Aliases for CYC1 Gene
External Ids for CYC1 Gene
Previous GeneCards Identifiers for CYC1 Gene
This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6. [provided by RefSeq, Dec 2013]
GeneCards Summary for CYC1 Gene
CYC1 (Cytochrome C-1) is a Protein Coding gene. Diseases associated with CYC1 include mitochondrial complex iii deficiency, nuclear type 6 and mitochondrial complex iii deficiency. Among its related pathways are Metabolism and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include iron ion binding and electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity.
UniProtKB/Swiss-Prot for CYC1 Gene
This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain