanese patients with gastric cancer. (PubMed id 15064998)1, 4 Suzuki S....Oda Y. (2004)
    504. Estrogen-metabolizing gene polymorphisms in the assessment of breast carcinoma risk and fibroadenoma risk in Caucasian women. (PubMed id 15241822)1, 4 Hefler L.A....Koelbl H. (2004)
    505. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    506. Chromosome and DNA damage analysis in individuals occupationally exposed to pesticides with relation to genetic polymorphism for CYP 1A1 gene in Ecuador. (PubMed id 15279831)1, 4 Paz-y-Mino C....Leone P.E. (2004)
    507. GSTM1, GSTT1, GSTP1 and CYP1A1 genetic polymorphisms and susceptibility to esophageal cancer in a French population: different pattern of squamous cell carcinoma and adenocarcinoma. (PubMed id 15526353)1, 4 Abbas A....Sichel F. (2004)
    508. Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population. (PubMed id 15469410)1, 2 Solus J.F.... Dawson E.P. (2004)
    509. Genetic susceptibility and environmental factors of esophageal cancer in Xi'an. (PubMed id 15052670)1, 4 Wang A.H....Xu D.Z. (2004)
    510. Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke. (PubMed id 15093273)1, 4 Georgiadis P....Kyrtopoulos S.A. (2004)
    511. [Gene-gene and gene-environment interactions as modifier factors of prostatic cancer risk: 'a case-only' design study] (PubMed id 15478298)1, 4 Caceres D....Quinones L. (2004)
    512. Polymorphisms of estrogen-metabolizing genes and risk of hepatocellular carcinoma in Taiwan females. (PubMed id 15341023)1, 4 Yin P.H....Chi C.W. (2004)
    513. CYP1A1 alleles in women with focal nodular hyperplasia of the liver (FNH). (PubMed id 15180167)1, 4 Lazar A....Fuhr U. (2004)
    514. Polymorphisms in genes coding for enzymes metabolizing smoking-derived substances and the risk of periodontitis. (PubMed id 15491310)1, 4 Kim J.S....Park K.K. (2004)
    515. Cytochrome p450 1Al gene polymorphisms in patients with psoriatic arthritis. (PubMed id 15124938)1, 4 Yen J.H....Liu H.W. (2004)
    516. [A case control study on the impact of CYP450 MSPI and GST-M1 polymorphisms on the risk of lung cancer] (PubMed id 15059326)1, 4 Wang B.G....Wang D.Q. (2004)
    517. Cytochrome P450 1A1 and manganese superoxide dismutase gene polymorphisms in Behcet's disease. (PubMed id 15088300)1, 4 Yen J.H....Liu H.W. (2004)
    518. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. (PubMed id 15128046)1, 3 Nelson D.R....Nebert D.W. (2004)
    519. Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison. (PubMed id 15327835)1, 4 Sepehr A....Dawsey S.M. (2004)
    520. Association of metabolic gene polymorphisms with tobacco consumption in healthy controls. (PubMed id 15069692)1, 4 Smits K.M....Taioli E. (2004)
    521. Influence of CYP1A1, GSTM1, GSTT1, and NQO1 genotypes and cumulative smoking dose on lung cancer risk in a Swedish population. (PubMed id 15184245)1, 4 Alexandrie A.K....Rannug A. (2004)
    522. [The relationship between genetic polymorphism of metabolizing enzymes and the genetic susceptibility to lung cancer] (PubMed id 15769360)1, 4 Li W.Y....Zhan X.P. (2004)
    523. [Detecting genetic polymorphisms of CYP1 A1 and GSTM1 simultaneously with oligonucleotide microarray] (PubMed id 15552037)1, 4 Liu S.Z....Xie Y. (2004)
    524. Cytochrome P450 1A1 (CYP1A1) T6325C polymorphism might modulate essential hypertension-associated stroke risk. (PubMed id 15185560)1, 4 Lanca V....Bicho M.P. (2004)
    525. [Polymorphism of genes for xenobiotic metabolism in petrochemical workers] (PubMed id 14582397)1, 4 Makarova O.V....Karimova L.K. (2003)
    526. Cytochrome P450 1A1 and manganese superoxide dismutase genes polymorphisms in ankylosing spondylitis. (PubMed id 12880680)1, 4 Yen J.H....Liu H.W. (2003)
    527. Polymorphisms in steroid hormone pathway genes and mammographic density. (PubMed id 12602902)1, 4 Haiman C.A....Byrne C. (2003)
    528. Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years. (PubMed id 12690010)1, 4 Taioli E....Garte S. (2003)
    529. Novel nonsynonymous polymorphisms of the CYP1A1 Gene in Japanese. (PubMed id 15618738)1, 2 Saito M.... Kamataki T. (2003)
    530. CYP1A1 T3801 C polymorphism and lung cancer: a pooled analysis of 2451 cases and 3358 controls. (PubMed id 12594823)1, 4 Vineis P....Taioli E. (2003)
    531. Allelic variants of drug metabolizing enzymes as risk factors in psoriasis. (PubMed id 12713578)1, 4 Richter-Hintz D....Esser C. (2003)
    532. Association of genetic polymorphisms in CYP19 and CYP1A1 with the oestrogen receptor-positive breast cancer risk. (PubMed id 14602139)1, 4 Miyoshi Y....Noguchi S. (2003)
    533. A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus. (PubMed id 12732844)1, 4 Watanabe I....Koga T. (2003)
    534. Manganese superoxide dismutase and cytochrome P450 1A1 genes polymorphisms in rheumatoid arthritis in Taiwan. (PubMed id 12590982)1, 4 Yen J.H....Liu H.W. (2003)
    535. Associations between genetic polymorphisms of Phase I and II metabolizing enzymes, p53 and susceptibility to esophageal adenocarcinoma. (PubMed id 12670526)1, 4 Casson A.G....McLaughlin J. (2003)
    536. CYP1A1 and CYP2D6 polymorphism and risk of lung cancer in a North Indian population. (PubMed id 14602525)1, 4 Sobti R.C....Janmeja A. (2003)
    537. Cytochrome P450 1A1 and manganese superoxide dismutase genes polymorphisms in reactive arthritis. (PubMed id 14687717)1, 4 Yen J.H....Liu H.W. (2003)
    538. GST M1 and CYP1A1 gene polymorphism and daily fruit consumption in Turkish patients with non-small cell lung carcinomas. (PubMed id 14758730)1, 4 Ozturk O....Gurses A. (2003)
    539. Association of the genetic polymorphism in cytochrome P450 (CYP) 1A1 with risk of familial prostate cancer in a Japanese population: a case-control study. (PubMed id 12767526)1, 4 Suzuki K....Yamanaka H. (2003)
    540. Genetic susceptibility for emphysematous changes of the lung in Japanese. (PubMed id 12579334)1, 4 Budhi A....Kohno N. (2003)
    541. CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis. (PubMed id 12771031)1, 4 Hung R.J....Taioli E. (2003)
    542. Role of DNA mismatch repair genetic polymorphisms in the risk of childhood acute lymphoblastic leukaemia. (PubMed id 14510941)1, 4 Mathonnet G....Sinnett D. (2003)
    543. Allele Frequencies of 25 Polymorphisms Pertaining to Cancer Risk for Japanese, Koreans and Chinese. (PubMed id 12718576)1, 4 Hamajima N....Tajima K. (2002)
    544. Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to oral cavity cancer. (PubMed id 12110344)1, 4 Hahn M....Eckelt U. (2002)
    545. Relationship of tobacco smoking CYP1A1 GSTM1 gene polymorphism and esophageal cancer in Xi'an. (PubMed id 11833070)1, 4 Wang A.H....Chen Q.S. (2002)
    546. Effect of germ-line genetic variation on breast cancer survival in a population-based study. (PubMed id 12036913)1, 4 Goode E.L....Pharoah P.P. (2002)
    547. Meat intake, metabolic genes and colorectal cancer. (PubMed id 12484238)1, 4 Le Marchand L. (2002)
    548. Genetic polymorphisms of cytochrome P450 1A1 and risk of gallbladder cancer. (PubMed id 12071517)1, 4 Tsuchiya Y....Yamamoto M. (2002)
    549. Breast cancer risk associated with CYP1A1 genetic polymorphisms in Japanese women. (PubMed id 12100112)1, 4 Miyoshi Y....Noguchi S. (2002)
    550. [Susceptibility to endometriosis in women of Han Nationality in Guangdong Province associated with Msp I polymorphisms of cytochrome P450 1A1 gene] (PubMed id 12297440)1, 4 Peng D.X....Lin J.M. (2002)
    551. [Influence of glutathione s-transferase and cytochrome p450 polymorphisms on prognosis of head and neck cancer] (PubMed id 12063626)1, 4 Matthias C....Strange R.C. (2002)
    552. [Polymorphic genes of xenobiotic-metabolizing enzymes associated with bronchial asthma in genetically predisposed children] (PubMed id 12018173)1, 4 Vavilin V.A....Gavalov S.M. (2002)
    553. Detection of known and two novel (M331I and R464S) missense mutations in the human CYP1A1 gene in a French Caucasian population. (PubMed id 11295847)1, 2 Chevalier D.... Broly F. (2001)
    554. Polymorphisms of drug-metabolizing enzymes in healthy nonagenarians and centenarians: difference at GSTT1 locus. (PubMed id 11162685)1, 4 Taioli E....Garte S. (2001)
    555. Increased DNA alterations in atherosclerotic lesions of individuals lacking the GSTM1 genotype. (PubMed id 11259393)1, 4 Izzotti A....De Flora S. (2001)
    556. Genetic and environmental interactions on oral cancer in Southern Thailand. (PubMed id 11246217)1, 4 Kietthubthew S....Au W.W. (2001)
    557. [Analysis on associations of cytochrome P450 1A1-Hinc II and glutathion S-transferase-theta with primary dysmenorrhea] (PubMed id 11172643)1, 4 Wu D....Xu X. (2001)
    558. Polymorphisms in CYP1A1 and smoking: no association with breast cancer risk. (PubMed id 11698341)1, 4 Basham V.M....Dunning A.M. (2001)
    559. Relationship between glutathione S-transferase M1, P1 and T1 polymorphisms and early onset prostate cancer. (PubMed id 11434510)1, 4 Kote-Jarai Z....Eeles R. (2001)
    560. Glutathione-S-transferase gene polymorphisms in colorectal cancer patients: interaction between GSTM1 and GSTM3 allele variants as a risk-modulating factor. (PubMed id 11408349)1, 4 Loktionov A....Bingham S.A. (2001)
    561. Glutathione S-transferase genotypes and allergic responses to diisocyanate exposure. (PubMed id 11470996)1, 4 Piirila P....Hirvonen A. (2001)
    562. Polymorphisms in glutathione S-transferases are associated with altered risk of nonmelanoma skin cancer in renal transplant recipients: a preliminary analysis. (PubMed id 11511301)1, 4 Ramsay H.M....Fryer A.A. (2001)
    563. Effect of glutathione S-transferase M1 genotype on progression of atherosclerosis in lifelong male smokers. (PubMed id 11500195)1, 4 de Waart F.G....Stalenhoef A.F. (2001)
    564. CYP1A1, GSTM1, and GSTT1 polymorphisms and the risk of cervical squamous intraepithelial lesions in a multiethnic population. (PubMed id 11330960)1, 4 Goodman M.T....Le Marchand L. (2001)
    565. [Genetic predisposition to development of toxic liver cirrhosis caused by alcohol] (PubMed id 11436564)1, 4 Spitsyn V.A....Afanas'eva I.S. (2001)
    566. Role of genetic factors in development and progression of non-Hodgkin's lymphomas. (PubMed id 11503278)1, 4 Soucek P. (2001)
    567. Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation. (PubMed id 11207026)1, 2 Corchero J.... Gonzalez F.J. (2001)
    568. CYP 1A1 polymorphism and risk of lung cancer in relation to tobacco smoking: a case-control study in China. (PubMed id 11159735)1, 4 Song N....Lin D. (2001)
    569. Influence of antioxidants and the CYP1A1 isoleucine to valine polymorphism on the smoking--lung cancer association. (PubMed id 11396202)1, 4 Ratnasinghe D....Taylor P.R. (2001)
    570. Analysis of the EPHX1 113 polymorphism and GSTM1 homozygous null polymorphism and oral clefting associated with maternal smoking. (PubMed id 11471167)1, 4 Hartsfield J.K....Finnell R.A. (2001)
    571. Glutathione S-transferase M1 and T1 null genotypes and the risk of gastric and colorectal cancers. (PubMed id 11410321)1, 4 Saadat I. and Saadat M. (2001)
    572. Polymorphisms and colorectal tumor risk. (PubMed id 11487538)1, 4 Houlston R.S. and Tomlinson I.P. (2001)
    573. Increased risk for acute myeloid leukaemia in individuals with glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) gene defects. (PubMed id 11488937)1, 4 Arruda V.R....Costa F.F. (2001)
    574. Association of CYP1B1 codon 432 mutant allele in head and neck squamous cell cancer is reflected by somatic mutations of p53 in tumor tissue. (PubMed id 11389067)1, 4 Ko Y....Bruning T. (2001)
    575. Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration. (PubMed id 11124296)1, 4 Kimura K....Ohba N. (2000)
    576. Associations of plasma aflatoxin B1-albumin adduct level with plasma selenium level and genetic polymorphisms of glutathione S-transferase M1 and T1. (PubMed id 11525595)1, 4 Chen S.Y....Santella R.M. (2000)
    577. Increased prevalence of GSTM(1) null genotype in patients with myelodysplastic syndrome: a case-control study. (PubMed id 11279306)1, 4 Tsabouri S.E....Bourantas K.L. (2000)
    578. CYP1A1, GSTM1, and GSTP1 genetic polymorphisms and urinary 1-hydroxypyrene excretion in non-occupationally exposed individuals. (PubMed id 11045797)1, 4 Nerurkar P.V....Le Marchand L. (2000)
    579. Genetic polymorphisms of biotransformation enzymes: allele frequencies in the population of the Czech Republic. (PubMed id 11191882)1, 4 Sarmanova J....Soucek P. (2000)
    580. Identification of cytochrome P450 1A1 in human brain. (PubMed id 9500998)1, 2 Yun C.H.... Kim H.K. (1998)
    581. A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility. (PubMed id 8895751)1, 2 Cascorbi I.... Roots I. (1996)
    582. Genetic linkage of lung cancer-associated MspI polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P450IA1 gene. (PubMed id 1722803)1, 2 Hayashi S.... Kawajiri K. (1991)
    583. Structure and drug inducibility of the human cytochrome P-450c gene. (PubMed id 3019683)1, 2 Kawajiri K....Fujii-Kuriyama Y. (1986)
    584. Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6. (PubMed id 3000715)1, 2 Quattrochi L.C.... Tukey R.H. (1985)
    585. Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism. (PubMed id 2989797)1, 2 Jaiswal A.K.... Nebert D.W. (1985)
    586. Human dioxin-inducible cytochrome P1-450: complementary DNA and amino acid sequence. (PubMed id 3838385)1, 2 Jaiswal A.K.... Nebert D.W. (1985)
    587. Expression of CYP1A1 and CYP1B1 in human endothelial cells: regulation by fluid shear stress. (PubMed id 19126602)1, 9 Conway D.E....McIntire L.V. (2009)
    588. Regulation of the CYP1A1 gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin but not by beta-naphthoflavone or 3-methylcholanthrene is altered in hepatitis C virus replicon-expressing cells. (PubMed id 16788090)1, 9 Anderson G.R....Quattrochi L.C. (2006)
    589. Serum increases CYP1A1 induction by 3-methylcholanthrene. (PubMed id 12237110)1, 9 N'Guyen Q.B....Barra Y. (2002)
    590. Constitutive androstane receptor transcriptionally ac tivates human CYP1A1 and CYP1A2 genes through a common regulatory element in th e 5'-flanking region. (PubMed id 19682433)1, 9 Yoshinari K....Yamazoe Y. (2010)
    591. Aryl hydrocarbon receptor mediates laminar fluid shear stress-induced CYP1A1 activation and cell cycle arrest in vascular endothelial cells. (PubMed id 18065768)1, 9 Han Z....Sasaguri T. (2008)
    592. Benzo[a]pyrene induces apoptosis in RL95-2 human endometrial cancer cells by cytochrome P450 1A1 activation. (PubMed id 17640999)1, 9 Kim J.Y....Kim J.M. (2007)
    593. A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes. (PubMed id 16505155)1, 9 Ueda R....Yamazoe Y. (2006)
    594. Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: differential regulation in primary human hepatocytes versus transformed human cells. (PubMed id 16426572)1, 9 Zhang Z.Y....Littlefield B.A. (2006)
    595. Dietary ellagic acid inhibits the enzymatic activity of CYP1A1 without altering hepatic concentrations of CYP1A1 or CYP1A1 mRNA. (PubMed id 8024593)7, 9 Barch D.H....Pillay N.S. (1994)
    596. Regulation of cytochrome P4501A1 expression by hyperoxia in human lung cell lines: Implications for hyperoxic lung injury. (PubMed id 18824009)1, 9 Bhakta K.Y....Moorthy B. (2008)
    597. CYP1B1, but not CYP1A1, is downregulated by promoter methylation in colorectal cancers. (PubMed id 19287966)1, 9 Habano W....Ozawa S. (2009)
    598. Internal genomic sequence of human CYP1A1 gene is involved in superinduction of dioxin-induced CYP1A1 transcription by cycloheximide. (PubMed id 17316563)1, 9 Sakata Y....Ohsako S. (2007)
    599. Comparative homology modeling of human cytochrome P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin O-deethylation by site-directed mutagenesis and enzyme kinetic analysis. (PubMed id 17959138)1, 9 Lewis B.C....Miners J.O. (2007)
    600. Effects of genetic polymorphisms of CYP1A1, CYP2E1, G STM1, and GSTT1 on the urinary levels of 1-hydroxypyrene and 2-naphthol in airc raft maintenance workers. (PubMed id 11641039)1, 9 Lee C.Y....Kim H. (2001)
    601. Influence of polymorphism at p53, CYP1A1 and GSTM1 loci on p53 mutation and association of p53 mutation with prognosis in lung cancer. (PubMed id 10418172)4, 9 Wang Y.C....Lin P. (1999)
    602. Point-mutational MspI and Ile-Val polymorphisms closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish study population. (PubMed id 1284589)4, 9 Hirvonen A....Vainio H. (1992)
    603. CYP1A1 and CYP1A2 expression: comparing 'humanized' mouse lines and wild-type mice; comparing human and mouse hepatoma-derived cell lines. (PubMed id 19285097)1, 9 Uno S....Nebert D.W. (2009)
    604. CYP2D6 and CYP1A1 mutations in the Turkish population. (PubMed id 15648054)1, 9 Aydin M....Ozbek U. (2005)
    605. [Study on the relationship between polymorphisms of Cyp1A1, GSTM1, GSTT1 genes and the susceptibility to acute leukemia in the general population of Hunan province] (PubMed id 16676594)1, 9 Liu Q.X....Liu J. (2005)
    606. Polychlorinated biphenyls, cytochrome P450 1A1, and breast cancer risk in the Nurses' Health Study. (PubMed id 12496044)1, 9 Laden F....Kelsey K.T. (2002)
    607. Susceptibility to lung cancer in light smokers associated with CYP1A1 polymorphisms in Mexican- and African-Americans. (PubMed id 9419406)4, 9 Ishibe N....Kelsey K.T. (1997)
    608. Chlorzoxazone metabolism by porcine cytochrome P450 e nzymes and the effect of cytochrome b5. (PubMed id 20164110)7, 9 Wiercinska P. and Squires E.J. (2010)
    609. CYP1A2*1C, CYP2E1*5B, and GSTM1 polymorphisms are pre dictors of risk and poor outcome in head and neck squamous cell carcinoma patie nts. (PubMed id 19442564)4, 9 Olivieri E.H....Rogatto S.R. (2009)
    610. Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites. (PubMed id 17919675)1, 9 Spink D.C....Kaminsky L.S. (2008)
    611. The metabolism of amiodarone by various CYP isoenzymes of human and rat, and the inhibitory influence of ketoconazole. (PubMed id 18445370)7, 9 Elsherbiny M.E....Brocks D.R. (2008)
    612. Lack of association of GSTT1, GSTM1, GSTO1, GSTP1 and CYP1A1 polymorphisms for susceptibility and outcome in Brazilian prostate cancer patients. (PubMed id 18647550)4, 9 Lima M.M....Ward L.S. (2008)
    613. Osteopontin: a rapid and sensitive response to dioxin exposure in the osteoblastic cell line UMR-106. (PubMed id 16414014)1, 9 Wejheden C....Lind P.M. (2006)
    614. Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1. (PubMed id 16882880)1, 9 Martinez-Jimenez C.P....Jover R. (2006)
    615. Influence of genetic polymorphisms of CYP1A1 and GSTM1 on the urinary levels of 1-hydroxypyrene. (PubMed id 12919721)1, 9 Apostoli P....Berthou F. (2003)
    616. Flavonoids inhibit genetic toxicity produced by carcinogens in cells expressing CYP1A2 and CYP1A1. (PubMed id 11752233)1, 9 Lautraite S....Chipman J.K. (2002)
    617. Induction of cytochromes P450 1A1 and 1B1 in human lung adenocarcinoma CL5 cells by frying-meat emission particulate. (PubMed id 11955671)1, 9 Wang H.W....Ueng T.H. (2002)
    618. Polymorphisms of the CYP1A1 and GSTM1 gene involved in oral squamous cell carcinoma in association with a cigarette dose. (PubMed id 10435155)4, 9 Tanimoto K....Ichikawa T. (1999)
    619. Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility. (PubMed id 10026993)4, 9 Hengstler J.G....Oesch F. (1998)
    620. Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population. (PubMed id 8319207)4, 9 Nakachi K....Kawajiri K. (1993)
    621. Polymorphism in CYP1A1 and CYP2D6 genes: possible association with susceptibility to lung cancer. (PubMed id 7908263)4, 9 Hirvonen A....Vainio H. (1993)
    622. Human CYP1A1 (cytochrome P(1)450) gene: lack of association between the Msp I restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population. (PubMed id 1726950)4, 9 Tefre T....Borresen A.L. (1991)
    623. Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution. (PubMed id 19800896)4, 9 Rubes J....Sram R.J. (2010)
    624. Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells. (PubMed id 19013013)1, 9 Anwar-Mohamed A. and El-Kadi A.O. (2009)
    625. Investigations of the posttranslational mechanism of arsenite-mediated downregulation of human cytochrome P4501A1 levels: the role o f heme oxygenase-1. (PubMed id 19526463)1, 9 Bessette E.E....Kaminsky L.S. (2009)
    626. Common genetic variations of the cytochrome P450 1A1 gene and risk of hepatocellular carcinoma in a Chinese population. (PubMed id 19110417)1, 9 Li R....Jin L. (2009)
    627. Association of CYP1A1*2A polymorphism with male infer tility in Indian population. (PubMed id 19786002)1, 9 Vani G.T....Pardhanandana Reddy P. (2009)
    628. Quantification of phase I/II metabolizing enzyme gene expression and polycyclic aromatic hydrocarbon-DNA adduct levels in human prostate. (PubMed id 19143007)1, 9 John K....Martin F.L. (2009)
    629. Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes. (PubMed id 19219744)1, 9 Laine J.E....Juvonen R.O. (2009)
    630. CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells-comparison with other conazole pesticides. (PubMed id 19070657)1, 9 Sergent T....Schneider Y.J. (2009)
    631. Anticancer effects of the flavonoid diosmetin on cell cycle progression and proliferation of MDA-MB 468 breast cancer cells due to CYP1 activation. (PubMed id 19424633)1, 9 Androutsopoulos V.P....Potter G. (2009)
    632. CYP1-mediated antiproliferative activity of dietary f lavonoids in MDA-MB-468 breast cancer cells. (PubMed id 19666078)1, 9 Androutsopoulos V.P....Spandidos D.A. (2009)
    633. UVR exposure sensitizes keratinocytes to DNA adduct f ormation. (PubMed id 19789301)1, 9 Nair S....Dannenberg A.J. (2009)
    634. [Study on the association of cytochrome P450 polymorp hisms and the risk of esophageal cancer: a meta-analysis.] (PubMed id 20193595)1, 9 Dai L.P....LA1 Q.J. (2009)
    635. Elevated expression of CYP1A1 and gamma-SYNUCLEIN in human ectopic (ovarian) endometriosis compared with eutopic endometrium. (PubMed id 18849443)1, 9 Singh M.N....Martin F.L. (2008)
    636. PAH-DNA adducts in a Chinese population: relationship to PAH exposure, smoking and polymorphisms of metabolic and DNA repair genes. (PubMed id 17896209)1, 9 Hu Y....Qu Q. (2008)
    637. The effect of indole-3-carbinol on the expression of CYP1A1, CYP1B1 and AhR genes and proliferation of MCF-7 cells. (PubMed id 17311112)1, 9 Ociepa-Zawal M....Trzeciak W.H. (2007)
    638. An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites. (PubMed id 17630984)1, 9 Kommaddi R.P....Ravindranath V. (2007)
    639. Genetic susceptibility to environmental carcinogenesis in Slovenian melanoma patients. (PubMed id 16998606)1, 9 Dolzan V....Breskvar K. (2006)
    640. Role of adrenoceptor-linked signaling pathways in the regulation of CYP1A1 gene expression. (PubMed id 15627480)7, 9 Konstandi M....Lang M.A. (2005)
    641. [Genetic polymorphisms of the CYP450 1A1, CYP450 2E1, GSTM1, GSTT1, and GSTP1 in Korean] (PubMed id 15952134)1, 9 Xu Q.S....Lee K.H. (2005)
    642. CYP3A4 is a vitamin D-24- and 25-hydroxylase: analysis of structure function by site-directed mutagenesis. (PubMed id 15546903)1, 9 Gupta R.P....Bell N.H. (2005)
    643. Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells: alternative subcellular enzyme compartmentation may contribute to carcinogenesis. (PubMed id 15867368)1, 9 Leung Y.K.... Ho S.M. (2005)
    644. Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites. (PubMed id 15521013)1, 9 Seree E....Barra Y. (2004)
    645. Frequent CYP1A1 expression in gastric cancers and their related lesions. (PubMed id 15547760)1, 9 Zhang K.L....Li H. (2004)
    646. Variable drug metabolism genes in Arab population. (PubMed id 15111988)1, 9 Bu R....Bhatia K. (2004)
    647. Involvement of cytochrome P450 1A2 in the biotransformation of trans-resveratrol in human liver microsomes. (PubMed id 15276085)7, 9 Piver B....Lucas D. (2004)
    648. Blockage of multidrug resistance-associated proteins potentiates the inhibitory effects of arsenic trioxide on CYP1A1 induction by polycyclic aromatic hydrocarbons. (PubMed id 12490585)1, 9 Vernhet L....Fardel O. (2003)
    649. Methylation of cytochrome P4501A1 promoter in the lung is associated with tobacco smoking. (PubMed id 14695173)1, 9 Anttila S....Nurminen T. (2003)
    650. Molecular modeling of cytochrome P450 1A1: enzyme-substrate interactions and substrate binding affinities. (PubMed id 12354067)1, 9 Szklarz G.D. and Paulsen M.D. (2002)
    651. Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone. (PubMed id 12147246)1, 9 Ishida S....Sawada J. (2002)
    652. Genetic polymorphism of cytochrome P450 1A1 (Cyp1A1) and glutathione transferases (M1, T1 and P1) among Africans. (PubMed id 12435115)1, 9 Dandara C....Hasler J.A. (2002)
    653. Differentiation-dependent induction of CYP1A1 in cultured rat small intestinal epithelial cells, colonocytes, and human colon carcinoma cells: basement membrane-mediated apoptosis. (PubMed id 12210751)1, 9 Sterling K.M. and Cutroneo K.R. (2002)
    654. CYP1A1*2 and CYP1A1*3 polymorphisms cosegregate in the Indian population. (PubMed id 12378791)1, 9 Kotekar A. and Bhisey R. (2002)
    655. Epoxidation of benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 in reconstituted membranes. Effects of charge and nonbilayer phase propensity of the membrane. (PubMed id 11952781)1, 9 Kisselev P....Roots I. (2002)
    656. Human aryl hydrocarbon receptor polymorphisms that result in loss of CYP1A1 induction. (PubMed id 11689007)1, 9 Wong J.M.Y.... Harper P.A. (2001)
    657. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. (PubMed id 11714871)7, 9 Chang T.K....Lee W.B. (2001)
    658. Polymorphisms of the xenobiotic-metabolizing enzymes CYP1A1 and NAT-2 in systemic sclerosis and lupus erythematosus. (PubMed id 10599336)4, 9 von Schmiedeberg S....Gleichmann E. (1999)
    659. Toluene metabolism by cDNA-expressed human hepatic cytochrome P450. (PubMed id 9065730)7, 9 Nakajima T....Aoyama T. (1997)
    660. Induction of CYP1A1 by GABA receptor ligands. (PubMed id 8954111)7, 9 Sadar M.D....Andersson T.B. (1996)
    661. [Association of cytochrome P-450 1A1 (CYP1A1) gene polymorphism to smoking status and hematologic findings] (PubMed id 8672811)4, 9 Shinozaki S....Asaka A. (1996)
    662. A CYP1A1 restriction fragment length polymorphism is associated with breast cancer in African-American women. (PubMed id 7641189)4, 9 Taioli E....Garte S.J. (1995)
    663. Association of cigarette smoking and CYP1A1 polymorphisms with adenocarcinoma of the lung by grades of differentiation. (PubMed id 7554077)4, 9 Nakachi K....Imai K. (1995)
    664. Genetics of CYP1A1: coamplification of specific alleles by polymerase chain reaction and association with breast cancer. (PubMed id 8000303)4, 9 Rebbeck T.R....Buetow K.H. (1994)
    665. Genetic polymorphisms of NQO1, CYP1A1 and TPMT and sus ceptibility to acute lymphoblastic leukemia in a Tunisian population. (PubMed id 23065291)1 Ouerhani S....Abbes S. (2013)
    666. Aryl hydrocarbon receptor repressor (AhRR) function re visited: repression of CYP1 activity in human skin fibroblasts is not related to AhRR expression. (PubMed id 22951721)1 Tigges J....Fritsche E. (2013)
    667. Lung cancer risk in relation to nicotinic acetylcholin e receptor, CYP2A6 and CYP1A1 genotypes in the Bangladeshi population. (PubMed id 23178447)1 Islam M.S....Hasnat A. (2013)
    668. Cytochrome P4501A1 genotypes and smoking- and hyperten sion-related ischemic stroke risk. (PubMed id 23111888)1 Demirdogen B.C....Adali O. (2013)
    669. Antitumor activity of a duocarmycin analogue rationali zed to be metabolically activated by cytochrome P450 1A1 in human transitional c ell carcinoma of the bladder. (PubMed id 23033491)1 Sutherland M....Patterson L.H. (2013)
    670. Beta-catenin signaling induces CYP1A1 expression by di srupting adherens junctions in Caco-2 human colon carcinoma cells. (PubMed id 23174221)1 Kasai S....Kikuchi H. (2013)
    671. Quantitative synthesis of the association between the cytochrome P450 1A1 Ile462Val polymorphism and prostate cancer risk. (PubMed id 23381648)1 Han G....Zhu F. (2013)
    672. Pelargonidin activates the AhR and induces CYP1A1 in p rimary human hepatocytes and human cancer cell lines HepG2 and LS174T. (PubMed id 23419638)1 Kamenickova A....Dvorak Z. (2013)
    673. CYP1A1 MspI polymorphism is associated with prostate c ancer susceptibility: evidence from a meta-analysis. (PubMed id 23475304)1 Ding G....Liao Z. (2013)
    674. Influence of CYP1A1/CYP1A2 and AHR polymorphisms on sy stemic olanzapine exposure. (PubMed id 23492908)1 Soderberg M.M....Dahl M.L. (2013)
    675. Significant association between CYP1A1 T3801C polymorp hism and cervical neoplasia risk: a systematic review and meta-analysis. (PubMed id 23055196)1 Xia L....Wu K. (2013)
    676. CYP1AI and CYP2E1 gene polymorphisms may increase susc eptibility to oral submucous fibrosis among betel quid chewers of eastern India. (PubMed id 23124075)1 Chaudhuri S.R....Chaudhuri K. (2013)
    677. Association of gene polymorphism in detoxification enz ymes and urinary 8-OHdG levels in traffic policemen exposed to vehicular exhaust . (PubMed id 23293967)1 Prasad S.B....Prasad H.M. (2013)
    678. Genetic association of aromatic hydrocarbon receptor ( AHR) and cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) polymorp hisms with dioxin blood concentrations among pregnant Japanese women. (PubMed id 23528250)1 Kobayashi S....Kishi R. (2013)
    679. Cytochrome P450 1A1 (CYP1A1) gene polymorphisms and ov arian cancer risk: a meta-analysis. (PubMed id 22733497)1 Sergentanis T.N....Vlahos N.F. (2012)
    680. Breast cancer risk, fungicide exposure and CYP1A1*2A g ene-environment interactions in a province-wide case control study in Prince Edw ard Island, Canada. (PubMed id 22754477)1 Ashley-Martin J....Guernsey J.R. (2012)
    681. Genetic polymorphism of estrogen metabolizing enzymes in Siberian women with breast cancer. (PubMed id 21977969)1 Khvostova E.P....Gulyaeva L.F. (2012)
    682. Analysis of GSTM1, GSTT1, and CYP1A1 in idiopathic mal e infertility. (PubMed id 21775774)1 Salehi Z....Madani A.H. (2012)
    683. Validation of PCR-RFLP techniques for the evaluation o f codon 72 of p53 and CYP1A1 gene's polymorphisms in relation with ovarian cance r in a Romanian population. (PubMed id 22395499)1 Matei M.C....Azoicai D. (2012)
    684. CYP1A1 is a target of miR-892a-mediated post-transcrip tional repression. (PubMed id 22470100)1 Choi Y.M....Bae S. (2012)
    685. Quercetin, quercetin glycosides and taxifolin differ i n their ability to induce AhR activation and CYP1A1 expression in HepG2 cells. (PubMed id 22422552)1 Vrba J....Ulrichova J. (2012)
    686. Risk factor for clear cell renal cell carcinoma in Chi nese population: a case-control study. (PubMed id 22000673)1 Wang G....Cao G. (2012)
    687. Down-regulation of CYP1A1 expression in breast cancer. (PubMed id 22901117)1 Hafeez S....Kayani M.A. (2012)
    688. CYP1A1 Ile462Val polymorphism and cervical cancer: evi dence from a meta-analysis. (PubMed id 22948778)1 Yang S....Han S. (2012)
    689. The effect of CYP1A1, GSTT1 and GSTM1 polymorphisms on the risk of lung cancer: a case-control study. (PubMed id 22893352)1 Atinkaya C....Sunguroglu A. (2012)
    690. The relationship among IL-13, GSTP1, and CYP1A1 polymo rphisms and environmental tobacco smoke in a population of children with asthma in Northern Mexico. (PubMed id 22236719)1 Munoz B....Albores A. (2012)
    691. Lack of association of CYP1A1-MspI SNP and GSTM1 null genotypes with cancer in a Brazilian family with unusually high cancer incidence . (PubMed id 22782580)1 Moraes L.N....Souza I.L. (2012)
    692. Does cytochrome P450 1A1 MspI polymorphism increase ac ute lymphoblastic leukemia risk? Evidence from 2013 cases and 2903 controls. (PubMed id 22964275)1 Zhuo W....Chen Z. (2012)
    693. Association between CYP1A1 Ile462Val variation and acu te leukemia risk: meta-analyses including 2164 cases and 4160 controls. (PubMed id 23056546)1 Zhuo W....Chen Z. (2012)
    694. Common polymorphisms in CYP1A1, GSTM1, GSTT1, GSTP1 an d XPD genes and endogenous DNA damage. (PubMed id 22183307)1 Wlodarczyk M. and Nowicka G. (2012)
    695. Interactions between CYP1A1 polymorphisms and cigarett e smoking are associated with the risk of hepatocellular carcinoma: evidence fro m epidemiological studies. (PubMed id 22297691)1 Yu L....Zhu L.Y. (2012)
    696. Carnosol, a constituent of Zyflamend, inhibits aryl hy drocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and mu tagenesis. (PubMed id 22374940)1 Mohebati A....Dannenberg A.J. (2012)
    697. Quantitative assessment of CYP1A1*2A variations with o ral carcinoma susceptibility: evidence from 1,438 cases and 2,086 controls. (PubMed id 22909097)1 Zhuo X....Tan Y. (2012)
    698. Cytochrome P450 1A1 (CYP1A1) gene polymorphisms and ce rvical cancer risk: a meta-analysis. (PubMed id 22294106)1 Sergentanis T.N....Vlahos N.F. (2012)
    699. TLR2 controls intestinal carcinogen detoxication by CY P1A1. (PubMed id 22442665)1 Do K.N....Parlesak A. (2012)
    700. Risk modification by CYP1A1 and GSTM1 polymorphisms in the association of cigarette smoking and systemic lupus erythematosus in a Japa nese population. (PubMed id 22217397)1 Kiyohara C....Tada Y. (2012)
    701. CYP1A1 Ile462Val polymorphism contributes to lung canc er susceptibility among lung squamous carcinoma and smokers: a meta-analysis. (PubMed id 22952673)1 Ji Y.N....Suo L.J. (2012)
    702. CYP1A1 MspI polymorphisms and lung cancer risk: an upd ated meta-analysis involving 20,209 subjects. (PubMed id 22579698)1 Ji Y.N....Suo L.J. (2012)
    703. Lack of association between the CYP1A1 Ile462Val polym orphism and endometrial cancer risk: a meta-analysis. (PubMed id 23098461)1 Wang X.W....Liu Q.Y. (2012)
    704. Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism. (PubMed id 22949628)1 Huang Q....Szklarz G.D. (2012)
    705. Role of CYP1A1 haplotypes in modulating susceptibility to coronary artery disease. (PubMed id 23259321)1 Lakshmi S.V....Kutala V.K. (2012)
    706. Association of CYP1A1, GSTM1, and GSTT1 gene polymorph ism with risk of oral submucous fibrosis in a section of North Indian population . (PubMed id 22752755)1 Ghosh T....Agrawal D. (2012)
    707. [Effects of CYP1A1 and GSTM1 gene polymorphisms and BP DE-DNA adducts on lung cancer]. (PubMed id 22311486)1 Chen C.M....Sun X.Y. (2012)
    708. Quantitative assessment of the associations between CY P1A1 polymorphisms and gastric cancer risk. (PubMed id 22359202)1 Guo R. and Guo X. (2012)
    709. CYP1A1 Ile462Val is a risk factor for ovarian cancer d evelopment. (PubMed id 22277800)1 Huang M....Liu C. (2012)
    710. Impact of genetic variations of the CYP1A1, GSTT1, and GSTM1 genes on the risk of coronary artery disease. (PubMed id 21848428)1 Taspinar M....Sunguroglu A. (2012)
    711. Theoretical investigation of differences in nitroreduc tion of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1. (PubMed id 23353840)1 Jerabek P....Stiborova M. (2012)
    712. Effects of cytochrome P450 1A1 and uridine-diphosphate -glucuronosyltransferase 1A1 allelic polymorphisms on the risk of development an d the prognosis of head and neck cancers. (PubMed id 22273851)1 Szanyi I....Kiss I. (2012)
    713. Bioactivation versus detoxication of the urothelial ca rcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2. (PubMed id 22086975)1 Stiborova M....Arlt V.M. (2012)
    714. CYP1A1 protein activity is associated with allelic var iation in pterygium tissues and cells. (PubMed id 22876118)1 Peng M.L....Cheng Y.W. (2012)
    715. Association of CYP1A1 polymorphisms with prostate canc er risk: an updated meta-analysis. (PubMed id 23065259)1 Li H....He T. (2012)
    716. Associations between polymorphisms in the AHR and CYP1 A1-CYP1A2 gene regions and habitual caffeine consumption. (PubMed id 22854411)1 Josse A.R....El-Sohemy A. (2012)
    717. Cytochrome 1A1 and 1B1 gene diversity in the Zanzibar islands. (PubMed id 22594779)1 Cavaco I....Gil J.P. (2012)
    718. CYP1A1 gene polymorphisms: modulator of genetic damage in coal-tar workers. (PubMed id 22994769)1 Giri S.K....Gautam S.K. (2012)
    719. Interaction between maternal passive smoking during pr egnancy and CYP1A1 and GSTs polymorphisms on spontaneous preterm delivery. (PubMed id 23152866)1 Luo Y.J....Chen W.Q. (2012)
    720. [Association between genetic polymorphism of metaboliz ing enzymes and DNA repairing enzymes and the susceptibility of lung cancer in H enan population]. (PubMed id 22611936)1 Wang N....Wu Y. (2012)
    721. Inhibition of cytochrome P4501-dependent clearance of the endogenous agonist FICZ as a mechanism for activation of the aryl hydrocarbo n receptor. (PubMed id 22392998)1 Wincent E....Rannug A. (2012)
    722. Polymorphisms of the CYP1A1 and CYP2E1 genes in head a nd neck squamous cell carcinoma risk. (PubMed id 21590276)1 Cury N.M....Goloni-Bertollo E.M. (2012)
    723. Meta-analysis of the association of CYP1A1 polymorphis ms with gastric cancer susceptibility and interaction with tobacco smoking. (PubMed id 22707145)1 Han F....Li W. (2012)
    724. Vitamin D receptor activation enhances benzo[a]pyrene metabolism via CYP1A1 expression in macrophages. (PubMed id 22837390)1 Matsunawa M....Makishima M. (2012)
    725. [LOH and genetic polymorphysms of breast cancer]. (PubMed id 23350368)1 Utsumi T. (2012)
    726. Associations between CYP1A1 and CYP2E1 polymorphisms a nd susceptibility to esophageal cancer in Chaoshan and Taihang areas of China. (PubMed id 22088806)1 Wang D....Zhang J. (2012)
    727. Genetic polymorphisms in CYP1A1, GSTM1, GSTP1 and GSTT 1 metabolic genes and risk of lung cancer in Asturias. (PubMed id 23013535)1 Lopez-Cima M.F....Tardon A. (2012)
    728. CYP1A1 MspI polymorphism and acute myeloid leukemia ri sk: meta-analyses based on 5018 subjects. (PubMed id 22846179)1 Zhuo W....Chen Z. (2012)
    729. [Association of polymorph variants of CYP1A2 and CYP1A 1 genes with reproductive and thyroid diseases in female workers of petrochemica l industry]. (PubMed id 22855999)1 Irmiakova A.R....Viktorova T.V. (2012)
    730. DNA methylation of the CYP1A1 enhancer is associated w ith smoking-induced genetic alterations in human lung. (PubMed id 22213191)1 Tekpli X....Mollerup S. (2012)
    731. Association between CYP1A1 polymorphism and colorectal cancer risk: a meta-analysis. (PubMed id 21710246)1 Zheng Y....Li H.L. (2012)
    732. CYP1AI, glutathione S-transferase gene polymorphisms a nd risk of Polycythemia vera. (PubMed id 22018952)1 Naffa R.G....Ismail S.I. (2012)
    733. Polymorphisms in GSTM1, CYP1A1, CYP2E1, and CYP2D6 are associated with susceptibility and chemotherapy response in non-small-cell lung cancer patients. (PubMed id 22109568)1 Li W....Gu M. (2012)
    734. [Chronic inflammatory and dystrophic diseases of the e ye anterior segment and their association with genetic polymorphisms in workers of metallurgic industry]. (PubMed id 22997752)1 Mel'nichenko M.A....Zabelin V.I. (2012)
    735. Lack of association of CYP1A1 polymorphism with prosta te cancer susceptibility of Tunisian men. (PubMed id 22304463)1 Souiden Y....Mahdouani K. (2012)
    736. Maternal obesity alters feto-placental cytochrome P450 1A1 activity. (PubMed id 23046808)1 DuBois B.N....Cherala G. (2012)
    737. Cytochrome P450 1A1 Ile462Val polymorphism and oral ca rcinoma risk: an updated meta-analysis including 1,515 cases and 2,233 controls. (PubMed id 22847262)1 Zhuo X....Tan Y. (2012)
    738. Identification of human cytochrome P450 and flavin-con taining monooxygenase enzymes involved in the metabolism of lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist. (PubMed id 22266842)7 Usmani K.A....Sadeque A.J. (2012)
    739. Polymorphisms in CYP1A1 and ethnic-specific susceptib ility to acute lymphoblastic leukemia in children. (PubMed id 21586621)1 Swinney R.M....Tomlinson G.E. (2011)
    740. [The role of mutation of gene cyp1A1 and benzapilene i n cytogenetic changes of urinary tract epitheliocytes in oil industry workers em ployed in the oil fields of the North of West Siberia]. (PubMed id 22448487)1 Il'inskikh N.N....Iamkovaia E.V. (2011)
    741. Induction of cytochromes P450 1A1 and 1A2 by tanshino nes in human HepG2 hepatoma cell line. (PubMed id 21262253)1 Zhang R....Wang G. (2011)
    742. CYP1A1 polymorphism in adolescents with polycystic ov ary syndrome. (PubMed id 20965504)1 AkgA1l S....AktaA9 D. (2011)
    743. Inhibition of 17I^-estradiol activation by CYP1A1: gen otype- and regioselective inhibition by St. John's Wort and several natural pol yphenols. (PubMed id 20883830)1 Schwarz D....Roots I. (2011)
    744. [CYP1A1 gene and GSTM1 gene polymorphism and the comb ined effects and risk of lung cancer: a meta-analysis]. (PubMed id 21859547)1 Li C....Zhou B. (2011)
    745. [Genetic study of predisposition to community-acquired pneumonia]. (PubMed id 22312901)1 Moroz V.V....Rubanovich A.V. (2011)
    746. Modulation of CYP1A1 activity by a Ginkgo biloba extr act in the human intestinal Caco-2 cells. (PubMed id 21329749)1 Ribonnet L....Larondelle Y. (2011)
    747. Polymorphisms of the CYP1A1, CYP2E1 and XRCC1 genes a nd cancer risk in a Southern Italian population: a case-control study. (PubMed id 21508386)1 Bianchino G....Sgambato A. (2011)
    748. Effect of CYP1A1 MSPI polymorphism on the relationship between TP53 mutation and CDKN2A hypermethylation in non-small cell lung cancer . (PubMed id 22154617)1 Tan C....Jin Y.T. (2011)
    749. CYP1A1, GSTM1 and GSTT1 polymorphisms, tobacco and al cohol status and risk of head and neck squamous cell carcinoma. (PubMed id 21870186)1 LourenAso G.J....Lima C.S. (2011)
    750. CYP1A1 gene polymorphisms: lack of association with br east cancer susceptibility in the southern region (Madurai) of India. (PubMed id 22292665)1 Kiruthiga P.V....Devi K.P. (2011)
    751. Importance of CYP1A1 polymorphism and its transcriptio nal regulation in ovarian and endometrial cancer. (PubMed id 22384629)1 Mrozikiewicz P.M....Drews K. (2011)
    752. [Study of cytochrome P450 1A1 gene 3'-UTR 6235T-C pol ymorphism and susceptibility to breast cancer with Uighur medicine]. (PubMed id 21418988)1 Tuerxun M....Dolikun M. (2011)
    753. Genetic variation in carcinogen metabolizing genes as sociated with oral cancer in pakistani population. (PubMed id 21545219)1 Masood N....Faryal R. (2011)
    754. Genetic variants in novel pathways influence blood pre ssure and cardiovascular disease risk. (PubMed id 21909115)1  ....Johnson T. (2011)
    755. Cytochrome P450 1A1 gene polymorphisms and endometria l cancer risk: a meta-analysis. (PubMed id 21270613)1 Sergentanis T.N....Vlahos N.F. (2011)
    756. Smoking, the xenobiotic pathway, and clubfoot. (PubMed id 21254355)1 Sommer A....Hecht J.T. (2011)
    757. A genome-wide association study in Europeans and Sout h Asians identifies five new loci for coronary artery disease. (PubMed id 21378988)4 (2011)
    758. CYP1A1 Ile462Val polymorphism and susceptibility to lu ng cancer: a meta-analysis based on 32 studies. (PubMed id 22025136)1 Wang J.J....Ma T.Y. (2011)
    759. Relationship between CYP1A1 genetic polymorphisms and renal cancer in China. (PubMed id 22296350)1 Chen J....Jiang C.B. (2011)
    760. Associations of xenobiotic-metabolizing enzyme genotyp es PON1Q192R, PON1L55M and CYP1A1*2A MspI with pathological symptoms of a rural population in south Greece. (PubMed id 21718208)1 Tsatsakis A.M....Koutis C. (2011)
    761. The effect of CYP1A1 and GSTM1 gene polymorphisms in bladder cancer development in a Turkish population. (PubMed id 21709011)1 A9ztA1rk T....A^sbir T. (2011)
    762. A remark about CYP1A1 Thr461Asn genotype frequencies in a recent endometrial cancer case-control study. (PubMed id 21130723)1 Economopoulos K.P. and Sergentanis T.N. (2011)
    763. Role of CYP1A1 (T6235C) polymorphism and cigarette sm oking in the development of coronary heart disease in Tunisian population. (PubMed id 21869479)1 Achour A....Zemni R. (2011)
    764. CYP1A1 Ile462Val polymorphism contributes to colorect al cancer risk: a meta-analysis. (PubMed id 21246002)1 Jin J.Q....Xia L.Y. (2011)
    765. CYP1A1, CYP2E1, and GSTM1 gene polymorphisms and susc eptibility to colorectal and gastric cancer among Lebanese. (PubMed id 21385088)1 Darazy M....Abdel-Razzak Z. (2011)
    766. Meta-analysis of cytochrome P4501A1 MspI gene polymorp hism and childhood acute leukemia. (PubMed id 22365406)1 Zhang Y.D....Hu Q. (2011)
    767. Expression of xenobiotic metabolizing genes in head a nd neck cancer tissues. (PubMed id 21545198)1 Masood N....Kayani M.A. (2011)
    768. Soy isoflavones, CYP1A1, CYP1B1, and COMT polymorphis ms, and breast cancer: a case-control study in southwestern China. (PubMed id 21438753)1 Wang Q....Huang Y. (2011)
    769. CYP1A1 induction in the colon by serum: involvement o f the PPARI+ pathway and evidence for a new specific human PPREI+ site. (PubMed id 21304969)1 Villard P.H....Seree E. (2011)
    770. The effect of CYP1A1 polymorphisms on the risk of lun g cancer: a global meta-analysis based on 71 case-control studies. (PubMed id 21402622)1 Chen Z....Chen Z. (2011)
    771. Influence of genetic polymorphisms on frequency of mi cronucleated buccal epithelial cells in leukoplakia patients. (PubMed id 20850372)1 Mahimkar M.B....Patil T. (2010)
    772. CYP2D6 mediates 4-hydroxylation of clonidine in vitro : implication for pregnancy-induced changes in clonidine clearance. (PubMed id 20570945)7 Claessens A.J....Hebert M.F. (2010)
    773. CYP1A1, smoking and venous thromboembolism. (PubMed id 20664892)1 Zhu J....Wang C. (2010)
    774. Evaluation of candidate genes for cholinesterase acti vity in farmworkers exposed to organophosphorus pesticides: association of sing le nucleotide polymorphisms in BCHE. (PubMed id 20529763)1 Howard T.D....Arcury T.A. (2010)
    775. [CYP1A1 polymorphisms, lack of glutathione S-transfer ase M1 (GSTM1), cooking oil fumes and lung cancer risk in non-smoking women]. (PubMed id 21211368)1 Zhu X.X....Gu Q.H. (2010)
    776. Evaluation of the influence of polymorphic variants C YP1A1*2B, CYP1B1*2, CYP3A4*1B, GSTM1*0, and GSTT1*0 in prostate cancer. (PubMed id 20884258)1 Rodrigues Syllos CA^lus I.M. (2010)
    777. Methylation patterns of genes coding for drug-metabol izing enzymes in tamoxifen-resistant breast cancer tissues. (PubMed id 20628863)1 Kim S.J....Ro J. (2010)
    778. In utero tobacco exposure epigenetically modifies pla cental CYP1A1 expression. (PubMed id 20462615)1 Suter M....Aagaard-Tillery K. (2010)
    779. Correlation of xenobiotic-metabolizing enzymes, oxida tive stress and NFkappaB signaling with histological grade and menopausal statu s in patients with adenocarcinoma of the breast. (PubMed id 19995559)1 Vinothini G. and Nagini S. (2010)
    780. A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiat ion in rectal cancer. (PubMed id 20644561)1 Ho-Pun-Cheung A....Lopez-Crapez E. (2010)
    781. Genetic polymorphisms in sex hormone metabolizing gene s and drug response in women with epilepsy. (PubMed id 21121773)4 Grover S....Kukreti R. (2010)
    782. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (2010)
    783. CYP1A2*1F and GSTM1 Alleles Are Associated with Susce ptibility to Porphyria Cutanea Tarda. (PubMed id 20957336)1 Wickliffe J.K....Anderson K.E. (2010)
    784. Microarray-based detection of CYP1A1, CYP2C9, CYP2C19 , CYP2D6, GSTT1, GSTM1, MTHFR, MTRR, NQO1, NAT2, HLA-DQA1, and AB0 allele frequ encies in native Russians. (PubMed id 20373852)1 Gra O....Nasedkina T. (2010)
    785. Errors and reproducibility of DNA array-based detecti on of allelic variants in ADME genes: PHARMAchip. (PubMed id 20136364)1 CuyA s la Torre R. (2010)
    786. An association between BPDE-like DNA adduct levels an d CYP1A1 and GSTM1 polymorphisma in pterygium. (PubMed id 20700368)1 Tung J.N....Cheng Y.W. (2010)
    787. Is genetic polymorphism of ER-alpha, CYP1A1, and CYP1 B1 a risk factor for uterine leiomyoma? (PubMed id 20559649)1 El-Shennawy G.A....El Behery M.M. (2010)
    788. SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. (PubMed id 19934256)7 Preissner S....Preissner R. (2010)
    789. Combined effects of serum trace metals and polymorphi sms of CYP1A1 or GSTM1 on non-small cell lung cancer: A hospital based case-con trol study in China. (PubMed id 20638923)1 Jin Y....Xu Y. (2010)
    790. Early life environment, neurodevelopment and the inte rrelation with atopy. (PubMed id 20701904)1 Sunyer J....Torrent M. (2010)
    791. CYP1A1, CYP3A5 and CYP3A7 polymorphisms and testicula r cancer susceptibility. (PubMed id 20345875)1 Kristiansen W....Aschim E.L. (2010)
    792. Toward personalized medicine in renal transplantation . (PubMed id 20970553)1 Lampreabe I....Olano-Martin E. (2010)
    793. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    794. The effects of pyridoxine deficiency and supplementat ion on hematological profiles, lymphocyte function, and hepatic cytochrome P450 in B6C3F1 mice. (PubMed id 19637937)7 Tangjarukij C....Ruchirawat M. (2009)
    795. Utility of Nicotiana tabacum cell suspension cultures expressing human CYP1A1, CYP1A2 and CYP3A4 to study the oxidative metabolism o f the herbicide 14C-fluometuron. (PubMed id 19356113)1 Breuer M.A....Schuphan I. (2009)
    796. Cytochrome P450 1A1, glutathione S-transferases M1 an d T1 polymorphisms in Ovambos and Mongolians. (PubMed id 19264525)1 Fujihara J....Takeshita H. (2009)
    797. Clinical pharmacokinetics of tyrosine kinase inhibito rs. (PubMed id 19733976)7 van Erp N.P....Guchelaar H.J. (2009)
    798. [Adverse birth outcomes of maternal smoking during pregnancy and genetic polymorphisms: exploiting gene-environment interaction]. (PubMed id 19797843)1 Sasaki S. and Kishi R. (2009)
    799. High risk of 'de novo' acute myeloid leukaemia in ind ividuals with cytochrome P450 A1 (CYP1A1) and NAD(P)H:quinone oxidoreductase 1 (NQO1) gene defects. (PubMed id 19456854)1 Yamaguti G.G....Lima C.S. (2009)
    800. Xenobiotic metabolizing gene variants, dietary heteroc yclic amine intake, and risk of prostate cancer. (PubMed id 19223546)4 Koutros S....Cross A.J. (2009)
    801. Dissimilar in vitro and in vivo effects of ellagic ac id and its microbiota-derived metabolites, urolithins, on the cytochrome P450 1 A1. (PubMed id 19469472)7 GonzA!lez-SarrA-as A....EspA-n J.C. (2009)
    802. Substrates, inducers, inhibitors and structure-activi ty relationships of human Cytochrome P450 2C9 and implications in drug developm ent. (PubMed id 19515014)7 Zhou S.F....Cai J.P. (2009)
    803. Identification of the human enzymes involved in the o xidative metabolism of dasatinib: an effective approach for determining metabol ite formation kinetics. (PubMed id 18556438)7 Wang L....Zhang D. (2008)
    804. Low organic solvent exposure and combined maternal-infant gene polymorphisms affect gestational age. (PubMed id 18070799)1 Qin X....Chen D. (2008)
    805. Involvement of CREM in CYP1A1 induction through ligand-independent activation pathway of aryl hydrocarbon receptor in HepG2 cells. (PubMed id 18700132)1 Sasamori E....Kikuchi H. (2008)
    806. Antipsychotic-induced tardive dyskinesia and polymorphic variations in COMT, DRD2, CYP1A2 and MnSOD genes: a meta-analysis of pharmacogenetic interactions. (PubMed id 18180754)1 Bakker P.R....van Os J. (2008)
    807. Heat shock protein 90 inhibitors suppress aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and DNA adduct formation. (PubMed id 19138996)1 Hughes D....Dannenberg A.J. (2008)
    808. Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition. (PubMed id 18493746)1 Westerink W.M....Schoonen W.G. (2008)
    809. A shuffled CYP1A library shows both structural integrity and functional diversity. (PubMed id 17823232)1 Johnston W.A....Gillam E.M. (2007)
    810. Genotype frequencies of polymorphic GSTM1, GSTT1, and cytochrome P450 CYP1A1 in Mexicans. (PubMed id 18078203)1 Montero R....Camacho-Carranza R. (2007)
    811. Using microarray analysis to evaluate genetic polymorphisms involved in the metabolism of environmental chemicals. (PubMed id 17642299)1 Ban S....Kishi R. (2007)
    812. Diversity of common alternative splicing variants of human cytochrome P450 1A1 and their association to carcinogenesis. (PubMed id 17549424)1 Bauer M....Grabsch C. (2007)
    813. Increased CYP1A1 expression in human exfoliated urothelial cells of cigarette smokers compared to non-smokers. (PubMed id 16947004)1 Dorrenhaus A....Roos P.H. (2007)
    814. CYP1A1 polymorphisms modify overall survival in acute myeloid leukemia patients. (PubMed id 17577786)1 Pelloso L.A....Chauffaille M.d.e. . . . . . . . . . . .L. (2007)
    815. Urinary 1-hydroxypyrene level relative to vehicle exhaust exposure mediated by metabolic enzyme polymorphisms. (PubMed id 17429172)1 Chuang C.Y. and Chang C.C. (2007)
    816. Differential metabolism of gefitinib and erlotinib by human cytochrome P450 enzymes. (PubMed id 17575239)7 Li J....Baker S.D. (2007)
    817. Recalling P446. P4501A1 (CYP1A1) opting for clinical application. (PubMed id 17786624)1 Hildebrandt A.G....Roots I. (2007)
    818. Differential effect of over-expressing UGT1A1 and CYP1A1 on xenobiotic assault in MCF-7 cells. (PubMed id 17981384)1 Leung H.Y....Leung L.K. (2007)
    819. Is the natural PCDD/PCDF mixture toxic for human placental JEG-3 cell line? The action of the toxicants on hormonal profile, CYP1A1 activity, DNA damage and cell apoptosis. (PubMed id 17623765)1 Augustowska K....Gregoraszczuk E.L. (2007)
    820. Interactive effects between CYP1A1 genotypes and environmental polychlorinated dibenzo-p-dioxins and dibenzofurans exposures on liver function profile. (PubMed id 16407087)1 Chen H.L....Lee C.C. (2006)
    821. The absence of interaction between drug metabolizing enzyme genotypes and maternal lifestyle factors on glycophorin A somatic mutation frequency levels in newborns. (PubMed id 16424825)1 Nukui T....Romkes M. (2006)
    822. Effects of genetic polymorphisms CYP1A1, GSTM1, GSTT1 and GSTP1 on urinary 1-hydroxypyrene levels in sugarcane workers. (PubMed id 16914185)1 do Vale Bosso R.M....Conforti-Froes N.D. (2006)
    823. Glutathione S-transferase polymorphisms associated with risk of breast cancer in southern Taiwan. (PubMed id 16713266)4 Chang T.W....Huang W. (2006)
    824. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    825. [Study on serum organochlorines pesticides (DDTs) level, CYP1A1 genetic polymorphism and risk of breast cancer: a case control study] (PubMed id 16792888)1 Li J.Y....Tao P. (2006)
    826. Xenobiotic-metabolizing genes and small-for-gestational-age births: interaction with maternal smoking. (PubMed id 16357593)1 Infante-Rivard C....Guiguet M. (2006)
    827. Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype. (PubMed id 16609368)1 Jiang Z....Nebert D.W. (2006)
    828. Japanese single nucleotide polymorphism database for 267 possible drug-related genes. (PubMed id 16367916)1 Iida A....Nakamura Y. (2006)
    829. EPHX1 polymorphisms and the risk of lung cancer: a HuGE review. (PubMed id 16357600)1 Kiyohara C....Nakanishi Y. (2006)
    830. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)
    831. Metabolism of 4-n-nonylphenol by non-modified and CYP1A1- and CYP1A2-transgenic cell cultures of tobacco. (PubMed id 16402549)1 Berger A....Schmidt B. (2005)
    832. Pharmacokinetics of 5-fluorouracil in rats with diabet es mellitus induced by streptozotocin. (PubMed id 15674819)7 Choi Y.H....Lee M.G. (2005)
    833. Approval summary for erlotinib for treatment of patie nts with locally advanced or metastatic non-small cell lung cancer after failur e of at least one prior chemotherapy regimen. (PubMed id 16166415)7 Johnson J.R....Pazdur R. (2005)
    834. Cytochrome P450 gene polymorphisms and risk of low birth weight. (PubMed id 15712341)1 Chen D....Wang L. (2005)
    835. Metabolism of melatonin by human cytochromes p450. (PubMed id 15616152)7 Ma X....Gonzalez F.J. (2005)
    836. Human CYP1A1 variants lead to differential eicosapentaenoic acid metabolite patterns. (PubMed id 16153604)1 Schwarz D....Roots I. (2005)
    837. CYP1A1 is a major enzyme responsible for the metaboli sm of granisetron in human liver microsomes. (PubMed id 16248838)7 Nakamura H....Kitada M. (2005)
    838. CYP1A1 genetic polymorphisms in Ecuador, South America. (PubMed id 15920291)1 Paz-y-Mino C....Leone P.E. (2005)
    839. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes. (PubMed id 15319333)1 Ramirez J....Ratain M.J. (2004)
    840. Phenacetin and chlorzoxazone biotransformation in agi ng male Fischer 344 rats. (PubMed id 15231049)7 Warrington J.S....von Moltke L.L. (2004)
    841. Genetic polymorphisms of CYP1A1 in a Korean population. (PubMed id 15127181)1 Park D.W....Ryu D.Y. (2004)
    842. [Gene polymorphism of xenobiotics in workers of petroleum and chemical industry] (PubMed id 15152552)1 Makarova O.V....Viktorova T.V. (2004)
    843. The human CYP1A1 gene is regulated in a developmental and tissue-specific fashion in transgenic mice. (PubMed id 15037607)1 Galijatovic A....Tukey R.H. (2004)
    844. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes. (PubMed id 15039299)1 Lalovic B....Shen D.D. (2004)
    845. Analysis of CYP1A1 exon 7 polymorphisms by PCR-SSCP in a Brazilian population and description of two novel gene variations. (PubMed id 15013696)1 Amorim L.M....Pinto L.F. (2004)
    846. Polymorphisms of cytochrome P450 1A1, glutathione S-transferases M1 and T1 in a Turkish population. (PubMed id 15177667)1 Ada A.O....Iscan M. (2004)
    847. Identification of human cytochrome P(450)s that metab olise anti-parasitic drugs and predictions of in vivo drug hepatic clearance fr om in vitro data. (PubMed id 12920490)7 Li X.Q....Masimirembwa C.M. (2003)
    848. Association study of the vitamin D: 1alpha-hydroxylase (CYP1alpha) gene and type 2 diabetes mellitus in a Polish population. (PubMed id 12746631)1 Malecki M.T....Sieradzki J. (2003)
    849. Genetic influence on cigarette-induced cardiovascular disease. (PubMed id 12704594)4 Wang X.L....Wang J. (2003)
    850. Metabolic pathways of dioxin by CYP1A1: species difference between rat and human CYP1A subfamily in the metabolism of dioxins. (PubMed id 12464257)1 Shinkyo R....Inouye K. (2003)
    851. Agonist and chemopreventative ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor. (PubMed id 14560034)1 Hestermann E.V. and Brown M. (2003)
    852. Cytochrome p450 and glutathione transferase expression in human breast cancer. (PubMed id 12738724)1 El-Rayes B.F....Philip P.A. (2003)
    853. Effect of genotype on steady-state CYP1A1 gene expression in human peripheral lymphocytes. (PubMed id 12527337)1 Garte S....Taioli E. (2003)
    854. Cooking methods, metabolic polymorphisms and colorectal cancer. (PubMed id 11917213)4 Pisani P. and Mitton N. (2002)
    855. Genetic susceptibility--molecular epidemiology of head and neck cancer. (PubMed id 11981277)4 Sturgis E.M. and Wei Q. (2002)
    856. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    857. High frequency of CYP1A1*2C allele in Brazilian populations. (PubMed id 12030651)1 Gaspar P.A....Weimer T.A. (2002)
    858. Oxidation of the flavonoids galangin and kaempferide by human liver microsomes and CYP1A1, CYP1A2, and CYP2C9. (PubMed id 11792676)1 Otake Y. and Walle T. (2002)
    859. [The distributive features of three kinds of metabolic genes polymorphisms in population of Han nationality in south area of China] (PubMed id 12170467)1 Shen J....Xu X. (2002)
    860. Low-penetrance genes and their involvement in colorectal cancer susceptibility. (PubMed id 12433710)4 de Jong M.M....Kleibeuker J.H. (2002)
    861. Genetic polymorphisms and lung cancer susceptibility: a review. (PubMed id 12234692)4 Kiyohara C....Hopkin J.M. (2002)
    862. Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption. (PubMed id 12351530)1 Collier A.C....Keelan J.A. (2002)
    863. Metabolism of tamoxifen by recombinant human cytochro me P450 enzymes: formation of the 4-hydroxy, 4'-hydroxy and N-desmethyl metabol ites and isomerization of trans-4-hydroxytamoxifen. (PubMed id 12124303)7 Crewe H.K....Gillam E.M. (2002)
    864. Aromatic DNA adduct levels in coke oven workers: correlation with polymorphisms in genes GSTP1, GSTM1, GSTT1 and CYP1A1. (PubMed id 12034316)1 Teixeira J.P....Rueff J. (2002)
    865. Genetic polymorphisms of glutathione S-transferases M1 and T1 associated with susceptibility to aflatoxin-related hepatocarcinogenesis among chronic hepatitis B carriers: a nested case-control study in Taiwan. (PubMed id 11470760)1 Sun C.A....Santella R.M. (2001)
    866. Childhood acute lymphoblastic leukemia: genetic determinants of susceptibility and disease outcome. (PubMed id 12041882)4 Krajinovic M....Sinnett D. (2001)
    867. Modulation of DNA and protein adducts in smokers by genetic polymorphisms in GSTM1,GSTT1, NAT1 and NAT2. (PubMed id 11470992)1 Godschalk R.W....Van Schooten F.J. (2001)
    868. CYP1A2 is expressed along with CYP1A1 in the human lung. (PubMed id 11485833)1 Wei C....Iba M.M. (2001)
    869. Ethnic differences in distributions of GSTM1 and GSTT1 homozygous 'null' genotypes in India. (PubMed id 11459424)1 Roy B....Sil S.K. (2001)
    870. Biological monitoring the exposure to polycyclic aromatic hydrocarbons of coke oven workers in relation to smoking and genetic polymorphisms for GSTM1 and GSTT1. (PubMed id 11418090)1 van Delft J.H....Hopmans P.M. (2001)
    871. Gene-environment interactions in pancreatic cancer. (PubMed id 12120227)4 Malats N. (2001)
    872. The m2 and m4 polymorphisms in CYP1A1 by NcoI digest-revision of detection method. (PubMed id 10612842)1 Israeli D....Friedman E. (2000)
    873. Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: prediction of in vivo drug-drug interactions. (PubMed id 10805063)7 Katoh M....Yokoi T. (2000)
    874. Cytochrome P4501A1 polymorphisms in South American Indians. (PubMed id 11236859)1 Kvitko K....Hutz M.H. (2000)
    875. Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites. (PubMed id 11093772)7 Marill J....Chabot G.G. (2000)
    876. CYP1A1. (PubMed id 10493257)1 Kawajiri K. (1999)
    877. Polyspecific organic anion transporting polypeptides mediate hepatic uptake of amphipathic type II organic cations. (PubMed id 10490898)7 van Montfoort J.E....Meier P.J. (1999)
    878. Inhibition of rat lung mixed-function oxidase activity following repeated low-level toluene inhalation: possible role of toluene metab olites. (PubMed id 9726784)7 Furman G.M....Schatz R.A. (1998)
    879. Molecular genetics of the human cytochrome P450 monooxygenase superfamily. (PubMed id 9890157)1 Smith G....Wolf C.R. (1998)
    880. In vitro kinetics of two human CYP1A1 variant enzymes suggested to be associated with interindividual differences in cancer susceptibility. (PubMed id 9070254)4 Persson I....Ingelman-Sundberg M. (1997)
    881. Pharmacokinetic-pharmacodynamic relationship of the s elective serotonin reuptake inhibitors. (PubMed id 8968657)7 Baumann P. (1996)
    882. Human cytochrome P450 mono-oxygenase system is suppre ssed by propofol. (PubMed id 7772432)7 Chen T.L....Liu C.C. (1995)
    883. A specific African-American CYP1A1 polymorphism is associated with adenocarcinoma of the lung. (PubMed id 7834609)4 Taioli E....Garte S.J. (1995)
    884. Picrotoxin is a CYP1A1 inducer in rainbow trout hepato cytes. (PubMed id 7575510)7 Sadar M.D....Andersson T.B. (1995)
    885. A race-specific genetic polymorphism in the CYP1A1 gene is not associated with lung cancer in African Americans. (PubMed id 8020143)4 Kelsey K.T....Spitz M.R. (1994)
    886. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
    887. Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae. (PubMed id 8095225)1 Eugster H.P....Sengstag C. (1993)
    888. CYP1A1: friend or foe? (PubMed id 8313840)1 Beresford A.P. (1993)
    889. Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain. (PubMed id 8442765)1 Ghersi-Egea J.F....Minn A. (1993)
    890. Xenobiotic responsive element in the 5'-upstream region of the human P-450c gene. (PubMed id 1761516)1 Kubota M....Fujii-Kuriyama Y. (1991)
    891. Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P450IA1 gene. (PubMed id 1691986)1 Kawajiri K....Watanabe J. (1990)
    892. Two RFLPs associated with the human P1450 gene linked to the MPI locus on chromosome 15 [HGM8 D15S8] (PubMed id 3714481)1 Jaiswal A.K. and Nebert D.W. (1986)
    893. Assignment of the human 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 gene to chromosome 15. (PubMed id 4000952)1 Hildebrand C.E....Nebert D.W. (1985)
    894. Characterization of the interaction of amphipathic cytochrome b5 with stearyl coenzyme A desaturase and NADPH:cytochrome P-450 reductase. (PubMed id 6102994)1 Dailey H.A. and Strittmatter P. (1980)
    895. Environmental factors and aryl hydrocarbon hydroxylase activity (CYP1A1 phenotype) in human lymphocytes. (PubMed id 9465551)9 Kiyohara C. and Hirohata T. (1997)
    896. Detection of CYP1A1 protein in human liver and induction by TCDD in precision-cut liver slices incubated in dynamic organ culture. (PubMed id 9744530)9 Drahushuk A.T....Olson J.R. (1998)
    897. Monocyte aryl hydrocarbon hydroxylase (AHH) activity mimics Kupffer cell and hepatocyte AHH activity in an animal model of liver disease. (PubMed id 1802352)9 Peterson T.C....Malatjalian D.A. (1991)
    898. An autoregulatory loop controlling CYP1A1 gene expression: role of H(2)O(2) and NFI. (PubMed id 10490621)9 Morel Y....Barouki R. (1999)
    899. Expression of human cytochrome P450 1A1 in DNA repair deficient and proficient human fibroblasts stably transformed with an inducible expression vector. (PubMed id 8353849)9 States J.C....Runge-Morris M. (1993)
    900. The role of redox-sensitive transcription factors NF-kappaB and AP-1 in the modulation of the Cyp1a1 gene by mercury, lead, and copper. (PubMed id 18078826)9 Korashy H.M. and El-Kadi A.O. (2008)
    901. Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas. (PubMed id 17200336)9 Chang J.T....Lin P. (2007)
    902. Systemic effects of arctic pollutants in beluga whales indicated by CYP1A1 expression. (PubMed id 16263517)9 Wilson J.Y....Stegeman J.J. (2005)
    903. tert-Butylhydroquinone is a novel aryl hydrocarbon receptor ligand. (PubMed id 15608132)9 Gharavi N. and El-Kadi A.O. (2005)
    904. Arsenite inhibition of CYP1A1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is independent of cell cycle arrest. (PubMed id 15630080)9 Bonzo J.A....Tukey R.H. (2005)
    905. Mechanisms of arsenite-mediated decreases in benzo[k] fluoranthene-induced human cytochrome P4501A1 levels in HepG2 cells. (PubMed id 15576448)9 Bessette E.E....Kaminsky L.S. (2005)
    906. Regulation of NAD(P)H:quinone oxidoreductase 1 gene expression by CYP1A1 activity. (PubMed id 15044633)9 Marchand A....Garlatti M. (2004)
    907. Novel functional association of serine palmitoyltransferase subunit 1-A peptide in sphingolipid metabolism with cytochrome P4501A1 transactivation and proliferative capacity of the human Glioma LN18 brain tumor cell line. (PubMed id 16968971)9 Yerokun T. and Stewart J. (2006)
    908. Suppressive effect of 1-nitropyrene on benzo[a]pyrene-induced CYP1A1 protein expression in HepG2 cells. (PubMed id 16280210)9 Cherng S.H....Lee H. (2006)
    909. Expression of aryl hydrocarbon receptor repressor in normal human tissues and inducibility by polycyclic aromatic hydrocarbons in human tumor-derived cell lines. (PubMed id 12655030)9 Tsuchiya Y....Yokoi T. (2003)
    910. Regulatory interactions among three members of the vertebrate aryl hydrocarbon receptor family: AHR repressor, AHR1, and AHR2. (PubMed id 11742002)9 Karchner S.I....Hahn M.E. (2002)
    911. Detailed characterization of experimentally derived human hepatic CYP1A1 activity and expression using differential inhibition of ethoxyresorufin O-deethylation by fluvoxamine. (PubMed id 11599655)9 Sy S.K....Kalow W. (2001)
    912. Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially. (PubMed id 10359656)9 Ciolino H.P....Yeh G.C. (1999)
    913. The relationship between CYP1A1 aryl hydrocarbon hydroxylase activity and lung cancer in a Japanese population. (PubMed id 9731718)9 Kiyohara C....Hirohata T. (1998)
    914. Cytochrome P450 1A1 induction in rat lymphoid tissues following in vivo and in vitro exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin requires protein kinase C. (PubMed id 9392454)9 Stephen F.D....Olson J.R. (1997)
    915. The relationship between aryl hydrocarbon hydroxylase and polymorphisms of the CYP1A1 gene. (PubMed id 8609043)9 Kiyohara C....Inutsuka S. (1996)
    916. Cytochrome P4501A1 mediates the metabolism of 2,3,7,8-tetrachlorodibenzofuran in the rat and human. (PubMed id 8236259)9 Tai H.L....Olson J.R. (1993)
    917. Construction of a system that simultaneously evaluate s CYP1A1 and CYP1A2 induction in a stable human-derived cell line using a dual reporter plasmid. (PubMed id 20460824)9 Sato W....Nagata K. (2010)
    918. Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1. (PubMed id 19330882)9 Kabler S.L....Townsend A.J. (2009)
    919. 1-Nitropyrene stabilizes the mRNA of cytochrome P450 1a1, a carcinogen-metabolizing enzyme, via the Akt pathway. (PubMed id 19961161)9 Chu W.C....Su J.G. (2009)
    920. Transcriptional activation and posttranscriptional modification of Cyp1a1 by arsenite, cadmium, and chromium. (PubMed id 17606337)9 Elbekai R.H. and El-Kadi A.O. (2007)
    921. Induction of CYP1A1 in tumor cells by the antitumor agent 2-[4-amino-3-methylphenyl]-5-fluoro-benzothiazole: a potential surrogate marker for patient sensitivity. (PubMed id 14707267)9 Hose C.D....Monks A. (2003)
    922. Oltipraz inhibits 3-methylcholanthrene induction of CYP1A1 by CCAAT/enhancer-binding protein activation. (PubMed id 12941938)9 Cho I.J. and Kim S.G. (2003)
    923. Correlation between gene expression of aryl hydrocarbon receptor (AhR), hydrocarbon receptor nuclear translocator (Arnt), cytochromes P4501A1 (CYP1A1) and 1B1 (CYP1B1), and inducibility of CYP1A1 and CYP1B1 in human lymphocytes. (PubMed id 12520072)9 Lin P....Chang T.H. (2003)
    924. Human lung microsomal cytochrome P4501A1 (CYP1A1) activities: impact of smoking status and CYP1A1, aryl hydrocarbon receptor, and glutathione S-transferase M1 genetic polymorphisms. (PubMed id 11489750)9 Smith G.B....Massey T.E. (2001)
    925. Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated CYP1A1 and CYP1B1 induction by 12-O-tetradecanoylphorbol-13-acetate: role of transforming growth factor beta and mitogen-activated protein kinases. (PubMed id 11728381)9 Guo M....Reiners J.J. (2001)
    926. An uncommon phenotype of poor inducibility of CYP1A1 in human lung is not ascribable to polymorphisms in the AHR, ARNT, or CYP1A1 genes. (PubMed id 11186136)9 Anttila S....Hankinson O. (2000)
    927. Characterization of the dose-response of CYP1B1, CYP1A1, and CYP1A2 in the liver of female Sprague-Dawley rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. (PubMed id 9931287)9 Walker N.J....Sutter T.R. (1999)
    928. Characterization of the rabbit CYP1A1 and CYP1A2 genes: developmental and dioxin-inducible expression of rabbit liver P4501A1 and P4501A2. (PubMed id 1567227)9 Strom D.K....Tukey R.H. (1992)
    929. Characterization of major phytocannabinoids, cannabid iol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 en zymes. (PubMed id 20117100)9 Yamaori S....Watanabe K. (2010)
    930. Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: an in vitro and in vivo study. (PubMed id 19033395)9 Wu J.P....Lin P. (2009)
    931. Conserved genomic structure of the Cyp1a1 and Cyp1a2 loci and their dioxin responsive elements cluster. (PubMed id 19026991)9 Nukaya M. and Bradfield C.A. (2009)
    932. Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements. (PubMed id 18502397)9 Yoshinari K....Yamazoe Y. (2008)
    933. Interindividual variation in CYP1A1 expression in breast tissue and the role of genetic polymorphism. (PubMed id 11062177)9 Goth-Goldstein R....Russell M. (2000)
    934. Characterization of CYP1B1 and CYP1A1 expression in human mammary epithelial cells: role of the aryl hydrocarbon receptor in polycyclic aromatic hydrocarbon metabolism. (PubMed id 9622076)9 Larsen M.C....Jefcoate C.R. (1998)
    935. Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells. (PubMed id 9498279)9 Spink D.C....Sutter T.R. (1998)
    936. Cell-specific regulation of human CYP1A1 and CYP1B1 genes. (PubMed id 9102211)9 Kress S. and Greenlee W.F. (1997)
    937. Genetic polymorphism of cytochromes P450 1A1, 2D6 and 2E1: regulation and toxicological significance. (PubMed id 7620940)9 Rannug A....Ingelman-Sundberg M. (1995)
    938. [A role of aryl hydrocarbon hydroxylase inducibility in susceptibility to lung carcinogenesis] (PubMed id 8126925)9 Kiyohara C. and Hirohata T. (1994)
    939. Cytotoxicity and genotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol in CYP1A1-expressing human fibroblasts quantitatively correlate with CYP1A1 expression level. (PubMed id 7923575)9 Quan T....States J.C. (1994)
    940. CYP1A1 specificity of Verlukast epoxidation in mice, rats, rhesus monkeys, and humans. (PubMed id 7905381)9 Grossman S.J....Yergey J.A. (1993)
    941. Racial differences in restriction fragment length polymorphisms and messenger RNA inducibility of the human CYP1A1 gene. (PubMed id 8093594)9 Cosma G....Garte S.J. (1993)
    942. Potentiation of CYP1A1 gene expression in MCF-7 human breast cancer cells cotreated with 2,3,7,8-tetrachlorodibenzo-p-dioxin and 12-O-tetradecanoylphorbol-13-acetate. (PubMed id 8396892)9 Moore M....Safe S. (1993)
    943. Is aryl hydrocarbon hydroxylase activity a new prognostic indicator for breast cancer? (PubMed id 2021546)9 Pyykko K....Perkio T. (1991)
    944. Persistent induction of cytochrome P4501A1 in human h epatoma cells by 3-methylcholanthrene: evidence for sustained transcriptional a ctivation of the CYP1A1 promoter. (PubMed id 20051482)9 Fazili I.S....Moorthy B. (2010)
    945. CYP1A1 and CYP1B1 gene expression and DNA adduct form ation in normal human mammary epithelial cells exposed to benzo[a]pyrene in the absence or presence of chlorophyllin. (PubMed id 20163913)9 John K....Weston A. (2010)
    946. Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells. (PubMed id 18842620)9 Taylor R.T....Hankinson O. (2009)
    947. Constitutive regulation of CYP1B1 by the aryl hydrocarbon receptor (AhR) in pre-malignant and malignant mammary tissue. (PubMed id 18059014)9 Yang X....Sherr D.H. (2008)
    948. HDAC1 bound to the Cyp1a1 promoter blocks histone acetylation associated with Ah receptor-mediated trans-activation. (PubMed id 17707923)9 Schnekenburger M....Puga A. (2007)
    949. Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers. (PubMed id 15766589)9 Stiborova M....Hodek P. (2005)
    950. PPARalpha activation potentiates AhR-induced CYP1A1 expression. (PubMed id 16137816)9 Fallone F....Lacarelle B. (2005)
    951. Regulatory mechanisms modulating the expression of cytochrome P450 1A1 gene by heavy metals. (PubMed id 16093525)9 Korashy H.M. and El-Kadi A.O. (2005)
    952. CYP1A1 and CYP1B1 expressions in medulloblastoma cells are AhR-independent and have no direct link with resveratrol-induced differentiation and apoptosis. (PubMed id 15893423)9 Wu M.L....Liu J. (2005)
    953. Induction of CYP1A1 and CYP1B1 and formation of carcinogen-DNA adducts in normal human mammary epithelial cells treated with benzo[a]pyrene. (PubMed id 15808407)9 Keshava C....Weston A. (2005)
    954. CCAAT/enhancer binding protein activation by PD98059 contributes to the inhibition of AhR-mediated 3-methylcholanthrene induction of CYP1A1. (PubMed id 16393856)9 Shin S.M....Kim S.G. (2005)
    955. Constitutive and inducible expression of cytochromes P4501A (CYP1A1 and CYP1A2) in normal prostate and prostate cancer cells. (PubMed id 14743400)9 Sterling K.M. and Cutroneo K.R. (2004)
    956. Comparison of gene expression patterns between 2,3,7,8-tetrachlorodibenzo-p-dioxin and a natural arylhydrocarbon receptor ligand, indirubin. (PubMed id 15056799)9 Adachi J....Matsuda T. (2004)
    957. Functional evaluation of novel single nucleotide polymorphisms and haplotypes in the promoter regions of CYP1B1 and CYP1A1 genes. (PubMed id 12884367)9 Han W....Spivack S.D. (2003)
    958. Benzo[g,h,i]perylene synergistically transactivates benzo[a]pyrene-induced CYP1A1 gene expression by aryl hydrocarbon receptor pathway. (PubMed id 11141357)9 Cherng S.H....Lee H. (2001)
    959. Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated aryl hydrocarbon receptor transformation and CYP1A1 induction by the phosphatidylinositol 3-kinase inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002). (PubMed id 10927021)9 Guo M....Reiners J.J. (2000)
    960. Induction of cytochrome P450 1A1 in human hepatoma HepG2 cells by 6-nitrochrysene. (PubMed id 11033235)9 Chen R.M....Ueng T.H. (2000)
    961. Expression of CYP1A1 and CYP1B1 depends on cell-specific factors in human breast cancer cell lines: role of estrogen receptor status. (PubMed id 10357772)9 Angus W.G....Jefcoate C.R. (1999)
    962. The steroid hormone dehydroepiandrosterone inhibits CYP1A1 expression in vitro by a post-transcriptional mechanism. (PubMed id 10575002)9 Ciolino H.P. and Yeh G.C. (1999)
    963. The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor. (PubMed id 10188874)9 Ciolino H.P. and Yeh G.C. (1999)
    964. Induction and localization of cytochrome P450 1B1 (CYP1B1) protein in the livers of TCDD-treated rats: detection using polyclonal antibodies raised to histidine-tagged fusion proteins produced and purified from bacteria. (PubMed id 9525272)9 Walker N.J....Sutter T.R. (1998)
    965. Localization of CYP1A1 mRNA in human lung by in situ hybridization: comparison with immunohistochemical findings. (PubMed id 9639391)9 Saarikoski S.T....Anttila S. (1998)
    966. Diosmin and diosmetin are agonists of the aryl hydrocarbon receptor that differentially affect cytochrome P450 1A1 activity. (PubMed id 9661887)9 Ciolino H.P....Yeh G.C. (1998)
    967. Cytochrome P4501A1 and glutathione S-transferase M1 genotypes as risk factors for prostate cancer in Japan. (PubMed id 9861231)9 Murata M....Yatani R. (1998)
    968. Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor. (PubMed id 9865727)9 Ciolino H.P....Yeh G.C. (1998)
    969. Truncal tumor site is associated with high risk of multiple basal cell carcinoma and is influenced by glutathione S-transferase, GSTT1, and cytochrome P450, CYP1A1 genotypes, and their interaction. (PubMed id 9077484)9 Lear J.T....Fryer A.A. (1997)
    970. Genotyping of the CYP1A1 and GSTM1 genes in esophageal carcinoma patients with special reference to smoking. (PubMed id 9307183)9 Nimura Y....Iida F. (1997)
    971. Effects of polychlorinated dibenzo-p-dioxin and dibenzofuran congeners in human lymphoblastoid cells on aryl hydrocarbon hydroxylase activity. (PubMed id 8528652)9 Kiyohara C....Masuda Y. (1995)
    972. Detection of CYP1A1 gene polymorphism using designed RFLP and distributions of CYP1A1 genotypes in Japanese. (PubMed id 7591186)9 Oyama T....Yasumoto K. (1995)
    973. Combined effect of CYP1A1 inducibility and GSTM1 polymorphism on histological type of lung cancer. (PubMed id 8020145)9 Anttila S....Vainio H. (1994)
    974. Enzyme induction of the early chick embryo by airborne particulate extracts. (PubMed id 8481108)9 Matsumoto H. (1993)
    975. Interleukin-1 beta suppresses the induction of P4501A1 and P4501A2 mRNAs in isolated hepatocytes. (PubMed id 1569064)9 Barker C.W....Pasco D.S. (1992)
    976. Stable expression of mouse Cyp1a1 and human CYP1A2 cDNAs transfected into mouse hepatoma cells lacking detectable P450 enzyme activity. (PubMed id 2206399)9 Puga A....Nebert D.W. (1990)
    977. 1,10-phenanthroline stabilizes mRNA of the carcinogen -metabolizing enzyme, cytochrome P450 1a1. (PubMed id 19896525)9 Chou M.T....Su J.G. (2010)
    978. Importance of CYP1A1 and CYP1B1 in bioactivation of b enzo[a]pyrene in human lung cell lines. (PubMed id 19879933)9 Uppstad H....Mollerup S. (2010)
    979. Omeprazole alleviates benzo[a]pyrene cytotoxicity by inhibition of CYP1A1 activity in human and mouse hepatoma cells. (PubMed id 18793272)9 Shiizaki K....Yagi T. (2008)
    980. Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). (PubMed id 17052995)9 Ma X....Gonzalez F.J. (2007)
    981. Regulation of CYP1A1 gene expression by the antioxidant tert-butylhydroquinone. (PubMed id 16581943)9 Schreiber T.D....Munzel P.A. (2006)
    982. Cytochrome P450 1A1 and 1B1 in human blood lymphocytes are not suitable as biomarkers of exposure to dioxin-like compounds: polymorphisms and interindividual variation in expression and inducibility. (PubMed id 15659568)9 van Duursen M.B....van den Berg M. (2005)
    983. The role of protein kinase C in regulation of TCDD-mediated CYP1A1 gene expression. (PubMed id 15947024)9 Machemer D.E. and Tukey R.H. (2005)
    984. Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid. (PubMed id 15041462)9 Schwarz D....Roots I. (2004)
    985. Induction of CYP1A1 and CYP1B1 in T-47D human breast cancer cells by benzo[a]pyrene is diminished by arsenite. (PubMed id 11854143)9 Spink D.C....Kaminsky L.S. (2002)
    986. CYP1A1 induction by pyridine and its metabolites in HepG2 cells. (PubMed id 12147272)9 Iba M.M....Fung J. (2002)
    987. Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes. (PubMed id 12384524)9 Stiborova M....Frei E. (2002)
    988. A high-throughput cell-based reporter gene system for measurement of CYP1A1 induction. (PubMed id 12628305)9 Cui X....Cheng K.C. (2002)
    989. Induction of CYP1A by benzo[k]fluoranthene in human hepatocytes: CYP1A1 or CYP1A2? (PubMed id 11370663)9 Liu N....Kaminsky L.S. (2001)
    990. Differential metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 variants. (PubMed id 11238186)9 Schwarz D....Roots I. (2001)
    991. Failure of Ah receptor to mediate induction of cytochromes P450 in the CYP1 family in the human hepatoma line SK-Hep-1. (PubMed id 11147830)9 Roberts E.A....Yang S. (2000)
    992. Estrogen receptor reduces CYP1A1 induction in cultured human endometrial cells. (PubMed id 9920887)9 Ricci M.S....Toscano W.A. (1999)
    993. Prognostic significance of germ line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer. (PubMed id 8706015)9 Goto I....Kawajiri K. (1996)
    994. Interferon-mediated changes in the expression of CYP1A1 in human B lymphoblastoid (AHH-1 TK +/-) cells. (PubMed id 8834482)9 Delaporte E....Renton K.W. (1995)
    995. Characterization of hamster CYP1A1 gene: inducible expression and negative regulation. (PubMed id 7883754)9 Sagami I....Watanabe M. (1994)
    996. 1462V mutation in the human CYP1A1 gene: lack of corr elation with either the Msp I 1.9 kb (M2) allele or CYP1A1 inducibility in a th ree-generation family of east Mediterranean descent. (PubMed id 7516235)9 Wedlund P.J....Nebert D.W. (1994)
    997. CYP1A1 mRNA levels as a human exposure biomarker: use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes. (PubMed id 8222045)9 Vanden Heuvel J.P....Bell D.A. (1993)
    998. 2,3,7,8-tetrachlorodibenzo-p-dioxin increases reactiv e oxygen species production in human endothelial cells via induction of cytochr ome P4501A1. (PubMed id 20171976)9 Kopf P.G. and Walker M.K. (2010)
    999. Arsenite down-regulates cytochrome P450 1A1 at the tr anscriptional and posttranslational levels in human HepG2 cells. (PubMed id 20188822)9 Anwar-Mohamed A. and El-Kadi A.O. (2010)
    1000. Chlorophyllin significantly reduces benzo[a]pyrene-DNA adduct formation and alters cytochrome P450 1A1 and 1B1 expression and EROD activity in normal human mammary epithelial cells. (PubMed id 19152381)9 Keshava C....Weston A. (2009)
    1001. The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity. (PubMed id 18329153)9 StiborovA! M....Arlt V.M. (2008)
    1002. Analysis of CYP1A1 induction in single cells of urothelial cell populations by flow cytometry. (PubMed id 18797853)9 Plottner S....Follmann W. (2008)
    1003. Modulation of TCDD-mediated induction of cytochrome P450 1A1 by mercury, lead, and copper in human HepG2 cell line. (PubMed id 17889500)9 Korashy H.M. and El-Kadi A.O. (2008)
    1004. A real-time fluorescence assay for measuring N-dealkylation. (PubMed id 17035601)9 Mayer R.T....Mayer G.E. (2007)
    1005. Arecoline inhibits the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cytochrome P450 1A1 activation in human hepatoma cells. (PubMed id 17234337)9 Chang E.E....Tsou T.C. (2007)
    1006. Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation. (PubMed id 17433523)9 Chung J.Y....Kim J.M. (2007)
    1007. Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line. (PubMed id 17560947)9 Dragin N....Nebert D.W. (2007)
    1008. Investigation of sanguinarine and chelerythrine effec ts on CYP1A1 expression and activity in human hepatoma cells. (PubMed id 16115718)9 ZdarilovA! A....DvorA!k Z. (2006)
    1009. Increased cytochrome P4501B1 gene expression in peripheral leukocytes of municipal waste incinerator workers. (PubMed id 16098693)9 Hu S.W....Lin P. (2006)
    1010. Kimchi and soybean pastes are risk factors of gastric cancer. (PubMed id 15929164)9 Nan H.M....Kim H. (2005)
    1011. Association of CYP1A1 polymorphisms with differential metabolic activation of 17beta-estradiol and estrone. (PubMed id 15805301)9 Kisselev P....Schwarz D. (2005)
    1012. Significant association between nonsyndromic oral clefts and arylhydrocarbon receptor nuclear translocator (ARNT). (PubMed id 15368494)9 Kayano S....Matsubara Y. (2004)
    1013. Superinduction of CYP1A1 in MCF10A cultures by cycloheximide, anisomycin, and puromycin: a process independent of effects on protein translation and unrelated to suppression of aryl hydrocarbon receptor proteolysis by the proteasome. (PubMed id 15385644)9 Joiakim A....Reiners J.J. (2004)
    1014. AH receptor antagonist inhibits constitutive CYP1A1 and CYP1B1 expression in rat BP8 cells. (PubMed id 15047159)9 Roblin S....Harper P.A. (2004)
    1015. Methoxyestrogens exert feedback inhibition on cytochrome P450 1A1 and 1B1. (PubMed id 12810639)9 Dawling S....Parl F.F. (2003)
    1016. Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells. (PubMed id 12927368)9 Nakajima M....Yokoi T. (2003)
    1017. Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium. (PubMed id 11452143)9 Bofinger D.P....Olson J.R. (2001)
    1018. Increased expression of cytochrome p450 1A1 and 1B1 genes in anti-estrogen-resistant human breast cancer cell lines. (PubMed id 11093812)9 Brockdorff B.L....Lykkesfeldt A.E. (2000)
    1019. N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE) a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs. (PubMed id 10755318)9 Brandes L.J....LaBella F.S. (2000)
    1020. Genetic polymorphism of drug-metabolizing enzymes and susceptibility to oral cancer. (PubMed id 10506106)9 Sato M....Amagasa T. (1999)
    1021. Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers: studies in upper aerodigestive tract cancers. (PubMed id 10022746)9 Matthias C....Strange R.C. (1998)
    1022. Comparative inhibition of human cytochromes P450 1A1 and 1A2 by flavonoids. (PubMed id 9763404)9 Zhai S....Vestal R.E. (1998)
    1023. Cell-specific differences in the susceptibility of potential cellular targets of human origin derived from blood and lung following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). (PubMed id 9538942)9 Lang D.S....Koren H.S. (1998)
    1024. Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells. (PubMed id 9054634)9 Hakkola J....Raunio H. (1997)
    1025. Polymorphisms of CYP1A1 and GSTM1 influence the in vivo function of CYP1A2. (PubMed id 9202749)9 MacLeod S....Lang N.P. (1997)
    1026. Downregulation of aryl hydrocarbon receptor function and cytochrome P450 1A1 induction by expression of Ha-ras oncogenes. (PubMed id 9210956)9 Reiners J.J....Elferink C. (1997)
    1027. Human Ah receptor (AHR) gene: localization to 7p15 and suggestive correlation of polymorphism with CYP1A1 inducibility. (PubMed id 9170146)9 Micka J....Nebert D.W. (1997)
    1028. Germ line polymorphisms in cytochrome-P450 1A1 (C4887 CYP1A1) and methylenetetrahydrofolate reductase (MTHFR) genes and endometrial cancer susceptibility. (PubMed id 9450474)9 Esteller M....Reventos J. (1997)
    1029. Development of a human lymphoblastoid cell line constitutively expressing human CYP1B1 cDNA: substrate specificity with model substrates and promutagens. (PubMed id 9106248)9 Crespi C.L....Sutter T.R. (1997)
    1030. Frequency of mutant CYP1A1, NAT2 and GSTM1 alleles in normal Indians and Malays. (PubMed id 8563767)9 Zhao B....Gong N.H. (1995)
    1031. An inhibitory monoclonal anti-protein antibody and an anti-peptide antibody share an epitope on rat cytochrome P-450 enzymes CYP1A1 and CYP1A2. (PubMed id 7678502)9 Edwards R.J....Boobis A.R. (1993)
    1032. Stimulatory effect of the CYP1A1 inducer 2,3,7,8-tetrachlorodibenzo-p-dioxin on the reproduction of HIV-1 in human lymphoid cell culture. (PubMed id 7687806)9 Tsyrlov I.B. and Pokrovsky A. (1993)
    1033. Mechanism of action of aryl hydrocarbon receptor antagonists: inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression. (PubMed id 1329656)9 Merchant M....Safe S. (1992)
    1034. Localization of CYP1A1 and CYP1A2 messenger RNA in normal human liver and in hepatocellular carcinoma by in situ hybridization. (PubMed id 1657755)9 McKinnon R.A....McManus M.E. (1991)
    1035. Pulmonary drug-metabolizing enzyme in alveolar macrophages in relation to cigarette smoking. (PubMed id 2232364)9 Abe S....Kawakami Y. (1990)
    1036. Analysis of human CYP1A1 and CYP1A2 genes and their s hared bidirectional promoter in eight world populations. (PubMed id 19802894)9 Jorge-Nebert L.F....Nebert D.W. (2010)
    1037. Augmentation of 3-methylcholanthrene-induced bioactiv ation in the human hepatoma cell line HepG2 by the calcium channel blocker nica rdipine. (PubMed id 20067464)9 Hosaka T....Degawa M. (2010)
    1038. Cytochrome P450 1A1 gene regulation by UVB involves c rosstalk between the aryl hydrocarbon receptor and nuclear factor kappaB. (PubMed id 20132803)9 Luecke S....Rannug A. (2010)
    1039. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and beta-naphthof lavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon recepto r-dependant mechanism. (PubMed id 19969063)9 Zordoky B.N. and El-Kadi A.O. (2010)
    1040. Estrogen receptor subtype- and promoter-specific modu lation of aryl hydrocarbon receptor-dependent transcription. (PubMed id 19470599)9 WihlAcn B....Matthews J. (2009)
    1041. HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling. (PubMed id 19158084)9 Kekatpure V.D....Subbaramaiah K. (2009)
    1042. Role of human CYP1A1 and NAT2 in 2-amino-1-methyl-6-p henylimidazo[4,5-b]pyridine-induced mutagenicity and DNA adducts. (PubMed id 19301197)9 Bendaly J....Hein D.W. (2009)
    1043. Ascorbic acid suppresses the 2,3,7,8-tetrachloridibenxo-p-dioxin (TCDD)-induced CYP1A1 expression in human HepG2 cells. (PubMed id 19268519)9 Chang H.J....Jung Y.D. (2009)
    1044. Persistent induction of cytochrome P450 (CYP)1A enzym es by 3-methylcholanthrene in vivo in mice is mediated by sustained transcripti onal activation of the corresponding promoters. (PubMed id 19900403)9 Jiang W....Moorthy B. (2009)
    1045. Resveratrol inhibits dioxin-induced expression of hum an CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding g enes. (PubMed id 19376845)9 Beedanagari S.R....Hankinson O. (2009)
    1046. Potent inhibition of human cytochrome P450 1B1 by tet ramethoxystilbene. (PubMed id 19463925)9 Chun Y.J....Kim M.Y. (2009)
    1047. Expression of AhR, CYP1A1, GSTA1, c-fos and TGF-alpha in skin lesions from dioxin-exposed humans with chloracne. (PubMed id 18329192)9 Tang N.J....Bai Z.P. (2008)
    1048. In vitro biotransformation of imatinib by the tumor expressed CYP1A1 and CYP1B1. (PubMed id 18188833)9 Rochat B....Michielin O. (2008)
    1049. JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes. (PubMed id 17959153)9 Dvorak Z....Ulrichova J. (2008)
    1050. Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells. (PubMed id 17599377)9 Khan S....Safe S. (2007)
    1051. Differential effect of arecoline on the endogenous dioxin-responsive cytochrome P450 1A1 and on a stably transfected dioxin-responsive element-driven reporter in human hepatoma cells. (PubMed id 17707585)9 Chao H.R....Tsou T.C. (2007)
    1052. The anticancer drug ellipticine is a potent inducer o f rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism. (PubMed id 17656468)9 AimovA! D....StiborovA! M. (2007)
    1053. 3-Methylcholanthrene elicits DNA adduct formation in the CYP1A1 promoter region and attenuates reporter gene expression in rat H4IIE cells. (PubMed id 17276403)9 Moorthy B....Jiang W. (2007)
    1054. Growth kinetics in MCF-7 cells modulate benzo[a]pyrene-induced CYP1A1 up-regulation. (PubMed id 17237483)9 Jiao H....Martin F.L. (2007)
    1055. Biotransformation of metamitron by human p450 expressed in transgenic tobacco cell cultures. (PubMed id 16484082)9 Bode M....Schmidt B. (2006)
    1056. The expression of xenobiotic-metabolizing enzymes in human prostate and in prostate epithelial cells (PECs) derived from primary cultures. (PubMed id 16496416)9 Al-Buheissi S.Z....Phillips D.H. (2006)
    1057. For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential. (PubMed id 16636061)9 Dragin N....Nebert D.W. (2006)
    1058. Duplicate aryl hydrocarbon receptor repressor genes (ahrr1 and ahrr2) in the zebrafish Danio rerio: structure, function, evolution, and AHR-dependent regulation in vivo. (PubMed id 16122694)9 Evans B.R....Hahn M.E. (2005)
    1059. 5,7-Dimethoxyflavone downregulates CYP1A1 expression and benzo[a]pyrene-induced DNA binding in Hep G2 cells. (PubMed id 15661813)9 Wen X....Walle T. (2005)
    1060. Effects of zearalenone on mRNA expression and activity of cytochrome P450 1A1 and 1B1 in MCF-7 cells. (PubMed id 15157572)9 Yu Z....Li Y. (2004)
    1061. Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells. (PubMed id 15355884)9 Brantley E....Stinson S.F. (2004)
    1062. Occupational exposure to polycyclic aromatic hydrocarbons suppresses constitutive expression of CYP1B1 on the transcript level in human leukocytes. (PubMed id 15471096)9 Lemm F....Roos P.H. (2004)
    1063. Suppression by p38 MAP kinase inhibitors (pyridinyl imidazole compounds) of Ah receptor target gene activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin and the possible mechanism. (PubMed id 14594946)9 Shibazaki M....Kikuchi H. (2004)
    1064. Modulation of AhR-mediated CYP1A1 mRNA and EROD activities by 17beta-estradiol and dexamethasone in TCDD-induced H411E cells. (PubMed id 14691211)9 Lai K.P....Wong C.K. (2004)
    1065. Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells. (PubMed id 15142886)9 Chen Z.H....Surh Y.J. (2004)
    1066. Increased expression of cytochrome P4501B1 in peripheral leukocytes from lung cancer patients. (PubMed id 15093676)9 Wu M.F....Lin P. (2004)
    1067. Sensitivity of renal cell carcinoma to aminoflavone: role of CYP1A1. (PubMed id 15017268)9 Loaiza-PAcrez A.I....Vistica D.T. (2004)
    1068. Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer. (PubMed id 15028720)9 Nebert D.W....Gonzalez F.J. (2004)
    1069. Real-time polymerase chain reaction analysis of CYP1B1 gene expression in human liver. (PubMed id 12520071)9 Chang T.K....Bandiera S.M. (2003)
    1070. Estrogen regulates Ah responsiveness in MCF-7 breast cancer cells. (PubMed id 12970067)9 Spink D.C....Spink B.C. (2003)
    1071. Quantitative analysis of the Ah receptor/cytochrome P450 CYP1B1/CYP1A1 signalling pathway. (PubMed id 12754102)9 McFadyen M.C....Murray G.I. (2003)
    1072. Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole. (PubMed id 11752201)9 Loaiza-PAcrez A.I....Sausville E.A. (2002)
    1073. Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CYP1A2 gene. (PubMed id 12438513)9 Kondraganti S.R....Moorthy B. (2002)
    1074. The redox protein thioredoxin-1 regulates the constitutive and inducible expression of the estrogen metabolizing cytochromes P450 1B1 and 1A1 in MCF-7 human breast cancer cells. (PubMed id 12376470)9 Husbeck B. and Powis G. (2002)
    1075. Differential inhibition of human CYP1A1 and CYP1A2 by quinidine and quinine. (PubMed id 11765139)9 Ching M.S....Ghabrial H. (2001)
    1076. Low synthesis of retinoic acid due to impaired cytochrome P450 1a1 expression in mouse xeroderma pigmentosum fibroblasts. (PubMed id 11378441)9 Ding J....Ichikawa Y. (2001)
    1077. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells. (PubMed id 11294972)9 Sanderson J.T....van den Berg M. (2001)
    1078. Induction and regulation of the carcinogen-metabolizing enzyme CYP1A1 by marijuana smoke and delta (9)-tetrahydrocannabinol. (PubMed id 11245634)9 Roth M.D....Hankinson O. (2001)
    1079. Regulation of Cyp1a1 induction by dioxin as a function of cell cycle phase. (PubMed id 11602686)9 Santini R.P....Reiners J.J. (2001)
    1080. Polymorphisms of human aryl hydrocarbon receptor (AhR) gene in a French population: relationship with CYP1A1 inducibility and lung cancer. (PubMed id 11698344)9 Cauchi S.... Massaad-Massade L. (2001)
    1081. Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells. (PubMed id 11226373)9 Delescluse C....Rahmani R. (2001)
    1082. Is CYP1A1 induction always related to AHR signaling pathway? (PubMed id 11090948)9 Delescluse C....Rahmani R. (2000)
    1083. Influence of genetic susceptibility on the urinary excretion of 8-hydroxydeoxyguanosine of firefighters. (PubMed id 10810125)9 Hong Y.C....Ha E.H. (2000)
    1084. Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: prediction of in vivo drug interactions. (PubMed id 10718780)9 Ohyama K....Yokoi T. (2000)
    1085. Gender differences in genetic susceptibility for lung cancer. (PubMed id 11137199)9 Dresler C.M....Clapper M.L. (2000)
    1086. Estrogen enhances induction of cytochrome P-4501A1 by 2,3,7, 8-tetrachlorodibenzo-p-dioxin in liver of female Long-Evans rats. (PubMed id 10601559)9 Sarkar S....Sone H. (2000)
    1087. Comparative effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on MCF-7, RL95-2, and LNCaP cells: role of target steroid hormones in cellular responsiveness to CYP1A1 induction. (PubMed id 11281733)9 Jana N.R....Sone H. (2000)
    1088. Induction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell line. (PubMed id 10696073)9 Hukkanen J....Raunio H. (2000)
    1089. 2,3,7,8 Tetrachlorodibenzo-p-dioxin induction of cytochrome P4501A in cultured rat and human hepatocytes. (PubMed id 10728777)9 Xu L....Ruh M.F. (2000)
    1090. Expression of dioxin-related transactivating factors and target genes in human eutopic endometrial and endometriotic tissues. (PubMed id 10764452)9 Bulun S.E....Kilic G. (2000)
    1091. [Applications of aryl hydrocarbon hydroxylase in diagnosis of lung cancer] (PubMed id 11778487)9 Chen L. and Liu Y. (2000)
    1092. Cytochrome P-450 1A1 expression in human small bowel: interindividual variation and inhibition by ketoconazole. (PubMed id 10064566)9 Paine M.F....Watkins P.B. (1999)
    1093. Genetic cancer susceptibility and DNA adducts: studies in smokers, tobacco chewers, and coke oven workers. (PubMed id 10571654)9 Bartsch H....Alexandrov K. (1999)
    1094. Genetic polymorphism of xenobiotic metabolizing enzymes among Chinese lung cancer patients. (PubMed id 10209943)9 Persson I....Ingelman-Sundberg M. (1999)
    1095. Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations. (PubMed id 10454258)9 QuiA+ones L....Lucas D. (1999)
    1096. Quercetin inhibits benzo[a]pyrene-induced DNA adducts in human Hep G2 cells by altering cytochrome P-450 1A1 gene expression. (PubMed id 10693172)9 Kang Z.C....Lee H. (1999)
    1097. Effects of genetic polymorphism of metabolic enzymes, nutrition, and lifestyle factors on DNA adduct formation in lymphocytes. (PubMed id 9810147)9 Wang Y....Tomokuni K. (1998)
    1098. Glutathione S-transferase M1 and T1 and cytochrome P4501A1 polymorphisms in relation to the risk for benign and malignant head and neck lesions. (PubMed id 9486585)9 Oude Ophuis M.B....Manni J.J. (1998)
    1099. Contribution of human hepatic cytochrome P450 isoforms to regioselective hydroxylation of steroid hormones. (PubMed id 9667077)9 Niwa T....Katagiri M. (1998)
    1100. Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile. (PubMed id 9731721)9 MuA+oz S....Chianale J. (1998)
    1101. Delayed ontogenesis of CYP1A2 in the human liver. (PubMed id 9490065)9 Sonnier M. and Cresteil T. (1998)
    1102. 2,3,7,8-Tetrachlorodibenzo-p-dioxin increases mRNA levels for interleukin-1beta, urokinase plasminogen activator, and tumor necrosis factor-alpha in human uterine endometrial adenocarcinoma RL95-2 cells. (PubMed id 9299508)9 Charles G.D. and Shiverick K.T. (1997)
    1103. Effect of transforming growth factor-beta1 on expression of aryl hydrocarbon receptor and genes of Ah gene battery: clues for independent down-regulation in A549 cells. (PubMed id 9145908)9 DAPhr O....Abel J. (1997)
    1104. Cytochrome P450 CYP1A1 MspI polymorphism and lung cancer susceptibility. (PubMed id 8877059)9 Xu X....Christiani D.C. (1996)
    1105. Multiple cutaneous basal cell carcinomas: glutathione S-transferase (GSTM1, GSTT1) and cytochrome P450 (CYP2D6, CYP1A1) polymorphisms influence tumour numbers and accrual. (PubMed id 8824510)9 Lear J.T....Strange R.C. (1996)
    1106. Expression of aryl hydrocarbon receptor (AhR) and aryl hydrocarbon receptor nuclear translocator (Arnt) in adult rabbits known to be non-responsive to cytochrome P-450 1A1 (CYP1A1) inducers. (PubMed id 9022676)9 Takahashi Y....Kamataki T. (1996)
    1107. Bioassay for determining 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEs) in human hepatoma Hepg2 cells. (PubMed id 8920757)9 Wiebel F.J....Kiefer F. (1996)
    1108. Constitutive and inducible expression of drug metabolizing enzymes in cultured human keratinocytes. (PubMed id 7756127)9 Vecchini F....Shroot B. (1995)
    1109. Dioxin-responsive genes: examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction. (PubMed id 8261464)9 Vanden Heuvel J.P....Bell D.A. (1994)
    1110. NAD(P)H:quinone oxidoreductase1 (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase. (PubMed id 8078896)9 Joseph P. and Jaiswal A.K. (1994)
    1111. Effects of cycloheximide on the induction of CYP1A1 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in three human breast cancer cell lines. (PubMed id 8382112)9 Arellano L.O....Safe S. (1993)
    1112. Metabolic cytochrome P450 genotypes and assessment of individual susceptibility to lung cancer. (PubMed id 1306126)9 Hirvonen A....Vainio H. (1992)
    1113. Detection and characterization of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the human colon adenocarcinoma cell line LS180. (PubMed id 1654865)9 Harper P.A....Okey A.B. (1991)
    1114. Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas. (PubMed id 2380990)9 McLemore T.L....Lubet R.A. (1990)
    1115. Induction of cytochrome P(1)450 RNA and benzo[a]pyrene metabolism in primary human hepatocyte cultures with benzanthracene. (PubMed id 1700499)9 Monteith D.K....Strom S.C. (1990)
    1116. Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity. (PubMed id 19903824)9 Murray I.A....Perdew G.H. (2010)
    1117. Exposure of human skin to benzo[a]pyrene: role of CYP 1A1 and aryl hydrocarbon receptor in oxidative stress generation. (PubMed id 20307623)9 Costa C....Melchini A. (2010)
    1118. Peganum harmala L. is a candidate herbal plant for preventing dioxin mediated effects. (PubMed id 19941261)9 El Gendy M.A....El-Kadi A.O. (2010)
    1119. TSU-16, (Z)-3-[(2,4-dimethylpyrrol-5-yl)methylidenyl] -2-indolinone, is a potent activator of aryl hydrocarbon receptor and increases CYP1A1 and CYP1A2 expression in human hepatocytes. (PubMed id 20171196)9 Matsuoka-Kawano K....Yamazoe Y. (2010)
    1120. Evaluation of cytochrome P450 1 (CYP1) and N-acetyltr ansferase 1 (NAT1) activities in HaCaT cells: implications for the development of in vitro techniques for predictive testing of contact sensitizers. (PubMed id 20036732)9 Bonifas J....BlAPmeke B. (2010)
    1121. Activation of the aryl hydrocarbon receptor pathway e nhances cancer cell invasion by upregulating the MMP expression and is associat ed with poor prognosis in upper urinary tract urothelial cancer. (PubMed id 19755661)9 Ishida M....Oya M. (2010)
    1122. The suggested physiologic aryl hydrocarbon receptor activator and cytochrome P4501 substrate 6-formylindolo[3,2-b]carbazole is present in humans. (PubMed id 19054769)9 Wincent E....Rannug U. (2009)
    1123. Inhibition of CYP1A1 by Quassinoids found in Picrasma excelsa. (PubMed id 19016402)9 Shields M....Delgoda R. (2009)
    1124. TCDD-mediated suppression of the in vitro anti-sheep erythrocyte IgM antibody forming cell response is reversed by interferon-gamma. (PubMed id 18948302)9 North C.M....Kaminski N.E. (2009)
    1125. Aryl hydrocarbon receptor pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of matrix metalloproteinase-9. (PubMed id 19371443)9 Peng T.L....Chen M.H. (2009)
    1126. Repression of activated aryl hydrocarbon receptor-induced transcriptional activation by 5alpha-dihydrotestosterone in human prostate cancer LNCaP and human breast cancer T47D cells. (PubMed id 19270430)9 Sanada N....Kizu R. (2009)
    1127. [Metabolic activation of benzo(a)pyrene enhanced tran sformation of human bronchial epithium cell HBETR] (PubMed id 20047213)9 Pang Y....Chen W. (2009)
    1128. Activation function 2 mediates dioxin-induced recruit ment of estrogen receptor alpha to CYP1A1 and CYP1B1. (PubMed id 19460354)9 MacPherson L....Matthews J. (2009)
    1129. Modulation of carcinogen metabolism by nitric oxide-a spirin 2 is associated with suppression of DNA damage and DNA adduct formation. (PubMed id 19542225)9 MacDonald C.J....Yeh G.C. (2009)
    1130. Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen. (PubMed id 19462483)9 Teksin Z.S....Eddington N.D. (2009)
    1131. Effects of dioxin on vascular endothelial growth fact or (VEGF) production in the retina associated with choroidal neovascularization . (PubMed id 19182260)9 Takeuchi A....Kuroda M. (2009)
    1132. Further assessment of 17alpha-ethinyl estradiol as an inhibitor of different human cytochrome P450 forms in vitro. (PubMed id 19454483)9 Chang S.Y....Rodrigues A.D. (2009)
    1133. 3-aminobenzanthrone, a human metabolite of the carcin ogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation e nzymes in rat kidney and lung. (PubMed id 19398038)9 StiborovA! M....Arlt V.M. (2009)
    1134. Cytochrome P450 CYP1A1: wider roles in cancer progres sion and prevention. (PubMed id 19531241)9 Androutsopoulos V.P....Spandidos D.A. (2009)
    1135. Up-regulation of the CYP1 family in rat and human liv er by the aliphatic isothiocyanates erucin and sulforaphane. (PubMed id 18773935)9 Hanlon N....Ioannides C. (2008)
    1136. 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates the induction of DNA strand breaks and poly(ADP-ribose) polymerase-1 activation by 17beta-estradiol in human breast carcinoma cells through alteration of CYP1A1 and CYP1B1 expression. (PubMed id 18558727)9 Lin P.H....Chuang M.C. (2008)
    1137. Effect of long-term selenium yeast intervention on activity and gene expression of antioxidant and xenobiotic metabolising enzymes in healthy elderly volunteers from the Danish Prevention of Cancer by Intervention by Selenium (PRECISE) pilot study. (PubMed id 18062829)9 Ravn-Haren G....Dragsted L.O. (2008)
    1138. Activation of the aryl hydrocarbon receptor by the calcium/calmodulin-dependent protein kinase kinase inhibitor 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid (STO-609). (PubMed id 18755850)9 Monteiro P....Fardel O. (2008)
    1139. Pyrethroids: cytotoxicity and induction of CYP isoforms in human hepatocytes. (PubMed id 19326768)9 Das P.C....Hodgson E. (2008)
    1140. Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor. (PubMed id 18814841)9 Shi Z....Nebert D.W. (2008)
    1141. Tumor necrosis factor-alpha potentiates genotoxic effects of benzo[a]pyrene in rat liver epithelial cells through upregulation of cytochrome P450 1B1 expression. (PubMed id 18336843)9 UmannovA! L....VondrA!cek J. (2008)
    1142. The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers. (PubMed id 18172554)9 Zudaire E....Cuttitta F. (2008)
    1143. A low halogenated biphenyl (PCB3) increases CYP1A1 expression and activity via the estrogen receptor beta in the porcine ovary. (PubMed id 18953099)9 Ptak A....Gregoraszczuk E.A.8. (2008)
    1144. A novel synthetic analogue of a constituent of Isodon excisus inhibits transcription of CYP1A1, -1A2 and -1B1 by preventing activation of the aryl hydrocarbon receptor. (PubMed id 17183067)9 Sienkiewicz P....Yeh G.C. (2007)
    1145. Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. (PubMed id 17682057)9 Schnekenburger M....Puga A. (2007)
    1146. The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis. (PubMed id 17376491)9 Knaapen A.M....Van Schooten F.J. (2007)
    1147. Cytochrome P450 expression (CYP) in non-small cell lung cancer. (PubMed id 17127240)9 Oyama T....Yasumoto K. (2007)
    1148. Identification of a novel co-transcription of P450/1A1 with telomerase in A549. (PubMed id 17141429)9 Shervington A....Lea R. (2007)
    1149. A possible role for dihydrodiol dehydrogenase in the formation of benzo[a]pyrene-DNA adducts in lung cancer cells and tumor tissues. (PubMed id 17163506)9 Cheng Y.W....Lee H. (2007)
    1150. Cyclooxygenase-2 promoter activation by the aromatic hydrocarbon receptor in breast cancer mcf-7 cells: repressive effects of conjugated linoleic acid. (PubMed id 18001219)9 Degner S.C....Romagnolo D.F. (2007)
    1151. Eugenol inhibit 7,12-dimethylbenz[a]anthracene-induced genotoxicity in MCF-7 cells: Bifunctional effects on CYP1 and NAD(P)H:quinone oxidoreductase. (PubMed id 17275817)9 Han E.H....Jeong H.G. (2007)
    1152. A dioxin-responsive enhancer 3' of the human CYP1A2 gene. (PubMed id 17785579)9 Okino S.T....Dahiya R. (2007)
    1153. Cytochrome P450 gene induction in rats ex vivo assess ed by quantitative real-time reverse transcriptase-polymerase chain reaction (T aqMan). (PubMed id 16531474)9 Baldwin S.J....Clarke S.E. (2006)
    1154. Inhibition of benzo[a]pyrene-activating enzymes and DNA binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids. (PubMed id 16484233)9 Tsuji P.A. and Walle T. (2006)
    1155. Influence of glutathione-S-transferase (GSTM1, GSTP1, GSTT1) and cytochrome p450 (CYP1A1, CYP2D6) polymorphisms on numbers of basal cell carcinomas (BCCs) in families with the naevoid basal cell carcinoma syndrome. (PubMed id 16582078)9 R Yang X....Goldstein A.M. (2006)
    1156. Naphthalene toxicity in mice and aryl hydrocarbon rec eptor-mediated CYPs. (PubMed id 16876762)9 Genter M.B....Nebert D.W. (2006)
    1157. TCDD-induced CYP1A1 expression, an index of dioxin toxicity, is suppressed by flavonoids permeating the human intestinal Caco-2 cell monolayers. (PubMed id 17090139)9 Hamada M....Shimizu M. (2006)
    1158. Arsenic inhibits induction of cytochrome P450 1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin in human hepatoma cells. (PubMed id 16713074)9 Chao H.R....Lee W.J. (2006)
    1159. Preferential induction of CYP1A1 and CYP1B1 in CCSP-positive cells. (PubMed id 16237193)9 Chang H....Lin P. (2006)
    1160. Oxidative metabolism of the alkaloid rutaecarpine by human cytochrome P450. (PubMed id 16501007)9 Ueng Y.F....Chen C.F. (2006)
    1161. Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture standard reference material 1649a. (PubMed id 15735009)9 Mahadevan B....Baird W.M. (2005)
    1162. ER alpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription. (PubMed id 15837795)9 Beischlag T.V. and Perdew G.H. (2005)
    1163. Tissue-distribution of aldehyde dehydrogenase 2 and effects of the ALDH2 gene-disruption on the expression of enzymes involved in alcohol metabolism. (PubMed id 15569633)9 Oyama T....Kawamoto T. (2005)
    1164. Vinclozolin, a widely used fungizide, enhanced BaP-induced micronucleus formation in human derived hepatoma cells by increasing CYP1A1 expression. (PubMed id 15979257)9 Wu X.J....Mersch-Sundermann V. (2005)
    1165. Gene expression changes in human small airway epithelial cells exposed to Delta9-tetrahydrocannabinol. (PubMed id 16039398)9 Sarafian T....Roth M.D. (2005)
    1166. Long-term effects of a standardized complex mixture of urban dust particulate on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture. (PubMed id 16162842)9 Musafia-Jeknic T....Baird W.M. (2005)
    1167. Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice. (PubMed id 15970798)9 Derkenne S....Nebert D.W. (2005)
    1168. Herbicide resistance in transgenic plants with mammalian P450 monooxygenase genes. (PubMed id 15660356)9 Inui H. and Ohkawa H. (2005)
    1169. [Feasibility of genetic polymorphisms analysis using genomic DNA obtained from human buccal cells] (PubMed id 16004823)9 Cheng J.R....Gao Y.T. (2005)
    1170. Role of coactivators in transcriptional activation by the aryl hydrocarbon receptor. (PubMed id 15581594)9 Hankinson O. (2005)
    1171. Activation of the aryl hydrocarbon receptor by berberine in HepG2 and H4IIE cells: Biphasic effect on CYP1A1. (PubMed id 16046213)9 Vrzal R....DvorA!k Z. (2005)
    1172. Lack of CYP1A1 expression is involved in unresponsiveness of the human hepatoma cell line SK-HEP-1 to dioxin. (PubMed id 16054781)9 Shiizaki K....Tohyama C. (2005)
    1173. Preferential induction of CYP1B1 by benzo[a]pyrene in human oral epithelial cells: impact on DNA adduct formation and prevention by polyphenols. (PubMed id 15905203)9 Wen X. and Walle T. (2005)
    1174. Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast. (PubMed id 15507517)9 Dubey R.K....Imthurn B. (2005)
    1175. Role of estrogen receptor in regulation of polycyclic aromatic hydrocarbon metabolic activation in lung. (PubMed id 15301869)9 Berge G....Haugen A. (2004)
    1176. Inhibition of the MEK-1/p42 MAP kinase reduces aryl hydrocarbon receptor-DNA interactions. (PubMed id 15313166)9 Yim S....Park H. (2004)
    1177. Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives. (PubMed id 15081870)9 Sparfel L....Fardel O. (2004)
    1178. Induction of gene expression of xenobiotic metabolism enzymes and ABC-transport proteins by PAH and a reconstituted PAH mixture in human Caco-2 cells. (PubMed id 15566942)9 Lampen A....Seidel A. (2004)
    1179. CYP1B1 expression in prostate is higher in the peripheral than in the transition zone. (PubMed id 15374634)9 Ragavan N....Martin F.L. (2004)
    1180. Genotoxic profiling of MCF-7 breast cancer cell line elucidates gene expression modifications underlying toxicity of the anticancer drug 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole. (PubMed id 12606787)9 Monks A....Sausville E.A. (2003)
    1181. Antagonism of aryl hydrocarbon receptor-dependent induction of CYP1A1 and inhibition of IgM expression by di-ortho-substituted polychlorinated biphenyls. (PubMed id 12628580)9 Suh J....Kaminski N.E. (2003)
    1182. DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells. (PubMed id 12592376)9 Trapani V....Loaiza-Perez A.I. (2003)
    1183. Quantitation of CYP1A1 and 1B1 mRNA in polycyclic aromatic hydrocarbon-treated human T-47D and HepG2 cells by a modified bDNA assay using fluorescence detection. (PubMed id 12531201)9 Wu S.J....Kaminsky L.S. (2003)
    1184. Hypogonadotropic hypogonadism as a model of post-natal testicular anti-Mullerian hormone secretion in humans. (PubMed id 14656476)9 Young J....Chanson P. (2003)
    1185. Effects of dimethyl sulfoxide on the gene induction of cytochrome P450 isoforms, UGT-dependent glucuronosyl transferase isoforms, and ABCB1 in primary culture of human hepatocytes. (PubMed id 12843640)9 Nishimura M....Naito S. (2003)
    1186. Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex. (PubMed id 11805098)9 Wang S. and Hankinson O. (2002)
    1187. Baicalein inhibits DMBA-DNA adduct formation by modulating CYP1A1 and CYP1B1 activities. (PubMed id 12224597)9 Chan H.Y....Leung L.K. (2002)
    1188. CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism. (PubMed id 11960914)9 Godoy W....Pinto L.F. (2002)
    1189. CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation. (PubMed id 12507920)9 Alexandrov K....Bartsch H. (2002)
    1190. Ligand-dependent and independent modulation of aryl hydrocarbon receptor localization, degradation, and gene regulation. (PubMed id 12237327)9 Song Z. and Pollenz R.S. (2002)
    1191. In vitro effect of standardized ginseng extracts and individual ginsenosides on the catalytic activity of human CYP1A1, CYP1A2, and CYP1B1. (PubMed id 11901090)9 Chang T.K....Benetton S.A. (2002)
    1192. Species differences in the distribution of drug-metabolizing enzymes in the pancreas. (PubMed id 11950168)9 Ulrich A.B....Pour P.M. (2002)
    1193. Expression of AhR and ARNT mRNA in cultured human endometrial explants exposed to TCDD. (PubMed id 11452142)9 Pitt J.A....Bofinger D.P. (2001)
    1194. Physiological modeling of a proposed mechanism of enz yme induction by TCDD. (PubMed id 11369115)9 Kohn M.C....Portier C.J. (2001)
    1195. Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol. (PubMed id 11555828)9 Badawi A.F....Rogan E.G. (2001)
    1196. Green fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio). (PubMed id 11564622)9 Mattingly C.J....Toscano W.A. (2001)
    1197. Smoking, genetic polymorphisms in biotransformation enzymes, and nonsyndromic oral clefting: a gene-environment interaction. (PubMed id 11505167)9 van Rooij I.A....Steegers-Theunissen R.P. (2001)
    1198. Dibenzoylmethane modulates aryl hydrocarbon receptor function and expression of cytochromes P50 1A1, 1A2, and 1B1. (PubMed id 11358806)9 MacDonald C.J....Yeh G.C. (2001)
    1199. Pharmacogenetic profile of xenobiotic enzyme metabolism in survivors of the Spanish toxic oil syndrome. (PubMed id 11335185)9 Ladona M.G....Sanz E.J. (2001)
    1200. Serum induces a transcriptional activation of CYP1A1 gene in HepG2 independently of the AhR pathway. (PubMed id 11324719)9 Guigal N....Barra Y. (2001)
    1201. Role of human cytochrome P450 (CYP) in the metabolic activation of N-alkylnitrosamines: application of genetically engineered Salmonella typhimurium YG7108 expressing each form of CYP together with human NADPH-cytochrome P450 reductase. (PubMed id 11600130)9 Fujita K. and Kamataki T. (2001)
    1202. Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines. (PubMed id 11507062)9 Bonnesen C....Hayes J.D. (2001)
    1203. Modulation of cytochrome P4501-mediated bioactivation of benzo[a]pyrene by volatile allyl sulfides in human hepatoma cells. (PubMed id 11758911)9 Chun H.S....Choi E.H. (2001)
    1204. Structure and expression of the Ah receptor repressor gene. (PubMed id 11423533)9 Baba T....Fujii-Kuriyama Y. (2001)
    1205. The effect of community-acquired pneumonia on plasma esterases in older people. (PubMed id 11372593)9 Abou-Hatab K....Woodhouse K. (2001)
    1206. Predicting the mutagenicity of tobacco-related N-nitrosamines in humans using 11 strains of Salmonella typhimurium YG7108, each coexpressing a form of human cytochrome P450 along with NADPH-cytochrome P450 reductase. (PubMed id 11774366)9 Fujita K. and Kamataki T. (2001)
    1207. Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations. (PubMed id 11323399)9 Nan H.M....Kwon E.H. (2001)
    1208. Diflubenzuron, a benzoyl-urea insecticide, is a potent inhibitor of TCDD-induced CYP1A1 expression in HepG2 cells. (PubMed id 10799337)9 Ledirac N....Rahmani R. (2000)
    1209. CYP1A1 polymorphisms and lung cancer risk: a meta-analysis. (PubMed id 10761998)9 Houlston R.S. (2000)
    1210. The effect of the genetic polymorphisms of CYP1A1,CYP2D6, GSTM1 and GSTP1 on aromatic DNA adduct levels in the population of healthy women. (PubMed id 10984688)9 Grzybowska E....Chorazy M. (2000)
    1211. The human cytochrome P450 1A1 mRNA is rapidly degraded in HepG2 cells. (PubMed id 11368318)9 Lekas P....Prokipcak R.D. (2000)
    1212. Rapid determination of rat hepatocyte mRNA induction potential using oligonucleotide probes for CYP1A1, 1A2, 3A and 4A1. (PubMed id 10875679)9 Surry D.D....Evans D.C. (2000)
    1213. Identification of cytochrome P450 isoform involved in the metabolism of YM992, a novel selective serotonin re-uptake inhibitor, in human liver microsomes. (PubMed id 10875683)9 Noguchi K....Chiba K. (2000)
    1214. Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP1A gene expression. (PubMed id 11064004)9 Williams S.N....Quattrochi L.C. (2000)
    1215. Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma. (PubMed id 10732758)9 Lin P....Lee H. (2000)
    1216. Human cytochrome P-450 metabolism of retinals to retinoic acids. (PubMed id 10681373)9 Zhang Q.Y....Kaminsky L. (2000)
    1217. Genetic polymorphisms of CYP2D6, CYP1A1, GSTM1 and p53 genes in a unique Siberian population of Tundra Nentsi. (PubMed id 10975607)9 Duzhak T....Lyakhovich V.V. (2000)
    1218. Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes. (PubMed id 10873607)9 Runge D....Michalopoulos G.K. (2000)
    1219. Colorectal cancer risk in relation to genetic polymorphism of cytochrome P450 1A1, 2E1, and glutathione-S-transferase M1 enzymes. (PubMed id 10769717)9 Kiss I....Ember I. (2000)
    1220. Role of estradiol metabolism and CYP1A1 polymorphisms in breast cancer risk. (PubMed id 10337002)9 Taioli E....Garte S.J. (1999)
    1221. Cytochromes P450 are expressed in proliferating cells in Barrett's metaplasia. (PubMed id 10933049)9 Hughes S.J....Beer D.G. (1999)
    1222. Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol. (PubMed id 10496959)9 Ciolino H.P. and Yeh G.C. (1999)
    1223. Induction of hepatic cytochromes P450 in dogs exposed to a chronic low dose of polychlorinated biphenyls. (PubMed id 10048153)9 Korytko P.J....Quimby F.W. (1999)
    1224. Candidate genetic modifiers of individual susceptibility to renal cell carcinoma: a study of polymorphic human xenobiotic-metabolizing enzymes. (PubMed id 10383153)9 Longuemaux S....Dupret J.M. (1999)
    1225. Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms. (PubMed id 10029576)9 Krajinovic M....Sinnett D. (1999)
    1226. Prediction of human liver microsomal oxidations of 7-ethoxycoumarin and chlorzoxazone with kinetic parameters of recombinant cytochrome P-450 enzymes. (PubMed id 10534312)9 Shimada T....Yamazaki H. (1999)
    1227. Prevalence of disease-related DNA polymorphisms among participants in a large cancer prevention trial. (PubMed id 10548400)9 Woodson K....Albanes D. (1999)
    1228. Polymorphic expression of the glutathione S-transferase P1 gene and its susceptibility to Barrett's esophagus and esophageal carcinoma. (PubMed id 9973204)9 van Lieshout E.M....Peters W.H. (1999)
    1229. GSTM1, GSTP1, CYP1A1 and CYP2D6 polymorphisms in lung cancer patients from an environmentally polluted region of Poland: correlation with lung DNA adduct levels. (PubMed id 10493307)9 Butkiewicz D....Chorazy M. (1999)
    1230. Cytochrome P4501A1 polymorphism as a susceptibility factor for breast cancer in postmenopausal Chinese women in Taiwan. (PubMed id 10468307)9 Huang C.S....Chern H.D. (1999)
    1231. Species differences in hepatocyte induction of CYP1A1 and CYP1A2 by omeprazole. (PubMed id 10100022)9 Shih H....Quattrochi L.C. (1999)
    1232. AhR, ARNT, and CYP1A1 mRNA quantitation in cultured human embryonic palates exposed to TCDD and comparison with mouse palate in vivo and in culture. (PubMed id 10048154)9 Abbott B.D....Schmid J. (1999)
    1233. Study of the frequencies of CYP1A1 gene polymorphisms and glutathione S-transferase mu1 gene in primary breast cancers: an update with an additional 114 cases. (PubMed id 9726005)9 Fontana X....BussiA"re F. (1998)
    1234. Aryl hydrocarbon receptor-dependent suppression by 2,3,7, 8-tetrachlorodibenzo-p-dioxin of IgM secretion in activated B cells. (PubMed id 9547351)9 Sulentic C.E....Kaminski N.E. (1998)
    1235. Rapid and transient induction of CYP1A1 gene expression in human cells by the tryptophan photoproduct 6-formylindolo[3,2-b]carbazole. (PubMed id 9566724)9 Wei Y.D....Rannug A. (1998)
    1236. Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues. (PubMed id 9797707)9 Mace K....Pfeifer A.M. (1998)
    1237. 12-O-tetradecanoylphorbol-13-acetate upregulates the Ah receptor and differentially alters CYP1B1 and CYP1A1 expression in MCF-7 breast cancer cells. (PubMed id 9706865)9 Spink B.C....Spink D.C. (1998)
    1238. Development of a non-high pressure liquid chromatography assay to determine [14C]chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes. (PubMed id 9531516)9 Draper A.J....Parkinson A. (1998)
    1239. Effect of curcumin on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells. (PubMed id 9698073)9 Ciolino H.P....Yeh G.C. (1998)
    1240. An expressional system of human cytochrome P-450 CYP1A1 gene transcription. (PubMed id 10375802)9 Wang H....Peng R.X. (1998)
    1241. Modulation of DNA adduct levels in human mononuclear white blood cells and granulocytes by CYP1A1 CYP2D6 and GSTM1 genetic polymorphisms. (PubMed id 9711266)9 Butkiewicz D....Chorazy M. (1998)
    1242. p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer. (PubMed id 9918134)9 Przygodzki R.M....Caporaso N.E. (1998)
    1243. Genetic polymorphisms in glutathione S-transferase mu and theta, N-acetyltransferase, and CYP1A1 and risk of gliomas. (PubMed id 9641501)9 Trizna Z....Bondy M.L. (1998)
    1244. Susceptibility and outcome in oral cancer: preliminary data showing an association with polymorphism in cytochrome P450 CYP2D6. (PubMed id 9825835)9 Worrall S.F....Strange R.C. (1998)
    1245. Hypoxia and CYP1A1 induction-dependent regulation of proteins involved in glucose utilization in Caco-2 cells. (PubMed id 9696711)9 CarriA"re V....Rousset M. (1998)
    1246. Catalytic activities, protein- and mRNA-expression of cytochrome P450 isoenzymes in intestinal cell lines. (PubMed id 9622846)9 Lampen A....Borlak J.T. (1998)
    1247. In vitro metabolism of 7,12-dimethylbenz[a]anthracene by rainbow trout liver microsomes and trout P450 isoforms. (PubMed id 9007041)9 Miranda C.L....Buhler D.R. (1997)
    1248. Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and human esophageal squamous cell carcinoma susceptibility. (PubMed id 9451664)9 Hori H....Yuasa Y. (1997)
    1249. Upstream stimulatory factor 1 (USF1) suppresses induction of CYP1A1 mRNA by 3-methylcholanthrene (MC) in HepG2 cells. (PubMed id 9388470)9 Takahashi Y....Kamataki T. (1997)
    1250. CYP1A1, CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous-cell carcinoma of the esophagus. (PubMed id 9139841)9 Morita S....Monden M. (1997)
    1251. Glucocorticoid potentiation of cytochrome P4501A1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin in porcine and human endothelial cells in culture. (PubMed id 9126348)9 Celander M....Stegeman J.J. (1997)
    1252. Stable expression of human cytochrome CYP2B6 and CYP1A1 in Chinese hamster CHL cells: their use in micronucleus assays. (PubMed id 11360624)9 Wu J....Yu Y. (1997)
    1253. CYP1A1 and GSTM1 polymorphisms and oral cancer risk. (PubMed id 9332761)9 Park J.Y....Lazarus P. (1997)
    1254. Benzo(a)pyrene, but not 2,3,7,8-tetrachlorodibenzo-p-dioxin, alters cell proliferation and c-myc and growth factor expression in human placental choriocarcinoma JEG-3 cells. (PubMed id 9070231)9 Zhang L. and Shiverick K.T. (1997)
    1255. Validation of precision-cut liver slices in dynamic organ culture as an in vitro model for studying CYP1A1 and CYP1A2 induction. (PubMed id 8887457)9 Drahushuk A.T....Olson J.R. (1996)
    1256. Identification of a cell-specific transcription activation domain within the human Ah receptor nuclear translocator. (PubMed id 8806843)9 Corton J.C....Kennett S.B. (1996)
    1257. Development of human cytochrome P450-expressing cell lines: application in mutagenicity testing of ochratoxin A. (PubMed id 8542584)9 de Groene E.M....Horbach G.J. (1996)
    1258. Protein kinase C modulates regulation of the CYP1A1 gene by the aryl hydrocarbon receptor. (PubMed id 8824276)9 Chen Y.H. and Tukey R.H. (1996)
    1259. Correlation between P450 CYP1A1 inducibility, MspI genotype and lung cancer incidence. (PubMed id 8983277)9 Jacquet M....Gielen J. (1996)
    1260. Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1A1: a CO flash photolysis study. (PubMed id 8954573)9 Koley A.P....Friedman F.K. (1996)
    1261. Cytochrome P450 mediated reactions studied in genetically engineered V79 Chinese hamster cells. (PubMed id 7581497)9 Doehmer J....Jacob J. (1995)
    1262. Effect of a negative regulatory element (NRE) on the human CYP1A1 gene expression in breast carcinoma MCF-7 and hepatoma HepG2 cells. (PubMed id 7781760)9 JA...Autrup H. (1995)
    1263. Inhibition of benzo[a]pyrene metabolism by insulin, FITC-insulin and an FITC-insulin-antibody conjugate in the human hepatoma cell line HepG2. (PubMed id 7671346)9 Polzer R.J....Baird W.M. (1995)
    1264. Expression of cytochrome P450 and microsomal epoxide hydrolase in cervical and oral epithelial cells immortalized by human papillomavirus type 16 E6/E7 genes. (PubMed id 7788860)9 Farin F.M....Omiecinski C.J. (1995)
    1265. [Application of molecular biology to occupational health field--the frequency of gene polymorphism of cytochrome P450 1A1 and glutathione S-transferase M1 in patients with lung, oral and urothelial cancer] (PubMed id 8552885)9 Katoh T. (1995)
    1266. Multiple forms of cytochrome P450 are involved in the metabolism of ondansetron in humans. (PubMed id 8591723)9 Dixon C.M....Tarbit M.H. (1995)
    1267. Phenotypic variability in induction of P-glycoprotein mRNA by aromatic hydrocarbons in primary human hepatocytes. (PubMed id 7662117)9 Schuetz E.G....Strom S.C. (1995)
    1268. Cytochrome P4501A1 and glutathione S-transferase (M1) genetic polymorphisms and postmenopausal breast cancer risk. (PubMed id 7627950)9 Ambrosone C.B....Harrington A. (1995)
    1269. Different response of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-sensitive genes in human breast cancer MCF-7 and MDA-MB 231 cells. (PubMed id 7646066)9 DAPhr O....Abel J. (1995)
    1270. Association between CYP1A1 genotype, mRNA expression and enzymatic activity in humans. (PubMed id 7894496)9 Landi M.T....Caporaso N.E. (1994)
    1271. Hepatic uptake and metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzofuran. (PubMed id 8056209)9 Olson J.R....McReynolds J.H. (1994)
    1272. Interindividual difference in expression of human Ah receptor and related P450 genes. (PubMed id 7515333)9 Hayashi S.... Kawajiri K. (1994)
    1273. Presence of a retinoid responsive element in the prom oter region of the human cytochrome P4501A1 gene. (PubMed id 8024563)9 Vecchini F....Shroot B. (1994)
    1274. Down-regulation of P4501A1 and P4501A2 mRNA expression in isolated hepatocytes by oxidative stress. (PubMed id 8307954)9 Barker C.W....Pasco D.S. (1994)
    1275. Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver. (PubMed id 8093105)9 Burke M.D....Mayer R.T. (1994)
    1276. Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1: a study on host factors in relation to age at onset, gender and histological cancer types. (PubMed id 7923570)9 Alexandrie A.K....Rannug A. (1994)
    1277. Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction. (PubMed id 8395783)9 Nebert D.W....Vasiliou V. (1993)
    1278. The CYP1A1 gene and cancer susceptibility. (PubMed id 8103989)9 Kawajiri K....Hayashi S. (1993)
    1279. Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer. (PubMed id 8389669)9 Kawajiri K....Hayashi S. (1993)
    1280. Immunohistochemical detection of pulmonary cytochrome P450IA and metabolic activities associated with P450IA1 and P450IA2 isozymes i n lung cancer patients. (PubMed id 1336724)9 Anttila S....Bartsch H. (1992)
    1281. Caffeine as a probe for human cytochromes P450: validation using cDNA-expression, immunoinhibition and microsomal kinetic and inhibitor techniques. (PubMed id 1306118)9 Tassaneeyakul W....Miners J.O. (1992)
    1282. Genetic polymorphism of cytochromes P450: interethnic differences and relationship to incidence of lung cancer. (PubMed id 1306127)9 Ingelman-Sundberg M....SjAPqvist F. (1992)
    1283. Induction of CYP1A1 mRNA in rat epidermis and cultured human epidermal keratinocytes by benz(a)anthracene and beta-naphthoflavone. (PubMed id 1358564)9 Khan I.U....Mukhtar H. (1992)
    1284. Increased smooth muscle cell proliferation by dimethylbenzanthracene is correlated to variations in activity of ornithine decarboxylase but not arylhydrocarbonhydroxylase. (PubMed id 1929884)9 Pessah-Rasmussen H....Berglund A. (1991)
    1285. Carcinogen metabolism and DNA adducts in human lung tissues as affected by tobacco smoking or metabolic phenotype: a case-control study on lung cancer patients. (PubMed id 1944327)9 Bartsch H....Giuntini C. (1991)
    1286. Differences in 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible CYP1A1 expression in human breast carcinoma cell lines involve altered trans-acting factors. (PubMed id 2029891)9 Thomsen J.S....Autrup H. (1991)
    1287. Ultraviolet photoproducts of tryptophan can act as dioxin agonists. (PubMed id 1658604)9 Helferich W.G. and Denison M.S. (1991)
    1288. In vitro effects of methylsulfonyl polychlorinated biphenyls and 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity in human lymphoblastoid cells. (PubMed id 2115161)9 Kiyohara C....Masuda Y. (1990)
    1289. Differential action of chlorinated polycyclic aromati c hydrocarbons on aryl hydrocarbon receptor-mediated signaling in breast cancer cells. (PubMed id 19365803)9 Ohura T....Shimoi K. (2010)
    1290. Estradiol-17beta and its cytochrome P450- and catecho l-O-methyltransferase-derived metabolites stimulate proliferation in uterine ar tery endothelial cells: role of estrogen receptor-alpha versus estrogen recepto r-beta. (PubMed id 20212268)9 Jobe S.O....Magness R.R. (2010)
    1291. Modulation of carcinogen-metabolising cytochromes P45 0 in human liver by the chemopreventive phytochemical phenethyl isothiocyanate, a constituent of cruciferous vegetables. (PubMed id 20025923)9 Konsue N. and Ioannides C. (2010)
    1292. A methoxyflavonoid, chrysoeriol, selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cel ls. (PubMed id 19833205)9 Takemura H....Shimoi K. (2010)
    1293. Cytochromes P4501 (CYP1): catalytic activities and in ducibility by diesel exhaust particle extract and benzo[a]pyrene in intact huma n lung ex vivo. (PubMed id 20435083)9 Iba M.M....Caccavale R.J. (2010)
    1294. Neurogenic-committed human pre-adipocytes express CYP 1A isoforms. (PubMed id 20080079)9 Scanarotti C....Raposio E. (2010)
    1295. Diminished carcinogen detoxification is a novel mecha nism for hypoxia-inducible factor 1-mediated genetic instability. (PubMed id 20228066)9 Schults M.A....Chiu R.K. (2010)
    1296. 3-Methylindole metabolites induce lung CYP1A1 and CYP 2F1 enzymes by AhR and non-AhR mechanisms, respectively. (PubMed id 20187624)9 Weems J.M. and Yost G.S. (2010)
    1297. Effects of beta-carotene supplementation on molecular markers of lung carcinogenesis in male smokers. (PubMed id 20484175)9 Wright M.E....Albanes D. (2010)
    1298. Air pollution particulate matter (PM2.5)-induced gene expression of volatile organic compound and/or polycyclic aromatic hydrocarbon-metabolizing enzymes in an in vitro coculture lung model. (PubMed id 18952161)9 Abbas I....GarAson G. (2009)
    1299. CYP1A1 and CYP3A4 modulation by dietary flavonoids in human intestinal Caco-2 cells. (PubMed id 19766177)9 Sergent T....Schneider Y.J. (2009)
    1300. Modulation of aflatoxin B1-mediated genotoxicity in p rimary cultures of human hepatocytes by diindolylmethane, curcumin, and xanthoh umols. (PubMed id 19770484)9 Gross-Steinmeyer K....Eaton D.L. (2009)
    1301. Fatty acid hydroperoxides support cytochrome P450 2S1 -mediated bioactivation of benzo[a]pyrene-7,8-dihydrodiol. (PubMed id 19713357)9 Bui P.H....Hankinson O. (2009)
    1302. Long-term estrogen exposure promotes carcinogen bioac tivation, induces persistent changes in gene expression, and enhances the tumor igenicity of MCF-7 human breast cancer cells. (PubMed id 19619570)9 Spink B.C....Spink D.C. (2009)
    1303. Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations. (PubMed id 19682468)9 Bendaly J....Hein D.W. (2009)
    1304. Expression of cytochrome P450 (CYP) enzymes in human nonpigmented ciliary epithelial cells: induction of CYP1B1 expression by TCDD. (PubMed id 19324859)9 Volotinen M....Hakkola J. (2009)
    1305. Evaluation of molecular markers in a rat model of mam mary carcinogenesis. (PubMed id 19725228)9 Vinothini G....Nagini S. (2009)
    1306. Ligand selectivity and gene regulation by the human a ryl hydrocarbon receptor in transgenic mice. (PubMed id 19299563)9 Flaveny C.A....Perdew G.H. (2009)
    1307. The role of biotransformation enzymes in the developm ent of renal injury and urothelial cancer caused by aristolochic acid: urgent q uestions and difficult answers. (PubMed id 19365519)9 Stiborova M....Schmeiser H.H. (2009)
    1308. 3-Nitrofluoranthene (3-NF) but not 3-aminofluoranthene (3-AF) elicits apoptosis as well as programmed necrosis in Hepa1c1c7 cells. (PubMed id 19041363)9 Asare N....Holme J.A. (2009)
    1309. Weight of evidence evaluation of potential human canc er risks from exposure to polychlorinated biphenyls: an update based on studies published since 2003. (PubMed id 19514916)9 Golden R. and Kimbrough R. (2009)
    1310. PCB126 enhanced the genotoxicity of BaP in HepG2 cell s by modulating metabolic enzyme and DNA repair activities. (PubMed id 19553035)9 Wei W....Lu W.Q. (2009)
    1311. The methoxylated flavones eupatorin and cirsiliol ind uce CYP1 enzyme expression in MCF7 cells. (PubMed id 19601638)9 Androutsopoulos V.P....Arroo R.R. (2009)
    1312. Effect of PCB153 on BaP-induced genotoxicity in HepG2 cells via modulation of metabolic enzymes. (PubMed id 19386251)9 Wei W....Lu W.Q. (2009)
    1313. Sulforaphane and its analogues inhibit CYP1A1 and CYP1A2 activity induced by benzo[a]pyrene. (PubMed id 19202560)9 Skupinska K....Kasprzycka-Guttman T. (2009)
    1314. Novel metabolites of amodiaquine formed by CYP1A1 and CYP1B1: structure elucidation using electrochemistry, mass spectrometry, and NMR. (PubMed id 19074972)9 Johansson T....Masimirembwa C. (2009)
    1315. Toxic and chemopreventive ligands preferentially activate distinct aryl hydrocarbon receptor pathways: implications for cancer prevention. (PubMed id 19223575)9 Okino S.T....Dahiya R. (2009)
    1316. Aryl hydrocarbon receptor inhibition downregulates th e TGF-beta/Smad pathway in human glioblastoma cells. (PubMed id 19465936)9 Gramatzki D....Tritschler I. (2009)
    1317. Cytotoxicity of and DNA adduct formation by elliptici ne in human U87MG glioblastoma cancer cells. (PubMed id 20027146)9 Martinkova E....Stiborova M. (2009)
    1318. Activation of MAPKs influences the expression of drug -metabolizing enzymes in primary human hepatocytes. (PubMed id 20037198)9 Bachleda P....DvorA!k Z. (2009)
    1319. Modulation of benzo[a]pyrene induced immunotoxicity i n mice actively immunized with a B[a]P-diphtheria toxoid conjugate. (PubMed id 19573549)9 Schellenberger M.T....Muller C.P. (2009)
    1320. Biological markers of carcinogenic exposure in the al uminum smelter industry--a systematic review. (PubMed id 19629825)9 Hopf N.B....Talaska G. (2009)
    1321. [Genetic base of esophageal squamous cell carcinoma susceptibility] (PubMed id 19388510)9 SzumiA8o J....Burdan F. (2009)
    1322. Modulation of CYP1B1 and CYP1A1 gene expression and a ctivation of aryl hydrocarbon receptor by Ginkgo biloba extract in MCF-10A huma n mammary epithelial cells. (PubMed id 19794518)9 Rajaraman G....Chang T.K. (2009)
    1323. Genistein protects against polycyclic aromatic hydroc arbon-induced oxidative DNA damage in non-cancerous breast cells MCF-10A. (PubMed id 18570695)9 Leung H.Y....Leung L.K. (2009)
    1324. Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes. (PubMed id 19022236)9 Vrzal R....Dvorak Z. (2009)
    1325. Polymorphism of human cytochrome P450 enzymes and its clinical impact. (PubMed id 19514967)9 Zhou S.F....Chowbay B. (2009)
    1326. The genomics of oral cancer and wound healing. (PubMed id 19414966)9 Aswini Y.B. (2009)
    1327. The effect of isothiocyanates on CYP1A1 and CYP1A2 ac tivities induced by polycyclic aromatic hydrocarbons in Mcf7 cells. (PubMed id 19362136)9 Skupinska K....Kasprzycka-Guttman T. (2009)
    1328. Examination of Zolpidem effects on AhR- and PXR-depen dent expression of drug-metabolizing cytochromes P450 in primary cultures of hu man hepatocytes. (PubMed id 19686824)9 Bachleda P....Dvorak Z. (2009)
    1329. Modulation of lung molecular biomarkers by beta-carotene in the Physicians' Health Study. (PubMed id 19142877)9 Liu C....Zhang S.M. (2009)
    1330. Unexpected DNA damage caused by polycyclic aromatic hydrocarbons under standard laboratory conditions. (PubMed id 18160334)9 Platt K.L....Fickler M. (2008)
    1331. Oestrogen producing enzymes and mammary carcinogenesis: a review. (PubMed id 17934808)9 Subramanian A....Mokbel K. (2008)
    1332. Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size. (PubMed id 17920237)9 Pushparajah D.S....Ioannides C. (2008)
    1333. Curcumin attenuates cytochrome P450 induction in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin by ROS-dependently degrading AhR and ARNT. (PubMed id 19018768)9 Choi H....Park J.W. (2008)
    1334. BRCA1 modulates sensitivity to 5F-203 by regulating xenobiotic stress-inducible protein levels and EROD activity. (PubMed id 18074135)9 Kang H.J....Bae I. (2008)
    1335. Preferential induction of cytochrome P450 1A1 over cy