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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CYHR1 Gene

protein-coding   GIFtS: 46
GCID: GC08M145674

Cysteine/Histidine-Rich 1

(Previous name: cysteine and histidine rich 1)
  Search for CYHR1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cysteine/Histidine-Rich 11 2
Cysteine And Histidine Rich 11 2
CHRP2
Cysteine And Histidine Rich Protein2
Cysteine And Histidine-Rich Protein 12
KIAA04963

External Ids:    HGNC: 178061   Entrez Gene: 506262   Ensembl: ENSG000001879547   UniProtKB: Q6ZMK13   

Export aliases for CYHR1 gene to outside databases

Previous GC identifers: GC08U990106 GC08M145646 GC08M145660 GC08M140788


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CYHR1 Gene: 
CYHR1 (cysteine/histidine-rich 1) is a protein-coding gene. GO annotations related to this gene include zinc ion binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_037704.5  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CYHR1 gene promoter:
         Sp1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCYHR1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CYHR1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYHR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.3   Ensembl cytogenetic band:  8q24.3   HGNC cytogenetic band: 8q24

CYHR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CYHR1 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M145674:  view genomic region     (about GC identifiers)

Start:
145,674,965 bp from pter      End:
145,691,060 bp from pter
Size:
16,096 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CYHR1_HUMAN, Q6ZMK1 (See protein sequence)
Recommended Name: Cysteine and histidine-rich protein 1  
Size: 362 amino acids; 40703 Da
Subunit: Interacts with LGALS3 (By similarity)
Subcellular location: Cytoplasm (By similarity). Cytoplasm, perinuclear region (By similarity). Note=Shows a
prominent perinuclear and cytoplasmic localization (By similarity)
Sequence caution: Sequence=BAD18724.1; Type=Erroneous initiation;
Secondary accessions: B3KSX0 D3DWM3 Q9BSF6 Q9BSU6
Alternative splicing: 4 isoforms:  Q6ZMK1-1   Q6ZMK1-2   Q6ZMK1-3   Q6ZMK1-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CYHR1: NX_Q6ZMK1

Explore proteomics data for CYHR1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZMK1

  • CYHR1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CYHR1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001123360.1  NP_116076.1  NP_612505.1  

    ENSEMBL proteins: 
     ENSP00000387426   ENSP00000433769   ENSP00000434470   ENSP00000385962   ENSP00000414647  
     ENSP00000304826   ENSP00000432902   ENSP00000434642  

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    Novus Biologicals CYHR1 Protein
    Novus Biologicals CYHR1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CYHR1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope IEA--
    GO:0005737cytoplasm ----
    GO:0048471perinuclear region of cytoplasm IEA--

    CYHR1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR008974 TRAF-like
     IPR013083 Znf_RING/FYVE/PHD
     IPR001293 Znf_TRAF

    Graphical View of Domain Structure for InterPro Entry Q6ZMK1

    ProtoNet protein and cluster: Q6ZMK1

    UniProtKB/Swiss-Prot: CYHR1_HUMAN, Q6ZMK1
    Similarity: Belongs to the CYHR1 family
    Similarity: Contains 1 RING-type zinc finger
    Similarity: Contains 1 TRAF-type zinc finger


    CYHR1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
         
    CYHR1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CYHR1:
     Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CYHR1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CYHR1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CYHR1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CYHR1 

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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate CYHR1:
    hsa-miR-3166 hsa-miR-4279 hsa-miR-4273
    SwitchGear 3'UTR luciferase reporter plasmidCYHR1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYHR1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CYHR1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/11 Interacting proteins for CYHR1 (Q6ZMK13 ENSP000003874264) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ECHS1P300843, ENSP000003575354I2D: score=1 STRING: ENSP00000357535
    LGALS3P179313, ENSP000002543014I2D: score=1 STRING: ENSP00000254301
    COPS4Q9BT783I2D: score=5 
    SCP2P223073I2D: score=5 
    UBE2KP610863I2D: score=5 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CYHR1

    Search CenterWatch for drugs/clinical trials and news about CYHR1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CYHR1 gene (3 alternative transcripts): 
    NM_001129888.1  NM_032687.3  NM_138496.1  

    Unigene Cluster for CYHR1:

    Cysteine/histidine-rich 1
    Hs.459379  [show with all ESTs]
    Unigene Representative Sequence: AB007965
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000528663 ENST00000438911(uc003zcv.2) ENST00000530374 ENST00000526887
    ENST00000533173 ENST00000528558 ENST00000403000(uc003zcx.2) ENST00000424149(uc003zcy.2)
    ENST00000306145(uc003zcw.2) ENST00000533764 ENST00000530637 ENST00000524623

    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate CYHR1:
    hsa-miR-3166 hsa-miR-4279 hsa-miR-4273
    SwitchGear 3'UTR luciferase reporter plasmidCYHR1 3' UTR sequence
    Inhib. RNA
    Products:
         
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    GenScript: all cDNA clones in your preferred vector (see all 3): CYHR1 (NM_138496)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CYHR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYHR1
    Sirion Biotech Customized lentivirus for stable overexpression of CYHR1 
                         Customized lentivirus expression plasmids for stable overexpression of CYHR1 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYHR1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYHR1

    Additional mRNA sequence: 

    AB007965.1 AK094514.1 AK160381.1 BC004544.2 BC005073.1 BC056412.1 BC065484.1 

    14 DOTS entries:

    DT.97862092  DT.313040  DT.75122970  DT.40194945  DT.443215  DT.92422079  DT.92422088  DT.95271126 
    DT.97862091  DT.100036735  DT.91661729  DT.100754297  DT.86854373  DT.92422081 

    24/254 AceView cDNA sequences (see all 254):

    BU630101 BU631223 BQ448263 BM695235 AI982764 BM974393 BM926524 AI362779 
    AI318085 BU500940 BM810596 CD671578 AI056793 AI479794 BM797552 BM710073 
    BM671891 AA402968 BM832785 CK819067 BM313717 BM042303 AW169601 BM908508 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for CYHR1 (see all 11)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3a · 3b ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b
    SP1:                                                                                -     -     -     -     -                       -               
    SP2:                                      -                 -     -     -     -     -     -     -     -     -                                       
    SP3:                                                                                                        -                       -               
    SP4:        -     -     -     -     -     -                                                                                                         
    SP5:                                -     -                                                                                                         


    ECgene alternative splicing isoforms for CYHR1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CYHR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGCTGGCAG
    CYHR1 Expression
    About this image


    See CYHR1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CYHR1

    SOURCE GeneReport for Unigene cluster: Hs.459379
        SABiosciences Custom PCR Arrays for CYHR1
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYHR1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CYHR1 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cyhr11 , 5 cysteine and histidine rich 11, 5 89.82(n)1
    96.14(a)1
      15 (36.20 cM)5
    541511  NM_019396.21  NP_062269.11 
     766433955 
    lizard
    (Anolis carolinensis)
    Reptilia CYHR16
    cysteine/histidine-rich 1
    57(a)
    1 ↔ 1
    GL343892.1(2190-20845)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1530611 zgc:153061 80.71(n)
    86.43(a)
      767773  NM_001076740.1  NP_001070208.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG324861 CG32486 58.59(n)
    52.22(a)
      38367  NM_139508.2  NP_647765.1 


    ENSEMBL Gene Tree for CYHR1 (if available)
    TreeFam Gene Tree for CYHR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/400 SNPs in CYHR1 are shown (see all 400)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2016400671,2
    C--140805957(+) CTGGGC/TCCACC 1 -- us2k10--------
    rs2009688531,2
    --140805959(+) GGGCCC/TACCCT 1 -- us2k10--------
    rs1421248801,2
    C--140805960(+) GGCCCA/GCCCTA 1 -- us2k10--------
    rs1460573511,2
    C--140805962(+) CCCACC/TCTACT 1 -- us2k11Minor allele frequency- T:0.00EU 1299
    rs2000971751,2
    C--140805966(+) CCCTAC/TTCCAG 1 -- us2k10--------
    rs2001989631,2
    --140806146(+) GATTGC/TCGGCT 1 -- us2k10--------
    rs1997062661,2
    C--140806147(+) ATTGCC/TGGCTG 1 -- us2k10--------
    rs1914432381,2
    --145674873(+) CCAGGC/TGCCCA 1 -- ds50010--------
    rs1158081511,2
    F--145674911(+) CTGGGG/AACGCT 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs1479544831,2
    --145675002(+) TTAATC/TTTTTT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for CYHR1 (145674965 - 145691060 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/32 variations for CYHR1 (see all 32):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1003467CNV Deletion20482838
    dgv907n27CNV Loss19166990
    dgv7966n71CNV Loss21882294
    dgv7977n71CNV Loss21882294
    dgv7976n71CNV Loss21882294
    nsv891841CNV Loss21882294
    dgv7978n71CNV Loss21882294
    dgv7980n71CNV Loss21882294
    nsv891846CNV Loss21882294
    nsv891817CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CYHR1 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with CYHR1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Interaction of a novel cysteine and histidine-rich cytoplasmic protein with galectin-3 in a carbohydrate-independent manner. (PubMed id 10745073)1, 3 Menon R.P....Hughes R.C. (2000)
    3. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PubMed id 9455484)1, 2 Seki N.... Ohara O. (1997)
    4. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    5. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 50626 HGNC: 17806 AceView: CYHR1 Ensembl:ENSG00000187954 euGenes: HUgn50626
    ECgene: CYHR1 H-InvDB: CYHR1

    (According to HUGE)
    About This Section
    HUGE: KIAA0496

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CYHR1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CYHR1 gene:
    Search GeneIP for patents involving CYHR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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