CYB5B Gene
protein-coding GIFtS: 51
GCID: GC16P069458
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cytochrome b5 type B (outer mitochondrial membrane)
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Aliases
for CYB5B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cytochrome B5 Type B (Outer Mitochondrial Membrane)1 2 | | Cytochrome B5 Type B2 | | CYB5-M1 2 | | Outer Mitochondrial Membrane Cytochrome B52 | | Cytochrome B5 Outer Mitochondrial Membrane Isoform2 3 | | Type 2 Cyt-B52 | | OMB52 3 | | CYB5M3 | | CYPB5M2 5 | | |
Export aliases for CYB5B gene to outside databasesPrevious GC identifers: GC16P068017 GC16P055336 |
Summaries
for CYB5B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: CYB5B_HUMAN, O43169Function: Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membranebound oxygenases (By similarity)
|
Genomic Views
for CYB5B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CYB5B gene promoter:
PPAR-alpha POU2F1 GCNF-1 GCNF POU2F1a XBP-1 GCNF-2 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for CYB5B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYB5B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q22.1 Ensembl cytogenetic band: 16q22.1 HGNC cytogenetic band: 16q22.1CYB5B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P069458: view genomic region
(about GC identifiers)
Start:
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69,458,428 bp from pter |
End:
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69,500,169 bp from pter |
Size:
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41,742 bases |
Orientation:
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plus strand |
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Proteins
for CYB5B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CYB5B_HUMAN, O43169 (See
protein sequence)Recommended Name: Cytochrome b5 type B precursor Size: 146 amino acids; 16332 Da
Subunit: Component of a complex composed of cytochrome b5, NADH-cytochrome b5 reductase (CYB5R3) and MOSC2 (Bysimilarity)
Subcellular location: Mitochondrion outer membrane (By similarity)
1 PDB 3D structure from  and Proteopedia  for CYB5B:3NER (3D)
Secondary accessions: A8K6B1 Q96CC3 Q9BT35Explore the universe of human proteins at neXtProt for CYB5B: NX_O43169
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43169
CYB5B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_085056.2
ENSEMBL proteins: ENSP00000423679 ENSP00000421492 ENSP00000457848 ENSP00000464102 ENSP00000308430
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
CYB5B for ontologies About GeneDecksing
CYB5B Antibody Products:
Assay Products for CYB5B: |
Protein
Domains /
Families
for CYB5B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CYB5B for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O43169ProtoNet protein and cluster: O43169 2 Blocks protein families: IPB000425 MIP family IPB001199 Cytochrome b5
UniProtKB/Swiss-Prot: CYB5B_HUMAN, O43169Similarity: Belongs to the cytochrome b5 familySimilarity: Contains 1 cytochrome b5 heme-binding domain |
Function
for CYB5B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CYB5B_HUMAN, O43169Function: Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membranebound oxygenases (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5B (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CYB5B (NM_030579) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CYB5B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYB5B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYB5B |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
CYB5B for ontologies About GeneDecksing
|
Pathways & Interactions
for CYB5B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cytochrome P450 - arranged by substrate type | |
1  BioSystems Pathway for CYB5B
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CYB5B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/10 Interacting proteins for CYB5B (O431693 ENSP000003084304) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0022900 | electron transport chain |
IEA | -- | | GO:0043085 | positive regulation of catalytic activity |
-- | -- |
CYB5B for ontologies About GeneDecksing
|
Drugs & Compounds
for CYB5B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CYB5B
2 HMDB Compounds for CYB5B About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Heme | (protoporphyrinato)iron (see all 19) | 14875-96-8 | -- | | NADH | 1,4-Dihydronicotinamide adenine dinucleotide (see all 17) | 58-68-4 | -- |
1 DrugBank Compound for CYB5B About this table
| Compound | Synonyms |
CAS
# | Type | Actions | PubMed Ids |
|---|
| Heme | -- | -- | target | -- | 10592235 |
Search CenterWatch for drugs/clinical trials and news about CYB5B
|
Transcripts
for CYB5B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CYB5B gene: NM_030579.2 Unigene Cluster for CYB5B: Cytochrome b5 type B (outer mitochondrial membrane) Hs.461131 [show with all ESTs]Unigene Representative Sequence: NM_0305797 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000512062 ENST00000514123(uc002exf.3) ENST00000515314 ENST00000561792
ENST00000568237 ENST00000568342 ENST00000307892(uc002exg.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5B (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CYB5B (NM_030579) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CYB5B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYB5B |
Additional cDNA sequence: AB009282.1 AK098148.1 AK125218.1 AK291576.1 BC004373.1 BC014431.1 BX647922.1 23 DOTS entries: DT.449306 DT.215773 DT.40296863 DT.40108515 DT.40309814 DT.100669038 DT.86854166 DT.100038777 DT.91666487 DT.95211082 DT.95354561 DT.100669047 DT.100669049 DT.100702091 DT.120703370 DT.120703382 DT.120703421 DT.120703424 DT.75114140 DT.92450701 DT.100669035 DT.100857944 DT.100866475 24/527 AceView cDNA sequences (see all 527): BQ228352 BG680476 BI869460 AW136772 BE503557 BX114608 BI260975 BM771349 BE645922 AA769471 CR591474 BM760116 BM911227 AI433610 BQ231782 R84501 BQ712189 BE268220 CA395624 BQ645199 BI908230 AW439438 BU507105 AA765730
GeneLoc Exon Structure
|
Expression
for CYB5B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CYB5B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGAATAAAAT
About this image
See CYB5B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CYB5B
SOURCE GeneReport for Unigene cluster: Hs.461131
SABiosciences Custom PCR Arrays for CYB5B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYB5B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CYB5B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYB5B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYB5B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYB5B |
Orthologs
for CYB5B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CYB5B gene from 10/30 species (see all 30) About this table
ENSEMBL Gene Tree for CYB5B (if available)
TreeFam Gene Tree for CYB5B (if available) |
Paralogs
for CYB5B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CYB5B gene
- CYB5A2
5 SIMAP similar genes for CYB5B using alignment to 5 protein entries: CYB5B_HUMAN (see all proteins):DKFZp686M0619 CYB5A FADS1 FA2H SUOX
CYB5B for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CYB5B
PGOHUM00000247109
|
Genomic Variants
for CYB5B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CYB5B (69458428 - 69500169 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CYB5B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYB5B |
|
Disorders
/ Diseases
for CYB5B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CYB5B for disorders About GeneDecksing
OMIM gene information: 611964
OMIM disorders: --
8  diseases for CYB5B: About MalaCardsnorth american indian childhood cirrhosis non-hodgkin lymphoma optic atrophy hodgkin's lymphoma
hepatocellular carcinoma carcinoma malaria neuronitis
Human Genome Epidemiology (HuGE) Navigator: CYB5B (1 document)
Export disorders for CYB5B gene to outside databases
|
Publications
for CYB5B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CYB5B gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with CYB5B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mammalian mitochondrial and microsomal cytochromes b(5) exhibit divergent structural and biophysical characteristics. (PubMed id 14733950)1, 3 Altuve A....Rivera M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Assessment of the ability of type 2 cytochrome b5 to modulate 17,20-lyase activity of human P450c17. (PubMed id 11867265)1, 3 Soucy P. and Luu-The V. (2002)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- The interaction between ubiquitin C-terminal hydrolas e 37 and glucose-regulated protein 78 in hepatocellular carcinoma. (PubMed id 21800051)1 Fang Y....Shen X. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Accommodating a nonconservative internal mutation by water-mediated hydrogen bonding between I^-sheet strands: a comparison of human and rat type B (mitochondrial) cytochrome b5. (PubMed id 21574570)1 Parthasarathy S....Benson D.R. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for CYB5B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CYB5B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CYB5B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CYB5B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CYB5B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CYB5B gene:
Search GeneIP for patents involving CYB5B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CYB5B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CYB5B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CYB5B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CYB5B | | | OriGene Protein Over-expression Lysate for CYB5B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CYB5B | | OriGene 3'-UTR Clone for CYB5B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CYB5B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CYB5B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CYB5B | | OriGene Custom Protein Services for CYB5B | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CYB5B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CYB5B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CYB5B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CYB5B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CYB5B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CYB5B |
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 |  |  |  | |
| | | | Search Tocris compounds for CYB5B |
| |  |  |  |  | | | | |
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 | | | CYB5B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CYB5B |
|  |  |  | | | | Search ThermoFisher Antibodies for CYB5B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CYB5B |
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