CYB5R4 Gene
protein-coding GIFtS: 55
GCID: GC06P084569
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|
cytochrome b5 reductase 4(Previous name: NADPH cytochrome B5 oxidoreductase )
(Previous symbol: NCB5OR)
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Aliases
for CYB5R4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cytochrome B5 Reductase 41 2 | | Cb5/Cb5R1 | | NCB5OR1 2 3 5 | | N-Terminal Cytochrome B5 And Cytochrome B5 Oxidoreductase Domain-ContainingProtein2 3 | | DJ676J13.11 | | EC 1.6.2.23 8 | | NADPH Cytochrome B5 Oxidoreductase1 2 | | RP4-676J13.12 | | B5+B5R1 | | Cytochrome B-Type NAD(P)H Oxidoreductase2 | | Flavohemoprotein B5/B5R2 3 | | Flavohemoprotein B5+B5R2 |
Export aliases for CYB5R4 gene to outside databasesPrevious GC identifers: GC06P084627 GC06P081798 |
Summaries
for CYB5R4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CYB5R4:
NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A; MIM 613218) and CYB5reductase (CYB5R3; MIM 613213) (Zhu et al., 1999 (PubMed 10611283)).(supplied by OMIM, Jan 2010)
UniProtKB/Swiss-Prot: NB5R4_HUMAN, Q7L1T6Function: NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical rolein protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup ofreactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide andmethemoglobin
Gene Wiki entry for CYB5R4
|
Genomic Views
for CYB5R4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007299.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CYB5R4 gene promoter:
SREBP-1c POU3F2 (N-Oct-5a) POU6F1 (c2) Cdc5 SREBP-1b S8 Ik-2 SREBP-1a Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CYB5R4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYB5R4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6pter-q22.33 Ensembl cytogenetic band: 6q14.2 HGNC cytogenetic band: 6q14.2CYB5R4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P084569: view genomic region
(about GC identifiers)
Start:
|
84,569,362 bp from pter |
End:
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84,670,146 bp from pter |
Size:
|
100,785 bases |
Orientation:
|
plus strand |
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Proteins
for CYB5R4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NB5R4_HUMAN, Q7L1T6 (See
protein sequence)Recommended Name: Cytochrome b5 reductase 4 Size: 521 amino acids; 59474 Da
Cofactor: FAD
Subcellular location: Endoplasmic reticulum. Note=Soluble protein
Sequence caution: Sequence=AAF04812.1; Type=Erroneous initiation; Sequence=CAI19905.1; Type=Erroneous gene modelprediction; Sequence=CAI22326.1; Type=Erroneous gene model prediction;
1 PDB 3D structure from  and Proteopedia  for CYB5R4:3LF5 (3D)
Secondary accessions: B1AEM2 Q5TGI9 Q9NUE4 Q9UHI9Explore the universe of human proteins at neXtProt for CYB5R4: NX_Q7L1T6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7L1T6
4/7 DME Specific Peptides for CYB5R4 (Q7L1T6) (see all 7)
CYB5R4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057314.2
ENSEMBL proteins: ENSP00000358695 ENSP00000358693
Human Recombinant Protein Products for CYB5R4:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
CYB5R4 for ontologies About GeneDecksing
CYB5R4 Antibody Products:
Assay Products for CYB5R4: |
Protein
Domains /
Families
for CYB5R4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CYB5R4 for domains About GeneDecksing
5/10 InterPro domains/families (see all 10):Graphical View of Domain Structure for InterPro Entry Q7L1T6ProtoNet protein and cluster: Q7L1T6 5 Blocks protein families: IPB001199 Cytochrome b5 IPB001433 Oxidoreductase FAD/NAD(P)-binding IPB001834 Cytochrome B5 reductase signature IPB007052 CS domain IPB008333 Oxidoreductase FAD-binding region
UniProtKB/Swiss-Prot: NB5R4_HUMAN, Q7L1T6Similarity: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase familySimilarity: Contains 1 CS domainSimilarity: Contains 1 cytochrome b5 heme-binding domainSimilarity: Contains 1 FAD-binding FR-type domain |
Function
for CYB5R4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: NB5R4_HUMAN, Q7L1T6Function: NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical rolein protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup ofreactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide andmethemoglobinCatalytic activity: NADH + 2 ferricytochrome b5 = NAD(+) + H(+) + 2 ferrocytochrome b5Biophysicochemical properties: Kinetic parameters: KM=25 mM for O(2); Redox potential: E(0) is -108 mV; Enzyme Number (IUBMB): EC 1.6.2.21 2
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
CYB5R4 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for CYB5R4:
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Cyb5r4):
CYB5R4 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Cyb5r4tm1Hfb for CYB5R4
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5R4 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5R4 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CYB5R4 (NM_016230) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CYB5R4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYB5R4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYB5R4 |
|
Pathways & Interactions
for CYB5R4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cytochrome P450 - arranged by substrate type | |
1  BioSystems Pathway for CYB5R4
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CYB5R4
1 Interacting protein for CYB5R4 (Q7L1T63) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
CYB5R4 for ontologies About GeneDecksing
|
Drugs & Compounds
for CYB5R4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CYB5R4
4 HMDB Compounds for CYB5R4 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| FAD | 1H-Purin-6-amine flavin dinucleotide (see all 21) | 146-14-5 | -- | | Heme | (protoporphyrinato)iron (see all 19) | 14875-96-8 | -- | | NAD | 3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28) | 53-84-9 | -- | | NADH | 1,4-Dihydronicotinamide adenine dinucleotide (see all 17) | 58-68-4 | -- |
Search CenterWatch for drugs/clinical trials and news about CYB5R4 / NB5R4
|
Transcripts
for CYB5R4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CYB5R4 gene: NM_016230.3 Unigene Cluster for CYB5R4: Cytochrome b5 reductase 4 Hs.5741 [show with all ESTs]Unigene Representative Sequence: NM_0162303 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369681(uc003pkf.3) ENST00000369679 ENST00000479164
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5R4 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5R4 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CYB5R4 (NM_016230) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CYB5R4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYB5R4 |
Additional cDNA sequence: AF169803.1 AK313146.1 AL832113.1 BC025380.1 BC029339.1 5 DOTS entries: DT.114378 DT.92423325 DT.95245933 DT.121354473 DT.91873348 24/91 AceView cDNA sequences (see all 91): BC025380 AI911592 BF515025 BQ045415 BI059778 CA450414 AA287189 AA600147 AA808031 AI027183 AI286063 R36810 R70025 AA287098 AF169803 AA402753 BC029339 CB131642 AI377981 AA383050 BQ212318 AA400638 BQ434535 CB052177
GeneLoc Exon Structure
|
Expression
for CYB5R4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CYB5R4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCTATGCT
About this image
See CYB5R4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CYB5R4
SOURCE GeneReport for Unigene cluster: Hs.5741
UniProtKB/Swiss-Prot: NB5R4_HUMAN, Q7L1T6Tissue specificity: Widely expressed
SABiosciences Custom PCR Arrays for CYB5R4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYB5R4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CYB5R4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYB5R4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYB5R4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYB5R4 |
Orthologs
for CYB5R4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CYB5R4 gene from 8/25 species (see all 25) About this table
ENSEMBL Gene Tree for CYB5R4 (if available)
TreeFam Gene Tree for CYB5R4 (if available) |
Paralogs
for CYB5R4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CYB5R4 gene
- CYB5R32 CYB5R22 CYB5R12
3 SIMAP similar genes for CYB5R4 using alignment to 1 protein entry: NB5R4_HUMAN:CYB5A DKFZp686M0619 CYB5R3
CYB5R4 for paralogs About GeneDecksing
|
Genomic Variants
for CYB5R4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: NB5R4_HUMAN, Q7L1T6Polymorphism: Variants Arg-187 and Arg-223 do not influence the pathogenesis of non-autoimmune diabetes
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CYB5R4 (84569362 - 84670146 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CYB5R4: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYB5R4 |
|
Disorders
/ Diseases
for CYB5R4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CYB5R4 for disorders About GeneDecksing
OMIM gene information: 608343
OMIM disorders: --
6  diseases for CYB5R4: About MalaCardsmaturity-onset diabetes of the young methemoglobinemia gestational diabetes diabetes mellitus
pancreatitis malaria
1 disease from the University of Copenhagen DISEASES database for CYB5R4:Methemoglobinemia Genetic Association Database (GAD): CYB5R4
Human Genome Epidemiology (HuGE) Navigator: CYB5R4 (5 documents)
Export disorders for CYB5R4 gene to outside databases
|
Publications
for CYB5R4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CYB5R4 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with CYB5R4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells. (PubMed id 10611283)1, 2, 3, 9 Zhu H.... Bunn H.F. (1999)
- Variation in NCB5OR: studies of relationships to type 2 diabetes, maturity-onset diabetes of the young, and gestational diabetes mellitus. (PubMed id 15504981)1, 2, 4 Andersen G.... Pedersen O. (2004)
- NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum. (PubMed id 15131110)1, 2, 9 Zhu H.... Bunn H.F. (2004)
- Study of the individual cytochrome b5 and cytochrome b5 reductase domains of Ncb5or reveals a unique heme pocket and a possible role of the CS domain. (PubMed id 20630863)1, 2 Deng B....Zhu H. (2010)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Methemoglobin reductase deficiency: novel mutation is associated with a disease phenotype of intermediate severity. (PubMed id 22627575)1 Percy M.J....Lappin T.R. (2012)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
|
External Searches for CYB5R4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CYB5R4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CYB5R4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CYB5R4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CYB5R4 | Pharmacogenomics, SNPs, Pathways | | SeattleSNPs | http://pga.gs.washington.edu/data/cyb5r4/ |
|
| | |
About This Section
| Patent Information for CYB5R4 gene:
Search GeneIP for patents involving CYB5R4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CYB5R4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CYB5R4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CYB5R4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYB5R4 | | | OriGene Protein Over-expression Lysate for CYB5R4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CYB5R4 | | OriGene 3'-UTR Clone for CYB5R4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5R4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5R4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CYB5R4 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CYB5R4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYB5R4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYB5R4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CYB5R4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYB5R4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYB5R4 |
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| |  |  |  |  | | | | |
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 | | | CYB5R4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYB5R4 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for CYB5R4 |
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